Novel motif:96

name:	motif96_TKNTTCTGTCTN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0003008	system process	2.089892e-21
GO:0023052	signaling	4.976401e-18
GO:0032501	multicellular organismal process	4.421862e-17
GO:0007154	cell communication	4.618176e-17
GO:0050896	response to stimulus	7.892871e-16
GO:0051716	cellular response to stimulus	1.265020e-14
GO:0006955	immune response	2.509326e-14
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5.154525e-14
GO:0007165	signal transduction	1.309458e-13
GO:0050877	neurological system process	2.746382e-13
GO:0007186	G-protein coupled receptor protein signaling pathway	5.672003e-13
GO:0002376	immune system process	7.036346e-13
GO:0042137	sequestering of neurotransmitter	7.537312e-13
GO:0006950	response to stress	1.419313e-12
GO:0042221	response to chemical stimulus	1.670595e-12
GO:0007166	cell surface receptor linked signaling pathway	1.727098e-12
GO:0007268	synaptic transmission	1.759069e-12
GO:0019226	transmission of nerve impulse	3.410145e-12
GO:0006952	defense response	8.880224e-12
GO:0051592	response to calcium ion	1.702873e-11
GO:0002694	regulation of leukocyte activation	5.379327e-11
GO:0007267	cell-cell signaling	5.381554e-11
GO:0002861	regulation of inflammatory response to antigenic stimulus	8.693295e-11
GO:0010466	negative regulation of peptidase activity	9.743161e-11
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.854656e-10
GO:0051336	regulation of hydrolase activity	1.865434e-10
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	4.710089e-10
GO:0002768	immune response-regulating cell surface receptor signaling pathway	4.867063e-10
GO:0052547	regulation of peptidase activity	5.331731e-10
GO:0002696	positive regulation of leukocyte activation	6.181913e-10
GO:0009611	response to wounding	8.221721e-10
GO:0012501	programmed cell death	8.667772e-10
GO:0016525	negative regulation of angiogenesis	8.979586e-10
GO:0043537	negative regulation of blood vessel endothelial cell migration	9.430412e-10
GO:0050865	regulation of cell activation	9.706182e-10
GO:0006915	apoptosis	1.014817e-9
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.503555e-9
GO:0002885	positive regulation of hypersensitivity	3.796770e-9
GO:0001775	cell activation	4.250430e-9
GO:0043154	negative regulation of caspase activity	4.596179e-9
GO:0051346	negative regulation of hydrolase activity	5.341243e-9
GO:0043652	engulfment of apoptotic cell	5.614697e-9
GO:0010754	negative regulation of cGMP-mediated signaling	5.614697e-9
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.614697e-9
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	5.614697e-9
GO:0010751	negative regulation of nitric oxide mediated signal transduction	5.614697e-9
GO:0006936	muscle contraction	5.880251e-9
GO:0032655	regulation of interleukin-12 production	8.866283e-9
GO:0010035	response to inorganic substance	8.928416e-9
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	9.758465e-9
GO:0040040	thermosensory behavior	1.013545e-8
GO:0002883	regulation of hypersensitivity	1.103715e-8
GO:0010942	positive regulation of cell death	1.124280e-8
GO:0002764	immune response-regulating signaling pathway	1.162093e-8
GO:0050867	positive regulation of cell activation	1.485544e-8
GO:0015671	oxygen transport	1.579737e-8
GO:0070265	necrotic cell death	1.707096e-8
GO:0016265	death	1.820940e-8
GO:0007616	long-term memory	2.090943e-8
GO:0008219	cell death	2.239576e-8
GO:0002922	positive regulation of humoral immune response	2.277389e-8
GO:0010763	positive regulation of fibroblast migration	2.294939e-8
GO:0032891	negative regulation of organic acid transport	2.401980e-8
GO:0042534	regulation of tumor necrosis factor biosynthetic process	2.459473e-8
GO:0050680	negative regulation of epithelial cell proliferation	2.467376e-8
GO:0009266	response to temperature stimulus	2.480905e-8
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.529210e-8
GO:0007431	salivary gland development	2.723897e-8
GO:0007163	establishment or maintenance of cell polarity	2.877369e-8
GO:0052548	regulation of endopeptidase activity	3.451481e-8
GO:0032026	response to magnesium ion	3.742953e-8
GO:0001798	positive regulation of type IIa hypersensitivity	4.321201e-8
GO:0030185	nitric oxide transport	4.764011e-8
GO:0043065	positive regulation of apoptosis	6.431898e-8
GO:0070613	regulation of protein processing	7.861664e-8
GO:0032800	receptor biosynthetic process	8.913196e-8
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	8.914603e-8
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.090427e-7
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.261650e-7
GO:0006917	induction of apoptosis	1.329450e-7
GO:0065007	biological regulation	1.454935e-7
GO:0002920	regulation of humoral immune response	1.791541e-7
GO:0007249	I-kappaB kinase/NF-kappaB cascade	1.959169e-7
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.108943e-7
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	2.108943e-7
GO:0030011	maintenance of cell polarity	2.120960e-7
GO:0034616	response to laminar fluid shear stress	2.154791e-7
GO:0012502	induction of programmed cell death	2.157222e-7
GO:0010596	negative regulation of endothelial cell migration	2.472627e-7
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	2.518359e-7
GO:0032369	negative regulation of lipid transport	2.697119e-7
GO:0006968	cellular defense response	2.896151e-7
GO:0007612	learning	2.918077e-7
GO:0009408	response to heat	3.015429e-7
GO:0050789	regulation of biological process	3.379857e-7
GO:0050851	antigen receptor-mediated signaling pathway	3.534778e-7
GO:2000116	regulation of cysteine-type endopeptidase activity	3.564586e-7
GO:0015669	gas transport	3.593918e-7
GO:0050778	positive regulation of immune response	3.674792e-7
GO:0045994	positive regulation of translational initiation by iron	3.852589e-7
GO:0002037	negative regulation of L-glutamate transport	3.852589e-7
GO:0050729	positive regulation of inflammatory response	3.977811e-7
GO:0043068	positive regulation of programmed cell death	4.018144e-7
GO:0043032	positive regulation of macrophage activation	4.218992e-7
GO:0051023	regulation of immunoglobulin secretion	4.315422e-7
GO:0006911	phagocytosis, engulfment	4.613942e-7
GO:0034097	response to cytokine stimulus	4.872236e-7
GO:0042981	regulation of apoptosis	4.921808e-7
GO:0045087	innate immune response	5.254680e-7
GO:0071675	regulation of mononuclear cell migration	5.660169e-7
GO:0051017	actin filament bundle assembly	5.812070e-7
GO:0032943	mononuclear cell proliferation	5.900580e-7
GO:0010836	negative regulation of protein ADP-ribosylation	5.974710e-7
GO:0006813	potassium ion transport	6.074224e-7
GO:0002757	immune response-activating signal transduction	6.243858e-7
GO:0002684	positive regulation of immune system process	6.949516e-7
GO:0070301	cellular response to hydrogen peroxide	7.418697e-7
GO:0051533	positive regulation of NFAT protein import into nucleus	7.831529e-7
GO:0010755	regulation of plasminogen activation	8.127222e-7
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	8.776367e-7
GO:0032695	negative regulation of interleukin-12 production	9.584812e-7
GO:0034762	regulation of transmembrane transport	9.641472e-7
GO:0051895	negative regulation of focal adhesion assembly	9.653571e-7
GO:0002449	lymphocyte mediated immunity	9.846496e-7
GO:0007435	salivary gland morphogenesis	1.014661e-6
GO:0010033	response to organic substance	1.032407e-6
GO:0045948	positive regulation of translational initiation	1.062186e-6
GO:0002544	chronic inflammatory response	1.100909e-6
GO:0035418	protein localization to synapse	1.102935e-6
GO:0050892	intestinal absorption	1.138525e-6
GO:0015698	inorganic anion transport	1.225244e-6
GO:0010941	regulation of cell death	1.244268e-6
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.276415e-6
GO:0009628	response to abiotic stimulus	1.278869e-6
GO:0046600	negative regulation of centriole replication	1.281349e-6
GO:0006447	regulation of translational initiation by iron	1.375603e-6
GO:0009617	response to bacterium	1.381087e-6
GO:0071310	cellular response to organic substance	1.452601e-6
GO:0010759	positive regulation of macrophage chemotaxis	1.542775e-6
GO:0071844	cellular component assembly at cellular level	1.543147e-6
GO:0051897	positive regulation of protein kinase B signaling cascade	1.599838e-6
GO:0046651	lymphocyte proliferation	1.907282e-6
GO:0022612	gland morphogenesis	1.972530e-6
GO:0031349	positive regulation of defense response	1.996439e-6
GO:0032570	response to progesterone stimulus	2.119682e-6
GO:0043067	regulation of programmed cell death	2.244543e-6
GO:0002577	regulation of antigen processing and presentation	2.396059e-6
GO:0001666	response to hypoxia	2.478485e-6
GO:0010757	negative regulation of plasminogen activation	2.507603e-6
GO:0010758	regulation of macrophage chemotaxis	2.549567e-6
GO:0070661	leukocyte proliferation	2.565457e-6
GO:0002253	activation of immune response	2.594078e-6
GO:0002889	regulation of immunoglobulin mediated immune response	2.716353e-6
GO:0071345	cellular response to cytokine stimulus	2.771087e-6
GO:0051249	regulation of lymphocyte activation	2.817480e-6
GO:0032914	positive regulation of transforming growth factor beta1 production	2.838250e-6
GO:0002712	regulation of B cell mediated immunity	3.119374e-6
GO:0070887	cellular response to chemical stimulus	3.284172e-6
GO:0010038	response to metal ion	3.415523e-6
GO:0032103	positive regulation of response to external stimulus	3.602473e-6
GO:0016064	immunoglobulin mediated immune response	3.695864e-6
GO:0051606	detection of stimulus	4.042260e-6
GO:0050860	negative regulation of T cell receptor signaling pathway	4.076524e-6
GO:0003009	skeletal muscle contraction	4.380778e-6
GO:0065009	regulation of molecular function	4.381722e-6
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	4.381792e-6
GO:0002250	adaptive immune response	4.419745e-6
GO:0002675	positive regulation of acute inflammatory response	4.651826e-6
GO:0043030	regulation of macrophage activation	4.737080e-6
GO:0031508	centromeric heterochromatin formation	4.779515e-6
GO:0070482	response to oxygen levels	4.839373e-6
GO:0042742	defense response to bacterium	4.881928e-6
GO:0001819	positive regulation of cytokine production	4.884802e-6
GO:0071805	potassium ion transmembrane transport	5.013177e-6
GO:0051099	positive regulation of binding	5.222296e-6
GO:0050678	regulation of epithelial cell proliferation	5.260056e-6
GO:0043049	otic placode formation	5.832023e-6
GO:0050856	regulation of T cell receptor signaling pathway	6.487473e-6
GO:0018095	protein polyglutamylation	6.530890e-6
GO:0035272	exocrine system development	6.745652e-6
GO:0051707	response to other organism	6.886840e-6
GO:0031295	T cell costimulation	6.892089e-6
GO:0001970	positive regulation of activation of membrane attack complex	6.970397e-6
GO:0032502	developmental process	7.657012e-6
GO:0051953	negative regulation of amine transport	7.814977e-6
GO:0044341	sodium-dependent phosphate transport	7.894737e-6
GO:0051798	positive regulation of hair follicle development	7.908688e-6
GO:0009435	NAD biosynthetic process	8.023227e-6
GO:0006769	nicotinamide metabolic process	8.046764e-6
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	8.105362e-6
GO:0050852	T cell receptor signaling pathway	8.202776e-6
GO:0051896	regulation of protein kinase B signaling cascade	8.272271e-6
GO:0007620	copulation	8.568834e-6
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	8.922110e-6
GO:0018149	peptide cross-linking	9.144292e-6
GO:0071803	positive regulation of podosome assembly	1.004808e-5
GO:0002576	platelet degranulation	1.014610e-5
GO:0032205	negative regulation of telomere maintenance	1.022218e-5
GO:0050794	regulation of cellular process	1.121158e-5
GO:0051704	multi-organism process	1.156664e-5
GO:0031110	regulation of microtubule polymerization or depolymerization	1.180556e-5
GO:0002739	regulation of cytokine secretion involved in immune response	1.200647e-5
GO:0019363	pyridine nucleotide biosynthetic process	1.207848e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.235315e-5
GO:0042744	hydrogen peroxide catabolic process	1.247175e-5
GO:0034330	cell junction organization	1.261640e-5
GO:0009187	cyclic nucleotide metabolic process	1.329994e-5
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	1.330743e-5
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.347404e-5
GO:0051918	negative regulation of fibrinolysis	1.448682e-5
GO:0002426	immunoglobulin production in mucosal tissue	1.450824e-5
GO:0009214	cyclic nucleotide catabolic process	1.453189e-5
GO:0006954	inflammatory response	1.472997e-5
GO:0010955	negative regulation of protein processing	1.526453e-5
GO:0051049	regulation of transport	1.638304e-5
GO:0009719	response to endogenous stimulus	1.659830e-5
GO:0003012	muscle system process	1.686781e-5
GO:0019674	NAD metabolic process	1.711833e-5
GO:0019724	B cell mediated immunity	1.726713e-5
GO:0002718	regulation of cytokine production involved in immune response	1.775543e-5
GO:0048856	anatomical structure development	1.791749e-5
GO:0009820	alkaloid metabolic process	1.880880e-5
GO:0002036	regulation of L-glutamate transport	1.882445e-5
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.921587e-5
GO:0046548	retinal rod cell development	1.936243e-5
GO:0009725	response to hormone stimulus	2.011069e-5
GO:0050727	regulation of inflammatory response	2.033345e-5
GO:0015705	iodide transport	2.107172e-5
GO:0042060	wound healing	2.112611e-5
GO:0046058	cAMP metabolic process	2.116029e-5
GO:0032438	melanosome organization	2.164273e-5
GO:0051293	establishment of spindle localization	2.184730e-5
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.234571e-5
GO:0009607	response to biotic stimulus	2.235708e-5
GO:0051251	positive regulation of lymphocyte activation	2.249044e-5
GO:0071622	regulation of granulocyte chemotaxis	2.279874e-5
GO:0006941	striated muscle contraction	2.284558e-5
GO:0031347	regulation of defense response	2.331245e-5
GO:0032211	negative regulation of telomere maintenance via telomerase	2.358541e-5
GO:0043114	regulation of vascular permeability	2.406686e-5
GO:0042094	interleukin-2 biosynthetic process	2.513603e-5
GO:0051917	regulation of fibrinolysis	2.528633e-5
GO:0046903	secretion	2.583062e-5
GO:0008156	negative regulation of DNA replication	2.748284e-5
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2.798369e-5
GO:0050830	defense response to Gram-positive bacterium	2.801728e-5
GO:0034329	cell junction assembly	2.944988e-5
GO:0044085	cellular component biogenesis	3.043340e-5
GO:0009268	response to pH	3.255315e-5
GO:0017157	regulation of exocytosis	3.274741e-5
GO:0006820	anion transport	3.301045e-5
GO:0045071	negative regulation of viral genome replication	3.439769e-5
GO:0048513	organ development	3.466971e-5
GO:0050854	regulation of antigen receptor-mediated signaling pathway	3.470804e-5
GO:0009593	detection of chemical stimulus	3.612889e-5
GO:0048545	response to steroid hormone stimulus	3.713726e-5
GO:0019359	nicotinamide nucleotide biosynthetic process	3.736173e-5
GO:0031646	positive regulation of neurological system process	3.810531e-5
GO:0002443	leukocyte mediated immunity	3.945059e-5
GO:0050798	activated T cell proliferation	4.043252e-5
GO:0007044	cell-substrate junction assembly	4.066280e-5
GO:0007091	mitotic metaphase/anaphase transition	4.129103e-5
GO:0034198	cellular response to amino acid starvation	4.195463e-5
GO:0001937	negative regulation of endothelial cell proliferation	4.197920e-5
GO:0006198	cAMP catabolic process	4.323625e-5
GO:0071034	CUT catabolic process	4.567762e-5
GO:0050776	regulation of immune response	4.777282e-5
GO:0072387	flavin adenine dinucleotide metabolic process	4.907494e-5
GO:0032940	secretion by cell	5.079832e-5
GO:0070884	regulation of calcineurin-NFAT signaling pathway	5.339730e-5
GO:0032844	regulation of homeostatic process	5.343993e-5
GO:0035710	CD4-positive, alpha-beta T cell activation	5.363543e-5
GO:0008588	release of cytoplasmic sequestered NF-kappaB	5.386621e-5
GO:0015672	monovalent inorganic cation transport	5.608666e-5
GO:0002683	negative regulation of immune system process	5.613209e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	5.654451e-5
GO:0060557	positive regulation of vitamin D biosynthetic process	5.697166e-5
GO:0043623	cellular protein complex assembly	5.702519e-5
GO:0051345	positive regulation of hydrolase activity	5.768014e-5
GO:0034333	adherens junction assembly	5.922790e-5
GO:0002682	regulation of immune system process	6.037530e-5
GO:0048753	pigment granule organization	6.100472e-5
GO:0051797	regulation of hair follicle development	6.132648e-5
GO:0030574	collagen catabolic process	6.132648e-5
GO:0045324	late endosome to vacuole transport	6.253998e-5
GO:0071321	cellular response to cGMP	6.423204e-5
GO:0009125	nucleoside monophosphate catabolic process	6.424991e-5
GO:0030168	platelet activation	6.447302e-5
GO:0051971	positive regulation of transmission of nerve impulse	6.496633e-5
GO:0002700	regulation of production of molecular mediator of immune response	6.518452e-5
GO:0045059	positive thymic T cell selection	6.738709e-5
GO:0006887	exocytosis	6.812300e-5
GO:0007611	learning or memory	6.841436e-5
GO:0071229	cellular response to acid	6.874702e-5
GO:0043535	regulation of blood vessel endothelial cell migration	7.009862e-5
GO:0043367	CD4-positive, alpha-beta T cell differentiation	7.223748e-5
GO:0051053	negative regulation of DNA metabolic process	7.423877e-5
GO:0006682	galactosylceramide biosynthetic process	7.624630e-5
GO:0006811	ion transport	7.684406e-5
GO:0032320	positive regulation of Ras GTPase activity	8.002178e-5
GO:0048732	gland development	8.092114e-5
GO:0009743	response to carbohydrate stimulus	8.114602e-5
GO:0030862	positive regulation of polarized epithelial cell differentiation	8.151022e-5
GO:0050907	detection of chemical stimulus involved in sensory perception	8.163854e-5
GO:0051893	regulation of focal adhesion assembly	8.286746e-5
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	8.351928e-5
GO:0002886	regulation of myeloid leukocyte mediated immunity	8.359955e-5
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	8.366068e-5
GO:0046724	oxalic acid secretion	8.366068e-5
GO:0007275	multicellular organismal development	8.556967e-5
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	8.670010e-5
GO:0070417	cellular response to cold	8.844247e-5
GO:0001909	leukocyte mediated cytotoxicity	8.884832e-5
GO:0002673	regulation of acute inflammatory response	9.113329e-5
GO:0043353	enucleate erythrocyte differentiation	9.170681e-5
GO:0060341	regulation of cellular localization	9.254571e-5
GO:0060555	induction of necroptosis by extracellular signals	9.254800e-5
GO:0007155	cell adhesion	9.362782e-5
GO:0007596	blood coagulation	9.507383e-5
GO:0043462	regulation of ATPase activity	9.535178e-5
GO:0030889	negative regulation of B cell proliferation	9.548532e-5
GO:0050710	negative regulation of cytokine secretion	9.945464e-5
GO:0007202	activation of phospholipase C activity	1.034591e-4
GO:0014047	glutamate secretion	1.140485e-4
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.149047e-4
GO:0051549	positive regulation of keratinocyte migration	1.169166e-4
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	1.175426e-4
GO:0070305	response to cGMP	1.248232e-4
GO:0060627	regulation of vesicle-mediated transport	1.248414e-4
GO:0030888	regulation of B cell proliferation	1.257529e-4
GO:0048584	positive regulation of response to stimulus	1.266887e-4
GO:0022607	cellular component assembly	1.338573e-4
GO:0045684	positive regulation of epidermis development	1.349418e-4
GO:0042267	natural killer cell mediated cytotoxicity	1.350188e-4
GO:0035721	intraflagellar retrograde transport	1.355830e-4
GO:0016560	protein import into peroxisome matrix, docking	1.355830e-4
GO:0042035	regulation of cytokine biosynthetic process	1.363223e-4
GO:0051956	negative regulation of amino acid transport	1.378053e-4
GO:0045321	leukocyte activation	1.404611e-4
GO:0007599	hemostasis	1.413716e-4
GO:0002678	positive regulation of chronic inflammatory response	1.415720e-4
GO:0034763	negative regulation of transmembrane transport	1.420816e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.439843e-4
GO:2000379	positive regulation of reactive oxygen species metabolic process	1.449292e-4
GO:0001817	regulation of cytokine production	1.482041e-4
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.495126e-4
GO:0015816	glycine transport	1.565961e-4
GO:0032092	positive regulation of protein binding	1.572191e-4
GO:0032375	negative regulation of cholesterol transport	1.583800e-4
GO:0006733	oxidoreduction coenzyme metabolic process	1.621160e-4
GO:0045796	negative regulation of intestinal cholesterol absorption	1.682896e-4
GO:0010949	negative regulation of intestinal phytosterol absorption	1.682896e-4
GO:0006821	chloride transport	1.688784e-4
GO:0001957	intramembranous ossification	1.703088e-4
GO:0045069	regulation of viral genome replication	1.708594e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.721661e-4
GO:0032876	negative regulation of DNA endoreduplication	1.723679e-4
GO:0048739	cardiac muscle fiber development	1.758848e-4
GO:0009888	tissue development	1.766588e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	1.835753e-4
GO:0010594	regulation of endothelial cell migration	1.868627e-4
GO:0009749	response to glucose stimulus	1.889260e-4
GO:0071230	cellular response to amino acid stimulus	1.960427e-4
GO:0002676	regulation of chronic inflammatory response	1.991271e-4
GO:0003018	vascular process in circulatory system	2.022914e-4
GO:0030036	actin cytoskeleton organization	2.048427e-4
GO:0051292	nuclear pore complex assembly	2.052128e-4
GO:0044093	positive regulation of molecular function	2.080556e-4
GO:0010863	positive regulation of phospholipase C activity	2.107620e-4
GO:0051046	regulation of secretion	2.155224e-4
GO:0032890	regulation of organic acid transport	2.175386e-4
GO:0031915	positive regulation of synaptic plasticity	2.183102e-4
GO:0034614	cellular response to reactive oxygen species	2.209370e-4
GO:0051151	negative regulation of smooth muscle cell differentiation	2.215836e-4
GO:0035235	ionotropic glutamate receptor signaling pathway	2.244612e-4
GO:0030335	positive regulation of cell migration	2.252659e-4
GO:0001812	positive regulation of type I hypersensitivity	2.298543e-4
GO:0008624	induction of apoptosis by extracellular signals	2.300457e-4
GO:0050790	regulation of catalytic activity	2.310353e-4
GO:0007050	cell cycle arrest	2.345686e-4
GO:0030004	cellular monovalent inorganic cation homeostasis	2.362121e-4
GO:0010350	cellular response to magnesium starvation	2.365168e-4
GO:0048534	hemopoietic or lymphoid organ development	2.392141e-4
GO:0030029	actin filament-based process	2.435623e-4
GO:0048731	system development	2.498506e-4
GO:0021987	cerebral cortex development	2.526075e-4
GO:0071636	positive regulation of transforming growth factor beta production	2.529322e-4
GO:0034205	beta-amyloid formation	2.535320e-4
GO:0034284	response to monosaccharide stimulus	2.556827e-4
GO:0008625	induction of apoptosis via death domain receptors	2.622914e-4
GO:2000147	positive regulation of cell motility	2.629831e-4
GO:0050806	positive regulation of synaptic transmission	2.634425e-4
GO:0007131	reciprocal meiotic recombination	2.646485e-4
GO:0007527	adult somatic muscle development	2.686851e-4
GO:0051240	positive regulation of multicellular organismal process	2.730722e-4
GO:0007320	insemination	2.731728e-4
GO:0040017	positive regulation of locomotion	2.771302e-4
GO:0048518	positive regulation of biological process	2.787383e-4
GO:0042462	eye photoreceptor cell development	2.856556e-4
GO:0007098	centrosome cycle	2.890868e-4
GO:0032908	regulation of transforming growth factor beta1 production	2.906347e-4
GO:0010595	positive regulation of endothelial cell migration	2.946372e-4
GO:0009746	response to hexose stimulus	3.063343e-4
GO:0070507	regulation of microtubule cytoskeleton organization	3.132423e-4
GO:0051098	regulation of binding	3.171256e-4
GO:0010954	positive regulation of protein processing	3.226312e-4
GO:0032879	regulation of localization	3.282631e-4
GO:0050878	regulation of body fluid levels	3.326065e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.354070e-4
GO:0070845	polyubiquitinated misfolded protein transport	3.406275e-4
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	3.431164e-4
GO:0040001	establishment of mitotic spindle localization	3.450050e-4
GO:0042461	photoreceptor cell development	3.486656e-4
GO:0000132	establishment of mitotic spindle orientation	3.528695e-4
GO:0043932	ossification involved in bone remodeling	3.550570e-4
GO:0008306	associative learning	3.597626e-4
GO:0033864	positive regulation of NAD(P)H oxidase activity	3.663017e-4
GO:0050890	cognition	3.685367e-4
GO:0006111	regulation of gluconeogenesis	3.737399e-4
GO:0017158	regulation of calcium ion-dependent exocytosis	3.774612e-4
GO:0050709	negative regulation of protein secretion	3.784125e-4
GO:0022600	digestive system process	3.820264e-4
GO:0003051	angiotensin-mediated drinking behavior	3.901337e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	4.020274e-4
GO:0007174	epidermal growth factor catabolic process	4.085200e-4
GO:0065008	regulation of biological quality	4.096864e-4
GO:0009612	response to mechanical stimulus	4.144804e-4
GO:0042438	melanin biosynthetic process	4.176455e-4
GO:0046549	retinal cone cell development	4.256440e-4
GO:0030449	regulation of complement activation	4.275779e-4
GO:0050906	detection of stimulus involved in sensory perception	4.277091e-4
GO:0007250	activation of NF-kappaB-inducing kinase activity	4.435263e-4
GO:0042036	negative regulation of cytokine biosynthetic process	4.491307e-4
GO:0034014	response to triglyceride	4.584002e-4
GO:0032886	regulation of microtubule-based process	4.647088e-4
GO:0051297	centrosome organization	4.724123e-4
GO:0046325	negative regulation of glucose import	4.728171e-4
GO:0097120	receptor localization to synapse	4.817412e-4
GO:0072578	neurotransmitter-gated ion channel clustering	4.817412e-4
GO:0002282	microglial cell activation involved in immune response	4.817412e-4
GO:0030100	regulation of endocytosis	4.867968e-4
GO:0007126	meiosis	4.883327e-4
GO:0006621	protein retention in ER lumen	4.967647e-4
GO:0046599	regulation of centriole replication	5.005465e-4
GO:0009605	response to external stimulus	5.011322e-4
GO:0009253	peptidoglycan catabolic process	5.077764e-4
GO:0050863	regulation of T cell activation	5.093911e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	5.098631e-4
GO:0071460	cellular response to cell-matrix adhesion	5.104118e-4
GO:0046687	response to chromate	5.104118e-4
GO:0033986	response to methanol	5.104118e-4
GO:0052509	positive regulation by symbiont of host defense response	5.125573e-4
GO:0048522	positive regulation of cellular process	5.228388e-4
GO:0007127	meiosis I	5.250013e-4
GO:0048489	synaptic vesicle transport	5.266633e-4
GO:2000679	positive regulation of transcription regulatory region DNA binding	5.268837e-4
GO:0032680	regulation of tumor necrosis factor production	5.277537e-4
GO:0019221	cytokine-mediated signaling pathway	5.288598e-4
GO:0016049	cell growth	5.316430e-4
GO:0043117	positive regulation of vascular permeability	5.493893e-4
GO:0050864	regulation of B cell activation	5.569197e-4
GO:0042938	dipeptide transport	5.573433e-4
GO:0043269	regulation of ion transport	5.581665e-4
GO:0042098	T cell proliferation	5.636974e-4
GO:0031641	regulation of myelination	5.648024e-4
GO:2000739	regulation of mesenchymal stem cell differentiation	5.662775e-4
GO:0044130	negative regulation of growth of symbiont in host	5.890802e-4
GO:0045104	intermediate filament cytoskeleton organization	5.939632e-4
GO:2001021	negative regulation of response to DNA damage stimulus	5.984679e-4
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	6.111150e-4
GO:0051685	maintenance of ER location	6.119373e-4
GO:0042542	response to hydrogen peroxide	6.171652e-4
GO:0071495	cellular response to endogenous stimulus	6.199087e-4
GO:0031581	hemidesmosome assembly	6.341711e-4
GO:0032252	secretory granule localization	6.507410e-4
GO:0010951	negative regulation of endopeptidase activity	6.508611e-4
GO:2000617	positive regulation of histone H3-K9 acetylation	6.515658e-4
GO:2000620	positive regulation of histone H4-K16 acetylation	6.515658e-4
GO:0070512	positive regulation of histone H4-K20 methylation	6.515658e-4
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	6.515658e-4
GO:0007586	digestion	6.704579e-4
GO:0006959	humoral immune response	6.757091e-4
GO:0032845	negative regulation of homeostatic process	6.786974e-4
GO:0042743	hydrogen peroxide metabolic process	6.793820e-4
GO:0043277	apoptotic cell clearance	6.887445e-4
GO:0010535	positive regulation of activation of JAK2 kinase activity	6.977045e-4
GO:0051298	centrosome duplication	6.997646e-4
GO:0007522	visceral muscle development	7.017252e-4
GO:0080134	regulation of response to stress	7.049753e-4
GO:0042982	amyloid precursor protein metabolic process	7.123995e-4
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	7.208484e-4
GO:0010560	positive regulation of glycoprotein biosynthetic process	7.209464e-4
GO:0060040	retinal bipolar neuron differentiation	7.263066e-4
GO:0023051	regulation of signaling	7.508473e-4
GO:0051272	positive regulation of cellular component movement	7.582854e-4
GO:0045760	positive regulation of action potential	7.598316e-4
GO:0000302	response to reactive oxygen species	7.605195e-4
GO:0032101	regulation of response to external stimulus	7.613388e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	7.744805e-4
GO:0010518	positive regulation of phospholipase activity	7.765431e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016579	protein deubiquitination	9.873670e-17
GO:0070646	protein modification by small protein removal	1.849014e-12
GO:0007154	cell communication	1.954968e-11
GO:0023052	signaling	5.835738e-11
GO:0002376	immune system process	5.872003e-11
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	1.686132e-10
GO:0007166	cell surface receptor linked signaling pathway	1.972984e-10
GO:0065008	regulation of biological quality	3.748963e-10
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	6.743788e-10
GO:0002521	leukocyte differentiation	9.803970e-10
GO:0055072	iron ion homeostasis	2.123397e-9
GO:0007165	signal transduction	2.263863e-9
GO:0006826	iron ion transport	3.096817e-9
GO:0030097	hemopoiesis	4.926917e-9
GO:0001775	cell activation	6.480125e-9
GO:0010627	regulation of intracellular protein kinase cascade	6.828859e-9
GO:0048534	hemopoietic or lymphoid organ development	7.688153e-9
GO:0060457	negative regulation of digestive system process	9.309451e-9
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	1.688561e-8
GO:0002520	immune system development	1.881500e-8
GO:0043620	regulation of DNA-dependent transcription in response to stress	1.961551e-8
GO:0014012	peripheral nervous system axon regeneration	2.385304e-8
GO:0046427	positive regulation of JAK-STAT cascade	2.626559e-8
GO:0050896	response to stimulus	2.936177e-8
GO:0010740	positive regulation of intracellular protein kinase cascade	3.451437e-8
GO:0009611	response to wounding	3.582585e-8
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	5.268621e-8
GO:0051385	response to mineralocorticoid stimulus	5.553823e-8
GO:0046425	regulation of JAK-STAT cascade	6.061256e-8
GO:0006950	response to stress	9.555051e-8
GO:0055080	cation homeostasis	1.004527e-7
GO:0042110	T cell activation	1.065711e-7
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	1.143718e-7
GO:0006879	cellular iron ion homeostasis	1.260836e-7
GO:0045796	negative regulation of intestinal cholesterol absorption	1.303958e-7
GO:0010949	negative regulation of intestinal phytosterol absorption	1.303958e-7
GO:0032946	positive regulation of mononuclear cell proliferation	1.336751e-7
GO:0030217	T cell differentiation	1.367422e-7
GO:0045321	leukocyte activation	1.607891e-7
GO:0070665	positive regulation of leukocyte proliferation	1.675427e-7
GO:0055065	metal ion homeostasis	2.191658e-7
GO:0048878	chemical homeostasis	2.442867e-7
GO:0051412	response to corticosterone stimulus	2.756304e-7
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.126477e-7
GO:0050671	positive regulation of lymphocyte proliferation	3.358793e-7
GO:0006811	ion transport	4.240414e-7
GO:0030098	lymphocyte differentiation	4.455332e-7
GO:0030104	water homeostasis	5.624734e-7
GO:0051716	cellular response to stimulus	8.869627e-7
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	9.710315e-7
GO:0042102	positive regulation of T cell proliferation	1.031435e-6
GO:0046649	lymphocyte activation	1.378830e-6
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	1.711680e-6
GO:0061308	cardiac neural crest cell development involved in heart development	1.819353e-6
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.911340e-6
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	1.982053e-6
GO:0006508	proteolysis	2.434389e-6
GO:0065007	biological regulation	2.652102e-6
GO:0009185	ribonucleoside diphosphate metabolic process	3.211927e-6
GO:0042493	response to drug	3.213142e-6
GO:0051384	response to glucocorticoid stimulus	3.246284e-6
GO:0042592	homeostatic process	3.463325e-6
GO:0048731	system development	4.120769e-6
GO:0035904	aorta development	4.743681e-6
GO:0060442	branching involved in prostate gland morphogenesis	5.176086e-6
GO:0045329	carnitine biosynthetic process	5.497734e-6
GO:0003008	system process	5.995478e-6
GO:0050801	ion homeostasis	6.110525e-6
GO:0007007	inner mitochondrial membrane organization	6.553934e-6
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	7.459686e-6
GO:0009088	threonine biosynthetic process	7.494117e-6
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	7.586062e-6
GO:0003209	cardiac atrium morphogenesis	9.100340e-6
GO:0014850	response to muscle activity	9.212798e-6
GO:0006875	cellular metal ion homeostasis	9.339309e-6
GO:0034103	regulation of tissue remodeling	9.640400e-6
GO:0003230	cardiac atrium development	1.058016e-5
GO:0035964	COPI-coated vesicle budding	1.071223e-5
GO:0048513	organ development	1.276028e-5
GO:0030003	cellular cation homeostasis	1.325826e-5
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	1.327564e-5
GO:0009967	positive regulation of signal transduction	1.347378e-5
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.397955e-5
GO:0031017	exocrine pancreas development	1.502117e-5
GO:0019725	cellular homeostasis	1.503410e-5
GO:0006812	cation transport	1.518912e-5
GO:0007588	excretion	1.544007e-5
GO:0007258	JUN phosphorylation	1.621493e-5
GO:0006029	proteoglycan metabolic process	1.856508e-5
GO:0006954	inflammatory response	1.857363e-5
GO:0002407	dendritic cell chemotaxis	2.250672e-5
GO:0055082	cellular chemical homeostasis	2.339088e-5
GO:0046850	regulation of bone remodeling	2.350503e-5
GO:0014732	skeletal muscle atrophy	2.434792e-5
GO:0061307	cardiac neural crest cell differentiation involved in heart development	2.475122e-5
GO:0071731	response to nitric oxide	2.564505e-5
GO:0048193	Golgi vesicle transport	2.949583e-5
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	2.970197e-5
GO:0006955	immune response	3.002528e-5
GO:0044093	positive regulation of molecular function	3.082311e-5
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	3.120698e-5
GO:0015876	acetyl-CoA transport	3.166450e-5
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	3.324523e-5
GO:0045085	negative regulation of interleukin-2 biosynthetic process	3.421471e-5
GO:0048678	response to axon injury	3.462077e-5
GO:0009415	response to water	3.577882e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	3.578094e-5
GO:0000045	autophagic vacuole assembly	3.772015e-5
GO:0032501	multicellular organismal process	4.261059e-5
GO:0010994	free ubiquitin chain polymerization	4.520408e-5
GO:0043270	positive regulation of ion transport	4.722290e-5
GO:0042036	negative regulation of cytokine biosynthetic process	4.950089e-5
GO:0006566	threonine metabolic process	5.206015e-5
GO:0060282	positive regulation of oocyte development	6.090698e-5
GO:0060281	regulation of oocyte development	6.090698e-5
GO:0045725	positive regulation of glycogen biosynthetic process	6.154400e-5
GO:0015755	fructose transport	6.246811e-5
GO:0007167	enzyme linked receptor protein signaling pathway	6.775092e-5
GO:0044057	regulation of system process	6.787550e-5
GO:0045821	positive regulation of glycolysis	6.924803e-5
GO:0001661	conditioned taste aversion	6.925102e-5
GO:0006914	autophagy	7.157817e-5
GO:0070663	regulation of leukocyte proliferation	7.664170e-5
GO:0010765	positive regulation of sodium ion transport	7.773632e-5
GO:0014904	myotube cell development	7.929119e-5
GO:0035909	aorta morphogenesis	7.996835e-5
GO:0042221	response to chemical stimulus	8.285543e-5
GO:0048856	anatomical structure development	8.613009e-5
GO:0065009	regulation of molecular function	8.823345e-5
GO:0050789	regulation of biological process	8.894571e-5
GO:0030001	metal ion transport	8.973302e-5
GO:0010633	negative regulation of epithelial cell migration	8.998462e-5
GO:0009743	response to carbohydrate stimulus	9.026841e-5
GO:0014911	positive regulation of smooth muscle cell migration	9.138536e-5
GO:0045937	positive regulation of phosphate metabolic process	9.521186e-5
GO:0042035	regulation of cytokine biosynthetic process	9.855498e-5
GO:0045190	isotype switching	1.013952e-4
GO:0042327	positive regulation of phosphorylation	1.041601e-4
GO:0006172	ADP biosynthetic process	1.067728e-4
GO:0015711	organic anion transport	1.139733e-4
GO:0090257	regulation of muscle system process	1.161112e-4
GO:0032944	regulation of mononuclear cell proliferation	1.174379e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.189961e-4
GO:0006873	cellular ion homeostasis	1.296328e-4
GO:0055074	calcium ion homeostasis	1.314116e-4
GO:0032789	unsaturated monocarboxylic acid metabolic process	1.322298e-4
GO:0032788	saturated monocarboxylic acid metabolic process	1.322298e-4
GO:0007275	multicellular organismal development	1.366926e-4
GO:0031960	response to corticosteroid stimulus	1.369195e-4
GO:2000249	regulation of actin cytoskeleton reorganization	1.403966e-4
GO:0060326	cell chemotaxis	1.404773e-4
GO:0045651	positive regulation of macrophage differentiation	1.426488e-4
GO:0010811	positive regulation of cell-substrate adhesion	1.457829e-4
GO:0045058	T cell selection	1.499890e-4
GO:0002312	B cell activation involved in immune response	1.531776e-4
GO:0043067	regulation of programmed cell death	1.539665e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.555606e-4
GO:0032535	regulation of cellular component size	1.646131e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	1.649255e-4
GO:0042594	response to starvation	1.736324e-4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.743627e-4
GO:0009651	response to salt stress	1.753598e-4
GO:0007625	grooming behavior	1.779632e-4
GO:0031103	axon regeneration	1.906933e-4
GO:0032092	positive regulation of protein binding	1.930104e-4
GO:0042981	regulation of apoptosis	1.933271e-4
GO:0006952	defense response	1.945462e-4
GO:0003091	renal water homeostasis	1.974283e-4
GO:0031295	T cell costimulation	1.985252e-4
GO:0010960	magnesium ion homeostasis	1.987037e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.994786e-4
GO:0003278	apoptosis involved in heart morphogenesis	2.032169e-4
GO:2000353	positive regulation of endothelial cell apoptosis	2.039552e-4
GO:0009100	glycoprotein metabolic process	2.047899e-4
GO:0023056	positive regulation of signaling	2.075207e-4
GO:0031102	neuron projection regeneration	2.100886e-4
GO:0055005	ventricular cardiac myofibril development	2.103295e-4
GO:0050670	regulation of lymphocyte proliferation	2.154522e-4
GO:0030850	prostate gland development	2.155493e-4
GO:0045124	regulation of bone resorption	2.171545e-4
GO:0014889	muscle atrophy	2.254350e-4
GO:0009069	serine family amino acid metabolic process	2.304007e-4
GO:0010646	regulation of cell communication	2.398751e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	2.423882e-4
GO:0010647	positive regulation of cell communication	2.424541e-4
GO:0003347	epicardial cell to mesenchymal cell transition	2.450756e-4
GO:0031016	pancreas development	2.457736e-4
GO:0006937	regulation of muscle contraction	2.564160e-4
GO:0030168	platelet activation	2.687103e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	2.697694e-4
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	2.704646e-4
GO:0034605	cellular response to heat	2.729038e-4
GO:0000238	zygotene	2.833740e-4
GO:0051247	positive regulation of protein metabolic process	2.980823e-4
GO:0055085	transmembrane transport	2.987037e-4
GO:0035587	purinergic receptor signaling pathway	3.093588e-4
GO:0010759	positive regulation of macrophage chemotaxis	3.191534e-4
GO:0042129	regulation of T cell proliferation	3.230276e-4
GO:0060413	atrial septum morphogenesis	3.245391e-4
GO:0060512	prostate gland morphogenesis	3.446125e-4
GO:0009414	response to water deprivation	3.845199e-4
GO:0002366	leukocyte activation involved in immune response	3.993125e-4
GO:0030099	myeloid cell differentiation	4.353669e-4
GO:2000271	positive regulation of fibroblast apoptosis	4.377983e-4
GO:2000270	negative regulation of fibroblast apoptosis	4.377983e-4
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	4.377983e-4
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	4.377983e-4
GO:0045062	extrathymic T cell selection	4.443918e-4
GO:0090186	regulation of pancreatic juice secretion	4.453696e-4
GO:0090182	regulation of secretion of lysosomal enzymes	4.453696e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	4.453696e-4
GO:0048550	negative regulation of pinocytosis	4.453696e-4
GO:0030595	leukocyte chemotaxis	4.469096e-4
GO:0009134	nucleoside diphosphate catabolic process	4.511867e-4
GO:0048584	positive regulation of response to stimulus	4.588477e-4
GO:0010632	regulation of epithelial cell migration	4.598358e-4
GO:0070875	positive regulation of glycogen metabolic process	4.631733e-4
GO:0008284	positive regulation of cell proliferation	4.720442e-4
GO:0009628	response to abiotic stimulus	4.744819e-4
GO:2000522	positive regulation of immunological synapse formation	4.842084e-4
GO:0010033	response to organic substance	4.854748e-4
GO:0032270	positive regulation of cellular protein metabolic process	4.965894e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	5.015981e-4
GO:0009071	serine family amino acid catabolic process	5.052909e-4
GO:0035588	G-protein coupled purinergic receptor signaling pathway	5.101713e-4
GO:0006487	protein N-linked glycosylation	5.129209e-4
GO:0051179	localization	5.160272e-4
GO:0050852	T cell receptor signaling pathway	5.268349e-4
GO:0003283	atrial septum development	5.415400e-4
GO:0048096	chromatin-mediated maintenance of transcription	5.439931e-4
GO:0050851	antigen receptor-mediated signaling pathway	5.600510e-4
GO:0071305	cellular response to vitamin D	5.677899e-4
GO:2000833	positive regulation of steroid hormone secretion	5.868845e-4
GO:0070647	protein modification by small protein conjugation or removal	5.957915e-4
GO:0070228	regulation of lymphocyte apoptosis	5.972211e-4
GO:0010951	negative regulation of endopeptidase activity	6.195391e-4
GO:0006704	glucocorticoid biosynthetic process	6.324369e-4
GO:0008206	bile acid metabolic process	6.494617e-4
GO:0006816	calcium ion transport	6.761471e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	6.820007e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	6.820007e-4
GO:0034341	response to interferon-gamma	6.900240e-4
GO:0060736	prostate gland growth	6.955386e-4
GO:0018149	peptide cross-linking	7.134714e-4
GO:0002028	regulation of sodium ion transport	7.134714e-4
GO:0070234	positive regulation of T cell apoptosis	7.337123e-4
GO:0003289	atrial septum primum morphogenesis	7.529237e-4
GO:0048548	regulation of pinocytosis	7.670600e-4
GO:0021558	trochlear nerve development	7.670600e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	7.721048e-4
GO:0009966	regulation of signal transduction	7.833521e-4
GO:0016236	macroautophagy	8.013472e-4
GO:0060740	prostate gland epithelium morphogenesis	8.158217e-4
GO:0003012	muscle system process	8.181048e-4
GO:0043248	proteasome assembly	8.264967e-4
GO:0046631	alpha-beta T cell activation	8.580046e-4
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	8.594403e-4
GO:0071380	cellular response to prostaglandin E stimulus	8.594403e-4
GO:0030521	androgen receptor signaling pathway	8.863159e-4
GO:0000245	spliceosome assembly	8.863159e-4
GO:0030890	positive regulation of B cell proliferation	9.033710e-4
GO:0072507	divalent inorganic cation homeostasis	9.068907e-4
GO:0045082	positive regulation of interleukin-10 biosynthetic process	9.122167e-4
GO:0009191	ribonucleoside diphosphate catabolic process	9.141843e-4
GO:0035335	peptidyl-tyrosine dephosphorylation	9.210083e-4
GO:0031399	regulation of protein modification process	9.326346e-4
GO:0050870	positive regulation of T cell activation	9.398792e-4
GO:0010766	negative regulation of sodium ion transport	9.629621e-4
GO:0051480	cytosolic calcium ion homeostasis	9.652835e-4
GO:0010941	regulation of cell death	9.672788e-4
GO:0042438	melanin biosynthetic process	9.901001e-4
GO:0009267	cellular response to starvation	1.008823e-3
GO:0035630	bone mineralization involved in bone maturation	1.010176e-3
GO:0034695	response to prostaglandin E stimulus	1.020090e-3
GO:0046626	regulation of insulin receptor signaling pathway	1.020793e-3
GO:0060412	ventricular septum morphogenesis	1.032182e-3
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	1.058001e-3
GO:0023051	regulation of signaling	1.064631e-3
GO:0003009	skeletal muscle contraction	1.070136e-3
GO:0009749	response to glucose stimulus	1.071452e-3
GO:0048250	mitochondrial iron ion transport	1.122511e-3
GO:0009437	carnitine metabolic process	1.150084e-3
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.155738e-3
GO:0051182	coenzyme transport	1.160286e-3
GO:0051639	actin filament network formation	1.165832e-3
GO:0010232	vascular transport	1.165832e-3
GO:0051541	elastin metabolic process	1.204241e-3
GO:0043088	regulation of Cdc42 GTPase activity	1.212439e-3
GO:0003281	ventricular septum development	1.234060e-3
GO:0009719	response to endogenous stimulus	1.252720e-3
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	1.301270e-3
GO:0007031	peroxisome organization	1.302978e-3
GO:0070972	protein localization in endoplasmic reticulum	1.308306e-3
GO:0032271	regulation of protein polymerization	1.316983e-3
GO:0042325	regulation of phosphorylation	1.352407e-3
GO:0006750	glutathione biosynthetic process	1.358935e-3
GO:0010970	microtubule-based transport	1.407246e-3
GO:0030913	paranodal junction assembly	1.420752e-3
GO:0051915	induction of synaptic plasticity by chemical substance	1.437111e-3
GO:0031018	endocrine pancreas development	1.453427e-3
GO:0070977	bone maturation	1.479554e-3
GO:0001833	inner cell mass cell proliferation	1.489243e-3
GO:0045103	intermediate filament-based process	1.496618e-3
GO:0043065	positive regulation of apoptosis	1.502496e-3
GO:0048545	response to steroid hormone stimulus	1.502938e-3
GO:0030166	proteoglycan biosynthetic process	1.503018e-3
GO:0033574	response to testosterone stimulus	1.554795e-3
GO:0032846	positive regulation of homeostatic process	1.555019e-3
GO:0006582	melanin metabolic process	1.557290e-3
GO:0071460	cellular response to cell-matrix adhesion	1.564020e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	1.564020e-3
GO:0045409	negative regulation of interleukin-6 biosynthetic process	1.584833e-3
GO:0034284	response to monosaccharide stimulus	1.621136e-3
GO:0010758	regulation of macrophage chemotaxis	1.621947e-3
GO:0050865	regulation of cell activation	1.629570e-3
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	1.630005e-3
GO:0061325	cell proliferation involved in outflow tract morphogenesis	1.630005e-3
GO:0070245	positive regulation of thymocyte apoptosis	1.634368e-3
GO:0006621	protein retention in ER lumen	1.636620e-3
GO:0009314	response to radiation	1.676522e-3
GO:0031401	positive regulation of protein modification process	1.681321e-3
GO:0006790	sulfur compound metabolic process	1.688519e-3
GO:0002694	regulation of leukocyte activation	1.695528e-3
GO:0010907	positive regulation of glucose metabolic process	1.713976e-3
GO:0071474	cellular hyperosmotic response	1.723904e-3
GO:0046487	glyoxylate metabolic process	1.723904e-3
GO:0048679	regulation of axon regeneration	1.734617e-3
GO:0046651	lymphocyte proliferation	1.758968e-3
GO:0051409	response to nitrosative stress	1.765142e-3
GO:0072355	histone H3-T3 phosphorylation	1.779708e-3
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.784058e-3
GO:0050867	positive regulation of cell activation	1.791393e-3
GO:0006376	mRNA splice site selection	1.794630e-3
GO:0048813	dendrite morphogenesis	1.796819e-3
GO:2000978	negative regulation of forebrain neuron differentiation	1.811160e-3
GO:2000227	negative regulation of pancreatic A cell differentiation	1.811160e-3
GO:0046331	lateral inhibition	1.811160e-3
GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	1.811160e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	1.833337e-3
GO:0035910	ascending aorta morphogenesis	1.833337e-3
GO:0010038	response to metal ion	1.895951e-3
GO:0006536	glutamate metabolic process	1.905322e-3
GO:0071675	regulation of mononuclear cell migration	1.908150e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.912045e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	1.942379e-3
GO:0010739	positive regulation of protein kinase A signaling cascade	1.962374e-3
GO:2000831	regulation of steroid hormone secretion	1.962374e-3
GO:0019220	regulation of phosphate metabolic process	1.977314e-3
GO:0006548	histidine catabolic process	2.056231e-3
GO:0043068	positive regulation of programmed cell death	2.110301e-3
GO:0043043	peptide biosynthetic process	2.121309e-3
GO:0060741	prostate gland stromal morphogenesis	2.126798e-3
GO:0071622	regulation of granulocyte chemotaxis	2.155550e-3
GO:0002903	negative regulation of B cell apoptosis	2.155550e-3
GO:0010035	response to inorganic substance	2.156098e-3
GO:0005978	glycogen biosynthetic process	2.162578e-3
GO:0031113	regulation of microtubule polymerization	2.170155e-3
GO:0005979	regulation of glycogen biosynthetic process	2.174714e-3
GO:0043252	sodium-independent organic anion transport	2.196452e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	2.196452e-3
GO:0030299	intestinal cholesterol absorption	2.284270e-3
GO:0042098	T cell proliferation	2.304048e-3
GO:0050790	regulation of catalytic activity	2.346836e-3
GO:0045348	positive regulation of MHC class II biosynthetic process	2.348757e-3
GO:0002246	wound healing involved in inflammatory response	2.352455e-3
GO:0035019	somatic stem cell maintenance	2.395787e-3
GO:0009629	response to gravity	2.432798e-3
GO:0070230	positive regulation of lymphocyte apoptosis	2.434581e-3
GO:0007204	elevation of cytosolic calcium ion concentration	2.494803e-3
GO:0048638	regulation of developmental growth	2.515311e-3
GO:0031650	regulation of heat generation	2.535230e-3
GO:0010942	positive regulation of cell death	2.566612e-3
GO:0001866	NK T cell proliferation	2.572179e-3
GO:0071842	cellular component organization at cellular level	2.601214e-3
GO:0034214	protein hexamerization	2.607831e-3
GO:0045061	thymic T cell selection	2.639396e-3
GO:0002429	immune response-activating cell surface receptor signaling pathway	2.654799e-3
GO:0048199	vesicle targeting, to, from or within Golgi	2.656143e-3
GO:0002906	negative regulation of mature B cell apoptosis	2.670438e-3
GO:0010501	RNA secondary structure unwinding	2.672141e-3
GO:0007181	transforming growth factor beta receptor complex assembly	2.672141e-3
GO:0010466	negative regulation of peptidase activity	2.694128e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	2.698182e-3
GO:0046579	positive regulation of Ras protein signal transduction	2.701719e-3
GO:0009607	response to biotic stimulus	2.706512e-3
GO:0007596	blood coagulation	2.721987e-3
GO:0009746	response to hexose stimulus	2.724023e-3
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	2.724610e-3
GO:0051246	regulation of protein metabolic process	2.751128e-3
GO:0009992	cellular water homeostasis	2.785898e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	2.785898e-3
GO:0072321	chaperone-mediated protein transport	2.792416e-3
GO:0051707	response to other organism	2.837046e-3
GO:0050877	neurological system process	2.885150e-3
GO:0045780	positive regulation of bone resorption	2.907102e-3
GO:0045064	T-helper 2 cell differentiation	2.946926e-3
GO:0045988	negative regulation of striated muscle contraction	2.962090e-3
GO:0060411	cardiac septum morphogenesis	2.975570e-3
GO:0007599	hemostasis	2.992567e-3
GO:2000107	negative regulation of leukocyte apoptosis	3.003926e-3
GO:0032844	regulation of homeostatic process	3.104400e-3
GO:0009725	response to hormone stimulus	3.165997e-3
GO:0040012	regulation of locomotion	3.167864e-3
GO:0033085	negative regulation of T cell differentiation in thymus	3.179075e-3
GO:0010724	regulation of definitive erythrocyte differentiation	3.189359e-3
GO:0071496	cellular response to external stimulus	3.190836e-3
GO:0071402	cellular response to lipoprotein particle stimulus	3.204234e-3
GO:0043269	regulation of ion transport	3.242497e-3
GO:0010959	regulation of metal ion transport	3.271405e-3
GO:0050794	regulation of cellular process	3.294215e-3
GO:0043383	negative T cell selection	3.352038e-3
GO:0034392	negative regulation of smooth muscle cell apoptosis	3.361525e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	3.367512e-3
GO:0045671	negative regulation of osteoclast differentiation	3.398051e-3
GO:0043085	positive regulation of catalytic activity	3.398895e-3
GO:0072595	maintenance of protein localization to organelle	3.402675e-3
GO:0051081	nuclear envelope disassembly	3.464640e-3
GO:0015911	plasma membrane long-chain fatty acid transport	3.464640e-3
GO:0009201	ribonucleoside triphosphate biosynthetic process	3.472505e-3
GO:0001934	positive regulation of protein phosphorylation	3.493126e-3
GO:0006874	cellular calcium ion homeostasis	3.534698e-3
GO:0003206	cardiac chamber morphogenesis	3.588551e-3
GO:0046627	negative regulation of insulin receptor signaling pathway	3.592101e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	3.693635e-3
GO:0000147	actin cortical patch assembly	3.726269e-3
GO:0071392	cellular response to estradiol stimulus	3.735051e-3
GO:0048505	regulation of timing of cell differentiation	3.762722e-3
GO:0048676	axon extension involved in development	3.762722e-3
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	3.816170e-3
GO:0019827	stem cell maintenance	3.831137e-3
GO:0002285	lymphocyte activation involved in immune response	3.834970e-3
GO:0030432	peristalsis	3.913597e-3
GO:0001819	positive regulation of cytokine production	3.918984e-3
GO:0060973	cell migration involved in heart development	3.944518e-3
GO:0052548	regulation of endopeptidase activity	3.945807e-3
GO:0032943	mononuclear cell proliferation	4.021237e-3
GO:0001501	skeletal system development	4.051486e-3
GO:0032663	regulation of interleukin-2 production	4.152229e-3
GO:0070914	UV-damage excision repair	4.157456e-3
GO:0008582	regulation of synaptic growth at neuromuscular junction	4.157456e-3
GO:0010224	response to UV-B	4.176379e-3
GO:0000041	transition metal ion transport	4.236183e-3
GO:0006547	histidine metabolic process	4.239105e-3
GO:0070661	leukocyte proliferation	4.240050e-3
GO:0032878	regulation of establishment or maintenance of cell polarity	4.243786e-3
GO:0046034	ATP metabolic process	4.260682e-3
GO:0009416	response to light stimulus	4.260682e-3
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	4.275020e-3
GO:0048305	immunoglobulin secretion	4.280136e-3
GO:0046341	CDP-diacylglycerol metabolic process	4.316953e-3
GO:0097026	dendritic cell dendrite assembly	4.316953e-3
GO:0032633	interleukin-4 production	4.316953e-3
GO:0038003	opioid receptor signaling pathway	4.316953e-3
GO:0001865	NK T cell differentiation	4.316953e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	4.318997e-3
GO:0006168	adenine salvage	4.327781e-3
GO:0048840	otolith development	4.348339e-3
GO:0055119	relaxation of cardiac muscle	4.348339e-3
GO:0001932	regulation of protein phosphorylation	4.352891e-3
GO:0048478	replication fork protection	4.370708e-3
GO:0034755	iron ion transmembrane transport	4.479207e-3
GO:0002757	immune response-activating signal transduction	4.507260e-3
GO:0070307	lens fiber cell development	4.546205e-3
GO:0002577	regulation of antigen processing and presentation	4.588562e-3
GO:0019748	secondary metabolic process	4.633392e-3
GO:0032496	response to lipopolysaccharide	4.655492e-3
GO:0006544	glycine metabolic process	4.661963e-3
GO:0050862	positive regulation of T cell receptor signaling pathway	4.687389e-3
GO:0007342	fusion of sperm to egg plasma membrane	4.687389e-3
GO:0046632	alpha-beta T cell differentiation	4.693468e-3
GO:0001832	blastocyst growth	4.746645e-3
GO:0060088	auditory receptor cell stereocilium organization	4.752500e-3
GO:0051181	cofactor transport	4.752500e-3
GO:0007033	vacuole organization	4.761450e-3
GO:0003231	cardiac ventricle development	4.776331e-3
GO:0045815	positive regulation of gene expression, epigenetic	4.863127e-3
GO:0030212	hyaluronan metabolic process	4.863127e-3
GO:0050863	regulation of T cell activation	4.884063e-3
GO:0006754	ATP biosynthetic process	4.989459e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	5.016262e-3
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	5.051909e-3
GO:0048771	tissue remodeling	5.096870e-3
GO:0047497	mitochondrion transport along microtubule	5.135092e-3
GO:0003407	neural retina development	5.137078e-3
GO:0007015	actin filament organization	5.144909e-3
GO:0006953	acute-phase response	5.177453e-3
GO:0048015	phosphatidylinositol-mediated signaling	5.177453e-3
GO:0090066	regulation of anatomical structure size	5.221694e-3
GO:0001743	optic placode formation	5.224828e-3
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	5.233589e-3
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	5.292020e-3
GO:0043403	skeletal muscle tissue regeneration	5.292841e-3
GO:0071732	cellular response to nitric oxide	5.300249e-3
GO:0002328	pro-B cell differentiation	5.300249e-3
GO:0045123	cellular extravasation	5.343590e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	5.424081e-3
GO:0002369	T cell cytokine production	5.424081e-3
GO:0060013	righting reflex	5.426375e-3
GO:0060401	cytosolic calcium ion transport	5.475399e-3
GO:2000106	regulation of leukocyte apoptosis	5.489107e-3