FF:11877-125C5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004834 | ||
| | |accession_numbers=CAGE;DRX008145;DRR009017;DRZ000442;DRZ001827;DRZ011792;DRZ013177 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000634,FF:0011105 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.94!874.94!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.74!552.36!SPI1;;chr7:115670804..115670825,-!p1@TFEC!2.52!332.95!TFEC;;chr12:54778471..54778528,-!p1@ZNF385A!2.37!233.88!ZNF385A;;chr21:34442439..34442455,+!p1@OLIG1!2.24!171.93!OLIG1;;chr10:64576105..64576133,-!p1@EGR2!2.07!230.61!EGR2;;chr11:47399947..47399961,-!p3@SPI1!2.02!103.70!SPI1;;chr11:47400062..47400077,-!p2@SPI1!1.99!96.61!SPI1;;chr16:85932760..85932775,+!p1@IRF8!1.97!93.33!IRF8;;chr6:106534192..106534224,+!p1@PRDM1!1.95!237.43!PRDM1;;chr10:35484053..35484076,+!p1@CREM!1.92!195.95!CREM;;chr1:25256756..25256774,-!p1@RUNX3!1.90!144.37!RUNX3;;chr20:39317868..39317884,-!p1@MAFB!1.82!720.20!MAFB;;chr11:47400032..47400043,-!p5@SPI1!1.82!64.95!SPI1;;chr19:50432132..50432217,+!p2@ATF5!1.80!74.23!ATF5;;chr14:35872453..35872485,-!p2@NFKBIA!1.78!140.55!NFKBIA;;chr2:70142232..70142251,+!p1@MXD1!1.76!305.65!MXD1;;chr10:31288398..31288455,-!p2@ZNF438!1.76!64.95!ZNF438;;chr11:47399996..47400014,-!p4@SPI1!1.76!56.22!SPI1;;chr10:31288370..31288393,-!p3@ZNF438!1.75!54.85!ZNF438;;chr21:34398234..34398250,+!p1@OLIG2!1.72!51.58!OLIG2;;chr6:106534230..106534254,+!p2@PRDM1!1.66!108.34!PRDM1;;chr10:64018918..64018936,+!p2@ZNF365!1.66!44.21!ZNF365;;chr19:45971246..45971265,+!p1@FOSB!1.60!686.36!FOSB;;chr2:145277640..145277771,-!p1@ZEB2!1.55!438.29!ZEB2;;chr21:30671690..30671762,+!p2@BACH1!1.54!109.71!BACH1;;chr21:36260295..36260310,-!p3@RUNX1!1.54!53.76!RUNX1;;chr10:51572408..51572454,+!p3@NCOA4!1.53!183.12!NCOA4;;chr7:128577972..128578047,+!p1@IRF5!1.52!50.49!IRF5;;chr12:72056800..72056834,+!p1@THAP2!1.52!43.12!THAP2;;chr3:12330560..12330579,+!p1@PPARG!1.52!36.30!PPARG;;chr16:31885093..31885165,+!p1@ZNF267!1.50!442.11!ZNF267;;chr9:102584159..102584174,+!p2@NR4A3!1.49!52.67!NR4A3;;chr20:48599506..48599526,+!p1@SNAI1!1.48!180.12!SNAI1;;chr10:51572339..51572376,+!p4@NCOA4!1.48!63.86!NCOA4;;chr12:54778351..54778378,-!p6@ZNF385A!1.48!29.20!ZNF385A;;chr12:52445218..52445237,+!p1@NR4A1!1.47!345.23!NR4A1;;chr6:44233252..44233296,-!p1@NFKBIE!1.46!264.45!NFKBIE;;chr2:145275162..145275202,-!p2@ZEB2!1.46!159.65!ZEB2;;chr12:48298765..48298783,-!p2@VDR!1.46!57.58!VDR;;chr14:35873947..35873965,-!p1@NFKBIA!1.45!1656.54!NFKBIA;;chr13:41593425..41593480,-!p1@ELF1!1.44!161.29!ELF1;;chr2:68592394..68592405,+!p2@PLEK!1.44!26.74!PLEK;;chr1:212782094..212782109,+!p1@ATF3!1.43!676.53!ATF3;;chr2:157189180..157189290,-!p1@NR4A2!1.43!131.54!NR4A2;;chr6:144385698..144385742,-!p2@PLAGL1!1.41!30.02!PLAGL1;;chr11:47400045..47400060,-!p6@SPI1!1.41!24.56!SPI1;;chr20:48807351..48807384,+!p1@CEBPB!1.40!2328.71!CEBPB;;chr9:102584262..102584276,+!p1@NR4A3!1.40!52.67!NR4A3;;chr10:35484090..35484104,+!p6@CREM!1.40!24.29!CREM;;chr21:30671235..30671253,+!p1@BACH1!1.39!288.19!BACH1;;chr3:12329397..12329433,+!p2@PPARG!1.39!52.40!PPARG;;chr1:25256439..25256476,-!p3@RUNX3!1.38!23.20!RUNX3;;chr6:15246200..15246214,+!p2@JARID2!1.36!59.77!JARID2;;chr21:34442540..34442560,+!p2@OLIG1!1.36!21.83!OLIG1;;chrX:129244454..129244488,-!p1@ELF4!1.35!149.55!ELF4;;chr14:35872962..35873025,-!p3@NFKBIA!1.35!52.67!NFKBIA;;chr12:72056749..72056767,+!p6@THAP2!1.35!23.74!THAP2;;chr19:36391434..36391450,-!p1@NFKBID!1.34!40.66!NFKBID;;chr19:19496539..19496576,+!p8@GATAD2A!1.34!36.57!GATAD2A;;chrX:129244430..129244442,-!p5@ELF4!1.33!20.47!ELF4;;chr11:47399920..47399931,-!p7@SPI1!1.33!20.47!SPI1;;chr4:103422499..103422632,+!p1@NFKB1!1.32!401.17!NFKB1;;chr2:61108695..61108753,+!p1@REL!1.32!134.82!REL;;chr19:33793430..33793447,-!p1@CEBPA!1.32!82.69!CEBPA;;chr9:102584128..102584144,+!p3@NR4A3!1.32!37.39!NR4A3;;chr7:50344289..50344323,+!p1@IKZF1!1.30!18.83!IKZF1;;chr12:72056773..72056796,+!p3@THAP2!1.28!23.20!THAP2;;chr1:157108130..157108173,-!p1@ETV3!1.27!125.54!ETV3;;chr22:38597987..38598021,+!p2@MAFF!1.26!103.43!MAFF;;chr10:104154246..104154347,+!p3@NFKB2!1.26!103.43!NFKB2;;chr4:106068026..106068084,+!p1@TET2!1.25!149.55!TET2;;chr10:104155480..104155534,+!p2@NFKB2!1.25!107.80!NFKB2;;chr8:22550982..22550999,-!p1@EGR3!1.25!46.94!EGR3;;chr18:3449720..3449749,+!p2@TGIF1!1.25!35.48!TGIF1;;chr6:391743..391759,+!p1@IRF4!1.25!16.92!IRF4;;chr19:45251395..45251432,+!p8@BCL3!1.25!16.65!BCL3;;chr12:96588279..96588299,+!p4@ELK3!1.24!75.87!ELK3;;chr2:97202480..97202499,+!p1@ARID5A!1.23!157.74!ARID5A;;chr19:45252008..45252024,+!p2@BCL3!1.23!52.40!BCL3;;chr19:54041669..54041697,+!p2@ZNF331!1.23!15.83!ZNF331;;chr21:30672433..30672464,+!p6@BACH1!1.23!15.83!BACH1;;chr12:96588219..96588263,+!p2@ELK3!1.22!109.98!ELK3;;chr2:238600998..238601013,+!p5@LRRFIP1!1.22!15.56!LRRFIP1;;chrX:153305787..153305807,-!p3@MECP2!1.22!15.56!MECP2;;chr17:38497662..38497713,+!p4@RARA!1.21!17.74!RARA;;chr1:37940170..37940190,+!p1@ZC3H12A!1.20!178.48!ZC3H12A;;chr12:48298785..48298828,-!p1@VDR!1.20!78.32!VDR;;chr19:45250948..45250998,+!p3@BCL3!1.20!37.12!BCL3;;chr19:50432104..50432126,+!p6@ATF5!1.20!15.01!ATF5;;chr1:25291620..25291635,-!p4@RUNX3!1.20!14.74!RUNX3;;chr18:3449618..3449634,+!p13@TGIF1!1.19!18.01!TGIF1;;chr8:80679993..80680011,-!p1@HEY1!1.18!20.47!HEY1;;chr2:70314240..70314256,+!p4@PCBP1!1.17!28.66!PCBP1;;chr9:129567282..129567353,+!p1@ZBTB43!1.16!176.30!ZBTB43;;chr12:11802753..11802834,+!p2@ETV6!1.16!66.04!ETV6;;chr10:104155659..104155676,+!p4@NFKB2!1.16!16.92!NFKB2;;chr6:106535598..106535637,+!p7@PRDM1!1.15!13.10!PRDM1;;chr2:238600933..238600985,+!p3@LRRFIP1!1.14!68.50!LRRFIP1;;chr20:48807648..48807671,+!p9@CEBPB!1.14!18.56!CEBPB;;chr3:170075436..170075520,+!p1@SKIL!1.13!266.90!SKIL;;chr2:145277882..145277967,-!p3@ZEB2!1.13!21.83!ZEB2;;chr8:53373491..53373506,-!p4@ST18!1.13!12.55!ST18;;chr2:28615716..28615733,+!p1@FOSL2!1.12!568.46!FOSL2;;chr10:31288329..31288353,-!p7@ZNF438!1.12!12.28!ZNF438;;chr14:64971014..64971044,+!p4@ZBTB1!1.11!19.38!ZBTB1;;chr19:13213662..13213686,-!p1@LYL1!1.11!17.47!LYL1;;chr19:54058073..54058088,+!p1@ZNF331!1.11!12.01!ZNF331;;chr1:156470515..156470542,-!p2@MEF2D!1.10!60.31!MEF2D;;chr6:12012249..12012266,+!p5@HIVEP1!1.10!20.20!HIVEP1;;chr7:115670792..115670797,-!p2@TFEC!1.10!11.73!TFEC;;chr4:103423079..103423112,+!p4@NFKB1!1.10!11.46!NFKB1;;chr21:36421535..36421610,-!p2@RUNX1!1.09!40.66!RUNX1;;chr2:185463247..185463263,+!p1@ZNF804A!1.09!19.92!ZNF804A;;chr17:79881332..79881348,-!p3@MAFG!1.08!16.10!MAFG;;chr6:12012170..12012245,+!p1@HIVEP1!1.07!54.31!HIVEP1;;chr12:96588368..96588394,+!p3@ELK3!1.07!28.93!ELK3;;chr8:72756063..72756125,-!p1@MSC!1.07!22.11!MSC;;chr20:48807456..48807475,+!p3@CEBPB!1.07!20.74!CEBPB;;chr20:48807171..48807234,+!p4@CEBPB!1.06!23.20!CEBPB;;chr19:45254529..45254561,+!p10@BCL3!1.06!14.19!BCL3;;chr19:19496624..19496660,+!p3@GATAD2A!1.05!47.76!GATAD2A;;chr7:17338266..17338282,+!p1@AHR!1.04!109.44!AHR;;chr1:156470494..156470505,-!p3@MEF2D!1.04!14.46!MEF2D;;chr7:149470641..149470694,-!p1@ZNF467!1.03!44.48!ZNF467;;chr10:35484804..35484902,+!p2@CREM!1.03!38.21!CREM;;chr17:79885537..79885554,-!p2@MAFG!1.03!18.83!MAFG;;chr18:3449586..3449617,+!p8@TGIF1!1.03!15.56!TGIF1;;chr9:137217986..137218049,+!p3@RXRA!1.02!27.29!RXRA;;chr2:231280954..231280965,+!p2@SP100!1.02!17.47!SP100;;chr14:35872494..35872511,-!p5@NFKBIA!1.02!12.83!NFKBIA;;chr10:104155455..104155479,+!p1@NFKB2!1.01!138.64!NFKB2;;chr6:20403916..20403965,+!p3@E2F3!1.01!42.03!E2F3;;chr20:48809000..48809053,+!p12@CEBPB!1.00!12.01!CEBPB;;chr14:35872414..35872425,-!p7@NFKBIA!1.00!10.10!NFKBIA;;chr11:615942..615957,-!p1@IRF7!0.99!85.42!IRF7;;chr2:28618532..28618610,+!p4@FOSL2!0.99!15.28!FOSL2;;chr5:142782823..142782854,-!p3@NR3C1!0.99!12.83!NR3C1;;chr7:17338324..17338341,+!p3@AHR!0.98!29.47!AHR;;chr18:3448455..3448480,+!p5@TGIF1!0.98!16.10!TGIF1;;chr18:3449695..3449712,+!p9@TGIF1!0.98!13.37!TGIF1;;chr2:70167296..70167306,+!p3@MXD1!0.98!13.37!MXD1;;chr2:113999360..113999386,-!p4@PAX8!0.98!8.46!PAX8;;chr17:38474489..38474548,+!p1@RARA!0.97!272.36!RARA;;chr20:48807615..48807644,+!p6@CEBPB!0.97!14.19!CEBPB;;chr9:117150254..117150271,-!p1@AKNA!0.96!22.65!AKNA;;chr2:61108771..61108789,+!p4@REL!0.96!12.55!REL;;chr3:101546827..101546847,+!p2@NFKBIZ!0.96!11.46!NFKBIZ;;chr19:12902289..12902307,+!p1@JUNB!0.95!1887.69!JUNB;;chr19:45251943..45252006,+!p1@BCL3!0.95!214.50!BCL3;;chr6:15246261..15246312,+!p1@JARID2!0.95!197.58!JARID2;;chr12:124873852..124873881,-!p3@NCOR2!0.95!49.12!NCOR2;;chr6:12011943..12012015,+!p2@HIVEP1!0.95!25.93!HIVEP1;;chr20:48807143..48807165,+!p11@CEBPB!0.95!12.01!CEBPB;;chr13:41593392..41593403,-!p7@ELF1!0.95!7.91!ELF1;;chr18:3449527..3449582,+!p6@TGIF1!0.94!15.01!TGIF1;;chr21:36260343..36260402,-!p6@RUNX1!0.94!12.55!RUNX1;;chr5:71803177..71803255,-!p1@ZNF366!0.94!7.64!ZNF366;;chr2:74730430..74730451,-!p1@LBX2!0.93!12.55!LBX2;;chr2:192015701..192015743,-!p1@STAT4!0.93!10.37!STAT4;;chr1:38325227..38325246,-!p2@MTF1!0.93!10.37!MTF1;;chr21:36260980..36261011,-!p1@RUNX1!0.92!218.60!RUNX1;;chr11:65430554..65430579,-!p3@RELA!0.92!19.10!RELA;;chr2:61108808..61108821,+!p3@REL!0.92!9.28!REL;;chr2:231090471..231090504,+!p2@SP140!0.92!7.37!SP140;;chr3:126191157..126191171,-!p4@ZXDC!0.92!7.37!ZXDC;;chr1:25291648..25291665,-!p7@RUNX3!0.92!7.37!RUNX3;;chr5:88178983..88179012,-!p1@MEF2C!0.91!57.04!MEF2C;;chr4:81104895..81104920,+!p2@PRDM8!0.91!10.92!PRDM8;;chr3:18466660..18466676,-!p5@SATB1!0.91!8.46!SATB1;;chr3:12329464..12329472,+!p6@PPARG!0.91!7.10!PPARG;;chr9:88969303..88969335,-!p1@ZCCHC6!0.90!67.95!ZCCHC6;;chr10:35416142..35416169,+!p3@CREM!0.90!19.10!CREM;;chr1:221052776..221052799,+!p1@HLX!0.90!12.83!HLX;;chr2:70142189..70142223,+!p2@MXD1!0.89!50.21!MXD1;;chr3:39195037..39195069,-!p2@CSRNP1!0.89!43.94!CSRNP1;;chr13:41635029..41635044,-!p4@ELF1!0.89!14.74!ELF1;;chr19:45254508..45254528,+!p12@BCL3!0.89!7.37!BCL3;;chr7:137620684..137620711,-!p4@CREB3L2!0.89!6.82!CREB3L2;;chr17:38498402..38498445,+!p3@RARA!0.88!24.83!RARA;;chr14:35872926..35872951,-!p4@NFKBIA!0.88!9.55!NFKBIA;;chr2:145275228..145275241,-!p11@ZEB2!0.88!8.19!ZEB2;;chr3:101568349..101568365,+!p1@NFKBIZ!0.87!353.14!NFKBIZ;;chr9:88969339..88969422,-!p2@ZCCHC6!0.87!53.22!ZCCHC6;;chr2:208394817..208394834,+!p3@CREB1!0.87!27.29!CREB1;;chr6:15246217..1524622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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000634,FF:0011105,FF:11877-125C5 | |fonse_treatment=FF:0000625,FF:0000634,FF:0011105,FF:11877-125C5 | ||
|fonse_treatment_closure=FF:0000625,FF:0000634,FF:0011105,FF:11877-125C5 | |fonse_treatment_closure=FF:0000625,FF:0000634,FF:0011105,FF:11877-125C5 | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor2.CNhs13487.11877-125C5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor2.CNhs13487.11877-125C5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor2.CNhs13487.11877-125C5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor2.CNhs13487.11877-125C5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor2.CNhs13487.11877-125C5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11877-125C5 | |||
|is_a=EFO:0002091;;FF:0011105 | |||
|is_obsolete= | |||
|library_id=CNhs13487 | |||
|library_id_phase_based=2:CNhs13487 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11877 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11877 | |||
|name=CD14+ monocytes - treated with Cryptococcus, donor2 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13487,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.77631 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-8 | |||
|rna_od260/230=1.78 | |||
|rna_od260/280=2.02 | |||
|rna_position=C5 | |||
|rna_rin=9.2 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125C5 | |||
|rna_weight_ug=3.493395 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.99790677707004e-256!GO:0005737;cytoplasm;6.73894085484972e-128!GO:0043227;membrane-bound organelle;8.18830482310532e-128!GO:0043231;intracellular membrane-bound organelle;1.83088621008547e-127!GO:0043226;organelle;7.94168323143812e-120!GO:0043229;intracellular organelle;5.59462615678423e-119!GO:0044444;cytoplasmic part;3.8840360260192e-85!GO:0044422;organelle part;2.95080239942288e-73!GO:0044446;intracellular organelle part;1.17633103686665e-71!GO:0044237;cellular metabolic process;1.21857963270879e-71!GO:0044238;primary metabolic process;1.39903823219884e-70!GO:0043170;macromolecule metabolic process;3.05709200419695e-69!GO:0005515;protein binding;3.6545367807811e-69!GO:0032991;macromolecular complex;3.34590157066877e-63!GO:0003723;RNA binding;2.13168814408364e-55!GO:0005634;nucleus;2.87607784582382e-54!GO:0030529;ribonucleoprotein complex;1.39962385831401e-53!GO:0044428;nuclear part;9.14228125487721e-50!GO:0019538;protein metabolic process;4.2963521372669e-48!GO:0044267;cellular protein metabolic process;9.49988406314372e-45!GO:0044260;cellular macromolecule metabolic process;2.87804680745008e-44!GO:0033036;macromolecule localization;4.9413478547801e-44!GO:0045184;establishment of protein localization;3.77662372248425e-43!GO:0015031;protein transport;3.77662372248425e-43!GO:0006412;translation;5.17739206543784e-41!GO:0043233;organelle lumen;9.04282817048617e-41!GO:0031974;membrane-enclosed lumen;9.04282817048617e-41!GO:0008104;protein localization;9.04282817048617e-41!GO:0043283;biopolymer metabolic process;2.35217148475216e-39!GO:0010467;gene expression;2.99670393829288e-38!GO:0005829;cytosol;8.59259712618649e-36!GO:0031090;organelle membrane;2.26701173744292e-34!GO:0016071;mRNA metabolic process;8.37155132206541e-33!GO:0006396;RNA processing;9.45698894150492e-33!GO:0043234;protein complex;3.44431820833827e-32!GO:0031981;nuclear lumen;1.00820844724455e-31!GO:0016043;cellular component organization and biogenesis;2.94412361416736e-30!GO:0009059;macromolecule biosynthetic process;3.23722377439849e-30!GO:0046907;intracellular transport;3.32058837146748e-30!GO:0008380;RNA splicing;9.0641825029119e-30!GO:0006915;apoptosis;1.09203991725783e-29!GO:0012501;programmed cell death;1.11469243657855e-29!GO:0044249;cellular biosynthetic process;2.19358175451335e-29!GO:0009058;biosynthetic process;2.42916361521171e-29!GO:0006886;intracellular protein transport;8.65481231769429e-29!GO:0005840;ribosome;1.34692454102275e-28!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.58750009147952e-28!GO:0006397;mRNA processing;3.18124810450736e-28!GO:0008219;cell death;5.19983617513374e-28!GO:0016265;death;5.19983617513374e-28!GO:0005739;mitochondrion;8.63729297945667e-27!GO:0003735;structural constituent of ribosome;2.85139765935666e-26!GO:0031967;organelle envelope;1.73706942790876e-25!GO:0031975;envelope;3.2797527585198e-25!GO:0033279;ribosomal subunit;3.33066829958418e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.49112040961315e-24!GO:0051649;establishment of cellular localization;8.76448821383541e-24!GO:0051641;cellular localization;5.80460873221286e-23!GO:0065003;macromolecular complex assembly;2.43484044045011e-22!GO:0044445;cytosolic part;5.91264517508335e-22!GO:0005654;nucleoplasm;8.0805774229676e-22!GO:0005681;spliceosome;1.28470159245498e-21!GO:0008134;transcription factor binding;5.4777349129898e-21!GO:0044429;mitochondrial part;2.20122560258823e-20!GO:0042981;regulation of apoptosis;6.61294675608591e-20!GO:0000166;nucleotide binding;8.61223821520136e-20!GO:0043067;regulation of programmed cell death;1.62601602105673e-19!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.42734442759399e-18!GO:0022607;cellular component assembly;1.68120840946173e-18!GO:0044451;nucleoplasm part;2.15751059772017e-18!GO:0016192;vesicle-mediated transport;3.12963144024059e-18!GO:0016070;RNA metabolic process;3.98664623505974e-18!GO:0048770;pigment granule;6.19933136923e-18!GO:0042470;melanosome;6.19933136923e-18!GO:0006119;oxidative phosphorylation;2.15006354288325e-17!GO:0044265;cellular macromolecule catabolic process;3.32178474623462e-17!GO:0043412;biopolymer modification;5.5121807922261e-17!GO:0003676;nucleic acid binding;6.23091296729591e-17!GO:0007243;protein kinase cascade;1.0585991728053e-16!GO:0006512;ubiquitin cycle;1.57269937699927e-16!GO:0048523;negative regulation of cellular process;3.00463330270425e-16!GO:0005740;mitochondrial envelope;3.82496677754584e-16!GO:0022618;protein-RNA complex assembly;4.26096130920876e-16!GO:0006464;protein modification process;7.26325440684405e-16!GO:0050794;regulation of cellular process;7.29623794351057e-16!GO:0031966;mitochondrial membrane;1.2742654764682e-15!GO:0043687;post-translational protein modification;1.88845451311802e-15!GO:0005773;vacuole;2.20112371506176e-15!GO:0043285;biopolymer catabolic process;2.3591171520038e-15!GO:0007242;intracellular signaling cascade;3.24989057503308e-15!GO:0017111;nucleoside-triphosphatase activity;3.54349102043815e-15!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.95264764951899e-15!GO:0016462;pyrophosphatase activity;4.01236034283095e-15!GO:0016817;hydrolase activity, acting on acid anhydrides;4.84075637745418e-15!GO:0006996;organelle organization and biogenesis;5.26233451375749e-15!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.68016599490573e-15!GO:0019866;organelle inner membrane;7.71469689603077e-15!GO:0006605;protein targeting;8.73023578238956e-15!GO:0048519;negative regulation of biological process;1.10302258051277e-14!GO:0019941;modification-dependent protein catabolic process;1.48279551202527e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.48279551202527e-14!GO:0016604;nuclear body;1.66374534639388e-14!GO:0032553;ribonucleotide binding;1.87837074602409e-14!GO:0032555;purine ribonucleotide binding;1.87837074602409e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.87837074602409e-14!GO:0044257;cellular protein catabolic process;1.90398718930916e-14!GO:0006511;ubiquitin-dependent protein catabolic process;2.04682729815801e-14!GO:0009057;macromolecule catabolic process;3.1229520186161e-14!GO:0016874;ligase activity;5.61390779962577e-14!GO:0017076;purine nucleotide binding;6.69496420019408e-14!GO:0006913;nucleocytoplasmic transport;8.13103838340125e-14!GO:0000323;lytic vacuole;1.0482076167534e-13!GO:0005764;lysosome;1.0482076167534e-13!GO:0051169;nuclear transport;1.65087861436062e-13!GO:0043069;negative regulation of programmed cell death;1.97824996637836e-13!GO:0043066;negative regulation of apoptosis;2.02709785449458e-13!GO:0003712;transcription cofactor activity;3.07115216079633e-13!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;5.24447054962661e-13!GO:0050789;regulation of biological process;5.70346928086508e-13!GO:0015934;large ribosomal subunit;5.7682716142347e-13!GO:0016607;nuclear speck;6.93189869114937e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);8.974287335331e-13!GO:0008135;translation factor activity, nucleic acid binding;8.99767435019767e-13!GO:0000502;proteasome complex (sensu Eukaryota);1.0076742907186e-12!GO:0044248;cellular catabolic process;1.13319171910873e-12!GO:0030163;protein catabolic process;1.26007340536654e-12!GO:0012505;endomembrane system;1.27141407396714e-12!GO:0005794;Golgi apparatus;2.47628495284416e-12!GO:0006793;phosphorus metabolic process;2.5468318865918e-12!GO:0006796;phosphate metabolic process;2.5468318865918e-12!GO:0065009;regulation of a molecular function;2.86835911893189e-12!GO:0005768;endosome;3.12916071798658e-12!GO:0005743;mitochondrial inner membrane;3.3695471973509e-12!GO:0015935;small ribosomal subunit;3.78046845242486e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.02297402774725e-12!GO:0051246;regulation of protein metabolic process;5.3983094230831e-12!GO:0006366;transcription from RNA polymerase II promoter;7.37991933817642e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;8.78886499542023e-12!GO:0065007;biological regulation;1.0012073690687e-11!GO:0003743;translation initiation factor activity;1.11295394353632e-11!GO:0006457;protein folding;1.36675036711341e-11!GO:0006413;translational initiation;2.02502107126763e-11!GO:0044455;mitochondrial membrane part;2.21100756146904e-11!GO:0002376;immune system process;5.14560717462148e-11!GO:0006916;anti-apoptosis;6.57707575070663e-11!GO:0006446;regulation of translational initiation;8.48349953914639e-11!GO:0016310;phosphorylation;8.71778152101312e-11!GO:0006259;DNA metabolic process;8.72599778823609e-11!GO:0051186;cofactor metabolic process;1.32269372533193e-10!GO:0006950;response to stress;1.96221468273449e-10!GO:0051082;unfolded protein binding;3.63846042730784e-10!GO:0005730;nucleolus;4.55586885319821e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.23220720969628e-10!GO:0006732;coenzyme metabolic process;6.61058564860753e-10!GO:0005524;ATP binding;7.06538270172244e-10!GO:0048193;Golgi vesicle transport;7.29328344981691e-10!GO:0032559;adenyl ribonucleotide binding;8.19549875958928e-10!GO:0005635;nuclear envelope;1.48411562451394e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;1.48411562451394e-09!GO:0000375;RNA splicing, via transesterification reactions;1.48411562451394e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.48411562451394e-09!GO:0031324;negative regulation of cellular metabolic process;1.72883903457052e-09!GO:0048522;positive regulation of cellular process;1.76147077301264e-09!GO:0019222;regulation of metabolic process;1.92179783957084e-09!GO:0005770;late endosome;2.06225520973229e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.25602777342302e-09!GO:0005746;mitochondrial respiratory chain;2.41184662835576e-09!GO:0019829;cation-transporting ATPase activity;2.67655150236895e-09!GO:0008639;small protein conjugating enzyme activity;2.71322734921049e-09!GO:0030554;adenyl nucleotide binding;2.72187121338181e-09!GO:0005783;endoplasmic reticulum;3.30535986996905e-09!GO:0015986;ATP synthesis coupled proton transport;3.31163921210515e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.31163921210515e-09!GO:0016787;hydrolase activity;3.31163921210515e-09!GO:0019787;small conjugating protein ligase activity;3.94649390804597e-09!GO:0017038;protein import;4.66581766706604e-09!GO:0004842;ubiquitin-protein ligase activity;5.76256293386926e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.1310535563693e-09!GO:0009967;positive regulation of signal transduction;6.39571357785221e-09!GO:0048518;positive regulation of biological process;6.64370152832318e-09!GO:0050790;regulation of catalytic activity;9.69363585886463e-09!GO:0050136;NADH dehydrogenase (quinone) activity;1.27963592497504e-08!GO:0003954;NADH dehydrogenase activity;1.27963592497504e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.27963592497504e-08!GO:0009056;catabolic process;1.35229421176759e-08!GO:0016564;transcription repressor activity;1.3825558037466e-08!GO:0051170;nuclear import;1.62293702781174e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.84730545935618e-08!GO:0006955;immune response;2.05653687435065e-08!GO:0006164;purine nucleotide biosynthetic process;2.18684452313007e-08!GO:0007049;cell cycle;2.29750024145763e-08!GO:0016881;acid-amino acid ligase activity;2.49858000006386e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.57083442162744e-08!GO:0009150;purine ribonucleotide metabolic process;2.57083442162744e-08!GO:0006163;purine nucleotide metabolic process;2.70193134694273e-08!GO:0005774;vacuolar membrane;2.75776236484805e-08!GO:0031965;nuclear membrane;3.17458961179688e-08!GO:0006417;regulation of translation;3.17458961179688e-08!GO:0003713;transcription coactivator activity;3.22881477334347e-08!GO:0043228;non-membrane-bound organelle;3.73148842774269e-08!GO:0043232;intracellular non-membrane-bound organelle;3.73148842774269e-08!GO:0006606;protein import into nucleus;4.00363184379698e-08!GO:0009892;negative regulation of metabolic process;4.17706059137555e-08!GO:0006754;ATP biosynthetic process;4.3029630250958e-08!GO:0006753;nucleoside phosphate metabolic process;4.3029630250958e-08!GO:0044453;nuclear membrane part;5.28288036250008e-08!GO:0043065;positive regulation of apoptosis;5.4696277962985e-08!GO:0008565;protein transporter activity;5.50350139972446e-08!GO:0008047;enzyme activator activity;5.66402725952229e-08!GO:0016887;ATPase activity;6.74001022078468e-08!GO:0019899;enzyme binding;7.77062682843786e-08!GO:0016469;proton-transporting two-sector ATPase complex;8.00171224486607e-08!GO:0043068;positive regulation of programmed cell death;8.00171224486607e-08!GO:0042775;organelle ATP synthesis coupled electron transport;8.20846231657273e-08!GO:0042773;ATP synthesis coupled electron transport;8.20846231657273e-08!GO:0044440;endosomal part;8.28012425612029e-08!GO:0010008;endosome membrane;8.28012425612029e-08!GO:0016481;negative regulation of transcription;1.0239742895291e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.09911633585601e-07!GO:0006461;protein complex assembly;1.09911633585601e-07!GO:0009259;ribonucleotide metabolic process;1.1196622732197e-07!GO:0042623;ATPase activity, coupled;1.138626451197e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.17620003592797e-07!GO:0009615;response to virus;1.20439568227984e-07!GO:0007264;small GTPase mediated signal transduction;1.24634360001155e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.40508516283079e-07!GO:0009055;electron carrier activity;1.44342296315771e-07!GO:0044437;vacuolar part;1.48639601420873e-07!GO:0005525;GTP binding;1.55944058350662e-07!GO:0009108;coenzyme biosynthetic process;1.55944058350662e-07!GO:0009260;ribonucleotide biosynthetic process;1.70720539048785e-07!GO:0051726;regulation of cell cycle;1.87354885324261e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.89892980578468e-07!GO:0045271;respiratory chain complex I;1.89892980578468e-07!GO:0005747;mitochondrial respiratory chain complex I;1.89892980578468e-07!GO:0003924;GTPase activity;1.90343692902099e-07!GO:0005765;lysosomal membrane;1.91099011621119e-07!GO:0051188;cofactor biosynthetic process;1.92690912579358e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.13754439339723e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.13754439339723e-07!GO:0005793;ER-Golgi intermediate compartment;2.3354583283306e-07!GO:0000074;regulation of progression through cell cycle;2.74717225393611e-07!GO:0031982;vesicle;2.81976257351888e-07!GO:0031323;regulation of cellular metabolic process;3.30515606023954e-07!GO:0046034;ATP metabolic process;3.37837757874895e-07!GO:0009142;nucleoside triphosphate biosynthetic process;3.48628161445855e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.48628161445855e-07!GO:0009889;regulation of biosynthetic process;3.67746223218085e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.77873066404039e-07!GO:0045786;negative regulation of progression through cell cycle;4.37785874374395e-07!GO:0044432;endoplasmic reticulum part;4.42833692595891e-07!GO:0050657;nucleic acid transport;4.45010777071156e-07!GO:0051236;establishment of RNA localization;4.45010777071156e-07!GO:0050658;RNA transport;4.45010777071156e-07!GO:0031326;regulation of cellular biosynthetic process;5.24007766790232e-07!GO:0048468;cell development;5.84704601078257e-07!GO:0006403;RNA localization;6.12692770368598e-07!GO:0009966;regulation of signal transduction;7.01071732737493e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;7.67287732499932e-07!GO:0009144;purine nucleoside triphosphate metabolic process;7.67287732499932e-07!GO:0032446;protein modification by small protein conjugation;8.10431996693296e-07!GO:0016568;chromatin modification;8.71245616245445e-07!GO:0006917;induction of apoptosis;9.11219838615852e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.14296800793265e-06!GO:0006752;group transfer coenzyme metabolic process;1.4110150501675e-06!GO:0012502;induction of programmed cell death;1.48390949951303e-06!GO:0016563;transcription activator activity;1.67212048816345e-06!GO:0016567;protein ubiquitination;1.87983905162633e-06!GO:0031980;mitochondrial lumen;2.06228122003138e-06!GO:0005759;mitochondrial matrix;2.06228122003138e-06!GO:0031410;cytoplasmic vesicle;2.20667715074351e-06!GO:0005643;nuclear pore;2.25684556902522e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;2.29179093174842e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.49335770061408e-06!GO:0009141;nucleoside triphosphate metabolic process;2.72926364283094e-06!GO:0016044;membrane organization and biogenesis;2.99184091923485e-06!GO:0032561;guanyl ribonucleotide binding;3.36644168622063e-06!GO:0019001;guanyl nucleotide binding;3.36644168622063e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.7826517072495e-06!GO:0016197;endosome transport;4.32509077788034e-06!GO:0009607;response to biotic stimulus;4.34986483370277e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.70105421016299e-06!GO:0008026;ATP-dependent helicase activity;4.82440279675665e-06!GO:0003714;transcription corepressor activity;4.87280948493289e-06!GO:0031988;membrane-bound vesicle;4.87616204419499e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.98312171379634e-06!GO:0006323;DNA packaging;6.39734198910603e-06!GO:0051028;mRNA transport;7.0718452388611e-06!GO:0004386;helicase activity;7.08350944938383e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;7.83212434973337e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;7.97496556434839e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;8.42326509607467e-06!GO:0010468;regulation of gene expression;8.82434254858933e-06!GO:0005839;proteasome core complex (sensu Eukaryota);9.03592898456178e-06!GO:0005789;endoplasmic reticulum membrane;9.20055792075767e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.20095199927967e-05!GO:0015399;primary active transmembrane transporter activity;1.20095199927967e-05!GO:0030695;GTPase regulator activity;1.27765480363268e-05!GO:0031252;leading edge;1.34447601571392e-05!GO:0005096;GTPase activator activity;1.35920126679157e-05!GO:0048475;coated membrane;1.40546691588426e-05!GO:0030117;membrane coat;1.40546691588426e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.40560298838957e-05!GO:0016023;cytoplasmic membrane-bound vesicle;1.92522914013253e-05!GO:0031902;late endosome membrane;1.92765001090305e-05!GO:0003724;RNA helicase activity;1.97122769785045e-05!GO:0046930;pore complex;2.28334955921645e-05!GO:0051168;nuclear export;2.52903205157525e-05!GO:0006974;response to DNA damage stimulus;3.12284515224661e-05!GO:0022402;cell cycle process;3.1269985227824e-05!GO:0005769;early endosome;3.43994161727894e-05!GO:0030120;vesicle coat;3.8092085866176e-05!GO:0030662;coated vesicle membrane;3.8092085866176e-05!GO:0006350;transcription;4.705559570335e-05!GO:0045259;proton-transporting ATP synthase complex;5.02823990657223e-05!GO:0004298;threonine endopeptidase activity;5.0302547520795e-05!GO:0065002;intracellular protein transport across a membrane;5.76973452012932e-05!GO:0006613;cotranslational protein targeting to membrane;6.04024047319697e-05!GO:0006401;RNA catabolic process;6.36843284090925e-05!GO:0051336;regulation of hydrolase activity;6.5334522847941e-05!GO:0051427;hormone receptor binding;7.4582856148599e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.4582856148599e-05!GO:0045892;negative regulation of transcription, DNA-dependent;7.64009053509668e-05!GO:0008632;apoptotic program;7.85806383502138e-05!GO:0043566;structure-specific DNA binding;8.00812968893186e-05!GO:0032940;secretion by cell;8.89005519847791e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.20129387760822e-05!GO:0006897;endocytosis;9.71758921437569e-05!GO:0010324;membrane invagination;9.71758921437569e-05!GO:0042254;ribosome biogenesis and assembly;0.000101463103187566!GO:0030532;small nuclear ribonucleoprotein complex;0.00010545383246485!GO:0003697;single-stranded DNA binding;0.000117284094384543!GO:0051276;chromosome organization and biogenesis;0.000118698584883043!GO:0051789;response to protein stimulus;0.000130686106087084!GO:0006986;response to unfolded protein;0.000130686106087084!GO:0035257;nuclear hormone receptor binding;0.000130706127647935!GO:0046519;sphingoid metabolic process;0.00013537279530265!GO:0004674;protein serine/threonine kinase activity;0.000141904806598995!GO:0006818;hydrogen transport;0.000141959724334133!GO:0009060;aerobic respiration;0.00014842629072516!GO:0046822;regulation of nucleocytoplasmic transport;0.000152913735746645!GO:0044431;Golgi apparatus part;0.000161158351795813!GO:0005057;receptor signaling protein activity;0.000162294053989864!GO:0001816;cytokine production;0.000168153838900702!GO:0006281;DNA repair;0.000169519757557232!GO:0000245;spliceosome assembly;0.000172562514248206!GO:0043492;ATPase activity, coupled to movement of substances;0.000172562514248206!GO:0009893;positive regulation of metabolic process;0.000173668663668515!GO:0007033;vacuole organization and biogenesis;0.000180137235580228!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000183091292241061!GO:0007040;lysosome organization and biogenesis;0.000191793743902926!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000194779631566518!GO:0007265;Ras protein signal transduction;0.000200342158451262!GO:0005083;small GTPase regulator activity;0.00020293863385161!GO:0005885;Arp2/3 protein complex;0.000236260118133299!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000237763853803382!GO:0015992;proton transport;0.000239785540616259!GO:0007034;vacuolar transport;0.000258732963020438!GO:0006672;ceramide metabolic process;0.000259991613673106!GO:0051338;regulation of transferase activity;0.000260645644604806!GO:0030036;actin cytoskeleton organization and biogenesis;0.000261299248276736!GO:0008234;cysteine-type peptidase activity;0.000278216620733936!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000285251228746693!GO:0007050;cell cycle arrest;0.000303363243628792!GO:0008186;RNA-dependent ATPase activity;0.000303363243628792!GO:0016740;transferase activity;0.000325997974211931!GO:0002757;immune response-activating signal transduction;0.00032908929527585!GO:0030099;myeloid cell differentiation;0.000344772962123343!GO:0045333;cellular respiration;0.000348981741336359!GO:0005761;mitochondrial ribosome;0.000374109336943516!GO:0000313;organellar ribosome;0.000374109336943516!GO:0000151;ubiquitin ligase complex;0.000378644598167884!GO:0006402;mRNA catabolic process;0.000407163646879765!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000435747585753242!GO:0022890;inorganic cation transmembrane transporter activity;0.000445715632201283!GO:0051223;regulation of protein transport;0.000469488583026918!GO:0005798;Golgi-associated vesicle;0.000517509641703651!GO:0045321;leukocyte activation;0.000518312800440243!GO:0043085;positive regulation of catalytic activity;0.000577154035276749!GO:0007041;lysosomal transport;0.000591287155276096!GO:0001726;ruffle;0.000599046751940422!GO:0009117;nucleotide metabolic process;0.000643869264188868!GO:0043549;regulation of kinase activity;0.000667952067336568!GO:0007005;mitochondrion organization and biogenesis;0.000718418125414694!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000728579598436134!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000766637748623353!GO:0004812;aminoacyl-tRNA ligase activity;0.000766637748623353!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000766637748623353!GO:0006399;tRNA metabolic process;0.000798345910866949!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000801154107980648!GO:0003729;mRNA binding;0.000822185874211053!GO:0002764;immune response-regulating signal transduction;0.000822185874211053!GO:0004004;ATP-dependent RNA helicase activity;0.000909690876853855!GO:0006612;protein targeting to membrane;0.000918548549482452!GO:0060090;molecular adaptor activity;0.000924683487412866!GO:0005637;nuclear inner membrane;0.000939379990760525!GO:0045859;regulation of protein kinase activity;0.000958378824717158!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000962424303066713!GO:0033157;regulation of intracellular protein transport;0.000977209302442821!GO:0042306;regulation of protein import into nucleus;0.000977209302442821!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000985173070988064!GO:0031072;heat shock protein binding;0.000994641596977708!GO:0033116;ER-Golgi intermediate compartment membrane;0.00100679214405756!GO:0051090;regulation of transcription factor activity;0.00101476434434801!GO:0045941;positive regulation of transcription;0.00103357398184309!GO:0030149;sphingolipid catabolic process;0.00115962554849526!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00117312953996731!GO:0008654;phospholipid biosynthetic process;0.00117396664239132!GO:0005741;mitochondrial outer membrane;0.00119107934624041!GO:0005667;transcription factor complex;0.00126158882622798!GO:0043038;amino acid activation;0.0012661904385682!GO:0006418;tRNA aminoacylation for protein translation;0.0012661904385682!GO:0043039;tRNA aminoacylation;0.0012661904385682!GO:0006643;membrane lipid metabolic process;0.00135664082093778!GO:0043623;cellular protein complex assembly;0.00141140966294688!GO:0005099;Ras GTPase activator activity;0.00162328699809409!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00166584083609614!GO:0006954;inflammatory response;0.00171183794683325!GO:0046983;protein dimerization activity;0.00171397858442488!GO:0045449;regulation of transcription;0.00177115346918466!GO:0022415;viral reproductive process;0.00177272707211743!GO:0018193;peptidyl-amino acid modification;0.00181609895030871!GO:0009719;response to endogenous stimulus;0.00181912926151664!GO:0006919;caspase activation;0.00187963705760965!GO:0031325;positive regulation of cellular metabolic process;0.00189170992559462!GO:0016251;general RNA polymerase II transcription factor activity;0.00189170992559462!GO:0043087;regulation of GTPase activity;0.00190972505961663!GO:0045893;positive regulation of transcription, DNA-dependent;0.00191459664927761!GO:0030097;hemopoiesis;0.00199256818252047!GO:0002274;myeloid leukocyte activation;0.00205973455004765!GO:0006351;transcription, DNA-dependent;0.00210442810186025!GO:0045454;cell redox homeostasis;0.0021564046557244!GO:0032774;RNA biosynthetic process;0.00228411922103941!GO:0044262;cellular carbohydrate metabolic process;0.00228516794407269!GO:0016363;nuclear matrix;0.00240537074274342!GO:0016301;kinase activity;0.00261016505821155!GO:0065004;protein-DNA complex assembly;0.00265267961797905!GO:0043281;regulation of caspase activity;0.00267645603028018!GO:0042990;regulation of transcription factor import into nucleus;0.00276691895027!GO:0042991;transcription factor import into nucleus;0.00276691895027!GO:0031901;early endosome membrane;0.00276691895027!GO:0048487;beta-tubulin binding;0.00276691895027!GO:0019867;outer membrane;0.00276951992667598!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.0027746314983231!GO:0030029;actin filament-based process;0.00283278697471068!GO:0045045;secretory pathway;0.00286948163174486!GO:0006091;generation of precursor metabolites and energy;0.00338042891266901!GO:0019904;protein domain specific binding;0.00341343499373903!GO:0001817;regulation of cytokine production;0.00355771096228206!GO:0045637;regulation of myeloid cell differentiation;0.0036079855907053!GO:0043280;positive regulation of caspase activity;0.00361540329310659!GO:0009165;nucleotide biosynthetic process;0.0036285904035593!GO:0031968;organelle outer membrane;0.00365604875593648!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0037605453523716!GO:0016072;rRNA metabolic process;0.00380089612457736!GO:0006099;tricarboxylic acid cycle;0.00419936590357705!GO:0046356;acetyl-CoA catabolic process;0.00419936590357705!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00435063468891284!GO:0043021;ribonucleoprotein binding;0.00437555148667286!GO:0000139;Golgi membrane;0.00438835891399894!GO:0046966;thyroid hormone receptor binding;0.00443570173682!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00450761729484126!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00450761729484126!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00450761729484126!GO:0006665;sphingolipid metabolic process;0.00463174452106736!GO:0006468;protein amino acid phosphorylation;0.00471815905103384!GO:0051187;cofactor catabolic process;0.00477759863476598!GO:0016779;nucleotidyltransferase activity;0.00477759863476598!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00478964804924112!GO:0006891;intra-Golgi vesicle-mediated transport;0.00478964804924112!GO:0006364;rRNA processing;0.00499720961072242!GO:0006607;NLS-bearing substrate import into nucleus;0.00527421881943421!GO:0019377;glycolipid catabolic process;0.00540001651607097!GO:0051707;response to other organism;0.00563652502748139!GO:0005484;SNAP receptor activity;0.00570887835343499!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00627804707690533!GO:0030521;androgen receptor signaling pathway;0.00631124427135628!GO:0050851;antigen receptor-mediated signaling pathway;0.00631124427135628!GO:0006352;transcription initiation;0.00635319674602911!GO:0003702;RNA polymerase II transcription factor activity;0.00652607045548466!GO:0001775;cell activation;0.00652739108375239!GO:0046649;lymphocyte activation;0.00677269502514422!GO:0004197;cysteine-type endopeptidase activity;0.00703400941393144!GO:0046479;glycosphingolipid catabolic process;0.00740300733712513!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00751908567600585!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00757134292925168!GO:0042802;identical protein binding;0.00798733182638753!GO:0004185;serine carboxypeptidase activity;0.00798971967916858!GO:0045920;negative regulation of exocytosis;0.0081013338931891!GO:0043301;negative regulation of leukocyte degranulation;0.0081013338931891!GO:0043305;negative regulation of mast cell degranulation;0.0081013338931891!GO:0005070;SH3/SH2 adaptor activity;0.00821545752971843!GO:0006611;protein export from nucleus;0.00830565130365331!GO:0001819;positive regulation of cytokine production;0.00838212503576403!GO:0006333;chromatin assembly or disassembly;0.00839127017660369!GO:0008270;zinc ion binding;0.00851756798111455!GO:0030134;ER to Golgi transport vesicle;0.00865143787941435!GO:0005813;centrosome;0.00894399751550441!GO:0032386;regulation of intracellular transport;0.00906125042450006!GO:0006084;acetyl-CoA metabolic process;0.00918307733658949!GO:0006749;glutathione metabolic process;0.00954851621828245!GO:0016791;phosphoric monoester hydrolase activity;0.00963696523796168!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.00991677221633689!GO:0002819;regulation of adaptive immune response;0.00991677221633689!GO:0048500;signal recognition particle;0.01004730771458!GO:0042110;T cell activation;0.01004730771458!GO:0030518;steroid hormone receptor signaling pathway;0.01004730771458!GO:0043433;negative regulation of transcription factor activity;0.0102625269439033!GO:0002252;immune effector process;0.0103691030310298!GO:0031625;ubiquitin protein ligase binding;0.0104282435264732!GO:0002444;myeloid leukocyte mediated immunity;0.0108484801083052!GO:0008383;manganese superoxide dismutase activity;0.0108951102827844!GO:0001315;age-dependent response to reactive oxygen species;0.0108951102827844!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0116605681035191!GO:0030127;COPII vesicle coat;0.0117672990184804!GO:0012507;ER to Golgi transport vesicle membrane;0.0117672990184804!GO:0051092;activation of NF-kappaB transcription factor;0.011894217188729!GO:0000082;G1/S transition of mitotic cell cycle;0.0120053386563883!GO:0006405;RNA export from nucleus;0.0127145855611685!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0127145855611685!GO:0009109;coenzyme catabolic process;0.0127512598687987!GO:0006952;defense response;0.0131052487208794!GO:0030027;lamellipodium;0.0134442623925021!GO:0030100;regulation of endocytosis;0.0134442623925021!GO:0033367;protein localization in mast cell secretory granule;0.0134442623925021!GO:0033365;protein localization in organelle;0.0134442623925021!GO:0033371;T cell secretory granule organization and biogenesis;0.0134442623925021!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0134442623925021!GO:0033375;protease localization in T cell secretory granule;0.0134442623925021!GO:0042629;mast cell granule;0.0134442623925021!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0134442623925021!GO:0033364;mast cell secretory granule organization and biogenesis;0.0134442623925021!GO:0033380;granzyme B localization in T cell secretory granule;0.0134442623925021!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0134442623925021!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0134442623925021!GO:0033368;protease localization in mast cell secretory granule;0.0134442623925021!GO:0033366;protein localization in secretory granule;0.0134442623925021!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0134442623925021!GO:0033374;protein localization in T cell secretory granule;0.0134442623925021!GO:0030218;erythrocyte differentiation;0.0136897511360421!GO:0002440;production of molecular mediator of immune response;0.0139341063529498!GO:0030176;integral to endoplasmic reticulum membrane;0.0139763020857379!GO:0002520;immune system development;0.014111947237264!GO:0030503;regulation of cell redox homeostasis;0.014111947237264!GO:0005048;signal sequence binding;0.0141133892221954!GO:0006458;'de novo' protein folding;0.0141225590463445!GO:0051084;'de novo' posttranslational protein folding;0.0141225590463445!GO:0045576;mast cell activation;0.0143751909744645!GO:0030041;actin filament polymerization;0.0144538171940067!GO:0002521;leukocyte differentiation;0.0145051366890338!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0147238392724192!GO:0045047;protein targeting to ER;0.0147238392724192!GO:0007259;JAK-STAT cascade;0.0150851640992099!GO:0051252;regulation of RNA metabolic process;0.0150977089748525!GO:0015036;disulfide oxidoreductase activity;0.0151388255559984!GO:0032318;regulation of Ras GTPase activity;0.0153190026179493!GO:0017166;vinculin binding;0.0153867236627481!GO:0003690;double-stranded DNA binding;0.0156812893241596!GO:0019220;regulation of phosphate metabolic process;0.0158666059619614!GO:0051174;regulation of phosphorus metabolic process;0.0158666059619614!GO:0008139;nuclear localization sequence binding;0.0159366367438397!GO:0046467;membrane lipid biosynthetic process;0.0161852943741998!GO:0035035;histone acetyltransferase binding;0.0166911933136734!GO:0000287;magnesium ion binding;0.0167954998712197!GO:0006355;regulation of transcription, DNA-dependent;0.0170402883554121!GO:0046914;transition metal ion binding;0.0170977099052434!GO:0048471;perinuclear region of cytoplasm;0.0173389668738319!GO:0042613;MHC class II protein complex;0.0176256043703521!GO:0030663;COPI coated vesicle membrane;0.0177780886822618!GO:0030126;COPI vesicle coat;0.0177780886822618!GO:0051098;regulation of binding;0.0179385515469712!GO:0000209;protein polyubiquitination;0.0179497917495869!GO:0030867;rough endoplasmic reticulum membrane;0.0180506757161117!GO:0051049;regulation of transport;0.0180506757161117!GO:0030658;transport vesicle membrane;0.018170950913397!GO:0016311;dephosphorylation;0.0182140562695392!GO:0046466;membrane lipid catabolic process;0.0182181548172038!GO:0004177;aminopeptidase activity;0.0182181548172038!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.019107668018179!GO:0050811;GABA receptor binding;0.0194675954260655!GO:0043621;protein self-association;0.0195396079893178!GO:0048534;hemopoietic or lymphoid organ development;0.0197071648356017!GO:0030118;clathrin coat;0.0200815318025096!GO:0032763;regulation of mast cell cytokine production;0.0200815318025096!GO:0032762;mast cell cytokine production;0.0200815318025096!GO:0005815;microtubule organizing center;0.020569924075588!GO:0000339;RNA cap binding;0.0206059694212716!GO:0043022;ribosome binding;0.0206059694212716!GO:0043299;leukocyte degranulation;0.0207417318054423!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0209908158527315!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0209908158527315!GO:0030133;transport vesicle;0.0213773638430916!GO:0019882;antigen processing and presentation;0.0214452134814369!GO:0043300;regulation of leukocyte degranulation;0.0217628823302222!GO:0019079;viral genome replication;0.0219276558378839!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0219276558378839!GO:0051345;positive regulation of hydrolase activity;0.0224972387564818!GO:0015631;tubulin binding;0.0226662005827344!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0230201748057443!GO:0002443;leukocyte mediated immunity;0.0230201748057443!GO:0006689;ganglioside catabolic process;0.0236146045082128!GO:0030137;COPI-coated vesicle;0.0238815455552529!GO:0003725;double-stranded RNA binding;0.0248962215297839!GO:0051101;regulation of DNA binding;0.0250310587960744!GO:0019843;rRNA binding;0.0251011648355066!GO:0051091;positive regulation of transcription factor activity;0.0252797757967984!GO:0008312;7S RNA binding;0.0253499919792279!GO:0019318;hexose metabolic process;0.0255912745083172!GO:0008361;regulation of cell size;0.026211057792837!GO:0033673;negative regulation of kinase activity;0.0262950067138238!GO:0006469;negative regulation of protein kinase activity;0.0262950067138238!GO:0005694;chromosome;0.0263670387229848!GO:0050900;leukocyte migration;0.0263889016690078!GO:0051050;positive regulation of transport;0.0264679616202955!GO:0006516;glycoprotein catabolic process;0.0269612700558439!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0272204818811154!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0272204818811154!GO:0048146;positive regulation of fibroblast proliferation;0.0275399834344042!GO:0008637;apoptotic mitochondrial changes;0.0276118023126951!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0276118023126951!GO:0002821;positive regulation of adaptive immune response;0.0276118023126951!GO:0051059;NF-kappaB binding;0.0276118023126951!GO:0002718;regulation of cytokine production during immune response;0.0276118023126951!GO:0002367;cytokine production during immune response;0.0276118023126951!GO:0002700;regulation of production of molecular mediator of immune response;0.0276118023126951!GO:0043488;regulation of mRNA stability;0.0289705252758302!GO:0043487;regulation of RNA stability;0.0289705252758302!GO:0006650;glycerophospholipid metabolic process;0.0290818834880982!GO:0045792;negative regulation of cell size;0.0293123823846868!GO:0035258;steroid hormone receptor binding;0.0294689815283267!GO:0008624;induction of apoptosis by extracellular signals;0.029757608047113!GO:0000785;chromatin;0.0297952314028808!GO:0051348;negative regulation of transferase activity;0.0298694290505621!GO:0002224;toll-like receptor signaling pathway;0.0299365808913199!GO:0002221;pattern recognition receptor signaling pathway;0.0299365808913199!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0300282618790748!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0308861828197441!GO:0008286;insulin receptor signaling pathway;0.0314219287262649!GO:0000278;mitotic cell cycle;0.0315331729558302!GO:0000049;tRNA binding;0.0322598014230025!GO:0005996;monosaccharide metabolic process;0.0324734242242464!GO:0006914;autophagy;0.0327184894186625!GO:0009611;response to wounding;0.032836461867454!GO:0002467;germinal center formation;0.0329276986893453!GO:0002250;adaptive immune response;0.033045157449134!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.033045157449134!GO:0051056;regulation of small GTPase mediated signal transduction;0.0331804891242431!GO:0048144;fibroblast proliferation;0.0335504994458917!GO:0048145;regulation of fibroblast proliferation;0.0335504994458917!GO:0042348;NF-kappaB import into nucleus;0.0335504994458917!GO:0042345;regulation of NF-kappaB import into nucleus;0.0335504994458917!GO:0030433;ER-associated protein catabolic process;0.0339121265242042!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0339121265242042!GO:0030984;kininogen binding;0.0340256023513942!GO:0004213;cathepsin B activity;0.0340256023513942!GO:0006007;glucose catabolic process;0.035291837732578!GO:0050681;androgen receptor binding;0.0358114498412681!GO:0051347;positive regulation of transferase activity;0.0364035617042132!GO:0006984;ER-nuclear signaling pathway;0.0369817462734246!GO:0030522;intracellular receptor-mediated signaling pathway;0.0371759025026333!GO:0032760;positive regulation of tumor necrosis factor production;0.0371759025026333!GO:0051085;chaperone cofactor-dependent protein folding;0.0372165947735121!GO:0000118;histone deacetylase complex;0.0372254466311127!GO:0030308;negative regulation of cell growth;0.0372685087866249!GO:0000119;mediator complex;0.0372685087866249!GO:0030660;Golgi-associated vesicle membrane;0.0373197637014442!GO:0000738;DNA catabolic process, exonucleolytic;0.0373261421256282!GO:0006354;RNA elongation;0.0376572507322397!GO:0004563;beta-N-acetylhexosaminidase activity;0.0378370640375502!GO:0002697;regulation of immune effector process;0.038024307511194!GO:0006376;mRNA splice site selection;0.0382140710919198!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0382140710919198!GO:0031327;negative regulation of cellular biosynthetic process;0.0383150858705747!GO:0000165;MAPKKK cascade;0.0383150858705747!GO:0033033;negative regulation of myeloid cell apoptosis;0.0383150858705747!GO:0001803;regulation of type III hypersensitivity;0.0383150858705747!GO:0032733;positive regulation of interleukin-10 production;0.0383150858705747!GO:0033025;regulation of mast cell apoptosis;0.0383150858705747!GO:0001805;positive regulation of type III hypersensitivity;0.0383150858705747!GO:0033023;mast cell homeostasis;0.0383150858705747!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0383150858705747!GO:0033032;regulation of myeloid cell apoptosis;0.0383150858705747!GO:0001802;type III hypersensitivity;0.0383150858705747!GO:0033028;myeloid cell apoptosis;0.0383150858705747!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0383150858705747!GO:0033026;negative regulation of mast cell apoptosis;0.0383150858705747!GO:0033024;mast cell apoptosis;0.0383150858705747!GO:0005905;coated pit;0.0387821525711136!GO:0045639;positive regulation of myeloid cell differentiation;0.0394199212769265!GO:0006644;phospholipid metabolic process;0.039874054031784!GO:0045603;positive regulation of endothelial cell differentiation;0.0402934764687563!GO:0046578;regulation of Ras protein signal transduction;0.0403004801683116!GO:0009306;protein secretion;0.0403004801683116!GO:0006465;signal peptide processing;0.0403082345155338!GO:0019058;viral infectious cycle;0.0407409577018695!GO:0008538;proteasome activator activity;0.0408765595009933!GO:0045309;protein phosphorylated amino acid binding;0.0409266019658747!GO:0017091;AU-rich element binding;0.0410206331603785!GO:0050779;RNA destabilization;0.0410206331603785!GO:0000289;poly(A) tail shortening;0.0410206331603785!GO:0030119;AP-type membrane coat adaptor complex;0.0416831451955361!GO:0008017;microtubule binding;0.0432117819183968!GO:0051920;peroxiredoxin activity;0.0432304837372659!GO:0002448;mast cell mediated immunity;0.0432304837372659!GO:0043303;mast cell degranulation;0.0432304837372659!GO:0033549;MAP kinase phosphatase activity;0.0432304837372659!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0432304837372659!GO:0042147;retrograde transport, endosome to Golgi;0.0438681268624978!GO:0015923;mannosidase activity;0.0449396031117748!GO:0002237;response to molecule of bacterial origin;0.0450906329278906!GO:0048872;homeostasis of number of cells;0.0452880895750606!GO:0045646;regulation of erythrocyte differentiation;0.0452880895750606!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0455339165033034!GO:0007006;mitochondrial membrane organization and biogenesis;0.045565517494368!GO:0005684;U2-dependent spliceosome;0.045565517494368!GO:0006414;translational elongation;0.045565517494368!GO:0004860;protein kinase inhibitor activity;0.0461116702822221!GO:0006509;membrane protein ectodomain proteolysis;0.0462510647610959!GO:0033619;membrane protein proteolysis;0.0462510647610959!GO:0043304;regulation of mast cell degranulation;0.0462814173960719!GO:0008320;protein transmembrane transporter activity;0.0462814173960719!GO:0003711;transcription elongation regulator activity;0.046540861662954!GO:0005869;dynactin complex;0.046540861662954!GO:0005669;transcription factor TFIID complex;0.046613712671159!GO:0019783;small conjugating protein-specific protease activity;0.0470338308905499!GO:0030258;lipid modification;0.0470924881704691!GO:0012506;vesicle membrane;0.0473671015009981!GO:0005788;endoplasmic reticulum lumen;0.0475172268166275!GO:0051881;regulation of mitochondrial membrane potential;0.0480950184092526!GO:0030384;phosphoinositide metabolic process;0.0482760734944699!GO:0045113;regulation of integrin biosynthetic process;0.0499523728868442!GO:0045112;integrin biosynthetic process;0.0499523728868442!GO:0043681;protein import into mitochondrion;0.0499523728868442 | |||
|sample_id=11877 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=SREBF1,2:3.35571885008;NFE2L2:3.22094872512;NFE2:3.20640941952;FOSL2:2.71213982929;PAX2:2.68677608159;BACH2:2.55979684925;NR1H4:2.55875677879;SPI1:2.52695481325;CEBPA,B_DDIT3:2.36514746424;SPIB:2.36254628951;FOS_FOS{B,L1}_JUN{B,D}:2.25463107449;HLF:2.10627350458;ATF5_CREB3:2.10599775689;FOXP3:2.02891568985;ETS1,2:2.01239328253;DMAP1_NCOR{1,2}_SMARC:1.85167205446;NFIL3:1.82132524578;NFE2L1:1.72833261118;EP300:1.70034739069;ATF4:1.68450750875;NFKB1_REL_RELA:1.63335160711;RUNX1..3:1.50357559211;ATF6:1.48013152715;NANOG{mouse}:1.44038631328;TLX2:1.34795067656;SMAD1..7,9:1.34615988766;JUN:1.31434887096;HMX1:1.23860701987;ELF1,2,4:1.22552430623;FOXN1:1.21566648707;HES1:1.21028770118;MAFB:1.11871189642;CREB1:1.10257342247;PDX1:1.06370230554;RXRA_VDR{dimer}:1.05699179284;ESR1:1.00183700182;TFCP2:0.918537622545;GLI1..3:0.914050435032;IRF1,2:0.888684576056;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.824160139563;HSF1,2:0.803377015684;ALX4:0.789250719679;ESRRA:0.769322174113;CDX1,2,4:0.716921924442;TGIF1:0.705582436986;IRF7:0.657567509177;NR6A1:0.614822654463;ATF2:0.605473507589;FOX{F1,F2,J1}:0.572264474707;NANOG:0.478596132736;STAT2,4,6:0.429746228966;PITX1..3:0.389400143058;PAX3,7:0.34428047001;FOXD3:0.33263816538;PPARG:0.30253102963;HIF1A:0.270808830769;FOXO1,3,4:0.24321826197;SPZ1:0.13654632075;ZBTB16:0.0946464977379;ALX1:0.0752256289819;PRDM1:0.0632690064913;EN1,2:0.0564161125318;TBP:0.0557409359882;FOX{D1,D2}:0.0506627201315;IKZF2:0.0452122886752;PAX4:0.0268948452767;AHR_ARNT_ARNT2:0.0265852570901;HMGA1,2:0.0205912145192;NFIX:0.019572841109;RFX2..5_RFXANK_RFXAP:0.0152490851961;BPTF:-0.0424472843737;HOX{A5,B5}:-0.0855055960416;EGR1..3:-0.086537970725;NFATC1..3:-0.0949440321113;MYB:-0.0971713864406;GATA4:-0.158080339636;OCT4_SOX2{dimer}:-0.183747807437;RREB1:-0.199672892102;FOXP1:-0.213541087968;PAX1,9:-0.217987933713;ZBTB6:-0.251729052928;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.263766889471;XBP1:-0.267848363459;TFAP4:-0.313170764142;NKX3-1:-0.335177361863;MYFfamily:-0.335299751154;SRF:-0.344415501508;HNF4A_NR2F1,2:-0.373949086535;GCM1,2:-0.40079404354;ZNF148:-0.414633072907;MZF1:-0.419842071877;PATZ1:-0.430000875753;RXR{A,B,G}:-0.487924139479;MEF2{A,B,C,D}:-0.50537839096;GZF1:-0.51503072886;ZIC1..3:-0.53000193386;TBX4,5:-0.530152122275;HBP1_HMGB_SSRP1_UBTF:-0.557562075888;REST:-0.557784509764;IKZF1:-0.618102160433;HNF1A:-0.633482464358;PRRX1,2:-0.644113033127;SOX2:-0.645310323381;NHLH1,2:-0.666202537126;STAT5{A,B}:-0.742712915119;NKX6-1,2:-0.75520719469;HOXA9_MEIS1:-0.783451931405;STAT1,3:-0.784087065957;RBPJ:-0.799855219229;AIRE:-0.81340513696;ZNF238:-0.833517806748;MTF1:-0.851117547365;FOXM1:-0.868872157357;T:-0.8737841687;POU5F1:-0.875800553427;CUX2:-0.882786814955;MYOD1:-0.933193196958;TFAP2{A,C}:-0.935787334047;GATA6:-0.945139540719;PAX6:-0.964723175767;ZFP161:-0.965349414005;MED-1{core}:-0.974386592194;UFEwm:-0.980737196325;TAL1_TCF{3,4,12}:-0.984409201161;TOPORS:-0.987749600679;EVI1:-0.990365116999;KLF4:-0.998187305019;MTE{core}:-1.00190068231;TFAP2B:-1.0026686243;SOX5:-1.0051406078;NKX2-1,4:-1.01420533059;POU2F1..3:-1.0227959468;PAX8:-1.04901670223;NKX3-2:-1.11462345576;TEF:-1.12154270629;TLX1..3_NFIC{dimer}:-1.13746668836;GTF2A1,2:-1.14698852667;VSX1,2:-1.15946610364;TP53:-1.17880825879;RORA:-1.20402631666;ZEB1:-1.21338961384;NKX2-3_NKX2-5:-1.24933158629;NKX2-2,8:-1.2503603045;EBF1:-1.25320360055;GTF2I:-1.2683624427;TEAD1:-1.28719916665;ELK1,4_GABP{A,B1}:-1.29359680788;FOXL1:-1.29481931831;POU6F1:-1.29793433568;MYBL2:-1.3291928213;ZNF423:-1.33192473334;LMO2:-1.33655503886;DBP:-1.35528951375;CRX:-1.35539536314;PAX5:-1.37123069785;RFX1:-1.37943685654;ONECUT1,2:-1.41199606994;NR5A1,2:-1.42518633201;MAZ:-1.44271468799;SP1:-1.44648704059;TFDP1:-1.45492531666;E2F1..5:-1.46408705306;SNAI1..3:-1.49063354139;XCPE1{core}:-1.50863883242;HOX{A4,D4}:-1.52985875403;HIC1:-1.55786189571;NR3C1:-1.59304400815;AR:-1.60464500317;SOX{8,9,10}:-1.62529407719;ARID5B:-1.63985668122;BREu{core}:-1.66507019443;HAND1,2:-1.68932766721;HOX{A6,A7,B6,B7}:-1.70889054073;ZNF384:-1.74773845768;YY1:-1.88492069995;GFI1B:-1.9509587121;LHX3,4:-1.95684145501;FOXA2:-2.00015633143;FOXQ1:-2.00732788382;POU1F1:-2.05674290982;ADNP_IRX_SIX_ZHX:-2.0913295382;FOX{I1,J2}:-2.11144931475;bHLH_family:-2.13462156464;SOX17:-2.22533389486;CDC5L:-2.23314691591;GFI1:-2.29654023763;NFY{A,B,C}:-2.34009009078;POU3F1..4:-2.35788524106;NRF1:-2.39893489764;PBX1:-2.45660448026;ZNF143:-2.78296775195;LEF1_TCF7_TCF7L1,2:-2.84908814738 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11877-125C5;search_select_hide=table117:FF:11877-125C5 | |||
}} | }} |
Latest revision as of 18:25, 4 June 2020
Name: | CD14+ monocytes - treated with Cryptococcus, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13487 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13487
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13487
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.106 |
10 | 10 | 0.0226 |
100 | 100 | 0.686 |
101 | 101 | 0.843 |
102 | 102 | 0.492 |
103 | 103 | 0.236 |
104 | 104 | 0.574 |
105 | 105 | 0.211 |
106 | 106 | 5.35409e-4 |
107 | 107 | 0.22 |
108 | 108 | 0.928 |
109 | 109 | 0.218 |
11 | 11 | 0.156 |
110 | 110 | 0.282 |
111 | 111 | 0.0696 |
112 | 112 | 0.237 |
113 | 113 | 0.552 |
114 | 114 | 0.0206 |
115 | 115 | 0.307 |
116 | 116 | 0.755 |
117 | 117 | 0.0725 |
118 | 118 | 0.184 |
119 | 119 | 0.111 |
12 | 12 | 0.342 |
120 | 120 | 0.966 |
121 | 121 | 0.315 |
122 | 122 | 0.557 |
123 | 123 | 0.0743 |
124 | 124 | 0.607 |
125 | 125 | 0.599 |
126 | 126 | 0.222 |
127 | 127 | 0.267 |
128 | 128 | 0.0197 |
129 | 129 | 0.391 |
13 | 13 | 0.191 |
130 | 130 | 0.136 |
131 | 131 | 0.569 |
132 | 132 | 0.0612 |
133 | 133 | 0.648 |
134 | 134 | 0.498 |
135 | 135 | 0.435 |
136 | 136 | 0.9 |
137 | 137 | 0.0148 |
138 | 138 | 0.159 |
139 | 139 | 0.0359 |
14 | 14 | 0.506 |
140 | 140 | 0.15 |
141 | 141 | 0.307 |
142 | 142 | 0.53 |
143 | 143 | 0.0155 |
144 | 144 | 0.597 |
145 | 145 | 0.511 |
146 | 146 | 0.481 |
147 | 147 | 0.35 |
148 | 148 | 0.0105 |
149 | 149 | 0.589 |
15 | 15 | 0.145 |
150 | 150 | 0.48 |
151 | 151 | 0.352 |
152 | 152 | 0.119 |
153 | 153 | 0.443 |
154 | 154 | 0.474 |
155 | 155 | 0.351 |
156 | 156 | 0.756 |
157 | 157 | 0.251 |
158 | 158 | 0.044 |
159 | 159 | 0.703 |
16 | 16 | 0.313 |
160 | 160 | 0.352 |
161 | 161 | 0.47 |
162 | 162 | 0.325 |
163 | 163 | 0.229 |
164 | 164 | 0.153 |
165 | 165 | 0.19 |
166 | 166 | 0.447 |
167 | 167 | 0.217 |
168 | 168 | 0.411 |
169 | 169 | 0.0079 |
17 | 17 | 0.184 |
18 | 18 | 0.0924 |
19 | 19 | 0.325 |
2 | 2 | 1 |
20 | 20 | 0.378 |
21 | 21 | 0.379 |
22 | 22 | 0.201 |
23 | 23 | 0.051 |
24 | 24 | 0.308 |
25 | 25 | 0.371 |
26 | 26 | 0.0603 |
27 | 27 | 0.965 |
28 | 28 | 0.379 |
29 | 29 | 0.367 |
3 | 3 | 0.12 |
30 | 30 | 0.632 |
31 | 31 | 0.718 |
32 | 32 | 0.986 |
33 | 33 | 0.44 |
34 | 34 | 0.428 |
35 | 35 | 0.181 |
36 | 36 | 0.177 |
37 | 37 | 0.0592 |
38 | 38 | 0.341 |
39 | 39 | 0.731 |
4 | 4 | 0.633 |
40 | 40 | 0.223 |
41 | 41 | 0.0115 |
42 | 42 | 0.419 |
43 | 43 | 0.0373 |
44 | 44 | 0.774 |
45 | 45 | 0.61 |
46 | 46 | 0.136 |
47 | 47 | 0.48 |
48 | 48 | 0.447 |
49 | 49 | 0.102 |
5 | 5 | 0.246 |
50 | 50 | 0.988 |
51 | 51 | 0.361 |
52 | 52 | 0.275 |
53 | 53 | 0.331 |
54 | 54 | 0.301 |
55 | 55 | 0.339 |
56 | 56 | 0.66 |
57 | 57 | 0.762 |
58 | 58 | 0.113 |
59 | 59 | 0.0993 |
6 | 6 | 0.621 |
60 | 60 | 0.0449 |
61 | 61 | 0.55 |
62 | 62 | 0.0452 |
63 | 63 | 0.486 |
64 | 64 | 0.434 |
65 | 65 | 0.206 |
66 | 66 | 0.323 |
67 | 67 | 0.536 |
68 | 68 | 0.73 |
69 | 69 | 0.953 |
7 | 7 | 0.261 |
70 | 70 | 0.0143 |
71 | 71 | 0.0337 |
72 | 72 | 0.265 |
73 | 73 | 0.117 |
74 | 74 | 0.0897 |
75 | 75 | 0.106 |
76 | 76 | 0.228 |
77 | 77 | 0.34 |
78 | 78 | 0.0979 |
79 | 79 | 0.152 |
8 | 8 | 0.336 |
80 | 80 | 0.207 |
81 | 81 | 0.357 |
82 | 82 | 0.0958 |
83 | 83 | 0.0582 |
84 | 84 | 0.374 |
85 | 85 | 0.00807 |
86 | 86 | 0.039 |
87 | 87 | 0.447 |
88 | 88 | 0.569 |
89 | 89 | 0.16 |
9 | 9 | 0.377 |
90 | 90 | 0.0533 |
91 | 91 | 0.248 |
92 | 92 | 0.173 |
93 | 93 | 0.347 |
94 | 94 | 0.044 |
95 | 95 | 0.373 |
96 | 96 | 0.197 |
97 | 97 | 0.904 |
98 | 98 | 0.113 |
99 | 99 | 0.151 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13487
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011105 human CD14-positive monocytes - treated with Cryptococcus sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000634 (Cryptococcus treatment sample)
0011105 (human CD14-positive monocytes - treated with Cryptococcus sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)