FF:13323-143B2: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004904 | ||
|accession_numbers=CAGE;DRX008598;DRR009470;DRZ000895;DRZ002280;DRZ012245;DRZ013630 | |||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0000255,CL:0000235 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000357,FF:0000086,FF:0000647,FF:0011215 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|donor= donor3 (536_119:Ud_0h) | |||
|expression_enrichment_score=chr11:47400078..47400106,-!p1@SPI1!2.55!352.08!SPI1;;chr2:68592406..68592424,+!p1@PLEK!2.53!341.03!PLEK;;chr12:54778471..54778528,-!p1@ZNF385A!2.30!198.89!ZNF385A;;chr16:85932760..85932775,+!p1@IRF8!2.27!185.84!IRF8;;chr20:39317868..39317884,-!p1@MAFB!2.03!1186.33!MAFB;;chr7:115670804..115670825,-!p1@TFEC!2.02!103.46!TFEC;;chr10:64576105..64576133,-!p1@EGR2!1.85!140.63!EGR2;;chr11:47400062..47400077,-!p2@SPI1!1.78!59.77!SPI1;;chr10:51572408..51572454,+!p3@NCOA4!1.68!258.66!NCOA4;;chr14:75988771..75988826,+!p1@BATF!1.66!59.27!BATF;;chr7:137620684..137620711,-!p4@CREB3L2!1.58!36.66!CREB3L2;;chr7:128577972..128578047,+!p1@IRF5!1.56!54.24!IRF5;;chr11:47279504..47279563,+!p1@NR1H3!1.55!76.34!NR1H3;;chr7:137620650..137620677,-!p3@CREB3L2!1.50!30.64!CREB3L2;;chr19:33793430..33793447,-!p1@CEBPA!1.49!121.55!CEBPA;;chr7:50344289..50344323,+!p1@IKZF1!1.46!28.13!IKZF1;;chr6:106534192..106534224,+!p1@PRDM1!1.37!61.78!PRDM1;;chr10:31288398..31288455,-!p2@ZNF438!1.34!24.11!ZNF438;;chr2:145277640..145277771,-!p1@ZEB2!1.31!255.15!ZEB2;;chr11:47399996..47400014,-!p4@SPI1!1.31!19.59!SPI1;;chr6:41691289..41691312,-!p9@TFEB!1.23!16.07!TFEB;;chr11:47399947..47399961,-!p3@SPI1!1.22!15.57!SPI1;;chr16:79634624..79634642,-!p1@MAF!1.20!57.26!MAF;;chr11:47400045..47400060,-!p6@SPI1!1.18!14.06!SPI1;;chr10:51572339..51572376,+!p4@NCOA4!1.16!30.14!NCOA4;;chr10:31288370..31288393,-!p3@ZNF438!1.16!13.56!ZNF438;;chr16:79634595..79634620,-!p2@MAF!1.15!24.11!MAF;;chr16:67198683..67198698,+!p2@HSF4!1.15!13.06!HSF4;;chr2:70142232..70142251,+!p1@MXD1!1.13!69.81!MXD1;;chr6:106534230..106534254,+!p2@PRDM1!1.13!31.64!PRDM1;;chr19:54041669..54041697,+!p2@ZNF331!1.13!12.56!ZNF331;;chr2:68592394..68592405,+!p2@PLEK!1.12!12.05!PLEK;;chr3:69788576..69788648,+!p1@MITF!1.10!61.28!MITF;;chr7:50343634..50343717,+!p2@IKZF1!1.10!11.55!IKZF1;;chr11:47400032..47400043,-!p5@SPI1!1.10!11.55!SPI1;;chr2:145277882..145277967,-!p3@ZEB2!1.07!18.58!ZEB2;;chr19:49140609..49140643,-!p1@DBP!1.05!58.76!DBP;;chr12:12764995..12765017,+!p3@CREBL2!1.05!14.57!CREBL2;;chr19:50432132..50432217,+!p2@ATF5!1.01!11.05!ATF5;;chr14:75988831..75988847,+!p2@BATF!1.00!9.04!BATF;;chr19:13213954..13214021,-!p4@LYL1!1.00!9.04!LYL1;;chr17:40440481..40440550,+!p1@STAT5A!0.96!60.77!STAT5A;;chr16:79634581..79634592,-!p4@MAF!0.96!8.04!MAF;;chr19:13213662..13213686,-!p1@LYL1!0.94!11.55!LYL1;;chr5:88178983..88179012,-!p1@MEF2C!0.93!60.77!MEF2C;;chr2:113999360..113999386,-!p4@PAX8!0.93!7.53!PAX8;;chr19:35759824..35759891,+!p1@USF2!0.91!233.05!USF2;;chrY:21906594..21906622,-!p1@KDM5D!0.90!7.03!KDM5D;;chr11:128563948..128564003,+!p1@FLI1!0.89!86.39!FLI1;;chrX:131623044..131623089,-!p1@MBNL3!0.89!29.13!MBNL3;;chr9:137217986..137218049,+!p3@RXRA!0.89!20.09!RXRA;;chrY:2803415..2803468,+!p1@ZFY!0.88!6.53!ZFY;;chr12:26277956..26277980,-!p1@BHLHE41!0.87!24.11!BHLHE41;;chr6:44233252..44233296,-!p1@NFKBIE!0.85!64.29!NFKBIE;;chr13:41593425..41593480,-!p1@ELF1!0.85!40.68!ELF1;;chr16:79633894..79633954,-!p3@MAF!0.85!12.05!MAF;;chr2:145275982..145276003,-!p7@ZEB2!0.85!6.03!ZEB2;;chr6:106535598..106535637,+!p7@PRDM1!0.85!6.03!PRDM1;;chr13:27998831..27998851,+!p2@GTF3A!0.84!38.17!GTF3A;;chr18:52989031..52989079,-!p2@TCF4!0.84!14.57!TCF4;;chr12:12764947..12764986,+!p2@CREBL2!0.82!11.55!CREBL2;;chr7:149470641..149470694,-!p1@ZNF467!0.79!25.11!ZNF467;;chr13:27998854..27998866,+!p3@GTF3A!0.79!11.05!GTF3A;;chr19:13213704..13213726,-!p3@LYL1!0.79!7.03!LYL1;;chr16:31885093..31885165,+!p1@ZNF267!0.78!83.37!ZNF267;;chr1:221053049..221053075,+!p3@HLX!0.78!9.04!HLX;;chr1:78050720..78050734,-!p9@ZZZ3!0.78!5.02!ZZZ3;;chr10:94449703..94449718,+!p1@HHEX!0.77!20.59!HHEX;;chr3:185826855..185826911,-!p1@ETV5!0.76!143.14!ETV5;;chr14:62162258..62162269,+!p2@HIF1A!0.76!50.73!HIF1A;;chr19:35759976..35760042,+!p4@USF2!0.76!27.12!USF2;;chr1:25256756..25256774,-!p1@RUNX3!0.76!9.54!RUNX3;;chr2:70167296..70167306,+!p3@MXD1!0.76!7.53!MXD1;;chr3:12330560..12330579,+!p1@PPARG!0.76!5.52!PPARG;;chr16:67198633..67198671,+!p1@HSF4!0.74!4.52!HSF4;;chr22:38597987..38598021,+!p2@MAFF!0.71!28.63!MAFF;;chr3:12329358..12329393,+!p3@PPARG!0.71!11.05!PPARG;;chr1:158979792..158979814,+!p2@IFI16!0.70!43.19!IFI16;;chr14:62203595..62203676,+!p4@HIF1A!0.70!8.04!HIF1A;;chr12:26277929..26277955,-!p3@BHLHE41!0.70!6.03!BHLHE41;;chr6:144385698..144385742,-!p2@PLAGL1!0.70!5.02!PLAGL1;;chr18:52989001..52989030,-!p10@TCF4!0.70!4.52!TCF4;;chr10:3827371..3827386,-!p2@KLF6!0.68!36.16!KLF6;;chr5:321810..321877,+!p1@AHRR!0.68!13.56!AHRR;;chr1:158979872..158979898,+!p3@IFI16!0.68!13.06!IFI16;;chr19:42636586..42636607,-!p1@POU2F2!0.68!11.55!POU2F2;;chr19:45252008..45252024,+!p2@BCL3!0.67!13.56!BCL3;;chr2:113057415..113057477,+!p3@ZC3H6!0.67!5.02!ZC3H6;;chr14:89628064..89628109,-!p4@FOXN3!0.66!8.04!FOXN3;;chr14:75745523..75745537,+!p1@FOS!0.65!484.68!FOS;;chr5:76383017..76383068,-!p1@ZBED3!0.65!14.57!ZBED3;;chr10:94449675..94449694,+!p2@HHEX!0.65!10.55!HHEX;;chr2:145282041..145282092,-!p8@ZEB2!0.65!5.52!ZEB2;;chr2:145275947..145275981,-!p10@ZEB2!0.65!3.52!ZEB2;;chr19:35760698..35760738,+!p8@USF2!0.65!3.52!USF2;;chr10:60144869..60144887,+!p3@TFAM!0.65!3.52!TFAM;;chr1:25256439..25256476,-!p3@RUNX3!0.65!3.52!RUNX3;;chr1:158979686..158979745,+!p1@IFI16!0.64!132.09!IFI16;;chr2:61108695..61108753,+!p1@REL!0.64!27.12!REL;;chr12:54785074..54785122,-!p2@ZNF385A!0.64!5.52!ZNF385A;;chr14:35872453..35872485,-!p2@NFKBIA!0.63!9.04!NFKBIA;;chr18:51690935..51690957,-!p8@MBD2!0.63!5.02!MBD2;;chr7:28725715..28725727,+!p3@CREB5!0.63!4.02!CREB5;;chr10:35484804..35484902,+!p2@CREM!0.62!14.06!CREM;;chr19:49140572..49140594,-!p2@DBP!0.62!5.52!DBP;;chr5:88179195..88179224,-!p3@MEF2C!0.62!5.52!MEF2C;;chr16:73093174..73093209,-!p3@ZFHX3!0.62!4.52!ZFHX3;;chr14:35873947..35873965,-!p1@NFKBIA!0.61!238.57!NFKBIA;;chr14:68283291..68283323,-!p1@ZFYVE26!0.61!61.28!ZFYVE26;;chr2:97202480..97202499,+!p1@ARID5A!0.61!37.17!ARID5A;;chr1:221052776..221052799,+!p1@HLX!0.61!6.03!HLX;;chr8:71316428..71316459,-!p2@NCOA2!0.60!5.52!NCOA2;;chr19:49140595..49140607,-!p3@DBP!0.60!4.52!DBP;;chr3:101546827..101546847,+!p2@NFKBIZ!0.60!4.52!NFKBIZ;;chr2:122042770..122042785,-!p1@TFCP2L1!0.60!3.01!TFCP2L1;;chr19:13213399..13213414,-!p6@LYL1!0.60!3.01!LYL1;;chr19:54058073..54058088,+!p1@ZNF331!0.60!3.01!ZNF331;;chr11:47279491..47279502,+!p6@NR1H3!0.60!3.01!NR1H3;;chr14:62214151..62214164,+!p11@HIF1A!0.60!3.01!HIF1A;;chr18:77160282..77160343,+!p2@NFATC1!0.59!21.60!NFATC1;;chr4:87968203..87968221,+!p11@AFF1!0.58!5.02!AFF1;;chr8:48650715..48650735,-!p1@CEBPD!0.57!432.44!CEBPD;;chr6:34204973..34204990,+!p4@HMGA1!0.57!44.70!HMGA1;;chr3:48282587..48282603,+!p1@ZNF589!0.57!14.57!ZNF589;;chr18:74207147..74207183,-!p1@ZNF516!0.57!9.54!ZNF516;;chr3:5021113..5021180,+!p1@BHLHE40!0.56!234.05!BHLHE40;;chr19:926001..926046,+!p1@ARID3A!0.56!11.05!ARID3A;;chr15:90544532..90544563,+!p1@ZNF710!0.56!6.03!ZNF710;;chr12:12764773..12764852,+!p1@CREBL2!0.55!80.86!CREBL2;;chr8:22550982..22550999,-!p1@EGR3!0.55!8.54!EGR3;;chr14:35872962..35873025,-!p3@NFKBIA!0.55!7.53!NFKBIA;;chr18:3449527..3449582,+!p6@TGIF1!0.55!5.52!TGIF1;;chr6:44232765..44232778,-!p5@NFKBIE!0.55!2.51!NFKBIE;;chr7:50344251..50344288,+!p3@IKZF1!0.55!2.51!IKZF1;;chr1:158985686..158985719,+!p15@IFI16!0.55!2.51!IFI16;;chr20:3321190..3321215,-!p7@C20orf194!0.55!2.51!C20orf194;;chrY:21906761..21906810,-!p2@KDM5D!0.55!2.51!KDM5D;;chr11:47399920..47399931,-!p7@SPI1!0.55!2.51!SPI1;;chr2:145277620..145277627,-!p19@ZEB2!0.55!2.51!ZEB2;;chr2:231090433..231090469,+!p1@SP140!0.55!2.51!SP140;;chr2:238600998..238601013,+!p5@LRRFIP1!0.55!2.51!LRRFIP1;;chr14:74226747..74226779,-!p3@C14orf43!0.54!17.08!C14orf43;;chr14:74226783..74226819,-!p4@C14orf43!0.54!15.07!C14orf43;;chr5:88179017..88179046,-!p2@MEF2C!0.54!12.05!MEF2C;;chr8:116681123..116681143,-!p4@TRPS1!0.54!5.52!TRPS1;;chr16:73092791..73092831,-!p4@ZFHX3!0.54!5.02!ZFHX3;;chr4:87857433..87857472,+!p9@AFF1!0.54!5.02!AFF1;;chr1:212782094..212782109,+!p1@ATF3!0.53!83.88!ATF3;;chr4:87856129..87856186,+!p1@AFF1!0.53!42.69!AFF1;;chr11:615570..615721,-!p2@IRF7!0.53!5.52!IRF7;;chr12:26277817..26277863,-!p2@BHLHE41!0.53!3.52!BHLHE41;;chr8:116681194..116681214,-!p1@TRPS1!0.52!27.62!TRPS1;;chr7:17338324..17338341,+!p3@AHR!0.52!9.54!AHR;;chr19:926055..926068,+!p2@ARID3A!0.52!6.03!ARID3A;;chr8:116680215..116680245,-!p6@TRPS1!0.52!4.02!TRPS1;;chr7:17369649..17369664,+!p4@AHR!0.52!3.01!AHR;;chr7:139762641..139762768,-!p1@PARP12!0.51!39.68!PARP12;;chr2:238600933..238600985,+!p3@LRRFIP1!0.51!15.57!LRRFIP1;;chr12:11802753..11802834,+!p2@ETV6!0.51!14.06!ETV6;;chr4:185395633..185395651,-!p2@IRF2!0.51!4.02!IRF2;;chr7:100076723..100076737,-!p3@TSC22D4!0.51!4.02!TSC22D4;;chr14:62193465..62193490,+!p7@HIF1A!0.51!3.52!HIF1A;;chr2:8822176..8822196,+!p1@ID2!0.50!403.31!ID2;;chrX:129244454..129244488,-!p1@ELF4!0.50!20.09!ELF4;;chr5:137804484..137804498,+!p2@EGR1!0.50!11.05!EGR1;;chr4:87928328..87928351,+!p6@AFF1!0.50!7.03!AFF1;;chr19:36391434..36391450,-!p1@NFKBID!0.50!5.02!NFKBID;;chr2:74730430..74730451,-!p1@LBX2!0.50!4.02!LBX2;;chr1:221052733..221052749,+!p2@HLX!0.50!3.01!HLX;;chr19:12902289..12902307,+!p1@JUNB!0.49!646.40!JUNB;;chr4:103422499..103422632,+!p1@NFKB1!0.49!58.76!NFKB1;;chr2:10183651..10183713,+!p1@KLF11!0.49!20.09!KLF11;;chr6:41703296..41703367,-!p1@TFEB!0.49!13.56!TFEB;;chr19:11998584..11998649,+!p1@ZNF69!0.49!12.05!ZNF69;;chr1:249132556..249132573,+!p3@ZNF672!0.49!7.53!ZNF672;;chr16:68118689..68118733,+!p3@NFATC3!0.49!6.53!NFATC3;;chr10:3824229..3824253,-!p7@KLF6!0.49!2.51!KLF6;;chr7:17338266..17338282,+!p1@AHR!0.48!29.13!AHR;;chr19:22235279..22235301,+!p1@ZNF257!0.48!4.52!ZNF257;;chr2:28618532..28618610,+!p4@FOSL2!0.48!4.02!FOSL2;;chr2:61108771..61108789,+!p4@REL!0.48!3.52!REL;;chr14:62203749..62203798,+!p5@HIF1A!0.48!3.52!HIF1A;;chr1:158985493..158985535,+!p4@IFI16!0.48!3.52!IFI16;;chr7:27835758..27835772,+!p3@TAX1BP1!0.48!3.01!TAX1BP1;;chr19:37958404..37958434,+!p2@ZNF570!0.48!3.01!ZNF570;;chr1:221052994..221053008,+!p6@HLX!0.48!2.51!HLX;;chr1:221052669..221052678,+!p12@HLX!0.48!2.01!HLX;;chr21:30672433..30672464,+!p6@BACH1!0.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000235;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 42: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Monocyte-derived%2520macrophages%2520response%2520to%2520udorn%2520influenza%2520infection%252c%252000hr00min%252c%2520donor3%2520%2528536_119%253aUd_0h%2529.CNhs13650.13323-143B2.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Monocyte-derived%2520macrophages%2520response%2520to%2520udorn%2520influenza%2520infection%252c%252000hr00min%252c%2520donor3%2520%2528536_119%253aUd_0h%2529.CNhs13650.13323-143B2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Monocyte-derived%2520macrophages%2520response%2520to%2520udorn%2520influenza%2520infection%252c%252000hr00min%252c%2520donor3%2520%2528536_119%253aUd_0h%2529.CNhs13650.13323-143B2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Monocyte-derived%2520macrophages%2520response%2520to%2520udorn%2520influenza%2520infection%252c%252000hr00min%252c%2520donor3%2520%2528536_119%253aUd_0h%2529.CNhs13650.13323-143B2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Monocyte-derived%2520macrophages%2520response%2520to%2520udorn%2520influenza%2520infection%252c%252000hr00min%252c%2520donor3%2520%2528536_119%253aUd_0h%2529.CNhs13650.13323-143B2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:13323-143B2 | |||
|is_a=EFO:0002091;;FF:0011215 | |||
|is_obsolete= | |||
|library_id=CNhs13650 | |||
|library_id_phase_based=2:CNhs13650 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;13323 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;13323 | |||
|name=Monocyte-derived macrophages response to udorn influenza infection | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan= | |||
|profile_hcage=CNhs13650,LSID1059,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq= | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=143 | |||
|rna_catalog_number= | |||
|rna_concentration=318.22 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=0.74 | |||
|rna_od260/280=0.49 | |||
|rna_position=B2 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=143B2 | |||
|rna_weight_ug=9.55 | |||
|sample_age=adult | |||
|sample_category=time courses | |||
|sample_cell_catalog= | |||
|sample_cell_line=Primary | |||
|sample_cell_lot= | |||
|sample_cell_type=HMDM | |||
|sample_collaboration=Baillie/Tomoiu/Fisher/Hume | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=Healthy | |||
|sample_donor(cell lot)=Subject_number_536_119 | |||
|sample_ethnicity=Caucasian | |||
|sample_experimental_condition=Ud 0h | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.28966482851438e-239!GO:0005737;cytoplasm;9.11814830399179e-168!GO:0043227;membrane-bound organelle;1.31134496705062e-146!GO:0043231;intracellular membrane-bound organelle;3.35330343305647e-146!GO:0044444;cytoplasmic part;3.10747819009812e-141!GO:0043226;organelle;3.93384874980203e-131!GO:0043229;intracellular organelle;2.02819369849347e-130!GO:0044422;organelle part;1.23998199935654e-108!GO:0044446;intracellular organelle part;1.05283663754295e-106!GO:0032991;macromolecular complex;9.0022733866679e-78!GO:0044237;cellular metabolic process;7.83121945836569e-75!GO:0044238;primary metabolic process;8.05116769225141e-72!GO:0005739;mitochondrion;9.01190738689708e-72!GO:0030529;ribonucleoprotein complex;1.14317876915809e-63!GO:0043170;macromolecule metabolic process;3.27016186604457e-59!GO:0031090;organelle membrane;1.07379872928932e-58!GO:0003723;RNA binding;5.55244874839763e-55!GO:0043233;organelle lumen;4.38817490256799e-53!GO:0031974;membrane-enclosed lumen;4.38817490256799e-53!GO:0044429;mitochondrial part;7.43844324131495e-50!GO:0009058;biosynthetic process;1.94122244642351e-48!GO:0006412;translation;1.25573201534261e-47!GO:0044428;nuclear part;2.11936642017279e-47!GO:0019538;protein metabolic process;8.494168057668e-47!GO:0033036;macromolecule localization;1.29551461545264e-45!GO:0015031;protein transport;4.57762753493048e-45!GO:0005515;protein binding;4.59916850036913e-45!GO:0045184;establishment of protein localization;3.04514455250935e-44!GO:0044260;cellular macromolecule metabolic process;1.87465727265846e-43!GO:0008104;protein localization;4.11654511432448e-43!GO:0031967;organelle envelope;1.75082928292396e-42!GO:0044267;cellular protein metabolic process;1.79682351729504e-42!GO:0009059;macromolecule biosynthetic process;2.61166556692882e-42!GO:0031975;envelope;3.83256768480629e-42!GO:0044249;cellular biosynthetic process;1.50290023658436e-41!GO:0043234;protein complex;5.17938079592547e-41!GO:0005840;ribosome;2.0242235266482e-39!GO:0005829;cytosol;8.05854312490157e-36!GO:0005634;nucleus;9.05957613641938e-35!GO:0003735;structural constituent of ribosome;4.40331415220118e-34!GO:0005740;mitochondrial envelope;4.93962739003341e-34!GO:0006396;RNA processing;5.99518817069761e-34!GO:0031966;mitochondrial membrane;5.78078327468736e-32!GO:0033279;ribosomal subunit;1.45064178642834e-31!GO:0046907;intracellular transport;4.9945114618866e-31!GO:0006886;intracellular protein transport;2.35523118146692e-29!GO:0019866;organelle inner membrane;4.22334418742667e-29!GO:0016071;mRNA metabolic process;8.93663228664605e-29!GO:0031981;nuclear lumen;9.18501573502689e-28!GO:0005743;mitochondrial inner membrane;1.68405198776462e-27!GO:0016043;cellular component organization and biogenesis;3.2158188108756e-27!GO:0006119;oxidative phosphorylation;3.11778343419548e-26!GO:0065003;macromolecular complex assembly;4.98737894779375e-26!GO:0008380;RNA splicing;5.14903366667718e-26!GO:0006397;mRNA processing;1.00922906343447e-24!GO:0051649;establishment of cellular localization;2.34248967975379e-24!GO:0051641;cellular localization;1.03716185169452e-23!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.33750454148462e-23!GO:0043283;biopolymer metabolic process;1.89731715525165e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.32524821478427e-23!GO:0022607;cellular component assembly;4.75835366244124e-22!GO:0051186;cofactor metabolic process;6.74597529336405e-22!GO:0005773;vacuole;1.29281623759478e-21!GO:0012505;endomembrane system;1.45416095735099e-21!GO:0010467;gene expression;3.66571919646851e-21!GO:0044445;cytosolic part;1.01225280858554e-20!GO:0044455;mitochondrial membrane part;1.98303716141458e-20!GO:0000323;lytic vacuole;3.08101809069617e-20!GO:0005764;lysosome;3.08101809069617e-20!GO:0048770;pigment granule;1.72401831473185e-19!GO:0042470;melanosome;1.72401831473185e-19!GO:0005681;spliceosome;4.01617362065638e-19!GO:0031980;mitochondrial lumen;6.27002127577052e-19!GO:0005759;mitochondrial matrix;6.27002127577052e-19!GO:0012501;programmed cell death;8.70875486769311e-19!GO:0006915;apoptosis;9.7564894001285e-19!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.61998801193822e-18!GO:0044248;cellular catabolic process;3.46423202137579e-18!GO:0005654;nucleoplasm;6.66662862652012e-18!GO:0008219;cell death;9.58196989658371e-18!GO:0016265;death;9.58196989658371e-18!GO:0006732;coenzyme metabolic process;1.25065882858941e-17!GO:0005746;mitochondrial respiratory chain;1.25065882858941e-17!GO:0022618;protein-RNA complex assembly;1.2745711468733e-17!GO:0016192;vesicle-mediated transport;1.32314943184768e-17!GO:0005783;endoplasmic reticulum;2.69292510559975e-17!GO:0015935;small ribosomal subunit;4.08332099634106e-17!GO:0006996;organelle organization and biogenesis;5.56884069395134e-17!GO:0044265;cellular macromolecule catabolic process;5.8088622037066e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.29335611471522e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.52017751907855e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;2.85734631418787e-16!GO:0016462;pyrophosphatase activity;2.98709101186019e-16!GO:0050136;NADH dehydrogenase (quinone) activity;9.66036019499254e-16!GO:0003954;NADH dehydrogenase activity;9.66036019499254e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;9.66036019499254e-16!GO:0044432;endoplasmic reticulum part;9.66036019499254e-16!GO:0015934;large ribosomal subunit;1.42548183771045e-15!GO:0005794;Golgi apparatus;1.45735430717003e-15!GO:0000166;nucleotide binding;2.49801142897187e-15!GO:0017111;nucleoside-triphosphatase activity;3.37628444059354e-15!GO:0009057;macromolecule catabolic process;8.06707010092736e-15!GO:0006259;DNA metabolic process;8.71654648287407e-15!GO:0006457;protein folding;9.4565712210517e-15!GO:0043285;biopolymer catabolic process;1.32069185434882e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.34256449794517e-14!GO:0000502;proteasome complex (sensu Eukaryota);1.35025168824874e-14!GO:0016874;ligase activity;1.58219559966605e-14!GO:0006605;protein targeting;2.67246548441806e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.39945184651076e-14!GO:0042773;ATP synthesis coupled electron transport;3.39945184651076e-14!GO:0044451;nucleoplasm part;4.52816281962514e-14!GO:0030964;NADH dehydrogenase complex (quinone);5.51343322585193e-14!GO:0045271;respiratory chain complex I;5.51343322585193e-14!GO:0005747;mitochondrial respiratory chain complex I;5.51343322585193e-14!GO:0016787;hydrolase activity;7.3473696900181e-14!GO:0006512;ubiquitin cycle;9.03928694631023e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.76112868578558e-13!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.66082360570082e-13!GO:0051188;cofactor biosynthetic process;9.66608869702633e-13!GO:0008135;translation factor activity, nucleic acid binding;9.66608869702633e-13!GO:0008134;transcription factor binding;1.07339024409757e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.16661933199826e-12!GO:0005789;endoplasmic reticulum membrane;1.41430853551479e-12!GO:0051603;proteolysis involved in cellular protein catabolic process;1.61561136874909e-12!GO:0009056;catabolic process;1.63547031280893e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.72102964744682e-12!GO:0044257;cellular protein catabolic process;1.86454315007492e-12!GO:0006413;translational initiation;2.16872649707893e-12!GO:0019941;modification-dependent protein catabolic process;2.68632471236411e-12!GO:0043632;modification-dependent macromolecule catabolic process;2.68632471236411e-12!GO:0006163;purine nucleotide metabolic process;3.18924643866135e-12!GO:0009150;purine ribonucleotide metabolic process;3.21308835258493e-12!GO:0005761;mitochondrial ribosome;3.7621604029501e-12!GO:0000313;organellar ribosome;3.7621604029501e-12!GO:0006511;ubiquitin-dependent protein catabolic process;4.07904075405315e-12!GO:0009259;ribonucleotide metabolic process;4.30699038527091e-12!GO:0048193;Golgi vesicle transport;6.07635035392484e-12!GO:0009152;purine ribonucleotide biosynthetic process;6.55120906248666e-12!GO:0006164;purine nucleotide biosynthetic process;7.1796806457124e-12!GO:0009055;electron carrier activity;7.1796806457124e-12!GO:0005730;nucleolus;8.0001662334813e-12!GO:0005768;endosome;1.02320822869288e-11!GO:0015078;hydrogen ion transmembrane transporter activity;1.12810802749266e-11!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.12810802749266e-11!GO:0042981;regulation of apoptosis;1.1441981671906e-11!GO:0009260;ribonucleotide biosynthetic process;1.7443749496547e-11!GO:0019829;cation-transporting ATPase activity;1.75961980713521e-11!GO:0043067;regulation of programmed cell death;1.86540686396406e-11!GO:0017076;purine nucleotide binding;2.04929413253415e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.38652085773634e-11!GO:0003743;translation initiation factor activity;2.87405512580418e-11!GO:0032553;ribonucleotide binding;2.91603142674389e-11!GO:0032555;purine ribonucleotide binding;2.91603142674389e-11!GO:0030163;protein catabolic process;3.15162811791345e-11!GO:0043412;biopolymer modification;3.16629656443715e-11!GO:0015986;ATP synthesis coupled proton transport;3.23683787381502e-11!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.23683787381502e-11!GO:0051082;unfolded protein binding;3.93220652154632e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.47865578125219e-11!GO:0006950;response to stress;8.66123844708019e-11!GO:0006913;nucleocytoplasmic transport;1.28811701994561e-10!GO:0006446;regulation of translational initiation;1.49795512041245e-10!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.77433481612727e-10!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.77433481612727e-10!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.91808116669471e-10!GO:0016887;ATPase activity;2.04455996059164e-10!GO:0009142;nucleoside triphosphate biosynthetic process;2.25535646209309e-10!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.25535646209309e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.29375556847157e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.3138978320283e-10!GO:0009144;purine nucleoside triphosphate metabolic process;2.3138978320283e-10!GO:0051169;nuclear transport;2.45249315417216e-10!GO:0009108;coenzyme biosynthetic process;2.50195028294251e-10!GO:0009199;ribonucleoside triphosphate metabolic process;2.74999369913684e-10!GO:0005774;vacuolar membrane;3.33150970488141e-10!GO:0042623;ATPase activity, coupled;3.76131220997757e-10!GO:0006464;protein modification process;3.98038184978533e-10!GO:0016604;nuclear body;4.89899448652156e-10!GO:0006754;ATP biosynthetic process;5.76632740882098e-10!GO:0006753;nucleoside phosphate metabolic process;5.76632740882098e-10!GO:0009141;nucleoside triphosphate metabolic process;6.38838626867163e-10!GO:0016469;proton-transporting two-sector ATPase complex;6.61421819145381e-10!GO:0005635;nuclear envelope;7.07778183713508e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.77520682605877e-10!GO:0000398;nuclear mRNA splicing, via spliceosome;7.77520682605877e-10!GO:0000375;RNA splicing, via transesterification reactions;7.77520682605877e-10!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;7.77520682605877e-10!GO:0043228;non-membrane-bound organelle;1.18074444368027e-09!GO:0043232;intracellular non-membrane-bound organelle;1.18074444368027e-09!GO:0046034;ATP metabolic process;1.22499187715244e-09!GO:0005770;late endosome;1.31399342742472e-09!GO:0006974;response to DNA damage stimulus;1.32237592403417e-09!GO:0016491;oxidoreductase activity;1.53796675363511e-09!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.05810604341869e-09!GO:0044437;vacuolar part;2.11698690196889e-09!GO:0005765;lysosomal membrane;2.14379287384391e-09!GO:0043069;negative regulation of programmed cell death;4.17869948431766e-09!GO:0008565;protein transporter activity;4.78786216571201e-09!GO:0043066;negative regulation of apoptosis;5.74944481798459e-09!GO:0009060;aerobic respiration;6.89580141253893e-09!GO:0051246;regulation of protein metabolic process;7.07036881171368e-09!GO:0009117;nucleotide metabolic process;1.16390046071056e-08!GO:0044440;endosomal part;1.46413709322064e-08!GO:0010008;endosome membrane;1.46413709322064e-08!GO:0008639;small protein conjugating enzyme activity;1.64234316786267e-08!GO:0030554;adenyl nucleotide binding;2.18162754157745e-08!GO:0032559;adenyl ribonucleotide binding;2.40366290724458e-08!GO:0016607;nuclear speck;2.65461211782063e-08!GO:0005524;ATP binding;2.74587957735299e-08!GO:0006916;anti-apoptosis;2.97110378650056e-08!GO:0007243;protein kinase cascade;3.21459421695728e-08!GO:0043687;post-translational protein modification;3.44247751762513e-08!GO:0006091;generation of precursor metabolites and energy;3.47075825297015e-08!GO:0005793;ER-Golgi intermediate compartment;3.55619539909891e-08!GO:0004842;ubiquitin-protein ligase activity;3.68309645060643e-08!GO:0007049;cell cycle;4.02591546472751e-08!GO:0017038;protein import;4.43341968056272e-08!GO:0003676;nucleic acid binding;4.5802998080773e-08!GO:0006461;protein complex assembly;4.61429110652832e-08!GO:0009615;response to virus;4.92656090871455e-08!GO:0044262;cellular carbohydrate metabolic process;6.01888710773526e-08!GO:0019787;small conjugating protein ligase activity;7.35903106189843e-08!GO:0045333;cellular respiration;9.97686499753626e-08!GO:0006752;group transfer coenzyme metabolic process;1.06443079288372e-07!GO:0031982;vesicle;1.18664294629382e-07!GO:0006281;DNA repair;1.4072826221155e-07!GO:0044453;nuclear membrane part;2.05533560389463e-07!GO:0042254;ribosome biogenesis and assembly;2.70989080821288e-07!GO:0006099;tricarboxylic acid cycle;2.71876188023247e-07!GO:0046356;acetyl-CoA catabolic process;2.71876188023247e-07!GO:0008654;phospholipid biosynthetic process;2.85078941666667e-07!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.02712042632846e-07!GO:0015399;primary active transmembrane transporter activity;3.02712042632846e-07!GO:0031965;nuclear membrane;3.36998571679563e-07!GO:0003712;transcription cofactor activity;4.61391721183486e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.62709959081968e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.65170726353433e-07!GO:0051187;cofactor catabolic process;5.77882184278607e-07!GO:0009719;response to endogenous stimulus;6.08800527089798e-07!GO:0031410;cytoplasmic vesicle;6.60714621897915e-07!GO:0006084;acetyl-CoA metabolic process;6.95580835512501e-07!GO:0005839;proteasome core complex (sensu Eukaryota);8.69115580040127e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.01978763815066e-06!GO:0006818;hydrogen transport;1.10273966753702e-06!GO:0044431;Golgi apparatus part;1.11505195035107e-06!GO:0031988;membrane-bound vesicle;1.27289104822391e-06!GO:0016881;acid-amino acid ligase activity;1.34034261302873e-06!GO:0022890;inorganic cation transmembrane transporter activity;1.35709104279987e-06!GO:0007040;lysosome organization and biogenesis;1.41209115460937e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;1.46010077797966e-06!GO:0048523;negative regulation of cellular process;1.47642240085928e-06!GO:0006793;phosphorus metabolic process;1.60895725512866e-06!GO:0006796;phosphate metabolic process;1.60895725512866e-06!GO:0015992;proton transport;2.08498295916467e-06!GO:0006417;regulation of translation;2.18551691523113e-06!GO:0016740;transferase activity;2.27713784903364e-06!GO:0006399;tRNA metabolic process;2.38957881762951e-06!GO:0030120;vesicle coat;2.38957881762951e-06!GO:0030662;coated vesicle membrane;2.38957881762951e-06!GO:0045259;proton-transporting ATP synthase complex;2.42450390265942e-06!GO:0009109;coenzyme catabolic process;2.69040897903021e-06!GO:0048475;coated membrane;2.85556202235254e-06!GO:0030117;membrane coat;2.85556202235254e-06!GO:0044255;cellular lipid metabolic process;3.40719126916552e-06!GO:0005643;nuclear pore;3.72696062114604e-06!GO:0031902;late endosome membrane;3.77152542293282e-06!GO:0006323;DNA packaging;4.03148146253849e-06!GO:0051170;nuclear import;4.21118140580908e-06!GO:0016023;cytoplasmic membrane-bound vesicle;4.59807146160293e-06!GO:0043492;ATPase activity, coupled to movement of substances;4.6757422699241e-06!GO:0007033;vacuole organization and biogenesis;4.80729938567994e-06!GO:0009165;nucleotide biosynthetic process;5.22140470800955e-06!GO:0016044;membrane organization and biogenesis;5.31608611965379e-06!GO:0016310;phosphorylation;5.43746109182721e-06!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;5.79023156760746e-06!GO:0005975;carbohydrate metabolic process;6.31196198091963e-06!GO:0032446;protein modification by small protein conjugation;6.76389878846095e-06!GO:0009967;positive regulation of signal transduction;7.13001186763951e-06!GO:0008026;ATP-dependent helicase activity;7.18583688739219e-06!GO:0031252;leading edge;7.35920929685887e-06!GO:0006606;protein import into nucleus;7.4945957151411e-06!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;8.18653016749184e-06!GO:0004298;threonine endopeptidase activity;8.42871741166415e-06!GO:0051726;regulation of cell cycle;8.4426898891418e-06!GO:0016567;protein ubiquitination;8.55861408191216e-06!GO:0007242;intracellular signaling cascade;8.67906859887255e-06!GO:0030532;small nuclear ribonucleoprotein complex;9.31895209461717e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.5413179881286e-06!GO:0000074;regulation of progression through cell cycle;9.66730886899493e-06!GO:0007005;mitochondrion organization and biogenesis;9.74561720211581e-06!GO:0065002;intracellular protein transport across a membrane;9.74561720211581e-06!GO:0046930;pore complex;1.02273865351416e-05!GO:0065009;regulation of a molecular function;1.13454435060007e-05!GO:0022402;cell cycle process;1.17423588757357e-05!GO:0006643;membrane lipid metabolic process;1.22670604325345e-05!GO:0048519;negative regulation of biological process;1.29590710556634e-05!GO:0008047;enzyme activator activity;1.3366351659203e-05!GO:0016070;RNA metabolic process;1.45215863081652e-05!GO:0051276;chromosome organization and biogenesis;1.50524578380123e-05!GO:0003697;single-stranded DNA binding;1.57715023117064e-05!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.7934381815814e-05!GO:0004812;aminoacyl-tRNA ligase activity;1.7934381815814e-05!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.7934381815814e-05!GO:0050657;nucleic acid transport;1.82990413197681e-05!GO:0051236;establishment of RNA localization;1.82990413197681e-05!GO:0050658;RNA transport;1.82990413197681e-05!GO:0004386;helicase activity;1.92874989745309e-05!GO:0006333;chromatin assembly or disassembly;2.00769462579524e-05!GO:0005694;chromosome;2.00769462579524e-05!GO:0005525;GTP binding;2.34510837989923e-05!GO:0006403;RNA localization;2.35859166970827e-05!GO:0043566;structure-specific DNA binding;2.64343740200559e-05!GO:0043038;amino acid activation;2.70342225388727e-05!GO:0006418;tRNA aminoacylation for protein translation;2.70342225388727e-05!GO:0043039;tRNA aminoacylation;2.70342225388727e-05!GO:0008610;lipid biosynthetic process;3.60641594677699e-05!GO:0000139;Golgi membrane;3.70191942436438e-05!GO:0006613;cotranslational protein targeting to membrane;4.10573997651839e-05!GO:0006364;rRNA processing;4.10573997651839e-05!GO:0016072;rRNA metabolic process;4.28645945556367e-05!GO:0031326;regulation of cellular biosynthetic process;4.9817525463768e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.45484303841305e-05!GO:0000245;spliceosome assembly;5.64430468643406e-05!GO:0032940;secretion by cell;5.68825804621833e-05!GO:0005741;mitochondrial outer membrane;5.72636112822036e-05!GO:0006629;lipid metabolic process;5.89765992115193e-05!GO:0019867;outer membrane;6.21361995950491e-05!GO:0065004;protein-DNA complex assembly;7.45028845841787e-05!GO:0016779;nucleotidyltransferase activity;7.64430262120506e-05!GO:0019752;carboxylic acid metabolic process;7.69852768272154e-05!GO:0044427;chromosomal part;7.70062027201494e-05!GO:0006082;organic acid metabolic process;8.0375454939739e-05!GO:0009889;regulation of biosynthetic process;8.10268343392574e-05!GO:0043065;positive regulation of apoptosis;8.5084616357788e-05!GO:0031968;organelle outer membrane;8.59314393290899e-05!GO:0000151;ubiquitin ligase complex;8.60807817571882e-05!GO:0045454;cell redox homeostasis;9.64277785102997e-05!GO:0006650;glycerophospholipid metabolic process;9.93838567789873e-05!GO:0000785;chromatin;0.000101590217693099!GO:0046474;glycerophospholipid biosynthetic process;0.000107025828735247!GO:0005798;Golgi-associated vesicle;0.000118304787960972!GO:0005762;mitochondrial large ribosomal subunit;0.000118813803458554!GO:0000315;organellar large ribosomal subunit;0.000118813803458554!GO:0006672;ceramide metabolic process;0.000120081163860663!GO:0043068;positive regulation of programmed cell death;0.00012299957970711!GO:0046519;sphingoid metabolic process;0.000131915619136867!GO:0005769;early endosome;0.000144415440984615!GO:0016197;endosome transport;0.000145359575558614!GO:0006644;phospholipid metabolic process;0.000156445920224339!GO:0046467;membrane lipid biosynthetic process;0.000158259262043327!GO:0016568;chromatin modification;0.000164909658700414!GO:0005885;Arp2/3 protein complex;0.000167812271144326!GO:0045045;secretory pathway;0.000168401346868965!GO:0045786;negative regulation of progression through cell cycle;0.000168401346868965!GO:0019899;enzyme binding;0.000172141010082018!GO:0006612;protein targeting to membrane;0.000186666654463154!GO:0007034;vacuolar transport;0.000194207460999807!GO:0001726;ruffle;0.000201278936932383!GO:0003924;GTPase activity;0.000211763270086585!GO:0048522;positive regulation of cellular process;0.000215058085036636!GO:0007264;small GTPase mediated signal transduction;0.000215574863420691!GO:0003713;transcription coactivator activity;0.000234996538752634!GO:0046483;heterocycle metabolic process;0.000238696155876985!GO:0005096;GTPase activator activity;0.000249022129488843!GO:0022415;viral reproductive process;0.000256072360165582!GO:0051028;mRNA transport;0.000257841226830887!GO:0032561;guanyl ribonucleotide binding;0.000286975255802768!GO:0019001;guanyl nucleotide binding;0.000286975255802768!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000309125657257431!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00031302987956245!GO:0003724;RNA helicase activity;0.000337979692141433!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000358469109125308!GO:0006366;transcription from RNA polymerase II promoter;0.000376830092176936!GO:0005788;endoplasmic reticulum lumen;0.000387989523046691!GO:0015980;energy derivation by oxidation of organic compounds;0.000429717150214272!GO:0006334;nucleosome assembly;0.000473617415964461!GO:0006897;endocytosis;0.000478401205550815!GO:0010324;membrane invagination;0.000478401205550815!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000480459259022518!GO:0030149;sphingolipid catabolic process;0.000503561887399883!GO:0016853;isomerase activity;0.00053386085706125!GO:0031497;chromatin assembly;0.000565093861059926!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000575538541060225!GO:0033116;ER-Golgi intermediate compartment membrane;0.000607655843342274!GO:0006260;DNA replication;0.000658366137797432!GO:0051168;nuclear export;0.000737704527048851!GO:0006917;induction of apoptosis;0.00073828565287492!GO:0030384;phosphoinositide metabolic process;0.000760251624999969!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00081386629133767!GO:0046489;phosphoinositide biosynthetic process;0.00081773305370826!GO:0019318;hexose metabolic process;0.000828686568921695!GO:0000314;organellar small ribosomal subunit;0.000830773974124819!GO:0005763;mitochondrial small ribosomal subunit;0.000830773974124819!GO:0006767;water-soluble vitamin metabolic process;0.000864182801642273!GO:0006066;alcohol metabolic process;0.000896378064642855!GO:0006733;oxidoreduction coenzyme metabolic process;0.000905441702957237!GO:0051427;hormone receptor binding;0.000908216832305098!GO:0043623;cellular protein complex assembly;0.000985871119036765!GO:0012502;induction of programmed cell death;0.00101690762995668!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00111086341029071!GO:0005996;monosaccharide metabolic process;0.00111087856714182!GO:0009607;response to biotic stimulus;0.00125198783957358!GO:0008632;apoptotic program;0.00126231100013657!GO:0019377;glycolipid catabolic process;0.00128229817198417!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0013385102007328!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0013385102007328!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0013385102007328!GO:0050790;regulation of catalytic activity;0.00135369445861018!GO:0006118;electron transport;0.00136404113032694!GO:0043021;ribonucleoprotein binding;0.00152685140872218!GO:0007006;mitochondrial membrane organization and biogenesis;0.00156226620366615!GO:0006778;porphyrin metabolic process;0.0016552266791863!GO:0033013;tetrapyrrole metabolic process;0.0016552266791863!GO:0035257;nuclear hormone receptor binding;0.0016630996282898!GO:0048518;positive regulation of biological process;0.00174244898541439!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.001897042899798!GO:0006401;RNA catabolic process;0.00197935903731334!GO:0006414;translational elongation;0.00200147497145855!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00202984994805254!GO:0007041;lysosomal transport;0.0020676254149632!GO:0004177;aminopeptidase activity;0.00212826653860257!GO:0000278;mitotic cell cycle;0.00225580549945919!GO:0030176;integral to endoplasmic reticulum membrane;0.00232085459487036!GO:0051336;regulation of hydrolase activity;0.00232327565874767!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.00239115137567694!GO:0000287;magnesium ion binding;0.00240612631450163!GO:0003729;mRNA binding;0.00244279925542397!GO:0019058;viral infectious cycle;0.0027144629355546!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0027144629355546!GO:0031072;heat shock protein binding;0.00272502901217229!GO:0019079;viral genome replication;0.00279904369756421!GO:0016564;transcription repressor activity;0.00296906341206189!GO:0003714;transcription corepressor activity;0.00305081490279624!GO:0050794;regulation of cellular process;0.00311914202534207!GO:0051789;response to protein stimulus;0.00317624441609024!GO:0006986;response to unfolded protein;0.00317624441609024!GO:0005048;signal sequence binding;0.0032092858034836!GO:0030867;rough endoplasmic reticulum membrane;0.00324743679241673!GO:0006891;intra-Golgi vesicle-mediated transport;0.0033155325053655!GO:0030695;GTPase regulator activity;0.00342818836157612!GO:0008186;RNA-dependent ATPase activity;0.0034603982599252!GO:0030984;kininogen binding;0.00350980425401201!GO:0004213;cathepsin B activity;0.00350980425401201!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00354159429348794!GO:0015002;heme-copper terminal oxidase activity;0.00354159429348794!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00354159429348794!GO:0004129;cytochrome-c oxidase activity;0.00354159429348794!GO:0015036;disulfide oxidoreductase activity;0.00367306680552875!GO:0016798;hydrolase activity, acting on glycosyl bonds;0.00378451141639806!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00378676475835205!GO:0019843;rRNA binding;0.00387105154712724!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0039707188996736!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0039707188996736!GO:0008234;cysteine-type peptidase activity;0.00399085185563854!GO:0030658;transport vesicle membrane;0.00419285513765946!GO:0042168;heme metabolic process;0.00428234143222912!GO:0046479;glycosphingolipid catabolic process;0.00435606401359822!GO:0003725;double-stranded RNA binding;0.00436824252216056!GO:0050662;coenzyme binding;0.00445079511601643!GO:0004197;cysteine-type endopeptidase activity;0.00461957677777549!GO:0019362;pyridine nucleotide metabolic process;0.00462573152060016!GO:0042158;lipoprotein biosynthetic process;0.00467854020012963!GO:0048471;perinuclear region of cytoplasm;0.00468607975367758!GO:0051920;peroxiredoxin activity;0.00474341988113007!GO:0030027;lamellipodium;0.00474341988113007!GO:0006497;protein amino acid lipidation;0.0047562836901558!GO:0043681;protein import into mitochondrion;0.00483110567124712!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00492391989916859!GO:0048487;beta-tubulin binding;0.00492694512708022!GO:0046822;regulation of nucleocytoplasmic transport;0.00515429378895986!GO:0006383;transcription from RNA polymerase III promoter;0.00529249053216639!GO:0006769;nicotinamide metabolic process;0.00531574697360781!GO:0003690;double-stranded DNA binding;0.00537924401469867!GO:0043488;regulation of mRNA stability;0.00539594305053723!GO:0043487;regulation of RNA stability;0.00539594305053723!GO:0006402;mRNA catabolic process;0.00541536479394091!GO:0004576;oligosaccharyl transferase activity;0.00541607045367997!GO:0046466;membrane lipid catabolic process;0.00571207248161357!GO:0043087;regulation of GTPase activity;0.00580688531530324!GO:0016126;sterol biosynthetic process;0.00604285009633979!GO:0005667;transcription factor complex;0.00620170241644037!GO:0008250;oligosaccharyl transferase complex;0.00642930972243574!GO:0004185;serine carboxypeptidase activity;0.00673737705523047!GO:0002376;immune system process;0.00701261062345432!GO:0051252;regulation of RNA metabolic process;0.00726521086085903!GO:0006749;glutathione metabolic process;0.0074665486248697!GO:0007265;Ras protein signal transduction;0.00746796875764998!GO:0006779;porphyrin biosynthetic process;0.00771210571367904!GO:0033014;tetrapyrrole biosynthetic process;0.00771210571367904!GO:0030118;clathrin coat;0.00787678398424465!GO:0030663;COPI coated vesicle membrane;0.0080646045806067!GO:0030126;COPI vesicle coat;0.0080646045806067!GO:0030127;COPII vesicle coat;0.0083670929410046!GO:0012507;ER to Golgi transport vesicle membrane;0.0083670929410046!GO:0006807;nitrogen compound metabolic process;0.00838118620405036!GO:0004004;ATP-dependent RNA helicase activity;0.00843452084321978!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00851688835647251!GO:0005083;small GTPase regulator activity;0.00862118132886799!GO:0006607;NLS-bearing substrate import into nucleus;0.00865387133857154!GO:0016563;transcription activator activity;0.00865969605857522!GO:0000786;nucleosome;0.00874380627190647!GO:0030133;transport vesicle;0.00968201094366941!GO:0009966;regulation of signal transduction;0.00974986390916187!GO:0030660;Golgi-associated vesicle membrane;0.00980445211219206!GO:0006979;response to oxidative stress;0.0101642557451068!GO:0016860;intramolecular oxidoreductase activity;0.0101642557451068!GO:0000096;sulfur amino acid metabolic process;0.0104425625939277!GO:0030134;ER to Golgi transport vesicle;0.0106375797443488!GO:0048500;signal recognition particle;0.0106485665122554!GO:0017166;vinculin binding;0.0109718864101006!GO:0006007;glucose catabolic process;0.0110411410734798!GO:0006740;NADPH regeneration;0.0112509476623068!GO:0006098;pentose-phosphate shunt;0.0112509476623068!GO:0042802;identical protein binding;0.0112946543246466!GO:0006509;membrane protein ectodomain proteolysis;0.0113361766914254!GO:0033619;membrane protein proteolysis;0.0113361766914254!GO:0006006;glucose metabolic process;0.0116128824529061!GO:0005905;coated pit;0.0116885009606349!GO:0048468;cell development;0.0117288346321504!GO:0004192;cathepsin D activity;0.0117780931216365!GO:0006665;sphingolipid metabolic process;0.0125095771251428!GO:0008139;nuclear localization sequence binding;0.0125095771251428!GO:0006302;double-strand break repair;0.0127056180844527!GO:0031324;negative regulation of cellular metabolic process;0.0127643364975937!GO:0030036;actin cytoskeleton organization and biogenesis;0.0128075042575054!GO:0031901;early endosome membrane;0.0128075042575054!GO:0006516;glycoprotein catabolic process;0.0129263645474996!GO:0008320;protein transmembrane transporter activity;0.0132878264109285!GO:0030137;COPI-coated vesicle;0.0133823615386736!GO:0048002;antigen processing and presentation of peptide antigen;0.0139996503478002!GO:0016125;sterol metabolic process;0.0144786519693192!GO:0006689;ganglioside catabolic process;0.0144786519693192!GO:0004553;hydrolase activity, hydrolyzing O-glycosyl compounds;0.0144959529236587!GO:0005758;mitochondrial intermembrane space;0.0146754996654872!GO:0005813;centrosome;0.014760916465872!GO:0043284;biopolymer biosynthetic process;0.0150577207366786!GO:0035035;histone acetyltransferase binding;0.0150968701885643!GO:0051287;NAD binding;0.0151680007868759!GO:0005684;U2-dependent spliceosome;0.0154528202396124!GO:0006506;GPI anchor biosynthetic process;0.0157281724163895!GO:0006914;autophagy;0.0157759306902911!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0157922711235584!GO:0045047;protein targeting to ER;0.0157922711235584!GO:0003899;DNA-directed RNA polymerase activity;0.0159518234304617!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0162324324520949!GO:0051235;maintenance of localization;0.0162675266264609!GO:0005777;peroxisome;0.0163526484628666!GO:0042579;microbody;0.0163526484628666!GO:0004229;gelatinase B activity;0.0166845178385951!GO:0006954;inflammatory response;0.0168029731580088!GO:0003711;transcription elongation regulator activity;0.0170662596509471!GO:0030145;manganese ion binding;0.0171464521995533!GO:0022406;membrane docking;0.0174174411905114!GO:0048278;vesicle docking;0.0174174411905114!GO:0006458;'de novo' protein folding;0.0179522792648394!GO:0051084;'de novo' posttranslational protein folding;0.0179522792648394!GO:0008637;apoptotic mitochondrial changes;0.0184296744811181!GO:0005099;Ras GTPase activator activity;0.0184489059006783!GO:0005791;rough endoplasmic reticulum;0.0185695482260663!GO:0030880;RNA polymerase complex;0.0186423643295196!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0187321925400811!GO:0033033;negative regulation of myeloid cell apoptosis;0.0187830269278233!GO:0001803;regulation of type III hypersensitivity;0.0187830269278233!GO:0032733;positive regulation of interleukin-10 production;0.0187830269278233!GO:0033025;regulation of mast cell apoptosis;0.0187830269278233!GO:0001805;positive regulation of type III hypersensitivity;0.0187830269278233!GO:0033023;mast cell homeostasis;0.0187830269278233!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0187830269278233!GO:0033032;regulation of myeloid cell apoptosis;0.0187830269278233!GO:0001802;type III hypersensitivity;0.0187830269278233!GO:0033028;myeloid cell apoptosis;0.0187830269278233!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0187830269278233!GO:0033026;negative regulation of mast cell apoptosis;0.0187830269278233!GO:0033024;mast cell apoptosis;0.0187830269278233!GO:0006595;polyamine metabolic process;0.018808873769049!GO:0032787;monocarboxylic acid metabolic process;0.0188849928959794!GO:0018196;peptidyl-asparagine modification;0.0188960567980741!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0188960567980741!GO:0006783;heme biosynthetic process;0.0189456142230532!GO:0005637;nuclear inner membrane;0.0189456142230532!GO:0044438;microbody part;0.0189456142230532!GO:0044439;peroxisomal part;0.0189456142230532!GO:0051087;chaperone binding;0.0196709077028045!GO:0006626;protein targeting to mitochondrion;0.0196709077028045!GO:0006790;sulfur metabolic process;0.0197949429103754!GO:0051540;metal cluster binding;0.0197949429103754!GO:0051536;iron-sulfur cluster binding;0.0197949429103754!GO:0050749;apolipoprotein E receptor binding;0.019799380678613!GO:0006839;mitochondrial transport;0.0204937012668807!GO:0006635;fatty acid beta-oxidation;0.0204943848730371!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0214481833045732!GO:0006904;vesicle docking during exocytosis;0.0216148063028201!GO:0030132;clathrin coat of coated pit;0.0221402144539694!GO:0000209;protein polyubiquitination;0.0221952733927406!GO:0006611;protein export from nucleus;0.0224679027254528!GO:0030518;steroid hormone receptor signaling pathway;0.0224679027254528!GO:0008312;7S RNA binding;0.0224793953707855!GO:0051090;regulation of transcription factor activity;0.0224857954401666!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0225069729290964!GO:0030119;AP-type membrane coat adaptor complex;0.0225335978146434!GO:0042157;lipoprotein metabolic process;0.0225930571783643!GO:0046983;protein dimerization activity;0.0226767328072232!GO:0051098;regulation of binding;0.0230201327884003!GO:0051452;cellular pH reduction;0.0234250873076405!GO:0051453;regulation of cellular pH;0.0234250873076405!GO:0045851;pH reduction;0.0234250873076405!GO:0031970;organelle envelope lumen;0.023537279108867!GO:0044275;cellular carbohydrate catabolic process;0.0235578424908256!GO:0006505;GPI anchor metabolic process;0.0236322536469106!GO:0016859;cis-trans isomerase activity;0.0237200982805149!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0240374656640451!GO:0051219;phosphoprotein binding;0.0240978598003119!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0240978598003119!GO:0010257;NADH dehydrogenase complex assembly;0.0240978598003119!GO:0033108;mitochondrial respiratory chain complex assembly;0.0240978598003119!GO:0006955;immune response;0.0240978598003119!GO:0004518;nuclease activity;0.024278296058304!GO:0000049;tRNA binding;0.0245504545993609!GO:0007050;cell cycle arrest;0.0249599569888958!GO:0006739;NADP metabolic process;0.02583587014807!GO:0032428;beta-N-acetylgalactosaminidase activity;0.0259046881950192!GO:0030290;sphingolipid activator protein activity;0.0259046881950192!GO:0015631;tubulin binding;0.0264768756984399!GO:0030041;actin filament polymerization;0.0266417065587766!GO:0009112;nucleobase metabolic process;0.0266417065587766!GO:0050811;GABA receptor binding;0.0273213709953152!GO:0006487;protein amino acid N-linked glycosylation;0.0273213709953152!GO:0009308;amine metabolic process;0.0273213709953152!GO:0031903;microbody membrane;0.0274506585641492!GO:0005778;peroxisomal membrane;0.0274506585641492!GO:0051101;regulation of DNA binding;0.0277998130779908!GO:0008033;tRNA processing;0.0280632149273511!GO:0051092;activation of NF-kappaB transcription factor;0.0280632149273511!GO:0032507;maintenance of cellular protein localization;0.0282290260141393!GO:0000118;histone deacetylase complex;0.0283488867068038!GO:0018193;peptidyl-amino acid modification;0.0285604600010072!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0287372874625224!GO:0006310;DNA recombination;0.0287372874625224!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0289415719517207!GO:0016584;nucleosome positioning;0.029222449541252!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.029222449541252!GO:0012506;vesicle membrane;0.0292775665329815!GO:0000303;response to superoxide;0.029626376369865!GO:0030503;regulation of cell redox homeostasis;0.0304304415098656!GO:0050789;regulation of biological process;0.0307700705272622!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0308207519587436!GO:0000428;DNA-directed RNA polymerase complex;0.0308207519587436!GO:0030131;clathrin adaptor complex;0.0312030188627119!GO:0022403;cell cycle phase;0.03122834264799!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.031277466981062!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.031277466981062!GO:0009126;purine nucleoside monophosphate metabolic process;0.031277466981062!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.031277466981062!GO:0051223;regulation of protein transport;0.031536274893724!GO:0016251;general RNA polymerase II transcription factor activity;0.031550356167887!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0318318133353719!GO:0032318;regulation of Ras GTPase activity;0.0319149030025945!GO:0044452;nucleolar part;0.0320017220832925!GO:0006631;fatty acid metabolic process;0.0321314915034386!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0321481374670218!GO:0030029;actin filament-based process;0.0321481374670218!GO:0015923;mannosidase activity;0.0322885035474692!GO:0000059;protein import into nucleus, docking;0.0322885035474692!GO:0006405;RNA export from nucleus;0.0323387968286376!GO:0006518;peptide metabolic process;0.0326086483467661!GO:0043022;ribosome binding;0.0334511980471176!GO:0004448;isocitrate dehydrogenase activity;0.0335914846455062!GO:0016408;C-acyltransferase activity;0.0337140526894749!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0342256786493591!GO:0035258;steroid hormone receptor binding;0.0347703537169457!GO:0051881;regulation of mitochondrial membrane potential;0.0349145616236389!GO:0045309;protein phosphorylated amino acid binding;0.0350746459016322!GO:0031625;ubiquitin protein ligase binding;0.0353021881495014!GO:0005869;dynactin complex;0.0354638619291286!GO:0051539;4 iron, 4 sulfur cluster binding;0.0355172225463118!GO:0016363;nuclear matrix;0.0355672582525832!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.035641293497612!GO:0032763;regulation of mast cell cytokine production;0.0361693323291963!GO:0032762;mast cell cytokine production;0.0361693323291963!GO:0006261;DNA-dependent DNA replication;0.0366797668355028!GO:0030508;thiol-disulfide exchange intermediate activity;0.0368830824285854!GO:0008383;manganese superoxide dismutase activity;0.0370847849481251!GO:0001315;age-dependent response to reactive oxygen species;0.0370847849481251!GO:0016272;prefoldin complex;0.0374359812776804!GO:0008629;induction of apoptosis by intracellular signals;0.0374907207303341!GO:0005784;translocon complex;0.0375980882973592!GO:0016788;hydrolase activity, acting on ester bonds;0.0381724814957869!GO:0009161;ribonucleoside monophosphate metabolic process;0.0381724814957869!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0381724814957869!GO:0009100;glycoprotein metabolic process;0.0382225524437299!GO:0045185;maintenance of protein localization;0.0382416694587717!GO:0005815;microtubule organizing center;0.0383103354065578!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0383371189175832!GO:0042987;amyloid precursor protein catabolic process;0.0384243920863009!GO:0048037;cofactor binding;0.0393656364737556!GO:0015035;protein disulfide oxidoreductase activity;0.0394758191816462!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0396020401046828!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0402077573102997!GO:0000087;M phase of mitotic cell cycle;0.0402934314944984!GO:0001887;selenium metabolic process;0.0403221550996949!GO:0046456;icosanoid biosynthetic process;0.0403400930553084!GO:0007021;tubulin folding;0.0409500645457615!GO:0019747;regulation of isoprenoid metabolic process;0.0411556357353734!GO:0042364;water-soluble vitamin biosynthetic process;0.0413883552547681!GO:0016741;transferase activity, transferring one-carbon groups;0.0414518321389465!GO:0006213;pyrimidine nucleoside metabolic process;0.0414518321389465!GO:0005484;SNAP receptor activity;0.041752988988476!GO:0007042;lysosomal lumen acidification;0.0418301666461057!GO:0030659;cytoplasmic vesicle membrane;0.0418708888624776!GO:0007162;negative regulation of cell adhesion;0.0418919497458407!GO:0006013;mannose metabolic process;0.0424562574350675!GO:0042585;germinal vesicle;0.0427920239179106!GO:0004563;beta-N-acetylhexosaminidase activity;0.0429933401369535!GO:0051085;chaperone cofactor-dependent protein folding;0.0429933401369535!GO:0009116;nucleoside metabolic process;0.0429933401369535!GO:0008180;signalosome;0.0438251317657939!GO:0008538;proteasome activator activity;0.043843626389115!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0439969035441312!GO:0030125;clathrin vesicle coat;0.0445107345097518!GO:0030665;clathrin coated vesicle membrane;0.0445107345097518!GO:0006289;nucleotide-excision repair;0.0446348586733489!GO:0006695;cholesterol biosynthetic process;0.0446683251131448!GO:0043126;regulation of 1-phosphatidylinositol 4-kinase activity;0.0449800447822017!GO:0046813;virion attachment, binding of host cell surface receptor;0.0449800447822017!GO:0043128;positive regulation of 1-phosphatidylinositol 4-kinase activity;0.0449800447822017!GO:0051651;maintenance of cellular localization;0.0450021853802562!GO:0031124;mRNA 3'-end processing;0.0453440744136059!GO:0005832;chaperonin-containing T-complex;0.0466561019322879!GO:0009892;negative regulation of metabolic process;0.0466568947803183!GO:0045947;negative regulation of translational initiation;0.0467039589373364!GO:0031529;ruffle organization and biogenesis;0.0469463768298027!GO:0008624;induction of apoptosis by extracellular signals;0.0476453196161821!GO:0007067;mitosis;0.0476585931830586!GO:0009124;nucleoside monophosphate biosynthetic process;0.0476585931830586!GO:0009123;nucleoside monophosphate metabolic process;0.0476585931830586!GO:0001784;phosphotyrosine binding;0.0477032961344717!GO:0000305;response to oxygen radical;0.0477652246159539!GO:0031301;integral to organelle membrane;0.0480409609953682!GO:0001573;ganglioside metabolic process;0.0481694454807146!GO:0003684;damaged DNA binding;0.0483035029868916!GO:0015248;sterol transporter activity;0.0489949911292658!GO:0007030;Golgi organization and biogenesis;0.0491382339348149!GO:0004674;protein serine/threonine kinase activity;0.0496242021755257!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0498249140404371 | |||
|sample_id=13323 | |||
|sample_note= | |||
|sample_sex=n/a | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|time= 00hr00min | |||
|timecourse=Macrophage_influenza_infection | |||
|top_motifs=SREBF1,2:2.86463353766;TLX2:1.59923976343;FOXD3:1.58344092272;IKZF2:1.5018309169;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.44548667887;NR6A1:1.41566190045;DMAP1_NCOR{1,2}_SMARC:1.32052115943;TFCP2:1.16994007611;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.14884470859;ARID5B:1.13224182214;SPIB:1.10211859874;ESRRA:1.09530979188;NFE2L1:1.0480935094;FOXP3:1.03377368976;PAX1,9:1.00649140776;EN1,2:1.00109723572;IRF7:0.950660605448;SPI1:0.949812147698;IRF1,2:0.922146752081;RXR{A,B,G}:0.774370966592;HMX1:0.761733994579;NKX2-2,8:0.760733150278;TFAP4:0.723828146822;ESR1:0.710701151701;PAX8:0.693980136238;EBF1:0.662512133137;NFE2L2:0.652211144943;HNF4A_NR2F1,2:0.649671505144;OCT4_SOX2{dimer}:0.628550106934;NFIL3:0.621689115659;PAX4:0.571964241684;HES1:0.568161090746;PAX2:0.549509946123;RXRA_VDR{dimer}:0.525789468364;LHX3,4:0.525642931368;CDX1,2,4:0.52051509592;POU5F1:0.508919721373;NANOG{mouse}:0.503974405893;SPZ1:0.496598084774;PPARG:0.486338300817;ETS1,2:0.454405442763;ELF1,2,4:0.428508261957;MAFB:0.415583310434;HLF:0.404763715332;RUNX1..3:0.387640546606;TGIF1:0.274850623845;TAL1_TCF{3,4,12}:0.248632488687;MYOD1:0.232516705865;bHLH_family:0.229888052031;GATA4:0.196924528854;HAND1,2:0.195010190128;STAT2,4,6:0.190919719848;AR:0.152733266569;FOX{F1,F2,J1}:0.150686369973;HBP1_HMGB_SSRP1_UBTF:0.136264178222;RORA:0.109834286087;CEBPA,B_DDIT3:0.10974546718;GLI1..3:0.107635683326;ALX1:0.0957200367322;NFKB1_REL_RELA:0.0550592979356;MYFfamily:0.0402886819857;ZBTB16:0.0344843290556;NKX6-1,2:0.017145631748;NKX3-2:0.0120117875205;VSX1,2:-0.0259504530868;NHLH1,2:-0.0393717946975;IKZF1:-0.0548229140035;KLF4:-0.0574435357456;UFEwm:-0.0659348423748;FOSL2:-0.0882657874183;GZF1:-0.10040837841;NKX2-3_NKX2-5:-0.134085603708;HMGA1,2:-0.139897843786;ALX4:-0.16280030732;BACH2:-0.162972886037;EP300:-0.1847463558;FOX{D1,D2}:-0.199978872545;NFE2:-0.200550321775;ATF5_CREB3:-0.201617070882;REST:-0.210913950968;NR5A1,2:-0.211705494558;SMAD1..7,9:-0.21623176394;STAT1,3:-0.218065408607;PRDM1:-0.220373742085;TBP:-0.266873657346;MTF1:-0.27332335842;CUX2:-0.293652187831;FOS_FOS{B,L1}_JUN{B,D}:-0.307995705648;MYB:-0.371749013835;HIF1A:-0.375651724424;RFX2..5_RFXANK_RFXAP:-0.378176798139;FOXA2:-0.39933768711;ZEB1:-0.400435430414;ZBTB6:-0.442894384598;TEF:-0.446624482221;GFI1B:-0.447832922687;HOX{A5,B5}:-0.454332970801;ATF4:-0.470637912461;PAX6:-0.493703747648;FOXQ1:-0.495143520878;GATA6:-0.49690221335;ONECUT1,2:-0.503477024171;AIRE:-0.510806301336;HOX{A6,A7,B6,B7}:-0.512810409572;PITX1..3:-0.514248799664;CRX:-0.532926464995;LMO2:-0.536985200202;PAX5:-0.552677502954;HNF1A:-0.554232581989;PDX1:-0.561141416605;FOXP1:-0.561319093512;PRRX1,2:-0.563579200539;HOXA9_MEIS1:-0.580832719523;FOXM1:-0.582947673374;FOXO1,3,4:-0.587349657169;NR1H4:-0.610553850082;SRF:-0.61939352836;T:-0.637945929547;XBP1:-0.639935321047;DBP:-0.641744398909;FOXN1:-0.642378607155;POU6F1:-0.648855896978;TOPORS:-0.657984906462;YY1:-0.667972926205;SOX5:-0.673489991333;POU1F1:-0.688502704285;HSF1,2:-0.691571972992;MEF2{A,B,C,D}:-0.696407293825;ZFP161:-0.71264834554;ELK1,4_GABP{A,B1}:-0.723143773054;ATF2:-0.742826552572;HOX{A4,D4}:-0.747350661336;NRF1:-0.757849732878;PAX3,7:-0.789957622173;SOX{8,9,10}:-0.803043744203;NFIX:-0.810179044558;CDC5L:-0.82035723066;NANOG:-0.822889929721;MYBL2:-0.840655357861;ZNF423:-0.8416395028;ZNF238:-0.852796390664;EVI1:-0.853561225866;ATF6:-0.865636930308;TFAP2{A,C}:-0.889516448047;E2F1..5:-0.895532032739;TLX1..3_NFIC{dimer}:-0.904323536471;SNAI1..3:-0.908792151137;BREu{core}:-0.913344714477;ZNF143:-0.919612740747;XCPE1{core}:-0.931202763159;HIC1:-0.939876182222;ZNF148:-0.957463938976;POU3F1..4:-0.988603119333;SOX2:-1.00005630711;MED-1{core}:-1.0012194491;SP1:-1.00317221432;ZIC1..3:-1.01648814245;AHR_ARNT_ARNT2:-1.01935021866;BPTF:-1.03425842113;GTF2I:-1.04366910597;POU2F1..3:-1.05541093152;NFATC1..3:-1.05960383149;SOX17:-1.11687417968;NR3C1:-1.11725646734;RREB1:-1.12137493048;NFY{A,B,C}:-1.13486632612;ADNP_IRX_SIX_ZHX:-1.13796238006;JUN:-1.1418911396;CREB1:-1.17766664766;TFAP2B:-1.18898790322;TP53:-1.18961230783;FOX{I1,J2}:-1.2113176339;TEAD1:-1.2175193475;NKX3-1:-1.2194476555;STAT5{A,B}:-1.25544299401;GCM1,2:-1.27300354379;GTF2A1,2:-1.28047792138;ZNF384:-1.30444714285;EGR1..3:-1.30780971394;GFI1:-1.31449386208;MTE{core}:-1.33345342669;PATZ1:-1.37282573585;MAZ:-1.39087973797;RFX1:-1.42542981097;MZF1:-1.45019960918;TFDP1:-1.50078190508;FOXL1:-1.53763503601;RBPJ:-1.66637808527;LEF1_TCF7_TCF7L1,2:-1.67775717012;NKX2-1,4:-1.87232218858;PBX1:-1.90821645117;TBX4,5:-1.9827254479 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:13323-143B2;search_select_hide=table117:FF:13323-143B2 | |||
}} | }} |
Latest revision as of 18:56, 4 June 2020
Name: | Monocyte-derived macrophages response to udorn influenza infection |
---|---|
Species: | Human (Homo sapiens) |
Library ID: | CNhs13650 |
Sample type: | time courses |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13650
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13650
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0794 |
10 | 10 | 0.0319 |
100 | 100 | 0.826 |
101 | 101 | 0.246 |
102 | 102 | 0.633 |
103 | 103 | 0.0708 |
104 | 104 | 0.764 |
105 | 105 | 0.671 |
106 | 106 | 0.017 |
107 | 107 | 0.29 |
108 | 108 | 0.635 |
109 | 109 | 0.054 |
11 | 11 | 0.0432 |
110 | 110 | 0.221 |
111 | 111 | 0.0098 |
112 | 112 | 0.029 |
113 | 113 | 0.976 |
114 | 114 | 0.00388 |
115 | 115 | 0.825 |
116 | 116 | 0.566 |
117 | 117 | 0.09 |
118 | 118 | 0.297 |
119 | 119 | 0.0819 |
12 | 12 | 0.767 |
120 | 120 | 0.163 |
121 | 121 | 0.411 |
122 | 122 | 0.958 |
123 | 123 | 0.102 |
124 | 124 | 0.396 |
125 | 125 | 0.0187 |
126 | 126 | 0.328 |
127 | 127 | 0.132 |
128 | 128 | 0.0281 |
129 | 129 | 0.377 |
13 | 13 | 0.08 |
130 | 130 | 0.402 |
131 | 131 | 0.899 |
132 | 132 | 0.548 |
133 | 133 | 0.418 |
134 | 134 | 0.609 |
135 | 135 | 0.0476 |
136 | 136 | 0.973 |
137 | 137 | 0.0759 |
138 | 138 | 0.299 |
139 | 139 | 0.0271 |
14 | 14 | 0.44 |
140 | 140 | 0.114 |
141 | 141 | 0.49 |
142 | 142 | 0.639 |
143 | 143 | 0.0986 |
144 | 144 | 0.349 |
145 | 145 | 0.29 |
146 | 146 | 0.778 |
147 | 147 | 0.513 |
148 | 148 | 0.00982 |
149 | 149 | 0.379 |
15 | 15 | 0.127 |
150 | 150 | 0.454 |
151 | 151 | 0.524 |
152 | 152 | 0.143 |
153 | 153 | 0.652 |
154 | 154 | 0.951 |
155 | 155 | 0.161 |
156 | 156 | 0.83 |
157 | 157 | 0.859 |
158 | 158 | 0.65 |
159 | 159 | 0.332 |
16 | 16 | 0.151 |
160 | 160 | 0.201 |
161 | 161 | 0.429 |
162 | 162 | 0.902 |
163 | 163 | 0.458 |
164 | 164 | 0.0973 |
165 | 165 | 0.354 |
166 | 166 | 0.698 |
167 | 167 | 0.0374 |
168 | 168 | 0.546 |
169 | 169 | 0.00343 |
17 | 17 | 0.206 |
18 | 18 | 0.134 |
19 | 19 | 0.216 |
2 | 2 | 0.841 |
20 | 20 | 0.949 |
21 | 21 | 0.351 |
22 | 22 | 0.2 |
23 | 23 | 0.23 |
24 | 24 | 0.186 |
25 | 25 | 0.467 |
26 | 26 | 0.0552 |
27 | 27 | 0.106 |
28 | 28 | 0.932 |
29 | 29 | 0.13 |
3 | 3 | 0.0422 |
30 | 30 | 0.662 |
31 | 31 | 0.515 |
32 | 32 | 0.216 |
33 | 33 | 0.307 |
34 | 34 | 0.364 |
35 | 35 | 0.256 |
36 | 36 | 0.037 |
37 | 37 | 0.0901 |
38 | 38 | 0.128 |
39 | 39 | 0.645 |
4 | 4 | 0.718 |
40 | 40 | 0.0796 |
41 | 41 | 0.139 |
42 | 42 | 0.599 |
43 | 43 | 0.11 |
44 | 44 | 0.00895 |
45 | 45 | 0.604 |
46 | 46 | 0.0796 |
47 | 47 | 0.218 |
48 | 48 | 0.192 |
49 | 49 | 0.16 |
5 | 5 | 0.374 |
50 | 50 | 0.926 |
51 | 51 | 0.337 |
52 | 52 | 0.304 |
53 | 53 | 0.479 |
54 | 54 | 0.316 |
55 | 55 | 0.245 |
56 | 56 | 0.675 |
57 | 57 | 0.401 |
58 | 58 | 0.23 |
59 | 59 | 0.095 |
6 | 6 | 0.372 |
60 | 60 | 0.0528 |
61 | 61 | 0.195 |
62 | 62 | 0.135 |
63 | 63 | 0.283 |
64 | 64 | 0.166 |
65 | 65 | 0.0872 |
66 | 66 | 0.847 |
67 | 67 | 0.087 |
68 | 68 | 0.944 |
69 | 69 | 0.46 |
7 | 7 | 0.212 |
70 | 70 | 0.0168 |
71 | 71 | 0.0477 |
72 | 72 | 0.211 |
73 | 73 | 0.0499 |
74 | 74 | 0.765 |
75 | 75 | 0.0438 |
76 | 76 | 0.352 |
77 | 77 | 0.214 |
78 | 78 | 0.0765 |
79 | 79 | 0.0169 |
8 | 8 | 0.0519 |
80 | 80 | 0.868 |
81 | 81 | 0.164 |
82 | 82 | 0.0462 |
83 | 83 | 0.81 |
84 | 84 | 0.771 |
85 | 85 | 0.0028 |
86 | 86 | 0.0824 |
87 | 87 | 0.136 |
88 | 88 | 0.506 |
89 | 89 | 0.0819 |
9 | 9 | 0.366 |
90 | 90 | 0.0127 |
91 | 91 | 0.357 |
92 | 92 | 0.0712 |
93 | 93 | 0.627 |
94 | 94 | 0.0133 |
95 | 95 | 0.0953 |
96 | 96 | 0.124 |
97 | 97 | 0.95 |
98 | 98 | 0.124 |
99 | 99 | 0.621 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13650
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011215 human Monocyte-derived macrophages 0h after udorn influenza infection sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0000255 (eukaryotic cell)
0000235 (macrophage)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000357 (0 hr sample)
0000086 (human macrophage sample)
0000647 (udorn influenza infection sample)
0011215 (human Monocyte-derived macrophages 0h after udorn influenza infection sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)