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MCL coexpression mm9:190: Difference between revisions

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{{MCL_coexpression_mm9
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cell cycle;0.033383528378983;108058,70099!GO:0022403;cell cycle phase;0.033383528378983;108058,70099!GO:0006583;melanin biosynthetic process from tyrosine;0.033383528378983;22293!GO:0005954;calcium- and calmodulin-dependent protein kinase complex;0.033383528378983;108058!GO:0060048;cardiac muscle contraction;0.033383528378983;108058!GO:0030315;T-tubule;0.0337504227630374;108058!GO:0006582;melanin metabolic process;0.0337504227630374;22293!GO:0042438;melanin biosynthetic process;0.0337504227630374;22293!GO:0006570;tyrosine metabolic process;0.0337504227630374;22293!GO:0007076;mitotic chromosome condensation;0.0337504227630374;70099!GO:0004683;calmodulin-dependent protein kinase activity;0.0337504227630374;108058!GO:0030261;chromosome condensation;0.0337504227630374;70099!GO:0000070;mitotic sister chromatid segregation;0.0337504227630374;70099!GO:0000819;sister chromatid segregation;0.0337504227630374;70099!GO:0000082;G1/S transition of mitotic cell cycle;0.0383449905330503;108058!GO:0022402;cell cycle process;0.0383449905330503;108058,70099!GO:0009072;aromatic amino acid family metabolic process;0.0383449905330503;22293!GO:0046148;pigment biosynthetic process;0.0383449905330503;22293!GO:0042383;sarcolemma;0.0383449905330503;108058!GO:0006941;striated muscle contraction;0.0383449905330503;108058!GO:0048066;pigmentation during development;0.0383449905330503;22293!GO:0042440;pigment metabolic process;0.0391198823684918;22293!GO:0046777;protein amino acid autophosphorylation;0.0394885477758235;108058!GO:0016540;protein autoprocessing;0.0394885477758235;108058!GO:0007049;cell cycle;0.0394885477758235;108058,70099!GO:0051325;interphase;0.0394885477758235;108058!GO:0051329;interphase of mitotic cell cycle;0.0394885477758235;108058!GO:0019748;secondary metabolic process;0.0394885477758235;22293!GO:0060047;heart contraction;0.0394885477758235;108058!GO:0003015;heart process;0.0394885477758235;108058!GO:0030155;regulation of cell adhesion;0.0394885477758235;!GO:0007059;chromosome segregation;0.0394885477758235;70099!GO:0005938;cell 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|gostat_on_MCL_coexpression=GO:0000278;mitotic cell cycle;0.033383528378983;108058,70099!GO:0022403;cell cycle phase;0.033383528378983;108058,70099!GO:0006583;melanin biosynthetic process from tyrosine;0.033383528378983;22293!GO:0005954;calcium- and calmodulin-dependent protein kinase complex;0.033383528378983;108058!GO:0060048;cardiac muscle contraction;0.033383528378983;108058!GO:0030315;T-tubule;0.0337504227630374;108058!GO:0006582;melanin metabolic process;0.0337504227630374;22293!GO:0042438;melanin biosynthetic process;0.0337504227630374;22293!GO:0006570;tyrosine metabolic process;0.0337504227630374;22293!GO:0007076;mitotic chromosome condensation;0.0337504227630374;70099!GO:0004683;calmodulin-dependent protein kinase activity;0.0337504227630374;108058!GO:0030261;chromosome condensation;0.0337504227630374;70099!GO:0000070;mitotic sister chromatid segregation;0.0337504227630374;70099!GO:0000819;sister chromatid segregation;0.0337504227630374;70099!GO:0000082;G1/S transition of mitotic cell cycle;0.0383449905330503;108058!GO:0022402;cell cycle process;0.0383449905330503;108058,70099!GO:0009072;aromatic amino acid family metabolic process;0.0383449905330503;22293!GO:0046148;pigment biosynthetic process;0.0383449905330503;22293!GO:0042383;sarcolemma;0.0383449905330503;108058!GO:0006941;striated muscle contraction;0.0383449905330503;108058!GO:0048066;pigmentation during development;0.0383449905330503;22293!GO:0042440;pigment metabolic process;0.0391198823684918;22293!GO:0046777;protein amino acid autophosphorylation;0.0394885477758235;108058!GO:0016540;protein autoprocessing;0.0394885477758235;108058!GO:0007049;cell cycle;0.0394885477758235;108058,70099!GO:0051325;interphase;0.0394885477758235;108058!GO:0051329;interphase of mitotic cell cycle;0.0394885477758235;108058!GO:0019748;secondary metabolic process;0.0394885477758235;22293!GO:0060047;heart contraction;0.0394885477758235;108058!GO:0003015;heart process;0.0394885477758235;108058!GO:0030155;regulation of cell adhesion;0.0394885477758235;!GO:0007059;chromosome segregation;0.0394885477758235;70099!GO:0005938;cell cortex;0.0394885477758235;!
}}

Latest revision as of 14:51, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:22026337..22026346,-p@chr10:22026337..22026346
-
Mm9::chr10:43548592..43548596,+p@chr10:43548592..43548596
+
Mm9::chr10:43717170..43717181,-p@chr10:43717170..43717181
-
Mm9::chr10:43717185..43717196,-p@chr10:43717185..43717196
-
Mm9::chr11:107330875..107330898,-p@chr11:107330875..107330898
-
Mm9::chr11:23669810..23669821,+p@chr11:23669810..23669821
+
Mm9::chr11:23670272..23670293,+p@chr11:23670272..23670293
+
Mm9::chr11:33833013..33833018,-p@chr11:33833013..33833018
-
Mm9::chr11:46200322..46200331,+p@chr11:46200322..46200331
+
Mm9::chr11:54336815..54336862,+p@chr11:54336815..54336862
+
Mm9::chr11:68911670..68911709,-p@chr11:68911670..68911709
-
Mm9::chr11:69733412..69733417,+p@chr11:69733412..69733417
+
Mm9::chr12:119615235..119615238,+p@chr12:119615235..119615238
+
Mm9::chr12:15821545..15821558,-p@chr12:15821545..15821558
-
Mm9::chr12:56547913..56547919,+p@chr12:56547913..56547919
+
Mm9::chr14:54817583..54817593,-p@chr14:54817583..54817593
-
Mm9::chr14:61665484..61665494,+p@chr14:61665484..61665494
+
Mm9::chr15:59356178..59356217,-p@chr15:59356178..59356217
-
Mm9::chr15:73006568..73006572,+p@chr15:73006568..73006572
+
Mm9::chr17:27501415..27501432,-p@chr17:27501415..27501432
-
Mm9::chr18:65481793..65481806,-p@chr18:65481793..65481806
-
Mm9::chr19:10806606..10806621,+p@chr19:10806606..10806621
+
Mm9::chr1:138476243..138476250,+p@chr1:138476243..138476250
+
Mm9::chr1:164501526..164501539,-p@chr1:164501526..164501539
-
Mm9::chr1:182286557..182286562,+p@chr1:182286557..182286562
+
Mm9::chr1:82829163..82829172,-p@chr1:82829163..82829172
-
Mm9::chr2:127141035..127141040,-p@chr2:127141035..127141040
-
Mm9::chr2:58013034..58013046,-p10@Cytip
Mm9::chr2:58013062..58013075,-p7@Cytip
Mm9::chr3:126299270..126299290,+p6@Camk2d
Mm9::chr3:68809849..68809868,+p@chr3:68809849..68809868
+
Mm9::chr3:87650806..87650827,-p@chr3:87650806..87650827
-
Mm9::chr4:133188153..133188179,+p@chr4:133188153..133188179
+
Mm9::chr4:155387843..155387856,-p@chr4:155387843..155387856
-
Mm9::chr4:155405070..155405083,+p@chr4:155405070..155405083
+
Mm9::chr4:32327445..32327449,+p@chr4:32327445..32327449
+
Mm9::chr4:32350855..32350868,+p@chr4:32350855..32350868
+
Mm9::chr5:114773355..114773367,+p@chr5:114773355..114773367
+
Mm9::chr5:22892293..22892317,-p@chr5:22892293..22892317
-
Mm9::chr6:108503087..108503091,-p@chr6:108503087..108503091
-
Mm9::chr6:122770872..122770875,-p3@ENSMUST00000112575
Mm9::chr6:125215345..125215360,-p@chr6:125215345..125215360
-
Mm9::chr6:145069654..145069666,+p@chr6:145069654..145069666
+
Mm9::chr6:48656532..48656548,+p@chr6:48656532..48656548
+
Mm9::chr7:29161745..29161757,+p@chr7:29161745..29161757
+
Mm9::chr8:14961880..14961899,+p@chr8:14961880..14961899
+
Mm9::chr8:84022563..84022566,+p@chr8:84022563..84022566
+
Mm9::chr8:84304468..84304473,-p@chr8:84304468..84304473
-
Mm9::chr9:107192291..107192309,+p@chr9:107192291..107192309
+
Mm9::chr9:107237091..107237100,+p@chr9:107237091..107237100
+
Mm9::chr9:108957297..108957310,-p@chr9:108957297..108957310
-
Mm9::chr9:44817346..44817354,-p@chr9:44817346..44817354
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0000278mitotic cell cycle0.033383528378983
GO:0022403cell cycle phase0.033383528378983
GO:0006583melanin biosynthetic process from tyrosine0.033383528378983
GO:0005954calcium- and calmodulin-dependent protein kinase complex0.033383528378983
GO:0060048cardiac muscle contraction0.033383528378983
GO:0030315T-tubule0.0337504227630374
GO:0006582melanin metabolic process0.0337504227630374
GO:0042438melanin biosynthetic process0.0337504227630374
GO:0006570tyrosine metabolic process0.0337504227630374
GO:0007076mitotic chromosome condensation0.0337504227630374
GO:0004683calmodulin-dependent protein kinase activity0.0337504227630374
GO:0030261chromosome condensation0.0337504227630374
GO:0000070mitotic sister chromatid segregation0.0337504227630374
GO:0000819sister chromatid segregation0.0337504227630374
GO:0000082G1/S transition of mitotic cell cycle0.0383449905330503
GO:0022402cell cycle process0.0383449905330503
GO:0009072aromatic amino acid family metabolic process0.0383449905330503
GO:0046148pigment biosynthetic process0.0383449905330503
GO:0042383sarcolemma0.0383449905330503
GO:0006941striated muscle contraction0.0383449905330503
GO:0048066pigmentation during development0.0383449905330503
GO:0042440pigment metabolic process0.0391198823684918
GO:0046777protein amino acid autophosphorylation0.0394885477758235
GO:0016540protein autoprocessing0.0394885477758235
GO:0007049cell cycle0.0394885477758235
GO:0051325interphase0.0394885477758235
GO:0051329interphase of mitotic cell cycle0.0394885477758235
GO:0019748secondary metabolic process0.0394885477758235
GO:0060047heart contraction0.0394885477758235
GO:0003015heart process0.0394885477758235
GO:0030155regulation of cell adhesion0.0394885477758235
GO:0007059chromosome segregation0.0394885477758235
GO:0005938cell cortex0.0394885477758235



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
mature alpha-beta T cell1.28e-539
alpha-beta T cell1.28e-539
immature T cell1.28e-539
mature T cell1.28e-539
immature alpha-beta T cell1.28e-539
lymphoid lineage restricted progenitor cell3.53e-4912
CD4-positive, alpha-beta T cell9.03e-488
lymphocyte2.53e-4513
common lymphoid progenitor2.53e-4513
T cell9.89e-4411
pro-T cell9.89e-4411
nucleate cell1.21e-3616
thymocyte4.95e-366
double negative thymocyte4.95e-366
naive T cell4.95e-366
double-positive, alpha-beta thymocyte4.95e-366
CD4-positive, alpha-beta thymocyte4.95e-366
naive thymus-derived CD4-positive, alpha-beta T cell4.95e-366
DN4 thymocyte4.95e-366
DN1 thymic pro-T cell4.95e-366
DN2 thymocyte4.95e-366
DN3 thymocyte4.95e-366
immature single positive thymocyte4.95e-366
early T lineage precursor4.95e-366
mature CD4 single-positive thymocyte4.95e-366
resting double-positive thymocyte4.95e-366
double-positive blast4.95e-366
CD69-positive double-positive thymocyte4.95e-366
CD69-positive, CD4-positive single-positive thymocyte4.95e-366
CD4-positive, CD8-intermediate double-positive thymocyte4.95e-366
CD24-positive, CD4 single-positive thymocyte4.95e-366
leukocyte1.99e-3417
nongranular leukocyte1.99e-3417
hematopoietic lineage restricted progenitor cell7.75e-2825
hematopoietic cell1.76e-2132
hematopoietic oligopotent progenitor cell1.76e-2132
hematopoietic stem cell1.76e-2132
angioblastic mesenchymal cell1.76e-2132
hematopoietic multipotent progenitor cell1.76e-2132
connective tissue cell1.50e-1446
mesenchymal cell1.50e-1446
motile cell3.41e-1254
stem cell1.99e-1097
regulatory T cell1.20e-071
CD4-positive, CD25-positive, alpha-beta regulatory T cell1.20e-071
CD8-positive, alpha-beta T cell2.11e-071
lymphocyte of B lineage4.21e-071
B cell4.21e-071
pro-B cell4.21e-071

Uber Anatomy
Ontology termp-valuen
connective tissue1.50e-1446
thymus3.37e-1223
neck3.37e-1223
respiratory system epithelium3.37e-1223
hemolymphoid system gland3.37e-1223
pharyngeal epithelium3.37e-1223
thymic region3.37e-1223
pharyngeal gland3.37e-1223
entire pharyngeal arch endoderm3.37e-1223
thymus primordium3.37e-1223
early pharyngeal endoderm3.37e-1223
pharynx1.15e-1124
gland of gut1.15e-1124
upper respiratory tract1.15e-1124
chordate pharynx1.15e-1124
pharyngeal arch system1.15e-1124
pharyngeal region of foregut1.15e-1124
segment of respiratory tract2.65e-1027
hemopoietic organ1.50e-0929
immune organ1.50e-0929
mixed endoderm/mesoderm-derived structure8.39e-0835
organ segment8.39e-0835
hematopoietic system1.18e-0745
blood island1.18e-0745
craniocervical region1.44e-0736
hemolymphoid system4.02e-0748
immune system4.02e-0748


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.1912e-06
MA0004.11.08764
MA0006.10.0588308
MA0007.10.691605
MA0009.10.614771
MA0014.10.000125913
MA0017.10.749801
MA0019.10.110663
MA0024.10.187051
MA0025.10.383522
MA0027.11.70825
MA0028.10.0210427
MA0029.10.173922
MA0030.10.177847
MA0031.10.157022
MA0038.10.491425
MA0040.10.222824
MA0041.10.144079
MA0042.10.0465591
MA0043.10.280639
MA0046.10.238407
MA0048.10.165895
MA0050.10.302298
MA0051.10.236374
MA0052.10.228144
MA0055.10.0137417
MA0056.10
MA0057.10.723378
MA0058.10.976702
MA0059.11.03921
MA0060.10.0502058
MA0061.14.86482
MA0063.10
MA0066.10.0594129
MA0067.10.473816
MA0068.11.66704
MA0069.10.228369
MA0070.10.632033
MA0071.11.26202
MA0072.10.216436
MA0073.10.013129
MA0074.10.17954
MA0076.10.0323376
MA0077.10.585966
MA0078.10.57557
MA0081.10.546493
MA0083.10.280072
MA0084.10.763469
MA0087.10.249896
MA0088.10.0479638
MA0089.10
MA0090.11.29947
MA0091.10.490328
MA0092.10.195477
MA0093.11.66182
MA0095.10
MA0098.10
MA0100.10.0440101
MA0101.13.32367
MA0103.10.548486
MA0105.12.44426
MA0106.10.282193
MA0107.15.275
MA0108.21.26369
MA0109.10
MA0111.10.214158
MA0113.10.910634
MA0114.10.264488
MA0115.11.41067
MA0116.10.419744
MA0117.10.720237
MA0119.10.770704
MA0122.10.273795
MA0124.10.429916
MA0125.10.3708
MA0130.10
MA0131.10.108468
MA0132.10
MA0133.10
MA0135.10.307058
MA0136.10.768486
MA0139.10.0296623
MA0140.11.05291
MA0141.10.224811
MA0142.10.148854
MA0143.10.268535
MA0144.11.12235
MA0145.10.236787
MA0146.10.00104964
MA0147.10.178678
MA0148.10.110009
MA0149.10.0115146
MA0062.20.0714837
MA0035.20.693023
MA0039.20.11689
MA0138.20.104681
MA0002.21.18301
MA0137.20.881105
MA0104.20.088372
MA0047.20.225984
MA0112.20.161088
MA0065.20.740901
MA0150.10.221082
MA0151.10
MA0152.10.490141
MA0153.10.319381
MA0154.10.814167
MA0155.10.144827
MA0156.10.83587
MA0157.10.131489
MA0158.10
MA0159.10.101355
MA0160.10.505315
MA0161.10
MA0162.10.0321203
MA0163.10.00339676
MA0164.10.0540521
MA0080.20.775537
MA0018.21.21373
MA0099.20.333371
MA0079.20.000652988
MA0102.20.812014
MA0258.10.542211
MA0259.10.433914
MA0442.10