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MCL coexpression mm9:1580: Difference between revisions

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{{MCL_coexpression_mm9
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sulfate proteoglycan biosynthetic process;0.00320495261052977;72136!GO:0030205;dermatan sulfate metabolic process;0.00320495261052977;72136!GO:0030208;dermatan sulfate biosynthetic process;0.00320495261052977;72136!GO:0050655;dermatan sulfate proteoglycan metabolic process;0.00320495261052977;72136!GO:0001537;N-acetylgalactosamine 4-O-sulfotransferase activity;0.00549360244756628;72136!GO:0030206;chondroitin sulfate biosynthetic process;0.00549360244756628;72136!GO:0030204;chondroitin sulfate metabolic process;0.00549360244756628;72136!GO:0050650;chondroitin sulfate proteoglycan biosynthetic process;0.00712055615693433;72136!GO:0050654;chondroitin sulfate proteoglycan metabolic process;0.00712055615693433;72136!GO:0006024;glycosaminoglycan biosynthetic process;0.00815537962692766;72136!GO:0006023;aminoglycan biosynthetic process;0.00815537962692766;72136!GO:0008417;fucosyltransferase activity;0.0117450554949872;73068!GO:0030166;proteoglycan biosynthetic 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|gostat_on_MCL_coexpression=GO:0050651;dermatan sulfate proteoglycan biosynthetic process;0.00320495261052977;72136!GO:0030205;dermatan sulfate metabolic process;0.00320495261052977;72136!GO:0030208;dermatan sulfate biosynthetic process;0.00320495261052977;72136!GO:0050655;dermatan sulfate proteoglycan metabolic process;0.00320495261052977;72136!GO:0001537;N-acetylgalactosamine 4-O-sulfotransferase activity;0.00549360244756628;72136!GO:0030206;chondroitin sulfate biosynthetic process;0.00549360244756628;72136!GO:0030204;chondroitin sulfate metabolic process;0.00549360244756628;72136!GO:0050650;chondroitin sulfate proteoglycan biosynthetic process;0.00712055615693433;72136!GO:0050654;chondroitin sulfate proteoglycan metabolic process;0.00712055615693433;72136!GO:0006024;glycosaminoglycan biosynthetic process;0.00815537962692766;72136!GO:0006023;aminoglycan biosynthetic process;0.00815537962692766;72136!GO:0008417;fucosyltransferase activity;0.0117450554949872;73068!GO:0030166;proteoglycan biosynthetic process;0.0121668129786169;72136!GO:0005794;Golgi apparatus;0.0121668129786169;72136,73068!GO:0042632;cholesterol homeostasis;0.0121668129786169;70310!GO:0055088;lipid homeostasis;0.0121668129786169;70310!GO:0055092;sterol homeostasis;0.0121668129786169;70310!GO:0006029;proteoglycan metabolic process;0.0121668129786169;72136!GO:0006022;aminoglycan metabolic process;0.0121668129786169;72136!GO:0030203;glycosaminoglycan metabolic process;0.0121668129786169;72136!GO:0009059;macromolecule biosynthetic process;0.013359548991871;72136,73068!GO:0042593;glucose homeostasis;0.0154668522003998;70310!GO:0033500;carbohydrate homeostasis;0.0154668522003998;70310!GO:0044272;sulfur compound biosynthetic process;0.0154668522003998;72136!GO:0008146;sulfotransferase activity;0.022509751156262;72136!GO:0016782;transferase activity, transferring sulfur-containing groups;0.0250777257891718;72136!GO:0006790;sulfur metabolic process;0.0283964755883061;72136!GO:0009058;biosynthetic process;0.0311107170377084;72136,73068!GO:0006486;protein amino acid glycosylation;0.0325304211573446;73068!GO:0043413;biopolymer glycosylation;0.0325304211573446;73068!GO:0016051;carbohydrate biosynthetic process;0.0325304211573446;72136!GO:0009101;glycoprotein biosynthetic process;0.0334992009021274;73068!GO:0009100;glycoprotein metabolic process;0.0378689794229424;73068!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002048!3.82e-07!14;UBERON:0000117!3.82e-07!14;UBERON:0000171!3.82e-07!14;UBERON:0000170!3.82e-07!14;UBERON:0005597!3.82e-07!14;UBERON:0000118!3.82e-07!14
|tfbs_overrepresentation_for_novel_motifs=0.557864,2.7192,0.529553,0.603273,0.406364,0.618805,0.715644,0.300268,0.310789,0.370407,0.668936,0.702872,0.300533,0.728641,0.424775,0,0.930881,0.397593,1.41491,1.0421,0.489529,0.44579,0.727684,1.04384,1.32977,0.757752,1.38127,0.641282,0.456327,1.87618,0.626183,1.03545,0.395107,0.704734,0.425309,0.20704,0.384813,0.699032,0.360612,0.328675,0.401916,0.631725,0.134724,0.426986,0.0637209,0.591277,0.847828,0.658142,0.115788,0.459555,0.912738,1.84811,0.220111,1.18062,1.19842,0.73621,0.469329,1.64777,0.26467,0.734051,1.01481,0.796017,0.323911,0.901018,0.747985,0.943088,1.33705,1.68977,1.00999,1.54147,0.509047,0.30684,0.152094,1.23259,0.257421,1.27178,0.253065,0.835925,0.997094,0.494135,0.308173,0.948899,0.794502,0.293164,1.1148,0.574099,0.297068,0.227755,0.852952,1.85284,1.40768,1.11989,1.04863,0.412897,0.356133,0.3366,0.297538,1.05152,0.848095,0.20438,0.384901,1.03517,1.16282,0.913356,0.91226,0.631253,0.97421,0.653843,0.499439,1.23125,0.550229,1.16464,0.495367,0.674448,1.41481,0.399936,0.0998646,0.607321,0.932233,0.380707,1.23809,0.879184,1.7936,0.834976,5.1756,1.00091,0.724289,1.04166,1.33551,0.416189,1.14546,0.595426,1.3055,0.750642,1.43666,0.143464,0.566955,0.633235,1.3869,2.2222,1.82084,1.34183,0.772375,1.04623,0.905521,0.632211,3.28302,2.18247,0.569503,0.408309,0.651755,0.133815,1.18223,0.343194,0.749664,1.26545,0.787153,0.438007,0.555203,0.566652,1.39653,1.11392,1.00137,0.547782,0.90208,0.741834,0.383572,0.701187,1.14345
}}

Latest revision as of 17:09, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:69660112..69660161,+p1@Plscr3
Mm9::chr14:21514178..21514207,+p1@Fut11
Mm9::chr2:118752232..118752290,+p1@Chst14
Mm9::chr2:118752291..118752311,+p2@Chst14
Mm9::chr2:118752312..118752344,+p3@Chst14


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050651dermatan sulfate proteoglycan biosynthetic process0.00320495261052977
GO:0030205dermatan sulfate metabolic process0.00320495261052977
GO:0030208dermatan sulfate biosynthetic process0.00320495261052977
GO:0050655dermatan sulfate proteoglycan metabolic process0.00320495261052977
GO:0001537N-acetylgalactosamine 4-O-sulfotransferase activity0.00549360244756628
GO:0030206chondroitin sulfate biosynthetic process0.00549360244756628
GO:0030204chondroitin sulfate metabolic process0.00549360244756628
GO:0050650chondroitin sulfate proteoglycan biosynthetic process0.00712055615693433
GO:0050654chondroitin sulfate proteoglycan metabolic process0.00712055615693433
GO:0006024glycosaminoglycan biosynthetic process0.00815537962692766
GO:0006023aminoglycan biosynthetic process0.00815537962692766
GO:0008417fucosyltransferase activity0.0117450554949872
GO:0030166proteoglycan biosynthetic process0.0121668129786169
GO:0005794Golgi apparatus0.0121668129786169
GO:0042632cholesterol homeostasis0.0121668129786169
GO:0055088lipid homeostasis0.0121668129786169
GO:0055092sterol homeostasis0.0121668129786169
GO:0006029proteoglycan metabolic process0.0121668129786169
GO:0006022aminoglycan metabolic process0.0121668129786169
GO:0030203glycosaminoglycan metabolic process0.0121668129786169
GO:0009059macromolecule biosynthetic process0.013359548991871
GO:0042593glucose homeostasis0.0154668522003998
GO:0033500carbohydrate homeostasis0.0154668522003998
GO:0044272sulfur compound biosynthetic process0.0154668522003998
GO:0008146sulfotransferase activity0.022509751156262
GO:0016782transferase activity, transferring sulfur-containing groups0.0250777257891718
GO:0006790sulfur metabolic process0.0283964755883061
GO:0009058biosynthetic process0.0311107170377084
GO:0006486protein amino acid glycosylation0.0325304211573446
GO:0043413biopolymer glycosylation0.0325304211573446
GO:0016051carbohydrate biosynthetic process0.0325304211573446
GO:0009101glycoprotein biosynthetic process0.0334992009021274
GO:0009100glycoprotein metabolic process0.0378689794229424



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lung3.82e-0714
respiratory tube3.82e-0714
respiration organ3.82e-0714
pair of lungs3.82e-0714
lung primordium3.82e-0714
lung bud3.82e-0714


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.36559
MA0004.11.46913
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.13.30772
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.11.10192
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.602741
MA0056.10
MA0057.10.562607
MA0058.12.16203
MA0059.11.27866
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.11.08757
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.0481612
MA0074.10.708108
MA0076.11.1853
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.13.51516
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.11.12162
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.949408
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.476962
MA0146.10.822925
MA0147.11.75115
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.26.99635
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.21.52809
MA0047.20.75686
MA0112.24.45936
MA0065.20.477991
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.11.11105
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.11.78974
MA0160.10.624415
MA0161.10
MA0162.10.898893
MA0163.10.855539
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.23.01303
MA0102.21.79669
MA0258.10.91616
MA0259.10.366802
MA0442.10