Novel motif:123

name:	motif123_TTGATGCAGTGA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	7.512939e-25
GO:0007154	cell communication	2.599453e-20
GO:0050794	regulation of cellular process	3.199172e-20
GO:0050789	regulation of biological process	2.347511e-19
GO:0023052	signaling	2.489128e-19
GO:0051716	cellular response to stimulus	2.792350e-19
GO:0007165	signal transduction	7.738911e-19
GO:0007166	cell surface receptor linked signaling pathway	1.263087e-17
GO:0065007	biological regulation	2.999198e-17
GO:0044281	small molecule metabolic process	1.226405e-15
GO:0002376	immune system process	1.574529e-13
GO:0006950	response to stress	2.069427e-13
GO:0030277	maintenance of gastrointestinal epithelium	5.777466e-13
GO:0007586	digestion	1.325602e-12
GO:0043316	cytotoxic T cell degranulation	9.813763e-12
GO:0006520	cellular amino acid metabolic process	4.007578e-11
GO:0046209	nitric oxide metabolic process	4.015559e-11
GO:0019752	carboxylic acid metabolic process	1.386506e-10
GO:0006952	defense response	2.036396e-10
GO:0042180	cellular ketone metabolic process	2.345853e-10
GO:0006082	organic acid metabolic process	2.783671e-10
GO:0008152	metabolic process	2.818179e-10
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.182115e-10
GO:0010669	epithelial structure maintenance	4.508576e-10
GO:0048519	negative regulation of biological process	6.789334e-10
GO:0006306	DNA methylation	7.067661e-10
GO:0010522	regulation of calcium ion transport into cytosol	1.219779e-9
GO:0044085	cellular component biogenesis	1.884912e-9
GO:0009987	cellular process	2.013218e-9
GO:0045321	leukocyte activation	2.100655e-9
GO:0019538	protein metabolic process	3.771436e-9
GO:0035556	intracellular signal transduction	4.192998e-9
GO:0045087	innate immune response	5.783201e-9
GO:0032501	multicellular organismal process	9.607939e-9
GO:0051047	positive regulation of secretion	9.720681e-9
GO:0022607	cellular component assembly	1.037025e-8
GO:0006955	immune response	1.286316e-8
GO:0043412	macromolecule modification	1.321207e-8
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.340390e-8
GO:0009056	catabolic process	1.348082e-8
GO:0033036	macromolecule localization	1.375355e-8
GO:0042110	T cell activation	1.660384e-8
GO:0019226	transmission of nerve impulse	1.733496e-8
GO:0008104	protein localization	1.968828e-8
GO:0045919	positive regulation of cytolysis	1.986840e-8
GO:0019953	sexual reproduction	2.121585e-8
GO:0043046	DNA methylation involved in gamete generation	2.248177e-8
GO:0044106	cellular amine metabolic process	2.570433e-8
GO:0000398	nuclear mRNA splicing, via spliceosome	2.922514e-8
GO:0072521	purine-containing compound metabolic process	3.012271e-8
GO:0044237	cellular metabolic process	3.273703e-8
GO:0044248	cellular catabolic process	3.355524e-8
GO:0006796	phosphate-containing compound metabolic process	3.719502e-8
GO:0009308	amine metabolic process	3.804462e-8
GO:0006304	DNA modification	4.533545e-8
GO:0043132	NAD transport	4.872513e-8
GO:0044238	primary metabolic process	5.661914e-8
GO:0006346	methylation-dependent chromatin silencing	6.164262e-8
GO:0023057	negative regulation of signaling	6.258931e-8
GO:0016310	phosphorylation	6.407917e-8
GO:0055086	nucleobase-containing small molecule metabolic process	6.728207e-8
GO:0010648	negative regulation of cell communication	6.851365e-8
GO:0051050	positive regulation of transport	7.412209e-8
GO:0071844	cellular component assembly at cellular level	7.439471e-8
GO:0046649	lymphocyte activation	7.640913e-8
GO:0046483	heterocycle metabolic process	9.670581e-8
GO:0000375	RNA splicing, via transesterification reactions	1.005577e-7
GO:0051924	regulation of calcium ion transport	1.029112e-7
GO:0071285	cellular response to lithium ion	1.253512e-7
GO:0010042	response to manganese ion	1.301531e-7
GO:0071840	cellular component organization or biogenesis	1.304681e-7
GO:0043170	macromolecule metabolic process	1.322480e-7
GO:0050999	regulation of nitric-oxide synthase activity	1.330478e-7
GO:0009143	nucleoside triphosphate catabolic process	1.411505e-7
GO:0046128	purine ribonucleoside metabolic process	1.425592e-7
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.436022e-7
GO:0042391	regulation of membrane potential	1.563240e-7
GO:0043409	negative regulation of MAPKKK cascade	1.689824e-7
GO:0001508	regulation of action potential	1.731125e-7
GO:0051049	regulation of transport	1.856902e-7
GO:0016098	monoterpenoid metabolic process	2.006653e-7
GO:0009119	ribonucleoside metabolic process	2.084397e-7
GO:0061024	membrane organization	2.088743e-7
GO:0007276	gamete generation	2.104075e-7
GO:0009207	purine ribonucleoside triphosphate catabolic process	2.109673e-7
GO:0009146	purine nucleoside triphosphate catabolic process	2.167864e-7
GO:0048523	negative regulation of cellular process	2.230853e-7
GO:0002709	regulation of T cell mediated immunity	2.338797e-7
GO:0071681	cellular response to indole-3-methanol	2.742626e-7
GO:0022600	digestive system process	2.753673e-7
GO:0044271	cellular nitrogen compound biosynthetic process	2.843998e-7
GO:0010243	response to organic nitrogen	3.022878e-7
GO:0043414	macromolecule methylation	3.048635e-7
GO:0016044	cellular membrane organization	3.179835e-7
GO:0016043	cellular component organization	3.268155e-7
GO:0065003	macromolecular complex assembly	3.732674e-7
GO:0009154	purine ribonucleotide catabolic process	3.845826e-7
GO:0044254	multicellular organismal protein catabolic process	3.983758e-7
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	4.093690e-7
GO:0034097	response to cytokine stimulus	4.096143e-7
GO:0010741	negative regulation of intracellular protein kinase cascade	4.146669e-7
GO:0006468	protein phosphorylation	4.243568e-7
GO:0009261	ribonucleotide catabolic process	5.012274e-7
GO:0071230	cellular response to amino acid stimulus	5.167672e-7
GO:0042278	purine nucleoside metabolic process	5.243519e-7
GO:0050880	regulation of blood vessel size	5.275744e-7
GO:0016192	vesicle-mediated transport	5.555304e-7
GO:0042851	L-alanine metabolic process	5.813073e-7
GO:0014052	regulation of gamma-aminobutyric acid secretion	5.819553e-7
GO:0051179	localization	5.830374e-7
GO:0051341	regulation of oxidoreductase activity	5.870783e-7
GO:0006730	one-carbon metabolic process	6.333536e-7
GO:0042311	vasodilation	6.376117e-7
GO:0046456	icosanoid biosynthetic process	6.504934e-7
GO:0035150	regulation of tube size	6.871791e-7
GO:0001775	cell activation	7.162680e-7
GO:0032006	regulation of TOR signaling cascade	7.580511e-7
GO:0048585	negative regulation of response to stimulus	8.004802e-7
GO:0044267	cellular protein metabolic process	8.221767e-7
GO:0006464	protein modification process	8.288717e-7
GO:0050717	positive regulation of interleukin-1 alpha secretion	9.311401e-7
GO:0033561	regulation of water loss via skin	9.311401e-7
GO:0002706	regulation of lymphocyte mediated immunity	9.931559e-7
GO:0003018	vascular process in circulatory system	1.034083e-6
GO:0048583	regulation of response to stimulus	1.094538e-6
GO:0044268	multicellular organismal protein metabolic process	1.165050e-6
GO:0006690	icosanoid metabolic process	1.217524e-6
GO:0045428	regulation of nitric oxide biosynthetic process	1.282672e-6
GO:0006897	endocytosis	1.298154e-6
GO:0043269	regulation of ion transport	1.426292e-6
GO:0009117	nucleotide metabolic process	1.444730e-6
GO:0031508	centromeric heterochromatin formation	1.465628e-6
GO:0007519	skeletal muscle tissue development	1.571392e-6
GO:0046039	GTP metabolic process	1.581089e-6
GO:0019228	regulation of action potential in neuron	1.586364e-6
GO:0051222	positive regulation of protein transport	1.598588e-6
GO:0001845	phagolysosome assembly	1.629395e-6
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	1.713153e-6
GO:0006636	unsaturated fatty acid biosynthetic process	1.766984e-6
GO:0042738	exogenous drug catabolic process	1.799330e-6
GO:0035914	skeletal muscle cell differentiation	1.916031e-6
GO:0031069	hair follicle morphogenesis	1.916031e-6
GO:0033059	cellular pigmentation	1.916031e-6
GO:0034655	nucleobase-containing compound catabolic process	1.922872e-6
GO:0042737	drug catabolic process	2.040635e-6
GO:0032008	positive regulation of TOR signaling cascade	2.061921e-6
GO:2000008	regulation of protein localization at cell surface	2.316439e-6
GO:0072523	purine-containing compound catabolic process	2.367603e-6
GO:0015031	protein transport	2.373038e-6
GO:0065009	regulation of molecular function	2.426467e-6
GO:0007155	cell adhesion	2.624893e-6
GO:0009309	amine biosynthetic process	2.635197e-6
GO:0007292	female gamete generation	2.676302e-6
GO:0006195	purine nucleotide catabolic process	2.693405e-6
GO:0033559	unsaturated fatty acid metabolic process	2.774100e-6
GO:0045184	establishment of protein localization	2.776300e-6
GO:0051955	regulation of amino acid transport	3.023358e-6
GO:0030101	natural killer cell activation	3.055786e-6
GO:0044270	cellular nitrogen compound catabolic process	3.087591e-6
GO:0014902	myotube differentiation	3.087936e-6
GO:0051875	pigment granule localization	3.199836e-6
GO:0008652	cellular amino acid biosynthetic process	3.245938e-6
GO:0006559	L-phenylalanine catabolic process	3.272999e-6
GO:0032465	regulation of cytokinesis	3.329438e-6
GO:0009144	purine nucleoside triphosphate metabolic process	3.698936e-6
GO:0010799	regulation of peptidyl-threonine phosphorylation	3.870453e-6
GO:0060538	skeletal muscle organ development	4.019434e-6
GO:0032880	regulation of protein localization	4.029944e-6
GO:0051262	protein tetramerization	4.170880e-6
GO:0009141	nucleoside triphosphate metabolic process	4.257308e-6
GO:0034332	adherens junction organization	4.294885e-6
GO:0032259	methylation	4.331039e-6
GO:0034613	cellular protein localization	4.393113e-6
GO:0006184	GTP catabolic process	4.424417e-6
GO:0051704	multi-organism process	4.557353e-6
GO:0032879	regulation of localization	4.640072e-6
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	4.642729e-6
GO:0046324	regulation of glucose import	4.699181e-6
GO:2000021	regulation of ion homeostasis	4.866724e-6
GO:0032943	mononuclear cell proliferation	5.053271e-6
GO:0044070	regulation of anion transport	5.323646e-6
GO:0070727	cellular macromolecule localization	5.351252e-6
GO:0009166	nucleotide catabolic process	5.377654e-6
GO:0009205	purine ribonucleoside triphosphate metabolic process	5.590008e-6
GO:0009968	negative regulation of signal transduction	5.827262e-6
GO:0072593	reactive oxygen species metabolic process	6.433738e-6
GO:0009199	ribonucleoside triphosphate metabolic process	6.776480e-6
GO:0002726	positive regulation of T cell cytokine production	6.888237e-6
GO:0051234	establishment of localization	6.898510e-6
GO:0006572	tyrosine catabolic process	6.955567e-6
GO:0032844	regulation of homeostatic process	7.015958e-6
GO:0071418	cellular response to amine stimulus	7.327731e-6
GO:0042633	hair cycle	7.380331e-6
GO:0035587	purinergic receptor signaling pathway	8.180444e-6
GO:0046700	heterocycle catabolic process	8.301462e-6
GO:0032060	bleb assembly	8.548625e-6
GO:0006810	transport	8.597059e-6
GO:0032730	positive regulation of interleukin-1 alpha production	8.716174e-6
GO:0043029	T cell homeostasis	8.854369e-6
GO:0006163	purine nucleotide metabolic process	9.508810e-6
GO:0006103	2-oxoglutarate metabolic process	9.602205e-6
GO:0002703	regulation of leukocyte mediated immunity	1.014966e-5
GO:0065008	regulation of biological quality	1.015623e-5
GO:0043200	response to amino acid stimulus	1.036284e-5
GO:0071417	cellular response to organic nitrogen	1.098038e-5
GO:0010453	regulation of cell fate commitment	1.155841e-5
GO:0019229	regulation of vasoconstriction	1.175303e-5
GO:0048609	multicellular organismal reproductive process	1.208208e-5
GO:0071826	ribonucleoprotein complex subunit organization	1.262330e-5
GO:0002711	positive regulation of T cell mediated immunity	1.265210e-5
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	1.293912e-5
GO:0008380	RNA splicing	1.297608e-5
GO:0045768	positive regulation of anti-apoptosis	1.405244e-5
GO:0032768	regulation of monooxygenase activity	1.431272e-5
GO:0014049	positive regulation of glutamate secretion	1.483066e-5
GO:0001942	hair follicle development	1.532601e-5
GO:0032400	melanosome localization	1.556436e-5
GO:0045767	regulation of anti-apoptosis	1.596472e-5
GO:0016337	cell-cell adhesion	1.612527e-5
GO:0003008	system process	1.626480e-5
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	1.656785e-5
GO:0022618	ribonucleoprotein complex assembly	1.662027e-5
GO:0034622	cellular macromolecular complex assembly	1.670245e-5
GO:0007167	enzyme linked receptor protein signaling pathway	1.708088e-5
GO:0001101	response to acid	1.709084e-5
GO:0007268	synaptic transmission	1.722530e-5
GO:0006649	phospholipid transfer to membrane	1.735055e-5
GO:0010828	positive regulation of glucose transport	1.793188e-5
GO:0001516	prostaglandin biosynthetic process	1.818842e-5
GO:0010959	regulation of metal ion transport	1.835666e-5
GO:0045576	mast cell activation	1.852455e-5
GO:0006552	leucine catabolic process	1.854753e-5
GO:0023051	regulation of signaling	1.900966e-5
GO:0022406	membrane docking	1.916403e-5
GO:0060662	salivary gland cavitation	1.936859e-5
GO:0014075	response to amine stimulus	1.981006e-5
GO:0070271	protein complex biogenesis	1.999419e-5
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	2.101325e-5
GO:0043497	regulation of protein heterodimerization activity	2.143867e-5
GO:0048172	regulation of short-term neuronal synaptic plasticity	2.161422e-5
GO:0043933	macromolecular complex subunit organization	2.209446e-5
GO:0006461	protein complex assembly	2.261222e-5
GO:0070201	regulation of establishment of protein localization	2.267875e-5
GO:0051223	regulation of protein transport	2.305088e-5
GO:0007267	cell-cell signaling	2.319236e-5
GO:0046394	carboxylic acid biosynthetic process	2.471371e-5
GO:0010518	positive regulation of phospholipase activity	2.489571e-5
GO:0007416	synapse assembly	2.531772e-5
GO:0042264	peptidyl-aspartic acid hydroxylation	2.659674e-5
GO:0060341	regulation of cellular localization	2.659848e-5
GO:0090232	positive regulation of spindle checkpoint	2.773449e-5
GO:0046499	S-adenosylmethioninamine metabolic process	2.843876e-5
GO:0051279	regulation of release of sequestered calcium ion into cytosol	2.865394e-5
GO:0032228	regulation of synaptic transmission, GABAergic	2.880125e-5
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	3.228369e-5
GO:0051970	negative regulation of transmission of nerve impulse	3.310511e-5
GO:0043045	DNA methylation involved in embryo development	3.361127e-5
GO:0006417	regulation of translation	3.469434e-5
GO:0022613	ribonucleoprotein complex biogenesis	3.541934e-5
GO:0002246	wound healing involved in inflammatory response	3.582150e-5
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3.594689e-5
GO:0009150	purine ribonucleotide metabolic process	3.775707e-5
GO:0015747	urate transport	3.828065e-5
GO:0006807	nitrogen compound metabolic process	3.829934e-5
GO:0051152	positive regulation of smooth muscle cell differentiation	3.969236e-5
GO:0018298	protein-chromophore linkage	3.969236e-5
GO:0043320	natural killer cell degranulation	4.013297e-5
GO:0071345	cellular response to cytokine stimulus	4.052630e-5
GO:0050765	negative regulation of phagocytosis	4.101176e-5
GO:0090116	C-5 methylation of cytosine	4.174245e-5
GO:0002697	regulation of immune effector process	4.187400e-5
GO:0022414	reproductive process	4.240891e-5
GO:0009259	ribonucleotide metabolic process	4.252237e-5
GO:0007173	epidermal growth factor receptor signaling pathway	4.324684e-5
GO:0033962	cytoplasmic mRNA processing body assembly	4.391859e-5
GO:0051414	response to cortisol stimulus	4.485195e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	4.544033e-5
GO:0051289	protein homotetramerization	4.649771e-5
GO:0002819	regulation of adaptive immune response	4.774802e-5
GO:0071841	cellular component organization or biogenesis at cellular level	4.878646e-5
GO:0010517	regulation of phospholipase activity	4.987107e-5
GO:0010966	regulation of phosphate transport	5.125392e-5
GO:0034587	piRNA metabolic process	5.200808e-5
GO:0002724	regulation of T cell cytokine production	5.216045e-5
GO:0002682	regulation of immune system process	5.355243e-5
GO:0014057	positive regulation of acetylcholine secretion	5.371542e-5
GO:0010646	regulation of cell communication	5.403064e-5
GO:0071843	cellular component biogenesis at cellular level	5.812563e-5
GO:0002443	leukocyte mediated immunity	5.881444e-5
GO:0032873	negative regulation of stress-activated MAPK cascade	5.959755e-5
GO:0050790	regulation of catalytic activity	6.051817e-5
GO:0042592	homeostatic process	6.094278e-5
GO:0000003	reproduction	6.157375e-5
GO:0019221	cytokine-mediated signaling pathway	6.277049e-5
GO:0035088	establishment or maintenance of apical/basal cell polarity	6.322086e-5
GO:0060916	mesenchymal cell proliferation involved in lung development	6.351067e-5
GO:0006928	cellular component movement	6.373946e-5
GO:0071206	establishment of protein localization to juxtaparanode region of axon	6.595659e-5
GO:0060168	positive regulation of adenosine receptor signaling pathway	6.595659e-5
GO:0035590	purinergic nucleotide receptor signaling pathway	6.661796e-5
GO:0060080	regulation of inhibitory postsynaptic membrane potential	6.672348e-5
GO:0007435	salivary gland morphogenesis	6.735978e-5
GO:0071229	cellular response to acid	6.927685e-5
GO:0090066	regulation of anatomical structure size	7.052168e-5
GO:0009966	regulation of signal transduction	7.084956e-5
GO:0006633	fatty acid biosynthetic process	7.169146e-5
GO:0002444	myeloid leukocyte mediated immunity	7.235721e-5
GO:0010424	DNA methylation on cytosine within a CG sequence	7.276804e-5
GO:0070887	cellular response to chemical stimulus	7.487801e-5
GO:0006886	intracellular protein transport	7.588998e-5
GO:0007204	elevation of cytosolic calcium ion concentration	7.730193e-5
GO:0070661	leukocyte proliferation	7.804209e-5
GO:0044260	cellular macromolecule metabolic process	7.875059e-5
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	7.978057e-5
GO:0016050	vesicle organization	8.378623e-5
GO:0060193	positive regulation of lipase activity	8.444154e-5
GO:0040011	locomotion	8.728246e-5
GO:0050877	neurological system process	8.995613e-5
GO:0071842	cellular component organization at cellular level	9.497161e-5
GO:0010001	glial cell differentiation	9.501379e-5
GO:0032776	DNA methylation on cytosine	1.004088e-4
GO:0032787	monocarboxylic acid metabolic process	1.014246e-4
GO:0015936	coenzyme A metabolic process	1.032612e-4
GO:0061039	ovum-producing ovary development	1.054375e-4
GO:0007049	cell cycle	1.054499e-4
GO:0018210	peptidyl-threonine modification	1.062849e-4
GO:0051901	positive regulation of mitochondrial depolarization	1.069081e-4
GO:0048143	astrocyte activation	1.123540e-4
GO:0051329	interphase of mitotic cell cycle	1.129439e-4
GO:0001914	regulation of T cell mediated cytotoxicity	1.146510e-4
GO:0051480	cytosolic calcium ion homeostasis	1.169585e-4
GO:0071338	positive regulation of hair follicle cell proliferation	1.175592e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.179189e-4
GO:0007596	blood coagulation	1.204713e-4
GO:0051046	regulation of secretion	1.218817e-4
GO:0032429	regulation of phospholipase A2 activity	1.232093e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.232318e-4
GO:0071777	positive regulation of cell cycle cytokinesis	1.236332e-4
GO:0046931	pore complex assembly	1.253645e-4
GO:0042221	response to chemical stimulus	1.265463e-4
GO:0032502	developmental process	1.284978e-4
GO:0006692	prostanoid metabolic process	1.322561e-4
GO:0006693	prostaglandin metabolic process	1.336580e-4
GO:0048871	multicellular organismal homeostasis	1.341086e-4
GO:0048730	epidermis morphogenesis	1.362952e-4
GO:0014056	regulation of acetylcholine secretion	1.382338e-4
GO:0070099	regulation of chemokine-mediated signaling pathway	1.391595e-4
GO:0009620	response to fungus	1.395867e-4
GO:0050714	positive regulation of protein secretion	1.478824e-4
GO:0046326	positive regulation of glucose import	1.489725e-4
GO:0007599	hemostasis	1.509506e-4
GO:0006904	vesicle docking involved in exocytosis	1.511327e-4
GO:0000245	spliceosome assembly	1.512318e-4
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	1.547590e-4
GO:0007052	mitotic spindle organization	1.565181e-4
GO:0006575	cellular modified amino acid metabolic process	1.581458e-4
GO:0060333	interferon-gamma-mediated signaling pathway	1.641588e-4
GO:0031645	negative regulation of neurological system process	1.645344e-4
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	1.733206e-4
GO:0048489	synaptic vesicle transport	1.771559e-4
GO:0034621	cellular macromolecular complex subunit organization	1.794883e-4
GO:0046651	lymphocyte proliferation	1.796467e-4
GO:0019222	regulation of metabolic process	1.817650e-4
GO:0010827	regulation of glucose transport	1.820757e-4
GO:0046498	S-adenosylhomocysteine metabolic process	1.828064e-4
GO:0045066	regulatory T cell differentiation	1.828064e-4
GO:0042098	T cell proliferation	1.844826e-4
GO:0035058	nonmotile primary cilium assembly	1.868021e-4
GO:0006954	inflammatory response	1.884806e-4
GO:0045821	positive regulation of glycolysis	1.901322e-4
GO:0001894	tissue homeostasis	1.916666e-4
GO:0022037	metencephalon development	1.932836e-4
GO:0009611	response to wounding	1.936064e-4
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.937439e-4
GO:0051905	establishment of pigment granule localization	1.965422e-4
GO:0006112	energy reserve metabolic process	1.970057e-4
GO:0031644	regulation of neurological system process	2.012660e-4
GO:0005976	polysaccharide metabolic process	2.052258e-4
GO:0034641	cellular nitrogen compound metabolic process	2.129418e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.138444e-4
GO:0071822	protein complex subunit organization	2.152308e-4
GO:0045216	cell-cell junction organization	2.152826e-4
GO:0043163	cell envelope organization	2.170754e-4
GO:0009063	cellular amino acid catabolic process	2.215991e-4
GO:0015937	coenzyme A biosynthetic process	2.242047e-4
GO:0014916	regulation of lung blood pressure	2.247731e-4
GO:0000395	nuclear mRNA 5'-splice site recognition	2.283514e-4
GO:0060191	regulation of lipase activity	2.372448e-4
GO:0051904	pigment granule transport	2.383573e-4
GO:0051325	interphase	2.478986e-4
GO:0071310	cellular response to organic substance	2.527061e-4
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	2.618908e-4
GO:0090136	epithelial cell-cell adhesion	2.624757e-4
GO:0006397	mRNA processing	2.650992e-4
GO:0055114	oxidation-reduction process	2.659938e-4
GO:0005977	glycogen metabolic process	2.660287e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	2.678760e-4
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.702893e-4
GO:0034330	cell junction organization	2.775861e-4
GO:0031557	induction of programmed cell death in response to chemical stimulus	2.787617e-4
GO:0000018	regulation of DNA recombination	2.819180e-4
GO:0009116	nucleoside metabolic process	2.857310e-4
GO:0048168	regulation of neuronal synaptic plasticity	2.871398e-4
GO:0050878	regulation of body fluid levels	2.984600e-4
GO:0007215	glutamate signaling pathway	3.004634e-4
GO:0051150	regulation of smooth muscle cell differentiation	3.086391e-4
GO:0009249	protein lipoylation	3.100714e-4
GO:0008585	female gonad development	3.106725e-4
GO:0051966	regulation of synaptic transmission, glutamatergic	3.112027e-4
GO:0046732	active induction of host immune response by virus	3.158775e-4
GO:0006936	muscle contraction	3.171117e-4
GO:0009310	amine catabolic process	3.205534e-4
GO:0030719	P granule organization	3.275351e-4
GO:0001817	regulation of cytokine production	3.318289e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	3.509715e-4
GO:0034063	stress granule assembly	3.522916e-4
GO:0000272	polysaccharide catabolic process	3.634503e-4
GO:0035385	Roundabout signaling pathway	3.656471e-4
GO:0051967	negative regulation of synaptic transmission, glutamatergic	3.702593e-4
GO:0002244	hemopoietic progenitor cell differentiation	3.769192e-4
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	3.823827e-4
GO:0048518	positive regulation of biological process	3.865833e-4
GO:0006873	cellular ion homeostasis	3.873942e-4
GO:0010863	positive regulation of phospholipase C activity	3.900313e-4
GO:0050808	synapse organization	3.920573e-4
GO:0006591	ornithine metabolic process	3.938883e-4
GO:0090311	regulation of protein deacetylation	3.961321e-4
GO:0032409	regulation of transporter activity	3.982255e-4
GO:0060789	hair follicle placode formation	4.015982e-4
GO:0006110	regulation of glycolysis	4.027352e-4
GO:0051881	regulation of mitochondrial membrane potential	4.033672e-4
GO:0044283	small molecule biosynthetic process	4.114501e-4
GO:0006551	leucine metabolic process	4.153150e-4
GO:0046314	phosphocreatine biosynthetic process	4.153150e-4
GO:0043900	regulation of multi-organism process	4.198906e-4
GO:0042559	pteridine-containing compound biosynthetic process	4.231923e-4
GO:0090231	regulation of spindle checkpoint	4.235349e-4
GO:0070207	protein homotrimerization	4.245531e-4
GO:0007202	activation of phospholipase C activity	4.275004e-4
GO:0035815	positive regulation of renal sodium excretion	4.407344e-4
GO:0006073	cellular glucan metabolic process	4.418158e-4
GO:0031063	regulation of histone deacetylation	4.435830e-4
GO:0051899	membrane depolarization	4.494357e-4
GO:0006949	syncytium formation	4.518274e-4
GO:0007431	salivary gland development	4.652669e-4
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	4.780464e-4
GO:0048741	skeletal muscle fiber development	4.786643e-4
GO:0090381	regulation of heart induction	4.834385e-4
GO:0051602	response to electrical stimulus	4.933725e-4
GO:0002720	positive regulation of cytokine production involved in immune response	5.121517e-4
GO:0002446	neutrophil mediated immunity	5.123584e-4
GO:0003012	muscle system process	5.155048e-4
GO:0050805	negative regulation of synaptic transmission	5.192337e-4
GO:0006508	proteolysis	5.228344e-4
GO:0060081	membrane hyperpolarization	5.364150e-4
GO:0001906	cell killing	5.395566e-4
GO:0006914	autophagy	5.497908e-4
GO:0006479	protein methylation	5.744389e-4
GO:0032886	regulation of microtubule-based process	5.768093e-4
GO:0030185	nitric oxide transport	5.820755e-4
GO:0007275	multicellular organismal development	5.850862e-4
GO:0015980	energy derivation by oxidation of organic compounds	5.885938e-4
GO:0031326	regulation of cellular biosynthetic process	5.908374e-4
GO:0051128	regulation of cellular component organization	5.936647e-4
GO:0018126	protein hydroxylation	5.976846e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	6.017298e-4
GO:0048610	cellular process involved in reproduction	6.088701e-4
GO:0045907	positive regulation of vasoconstriction	6.105096e-4
GO:0048599	oocyte development	6.107707e-4
GO:0042118	endothelial cell activation	6.114268e-4
GO:0008366	axon ensheathment	6.217720e-4
GO:0042743	hydrogen peroxide metabolic process	6.260196e-4
GO:0006651	diacylglycerol biosynthetic process	6.307409e-4
GO:0000296	spermine transport	6.307409e-4
GO:0002274	myeloid leukocyte activation	6.309146e-4
GO:0002456	T cell mediated immunity	6.387756e-4
GO:0016265	death	6.421053e-4
GO:0018107	peptidyl-threonine phosphorylation	6.421749e-4
GO:0050777	negative regulation of immune response	6.468054e-4
GO:0001542	ovulation from ovarian follicle	6.486160e-4
GO:0031328	positive regulation of cellular biosynthetic process	6.501853e-4
GO:0032467	positive regulation of cytokinesis	6.523253e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	6.530144e-4
GO:0050688	regulation of defense response to virus	6.577029e-4
GO:0006797	polyphosphate metabolic process	6.629812e-4
GO:0050665	hydrogen peroxide biosynthetic process	6.692606e-4
GO:0050708	regulation of protein secretion	6.804262e-4
GO:0001666	response to hypoxia	6.921863e-4
GO:0072657	protein localization in membrane	6.926456e-4
GO:0006887	exocytosis	7.095530e-4
GO:0007520	myoblast fusion	7.142417e-4
GO:0014048	regulation of glutamate secretion	7.243527e-4
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	7.304209e-4
GO:0008219	cell death	7.305507e-4
GO:0051336	regulation of hydrolase activity	7.548025e-4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	7.587675e-4
GO:0045060	negative thymic T cell selection	7.986760e-4
GO:0060167	regulation of adenosine receptor signaling pathway	7.987924e-4
GO:0031536	positive regulation of exit from mitosis	7.999006e-4
GO:0034329	cell junction assembly	8.063972e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0035645	enteric smooth muscle cell differentiation	3.696429e-13
GO:0007497	posterior midgut development	3.696429e-13
GO:0048246	macrophage chemotaxis	1.167552e-11
GO:0060346	bone trabecula formation	2.411850e-9
GO:0006611	protein export from nucleus	4.005422e-9
GO:0014043	negative regulation of neuron maturation	4.801884e-8
GO:0014826	vein smooth muscle contraction	4.893189e-8
GO:0032753	positive regulation of interleukin-4 production	6.966623e-8
GO:0043368	positive T cell selection	8.605145e-8
GO:0045059	positive thymic T cell selection	8.846940e-8
GO:0014041	regulation of neuron maturation	2.650358e-7
GO:0007160	cell-matrix adhesion	4.592622e-7
GO:0051049	regulation of transport	4.942834e-7
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	6.746890e-7
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	6.746890e-7
GO:0061141	lung ciliated cell differentiation	6.746890e-7
GO:0021740	principal sensory nucleus of trigeminal nerve development	6.746890e-7
GO:0031914	negative regulation of synaptic plasticity	7.432572e-7
GO:0002035	brain renin-angiotensin system	7.738285e-7
GO:0007600	sensory perception	8.547465e-7
GO:0021960	anterior commissure morphogenesis	1.198604e-6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.276009e-6
GO:0071300	cellular response to retinoic acid	1.605073e-6
GO:0008202	steroid metabolic process	1.675672e-6
GO:0032879	regulation of localization	1.834616e-6
GO:0002709	regulation of T cell mediated immunity	1.994989e-6
GO:0016042	lipid catabolic process	2.041311e-6
GO:0045058	T cell selection	2.345141e-6
GO:0071299	cellular response to vitamin A	2.393165e-6
GO:0006811	ion transport	3.010748e-6
GO:0001974	blood vessel remodeling	3.185091e-6
GO:0001887	selenium compound metabolic process	4.450155e-6
GO:0016142	O-glycoside catabolic process	4.524836e-6
GO:0030728	ovulation	5.704652e-6
GO:0034505	tooth mineralization	6.003413e-6
GO:0070588	calcium ion transmembrane transport	7.107871e-6
GO:0042592	homeostatic process	7.279032e-6
GO:0045061	thymic T cell selection	7.832920e-6
GO:0072329	monocarboxylic acid catabolic process	8.145124e-6
GO:0002686	negative regulation of leukocyte migration	9.655413e-6
GO:0045577	regulation of B cell differentiation	9.689768e-6
GO:0002757	immune response-activating signal transduction	9.914677e-6
GO:0010625	positive regulation of Schwann cell proliferation	1.042649e-5
GO:0002016	regulation of blood volume by renin-angiotensin	1.138438e-5
GO:0046395	carboxylic acid catabolic process	1.183168e-5
GO:0050778	positive regulation of immune response	1.255123e-5
GO:0051239	regulation of multicellular organismal process	1.305684e-5
GO:0050852	T cell receptor signaling pathway	1.306879e-5
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.354804e-5
GO:0050851	antigen receptor-mediated signaling pathway	1.647281e-5
GO:0032661	regulation of interleukin-18 production	1.678001e-5
GO:0033136	serine phosphorylation of STAT3 protein	1.678001e-5
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.732208e-5
GO:0006939	smooth muscle contraction	1.736163e-5
GO:0002820	negative regulation of adaptive immune response	2.149023e-5
GO:0060676	ureteric bud formation	2.149028e-5
GO:0032963	collagen metabolic process	2.152830e-5
GO:0071230	cellular response to amino acid stimulus	2.513159e-5
GO:0061383	trabecula morphogenesis	2.521394e-5
GO:0002768	immune response-regulating cell surface receptor signaling pathway	2.591563e-5
GO:0007422	peripheral nervous system development	2.672075e-5
GO:0060343	trabecula formation	2.695799e-5
GO:0014821	phasic smooth muscle contraction	2.715116e-5
GO:0007494	midgut development	2.723154e-5
GO:0001542	ovulation from ovarian follicle	2.723154e-5
GO:0048753	pigment granule organization	2.723334e-5
GO:0044259	multicellular organismal macromolecule metabolic process	2.763444e-5
GO:0001957	intramembranous ossification	2.907077e-5
GO:0002764	immune response-regulating signaling pathway	2.919142e-5
GO:0032438	melanosome organization	3.029552e-5
GO:0050832	defense response to fungus	3.435471e-5
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	3.589630e-5
GO:0048857	neural nucleus development	3.589630e-5
GO:0045332	phospholipid translocation	3.594454e-5
GO:0043200	response to amino acid stimulus	3.600265e-5
GO:0031589	cell-substrate adhesion	3.601733e-5
GO:0046635	positive regulation of alpha-beta T cell activation	3.924300e-5
GO:0002253	activation of immune response	4.019334e-5
GO:0050776	regulation of immune response	4.057631e-5
GO:0010833	telomere maintenance via telomere lengthening	4.114576e-5
GO:0002684	positive regulation of immune system process	4.133257e-5
GO:0006582	melanin metabolic process	4.133935e-5
GO:0048488	synaptic vesicle endocytosis	4.181833e-5
GO:0006198	cAMP catabolic process	4.186293e-5
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	4.220597e-5
GO:0045621	positive regulation of lymphocyte differentiation	4.509264e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	4.540083e-5
GO:0019932	second-messenger-mediated signaling	4.744034e-5
GO:0042438	melanin biosynthetic process	4.800005e-5
GO:0043473	pigmentation	5.011436e-5
GO:0043113	receptor clustering	5.175511e-5
GO:0070309	lens fiber cell morphogenesis	5.633469e-5
GO:0071229	cellular response to acid	6.022864e-5
GO:0071347	cellular response to interleukin-1	6.076386e-5
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	6.242049e-5
GO:0051291	protein heterooligomerization	6.278926e-5
GO:0051127	positive regulation of actin nucleation	6.332775e-5
GO:0002019	regulation of renal output by angiotensin	6.332775e-5
GO:0006886	intracellular protein transport	6.343597e-5
GO:0060012	synaptic transmission, glycinergic	6.580635e-5
GO:0046058	cAMP metabolic process	7.163402e-5
GO:0001958	endochondral ossification	7.180829e-5
GO:0045582	positive regulation of T cell differentiation	7.299460e-5
GO:0072657	protein localization in membrane	7.436290e-5
GO:0045656	negative regulation of monocyte differentiation	7.771800e-5
GO:0014829	vascular smooth muscle contraction	7.790925e-5
GO:0006820	anion transport	7.841683e-5
GO:0032383	regulation of intracellular cholesterol transport	8.200499e-5
GO:0015939	pantothenate metabolic process	8.200499e-5
GO:0016140	O-glycoside metabolic process	8.200499e-5
GO:0009062	fatty acid catabolic process	8.203281e-5
GO:0071295	cellular response to vitamin	8.604325e-5
GO:0042339	keratan sulfate metabolic process	8.926870e-5
GO:0007004	telomere maintenance via telomerase	8.960831e-5
GO:0060078	regulation of postsynaptic membrane potential	9.004327e-5
GO:0071679	commissural neuron axon guidance	9.388000e-5
GO:0032801	receptor catabolic process	9.661650e-5
GO:0009187	cyclic nucleotide metabolic process	9.959460e-5
GO:0019935	cyclic-nucleotide-mediated signaling	1.099081e-4
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	1.142637e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	1.158230e-4
GO:0048484	enteric nervous system development	1.206858e-4
GO:0032689	negative regulation of interferon-gamma production	1.230511e-4
GO:0001101	response to acid	1.367152e-4
GO:0017156	calcium ion-dependent exocytosis	1.444169e-4
GO:0001820	serotonin secretion	1.457210e-4
GO:0046634	regulation of alpha-beta T cell activation	1.477483e-4
GO:0043383	negative T cell selection	1.674174e-4
GO:0010883	regulation of lipid storage	1.697777e-4
GO:0048066	developmental pigmentation	1.717930e-4
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	1.757868e-4
GO:0033059	cellular pigmentation	1.785935e-4
GO:0045579	positive regulation of B cell differentiation	1.831355e-4
GO:0009125	nucleoside monophosphate catabolic process	1.832032e-4
GO:0032464	positive regulation of protein homooligomerization	1.860818e-4
GO:0019585	glucuronate metabolic process	1.881370e-4
GO:0042940	D-amino acid transport	1.885529e-4
GO:0032673	regulation of interleukin-4 production	1.915827e-4
GO:0034104	negative regulation of tissue remodeling	1.922941e-4
GO:0048251	elastic fiber assembly	1.938332e-4
GO:0070947	neutrophil mediated killing of fungus	1.945007e-4
GO:0042840	D-glucuronate catabolic process	2.032019e-4
GO:0019428	allantoin biosynthetic process	2.032019e-4
GO:0022610	biological adhesion	2.148865e-4
GO:0050870	positive regulation of T cell activation	2.172903e-4
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	2.210988e-4
GO:0050954	sensory perception of mechanical stimulus	2.266861e-4
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	2.291155e-4
GO:0071514	genetic imprinting	2.296405e-4
GO:0019233	sensory perception of pain	2.360913e-4
GO:0002703	regulation of leukocyte mediated immunity	2.472253e-4
GO:0043001	Golgi to plasma membrane protein transport	2.547645e-4
GO:0031670	cellular response to nutrient	2.579737e-4
GO:0051386	regulation of nerve growth factor receptor signaling pathway	2.582119e-4
GO:0042312	regulation of vasodilation	2.592334e-4
GO:0070838	divalent metal ion transport	2.640714e-4
GO:0043269	regulation of ion transport	2.685496e-4
GO:0019276	UDP-N-acetylgalactosamine metabolic process	2.697092e-4
GO:0030318	melanocyte differentiation	2.700903e-4
GO:0072521	purine-containing compound metabolic process	2.799798e-4
GO:0002711	positive regulation of T cell mediated immunity	3.143538e-4
GO:0002706	regulation of lymphocyte mediated immunity	3.153798e-4
GO:0030001	metal ion transport	3.223250e-4
GO:0072511	divalent inorganic cation transport	3.251034e-4
GO:0060509	Type I pneumocyte differentiation	3.320743e-4
GO:0009214	cyclic nucleotide catabolic process	3.379906e-4
GO:0048878	chemical homeostasis	3.577569e-4
GO:0046640	regulation of alpha-beta T cell proliferation	3.620486e-4
GO:0071260	cellular response to mechanical stimulus	3.710013e-4
GO:0006629	lipid metabolic process	3.795058e-4
GO:0043604	amide biosynthetic process	3.822354e-4
GO:0006810	transport	3.928166e-4
GO:0014065	phosphatidylinositol 3-kinase cascade	4.074058e-4
GO:0050877	neurological system process	4.139093e-4
GO:0050931	pigment cell differentiation	4.147943e-4
GO:0019933	cAMP-mediated signaling	4.190833e-4
GO:0007155	cell adhesion	4.223971e-4
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	4.225760e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	4.249166e-4
GO:0043525	positive regulation of neuron apoptosis	4.326246e-4
GO:0051145	smooth muscle cell differentiation	4.404193e-4
GO:0007632	visual behavior	4.417914e-4
GO:0007605	sensory perception of sound	4.504520e-4
GO:0048538	thymus development	4.527969e-4
GO:0045956	positive regulation of calcium ion-dependent exocytosis	4.657818e-4
GO:0051234	establishment of localization	4.873085e-4
GO:0050900	leukocyte migration	4.928342e-4
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	5.323747e-4
GO:0010951	negative regulation of endopeptidase activity	5.451147e-4
GO:0071320	cellular response to cAMP	5.470813e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.473306e-4
GO:0016337	cell-cell adhesion	5.487236e-4
GO:0007292	female gamete generation	5.540614e-4
GO:0060406	positive regulation of penile erection	5.578824e-4
GO:0002699	positive regulation of immune effector process	5.662976e-4
GO:0010959	regulation of metal ion transport	5.860074e-4
GO:0045619	regulation of lymphocyte differentiation	6.081323e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	6.103113e-4
GO:0052572	response to host immune response	6.138372e-4
GO:0010667	negative regulation of cardiac muscle cell apoptosis	6.173911e-4
GO:0002920	regulation of humoral immune response	6.195071e-4
GO:0060416	response to growth hormone stimulus	6.262677e-4
GO:0001915	negative regulation of T cell mediated cytotoxicity	6.304596e-4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	6.338345e-4
GO:0048034	heme O biosynthetic process	6.338345e-4
GO:0032741	positive regulation of interleukin-18 production	6.338345e-4
GO:0018364	peptidyl-glutamine methylation	6.338345e-4
GO:0052556	positive regulation by symbiont of host immune response	6.505667e-4
GO:0052509	positive regulation by symbiont of host defense response	6.505667e-4
GO:0042501	serine phosphorylation of STAT protein	6.505667e-4
GO:0070943	neutrophil mediated killing of symbiont cell	6.507949e-4
GO:0030259	lipid glycosylation	6.543805e-4
GO:0051168	nuclear export	6.661758e-4
GO:0035249	synaptic transmission, glutamatergic	6.772513e-4
GO:0051125	regulation of actin nucleation	6.819474e-4
GO:0045872	positive regulation of rhodopsin gene expression	6.907890e-4
GO:0046034	ATP metabolic process	7.019061e-4
GO:0051923	sulfation	7.070844e-4
GO:0051251	positive regulation of lymphocyte activation	7.208160e-4
GO:0006837	serotonin transport	8.018998e-4
GO:0030534	adult behavior	8.126096e-4
GO:0006163	purine nucleotide metabolic process	8.539808e-4
GO:0009605	response to external stimulus	8.606718e-4
GO:0055088	lipid homeostasis	8.671800e-4
GO:0060627	regulation of vesicle-mediated transport	8.733674e-4
GO:0060079	regulation of excitatory postsynaptic membrane potential	9.109579e-4
GO:0071224	cellular response to peptidoglycan	9.391150e-4
GO:0001544	initiation of primordial ovarian follicle growth	9.391150e-4
GO:0001754	eye photoreceptor cell differentiation	9.473076e-4
GO:0010665	regulation of cardiac muscle cell apoptosis	9.554651e-4
GO:0030449	regulation of complement activation	9.767474e-4
GO:0070555	response to interleukin-1	9.771094e-4
GO:0007194	negative regulation of adenylate cyclase activity	9.773875e-4
GO:0085029	extracellular matrix assembly	9.861080e-4
GO:0015031	protein transport	9.871053e-4
GO:0045060	negative thymic T cell selection	1.010489e-3
GO:0002821	positive regulation of adaptive immune response	1.015100e-3
GO:0097035	regulation of membrane lipid distribution	1.019819e-3
GO:0006816	calcium ion transport	1.030198e-3
GO:0010884	positive regulation of lipid storage	1.049188e-3
GO:0006493	protein O-linked glycosylation	1.049188e-3
GO:0071417	cellular response to organic nitrogen	1.067161e-3
GO:0051952	regulation of amine transport	1.083145e-3
GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	1.091221e-3
GO:0032526	response to retinoic acid	1.098111e-3
GO:0051414	response to cortisol stimulus	1.104953e-3
GO:0071418	cellular response to amine stimulus	1.104987e-3
GO:0006306	DNA methylation	1.124492e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	1.161202e-3
GO:0001556	oocyte maturation	1.199860e-3
GO:0002710	negative regulation of T cell mediated immunity	1.210316e-3
GO:0046530	photoreceptor cell differentiation	1.231046e-3
GO:0071548	response to dexamethasone stimulus	1.233708e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	1.234309e-3
GO:0006635	fatty acid beta-oxidation	1.234309e-3
GO:0045109	intermediate filament organization	1.253950e-3
GO:0065009	regulation of molecular function	1.260655e-3
GO:0021615	glossopharyngeal nerve morphogenesis	1.305430e-3
GO:0001869	negative regulation of complement activation, lectin pathway	1.305430e-3
GO:0000723	telomere maintenance	1.326510e-3
GO:0001914	regulation of T cell mediated cytotoxicity	1.332158e-3
GO:0006893	Golgi to plasma membrane transport	1.371039e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.377556e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	1.387416e-3
GO:0030277	maintenance of gastrointestinal epithelium	1.387803e-3
GO:0017004	cytochrome complex assembly	1.387803e-3
GO:0034613	cellular protein localization	1.402970e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	1.409071e-3
GO:0002034	regulation of blood vessel size by renin-angiotensin	1.415773e-3
GO:0003051	angiotensin-mediated drinking behavior	1.415773e-3
GO:0042632	cholesterol homeostasis	1.457679e-3
GO:2000026	regulation of multicellular organismal development	1.491843e-3
GO:0034241	positive regulation of macrophage fusion	1.502501e-3
GO:0070727	cellular macromolecule localization	1.505629e-3
GO:0002819	regulation of adaptive immune response	1.510053e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	1.537659e-3
GO:0032649	regulation of interferon-gamma production	1.555012e-3
GO:0007166	cell surface receptor linked signaling pathway	1.570425e-3
GO:0030574	collagen catabolic process	1.573771e-3
GO:0034220	ion transmembrane transport	1.580897e-3
GO:0002682	regulation of immune system process	1.680860e-3
GO:0043603	cellular amide metabolic process	1.721544e-3
GO:0007154	cell communication	1.729594e-3
GO:0050777	negative regulation of immune response	1.746573e-3
GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	1.774523e-3
GO:0046958	nonassociative learning	1.774523e-3
GO:0010975	regulation of neuron projection development	1.782638e-3
GO:0006821	chloride transport	1.788851e-3
GO:0042462	eye photoreceptor cell development	1.792876e-3
GO:0010886	positive regulation of cholesterol storage	1.801714e-3
GO:0032490	detection of molecule of bacterial origin	1.827828e-3
GO:0060486	Clara cell differentiation	1.834334e-3
GO:0002726	positive regulation of T cell cytokine production	1.887362e-3
GO:0046851	negative regulation of bone remodeling	1.887362e-3
GO:0044236	multicellular organismal metabolic process	1.896210e-3
GO:0040032	post-embryonic body morphogenesis	1.947749e-3
GO:0070208	protein heterotrimerization	1.972292e-3
GO:0042440	pigment metabolic process	1.973524e-3
GO:0070779	D-aspartate import	1.985627e-3
GO:0051924	regulation of calcium ion transport	2.050040e-3
GO:0002442	serotonin secretion involved in inflammatory response	2.087758e-3
GO:0032318	regulation of Ras GTPase activity	2.106724e-3
GO:0000722	telomere maintenance via recombination	2.146333e-3
GO:0010830	regulation of myotube differentiation	2.186243e-3
GO:0044242	cellular lipid catabolic process	2.261604e-3
GO:0060020	Bergmann glial cell differentiation	2.265239e-3
GO:0071827	plasma lipoprotein particle organization	2.325594e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	2.327129e-3
GO:0042941	D-alanine transport	2.327129e-3
GO:0017187	peptidyl-glutamic acid carboxylation	2.327129e-3
GO:0006605	protein targeting	2.327171e-3
GO:0001779	natural killer cell differentiation	2.351477e-3
GO:0060427	lung connective tissue development	2.364504e-3
GO:0006438	valyl-tRNA aminoacylation	2.364504e-3
GO:0006680	glucosylceramide catabolic process	2.364504e-3
GO:0042461	photoreceptor cell development	2.383570e-3
GO:0035058	nonmotile primary cilium assembly	2.395666e-3
GO:0030833	regulation of actin filament polymerization	2.398316e-3
GO:0044057	regulation of system process	2.450256e-3
GO:0030838	positive regulation of actin filament polymerization	2.476867e-3
GO:0023052	signaling	2.497440e-3
GO:0050850	positive regulation of calcium-mediated signaling	2.507212e-3
GO:0045184	establishment of protein localization	2.553113e-3
GO:0010717	regulation of epithelial to mesenchymal transition	2.583084e-3
GO:0003008	system process	2.586624e-3
GO:0060249	anatomical structure homeostasis	2.605041e-3
GO:0006892	post-Golgi vesicle-mediated transport	2.632762e-3
GO:0042310	vasoconstriction	2.645615e-3
GO:0007252	I-kappaB phosphorylation	2.657348e-3
GO:0009123	nucleoside monophosphate metabolic process	2.707040e-3
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	2.730978e-3
GO:0051588	regulation of neurotransmitter transport	2.734221e-3
GO:0015698	inorganic anion transport	2.744753e-3
GO:0006022	aminoglycan metabolic process	2.760601e-3
GO:0006936	muscle contraction	2.761437e-3
GO:0002724	regulation of T cell cytokine production	2.792511e-3
GO:0044003	modification by symbiont of host morphology or physiology	2.856528e-3
GO:0050871	positive regulation of B cell activation	2.888988e-3
GO:0043547	positive regulation of GTPase activity	2.957170e-3
GO:0033077	T cell differentiation in thymus	3.063304e-3
GO:0002329	pre-B cell differentiation	3.095412e-3
GO:0032200	telomere organization	3.122962e-3
GO:0045580	regulation of T cell differentiation	3.149107e-3
GO:0097006	regulation of plasma lipoprotein particle levels	3.156601e-3
GO:0051249	regulation of lymphocyte activation	3.160057e-3
GO:0050848	regulation of calcium-mediated signaling	3.202968e-3
GO:0071221	cellular response to bacterial lipopeptide	3.214999e-3
GO:0015851	nucleobase transport	3.214999e-3
GO:0050863	regulation of T cell activation	3.240172e-3
GO:0046185	aldehyde catabolic process	3.243795e-3
GO:0002897	positive regulation of central B cell tolerance induction	3.243795e-3
GO:0002508	central tolerance induction	3.243795e-3
GO:0051046	regulation of secretion	3.252597e-3
GO:0071400	cellular response to oleic acid	3.279427e-3
GO:0050801	ion homeostasis	3.287801e-3
GO:0032700	negative regulation of interleukin-17 production	3.318271e-3
GO:0055091	phospholipid homeostasis	3.331547e-3
GO:0019433	triglyceride catabolic process	3.435238e-3
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.440319e-3
GO:0060324	face development	3.448797e-3
GO:0002669	positive regulation of T cell anergy	3.652837e-3
GO:0031343	positive regulation of cell killing	3.697452e-3
GO:0070409	carbamoyl phosphate biosynthetic process	3.698796e-3
GO:0006897	endocytosis	3.706427e-3
GO:0001502	cartilage condensation	3.714105e-3
GO:0008045	motor axon guidance	3.757481e-3
GO:0006687	glycosphingolipid metabolic process	3.757481e-3
GO:0032851	positive regulation of Rab GTPase activity	3.778425e-3
GO:0051147	regulation of muscle cell differentiation	3.798977e-3
GO:0060325	face morphogenesis	3.837298e-3
GO:0090066	regulation of anatomical structure size	3.866880e-3
GO:0007165	signal transduction	3.906135e-3
GO:0006863	purine base transport	3.922300e-3
GO:0044027	hypermethylation of CpG island	3.922300e-3
GO:0007527	adult somatic muscle development	3.976497e-3
GO:0050773	regulation of dendrite development	3.983408e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	3.985067e-3
GO:0048541	Peyer's patch development	3.986197e-3
GO:0048148	behavioral response to cocaine	4.024549e-3
GO:0031098	stress-activated protein kinase signaling cascade	4.040432e-3
GO:0045909	positive regulation of vasodilation	4.055923e-3
GO:0003014	renal system process	4.071987e-3
GO:0032313	regulation of Rab GTPase activity	4.104579e-3
GO:0052200	response to host defenses	4.144933e-3
GO:0032736	positive regulation of interleukin-13 production	4.144933e-3
GO:0019748	secondary metabolic process	4.152028e-3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	4.226710e-3
GO:0032320	positive regulation of Ras GTPase activity	4.234552e-3
GO:0001954	positive regulation of cell-matrix adhesion	4.255741e-3
GO:0045658	regulation of neutrophil differentiation	4.304080e-3
GO:0065008	regulation of biological quality	4.322550e-3
GO:0002697	regulation of immune effector process	4.360546e-3
GO:0030036	actin cytoskeleton organization	4.361169e-3
GO:0043087	regulation of GTPase activity	4.416163e-3
GO:0002089	lens morphogenesis in camera-type eye	4.511544e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	4.531188e-3
GO:0008633	activation of pro-apoptotic gene products	4.534498e-3
GO:0060405	regulation of penile erection	4.551899e-3
GO:0090116	C-5 methylation of cytosine	4.567988e-3
GO:0045663	positive regulation of myoblast differentiation	4.586668e-3
GO:0032862	activation of Rho GTPase activity	4.611373e-3
GO:0032501	multicellular organismal process	4.671242e-3
GO:2000110	negative regulation of macrophage apoptosis	4.693774e-3
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	4.693774e-3
GO:0090275	negative regulation of somatostatin secretion	4.693774e-3
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	4.693774e-3
GO:0033124	regulation of GTP catabolic process	4.707923e-3
GO:0030258	lipid modification	4.737744e-3
GO:0006463	steroid hormone receptor complex assembly	4.755740e-3
GO:0010624	regulation of Schwann cell proliferation	4.784136e-3
GO:0060284	regulation of cell development	4.856479e-3
GO:0006812	cation transport	4.885921e-3
GO:0007270	neuron-neuron synaptic transmission	4.932089e-3
GO:0010810	regulation of cell-substrate adhesion	4.975508e-3
GO:0051336	regulation of hydrolase activity	4.990328e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	5.007053e-3
GO:0031000	response to caffeine	5.036485e-3
GO:0034504	protein localization to nucleus	5.037345e-3
GO:0060028	convergent extension involved in axis elongation	5.056755e-3
GO:0070092	regulation of glucagon secretion	5.056755e-3
GO:0002018	renin-angiotensin regulation of aldosterone production	5.056755e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	5.094403e-3
GO:0001889	liver development	5.115363e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.229517e-3
GO:0016125	sterol metabolic process	5.262282e-3
GO:0002922	positive regulation of humoral immune response	5.277034e-3
GO:0045988	negative regulation of striated muscle contraction	5.288270e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	5.309395e-3
GO:0051050	positive regulation of transport	5.343412e-3
GO:0002761	regulation of myeloid leukocyte differentiation	5.394337e-3
GO:0048239	negative regulation of DNA recombination at telomere	5.447210e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	5.447210e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	5.447210e-3
GO:0006430	lysyl-tRNA aminoacylation	5.447210e-3
GO:0032707	negative regulation of interleukin-23 production	5.447210e-3
GO:0045362	positive regulation of interleukin-1 biosynthetic process	5.447210e-3
GO:0051402	neuron apoptosis	5.455843e-3
GO:0055085	transmembrane transport	5.498633e-3
GO:0007044	cell-substrate junction assembly	5.526258e-3
GO:0045137	development of primary sexual characteristics	5.534378e-3
GO:0090381	regulation of heart induction	5.585647e-3
GO:0000072	M phase specific microtubule process	5.585647e-3
GO:0021819	layer formation in cerebral cortex	5.587249e-3
GO:0034113	heterotypic cell-cell adhesion	5.701151e-3
GO:0050433	regulation of catecholamine secretion	5.770858e-3
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	5.872993e-3
GO:0002696	positive regulation of leukocyte activation	5.894596e-3
GO:0007250	activation of NF-kappaB-inducing kinase activity	6.036567e-3
GO:0042421	norepinephrine biosynthetic process	6.135136e-3
GO:0007606	sensory perception of chemical stimulus	6.162813e-3
GO:0042415	norepinephrine metabolic process	6.169528e-3
GO:0032674	regulation of interleukin-5 production	6.192791e-3
GO:0010464	regulation of mesenchymal cell proliferation	6.259618e-3
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	6.269871e-3
GO:0006784	heme a biosynthetic process	6.331099e-3
GO:0051899	membrane depolarization	6.458810e-3
GO:0042448	progesterone metabolic process	6.480830e-3
GO:0032656	regulation of interleukin-13 production	6.480830e-3
GO:0044282	small molecule catabolic process	6.508224e-3
GO:0050953	sensory perception of light stimulus	6.513032e-3
GO:0002689	negative regulation of leukocyte chemotaxis	6.527970e-3
GO:0045796	negative regulation of intestinal cholesterol absorption	6.550553e-3
GO:0070094	positive regulation of glucagon secretion	6.550553e-3
GO:0010949	negative regulation of intestinal phytosterol absorption	6.550553e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	6.608619e-3
GO:0070509	calcium ion import	6.616918e-3
GO:0045408	regulation of interleukin-6 biosynthetic process	6.623764e-3
GO:0010922	positive regulation of phosphatase activity	6.638111e-3
GO:0001952	regulation of cell-matrix adhesion	6.692785e-3
GO:0030199	collagen fibril organization	6.720476e-3
GO:0034369	plasma lipoprotein particle remodeling	6.743792e-3
GO:0015747	urate transport	6.767107e-3
GO:0001543	ovarian follicle rupture	6.767107e-3
GO:0032497	detection of lipopolysaccharide	6.776168e-3
GO:0007159	leukocyte cell-cell adhesion	6.790371e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	6.994577e-3
GO:0001755	neural crest cell migration	7.014660e-3
GO:2000146	negative regulation of cell motility	7.085592e-3
GO:0048641	regulation of skeletal muscle tissue development	7.095973e-3
GO:0001910	regulation of leukocyte mediated cytotoxicity	7.125093e-3
GO:0071549	cellular response to dexamethasone stimulus	7.140243e-3
GO:0046148	pigment biosynthetic process	7.142837e-3
GO:0046464	acylglycerol catabolic process	7.156695e-3
GO:0050867	positive regulation of cell activation	7.165899e-3
GO:0061039	ovum-producing ovary development	7.176275e-3
GO:0032462	regulation of protein homooligomerization	7.214431e-3
GO:0002645	positive regulation of tolerance induction	7.214431e-3
GO:0010243	response to organic nitrogen	7.234785e-3
GO:0042035	regulation of cytokine biosynthetic process	7.256895e-3
GO:0042930	enterobactin transport	7.283858e-3
GO:0033315	meiotic cell cycle DNA replication checkpoint	7.283858e-3
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	7.283858e-3
GO:0010032	meiotic chromosome condensation	7.283858e-3
GO:0052063	induction by symbiont of defense-related host nitric oxide production	7.312208e-3
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	7.312208e-3
GO:0042892	chloramphenicol transport	7.312208e-3
GO:0014805	smooth muscle adaptation	7.312208e-3
GO:0071377	cellular response to glucagon stimulus	7.359158e-3
GO:0051856	adhesion to symbiont	7.359158e-3
GO:0006200	ATP catabolic process	7.371169e-3