FF:14308-155C6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005248 | ||
| | |accession_numbers=CAGE;DRX008036;DRR008908;DRZ000333;DRZ001718;DRZ011683;DRZ013068 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620 | |||
|ancestors_in_disease_facet=DOID:4,DOID:17,DOID:450,DOID:7,DOID:66,DOID:423,DOID:0080000,DOID:11722 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000408,FF:0000350,FF:0000253,FF:0000406,FF:0000667 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
|def= | |||
|expression_enrichment_score=chr1:197886461..197886558,+!p1@LHX9!2.35!224.47!LHX9;;chr9:132427883..132427951,+!p2@PRRX2!1.68!47.41!PRRX2;;chr7:19157248..19157268,-!p1@TWIST1!1.67!123.34!TWIST1;;chr15:57511609..57511651,+!p2@TCF12!1.67!75.92!TCF12;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.50!30.31!HOXC5;;chr5:2751762..2751784,-!p1@IRX2!1.43!26.11!IRX2;;chr5:72744594..72744609,-!p1@FOXD1!1.33!91.53!FOXD1;;chr11:46299199..46299233,+!p1@CREB3L1!1.28!92.43!CREB3L1;;chr9:132427972..132428056,+!p1@PRRX2!1.27!22.81!PRRX2;;chr5:2751785..2751808,-!p2@IRX2!1.22!15.60!IRX2;;chr5:321810..321877,+!p1@AHRR!1.21!47.71!AHRR;;chrY:21906594..21906622,-!p1@KDM5D!1.21!15.30!KDM5D;;chr11:46299539..46299620,+!p2@CREB3L1!1.20!24.91!CREB3L1;;chr2:102091566..102091581,-!p1@RFX8!1.20!14.70!RFX8;;chr19:47523058..47523114,+!p1@NPAS1!1.20!14.70!NPAS1;;chr7:44143925..44143970,+!p1@AEBP1!1.17!302.79!AEBP1;;chr4:174451370..174451387,-!p1@HAND2!1.17!13.80!HAND2;;chr7:44143978..44143989,+!p2@AEBP1!1.15!24.01!AEBP1;;chr17:46682321..46682362,-!p1@HOXB6!1.15!13.20!HOXB6;;chr2:239756671..239756732,+!p1@TWIST2!1.14!41.41!TWIST2;;chr20:55204351..55204377,+!p1@TFAP2C!1.14!16.51!TFAP2C;;chr5:3595977..3595999,+!p1@IRX1!1.14!12.90!IRX1;;chr10:119303078..119303169,+!p2@EMX2!1.14!12.90!EMX2;;chr3:128206762..128206781,-!p2@GATA2!1.13!77.12!GATA2;;chr7:137686763..137686784,-!p5@CREB3L2!1.13!21.91!CREB3L2;;chr3:147111198..147111225,+!p4@ZIC1!1.13!12.60!ZIC1;;chr8:67525443..67525459,-!p2@MYBL1!1.09!17.11!MYBL1;;chr1:170632285..170632309,+!p1@PRRX1!1.09!12.90!PRRX1;;chr15:37392534..37392562,-!p10@MEIS2!1.08!12.00!MEIS2;;chr3:147111231..147111281,+!p3@ZIC1!1.08!11.10!ZIC1;;chr6:10415276..10415341,-!p2@TFAP2A!1.06!12.90!TFAP2A;;chr2:172967242..172967265,-!p2@DLX2!1.06!10.50!DLX2;;chr2:102091144..102091183,-!p2@RFX8!1.04!9.90!RFX8;;chr20:30193083..30193098,+!p1@ID1!1.02!776.64!ID1;;chr12:66218255..66218304,+!p3@HMGA2!1.02!26.11!HMGA2;;chr11:65686802..65686818,+!p6@DRAP1!1.02!16.81!DRAP1;;chr2:172949484..172949522,+!p1@DLX1!1.01!9.30!DLX1;;chr8:93074803..93074845,-!p1@RUNX1T1!1.00!9.00!RUNX1T1;;chr15:37392616..37392638,-!p2@MEIS2!0.99!27.91!MEIS2;;chr11:65687222..65687240,+!p7@DRAP1!0.99!11.40!DRAP1;;chr7:27192185..27192209,-!p1@HOXA3!0.99!8.70!HOXA3;;chr1:197886421..197886432,+!p2@LHX9!0.99!8.70!LHX9;;chr2:176969228..176969260,+!p1@HOXD11!0.97!8.40!HOXD11;;chr8:106330656..106330684,+!p1@ZFPM2!0.96!21.61!ZFPM2;;chr7:27205136..27205164,-!p1@HOXA9!0.96!8.10!HOXA9;;chr12:115121962..115121987,-!p1@TBX3!0.95!69.32!TBX3;;chr6:19837592..19837621,+!p1@ID4!0.95!50.12!ID4;;chr15:37390850..37390909,-!p3@MEIS2!0.95!15.90!MEIS2;;chr16:86544113..86544145,+!p1@FOXF1!0.94!9.60!FOXF1;;chr5:3595961..3595975,+!p3@IRX1!0.94!7.80!IRX1;;chr7:44143997..44144008,+!p3@AEBP1!0.93!9.60!AEBP1;;chr14:24837368..24837401,+!p1@NFATC4!0.92!17.71!NFATC4;;chr15:37392703..37392717,-!p8@MEIS2!0.92!10.50!MEIS2;;chr1:170633348..170633399,+!p2@PRRX1!0.92!10.20!PRRX1;;chr21:36260773..36260804,-!p7@RUNX1!0.92!9.90!RUNX1;;chr2:239756739..239756755,+!p2@TWIST2!0.91!12.60!TWIST2;;chr19:13134772..13134822,+!p2@NFIX!0.91!10.80!NFIX;;chr12:124873357..124873401,-!p1@NCOR2!0.90!84.03!NCOR2;;chr6:10412600..10412637,-!p1@TFAP2A!0.90!12.00!TFAP2A;;chr20:50179368..50179392,-!p2@NFATC2!0.90!9.00!NFATC2;;chr4:174450089..174450153,-!p2@HAND2!0.90!6.90!HAND2;;chr5:3595934..3595957,+!p2@IRX1!0.90!6.90!IRX1;;chr15:37392724..37392757,-!p1@MEIS2!0.89!32.71!MEIS2;;chr15:83953397..83953425,-!p1@BNC1!0.89!7.80!BNC1;;chr22:19748231..19748317,+!p1@TBX1!0.88!6.60!TBX1;;chr12:66218598..66218645,+!p2@HMGA2!0.87!31.51!HMGA2;;chr11:65686732..65686756,+!p2@DRAP1!0.86!28.21!DRAP1;;chr20:51588873..51588953,+!p1@TSHZ2!0.86!8.40!TSHZ2;;chr3:138665937..138665968,-!p1@FOXL2!0.86!6.30!FOXL2;;chr18:22932080..22932170,-!p1@ZNF521!0.85!27.61!ZNF521;;chr15:37392576..37392589,-!p12@MEIS2!0.85!7.50!MEIS2;;chr5:176738887..176738934,-!p1@MXD3!0.84!42.31!MXD3;;chr11:65687362..65687436,+!p3@DRAP1!0.83!27.91!DRAP1;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.83!5.70!HOXC5;;chr3:157824001..157824078,-!p2@SHOX2!0.83!5.70!SHOX2;;chr12:80085061..80085119,-!p6@PAWR!0.82!9.30!PAWR;;chr6:85473156..85473210,-!p2@TBX18!0.82!6.90!TBX18;;chr15:37392593..37392607,-!p13@MEIS2!0.82!6.90!MEIS2;;chr5:72743793..72743855,-!p4@FOXD1!0.82!6.60!FOXD1;;chr3:157823517..157823562,-!p1@SHOX2!0.82!6.00!SHOX2;;chr12:66218378..66218401,+!p6@HMGA2!0.81!8.70!HMGA2;;chr5:43067636..43067674,+!p6@ZNF131!0.81!7.50!ZNF131;;chr6:10412576..10412599,-!p5@TFAP2A!0.81!5.40!TFAP2A;;chr7:27205106..27205134,-!p2@HOXA9!0.81!5.40!HOXA9;;chr11:46316699..46316719,+!p10@CREB3L1!0.81!5.40!CREB3L1;;chr2:66662281..66662308,+!p1@MEIS1!0.80!19.81!MEIS1;;chr12:66218183..66218209,+!p4@HMGA2!0.80!10.80!HMGA2;;chr2:102091478..102091490,-!p3@RFX8!0.79!5.10!RFX8;;chr2:102091514..102091528,-!p6@RFX8!0.79!5.10!RFX8;;chr3:147127142..147127168,+!p1@ZIC1!0.79!5.10!ZIC1;;chr1:197886665..197886732,+!p3@LHX9!0.79!5.10!LHX9;;chr7:27213893..27213954,-!p1@HOXA10!0.79!5.10!HOXA10;;chr8:93074848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;chr19:44617538..44617598,+!p1@ZNF225!0.24!5.40!ZNF225;;chr12:80084737..80084763,-!p3@PAWR!0.24!5.10!PAWR;;chr1:161736140..161736151,+!p3@ATF6!0.24!4.20!ATF6;;chr19:42636586..42636607,-!p1@POU2F2!0.24!3.60!POU2F2;;chr6:15246200..15246214,+!p2@JARID2!0.24!3.60!JARID2;;chr19:37862054..37862110,+!p1@ZNF527!0.24!3.60!ZNF527;;chr15:50647347..50647366,-!p3@GABPB1!0.24!3.30!GABPB1;;chr1:161736125..161736136,+!p5@ATF6!0.24!3.30!ATF6;;chr8:182424..182462,+!p1@ZNF596!0.24!3.30!ZNF596;;chr15:96874244..96874259,+!p5@NR2F2!0.24!3.00!NR2F2;;chr10:38146994..38147039,-!p2@ZNF248!0.24!3.00!ZNF248;;chr19:58951496..58951539,-!p1@ZNF132!0.24!3.00!ZNF132;;chr4:121843985..121844024,-!p2@PRDM5!0.24!2.70!PRDM5;;chr10:44101902..44101932,+!p2@ZNF485!0.24!2.40!ZNF485;;chr10:70320074..70320106,+!p1@TET1!0.24!2.40!TET1;;chr12:53773927..53773943,+!p3@SP1!0.24!2.40!SP1;;chr15:96874063..96874074,+!p10@NR2F2!0.24!2.10!NR2F2;;chr3:40566488..40566502,+!p3@ZNF621!0.24!2.10!ZNF621;;chr5:172484377..172484418,+!p2@C5orf41!0.24!1.80!CREBRF;;chr7:137564372..137564394,-!p7@CREB3L2!0.24!1.80!CREB3L2;;chr19:44598560..44598576,+!p3@ZNF224!0.24!1.80!ZNF224;;chr1:151431811..151431832,-!p3@POGZ!0.24!1.80!POGZ;;chr18:42260059..42260132,+!p1@SETBP1!0.24!1.80!SETBP1;;chr19:12476443..12476467,-!p1@ZNF442!0.24!1.80!ZNF442;;chr15:57210795..57210809,+!p8@TCF12!0.24!1.50!TCF12;;chr16:67063142..67063153,+!p4@CBFB!0.24!1.50!CBFB;;chr19:12444458..12444486,-!p2@ZNF563!0.24!1.50!ZNF563;;chr17:46621311..46621332,-!p8@HOXB2!0.24!1.20!HOXB2;;chr19:12163769..12163798,-!p1@ZNF878!0.24!1.20!ZNF878;;chr6:21594391..21594431,+!p9@SOX4!0.24!1.20!SOX4;;chr8:60031809..60031835,-!p4@TOX!0.24!1.20!TOX;;chr11:62369806..62369837,-!p8@MTA2!0.24!1.20!MTA2;;chr11:707063..707088,-!p4@DEAF1!0.24!1.20!DEAF1;;chr13:46543346..46543367,-!p9@ZC3H13!0.24!1.20!ZC3H13;;chr2:191878812..191878823,-!p2@STAT1!0.24!1.20!STAT1;;chr1:40997363..40997392,+!p2@ZNF684!0.24!1.20!ZNF684;;chr21:36231861..36231877,-!p12@RUNX1!0.24!1.20!RUNX1;;chr15:76629123..76629151,+!p1@ISL2!0.24!0.90!ISL2;;chr6:134273586..134273611,+!p5@TBPL1!0.24!0.90!TBPL1;;chr1:78444738..78444773,-!p1@FUBP1!0.23!165.35!FUBP1;;chr11:85376121..85376181,-!p1@CREBZF!0.23!46.51!CREBZF;;chr14:89029366..89029425,+!p1@ZC3H14!0.23!35.41!ZC3H14;;chr19:53606636..53606692,-!p1@ZNF160!0.23!27.31!ZNF160;;chr1:16302565..16302605,-!p1@ZBTB17!0.23!26.41!ZBTB17;;chr20:62339381..62339428,+!p1@ZGPAT!0.23!24.01!ZGPAT;;chr6:122720765..122720831,+!p1@HSF2!0.23!20.11!HSF2;;chr19:44669221..44669274,+!p1@ZNF226,p1@ZNF234!0.23!15.60!ZNF226;;chr2:231191875..231191918,+!p1@SP140L!0.23!14.40!SP140L;;chr9:35732647..35732678,+!p2@CREB3!0.23!7.80!CREB3;;chr19:35264089..35264146,-!p1@ZNF599!0.23!7.20!ZNF599;;chr17:16557128..16557174,-!p1@ZNF624!0.23!6.30!ZNF624;;chr19:15543565..15543579,-!p2@WIZ!0.23!6.00!WIZ;;chr16:73092898..73092931,-!p1@ZFHX3!0.23!5.10!ZFHX3;;chr3:150126136..150126158,+!p4@TSC22D2!0.23!4.80!TSC22D2;;chr19:58038683..58038736,+!p1@ZNF549!0.23!4.50!ZNF549;;chr15:57210961..57211012,+!p3@TCF12!0.23!4.20!TCF12;;chr18:74534479..74534551,+!p1@ZNF236!0.23!3.90!ZNF236;;chr19:53193790..53193821,-!p3@ZNF83!0.23!3.90!ZNF83;;chr19:59084872..59084920,-!p2@MZF1!0.23!3.30!MZF1;;chr16:86600426..86600441,+!p1@FOXC2!0.23!3.00!FOXC2;;chr10:51572339..51572376,+!p4@NCOA4!0.23!2.70!NCOA4;;chr12:133706820..133706881,-!p1@ZNF891!0.23!2.40!ZNF891;;chr2:157199008..157199023,-!p3@NR4A2!0.23!2.40!NR4A2;;chr2:46524506..46524514,+!p5@EPAS1!0.23!2.10!EPAS1;;chr9:128509635..128509658,+!p2@PBX3!0.23!2.10!PBX3;;chr11:695215..695231,-!p2@DEAF1!0.23!2.10!DEAF1;;chr1:151253991..151254031,+!p2@ZNF687!0.23!2.10!ZNF687;;chr17:7382891..7382905,-!p7@ZBTB4!0.23!1.80!ZBTB4;; | |||
| | |ffid_belonging_in_development=CL:0000134 | ||
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| | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.fractionation.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3%2520%2528nuclear%2520fraction%2529.CNhs12399.14308-155C6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.fractionation.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3%2520%2528nuclear%2520fraction%2529.CNhs12399.14308-155C6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.fractionation.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3%2520%2528nuclear%2520fraction%2529.CNhs12399.14308-155C6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.fractionation.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3%2520%2528nuclear%2520fraction%2529.CNhs12399.14308-155C6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.fractionation.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3%2520%2528nuclear%2520fraction%2529.CNhs12399.14308-155C6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:14308-155C6 | |||
|is_a=EFO:0002091;;FF:0000667 | |||
|is_obsolete= | |||
|library_id=CNhs12399 | |||
|library_id_phase_based=2:CNhs12399 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;14308 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;14308 | |||
|name=Fibroblast - skin dystrophia myotonica, donor3 (nuclear fraction) | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12399,LSID914,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.056986891976762,0,0,0,0,-0.160318030086386,0,-0.07319269919452,0.625607125780302,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0393492263949039,0,0,0,0,0,0.74725316482938,0,0,0.607513984114634,0,0,0,0,0,0,0,0,0,0,0.204169432998994,0,0.250404334520917,0.349797051279434,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.113973783953524,0,0,0,0.245502245490119,0,0,0.349899172698826,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0293536090575774,0,0,0,0,0,0,-0.0461902126114719,0,0,0,-0.0914079762423603,0.0898820404962045,0,0.342494606732724,0,0,0.0159384327158173,0.488276568995884,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.187775379367488,0,0,0,-0.0506760246065907,-0.264514243202634,0,0,0.204169432998994,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,0.0159384327158173,0,0,0.204169432998994,0,0,0,0,0,0.342494606732724,0,0,0.150840251232924,0.056986891976762,0.128072667632138,-0.0295413585699482,0,0,-0.00467355636085201,0,0,0,0,0,0,0.113973783953524,0,0,0.717091194144873,0,-0.0504125515893149,0.0181606380173141,0,0.086150899711127,0,0.056986891976762,0.0925468956200807,0,0.091527936533259,0.274150345655356,0,0,0,0,0.0085753942739711,0,-0.00690569984021695,0.259774438409307,-0.0174421551038127,0.473646371032666,-0.055712496781182,0,0,0,-0.0643002871527384,0.10559467012191,0,0,0.618014118914537,-0.079264902061162,0,0,1.45604072321441,0,-0.454129283705804,0.0286829023925942,0,0.0279089936692832,0,0,0,0,0,0,0,0,0,0,0,0.215838553044422,0.120254203232954,0.188016277844676,0,0,0,-0.311431845127428,0.204169432998994,0,-0.373286155956567,-0.0654625434858667,0.231063354142254,-0.290625530393928,0,-0.302389727009913,-0.0310720545194996,-0.244318387946461,0.0665262369697253,0.195092757361586,0.34159027581569,0,-0.08627943116636,0.347388440464964,-0.00181485376079221,-0.106782881068781,0.0124626551203119,0.182018020678816,0.00347815284669228,0,0,0,0.148785842473846,0,-0.135726528381566,0.336072265975234,0.061996650107793,0.224922750663776,-0.122890509215723,0.0703529678229025,0.217205404931563,-0.0395325284566706,-0.0101936529846716,0,0.103128518244335,-0.0927555212481345,0,-0.031684673702158,0.0149750335359703,-0.443417500374598,-0.0842541778131416,0,-0.483977461810981,0.0456295228761555,0,-0.270870696847763,-0.390309013546984,0,0,-0.236282624138688,0.113973783953524,0,0.0761667438415301,0,0,0.0564058072218827,0.341435957257288,0.165163564962943,0,0.07339668088458,0.181182997056814,-0.073664680396625,0,-0.037653444059306,-0.202170761610805,-0.0499242185005161,-0.292633804596236,0,-0.217061095296131,-0.094502982563967,-0.164990696339003,0.179764080992409,-0.0584468268118252,-0.162173987195833,0.077059425489368,-0.0914079762423603,0.236485418098058,0.0184364428889763,0.937298450412997,0.109666490943669,0.103345247363336,-0.0773392452373781,-0.121017276144977,0.0586739915955301,0,0.48393788496388,0,-0.160417703394735,0,-0.311668184086972,-0.0489827320879344,-0.160473310972391,-0.220048174585308,0,0.0693399516192197,-0.0476603638804782,0,-0.00671286660624404,0,0,0.128448980273656,0.0427746073809132,-0.211650427864589,0.298043844369936,0,-0.0496095844961608,0,0.113973783953524,-0.295867760199691,0.0433400258439068,0,-0.0022755128975471,0.0536581117986094,0.0293536090575774,0.977571834808862,0,0,0.515790427145316,0,0.204169432998994,-0.207908937299542,0.204169432998994,-0.128332304573328,0.144692785031732,0,-0.108622809454255,0,0,-0.063553982011652,0,0.0699291673882955,0,0.113973783953524,0.0926133101339008,0,0,0.056986891976762,0.113973783953524,0.207898469133806,0.113973783953524,0,0,0,0.024026636343448,0,0.0089554771075128,0.0269607291653853,0.0431857963020401,0,-0.084947843235874,0,0,0,0,0,0.159204454024338,0,0,1.1689766009235,0,-0.00904363172289659,0,0,0,0,-0.0115539695544806,0.288214457290582,0.113973783953524,-0.017888922544108,0,0,0,0,0.0278327941643123,0,0,0,0.113973783953524,-0.057730457053664,0.248064620304207,0,0,0,0.772383704992774,0,0,0,0.0422667133986542,-0.0364593567874585,0,0.0810130134133439,0.381026106681213,0,-0.136938971828649,-0.0815818795468414,0.0805112801526716,0.0861632638541465,-0.0117768276014036,0.458406880689942,0,0,-0.147373347836364,0,0,0.160078788628553,0.127965434748618,0.204169432998994,0.0456888355966066,0,0,0,0,0.113973783953524,0,0.0645015512085398,0.102084716499497,0,0,0,0,0,0,0,0,0,0,0.141576020365296,0.355018743253413,0.204169432998994,0,0,0,0,0,0,0.654462054027989,-0.368927414677219,0.056986891976762,0,0,0,0,0,0,0,0.218875089489287,0,0,0,0,0,0.245502245490119,0,0,0,0.113973783953524,1.04704481856161,0,0,-0.07319269919452,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.123319086035448,-0.199694181968175,0,0,0,0,0,0,0,-0.0706638652070964,0,0.204169432998994,0,0,-0.113884373708977,0,0,0,0.558064641222849,0,-0.160318030086386,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.807158908508265,0.19639492378091,0.0298153840360842,-0.0568589461625992,0,0,0.170517262036368,0,0,0,0,0,0,0.07074429247097,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.139408031804147,0.0189715810946007,0,0,0,0,0.204169432998994,0,0,0.74725316482938,0,0,-0.0920328098005262,0,0,0,0,0.491451019385306,0,0.241325385244806,0.609769882901295,-0.0643746293654466,0,0,0,0.0850224593216925,0.113973783953524,0,0,0,0.501520559160997,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0393492263949039,0,0,0,0,0,0,0,0,0,0,0,0,0.171247303366362,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0799624206781073,0.113973783953524,0,0,0,0,0,0,0.204169432998994,0,0,0,0,0,0,0,0,0,0,0,0,0,0.113973783953524,0.553551181984234,0,0,0,-0.213086229657044,0,0,0,0,0,0,0,0,0.398019126518488,0,0,0,0,0,0,0,0,0,0,0,0.113973783953524,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.126612803342099,0,0,0,0,0,0,0,0,0.204169432998994,0,0,0,0,0.349797051279434,0,-0.0843766322300271,0,0,0,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| |||
|rna_box=155 | |||
|rna_catalog_number=custom | |||
|rna_concentration=0.9139 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.15 | |||
|rna_od260/280=2.12 | |||
|rna_position=C6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=155C6 | |||
|rna_weight_ug=22.8475 | |||
|sample_age=18 year old adult | |||
|sample_category=fractionations and perturbations | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=GM03132 | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Coriell | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=DYSTROPHIA MYOTONICA 1; DM1 | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition=nuclear RNA | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.22145459830755e-210!GO:0043226;organelle;3.63686642345053e-179!GO:0043229;intracellular organelle;8.66468589987554e-179!GO:0043231;intracellular membrane-bound organelle;8.22967931072762e-177!GO:0043227;membrane-bound organelle;8.22967931072762e-177!GO:0005737;cytoplasm;1.55920924046063e-157!GO:0044422;organelle part;5.04338577359797e-139!GO:0044446;intracellular organelle part;3.7679333094669e-137!GO:0044444;cytoplasmic part;1.72471062747107e-118!GO:0032991;macromolecular complex;4.20616597811862e-82!GO:0044238;primary metabolic process;4.20616597811862e-82!GO:0043170;macromolecule metabolic process;1.43909057253884e-79!GO:0044237;cellular metabolic process;1.36021915362928e-78!GO:0005515;protein binding;4.60402116797935e-72!GO:0005634;nucleus;5.31781940544599e-71!GO:0044428;nuclear part;2.2533185685084e-69!GO:0043233;organelle lumen;1.17299831642793e-65!GO:0031974;membrane-enclosed lumen;1.17299831642793e-65!GO:0030529;ribonucleoprotein complex;1.29047121884962e-63!GO:0003723;RNA binding;4.41670452731227e-63!GO:0016043;cellular component organization and biogenesis;1.89744025608241e-49!GO:0031090;organelle membrane;7.16979897377643e-49!GO:0019538;protein metabolic process;4.87924959676967e-47!GO:0006396;RNA processing;1.13971968075958e-44!GO:0043234;protein complex;1.87451000534286e-43!GO:0043283;biopolymer metabolic process;2.16896580834419e-43!GO:0031981;nuclear lumen;1.81073979675323e-41!GO:0044260;cellular macromolecule metabolic process;2.99024280237905e-40!GO:0005739;mitochondrion;4.90408840705048e-40!GO:0044267;cellular protein metabolic process;1.47120773251884e-39!GO:0033036;macromolecule localization;2.13206702151318e-39!GO:0015031;protein transport;3.38105425440628e-38!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.12065877286939e-37!GO:0006412;translation;1.38884455898511e-36!GO:0016071;mRNA metabolic process;6.27616180575609e-36!GO:0008104;protein localization;1.14352749622472e-35!GO:0045184;establishment of protein localization;1.93867955029179e-35!GO:0005840;ribosome;1.47145450195332e-34!GO:0046907;intracellular transport;3.75362122799039e-34!GO:0006996;organelle organization and biogenesis;1.97274315416081e-33!GO:0010467;gene expression;5.64966460797801e-33!GO:0009058;biosynthetic process;9.64649777797804e-33!GO:0043228;non-membrane-bound organelle;1.85174294471786e-32!GO:0043232;intracellular non-membrane-bound organelle;1.85174294471786e-32!GO:0009059;macromolecule biosynthetic process;3.75762158477236e-32!GO:0006259;DNA metabolic process;1.19145894869452e-31!GO:0006397;mRNA processing;4.52354658200447e-31!GO:0031967;organelle envelope;1.53866748255722e-30!GO:0008380;RNA splicing;1.83116896423047e-30!GO:0065003;macromolecular complex assembly;2.28416714875619e-30!GO:0003735;structural constituent of ribosome;3.02646926167028e-30!GO:0031975;envelope;3.16290083496165e-30!GO:0005829;cytosol;4.03827316780437e-30!GO:0000166;nucleotide binding;7.64180050755644e-29!GO:0022607;cellular component assembly;4.34350547318966e-28!GO:0006886;intracellular protein transport;7.20722874912806e-28!GO:0044249;cellular biosynthetic process;1.05406429917103e-27!GO:0044429;mitochondrial part;1.24794698330316e-27!GO:0033279;ribosomal subunit;2.60909725422961e-27!GO:0007049;cell cycle;1.04026560193397e-26!GO:0005783;endoplasmic reticulum;2.35055474624043e-26!GO:0012505;endomembrane system;6.0795591126676e-26!GO:0005654;nucleoplasm;4.07407152503669e-25!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.44135343388074e-24!GO:0016462;pyrophosphatase activity;6.41353214466105e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.00087874944676e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.44459046526939e-23!GO:0017111;nucleoside-triphosphatase activity;2.28197678171765e-23!GO:0003676;nucleic acid binding;6.61012854233673e-23!GO:0044432;endoplasmic reticulum part;9.16910463559271e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.13186808354779e-22!GO:0022402;cell cycle process;1.00211351774527e-21!GO:0051641;cellular localization;1.58912246351335e-21!GO:0051649;establishment of cellular localization;1.69774350736127e-21!GO:0005681;spliceosome;1.92455204178046e-21!GO:0000278;mitotic cell cycle;2.32127865676844e-20!GO:0017076;purine nucleotide binding;2.32726702905726e-20!GO:0005524;ATP binding;2.32726702905726e-20!GO:0048770;pigment granule;2.41326603547256e-20!GO:0042470;melanosome;2.41326603547256e-20!GO:0032553;ribonucleotide binding;6.34209858938657e-20!GO:0032555;purine ribonucleotide binding;6.34209858938657e-20!GO:0030554;adenyl nucleotide binding;7.69369266554057e-20!GO:0044451;nucleoplasm part;8.89119257681461e-20!GO:0032559;adenyl ribonucleotide binding;1.17481753539631e-19!GO:0006974;response to DNA damage stimulus;6.54594039108334e-19!GO:0006457;protein folding;4.40187447213278e-18!GO:0005794;Golgi apparatus;3.50058812634768e-17!GO:0005740;mitochondrial envelope;4.22772275067702e-17!GO:0016874;ligase activity;5.54051202725517e-17!GO:0044445;cytosolic part;1.60304725049736e-16!GO:0000087;M phase of mitotic cell cycle;1.69828519777357e-16!GO:0031966;mitochondrial membrane;1.87832437221116e-16!GO:0007067;mitosis;2.11474882884746e-16!GO:0019866;organelle inner membrane;4.0884585657517e-16!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.14093361218537e-16!GO:0005730;nucleolus;4.43161142854486e-16!GO:0022403;cell cycle phase;4.73706599397633e-16!GO:0016887;ATPase activity;5.57972912645164e-16!GO:0006119;oxidative phosphorylation;7.70982533551894e-16!GO:0006281;DNA repair;8.19439310459686e-16!GO:0042623;ATPase activity, coupled;9.48173066094972e-16!GO:0005694;chromosome;1.05611657579437e-15!GO:0016070;RNA metabolic process;1.21107587961523e-15!GO:0005789;endoplasmic reticulum membrane;2.34560906896552e-15!GO:0048193;Golgi vesicle transport;9.49569914226474e-15!GO:0043285;biopolymer catabolic process;1.80127050987233e-14!GO:0005635;nuclear envelope;3.22359544207667e-14!GO:0015934;large ribosomal subunit;4.25929012739034e-14!GO:0005743;mitochondrial inner membrane;5.1450397729618e-14!GO:0015935;small ribosomal subunit;6.18568611207243e-14!GO:0004386;helicase activity;6.85050483455277e-14!GO:0051301;cell division;7.60196159651864e-14!GO:0009719;response to endogenous stimulus;7.94306385088146e-14!GO:0031965;nuclear membrane;8.11897560206018e-14!GO:0051276;chromosome organization and biogenesis;1.14918625124991e-13!GO:0005793;ER-Golgi intermediate compartment;1.14918625124991e-13!GO:0000279;M phase;1.14918625124991e-13!GO:0000502;proteasome complex (sensu Eukaryota);1.40250030406981e-13!GO:0044427;chromosomal part;1.50491981318704e-13!GO:0022618;protein-RNA complex assembly;1.70889252151152e-13!GO:0008134;transcription factor binding;2.30157451574767e-13!GO:0044265;cellular macromolecule catabolic process;2.32987954813186e-13!GO:0008135;translation factor activity, nucleic acid binding;2.48490870310637e-13!GO:0051082;unfolded protein binding;3.02304392940362e-13!GO:0009057;macromolecule catabolic process;3.18096794559076e-13!GO:0044453;nuclear membrane part;3.4843961920721e-13!GO:0006260;DNA replication;4.70182444490201e-13!GO:0031980;mitochondrial lumen;5.05733766796511e-13!GO:0005759;mitochondrial matrix;5.05733766796511e-13!GO:0006605;protein targeting;5.24306540189046e-13!GO:0030163;protein catabolic process;7.47460734975199e-13!GO:0051603;proteolysis involved in cellular protein catabolic process;8.09119482742769e-13!GO:0019941;modification-dependent protein catabolic process;1.77681449557358e-12!GO:0043632;modification-dependent macromolecule catabolic process;1.77681449557358e-12!GO:0044257;cellular protein catabolic process;1.82000291125118e-12!GO:0006511;ubiquitin-dependent protein catabolic process;1.85607141725758e-12!GO:0044455;mitochondrial membrane part;2.35525984730388e-12!GO:0008026;ATP-dependent helicase activity;5.56513413212832e-12!GO:0006512;ubiquitin cycle;6.83442031755692e-12!GO:0016192;vesicle-mediated transport;7.00104955382614e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;7.05445880846288e-12!GO:0000375;RNA splicing, via transesterification reactions;7.05445880846288e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;7.05445880846288e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.67117764906875e-12!GO:0051186;cofactor metabolic process;1.53606445957881e-11!GO:0042254;ribosome biogenesis and assembly;2.48255153263519e-11!GO:0043412;biopolymer modification;4.08244686207179e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.07606736846296e-11!GO:0051726;regulation of cell cycle;1.05763835119334e-10!GO:0005788;endoplasmic reticulum lumen;1.06062686214628e-10!GO:0000074;regulation of progression through cell cycle;1.18824269083986e-10!GO:0006399;tRNA metabolic process;1.2099797610714e-10!GO:0016604;nuclear body;1.21495767137374e-10!GO:0006461;protein complex assembly;1.26225430333363e-10!GO:0005746;mitochondrial respiratory chain;1.30734888305992e-10!GO:0044248;cellular catabolic process;1.4312495554323e-10!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.46491691888603e-10!GO:0003743;translation initiation factor activity;1.75734966734705e-10!GO:0006913;nucleocytoplasmic transport;2.4266528360954e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;3.047572511312e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.78737071621097e-10!GO:0004812;aminoacyl-tRNA ligase activity;3.78737071621097e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.78737071621097e-10!GO:0051169;nuclear transport;5.25008936557908e-10!GO:0015630;microtubule cytoskeleton;5.4665016234784e-10!GO:0043038;amino acid activation;6.30286281392117e-10!GO:0006418;tRNA aminoacylation for protein translation;6.30286281392117e-10!GO:0043039;tRNA aminoacylation;6.30286281392117e-10!GO:0006323;DNA packaging;8.69146539648797e-10!GO:0005643;nuclear pore;9.6452006451882e-10!GO:0006464;protein modification process;1.57283172834582e-09!GO:0016787;hydrolase activity;1.95800829325055e-09!GO:0050136;NADH dehydrogenase (quinone) activity;2.1440744722339e-09!GO:0003954;NADH dehydrogenase activity;2.1440744722339e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.1440744722339e-09!GO:0016607;nuclear speck;2.45561506862878e-09!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.66039004690569e-09!GO:0008565;protein transporter activity;4.13530679650578e-09!GO:0003712;transcription cofactor activity;4.26404880066032e-09!GO:0006403;RNA localization;5.87749064095459e-09!GO:0006732;coenzyme metabolic process;7.03565168175413e-09!GO:0050657;nucleic acid transport;9.50205572896623e-09!GO:0051236;establishment of RNA localization;9.50205572896623e-09!GO:0050658;RNA transport;9.50205572896623e-09!GO:0009259;ribonucleotide metabolic process;1.14442138204712e-08!GO:0006888;ER to Golgi vesicle-mediated transport;1.36972584243568e-08!GO:0006413;translational initiation;1.39277202831261e-08!GO:0046930;pore complex;2.19583730260993e-08!GO:0006446;regulation of translational initiation;3.1062902688618e-08!GO:0042775;organelle ATP synthesis coupled electron transport;3.37506418827114e-08!GO:0042773;ATP synthesis coupled electron transport;3.37506418827114e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.81921873569947e-08!GO:0065002;intracellular protein transport across a membrane;3.87942160280675e-08!GO:0030964;NADH dehydrogenase complex (quinone);4.21721274922295e-08!GO:0045271;respiratory chain complex I;4.21721274922295e-08!GO:0005747;mitochondrial respiratory chain complex I;4.21721274922295e-08!GO:0044431;Golgi apparatus part;4.25488210491053e-08!GO:0043566;structure-specific DNA binding;4.34573629817366e-08!GO:0048523;negative regulation of cellular process;4.76805284786551e-08!GO:0008639;small protein conjugating enzyme activity;4.76805284786551e-08!GO:0004842;ubiquitin-protein ligase activity;5.35328894069624e-08!GO:0006163;purine nucleotide metabolic process;5.37600532095087e-08!GO:0005761;mitochondrial ribosome;5.37600532095087e-08!GO:0000313;organellar ribosome;5.37600532095087e-08!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.57107508158894e-08!GO:0050794;regulation of cellular process;8.88819021124106e-08!GO:0009150;purine ribonucleotide metabolic process;9.30698603725218e-08!GO:0009260;ribonucleotide biosynthetic process;9.5095022784609e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.96726447272322e-08!GO:0005819;spindle;1.02591912787975e-07!GO:0065004;protein-DNA complex assembly;1.19598634802944e-07!GO:0030120;vesicle coat;1.22811774673715e-07!GO:0030662;coated vesicle membrane;1.22811774673715e-07!GO:0006164;purine nucleotide biosynthetic process;1.51480755066823e-07!GO:0043687;post-translational protein modification;1.59447167880335e-07!GO:0006333;chromatin assembly or disassembly;1.6229452040424e-07!GO:0019787;small conjugating protein ligase activity;1.75917009415003e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.86706680830119e-07!GO:0048475;coated membrane;1.88963954416367e-07!GO:0030117;membrane coat;1.88963954416367e-07!GO:0005773;vacuole;2.16873000753929e-07!GO:0051028;mRNA transport;2.29736887287565e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.4743986381882e-07!GO:0009055;electron carrier activity;2.67376268148377e-07!GO:0000785;chromatin;3.90817465660219e-07!GO:0005813;centrosome;4.68075868854184e-07!GO:0003697;single-stranded DNA binding;5.06234185243616e-07!GO:0015986;ATP synthesis coupled proton transport;5.17794144775699e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;5.17794144775699e-07!GO:0017038;protein import;5.95169936676527e-07!GO:0009060;aerobic respiration;6.11692344357856e-07!GO:0006364;rRNA processing;6.31271103677672e-07!GO:0031988;membrane-bound vesicle;6.93555973785115e-07!GO:0005815;microtubule organizing center;7.44807631551562e-07!GO:0012501;programmed cell death;7.97789656417034e-07!GO:0016881;acid-amino acid ligase activity;1.0397886301158e-06!GO:0016023;cytoplasmic membrane-bound vesicle;1.09483088005942e-06!GO:0005768;endosome;1.16793251480349e-06!GO:0009056;catabolic process;1.1987893652569e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.23578382503804e-06!GO:0006915;apoptosis;1.23632101293726e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.23876574917491e-06!GO:0048519;negative regulation of biological process;1.32217294388376e-06!GO:0007051;spindle organization and biogenesis;1.36163396405121e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.41261305324909e-06!GO:0016072;rRNA metabolic process;1.43275049121361e-06!GO:0045333;cellular respiration;1.46616327414742e-06!GO:0003724;RNA helicase activity;1.48600055790788e-06!GO:0009141;nucleoside triphosphate metabolic process;1.6735528204149e-06!GO:0000323;lytic vacuole;1.6735528204149e-06!GO:0005764;lysosome;1.6735528204149e-06!GO:0046034;ATP metabolic process;1.72390845095277e-06!GO:0006099;tricarboxylic acid cycle;1.83177888071665e-06!GO:0046356;acetyl-CoA catabolic process;1.83177888071665e-06!GO:0051187;cofactor catabolic process;1.94997518521184e-06!GO:0016740;transferase activity;2.01224687051837e-06!GO:0006261;DNA-dependent DNA replication;2.01700000734302e-06!GO:0007010;cytoskeleton organization and biogenesis;2.28553776165085e-06!GO:0016568;chromatin modification;2.33097742068406e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.40793071122201e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.40793071122201e-06!GO:0019829;cation-transporting ATPase activity;2.64868684082839e-06!GO:0000139;Golgi membrane;2.75143416444203e-06!GO:0006366;transcription from RNA polymerase II promoter;2.77204727946575e-06!GO:0008219;cell death;3.08167312410091e-06!GO:0016265;death;3.08167312410091e-06!GO:0009109;coenzyme catabolic process;3.26624710179313e-06!GO:0005798;Golgi-associated vesicle;3.85508946680578e-06!GO:0000775;chromosome, pericentric region;4.01369589538727e-06!GO:0031982;vesicle;4.27359706517938e-06!GO:0008094;DNA-dependent ATPase activity;4.47933678708221e-06!GO:0006334;nucleosome assembly;4.70451137824591e-06!GO:0051789;response to protein stimulus;5.64044325854988e-06!GO:0006986;response to unfolded protein;5.64044325854988e-06!GO:0005667;transcription factor complex;5.78650536363314e-06!GO:0009142;nucleoside triphosphate biosynthetic process;6.43767657312147e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.43767657312147e-06!GO:0006084;acetyl-CoA metabolic process;6.68183462305348e-06!GO:0031410;cytoplasmic vesicle;6.68183462305348e-06!GO:0015078;hydrogen ion transmembrane transporter activity;6.81848214234328e-06!GO:0031497;chromatin assembly;7.10193599654335e-06!GO:0030532;small nuclear ribonucleoprotein complex;7.54450798128944e-06!GO:0006754;ATP biosynthetic process;7.7767133055682e-06!GO:0006753;nucleoside phosphate metabolic process;7.7767133055682e-06!GO:0051188;cofactor biosynthetic process;8.19743619172485e-06!GO:0008654;phospholipid biosynthetic process;8.3393476849214e-06!GO:0043623;cellular protein complex assembly;9.01251855883018e-06!GO:0031324;negative regulation of cellular metabolic process;1.06850548654913e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.07208361843609e-05!GO:0009117;nucleotide metabolic process;1.27954060494963e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.29566787620128e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.29566787620128e-05!GO:0016469;proton-transporting two-sector ATPase complex;1.32584803913866e-05!GO:0051170;nuclear import;1.51466182191714e-05!GO:0006613;cotranslational protein targeting to membrane;1.72426124193434e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.91662848300927e-05!GO:0006606;protein import into nucleus;2.12677042037045e-05!GO:0016779;nucleotidyltransferase activity;2.19493494807883e-05!GO:0051329;interphase of mitotic cell cycle;2.31035464253963e-05!GO:0000075;cell cycle checkpoint;2.39773394989897e-05!GO:0019899;enzyme binding;2.59604681535513e-05!GO:0006752;group transfer coenzyme metabolic process;2.67270026074368e-05!GO:0044440;endosomal part;2.68261735392908e-05!GO:0010008;endosome membrane;2.68261735392908e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.75984181313415e-05!GO:0051325;interphase;2.98442139352638e-05!GO:0030867;rough endoplasmic reticulum membrane;3.1037606751814e-05!GO:0045786;negative regulation of progression through cell cycle;3.30396612954564e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.46601868396844e-05!GO:0000151;ubiquitin ligase complex;3.46792095253063e-05!GO:0016853;isomerase activity;3.53490809406869e-05!GO:0000245;spliceosome assembly;3.92920926128477e-05!GO:0005839;proteasome core complex (sensu Eukaryota);4.30844135370114e-05!GO:0051246;regulation of protein metabolic process;4.41736922345222e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;4.49106282766662e-05!GO:0030036;actin cytoskeleton organization and biogenesis;4.56832905128662e-05!GO:0045259;proton-transporting ATP synthase complex;5.95586257606042e-05!GO:0050789;regulation of biological process;6.42095863630537e-05!GO:0009892;negative regulation of metabolic process;6.76204427172485e-05!GO:0003690;double-stranded DNA binding;6.8023129730728e-05!GO:0003924;GTPase activity;6.83231624107266e-05!GO:0033116;ER-Golgi intermediate compartment membrane;7.09361308088485e-05!GO:0031252;leading edge;7.10145101401265e-05!GO:0016859;cis-trans isomerase activity;7.21469187085037e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.31849207882894e-05!GO:0016564;transcription repressor activity;7.90937970048605e-05!GO:0003714;transcription corepressor activity;8.95053138959986e-05!GO:0030133;transport vesicle;9.02531809198182e-05!GO:0003678;DNA helicase activity;9.03502750589798e-05!GO:0016491;oxidoreductase activity;9.11952999332926e-05!GO:0016363;nuclear matrix;9.19880953737999e-05!GO:0006793;phosphorus metabolic process;9.19880953737999e-05!GO:0006796;phosphate metabolic process;9.19880953737999e-05!GO:0032446;protein modification by small protein conjugation;9.88695778863172e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000104115668167896!GO:0005905;coated pit;0.000111442051491577!GO:0008186;RNA-dependent ATPase activity;0.000117010323639608!GO:0009108;coenzyme biosynthetic process;0.000118180134701559!GO:0016049;cell growth;0.000130648216049806!GO:0003713;transcription coactivator activity;0.000138565447645571!GO:0008361;regulation of cell size;0.000138565447645571!GO:0016567;protein ubiquitination;0.000138728735414641!GO:0004576;oligosaccharyl transferase activity;0.000138728735414641!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000138938801244182!GO:0005874;microtubule;0.000139764925424997!GO:0005770;late endosome;0.000149240628960835!GO:0016310;phosphorylation;0.000149771859687728!GO:0051168;nuclear export;0.000172407508261823!GO:0004298;threonine endopeptidase activity;0.000176563043071604!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000192629922794964!GO:0005657;replication fork;0.000202076911815623!GO:0019843;rRNA binding;0.00020671415977971!GO:0043067;regulation of programmed cell death;0.000213222929188333!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000214587956226983!GO:0015399;primary active transmembrane transporter activity;0.000214587956226983!GO:0042981;regulation of apoptosis;0.000221412906039761!GO:0006916;anti-apoptosis;0.000227284561374339!GO:0008250;oligosaccharyl transferase complex;0.00023391414815922!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000241335125225293!GO:0003684;damaged DNA binding;0.0002413507505127!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0002413507505127!GO:0006302;double-strand break repair;0.000253121824907216!GO:0006612;protein targeting to membrane;0.000254431090430468!GO:0006310;DNA recombination;0.00026059090754014!GO:0043069;negative regulation of programmed cell death;0.000267336573110234!GO:0000776;kinetochore;0.000271519039097947!GO:0044262;cellular carbohydrate metabolic process;0.000297758839417869!GO:0051427;hormone receptor binding;0.000320368885347606!GO:0016563;transcription activator activity;0.000339283039291206!GO:0015980;energy derivation by oxidation of organic compounds;0.000346910408120295!GO:0004004;ATP-dependent RNA helicase activity;0.000353901990891791!GO:0008092;cytoskeletal protein binding;0.000373005265642855!GO:0046474;glycerophospholipid biosynthetic process;0.000374815348473499!GO:0046489;phosphoinositide biosynthetic process;0.000387808599504566!GO:0001558;regulation of cell growth;0.000429708628950948!GO:0031968;organelle outer membrane;0.000442671628885093!GO:0045454;cell redox homeostasis;0.000443750040221032!GO:0007052;mitotic spindle organization and biogenesis;0.000460265247123398!GO:0000059;protein import into nucleus, docking;0.000465619039663353!GO:0030029;actin filament-based process;0.00046877416736423!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000478170254674738!GO:0043066;negative regulation of apoptosis;0.000492524314552433!GO:0019867;outer membrane;0.000534441324322929!GO:0005048;signal sequence binding;0.000569692093922173!GO:0051252;regulation of RNA metabolic process;0.000579695230310092!GO:0035257;nuclear hormone receptor binding;0.000604694932132605!GO:0043284;biopolymer biosynthetic process;0.000609564912506252!GO:0030134;ER to Golgi transport vesicle;0.000612569652286293!GO:0043021;ribonucleoprotein binding;0.000619851962203021!GO:0006414;translational elongation;0.000628398039634812!GO:0007059;chromosome segregation;0.000684147144157037!GO:0005769;early endosome;0.000685295532503125!GO:0016481;negative regulation of transcription;0.000698016379506839!GO:0030663;COPI coated vesicle membrane;0.000713978697181983!GO:0030126;COPI vesicle coat;0.000713978697181983!GO:0005791;rough endoplasmic reticulum;0.000751999894911007!GO:0003729;mRNA binding;0.000753093742109644!GO:0018196;peptidyl-asparagine modification;0.000804218980914701!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.000804218980914701!GO:0005885;Arp2/3 protein complex;0.000965446499055246!GO:0031124;mRNA 3'-end processing;0.00103559336065581!GO:0003682;chromatin binding;0.00109821865064301!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00121693193312022!GO:0004177;aminopeptidase activity;0.00122458343556951!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00133372985005044!GO:0043492;ATPase activity, coupled to movement of substances;0.00138671108019304!GO:0007093;mitotic cell cycle checkpoint;0.00146991135278905!GO:0019222;regulation of metabolic process;0.00148302292515607!GO:0006091;generation of precursor metabolites and energy;0.00152349500766095!GO:0051052;regulation of DNA metabolic process;0.00153557348733628!GO:0030137;COPI-coated vesicle;0.00163007761746967!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00173572482031513!GO:0030127;COPII vesicle coat;0.00179528208189829!GO:0012507;ER to Golgi transport vesicle membrane;0.00179528208189829!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00194998988529459!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00196874687633283!GO:0006891;intra-Golgi vesicle-mediated transport;0.00196874687633283!GO:0048471;perinuclear region of cytoplasm;0.00202621614305128!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00203941428236758!GO:0004527;exonuclease activity;0.0020734011819422!GO:0030176;integral to endoplasmic reticulum membrane;0.00209739714141989!GO:0005637;nuclear inner membrane;0.00213252431749111!GO:0016197;endosome transport;0.00213252431749111!GO:0046467;membrane lipid biosynthetic process;0.00215652582883015!GO:0015631;tubulin binding;0.00220016213670513!GO:0051920;peroxiredoxin activity;0.00224340136143255!GO:0006402;mRNA catabolic process;0.00224919900382699!GO:0008047;enzyme activator activity;0.00226533049836936!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00242688423109116!GO:0003899;DNA-directed RNA polymerase activity;0.00243204085749841!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00243561521283054!GO:0006950;response to stress;0.00246652900882437!GO:0005762;mitochondrial large ribosomal subunit;0.00256240548848632!GO:0000315;organellar large ribosomal subunit;0.00256240548848632!GO:0007040;lysosome organization and biogenesis;0.00260760052226133!GO:0008610;lipid biosynthetic process;0.00262501761471256!GO:0007088;regulation of mitosis;0.00273542080502313!GO:0004003;ATP-dependent DNA helicase activity;0.00273950181662817!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00274165467183299!GO:0000922;spindle pole;0.00274165467183299!GO:0008022;protein C-terminus binding;0.00277717669030354!GO:0019798;procollagen-proline dioxygenase activity;0.00282240056491131!GO:0006509;membrane protein ectodomain proteolysis;0.00285076519040597!GO:0033619;membrane protein proteolysis;0.00285076519040597!GO:0007005;mitochondrion organization and biogenesis;0.00288518940801396!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00288518940801396!GO:0000910;cytokinesis;0.00288518940801396!GO:0009165;nucleotide biosynthetic process;0.00332495958365654!GO:0030132;clathrin coat of coated pit;0.00344381850540718!GO:0006497;protein amino acid lipidation;0.00348838692098696!GO:0006289;nucleotide-excision repair;0.00361244576295129!GO:0044452;nucleolar part;0.00361244576295129!GO:0005876;spindle microtubule;0.00364241077324547!GO:0048522;positive regulation of cellular process;0.00366204090472791!GO:0007033;vacuole organization and biogenesis;0.00374060927062024!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00383049369598024!GO:0030658;transport vesicle membrane;0.00387122931779641!GO:0042802;identical protein binding;0.00387122931779641!GO:0005741;mitochondrial outer membrane;0.00390235287127542!GO:0065007;biological regulation;0.00407463609114009!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00407930043831216!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00413692500053387!GO:0006650;glycerophospholipid metabolic process;0.0041961986958692!GO:0007017;microtubule-based process;0.00427229029132356!GO:0006506;GPI anchor biosynthetic process;0.00462952500632832!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00464598611783598!GO:0000786;nucleosome;0.00488522441511351!GO:0031543;peptidyl-proline dioxygenase activity;0.00492269506541471!GO:0006505;GPI anchor metabolic process;0.00514080030116311!GO:0008033;tRNA processing;0.00530460438939465!GO:0006892;post-Golgi vesicle-mediated transport;0.00539814572742334!GO:0004674;protein serine/threonine kinase activity;0.00545966864128679!GO:0048500;signal recognition particle;0.00556341190585096!GO:0065009;regulation of a molecular function;0.00568704958999709!GO:0017166;vinculin binding;0.00568704958999709!GO:0046519;sphingoid metabolic process;0.00583639054633418!GO:0030118;clathrin coat;0.00598295929495993!GO:0006378;mRNA polyadenylation;0.00622333639263157!GO:0007050;cell cycle arrest;0.00648761827830008!GO:0050662;coenzyme binding;0.0066427274138027!GO:0032508;DNA duplex unwinding;0.00684981907206126!GO:0032392;DNA geometric change;0.00684981907206126!GO:0031123;RNA 3'-end processing;0.00700623441722388!GO:0000082;G1/S transition of mitotic cell cycle;0.00725680716208944!GO:0016126;sterol biosynthetic process;0.00767579373909288!GO:0001726;ruffle;0.00777872201575426!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0078345052934808!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0078345052934808!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0078345052934808!GO:0030521;androgen receptor signaling pathway;0.00796124598231789!GO:0005525;GTP binding;0.0079741662474357!GO:0000049;tRNA binding;0.00814193397185035!GO:0007243;protein kinase cascade;0.00850556133681059!GO:0030660;Golgi-associated vesicle membrane;0.00860130593504985!GO:0042158;lipoprotein biosynthetic process;0.00882181049841978!GO:0008139;nuclear localization sequence binding;0.00883477838233691!GO:0051539;4 iron, 4 sulfur cluster binding;0.00888152553518556!GO:0032200;telomere organization and biogenesis;0.00891104476949637!GO:0000723;telomere maintenance;0.00891104476949637!GO:0031418;L-ascorbic acid binding;0.00910368994446544!GO:0006818;hydrogen transport;0.00926398179565678!GO:0003923;GPI-anchor transamidase activity;0.00933415976799789!GO:0016255;attachment of GPI anchor to protein;0.00933415976799789!GO:0042765;GPI-anchor transamidase complex;0.00933415976799789!GO:0008312;7S RNA binding;0.00966608139090082!GO:0030384;phosphoinositide metabolic process;0.00990054339902116!GO:0006405;RNA export from nucleus;0.00991294796167615!GO:0005684;U2-dependent spliceosome;0.0100324698188487!GO:0015992;proton transport;0.0100871456032716!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0103306648103028!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0103306648103028!GO:0006401;RNA catabolic process;0.0103962078162711!GO:0003746;translation elongation factor activity;0.0108281389720749!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0108466713546087!GO:0045047;protein targeting to ER;0.0108466713546087!GO:0005774;vacuolar membrane;0.0111378169144471!GO:0006268;DNA unwinding during replication;0.0111568287733585!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0111568287733585!GO:0043488;regulation of mRNA stability;0.0117302140970549!GO:0043487;regulation of RNA stability;0.0117302140970549!GO:0003711;transcription elongation regulator activity;0.0123421473979629!GO:0030659;cytoplasmic vesicle membrane;0.012503205127596!GO:0006383;transcription from RNA polymerase III promoter;0.0126271083616682!GO:0030032;lamellipodium biogenesis;0.0131216940751483!GO:0031072;heat shock protein binding;0.0133106947974047!GO:0006672;ceramide metabolic process;0.0134865513149385!GO:0005832;chaperonin-containing T-complex;0.0139549219616032!GO:0006275;regulation of DNA replication;0.0139735928737591!GO:0001527;microfibril;0.0145984670313347!GO:0009112;nucleobase metabolic process;0.0148767589614277!GO:0006984;ER-nuclear signaling pathway;0.015138139976276!GO:0035258;steroid hormone receptor binding;0.0152832179262692!GO:0003756;protein disulfide isomerase activity;0.0156122658594964!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0156122658594964!GO:0019752;carboxylic acid metabolic process;0.0161295055541471!GO:0044420;extracellular matrix part;0.0166438913836428!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0173911285909231!GO:0046483;heterocycle metabolic process;0.0174266108202296!GO:0007041;lysosomal transport;0.0175843309173227!GO:0031625;ubiquitin protein ligase binding;0.0175843309173227!GO:0016044;membrane organization and biogenesis;0.0176184649636933!GO:0005862;muscle thin filament tropomyosin;0.0177240391627372!GO:0030041;actin filament polymerization;0.018232726435052!GO:0040008;regulation of growth;0.0183716462700515!GO:0030433;ER-associated protein catabolic process;0.019371782209957!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.019371782209957!GO:0006284;base-excision repair;0.019417457310934!GO:0000030;mannosyltransferase activity;0.0194238391170841!GO:0016408;C-acyltransferase activity;0.0194454187018406!GO:0006082;organic acid metabolic process;0.0194968973752454!GO:0005096;GTPase activator activity;0.0196087363706474!GO:0051271;negative regulation of cell motility;0.0196351117422779!GO:0004518;nuclease activity;0.0197028344171433!GO:0044433;cytoplasmic vesicle part;0.0197565346126355!GO:0031529;ruffle organization and biogenesis;0.0198617539924851!GO:0007034;vacuolar transport;0.0203154441026043!GO:0000781;chromosome, telomeric region;0.0207115407176535!GO:0012506;vesicle membrane;0.0215663584118949!GO:0000070;mitotic sister chromatid segregation;0.0219948064286337!GO:0007030;Golgi organization and biogenesis;0.0223817251639846!GO:0000314;organellar small ribosomal subunit;0.0229998360418803!GO:0005763;mitochondrial small ribosomal subunit;0.0229998360418803!GO:0032561;guanyl ribonucleotide binding;0.0232178122527404!GO:0019001;guanyl nucleotide binding;0.0232178122527404!GO:0000287;magnesium ion binding;0.0232432921707676!GO:0000819;sister chromatid segregation;0.0232432921707676!GO:0031901;early endosome membrane;0.0233785893125245!GO:0000339;RNA cap binding;0.0234243574689325!GO:0006352;transcription initiation;0.0235653910361341!GO:0016584;nucleosome positioning;0.0241830417279579!GO:0030027;lamellipodium;0.0243913430797264!GO:0044437;vacuolar part;0.0251637077373104!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0256417361846967!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0256637402689266!GO:0008180;signalosome;0.0260803372607981!GO:0022408;negative regulation of cell-cell adhesion;0.0261952026988055!GO:0006541;glutamine metabolic process;0.0265988038637333!GO:0030119;AP-type membrane coat adaptor complex;0.0266266149391663!GO:0051287;NAD binding;0.0266524645104277!GO:0030149;sphingolipid catabolic process;0.0271440272249417!GO:0051128;regulation of cellular component organization and biogenesis;0.0272408665682185!GO:0022890;inorganic cation transmembrane transporter activity;0.0282097639043753!GO:0043022;ribosome binding;0.0286469241031765!GO:0031323;regulation of cellular metabolic process;0.0291988337464681!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0294006242398171!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0294006242398171!GO:0045045;secretory pathway;0.0295752501636823!GO:0005869;dynactin complex;0.0306884746152043!GO:0008484;sulfuric ester hydrolase activity;0.0307046875211527!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.030962629603118!GO:0030131;clathrin adaptor complex;0.0315826860450336!GO:0003779;actin binding;0.031959342295806!GO:0006379;mRNA cleavage;0.0321666956394979!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0322077212479709!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0326302727548217!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0326302727548217!GO:0051540;metal cluster binding;0.0329540637146399!GO:0051536;iron-sulfur cluster binding;0.0329540637146399!GO:0030518;steroid hormone receptor signaling pathway;0.032961289145554!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0331831668437174!GO:0006376;mRNA splice site selection;0.0331831668437174!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0331831668437174!GO:0030145;manganese ion binding;0.0336750146608985!GO:0004563;beta-N-acetylhexosaminidase activity;0.0338210316639338!GO:0000792;heterochromatin;0.0338894664673034!GO:0040029;regulation of gene expression, epigenetic;0.0344376211263471!GO:0050790;regulation of catalytic activity;0.034556253487667!GO:0005765;lysosomal membrane;0.0345667750235929!GO:0008154;actin polymerization and/or depolymerization;0.0346081723530845!GO:0006520;amino acid metabolic process;0.0346681544191716!GO:0006611;protein export from nucleus;0.0350491068984455!GO:0005784;translocon complex;0.0350491068984455!GO:0006144;purine base metabolic process;0.0355388069371797!GO:0006626;protein targeting to mitochondrion;0.0356521617591412!GO:0035267;NuA4 histone acetyltransferase complex;0.0362951384601474!GO:0007160;cell-matrix adhesion;0.0365386657014981!GO:0033559;unsaturated fatty acid metabolic process;0.0367431518952227!GO:0006636;unsaturated fatty acid biosynthetic process;0.0367431518952227!GO:0006595;polyamine metabolic process;0.0368231520565387!GO:0007346;regulation of progression through mitotic cell cycle;0.0370097746918557!GO:0016741;transferase activity, transferring one-carbon groups;0.0376358810857665!GO:0005856;cytoskeleton;0.0376358810857665!GO:0031902;late endosome membrane;0.0376358810857665!GO:0006643;membrane lipid metabolic process;0.0388862247532263!GO:0043681;protein import into mitochondrion;0.0388862247532263!GO:0048037;cofactor binding;0.0388902884399211!GO:0004287;prolyl oligopeptidase activity;0.0393068808949325!GO:0048487;beta-tubulin binding;0.0400027287758298!GO:0050681;androgen receptor binding;0.0400027287758298!GO:0005581;collagen;0.0402042016164586!GO:0008168;methyltransferase activity;0.0405922614434742!GO:0000152;nuclear ubiquitin ligase complex;0.0410841687897146!GO:0031589;cell-substrate adhesion;0.0411018413749896!GO:0006607;NLS-bearing substrate import into nucleus;0.0411740517301565!GO:0045892;negative regulation of transcription, DNA-dependent;0.0421364471385178!GO:0043631;RNA polyadenylation;0.0430588696451862!GO:0007162;negative regulation of cell adhesion;0.0433501543969957!GO:0008017;microtubule binding;0.0433501543969957!GO:0031570;DNA integrity checkpoint;0.0433501543969957!GO:0006740;NADPH regeneration;0.0433501543969957!GO:0006098;pentose-phosphate shunt;0.0433501543969957!GO:0043433;negative regulation of transcription factor activity;0.0436878556833001!GO:0007004;telomere maintenance via telomerase;0.043705486200147!GO:0001952;regulation of cell-matrix adhesion;0.043705486200147!GO:0030833;regulation of actin filament polymerization;0.0437333345751792!GO:0040013;negative regulation of locomotion;0.0441309857900611!GO:0000118;histone deacetylase complex;0.0442306568159144!GO:0004228;gelatinase A activity;0.0446813070023646!GO:0001955;blood vessel maturation;0.0446813070023646!GO:0009225;nucleotide-sugar metabolic process;0.0452010688107627!GO:0016251;general RNA polymerase II transcription factor activity;0.0459056540708595!GO:0000209;protein polyubiquitination;0.0459781314765151!GO:0006007;glucose catabolic process;0.0466667039256316!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0472025810191214!GO:0006897;endocytosis;0.0479147461652685!GO:0010324;membrane invagination;0.0479147461652685!GO:0045792;negative regulation of cell size;0.0480599033030033!GO:0030125;clathrin vesicle coat;0.0488706762924986!GO:0030665;clathrin coated vesicle membrane;0.0488706762924986!GO:0006695;cholesterol biosynthetic process;0.0490124242833776!GO:0030984;kininogen binding;0.0498884914892192!GO:0004213;cathepsin B activity;0.0498884914892192 | |||
|sample_id=14308 | |||
|sample_note= | |||
|sample_sex=M | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=HBP1_HMGB_SSRP1_UBTF:2.02362732466;NKX3-1:1.9661245678;EN1,2:1.80839746442;NKX3-2:1.74534668393;XBP1:1.72324107205;ALX4:1.72284306149;ZNF384:1.51784909382;KLF4:1.47514639421;GZF1:1.40902987494;HOX{A5,B5}:1.39868630168;HSF1,2:1.3942777101;TEAD1:1.36861309222;UFEwm:1.33913046235;NKX2-2,8:1.31891389118;ESR1:1.23104369248;ZNF238:1.22793343013;GFI1:1.13294261199;MYBL2:1.1205314549;RXRA_VDR{dimer}:1.06425495399;XCPE1{core}:1.05203863335;TOPORS:0.999177628055;SOX17:0.998983947446;HMGA1,2:0.954157060886;HIF1A:0.930041852333;HES1:0.909798576082;FOXL1:0.906768889218;TFDP1:0.872033415321;RXR{A,B,G}:0.867642373277;SRF:0.836552542399;GTF2A1,2:0.813157272724;GFI1B:0.812700077096;GTF2I:0.810083041659;GATA4:0.793829972739;E2F1..5:0.777442212533;EVI1:0.748048104083;MYB:0.746911339422;MZF1:0.741711081127;NR3C1:0.71461153537;MTE{core}:0.680679554053;AHR_ARNT_ARNT2:0.669194273153;TAL1_TCF{3,4,12}:0.652321327252;GCM1,2:0.618382603912;PRDM1:0.608906406772;TLX1..3_NFIC{dimer}:0.599185395707;ZIC1..3:0.597470668575;ELK1,4_GABP{A,B1}:0.574370916651;TP53:0.568744414169;GLI1..3:0.564344975473;NANOG{mouse}:0.494431311734;PAX8:0.474956308256;NFE2L1:0.470871899024;PAX3,7:0.450595227601;HOX{A4,D4}:0.430725485923;AIRE:0.426657204832;NRF1:0.417882293273;MAFB:0.393104128909;HMX1:0.386270569501;ZBTB6:0.383751327609;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.382749094737;ZNF143:0.366868628292;NFY{A,B,C}:0.361982512709;POU1F1:0.360435767517;STAT1,3:0.354637151321;BACH2:0.334077272922;TFAP2{A,C}:0.328821874319;SPZ1:0.328781090355;EBF1:0.327822796639;TFAP4:0.319659499655;MAZ:0.303607770804;SP1:0.299869020357;POU5F1:0.296517764709;MED-1{core}:0.279903130034;IKZF1:0.277484884259;FOS_FOS{B,L1}_JUN{B,D}:0.275311051272;YY1:0.266193558428;RFX1:0.254145779922;NFATC1..3:0.252302066782;DBP:0.247894930614;TFAP2B:0.217471502079;HLF:0.185346376955;TBP:0.147369271173;ALX1:0.140848743187;NFE2L2:0.135219298877;ATF6:0.126842559864;TEF:0.116669564676;CREB1:0.0557420847171;BPTF:0.0503056472259;NFE2:0.0411557305982;HOX{A6,A7,B6,B7}:0.0177366359447;EP300:0.0108387867238;ELF1,2,4:0.00431758096949;PAX1,9:-0.0172402110308;LEF1_TCF7_TCF7L1,2:-0.0302214847326;CRX:-0.0329504143859;MYFfamily:-0.0363117211436;SMAD1..7,9:-0.0391308410321;NKX2-1,4:-0.0399228854232;NHLH1,2:-0.0506505925919;CEBPA,B_DDIT3:-0.0564720621018;NR1H4:-0.0572369867845;CDC5L:-0.0584765939435;POU3F1..4:-0.0668810365765;HIC1:-0.0784496087156;SOX5:-0.0828434575045;ARID5B:-0.0834839698558;FOSL2:-0.0890007093172;ZNF148:-0.101572399669;ZNF423:-0.103910834868;PAX5:-0.117028808392;FOXP1:-0.118503981554;ZFP161:-0.125683889373;HAND1,2:-0.15353736581;EGR1..3:-0.15977062151;LHX3,4:-0.16531335706;FOXN1:-0.174965192989;TLX2:-0.195036732907;RREB1:-0.226547037037;FOXD3:-0.226909647476;ZBTB16:-0.233776932588;FOX{I1,J2}:-0.244554970089;PATZ1:-0.245253046259;TFCP2:-0.24532213002;RUNX1..3:-0.261630972128;PRRX1,2:-0.261715619116;IRF1,2:-0.268640099117;PPARG:-0.287644817515;bHLH_family:-0.288432999056;PAX2:-0.303710783935;AR:-0.317811863586;ATF5_CREB3:-0.318737061683;HNF1A:-0.319960536467;MEF2{A,B,C,D}:-0.352466243085;SREBF1,2:-0.368367894785;PDX1:-0.37618975982;SOX2:-0.386311655052;SOX{8,9,10}:-0.389962269122;SPI1:-0.393015089114;NFIX:-0.400286555701;TBX4,5:-0.427475583597;MTF1:-0.445628595836;NKX2-3_NKX2-5:-0.456375036966;HOXA9_MEIS1:-0.458343341261;SPIB:-0.471296769813;HNF4A_NR2F1,2:-0.475805807079;FOX{D1,D2}:-0.480009140526;NFIL3:-0.482078861139;ETS1,2:-0.486288918108;ADNP_IRX_SIX_ZHX:-0.516270402965;DMAP1_NCOR{1,2}_SMARC:-0.516541893452;ONECUT1,2:-0.528877310986;NANOG:-0.539772209238;NKX6-1,2:-0.54331693364;TGIF1:-0.545005301037;ATF4:-0.55031906081;STAT2,4,6:-0.552401473258;FOXO1,3,4:-0.555260087792;POU2F1..3:-0.567480699984;NFKB1_REL_RELA:-0.600380264071;STAT5{A,B}:-0.654951336728;POU6F1:-0.686290244923;IRF7:-0.721798645817;RBPJ:-0.756462156919;RFX2..5_RFXANK_RFXAP:-0.777031255016;REST:-0.796055974168;OCT4_SOX2{dimer}:-0.815820119046;BREu{core}:-0.822342151397;JUN:-0.824075831375;CUX2:-0.889581867269;PITX1..3:-0.890513359848;T:-0.902300016273;ATF2:-0.916973595677;NR6A1:-0.918418060265;PAX4:-0.920806036823;CDX1,2,4:-0.936754123136;FOXA2:-0.939659313094;GATA6:-0.989176987122;SNAI1..3:-0.999106471772;PAX6:-1.00368550548;FOXM1:-1.02095524466;PBX1:-1.03242824218;NR5A1,2:-1.07351049232;FOXQ1:-1.12329779589;ZEB1:-1.21407523771;FOXP3:-1.25878871319;VSX1,2:-1.3091163757;LMO2:-1.3263275507;MYOD1:-1.37374944805;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.51998164018;IKZF2:-1.54113233667;ESRRA:-1.64139519787;FOX{F1,F2,J1}:-1.69920757298;RORA:-2.1544203685 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:14308-155C6;search_select_hide=table117:FF:14308-155C6 | |||
}} | }} |
Latest revision as of 19:06, 4 June 2020
Name: | Fibroblast - skin dystrophia myotonica, donor3 (nuclear fraction) |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12399 |
Sample type: | fractionations and perturbations |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12399
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12399
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0988 |
10 | 10 | 0.63 |
100 | 100 | 0.895 |
101 | 101 | 0.193 |
102 | 102 | 0.398 |
103 | 103 | 0.136 |
104 | 104 | 0.663 |
105 | 105 | 0.437 |
106 | 106 | 0.0238 |
107 | 107 | 0.843 |
108 | 108 | 0.963 |
109 | 109 | 0.147 |
11 | 11 | 0.259 |
110 | 110 | 0.714 |
111 | 111 | 0.0678 |
112 | 112 | 0.697 |
113 | 113 | 0.0141 |
114 | 114 | 0.111 |
115 | 115 | 0.0819 |
116 | 116 | 0.821 |
117 | 117 | 0.504 |
118 | 118 | 0.589 |
119 | 119 | 0.105 |
12 | 12 | 0.812 |
120 | 120 | 0.999 |
121 | 121 | 0.555 |
122 | 122 | 0.278 |
123 | 123 | 0.00762 |
124 | 124 | 0.099 |
125 | 125 | 0.788 |
126 | 126 | 0.234 |
127 | 127 | 0.336 |
128 | 128 | 0.012 |
129 | 129 | 0.13 |
13 | 13 | 0.639 |
130 | 130 | 0.432 |
131 | 131 | 0.0969 |
132 | 132 | 0.498 |
133 | 133 | 0.858 |
134 | 134 | 0.972 |
135 | 135 | 0.843 |
136 | 136 | 0.459 |
137 | 137 | 0.759 |
138 | 138 | 0.621 |
139 | 139 | 0.0036 |
14 | 14 | 0.426 |
140 | 140 | 0.273 |
141 | 141 | 0.142 |
142 | 142 | 0.913 |
143 | 143 | 0.265 |
144 | 144 | 0.941 |
145 | 145 | 0.851 |
146 | 146 | 0.271 |
147 | 147 | 0.116 |
148 | 148 | 0.0451 |
149 | 149 | 0.398 |
15 | 15 | 0.0219 |
150 | 150 | 0.345 |
151 | 151 | 0.0805 |
152 | 152 | 0.837 |
153 | 153 | 0.446 |
154 | 154 | 0.376 |
155 | 155 | 0.0308 |
156 | 156 | 0.291 |
157 | 157 | 0.2 |
158 | 158 | 0.0436 |
159 | 159 | 0.993 |
16 | 16 | 0.936 |
160 | 160 | 0.266 |
161 | 161 | 0.14 |
162 | 162 | 0.569 |
163 | 163 | 0.745 |
164 | 164 | 0.941 |
165 | 165 | 0.235 |
166 | 166 | 0.0803 |
167 | 167 | 0.146 |
168 | 168 | 0.878 |
169 | 169 | 0.828 |
17 | 17 | 0.656 |
18 | 18 | 0.753 |
19 | 19 | 0.565 |
2 | 2 | 0.836 |
20 | 20 | 0.765 |
21 | 21 | 0.851 |
22 | 22 | 0.792 |
23 | 23 | 0.592 |
24 | 24 | 0.358 |
25 | 25 | 0.117 |
26 | 26 | 0.91 |
27 | 27 | 0.504 |
28 | 28 | 0.632 |
29 | 29 | 0.892 |
3 | 3 | 0.463 |
30 | 30 | 0.549 |
31 | 31 | 0.509 |
32 | 32 | 1.47759e-6 |
33 | 33 | 0.361 |
34 | 34 | 0.786 |
35 | 35 | 0.104 |
36 | 36 | 0.0461 |
37 | 37 | 0.665 |
38 | 38 | 0.348 |
39 | 39 | 0.887 |
4 | 4 | 0.44 |
40 | 40 | 0.118 |
41 | 41 | 0.378 |
42 | 42 | 0.254 |
43 | 43 | 0.295 |
44 | 44 | 0.365 |
45 | 45 | 0.396 |
46 | 46 | 0.344 |
47 | 47 | 0.179 |
48 | 48 | 0.504 |
49 | 49 | 0.0786 |
5 | 5 | 0.437 |
50 | 50 | 0.665 |
51 | 51 | 0.327 |
52 | 52 | 0.345 |
53 | 53 | 0.261 |
54 | 54 | 0.363 |
55 | 55 | 0.702 |
56 | 56 | 0.46 |
57 | 57 | 0.619 |
58 | 58 | 0.0986 |
59 | 59 | 0.304 |
6 | 6 | 0.905 |
60 | 60 | 0.106 |
61 | 61 | 0.32 |
62 | 62 | 0.0819 |
63 | 63 | 0.552 |
64 | 64 | 0.168 |
65 | 65 | 0.357 |
66 | 66 | 0.895 |
67 | 67 | 0.66 |
68 | 68 | 0.877 |
69 | 69 | 0.791 |
7 | 7 | 0.0736 |
70 | 70 | 0.0158 |
71 | 71 | 0.657 |
72 | 72 | 0.173 |
73 | 73 | 0.89 |
74 | 74 | 0.16 |
75 | 75 | 0.206 |
76 | 76 | 0.933 |
77 | 77 | 0.987 |
78 | 78 | 0.0315 |
79 | 79 | 0.217 |
8 | 8 | 0.226 |
80 | 80 | 0.321 |
81 | 81 | 0.386 |
82 | 82 | 0.246 |
83 | 83 | 0.2 |
84 | 84 | 0.552 |
85 | 85 | 0.228 |
86 | 86 | 0.903 |
87 | 87 | 0.828 |
88 | 88 | 0.735 |
89 | 89 | 0.358 |
9 | 9 | 0.919 |
90 | 90 | 0.0838 |
91 | 91 | 0.937 |
92 | 92 | 0.296 |
93 | 93 | 0.623 |
94 | 94 | 0.192 |
95 | 95 | 0.446 |
96 | 96 | 0.341 |
97 | 97 | 0.733 |
98 | 98 | 0.126 |
99 | 99 | 0.183 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12399
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000667 human Fibroblast - skin dystrophia myotonica, nuclear fraction sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
DOID: Disease
4 (disease)
17 (musculoskeletal system disease)
450 (myotonic disease)
7 (disease of anatomical entity)
66 (muscle tissue disease)
423 (myopathy)
0080000 (muscular disease)
11722 (myotonic dystrophy)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000408 (cellular fractionation sample)
0000350 (experimentally modified sample)
0000253 (human fibroblast- skin dystrophia myotonica sample)
0000406 (nuclear fraction sample)
0000667 (human Fibroblast - skin dystrophia myotonica, nuclear fraction sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)