CL:0000553: Difference between revisions
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|id=CL:0000553 | |id=CL:0000553 | ||
|name=megakaryocyte progenitor cell | |name=megakaryocyte progenitor cell | ||
|namespace=efo | |namespace=cell;;efo | ||
|def="The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] | |def="The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] | ||
|xref=BTO:0001164;;FMA:84235 | |xref=BTO:0001164;;FMA:84235 | ||
| Line 14: | Line 14: | ||
|obo_creation_date= | |obo_creation_date= | ||
|subset= | |subset= | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from= | ||
|has_quality= | |has_quality= | ||
|located_in= | |located_in= | ||
|part_of= | |part_of= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | ||
|is_obsolete= | |is_obsolete= | ||
|preceded_by= | |preceded_by= | ||
}} | }} | ||
Revision as of 17:25, 26 June 2012
| Name: | megakaryocyte progenitor cell | ||
|---|---|---|---|
| Namespace: | cell;;efo | ||
| Definition: | "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] | ||
| Xrefs: |
| ||
| Synonyms: |
"CFU-Meg" EXACT [PMID:11722431, PMID:12482498] "colony-forming unit-megakaryocyte" EXACT [] "Meg-CFC" EXACT [PMCID:PMC1794060] "megacaryoblast" EXACT [] "megacaryocyte progenitor cell" EXACT [] "megakaryoblast" EXACT [] "megakaryocytic progenitor cell" EXACT [PMID:12482498] "promegacaryocyte" RELATED [] "promegakaryocyte" RELATED [] | ||
| Comments: | Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000839(myeloid lineage restricted progenitor cell) |
|---|
Children
| is a: | CL:0002024 (Kit-positive megakaryocyte progenitor cell) |
|---|---|
| develops from: | CL:0000556 (megakaryocyte) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000553 (megakaryocyte progenitor cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.0e-60 | FFCP PHASE2:Mm9::chr3:40893940..40893948,+#_870ee79bf8670f6927cb44737baf3c01 | p@chr3:40893940..40893948, + |
| 1.0e-60 | FFCP PHASE1:Mm9::chr3:40893940..40893948,+#_870ee79bf8670f6927cb44737baf3c01 | p@chr3:40893940..40893948, + |
| 2.34e-60 | FFCP PHASE2:Mm9::chr6:68860437..68860451,-#_c55795c925c1953aeb4a336479cb1955 | p@chr6:68860437..68860451, - |
| 2.34e-60 | FFCP PHASE1:Mm9::chr6:68860437..68860451,-#_c55795c925c1953aeb4a336479cb1955 | p@chr6:68860437..68860451, - |
| 3.38e-58 | FFCP PHASE1:Mm9::chr3:41343162..41343165,+#_51d8887eb0b704903aea91d87734d301 | p@chr3:41343162..41343165, + |
| 3.38e-58 | FFCP PHASE2:Mm9::chr3:41343162..41343165,+#_51d8887eb0b704903aea91d87734d301 | p@chr3:41343162..41343165, + |
| 3.91e-58 | FFCP PHASE2:Mm9::chr9:108276696..108276698,+#_00c68f64d87039bc7379f9a4958b8ad1 | p@chr9:108276696..108276698, + |
| 3.91e-58 | FFCP PHASE1:Mm9::chr9:108276696..108276698,+#_00c68f64d87039bc7379f9a4958b8ad1 | p@chr9:108276696..108276698, + |
| 4.23e-58 | FFCP PHASE1:Mm9::chr2:98503916..98503926,+#_89245964831126fb37531ce19e9a05da | p@chr2:98503916..98503926, + |
| 4.23e-58 | FFCP PHASE2:Mm9::chr2:98503916..98503926,+#_89245964831126fb37531ce19e9a05da | p@chr2:98503916..98503926, + |
| 1.25e-52 | FFCP PHASE2:Mm9::chr4:105391511..105391533,+#_89ce68a7f9653f003f4ff92cd82fb1b7 | p@chr4:105391511..105391533, + |
| 1.25e-52 | FFCP PHASE1:Mm9::chr4:105391511..105391533,+#_89ce68a7f9653f003f4ff92cd82fb1b7 | p@chr4:105391511..105391533, + |
| 5.18e-52 | FFCP PHASE1:Mm9::chr6:69851116..69851126,-#_b9fba6f781bb072b3e1f9233b1e1a8e6 | p2@ENSMUST00000103370 |
| 5.18e-52 | FFCP PHASE2:Mm9::chr6:69851116..69851126,-#_b9fba6f781bb072b3e1f9233b1e1a8e6 | p2@ENSMUST00000103370 |
| 5.23e-52 | FFCP PHASE2:Mm9::chr10:41613773..41613784,+#_775900836efd06a8b686861be508b003 | p@chr10:41613773..41613784, + |
| 5.23e-52 | FFCP PHASE1:Mm9::chr10:41613773..41613784,+#_775900836efd06a8b686861be508b003 | p@chr10:41613773..41613784, + |
| 5.23e-52 | FFCP PHASE1:Mm9::chr17:34376620..34376634,-#_775900836efd06a8b686861be508b003 | p@chr17:34376620..34376634, - |
| 5.23e-52 | FFCP PHASE2:Mm9::chr17:34376620..34376634,-#_775900836efd06a8b686861be508b003 | p@chr17:34376620..34376634, - |
| 1.08e-51 | FFCP PHASE2:Mm9::chr9:32425275..32425296,+#_0a97d838c42178f12ed85e584a6b51dd | p@chr9:32425275..32425296, + |
| 1.08e-51 | FFCP PHASE1:Mm9::chr9:32425275..32425296,+#_0a97d838c42178f12ed85e584a6b51dd | p@chr9:32425275..32425296, + |
| 1.74e-51 | FFCP PHASE2:Mm9::chr6:70676952..70676959,-#_bb1d6a7b14546f704f7c161df98c1d3c | p@chr6:70676952..70676959, - |
| 1.74e-51 | FFCP PHASE1:Mm9::chr6:70676952..70676959,-#_bb1d6a7b14546f704f7c161df98c1d3c | p@chr6:70676952..70676959, - |
| 6.51e-48 | FFCP PHASE2:Mm9::chr17:88981299..88981314,+#_29758e29c728b1d3062cf77b12cfa578 | p@chr17:88981299..88981314, + |
| 6.51e-48 | FFCP PHASE1:Mm9::chr17:88981299..88981314,+#_29758e29c728b1d3062cf77b12cfa578 | p@chr17:88981299..88981314, + |
| 1.98e-47 | FFCP PHASE2:Mm9::chr12:48935035..48935049,+#_041c49995a7ddb259be095831b148eac | p@chr12:48935035..48935049, + |
| 1.98e-47 | FFCP PHASE1:Mm9::chr12:48935035..48935049,+#_041c49995a7ddb259be095831b148eac | p@chr12:48935035..48935049, + |
| 8.31e-47 | FFCP PHASE1:Mm9::chr11:96193855..96193860,+#_0b1d2c035d00c5193b7bdb6ea522879d | p@chr11:96193855..96193860, + |
| 8.31e-47 | FFCP PHASE2:Mm9::chr11:96193855..96193860,+#_0b1d2c035d00c5193b7bdb6ea522879d | p@chr11:96193855..96193860, + |
| 8.31e-47 | FFCP PHASE2:Mm9::chr13:30095274..30095283,+#_0b1d2c035d00c5193b7bdb6ea522879d | p@chr13:30095274..30095283, + |
| 8.31e-47 | FFCP PHASE1:Mm9::chr13:30095274..30095283,+#_0b1d2c035d00c5193b7bdb6ea522879d | p@chr13:30095274..30095283, + |
| 1.42e-46 | FFCP PHASE2:Mm9::chr19:11463663..11463671,+#_2439f36cb52c02793615004637aac939 | p@chr19:11463663..11463671, + |
| 1.42e-46 | FFCP PHASE1:Mm9::chr19:11463663..11463671,+#_2439f36cb52c02793615004637aac939 | p@chr19:11463663..11463671, + |
| 1.86e-46 | FFCP PHASE1:Mm9::chr13:112658212..112658227,+#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p3@ENSMUST00000128198, p3@uc007rwb.1 |
| 1.86e-46 | FFCP PHASE2:Mm9::chr3:58321410..58321423,+#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p@chr3:58321410..58321423, + |
| 1.86e-46 | FFCP PHASE1:Mm9::chr17:34400036..34400056,-#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p@chr17:34400036..34400056, - |
| 1.86e-46 | FFCP PHASE2:Mm9::chr17:34400036..34400056,-#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p@chr17:34400036..34400056, - |
| 1.86e-46 | FFCP PHASE2:Mm9::chr13:112658212..112658227,+#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p3@ENSMUST00000128198, p3@uc007rwb.1 |
| 1.86e-46 | FFCP PHASE1:Mm9::chr3:58321410..58321423,+#_b9c0a7bd86d8ad72ad02afe6b153ee77 | p@chr3:58321410..58321423, + |
| 9.65e-46 | FFCP PHASE2:Mm9::chr16:19200368..19200390,-#_3a27bc10ac07afdaa2bb8989ca15e31c | p2@ENSMUST00000103749 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr2:99640370..99640374,+#_3a27bc10ac07afdaa2bb8989ca15e31c | p@chr2:99640370..99640374, + |
| 9.65e-46 | FFCP PHASE2:Mm9::chr4:135451095..135451110,+#_3a27bc10ac07afdaa2bb8989ca15e31c | p4@Cnr2 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr4:135451095..135451110,+#_3a27bc10ac07afdaa2bb8989ca15e31c | p4@Cnr2 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr12:114659326..114659343,-#_3a27bc10ac07afdaa2bb8989ca15e31c | p5@uc007pgs.1 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr2:99640370..99640374,+#_3a27bc10ac07afdaa2bb8989ca15e31c | p@chr2:99640370..99640374, + |
| 9.65e-46 | FFCP PHASE1:Mm9::chr12:114659326..114659343,-#_3a27bc10ac07afdaa2bb8989ca15e31c | p5@uc007pgs.1 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr16:19200368..19200390,-#_3a27bc10ac07afdaa2bb8989ca15e31c | p2@ENSMUST00000103749 |
| 1.19e-45 | FFCP PHASE1:Mm9::chr12:100880892..100880902,-#_8feeb532524861d0650bd1e358f730bb | p@chr12:100880892..100880902, - |
| 1.19e-45 | FFCP PHASE2:Mm9::chr12:100880892..100880902,-#_8feeb532524861d0650bd1e358f730bb | p@chr12:100880892..100880902, - |
| 1.82e-45 | FFCP PHASE1:Mm9::chr9:32460050..32460070,+#_5e34e52e62fac4ca9288b197ce34fa27 | p@chr9:32460050..32460070, + |
| 1.82e-45 | FFCP PHASE2:Mm9::chr9:32460050..32460070,+#_5e34e52e62fac4ca9288b197ce34fa27 | p@chr9:32460050..32460070, + |
| 2.38e-44 | FFCP PHASE2:Mm9::chr12:114659633..114659652,-#_28ef2acc39e7a9a95aac78364a0b1c32 | p4@uc007pgs.1 |
| 2.38e-44 | FFCP PHASE1:Mm9::chr12:114659633..114659652,-#_28ef2acc39e7a9a95aac78364a0b1c32 | p4@uc007pgs.1 |
| 2.38e-44 | FFCP PHASE1:Mm9::chr9:32487351..32487367,+#_28ef2acc39e7a9a95aac78364a0b1c32 | p@chr9:32487351..32487367, + |
| 2.38e-44 | FFCP PHASE2:Mm9::chr9:32487351..32487367,+#_28ef2acc39e7a9a95aac78364a0b1c32 | p@chr9:32487351..32487367, + |
| 3.35e-44 | FFCP PHASE1:Mm9::chr5:122674421..122674426,+#_85a8c6c1a9b1d26521167ce3af376be6 | p@chr5:122674421..122674426, + |
| 3.35e-44 | FFCP PHASE2:Mm9::chr5:122674421..122674426,+#_85a8c6c1a9b1d26521167ce3af376be6 | p@chr5:122674421..122674426, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr18:35809146..35809153,-#_7076bffd597815ecd2325fc938467866 | p4@2010001M09Rik |
| 5.38e-44 | FFCP PHASE1:Mm9::chr1:156964198..156964201,+#_7076bffd597815ecd2325fc938467866 | p@chr1:156964198..156964201, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr4:44980637..44980644,+#_7076bffd597815ecd2325fc938467866 | p4@ENSMUST00000150111 |
| 5.38e-44 | FFCP PHASE1:Mm9::chr4:59740918..59740923,+#_7076bffd597815ecd2325fc938467866 | p@chr4:59740918..59740923, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr18:35809146..35809153,-#_7076bffd597815ecd2325fc938467866 | p4@2010001M09Rik |
| 5.38e-44 | FFCP PHASE2:Mm9::chr4:44980637..44980644,+#_7076bffd597815ecd2325fc938467866 | p4@ENSMUST00000150111 |
| 5.38e-44 | FFCP PHASE1:Mm9::chr11:102210718..102210728,-#_7076bffd597815ecd2325fc938467866 | p@chr11:102210718..102210728, - |
| 5.38e-44 | FFCP PHASE2:Mm9::chr18:55201820..55201826,+#_7076bffd597815ecd2325fc938467866 | p@chr18:55201820..55201826, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr6:135966781..135966785,+#_7076bffd597815ecd2325fc938467866 | p@chr6:135966781..135966785, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr19:43721970..43721975,+#_7076bffd597815ecd2325fc938467866 | p@chr19:43721970..43721975, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr11:102210718..102210728,-#_7076bffd597815ecd2325fc938467866 | p@chr11:102210718..102210728, - |
| 5.38e-44 | FFCP PHASE1:Mm9::chr17:84975629..84975633,+#_7076bffd597815ecd2325fc938467866 | p@chr17:84975629..84975633, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr6:135966781..135966785,+#_7076bffd597815ecd2325fc938467866 | p@chr6:135966781..135966785, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr17:84975629..84975633,+#_7076bffd597815ecd2325fc938467866 | p@chr17:84975629..84975633, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr4:59740918..59740923,+#_7076bffd597815ecd2325fc938467866 | p@chr4:59740918..59740923, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr19:43721970..43721975,+#_7076bffd597815ecd2325fc938467866 | p@chr19:43721970..43721975, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr18:55201820..55201826,+#_7076bffd597815ecd2325fc938467866 | p@chr18:55201820..55201826, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr1:156964198..156964201,+#_7076bffd597815ecd2325fc938467866 | p@chr1:156964198..156964201, + |
| 6.62e-44 | FFCP PHASE2:Mm9::chr17:34282256..34282276,+#_61b855da092991876771f8c21006a357 | p4@H2-DMb2 |
| 6.62e-44 | FFCP PHASE1:Mm9::chr17:34282256..34282276,+#_61b855da092991876771f8c21006a357 | p4@H2-DMb2 |
| 2.83e-41 | FFCP PHASE2:Mm9::chr12:114660740..114660753,+#_2fe0ae9b0e77d1d5d3eca9954c522a16 | p@chr12:114660740..114660753, + |
| 2.83e-41 | FFCP PHASE1:Mm9::chr12:114660740..114660753,+#_2fe0ae9b0e77d1d5d3eca9954c522a16 | p@chr12:114660740..114660753, + |
| 4.64e-41 | FFCP PHASE2:Mm9::chr19:21705252..21705273,-#_a503ecf78ca33556a6ff64359b08305a | p@chr19:21705252..21705273, - |
| 4.64e-41 | FFCP PHASE1:Mm9::chr19:21705252..21705273,-#_a503ecf78ca33556a6ff64359b08305a | p@chr19:21705252..21705273, - |
| 7.27e-41 | FFCP PHASE2:Mm9::chr12:114652607..114652619,-#_0ede2ca0d677d36344fd98a823ac3305 | p@chr12:114652607..114652619, - |
| 7.27e-41 | FFCP PHASE1:Mm9::chr12:114652607..114652619,-#_0ede2ca0d677d36344fd98a823ac3305 | p@chr12:114652607..114652619, - |
| 8.77e-41 | FFCP PHASE2:Mm9::chr13:30095241..30095252,+#_05dca6394f1dff04c4e76d92247963a6 | p@chr13:30095241..30095252, + |
| 8.77e-41 | FFCP PHASE2:Mm9::chr18:36069982..36069991,+#_05dca6394f1dff04c4e76d92247963a6 | p@chr18:36069982..36069991, + |
| 8.77e-41 | FFCP PHASE1:Mm9::chr13:30095241..30095252,+#_05dca6394f1dff04c4e76d92247963a6 | p@chr13:30095241..30095252, + |
| 8.77e-41 | FFCP PHASE1:Mm9::chr18:36069982..36069991,+#_05dca6394f1dff04c4e76d92247963a6 | p@chr18:36069982..36069991, + |
| 1.02e-40 | FFCP PHASE2:Mm9::chr12:53180087..53180104,+#_5e23c1ad39181c1ddd1e5497f6952b75 | p@chr12:53180087..53180104, + |
| 1.02e-40 | FFCP PHASE1:Mm9::chr12:114659852..114659872,+#_5e23c1ad39181c1ddd1e5497f6952b75 | p@chr12:114659852..114659872, + |
| 1.02e-40 | FFCP PHASE1:Mm9::chr12:53180087..53180104,+#_5e23c1ad39181c1ddd1e5497f6952b75 | p@chr12:53180087..53180104, + |
| 1.02e-40 | FFCP PHASE2:Mm9::chr12:114659852..114659872,+#_5e23c1ad39181c1ddd1e5497f6952b75 | p@chr12:114659852..114659872, + |
| 1.06e-40 | FFCP PHASE1:Mm9::chr10:50076400..50076404,+#_d2ac5d2b8188a524708b108e73286cfb | p@chr10:50076400..50076404, + |
| 1.06e-40 | FFCP PHASE2:Mm9::chr10:50076400..50076404,+#_d2ac5d2b8188a524708b108e73286cfb | p@chr10:50076400..50076404, + |
| 1.91e-40 | FFCP PHASE1:Mm9::chr8:70480444..70480457,+#_67061e9276cd7d62ef3c45864cf3680c | p2@ENSMUST00000127631 |
| 1.91e-40 | FFCP PHASE2:Mm9::chr8:70480444..70480457,+#_67061e9276cd7d62ef3c45864cf3680c | p2@ENSMUST00000127631 |
| 4.18e-40 | FFCP PHASE1:Mm9::chr6:70676615..70676621,+#_614e7e8306842c5d5dbb57af624fa4b9 | p@chr6:70676615..70676621, + |
| 4.18e-40 | FFCP PHASE2:Mm9::chr6:70676615..70676621,+#_614e7e8306842c5d5dbb57af624fa4b9 | p@chr6:70676615..70676621, + |
| 2.4e-39 | FFCP PHASE1:Mm9::chr1:134238914..134238921,+#_bc04fdf92a2c4ebe1baae3e3c517f793 | p@chr1:134238914..134238921, + |
| 2.4e-39 | FFCP PHASE1:Mm9::chr12:100880924..100880933,-#_bc04fdf92a2c4ebe1baae3e3c517f793 | p@chr12:100880924..100880933, - |
| 2.4e-39 | FFCP PHASE2:Mm9::chr1:134238914..134238921,+#_bc04fdf92a2c4ebe1baae3e3c517f793 | p@chr1:134238914..134238921, + |
| 2.4e-39 | FFCP PHASE2:Mm9::chr12:100880924..100880933,-#_bc04fdf92a2c4ebe1baae3e3c517f793 | p@chr12:100880924..100880933, - |
