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Coexpression cluster:C1773: Difference between revisions

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|full_id=C1773_smooth_heart_sacrococcigeal_aorta_bladder_basal_rectum
|full_id=C1773_smooth_heart_sacrococcigeal_aorta_bladder_basal_rectum
|id=C1773
|id=C1773
|ontology_enrichment_celltype=CL:0000359!6.42e-13!32;CL:0000192!7.57e-12!42;CL:0000514!7.57e-12!42;CL:0000055!2.37e-09!180;CL:0000680!3.20e-09!57;CL:0000056!3.20e-09!57;CL:0000355!3.20e-09!57;CL:0000187!1.37e-08!54;CL:0000393!1.96e-08!60;CL:0000211!1.96e-08!60;CL:0000183!2.44e-08!59;CL:0002539!7.04e-07!10
|ontology_enrichment_celltype=CL:0000359!5.03e-12!32;CL:0000192!4.19e-10!43;CL:0000514!4.19e-10!43;CL:0002539!5.06e-07!10
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!7.75e-25!115;UBERON:0000481!3.50e-15!347;UBERON:0000468!9.68e-13!659;UBERON:0000477!4.67e-12!286;UBERON:0002385!8.73e-12!63;UBERON:0001015!8.73e-12!63;UBERON:0000383!8.73e-12!63;UBERON:0000914!2.03e-11!83;UBERON:0002329!2.03e-11!83;UBERON:0003077!2.03e-11!83;UBERON:0003059!2.03e-11!83;UBERON:0007282!2.03e-11!83;UBERON:0009618!2.03e-11!83;UBERON:0007285!2.03e-11!83;UBERON:0000475!2.12e-11!365;UBERON:0001134!1.09e-10!61;UBERON:0002036!1.09e-10!61;UBERON:0003082!1.09e-10!61;UBERON:0004111!2.12e-10!241;UBERON:0004872!4.52e-10!84;UBERON:0000025!3.68e-09!194;UBERON:0004290!1.19e-08!70;UBERON:0001135!1.32e-08!15;UBERON:0000119!1.79e-08!312;UBERON:0000483!2.01e-08!309;UBERON:0000467!2.22e-08!625;UBERON:0000480!3.00e-08!626;UBERON:0001637!3.54e-08!42;UBERON:0003509!3.54e-08!42;UBERON:0004572!3.54e-08!42;UBERON:0004573!3.79e-08!33;UBERON:0004571!3.79e-08!33;UBERON:0000922!8.27e-08!612;UBERON:0005256!1.03e-07!143;UBERON:0001049!1.47e-07!57;UBERON:0005068!1.47e-07!57;UBERON:0006241!1.47e-07!57;UBERON:0007135!1.47e-07!57;UBERON:0001981!2.05e-07!60;UBERON:0007500!2.05e-07!60;UBERON:0004537!2.05e-07!60;UBERON:0006965!2.05e-07!60;UBERON:0000486!3.36e-07!82;UBERON:0003075!3.47e-07!86;UBERON:0007284!3.47e-07!86;UBERON:0004237!7.04e-07!10;UBERON:0004695!7.04e-07!10;UBERON:0002111!7.04e-07!10;UBERON:0004178!7.04e-07!10;UBERON:0002346!7.10e-07!90;UBERON:0002050!7.16e-07!605;UBERON:0005423!7.16e-07!605;UBERON:0007100!9.08e-07!27
|ontology_enrichment_uberon=UBERON:0007023!5.77e-23!114;UBERON:0000481!1.10e-10!342;UBERON:0001637!1.17e-09!42;UBERON:0003509!1.17e-09!42;UBERON:0004572!1.17e-09!42;UBERON:0004872!2.07e-09!83;UBERON:0004573!6.51e-09!33;UBERON:0004571!6.51e-09!33;UBERON:0002385!7.89e-09!64;UBERON:0001015!7.89e-09!64;UBERON:0000383!7.89e-09!64;UBERON:0000477!1.32e-08!373;UBERON:0007500!3.29e-08!59;UBERON:0001981!3.29e-08!59;UBERON:0004537!3.29e-08!59;UBERON:0006965!3.29e-08!59;UBERON:0001135!3.41e-08!15;UBERON:0003104!4.66e-08!160;UBERON:0009142!4.66e-08!160;UBERON:0007524!1.03e-07!73;UBERON:0001134!1.45e-07!62;UBERON:0002036!1.45e-07!62;UBERON:0003082!1.45e-07!62;UBERON:0003077!2.72e-07!72;UBERON:0007285!2.72e-07!72;UBERON:0005256!2.84e-07!122;UBERON:0000468!4.98e-07!656;UBERON:0004237!5.06e-07!10;UBERON:0004695!5.06e-07!10;UBERON:0002111!5.06e-07!10;UBERON:0004178!5.06e-07!10;UBERON:0002329!6.21e-07!71;UBERON:0003059!6.21e-07!71;UBERON:0007282!6.21e-07!71;UBERON:0004290!6.21e-07!71;UBERON:0009618!6.21e-07!71;UBERON:0003101!7.03e-07!22;UBERON:0000079!7.03e-07!22;UBERON:0004111!7.37e-07!240
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686,0.425114,0.7034,0.218241,0.0242146,0.10708,0.327369,0.339826,0.12998,0.123097,0.254847,0.300809,0.0898207,0.126545,0.00435603,0.0686325,0.0569043,0.0639461,0.0871536,0.267408,0.312064,0.080156,0.0415903,0.53753,0.0545112,0.510703,0.0651134,0.0649137,0.0974216,0.0137454,0.195675,0.174786,0.176557,0.396547,0.0472148,0.000458308,0.229138,0.0639045,0.141461,0.0900204,0.00239454,0.385962,0.334921,0.296227,0.208788,0.0104864,0.36304,0.00269279,0.123626,0.270619,0.132705,0.285556,0.148915,0.233835,0.00226547,0.262929,0.223204,0.143824,0.460679,0.431098,0.0775891,0.153079,0.0179567,0.211515,0.125701,0.175283,0.00169473,0.209341,0.855975,0.629422,0.084895,0.160115,0.0819954,0.10091,0.122658,0.151161,0.228398,0.056055,0.00757731,0.102815,0.893893,0.830533,0.335207,0.434016,0.190688,0.299739,0.278645,0.733648,0.0940982,0.0780533,0.564811,0.0993772,0.274769,0.0227103,0.11602,0.344528,0.436413,0.0585992,0.20045,0.274438,0.573835,0.0445114,0.319826,0.0643195,0.173868,0.109708,0.174594,0.0809806,0.154589,0.318794,0.122767,0.0749261,0.176858,0.114361,0.347759,0.242462,0.0620267,0.211111,0.0738743,0.0882327,0.183058,0.150073,0.270522,0.16872,0.341388,0.0934526,0.359135,0.123404,0.430769,0.240825,0.3033,0.336623,0.163542,0.483244,0.27134,0.500871,0.239667,0.10226,0.29809,0.235147,0.689826,0.245965,0.116923,0.148426,0.0983658,0.228743,0.000183911,0.156976,0.244789,0.0394446,0.0508431,0.21807,0.350528,0.382904,0.432408,0.190404,0.135865,0.145815,0.18137,0.180609,0.291283,0.273972,0.153023,0.400137,0.37958,0.22307,0.160699,0.0891264,0.166736,0.181253,0.0422294,0.263877,0.146486,0.769574,0.262486,0.294204,0.131936,0.288826,0.246621,4.19643e-06,0.697373,0.0965376,0.377203,0.279263,0.336564,0.0720023,0.581771,0.47901,0.0594155,0.222245,0.208795,0.0713793,0.0244015,0.594469,0.000148381,0.0791056,0.0583216,0.355154,0.0442628,0.0169199,0.0432366,0.603804,0.261576,0.306963,0.569605,0.526495,0.580285,0.550495,0.0592373,0.0309224,0.00285624,0.0219218,0.561689,0.672416,0.0301736,0.255366,0.708698,0.96913,0.663441,0.349068,0.00823428,0.000263951,0.557035,0.0191917,0.0313227,0.0025692,0.00185459,0.433702,0.258394,0.644878,0.432123,0.759415,0.0245793,0.494975,0.651196,0.392155,0.626931,0.371758,0.0422618,0.20076,0.183098,0.128028,0.254547,0.204391,0.821811,0.680843,0.500384,0.541378,0.725301,0.660884,0.922144,0.000622926,0.705225,0.000636369,4.4118e-05,0.318577,0.4488,0.389888,0.603509,7.16296e-08,0.0014547,0.246387,0.224252,0.587237,0.155054,0.466978,0.518234,0.257848,0.353942,0.192234,0.427276,0.747776,0.466967,0.283682,0.424668,0.247468,0.078383,0.583101,0.00804138,0.00440505,0.263776,0.033063,0.792095,0.197115,0.349033,0.50651,0.367723,0.34194,0.592696,0.592314,0.644904,0.0254154,0.763919,0.317485,0.633504,0.220564,0.845182,0.262394,2.49539e-06,0.135076,0.133253,0.664443,0.274593,0.490712,0.541363,0.0369687,0.583627,0.531474,0.000360372,0.200667,0.0407909,0.361524,0.31558,0.412744,0.54408,0.62698,0.000893539,0.415367,6.88639e-05,0.45585,0.36864,0.538745,0.000426199,0.453004,2.61087e-05,0.557093,0.693441,0.382214,0.553161,0.0841037,0.68995,0.339393,3.40276e-05,0.306231,0.298354,0.00428643,0.0701109,0.125872,0.641611,0.426239,2.4926e-07,0.656093,0.572661,0.412586,0.534679,0.41502,0.00943394,0.66153,0.523749,0.499347,0.307426,0.00539033,0.000204601,0.490527,0.0384956,0.44799,0.00173749,0.318338,0.276338,0.126433,2.17889e-05,0.318174,0.0555558,0.295666,0.393022,0.293641,0.116969,0.401231,0.255983,4.40464e-09,0.256708,0.338258,0.322052,0.145568,0.153833,0.261242,0.00156127,0.00878877,0.0877196,0.0582761,0.627637,0.280757,0.301366,0.340343,0.343265,0.501812,0.0251441,0.336254,0.308589,0.00528043,0.19697,0.309816,0.0537285,0.15063,0.198077,0.281455,0.00956309,0.419895,0.138495,0.0235054,0.32256,0.377566,0.342366,0.109684,0.322704,0.00019998,5.68657e-05,0.230841,0.352328,0.255358,0.351665,0.265112,0.0633313,0.10772,0.0854747,2.21266e-08,0.406458,0.312881,0.512825,0.244656,3.09042e-06,0.158985,0.174153,0.0972854,0.333309,0.249919,0.339517,1.1779e-07,0.198326,0.394084,0.458518,0.000388656,0.252005,0.000165514,0.238377,0.00835901,0.197875,2.83764e-05,0.289389,0.117618,0.392533,0.396962,0.00688664,0.330317,0.321404,0.225079,0.00051193,0.379651,0.185715,0.345505,0.375521,0.0407047,0.311201,0.221943,0.306427,0.367733,0.246925,0.208775,0.0140126,0.343014,0.000318673,0.276922,0.0129027,0.000619861,0.000455273,0.422872,0.336468,0.13327,0.313545,0.0156255,0.0877361,0.0880065,0.238969,0.126615,0.0669467,0.0879453,0.474066,0.396935,3.80176e-06,0.292869,0.358198,0.29552,0.131776,0.158116,0.104606,0.194814,0.104167,0.168186,0.108081,0.123829,0.00170161,0.175247,1.88087e-08,0.109077,0.144842,0.0604892,0.214671,0.316879,0.442567,0.000295973,0.508546,0.224871,1.56404e-05,0.088016,0.0542381,0.349611,0.445995,0.0134421,0.0045314,0.426488,0.400591,0.209809,0.253154,0.319519,0.309489,0.430805,7.82111e-06,0.480785,0.185476,0.0642384,0.344469,0.184651,0.303359,0.297596,0.018596,1.36485e-07,0.380826,0.259046,0.345068,0.151046,0.483953,0.347171,0.321735,0.15463,0.13907,4.75608e-06,0.269432,0.0343725,0.409882,0.115686,0.408975,0.162633,0.342661,0.27567,0.248127,0.33299,0.384731,0.319112,0.526476
}}
}}

Revision as of 11:40, 19 October 2012


Full id: C1773_smooth_heart_sacrococcigeal_aorta_bladder_basal_rectum



Phase1 CAGE Peaks

Hg19::chr17:12569199..12569216,+p1@MYOCD
Hg19::chr17:12569325..12569344,+p2@MYOCD
Hg19::chr17:12569359..12569380,+p3@MYOCD
Hg19::chr17:12569384..12569402,+p4@MYOCD
Hg19::chr17:12569472..12569482,+p5@MYOCD


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
vascular associated smooth muscle cell5.03e-1232
smooth muscle cell4.19e-1043
smooth muscle myoblast4.19e-1043
aortic smooth muscle cell5.06e-0710
Uber Anatomy
Ontology termp-valuen
adult organism5.77e-23114
multi-tissue structure1.10e-10342
artery1.17e-0942
arterial blood vessel1.17e-0942
arterial system1.17e-0942
splanchnic layer of lateral plate mesoderm2.07e-0983
systemic artery6.51e-0933
systemic arterial system6.51e-0933
muscle tissue7.89e-0964
musculature7.89e-0964
musculature of body7.89e-0964
anatomical cluster1.32e-08373
epithelial tube open at both ends3.29e-0859
blood vessel3.29e-0859
blood vasculature3.29e-0859
vascular cord3.29e-0859
smooth muscle tissue3.41e-0815
mesenchyme4.66e-08160
entire embryonic mesenchyme4.66e-08160
dense mesenchyme tissue1.03e-0773
skeletal muscle tissue1.45e-0762
striated muscle tissue1.45e-0762
myotome1.45e-0762
paraxial mesoderm2.72e-0772
presumptive paraxial mesoderm2.72e-0772
trunk mesenchyme2.84e-07122
multi-cellular organism4.98e-07656
blood vessel smooth muscle5.06e-0710
arterial system smooth muscle5.06e-0710
artery smooth muscle tissue5.06e-0710
aorta smooth muscle tissue5.06e-0710
somite6.21e-0771
presomitic mesoderm6.21e-0771
presumptive segmental plate6.21e-0771
dermomyotome6.21e-0771
trunk paraxial mesoderm6.21e-0771
male organism7.03e-0722
male reproductive system7.03e-0722
anatomical conduit7.37e-07240


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.