Novel motif:19

name:	motif19_GYTGGMC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0070208	protein heterotrimerization	9.370542e-12
GO:0051291	protein heterooligomerization	2.025191e-10
GO:0046724	oxalic acid secretion	2.315408e-10
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	2.315408e-10
GO:0032964	collagen biosynthetic process	6.477638e-10
GO:0042744	hydrogen peroxide catabolic process	7.347922e-10
GO:0003108	negative regulation of the force of heart contraction by chemical signal	1.325009e-9
GO:0006548	histidine catabolic process	1.589984e-9
GO:0006779	porphyrin-containing compound biosynthetic process	1.958975e-9
GO:0000302	response to reactive oxygen species	3.556359e-9
GO:0016056	rhodopsin mediated signaling pathway	4.384889e-9
GO:0006545	glycine biosynthetic process	4.464329e-9
GO:0002679	respiratory burst involved in defense response	7.370515e-9
GO:0002149	hypochlorous acid biosynthetic process	8.290077e-9
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.677143e-8
GO:0042542	response to hydrogen peroxide	2.773756e-8
GO:0042743	hydrogen peroxide metabolic process	3.299819e-8
GO:0051295	establishment of meiotic spindle localization	3.402587e-8
GO:0010812	negative regulation of cell-substrate adhesion	7.442553e-8
GO:0032042	mitochondrial DNA metabolic process	8.716909e-8
GO:0060251	regulation of glial cell proliferation	9.925594e-8
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.027862e-7
GO:0070206	protein trimerization	1.140986e-7
GO:0032796	uropod organization	1.233994e-7
GO:0006982	response to lipid hydroperoxide	1.271585e-7
GO:0060253	negative regulation of glial cell proliferation	1.485177e-7
GO:0006544	glycine metabolic process	1.513093e-7
GO:0006707	cholesterol catabolic process	1.990649e-7
GO:0006264	mitochondrial DNA replication	2.149963e-7
GO:0007132	meiotic metaphase I	2.479590e-7
GO:0060730	regulation of intestinal epithelial structure maintenance	2.508561e-7
GO:0060456	positive regulation of digestive system process	2.620773e-7
GO:0007140	male meiosis	2.639288e-7
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	3.054737e-7
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	3.582485e-7
GO:0010624	regulation of Schwann cell proliferation	3.895941e-7
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	4.458400e-7
GO:0016125	sterol metabolic process	4.516893e-7
GO:0034465	response to carbon monoxide	5.050154e-7
GO:0071299	cellular response to vitamin A	5.536763e-7
GO:0071300	cellular response to retinoic acid	5.762012e-7
GO:0070715	sodium-dependent organic cation transport	6.165514e-7
GO:0052106	quorum sensing involved in interaction with host	6.165514e-7
GO:0060731	positive regulation of intestinal epithelial structure maintenance	6.165514e-7
GO:0042487	regulation of odontogenesis of dentine-containing tooth	7.138805e-7
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	7.285051e-7
GO:0006778	porphyrin-containing compound metabolic process	7.457370e-7
GO:0006706	steroid catabolic process	8.063082e-7
GO:0019884	antigen processing and presentation of exogenous antigen	8.495739e-7
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	9.084526e-7
GO:0009226	nucleotide-sugar biosynthetic process	1.062695e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.068629e-6
GO:0006547	histidine metabolic process	1.196274e-6
GO:0010872	regulation of cholesterol esterification	1.315088e-6
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	1.352280e-6
GO:0051954	positive regulation of amine transport	1.391415e-6
GO:0001768	establishment of T cell polarity	1.398406e-6
GO:0030007	cellular potassium ion homeostasis	1.497080e-6
GO:0042268	regulation of cytolysis	1.519034e-6
GO:0070544	histone H3-K36 demethylation	1.713642e-6
GO:0071731	response to nitric oxide	1.813751e-6
GO:0045794	negative regulation of cell volume	2.014398e-6
GO:0046487	glyoxylate metabolic process	2.044988e-6
GO:0042699	follicle-stimulating hormone signaling pathway	2.071308e-6
GO:0032526	response to retinoic acid	2.112297e-6
GO:0033189	response to vitamin A	2.394585e-6
GO:0046314	phosphocreatine biosynthetic process	2.446158e-6
GO:0033013	tetrapyrrole metabolic process	2.717362e-6
GO:0019673	GDP-mannose metabolic process	2.996501e-6
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.203428e-6
GO:0046501	protoporphyrinogen IX metabolic process	3.557888e-6
GO:0016446	somatic hypermutation of immunoglobulin genes	3.736004e-6
GO:0002238	response to molecule of fungal origin	4.278265e-6
GO:0006884	cell volume homeostasis	4.597063e-6
GO:0071732	cellular response to nitric oxide	5.035961e-6
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	5.037482e-6
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	5.037482e-6
GO:0055075	potassium ion homeostasis	5.348750e-6
GO:0002579	positive regulation of antigen processing and presentation	5.475206e-6
GO:0006783	heme biosynthetic process	5.697809e-6
GO:0007126	meiosis	7.008172e-6
GO:0010626	negative regulation of Schwann cell proliferation	7.019724e-6
GO:0010873	positive regulation of cholesterol esterification	7.186854e-6
GO:0051323	metaphase	7.525071e-6
GO:0051321	meiotic cell cycle	7.526622e-6
GO:0000212	meiotic spindle organization	7.544604e-6
GO:0019835	cytolysis	7.620994e-6
GO:0071827	plasma lipoprotein particle organization	7.875475e-6
GO:0006772	thiamine metabolic process	8.077118e-6
GO:0031442	positive regulation of mRNA 3'-end processing	8.109571e-6
GO:0043585	nose morphogenesis	8.212396e-6
GO:0002906	negative regulation of mature B cell apoptosis	8.385286e-6
GO:0006013	mannose metabolic process	8.824891e-6
GO:0019511	peptidyl-proline hydroxylation	9.108191e-6
GO:0009070	serine family amino acid biosynthetic process	9.545608e-6
GO:0009155	purine deoxyribonucleotide catabolic process	9.825831e-6
GO:0034505	tooth mineralization	1.077863e-5
GO:2000427	positive regulation of apoptotic cell clearance	1.083738e-5
GO:0009301	snRNA transcription	1.098866e-5
GO:0050768	negative regulation of neurogenesis	1.108594e-5
GO:0070904	transepithelial L-ascorbic acid transport	1.108599e-5
GO:0060014	granulosa cell differentiation	1.154446e-5
GO:0042866	pyruvate biosynthetic process	1.154446e-5
GO:0032094	response to food	1.204003e-5
GO:0048545	response to steroid hormone stimulus	1.208755e-5
GO:0043503	skeletal muscle fiber adaptation	1.227462e-5
GO:0071417	cellular response to organic nitrogen	1.252455e-5
GO:0033326	cerebrospinal fluid secretion	1.295437e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.303616e-5
GO:0051259	protein oligomerization	1.541422e-5
GO:0009264	deoxyribonucleotide catabolic process	1.599469e-5
GO:0031064	negative regulation of histone deacetylation	1.697129e-5
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	1.859758e-5
GO:0010269	response to selenium ion	1.862189e-5
GO:0034379	very-low-density lipoprotein particle assembly	1.946301e-5
GO:0065002	intracellular protein transmembrane transport	2.023320e-5
GO:0006298	mismatch repair	2.055948e-5
GO:0002019	regulation of renal output by angiotensin	2.098924e-5
GO:0071295	cellular response to vitamin	2.121632e-5
GO:0002604	regulation of dendritic cell antigen processing and presentation	2.151703e-5
GO:0051591	response to cAMP	2.205375e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.360964e-5
GO:0042396	phosphagen biosynthetic process	2.463537e-5
GO:0007520	myoblast fusion	2.521437e-5
GO:0043001	Golgi to plasma membrane protein transport	2.560318e-5
GO:0071418	cellular response to amine stimulus	2.570628e-5
GO:0015879	carnitine transport	2.572124e-5
GO:0044241	lipid digestion	2.660274e-5
GO:0014902	myotube differentiation	2.671341e-5
GO:0008203	cholesterol metabolic process	2.943748e-5
GO:0006002	fructose 6-phosphate metabolic process	2.973026e-5
GO:0044240	multicellular organismal lipid catabolic process	2.986831e-5
GO:0031960	response to corticosteroid stimulus	3.071485e-5
GO:0006694	steroid biosynthetic process	3.102280e-5
GO:0050685	positive regulation of mRNA processing	3.185066e-5
GO:0008033	tRNA processing	3.187479e-5
GO:0072044	collecting duct development	3.304915e-5
GO:0046731	passive induction of host immune response by virus	3.322751e-5
GO:0001839	neural plate morphogenesis	3.427871e-5
GO:0034227	tRNA thio-modification	3.448590e-5
GO:0002098	tRNA wobble uridine modification	3.448590e-5
GO:0018293	protein-FAD linkage	4.054412e-5
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	4.054412e-5
GO:0007127	meiosis I	4.184931e-5
GO:0033605	positive regulation of catecholamine secretion	4.244084e-5
GO:0021516	dorsal spinal cord development	4.396937e-5
GO:0002740	negative regulation of cytokine secretion involved in immune response	4.406311e-5
GO:0060621	negative regulation of cholesterol import	4.455061e-5
GO:0044058	regulation of digestive system process	4.633764e-5
GO:0060620	regulation of cholesterol import	4.673993e-5
GO:0061014	positive regulation of mRNA catabolic process	4.787593e-5
GO:0033700	phospholipid efflux	4.950767e-5
GO:0001560	regulation of cell growth by extracellular stimulus	4.956705e-5
GO:0030917	midbrain-hindbrain boundary development	5.137338e-5
GO:0043000	Golgi to plasma membrane CFTR protein transport	5.153278e-5
GO:0070301	cellular response to hydrogen peroxide	5.239920e-5
GO:0035966	response to topologically incorrect protein	5.464034e-5
GO:0021527	spinal cord association neuron differentiation	5.730998e-5
GO:0035914	skeletal muscle cell differentiation	5.804425e-5
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	5.972774e-5
GO:0042407	cristae formation	5.972774e-5
GO:0035726	common myeloid progenitor cell proliferation	5.972774e-5
GO:0035732	nitric oxide storage	5.972774e-5
GO:0060192	negative regulation of lipase activity	5.975800e-5
GO:0001522	pseudouridine synthesis	6.019755e-5
GO:0071230	cellular response to amino acid stimulus	6.069255e-5
GO:0034369	plasma lipoprotein particle remodeling	6.160079e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	6.325947e-5
GO:0006022	aminoglycan metabolic process	6.422973e-5
GO:0030157	pancreatic juice secretion	6.684622e-5
GO:0045046	protein import into peroxisome membrane	7.067937e-5
GO:0042157	lipoprotein metabolic process	9.081729e-5
GO:0051085	chaperone mediated protein folding requiring cofactor	9.228684e-5
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	9.240152e-5
GO:0010985	negative regulation of lipoprotein particle clearance	9.443022e-5
GO:0070574	cadmium ion transmembrane transport	9.701166e-5
GO:0051084	'de novo' posttranslational protein folding	9.936568e-5
GO:0030719	P granule organization	9.971851e-5
GO:0046426	negative regulation of JAK-STAT cascade	1.002226e-4
GO:0045988	negative regulation of striated muscle contraction	1.002226e-4
GO:0010735	positive regulation of transcription via serum response element binding	1.026352e-4
GO:0030262	apoptotic nuclear change	1.041813e-4
GO:0000303	response to superoxide	1.085172e-4
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1.087272e-4
GO:0044236	multicellular organismal metabolic process	1.105812e-4
GO:0042048	olfactory behavior	1.113680e-4
GO:0060611	mammary gland fat development	1.146904e-4
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	1.186602e-4
GO:0006400	tRNA modification	1.199092e-4
GO:0034377	plasma lipoprotein particle assembly	1.218344e-4
GO:0002577	regulation of antigen processing and presentation	1.225454e-4
GO:0008610	lipid biosynthetic process	1.231723e-4
GO:0051289	protein homotetramerization	1.249118e-4
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	1.325223e-4
GO:0007509	mesoderm migration involved in gastrulation	1.351068e-4
GO:0032963	collagen metabolic process	1.354864e-4
GO:0060419	heart growth	1.420136e-4
GO:0019430	removal of superoxide radicals	1.420877e-4
GO:0015670	carbon dioxide transport	1.422873e-4
GO:0006399	tRNA metabolic process	1.462308e-4
GO:0035799	ureter maturation	1.482050e-4
GO:2000597	positive regulation of optic nerve formation	1.482050e-4
GO:0061360	optic chiasma development	1.482050e-4
GO:0021650	vestibulocochlear nerve formation	1.482050e-4
GO:0021633	optic nerve structural organization	1.482050e-4
GO:0031081	nuclear pore distribution	1.497100e-4
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.503937e-4
GO:0007021	tubulin complex assembly	1.523265e-4
GO:0002017	regulation of blood volume by renal aldosterone	1.548127e-4
GO:0001840	neural plate development	1.548725e-4
GO:0006986	response to unfolded protein	1.644027e-4
GO:0045112	integrin biosynthetic process	1.657968e-4
GO:0045109	intermediate filament organization	1.659142e-4
GO:0009262	deoxyribonucleotide metabolic process	1.684651e-4
GO:0010544	negative regulation of platelet activation	1.696549e-4
GO:0006285	base-excision repair, AP site formation	1.732069e-4
GO:0070228	regulation of lymphocyte apoptosis	1.747154e-4
GO:0007141	male meiosis I	1.750459e-4
GO:0007398	ectoderm development	1.791341e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.803810e-4
GO:0002902	regulation of B cell apoptosis	1.810298e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.822475e-4
GO:0045618	positive regulation of keratinocyte differentiation	1.932363e-4
GO:0043588	skin development	1.940970e-4
GO:0006625	protein targeting to peroxisome	1.952597e-4
GO:0070375	BMK cascade	2.028249e-4
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	2.041008e-4
GO:0044259	multicellular organismal macromolecule metabolic process	2.060599e-4
GO:0045918	negative regulation of cytolysis	2.067620e-4
GO:0019264	glycine biosynthetic process from serine	2.067620e-4
GO:0009225	nucleotide-sugar metabolic process	2.090153e-4
GO:0060346	bone trabecula formation	2.090153e-4
GO:0007635	chemosensory behavior	2.147432e-4
GO:0000305	response to oxygen radical	2.155369e-4
GO:0031440	regulation of mRNA 3'-end processing	2.202578e-4
GO:0045746	negative regulation of Notch signaling pathway	2.210716e-4
GO:0033625	positive regulation of integrin activation	2.244715e-4
GO:0071385	cellular response to glucocorticoid stimulus	2.259450e-4
GO:0031670	cellular response to nutrient	2.264840e-4
GO:0071229	cellular response to acid	2.450053e-4
GO:0008202	steroid metabolic process	2.505554e-4
GO:0051293	establishment of spindle localization	2.595982e-4
GO:0060482	lobar bronchus development	2.631993e-4
GO:0016052	carbohydrate catabolic process	2.657755e-4
GO:0006855	drug transmembrane transport	2.737152e-4
GO:0001957	intramembranous ossification	2.829969e-4
GO:0048627	myoblast development	2.929411e-4
GO:0046069	cGMP catabolic process	2.966010e-4
GO:0034614	cellular response to reactive oxygen species	3.017904e-4
GO:0061025	membrane fusion	3.156908e-4
GO:0045651	positive regulation of macrophage differentiation	3.249312e-4
GO:0045657	positive regulation of monocyte differentiation	3.249312e-4
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	3.268654e-4
GO:0045454	cell redox homeostasis	3.486940e-4
GO:0005976	polysaccharide metabolic process	3.507887e-4
GO:0006853	carnitine shuttle	3.561831e-4
GO:0072593	reactive oxygen species metabolic process	3.610075e-4
GO:0006308	DNA catabolic process	3.638757e-4
GO:0045655	regulation of monocyte differentiation	3.653964e-4
GO:0006942	regulation of striated muscle contraction	3.723218e-4
GO:0051262	protein tetramerization	3.728272e-4
GO:0006560	proline metabolic process	3.745420e-4
GO:0006944	cellular membrane fusion	3.764082e-4
GO:0045007	depurination	3.770136e-4
GO:0097006	regulation of plasma lipoprotein particle levels	3.787103e-4
GO:0043574	peroxisomal transport	3.877693e-4
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	3.936175e-4
GO:0061049	cell growth involved in cardiac muscle cell development	3.936175e-4
GO:0003331	positive regulation of extracellular matrix constituent secretion	3.936175e-4
GO:0002508	central tolerance induction	3.936175e-4
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	3.936175e-4
GO:0002897	positive regulation of central B cell tolerance induction	3.936175e-4
GO:0046394	carboxylic acid biosynthetic process	3.960515e-4
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	3.971844e-4
GO:0034374	low-density lipoprotein particle remodeling	4.016377e-4
GO:0002115	store-operated calcium entry	4.122068e-4
GO:2000242	negative regulation of reproductive process	4.134063e-4
GO:0006458	'de novo' protein folding	4.152567e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	4.171953e-4
GO:0006438	valyl-tRNA aminoacylation	4.220439e-4
GO:0010596	negative regulation of endothelial cell migration	4.340394e-4
GO:0048664	neuron fate determination	4.393828e-4
GO:0043060	meiotic metaphase I plate congression	4.449969e-4
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	4.493586e-4
GO:2000106	regulation of leukocyte apoptosis	4.563856e-4
GO:0090257	regulation of muscle system process	4.655025e-4
GO:0000272	polysaccharide catabolic process	4.730486e-4
GO:0021575	hindbrain morphogenesis	4.751112e-4
GO:0014014	negative regulation of gliogenesis	4.782484e-4
GO:0016126	sterol biosynthetic process	4.830175e-4
GO:0021998	neural plate mediolateral regionalization	5.005590e-4
GO:0048352	paraxial mesoderm structural organization	5.005590e-4
GO:0042723	thiamine-containing compound metabolic process	5.110021e-4
GO:0006949	syncytium formation	5.114390e-4
GO:0021555	midbrain-hindbrain boundary morphogenesis	5.145580e-4
GO:0031119	tRNA pseudouridine synthesis	5.190550e-4
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	5.190550e-4
GO:0051567	histone H3-K9 methylation	5.198488e-4
GO:0001880	Mullerian duct regression	5.415658e-4
GO:0033159	negative regulation of protein import into nucleus, translocation	5.415658e-4
GO:0042703	menstruation	5.434190e-4
GO:0019101	female somatic sex determination	5.434190e-4
GO:0003406	retinal pigment epithelium development	5.434190e-4
GO:0070344	regulation of fat cell proliferation	5.562538e-4
GO:0015695	organic cation transport	5.762844e-4
GO:0051346	negative regulation of hydrolase activity	5.779964e-4
GO:0021903	rostrocaudal neural tube patterning	5.877411e-4
GO:0032506	cytokinetic process	5.905039e-4
GO:0044154	histone H3-K14 acetylation	5.929726e-4
GO:0035511	oxidative DNA demethylation	5.941859e-4
GO:0001977	renal system process involved in regulation of blood volume	5.993623e-4
GO:0045047	protein targeting to ER	6.043980e-4
GO:0070734	histone H3-K27 methylation	6.070298e-4
GO:0048382	mesendoderm development	6.070298e-4
GO:0055017	cardiac muscle tissue growth	6.210717e-4
GO:0097150	neuronal stem cell maintenance	6.232503e-4
GO:0001955	blood vessel maturation	6.272815e-4
GO:0051303	establishment of chromosome localization	6.285458e-4
GO:0010960	magnesium ion homeostasis	6.439570e-4
GO:0009069	serine family amino acid metabolic process	6.468985e-4
GO:0031268	pseudopodium organization	6.610955e-4
GO:0021528	commissural neuron differentiation in spinal cord	6.610955e-4
GO:0032355	response to estradiol stimulus	6.621964e-4
GO:0042168	heme metabolic process	6.890404e-4
GO:0071356	cellular response to tumor necrosis factor	6.952342e-4
GO:0006065	UDP-glucuronate biosynthetic process	6.955481e-4
GO:2000974	negative regulation of pro-B cell differentiation	6.960414e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	7.260124e-4
GO:0003105	negative regulation of glomerular filtration	7.783522e-4
GO:0000093	mitotic telophase	7.934392e-4
GO:0006551	leucine metabolic process	8.208524e-4
GO:0010721	negative regulation of cell development	8.323305e-4
GO:0006633	fatty acid biosynthetic process	8.331074e-4
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	8.409956e-4
GO:0023035	CD40 signaling pathway	8.409956e-4
GO:0008049	male courtship behavior	8.409956e-4
GO:0022007	convergent extension involved in neural plate elongation	8.573714e-4
GO:0071383	cellular response to steroid hormone stimulus	8.656797e-4
GO:0046340	diacylglycerol catabolic process	8.696041e-4
GO:0097039	protein linear polyubiquitination	8.699855e-4
GO:0070849	response to epidermal growth factor stimulus	8.768672e-4
GO:0002830	positive regulation of type 2 immune response	8.769142e-4
GO:0000271	polysaccharide biosynthetic process	8.786881e-4
GO:0002066	columnar/cuboidal epithelial cell development	8.945041e-4
GO:2000737	negative regulation of stem cell differentiation	8.949470e-4
GO:0009303	rRNA transcription	9.130450e-4
GO:0042661	regulation of mesodermal cell fate specification	9.359211e-4
GO:0043534	blood vessel endothelial cell migration	9.608909e-4
GO:0006857	oligopeptide transport	9.774151e-4
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	9.774480e-4
GO:0043248	proteasome assembly	1.013863e-3
GO:0016557	peroxisome membrane biogenesis	1.023890e-3
GO:0042354	L-fucose metabolic process	1.032527e-3
GO:0030203	glycosaminoglycan metabolic process	1.056209e-3
GO:2000210	positive regulation of anoikis	1.062033e-3
GO:0006561	proline biosynthetic process	1.062033e-3
GO:2000380	regulation of mesoderm development	1.067602e-3
GO:0051952	regulation of amine transport	1.077066e-3
GO:0071460	cellular response to cell-matrix adhesion	1.099602e-3
GO:0071335	hair follicle cell proliferation	1.117937e-3
GO:0032290	peripheral nervous system myelin formation	1.117937e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	1.144135e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	1.155344e-3
GO:0035845	photoreceptor cell outer segment organization	1.155344e-3
GO:0035545	determination of left/right asymmetry in nervous system	1.155344e-3
GO:0032902	nerve growth factor production	1.200581e-3
GO:0032057	negative regulation of translational initiation in response to stress	1.204041e-3
GO:0035814	negative regulation of renal sodium excretion	1.206410e-3
GO:0051220	cytoplasmic sequestering of protein	1.236330e-3
GO:0014037	Schwann cell differentiation	1.236330e-3
GO:0030225	macrophage differentiation	1.246152e-3
GO:0035090	maintenance of apical/basal cell polarity	1.251668e-3
GO:0021587	cerebellum morphogenesis	1.254616e-3
GO:0032606	type I interferon production	1.258486e-3
GO:0030185	nitric oxide transport	1.262168e-3
GO:0007162	negative regulation of cell adhesion	1.267079e-3
GO:0030004	cellular monovalent inorganic cation homeostasis	1.270902e-3
GO:0006370	mRNA capping	1.276158e-3
GO:0009308	amine metabolic process	1.286152e-3
GO:0007128	meiotic prophase I	1.310527e-3
GO:0046339	diacylglycerol metabolic process	1.331876e-3
GO:0048144	fibroblast proliferation	1.358838e-3
GO:0001516	prostaglandin biosynthetic process	1.384183e-3
GO:0006636	unsaturated fatty acid biosynthetic process	1.418325e-3
GO:0008078	mesodermal cell migration	1.464266e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	1.499425e-3
GO:0007217	tachykinin receptor signaling pathway	1.524429e-3
GO:0009452	RNA capping	1.527889e-3
GO:0042074	cell migration involved in gastrulation	1.560099e-3
GO:0000726	non-recombinational repair	1.568471e-3
GO:0009589	detection of UV	1.581168e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.581168e-3
GO:0002554	serotonin secretion by platelet	1.581168e-3
GO:0002522	leukocyte migration involved in immune response	1.581168e-3
GO:0050771	negative regulation of axonogenesis	1.590325e-3
GO:0070926	regulation of ATP:ADP antiporter activity	1.604233e-3
GO:0008065	establishment of blood-nerve barrier	1.604233e-3
GO:0002071	glandular epithelial cell maturation	1.604233e-3
GO:0042117	monocyte activation	1.605754e-3
GO:0031668	cellular response to extracellular stimulus	1.609594e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.624180e-3
GO:0031282	regulation of guanylate cyclase activity	1.648975e-3
GO:0046877	regulation of saliva secretion	1.648975e-3
GO:0050779	RNA destabilization	1.660105e-3
GO:0009103	lipopolysaccharide biosynthetic process	1.664602e-3
GO:0002676	regulation of chronic inflammatory response	1.664602e-3
GO:0006481	C-terminal protein methylation	1.664677e-3
GO:0051764	actin crosslink formation	1.688588e-3
GO:0042159	lipoprotein catabolic process	1.700353e-3
GO:0045919	positive regulation of cytolysis	1.708145e-3
GO:0042552	myelination	1.729805e-3
GO:0045110	intermediate filament bundle assembly	1.739850e-3
GO:0060179	male mating behavior	1.747488e-3
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.747488e-3
GO:0010939	regulation of necrotic cell death	1.751455e-3
GO:0045342	MHC class II biosynthetic process	1.789607e-3
GO:0070839	divalent metal ion export	1.789607e-3
GO:0043091	L-arginine import	1.789607e-3
GO:0015707	nitrite transport	1.789607e-3
GO:0006876	cellular cadmium ion homeostasis	1.789607e-3
GO:0032632	interleukin-3 production	1.789607e-3
GO:0035767	endothelial cell chemotaxis	1.794847e-3
GO:0051588	regulation of neurotransmitter transport	1.806239e-3
GO:0070988	demethylation	1.811343e-3
GO:0007031	peroxisome organization	1.865042e-3
GO:0072668	tubulin complex biogenesis	1.869038e-3
GO:0072321	chaperone-mediated protein transport	1.875118e-3
GO:0060282	positive regulation of oocyte development	1.883974e-3
GO:0009071	serine family amino acid catabolic process	1.945556e-3
GO:0000387	spliceosomal snRNP assembly	1.949131e-3
GO:0008355	olfactory learning	1.968472e-3
GO:0002443	leukocyte mediated immunity	1.970090e-3
GO:0034384	high-density lipoprotein particle clearance	1.988152e-3
GO:0048477	oogenesis	1.992645e-3
GO:0035089	establishment of apical/basal cell polarity	1.994283e-3
GO:0050832	defense response to fungus	2.001048e-3
GO:0000002	mitochondrial genome maintenance	2.013957e-3
GO:0060555	induction of necroptosis by extracellular signals	2.015548e-3
GO:0006546	glycine catabolic process	2.038607e-3
GO:0006091	generation of precursor metabolites and energy	2.052700e-3
GO:0006066	alcohol metabolic process	2.058725e-3
GO:0023019	signal transduction involved in regulation of gene expression	2.063181e-3
GO:0034104	negative regulation of tissue remodeling	2.108404e-3
GO:0046185	aldehyde catabolic process	2.122319e-3
GO:0060911	cardiac cell fate commitment	2.131398e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.163164e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2.201110e-3
GO:0070417	cellular response to cold	2.204177e-3
GO:0044283	small molecule biosynthetic process	2.211082e-3
GO:0001958	endochondral ossification	2.224115e-3
GO:0060920	pacemaker cell differentiation	2.240543e-3
GO:0030221	basophil differentiation	2.240543e-3
GO:0010897	negative regulation of triglyceride catabolic process	2.240543e-3
GO:0030213	hyaluronan biosynthetic process	2.240543e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.240543e-3
GO:0060691	epithelial cell maturation involved in salivary gland development	2.297934e-3
GO:0060096	serotonin secretion, neurotransmission	2.297934e-3
GO:0000239	pachytene	2.317486e-3
GO:0051532	regulation of NFAT protein import into nucleus	2.325498e-3
GO:0045606	positive regulation of epidermal cell differentiation	2.351580e-3
GO:0010830	regulation of myotube differentiation	2.376415e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	2.427260e-3
GO:0007518	myoblast cell fate determination	2.427260e-3
GO:0030037	actin filament reorganization involved in cell cycle	2.429984e-3
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.509770e-3
GO:0048242	epinephrine secretion	2.540764e-3
GO:0072205	metanephric collecting duct development	2.543204e-3
GO:0055067	monovalent inorganic cation homeostasis	2.548405e-3
GO:0050433	regulation of catecholamine secretion	2.556745e-3
GO:0046878	positive regulation of saliva secretion	2.568747e-3
GO:0002074	extraocular skeletal muscle development	2.568747e-3
GO:0061009	common bile duct development	2.569431e-3
GO:0006307	DNA dealkylation involved in DNA repair	2.569431e-3
GO:0035566	regulation of metanephros size	2.599968e-3
GO:0016081	synaptic vesicle docking involved in exocytosis	2.604458e-3
GO:0070305	response to cGMP	2.604709e-3
GO:0007589	body fluid secretion	2.626294e-3
GO:0030220	platelet formation	2.634481e-3
GO:0006457	protein folding	2.639618e-3
GO:0006892	post-Golgi vesicle-mediated transport	2.646971e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.687073e-3
GO:0008594	photoreceptor cell morphogenesis	2.702999e-3
GO:0042304	regulation of fatty acid biosynthetic process	2.740669e-3
GO:0043589	skin morphogenesis	2.742187e-3
GO:0035036	sperm-egg recognition	2.747146e-3
GO:0048147	negative regulation of fibroblast proliferation	2.818361e-3
GO:0018146	keratan sulfate biosynthetic process	2.819672e-3
GO:0015893	drug transport	2.822096e-3
GO:0042593	glucose homeostasis	2.848013e-3
GO:0006023	aminoglycan biosynthetic process	2.848274e-3
GO:0071321	cellular response to cGMP	2.848685e-3
GO:0071585	detoxification of cadmium ion	2.866484e-3
GO:0034224	cellular response to zinc ion starvation	2.866484e-3
GO:0034120	positive regulation of erythrocyte aggregation	2.866484e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	2.979965e-3
GO:0006011	UDP-glucose metabolic process	2.979965e-3
GO:0014029	neural crest formation	2.998944e-3
GO:0006657	CDP-choline pathway	3.009293e-3
GO:0001707	mesoderm formation	3.018267e-3
GO:0042891	antibiotic transport	3.018761e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0003158	endothelium development	1.458311e-9
GO:0045446	endothelial cell differentiation	2.115551e-9
GO:0035966	response to topologically incorrect protein	1.125364e-8
GO:0045796	negative regulation of intestinal cholesterol absorption	3.214874e-8
GO:0010949	negative regulation of intestinal phytosterol absorption	3.214874e-8
GO:0045920	negative regulation of exocytosis	4.049091e-8
GO:0035691	macrophage migration inhibitory factor signaling pathway	4.738862e-8
GO:0001885	endothelial cell development	7.608635e-8
GO:0051085	chaperone mediated protein folding requiring cofactor	8.199762e-8
GO:0061077	chaperone-mediated protein folding	1.939151e-7
GO:0045578	negative regulation of B cell differentiation	2.259766e-7
GO:0046325	negative regulation of glucose import	2.489167e-7
GO:0010829	negative regulation of glucose transport	3.301759e-7
GO:0032456	endocytic recycling	5.473981e-7
GO:0044062	regulation of excretion	7.585927e-7
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	8.686097e-7
GO:0035813	regulation of renal sodium excretion	9.158583e-7
GO:0060457	negative regulation of digestive system process	9.309721e-7
GO:0018209	peptidyl-serine modification	1.154266e-6
GO:0006986	response to unfolded protein	1.515029e-6
GO:0051084	'de novo' posttranslational protein folding	1.941529e-6
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.943610e-6
GO:0051532	regulation of NFAT protein import into nucleus	2.121708e-6
GO:0035967	cellular response to topologically incorrect protein	2.132495e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	2.520392e-6
GO:2000271	positive regulation of fibroblast apoptosis	2.936083e-6
GO:0030042	actin filament depolymerization	2.936083e-6
GO:2000270	negative regulation of fibroblast apoptosis	2.936083e-6
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	2.936083e-6
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	2.936083e-6
GO:0043301	negative regulation of leukocyte degranulation	3.096223e-6
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	3.160719e-6
GO:0016090	prenol metabolic process	3.327350e-6
GO:0042274	ribosomal small subunit biogenesis	3.431704e-6
GO:0034968	histone lysine methylation	4.367304e-6
GO:0045955	negative regulation of calcium ion-dependent exocytosis	4.686860e-6
GO:0035814	negative regulation of renal sodium excretion	5.266209e-6
GO:0045606	positive regulation of epidermal cell differentiation	5.881440e-6
GO:0045618	positive regulation of keratinocyte differentiation	6.270077e-6
GO:0060327	cytoplasmic actin-based contraction involved in cell motility	6.617064e-6
GO:2000392	regulation of lamellipodium morphogenesis	6.617064e-6
GO:0046949	fatty-acyl-CoA biosynthetic process	6.617064e-6
GO:0051048	negative regulation of secretion	6.913987e-6
GO:0061028	establishment of endothelial barrier	7.099020e-6
GO:0022009	central nervous system vasculogenesis	7.331569e-6
GO:0032682	negative regulation of chemokine production	7.763867e-6
GO:0051261	protein depolymerization	8.005286e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	8.334707e-6
GO:0018105	peptidyl-serine phosphorylation	9.101607e-6
GO:0048384	retinoic acid receptor signaling pathway	9.109008e-6
GO:0071380	cellular response to prostaglandin E stimulus	9.655370e-6
GO:0016571	histone methylation	1.031815e-5
GO:0045684	positive regulation of epidermis development	1.097549e-5
GO:0071218	cellular response to misfolded protein	1.106215e-5
GO:0051533	positive regulation of NFAT protein import into nucleus	1.106215e-5
GO:0018022	peptidyl-lysine methylation	1.152123e-5
GO:0072061	inner medullary collecting duct development	1.207600e-5
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.207600e-5
GO:0072060	outer medullary collecting duct development	1.207600e-5
GO:0002268	follicular dendritic cell differentiation	1.481331e-5
GO:0018023	peptidyl-lysine trimethylation	1.520771e-5
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.697968e-5
GO:0030490	maturation of SSU-rRNA	1.726240e-5
GO:0090023	positive regulation of neutrophil chemotaxis	1.952022e-5
GO:0051051	negative regulation of transport	2.001107e-5
GO:0060461	right lung morphogenesis	2.464356e-5
GO:0090131	mesenchyme migration	2.464356e-5
GO:0060446	branching involved in open tracheal system development	2.464356e-5
GO:0048371	lateral mesodermal cell differentiation	2.464356e-5
GO:0048613	embryonic ectodermal digestive tract morphogenesis	2.464356e-5
GO:0014822	detection of wounding	2.464356e-5
GO:0060482	lobar bronchus development	2.515513e-5
GO:0006360	transcription from RNA polymerase I promoter	3.179229e-5
GO:0031999	negative regulation of fatty acid beta-oxidation	3.260172e-5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	3.534583e-5
GO:0048566	embryonic digestive tract development	3.738601e-5
GO:0061038	uterus morphogenesis	3.864734e-5
GO:0043314	negative regulation of neutrophil degranulation	4.024759e-5
GO:0060218	hemopoietic stem cell differentiation	4.024759e-5
GO:0060669	embryonic placenta morphogenesis	4.236451e-5
GO:0016082	synaptic vesicle priming	4.862195e-5
GO:0060708	spongiotrophoblast differentiation	4.935397e-5
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	5.031059e-5
GO:0051014	actin filament severing	5.031059e-5
GO:0045575	basophil activation	5.273955e-5
GO:0034651	cortisol biosynthetic process	5.273955e-5
GO:0035865	cellular response to potassium ion	5.273955e-5
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	5.302869e-5
GO:0014719	satellite cell activation	5.302869e-5
GO:0072044	collecting duct development	5.455766e-5
GO:0032692	negative regulation of interleukin-1 production	5.539595e-5
GO:0060555	induction of necroptosis by extracellular signals	5.706736e-5
GO:0032930	positive regulation of superoxide anion generation	5.706736e-5
GO:0032928	regulation of superoxide anion generation	5.958902e-5
GO:0060712	spongiotrophoblast layer development	6.432473e-5
GO:0072095	regulation of branch elongation involved in ureteric bud branching	6.764939e-5
GO:0017158	regulation of calcium ion-dependent exocytosis	6.815505e-5
GO:0016074	snoRNA metabolic process	6.911624e-5
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	7.633631e-5
GO:0035269	protein O-linked mannosylation	8.013832e-5
GO:0002328	pro-B cell differentiation	9.031908e-5
GO:0044058	regulation of digestive system process	1.010859e-4
GO:0060709	glycogen cell development involved in embryonic placenta development	1.042066e-4
GO:0032342	aldosterone biosynthetic process	1.042066e-4
GO:0072181	mesonephric duct formation	1.128523e-4
GO:0001555	oocyte growth	1.128523e-4
GO:0072172	mesonephric tubule formation	1.162256e-4
GO:0071299	cellular response to vitamin A	1.177018e-4
GO:0002036	regulation of L-glutamate transport	1.240670e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.260808e-4
GO:0014045	establishment of endothelial blood-brain barrier	1.260808e-4
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.451942e-4
GO:0045948	positive regulation of translational initiation	1.462372e-4
GO:0032691	negative regulation of interleukin-1 beta production	1.552515e-4
GO:0017157	regulation of exocytosis	1.606210e-4
GO:0006546	glycine catabolic process	1.618550e-4
GO:0006417	regulation of translation	1.636008e-4
GO:0023019	signal transduction involved in regulation of gene expression	1.694969e-4
GO:0072205	metanephric collecting duct development	1.701842e-4
GO:0071773	cellular response to BMP stimulus	1.897949e-4
GO:0045835	negative regulation of meiosis	1.897949e-4
GO:0009956	radial pattern formation	1.897949e-4
GO:2000429	negative regulation of neutrophil aggregation	2.154242e-4
GO:2000469	negative regulation of peroxidase activity	2.154242e-4
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	2.154242e-4
GO:0035726	common myeloid progenitor cell proliferation	2.154242e-4
GO:0002561	basophil degranulation	2.154242e-4
GO:0021528	commissural neuron differentiation in spinal cord	2.154242e-4
GO:0048227	plasma membrane to endosome transport	2.154242e-4
GO:0002830	positive regulation of type 2 immune response	2.174301e-4
GO:0071300	cellular response to retinoic acid	2.230622e-4
GO:0032536	regulation of cell projection size	2.305453e-4
GO:0090022	regulation of neutrophil chemotaxis	2.426169e-4
GO:0006927	transformed cell apoptosis	2.438103e-4
GO:0035729	cellular response to hepatocyte growth factor stimulus	2.841600e-4
GO:0016064	immunoglobulin mediated immune response	2.918677e-4
GO:0035565	regulation of pronephros size	2.974175e-4
GO:0039020	pronephric nephron tubule development	2.974175e-4
GO:0003329	pancreatic PP cell fate commitment	2.974175e-4
GO:0003326	pancreatic A cell fate commitment	2.974175e-4
GO:0055123	digestive system development	2.999327e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	3.303867e-4
GO:0001552	ovarian follicle atresia	3.315380e-4
GO:0019428	allantoin biosynthetic process	3.315380e-4
GO:0006098	pentose-phosphate shunt	3.463664e-4
GO:0071845	cellular component disassembly at cellular level	3.521273e-4
GO:0019724	B cell mediated immunity	3.523989e-4
GO:0010939	regulation of necrotic cell death	3.545735e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	3.785817e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.815591e-4
GO:0048388	endosomal lumen acidification	3.857252e-4
GO:0007163	establishment or maintenance of cell polarity	3.913039e-4
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	4.039057e-4
GO:0060430	lung saccule development	4.065377e-4
GO:0072164	mesonephric tubule development	4.102228e-4
GO:0001823	mesonephros development	4.114869e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	4.151251e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	4.151251e-4
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	4.155007e-4
GO:0007028	cytoplasm organization	4.155007e-4
GO:0018216	peptidyl-arginine methylation	4.231833e-4
GO:0045006	DNA deamination	4.271419e-4
GO:0018195	peptidyl-arginine modification	4.378296e-4
GO:0060428	lung epithelium development	4.612225e-4
GO:0060993	kidney morphogenesis	5.001552e-4
GO:0034380	high-density lipoprotein particle assembly	5.105185e-4
GO:0002642	positive regulation of immunoglobulin biosynthetic process	5.150247e-4
GO:0019348	dolichol metabolic process	5.310272e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	5.310272e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	5.413810e-4
GO:0070141	response to UV-A	5.522912e-4
GO:0018198	peptidyl-cysteine modification	5.522912e-4
GO:0001893	maternal placenta development	5.558501e-4
GO:0032770	positive regulation of monooxygenase activity	5.560228e-4
GO:0031133	regulation of axon diameter	5.684507e-4
GO:0035246	peptidyl-arginine N-methylation	5.729679e-4
GO:0007029	endoplasmic reticulum organization	5.779077e-4
GO:0022411	cellular component disassembly	6.003682e-4
GO:0014807	regulation of somitogenesis	6.392196e-4
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	6.392196e-4
GO:0051788	response to misfolded protein	6.663603e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	6.663603e-4
GO:0030968	endoplasmic reticulum unfolded protein response	6.674291e-4
GO:2000146	negative regulation of cell motility	6.792597e-4
GO:0032488	Cdc42 protein signal transduction	6.871390e-4
GO:0019673	GDP-mannose metabolic process	7.361381e-4
GO:0002443	leukocyte mediated immunity	7.364778e-4
GO:0030336	negative regulation of cell migration	7.472733e-4
GO:0003310	pancreatic A cell differentiation	7.611581e-4
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	7.628970e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	7.641493e-4
GO:0045994	positive regulation of translational initiation by iron	7.641493e-4
GO:0002037	negative regulation of L-glutamate transport	7.641493e-4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	7.641493e-4
GO:0043313	regulation of neutrophil degranulation	7.796624e-4
GO:0033504	floor plate development	8.199701e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	8.306494e-4
GO:0046185	aldehyde catabolic process	8.392919e-4
GO:0034637	cellular carbohydrate biosynthetic process	8.721668e-4
GO:0060010	Sertoli cell fate commitment	8.856537e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	8.856537e-4
GO:0030730	sequestering of triglyceride	8.901261e-4
GO:0006304	DNA modification	9.179730e-4
GO:0045940	positive regulation of steroid metabolic process	9.208687e-4
GO:0090136	epithelial cell-cell adhesion	9.589388e-4
GO:0008625	induction of apoptosis via death domain receptors	9.703369e-4
GO:0003209	cardiac atrium morphogenesis	9.830620e-4
GO:0010940	positive regulation of necrotic cell death	1.023033e-3
GO:0007386	compartment pattern specification	1.023033e-3
GO:0033566	gamma-tubulin complex localization	1.023305e-3
GO:0035881	amacrine cell differentiation	1.031125e-3
GO:0030855	epithelial cell differentiation	1.042311e-3
GO:0072236	metanephric loop of Henle development	1.049131e-3
GO:0034969	histone arginine methylation	1.057007e-3
GO:0050711	negative regulation of interleukin-1 secretion	1.061111e-3
GO:0019884	antigen processing and presentation of exogenous antigen	1.101963e-3
GO:0002098	tRNA wobble uridine modification	1.138243e-3
GO:0051271	negative regulation of cellular component movement	1.164935e-3
GO:0002478	antigen processing and presentation of exogenous peptide antigen	1.167755e-3
GO:0032900	negative regulation of neurotrophin production	1.173718e-3
GO:0032244	positive regulation of nucleoside transport	1.173718e-3
GO:0072171	mesonephric tubule morphogenesis	1.175096e-3
GO:0018202	peptidyl-histidine modification	1.175096e-3
GO:2000781	positive regulation of double-strand break repair	1.191532e-3
GO:0005979	regulation of glycogen biosynthetic process	1.226838e-3
GO:0006479	protein methylation	1.228914e-3
GO:0006796	phosphate-containing compound metabolic process	1.256770e-3
GO:0070873	regulation of glycogen metabolic process	1.336318e-3
GO:0071715	icosanoid transport	1.349209e-3
GO:0003289	atrial septum primum morphogenesis	1.349209e-3
GO:0006572	tyrosine catabolic process	1.365828e-3
GO:0003230	cardiac atrium development	1.382949e-3
GO:0071712	ER-associated misfolded protein catabolic process	1.386458e-3
GO:0060591	chondroblast differentiation	1.405835e-3
GO:0034227	tRNA thio-modification	1.421291e-3
GO:0021915	neural tube development	1.459742e-3
GO:0046889	positive regulation of lipid biosynthetic process	1.517708e-3
GO:0046847	filopodium assembly	1.524024e-3
GO:0014044	Schwann cell development	1.544228e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.573101e-3
GO:0045338	farnesyl diphosphate metabolic process	1.582359e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	1.582359e-3
GO:0045773	positive regulation of axon extension	1.622060e-3
GO:0060713	labyrinthine layer morphogenesis	1.626411e-3
GO:0060033	anatomical structure regression	1.635082e-3
GO:0045123	cellular extravasation	1.636221e-3
GO:0006364	rRNA processing	1.648657e-3
GO:0051568	histone H3-K4 methylation	1.683045e-3
GO:0045727	positive regulation of translation	1.692996e-3
GO:0033505	floor plate morphogenesis	1.706374e-3
GO:0051081	nuclear envelope disassembly	1.711855e-3
GO:0006560	proline metabolic process	1.711855e-3
GO:0050901	leukocyte tethering or rolling	1.727581e-3
GO:0072054	renal outer medulla development	1.811579e-3
GO:0032615	interleukin-12 production	1.811579e-3
GO:0030204	chondroitin sulfate metabolic process	1.851307e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.858104e-3
GO:0007440	foregut morphogenesis	1.877977e-3
GO:0045654	positive regulation of megakaryocyte differentiation	1.884209e-3
GO:0001886	endothelial cell morphogenesis	1.892993e-3
GO:0002064	epithelial cell development	1.894643e-3
GO:0006498	N-terminal protein lipidation	1.908083e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	1.917392e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.932785e-3
GO:0007509	mesoderm migration involved in gastrulation	1.946178e-3
GO:0060606	tube closure	1.953849e-3
GO:0032060	bleb assembly	1.960407e-3
GO:0046322	negative regulation of fatty acid oxidation	1.970049e-3
GO:0001937	negative regulation of endothelial cell proliferation	1.970296e-3
GO:0007412	axon target recognition	1.979708e-3
GO:0001558	regulation of cell growth	2.012159e-3
GO:0007283	spermatogenesis	2.020780e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.065068e-3
GO:0043088	regulation of Cdc42 GTPase activity	2.072464e-3
GO:0045786	negative regulation of cell cycle	2.104183e-3
GO:0034377	plasma lipoprotein particle assembly	2.111652e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	2.111652e-3
GO:0060433	bronchus development	2.154212e-3
GO:0050482	arachidonic acid secretion	2.154212e-3
GO:0016197	endosome transport	2.159970e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	2.203363e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	2.203363e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	2.203363e-3
GO:0035802	adrenal cortex formation	2.203363e-3
GO:0034587	piRNA metabolic process	2.230568e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.263566e-3
GO:0003084	positive regulation of systemic arterial blood pressure	2.270474e-3
GO:0016569	covalent chromatin modification	2.283205e-3
GO:0043624	cellular protein complex disassembly	2.335303e-3
GO:0048147	negative regulation of fibroblast proliferation	2.354244e-3
GO:0032012	regulation of ARF protein signal transduction	2.373178e-3
GO:0043305	negative regulation of mast cell degranulation	2.373395e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.373395e-3
GO:0050766	positive regulation of phagocytosis	2.396939e-3
GO:0008589	regulation of smoothened signaling pathway	2.396939e-3
GO:0046826	negative regulation of protein export from nucleus	2.397690e-3
GO:0090130	tissue migration	2.399888e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.409140e-3
GO:0003338	metanephros morphogenesis	2.451547e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	2.509856e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	2.509856e-3
GO:0006651	diacylglycerol biosynthetic process	2.509856e-3
GO:0015914	phospholipid transport	2.523326e-3
GO:0034623	cellular macromolecular complex disassembly	2.539754e-3
GO:0010224	response to UV-B	2.558462e-3
GO:0051321	meiotic cell cycle	2.602754e-3
GO:0051546	keratinocyte migration	2.637754e-3
GO:0030252	growth hormone secretion	2.637754e-3
GO:0009820	alkaloid metabolic process	2.658569e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	2.672033e-3
GO:0070252	actin-mediated cell contraction	2.673531e-3
GO:0000738	DNA catabolic process, exonucleolytic	2.689475e-3
GO:0006695	cholesterol biosynthetic process	2.713553e-3
GO:0090162	establishment of epithelial cell polarity	2.790331e-3
GO:0042254	ribosome biogenesis	2.837395e-3
GO:0006693	prostaglandin metabolic process	2.931167e-3
GO:0006984	ER-nucleus signaling pathway	2.937018e-3
GO:0071364	cellular response to epidermal growth factor stimulus	2.960893e-3
GO:0030307	positive regulation of cell growth	3.014990e-3
GO:0010893	positive regulation of steroid biosynthetic process	3.016625e-3
GO:0007126	meiosis	3.053091e-3
GO:0002019	regulation of renal output by angiotensin	3.073763e-3
GO:2000065	negative regulation of cortisol biosynthetic process	3.081723e-3
GO:0070194	synaptonemal complex disassembly	3.081723e-3
GO:0032348	negative regulation of aldosterone biosynthetic process	3.081723e-3
GO:0001516	prostaglandin biosynthetic process	3.166873e-3
GO:0016570	histone modification	3.183790e-3
GO:0021707	cerebellar granule cell differentiation	3.195088e-3
GO:0043570	maintenance of DNA repeat elements	3.195088e-3
GO:0016126	sterol biosynthetic process	3.283935e-3
GO:0021508	floor plate formation	3.306223e-3
GO:0071803	positive regulation of podosome assembly	3.310791e-3
GO:0042363	fat-soluble vitamin catabolic process	3.310791e-3
GO:0002347	response to tumor cell	3.310791e-3
GO:0001887	selenium compound metabolic process	3.310791e-3
GO:0006558	L-phenylalanine metabolic process	3.495815e-3
GO:0046324	regulation of glucose import	3.501958e-3
GO:0003382	epithelial cell morphogenesis	3.505531e-3
GO:0071481	cellular response to X-ray	3.573298e-3
GO:0006544	glycine metabolic process	3.577756e-3
GO:0072331	signal transduction by p53 class mediator	3.586937e-3
GO:0033326	cerebrospinal fluid secretion	3.593981e-3
GO:0071217	cellular response to external biotic stimulus	3.593981e-3
GO:0015993	molecular hydrogen transport	3.593981e-3
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	3.599300e-3
GO:0031914	negative regulation of synaptic plasticity	3.599300e-3
GO:0050713	negative regulation of interleukin-1 beta secretion	3.633376e-3
GO:0008078	mesodermal cell migration	3.633376e-3
GO:0045725	positive regulation of glycogen biosynthetic process	3.634031e-3
GO:0016331	morphogenesis of embryonic epithelium	3.634601e-3
GO:0048755	branching morphogenesis of a nerve	3.658796e-3
GO:0043457	regulation of cellular respiration	3.658796e-3
GO:0007549	dosage compensation	3.664483e-3
GO:0002444	myeloid leukocyte mediated immunity	3.684450e-3
GO:0035518	histone H2A monoubiquitination	3.755618e-3
GO:0070086	ubiquitin-dependent endocytosis	3.771514e-3
GO:0051447	negative regulation of meiotic cell cycle	3.771514e-3
GO:0070846	Hsp90 deacetylation	3.771514e-3
GO:0090042	tubulin deacetylation	3.771514e-3
GO:0042840	D-glucuronate catabolic process	3.771514e-3
GO:0002462	tolerance induction to nonself antigen	3.771514e-3
GO:0034776	response to histamine	3.771514e-3
GO:0006419	alanyl-tRNA aminoacylation	3.864064e-3
GO:0042756	drinking behavior	3.866128e-3
GO:0046834	lipid phosphorylation	3.947177e-3
GO:0070875	positive regulation of glycogen metabolic process	4.024565e-3
GO:0030035	microspike assembly	4.189963e-3
GO:0060850	regulation of transcription involved in cell fate commitment	4.199702e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	4.202371e-3
GO:0035039	male pronucleus assembly	4.202371e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	4.202371e-3
GO:0019556	histidine catabolic process to glutamate and formamide	4.202371e-3
GO:0048546	digestive tract morphogenesis	4.260748e-3
GO:0034653	retinoic acid catabolic process	4.297048e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	4.297048e-3
GO:0007422	peripheral nervous system development	4.333106e-3
GO:0072179	nephric duct formation	4.505034e-3
GO:0030010	establishment of cell polarity	4.571676e-3
GO:0060648	mammary gland bud morphogenesis	4.575865e-3
GO:0032873	negative regulation of stress-activated MAPK cascade	4.575865e-3
GO:0070286	axonemal dynein complex assembly	4.616070e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	4.616070e-3
GO:0050995	negative regulation of lipid catabolic process	4.666511e-3
GO:0016072	rRNA metabolic process	4.732272e-3
GO:0034695	response to prostaglandin E stimulus	4.765868e-3
GO:0071295	cellular response to vitamin	4.787012e-3
GO:0060487	lung epithelial cell differentiation	4.835192e-3
GO:0051000	positive regulation of nitric-oxide synthase activity	4.886587e-3
GO:0002031	G-protein coupled receptor internalization	4.938831e-3
GO:0015760	glucose-6-phosphate transport	4.971769e-3
GO:0021683	cerebellar granular layer morphogenesis	4.976770e-3
GO:0006705	mineralocorticoid biosynthetic process	5.038086e-3
GO:0014034	neural crest cell fate commitment	5.038086e-3
GO:0009071	serine family amino acid catabolic process	5.038456e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	5.047604e-3
GO:0046825	regulation of protein export from nucleus	5.233828e-3
GO:0032613	interleukin-10 production	5.417965e-3
GO:0048565	digestive tract development	5.526563e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	5.553979e-3
GO:0002446	neutrophil mediated immunity	5.578218e-3
GO:0070508	cholesterol import	5.618126e-3
GO:0032984	macromolecular complex disassembly	5.635478e-3
GO:0016338	calcium-independent cell-cell adhesion	5.635478e-3
GO:0010596	negative regulation of endothelial cell migration	5.693584e-3
GO:0046626	regulation of insulin receptor signaling pathway	5.699096e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	5.782384e-3
GO:0002320	lymphoid progenitor cell differentiation	5.848752e-3
GO:0060677	ureteric bud elongation	5.919337e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	5.919337e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	6.021755e-3
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	6.021755e-3
GO:0043985	histone H4-R3 methylation	6.021755e-3
GO:0006561	proline biosynthetic process	6.021755e-3
GO:0006311	meiotic gene conversion	6.021755e-3
GO:0001843	neural tube closure	6.074862e-3
GO:0060710	chorio-allantoic fusion	6.124065e-3
GO:0032098	regulation of appetite	6.124065e-3
GO:0070265	necrotic cell death	6.143184e-3
GO:0021515	cell differentiation in spinal cord	6.154625e-3
GO:0070050	neuron homeostasis	6.240389e-3
GO:0030225	macrophage differentiation	6.282285e-3
GO:0007015	actin filament organization	6.326421e-3
GO:0035247	peptidyl-arginine omega-N-methylation	6.353930e-3
GO:0072189	ureter development	6.362119e-3
GO:0001825	blastocyst formation	6.415972e-3
GO:0046853	inositol or phosphatidylinositol phosphorylation	6.448690e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	6.448690e-3
GO:0048295	positive regulation of isotype switching to IgE isotypes	6.448690e-3
GO:0035883	enteroendocrine cell differentiation	6.448690e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	6.448690e-3
GO:0051451	myoblast migration	6.448863e-3
GO:0035441	cell migration involved in vasculogenesis	6.448863e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	6.482093e-3
GO:0033688	regulation of osteoblast proliferation	6.544416e-3
GO:0003215	cardiac right ventricle morphogenesis	6.682235e-3
GO:0002017	regulation of blood volume by renal aldosterone	6.683955e-3
GO:0001834	trophectodermal cell proliferation	6.683955e-3
GO:0002579	positive regulation of antigen processing and presentation	6.689175e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	6.710424e-3
GO:0048148	behavioral response to cocaine	6.710424e-3
GO:0032530	regulation of microvillus organization	6.727189e-3
GO:0006308	DNA catabolic process	6.748207e-3
GO:0043241	protein complex disassembly	6.794990e-3
GO:0002149	hypochlorous acid biosynthetic process	6.839381e-3
GO:0060231	mesenchymal to epithelial transition	6.879202e-3
GO:0060413	atrial septum morphogenesis	6.880067e-3
GO:0007217	tachykinin receptor signaling pathway	6.896856e-3
GO:0060066	oviduct development	6.941300e-3
GO:0006306	DNA methylation	7.079453e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	7.233366e-3
GO:0006213	pyrimidine nucleoside metabolic process	7.343959e-3
GO:0048145	regulation of fibroblast proliferation	7.499076e-3
GO:0060539	diaphragm development	7.542043e-3
GO:0035313	wound healing, spreading of epidermal cells	7.565082e-3
GO:0033689	negative regulation of osteoblast proliferation	7.571718e-3
GO:0060879	semicircular canal fusion	7.619204e-3
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	7.619204e-3
GO:0070075	tear secretion	7.619204e-3
GO:0070352	positive regulation of white fat cell proliferation	7.619204e-3
GO:0060661	submandibular salivary gland formation	7.619204e-3
GO:0061115	lung proximal/distal axis specification	7.619204e-3
GO:0050674	urothelial cell proliferation	7.619204e-3
GO:0050677	positive regulation of urothelial cell proliferation	7.619204e-3
GO:0060436	bronchiole morphogenesis	7.619204e-3
GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	7.619204e-3
GO:0016051	carbohydrate biosynthetic process	7.636254e-3
GO:0060711	labyrinthine layer development	7.713502e-3
GO:0030219	megakaryocyte differentiation	7.752243e-3
GO:0048630	skeletal muscle tissue growth	7.758627e-3
GO:0051764	actin crosslink formation	7.908096e-3
GO:0060046	regulation of acrosome reaction	8.193862e-3
GO:0035564	regulation of kidney size	8.193862e-3
GO:0043278	response to morphine	8.268433e-3
GO:0006471	protein ADP-ribosylation	8.320992e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	8.393028e-3
GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	8.462535e-3
GO:0007140	male meiosis	8.465578e-3
GO:0051125	regulation of actin nucleation	8.553886e-3
GO:0032933	SREBP-mediated signaling pathway	8.580653e-3
GO:0033004	negative regulation of mast cell activation	8.644146e-3
GO:0046364	monosaccharide biosynthetic process	8.667147e-3
GO:0034259	negative regulation of Rho GTPase activity	8.967105e-3
GO:0003108	negative regulation of the force of heart contraction by chemical signal	8.967105e-3
GO:0030719	P granule organization	9.030027e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	9.030027e-3
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	9.030722e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	9.030722e-3
GO:0018120	peptidyl-arginine ADP-ribosylation	9.030722e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	9.030722e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	9.107753e-3
GO:0007182	common-partner SMAD protein phosphorylation	9.107753e-3
GO:0007621	negative regulation of female receptivity	9.112703e-3
GO:0061156	pulmonary artery morphogenesis	9.332166e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.332166e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	9.332166e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	9.357082e-3
GO:0003290	atrial septum secundum morphogenesis	9.373951e-3
GO:0045218	zonula adherens maintenance	9.373951e-3
GO:0006663	platelet activating factor biosynthetic process	9.373951e-3
GO:0045332	phospholipid translocation	9.491129e-3