Novel motif:104

name:	motif104_GTWSGMT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006481	C-terminal protein methylation	4.821052e-11
GO:0034623	cellular macromolecular complex disassembly	1.669208e-10
GO:0043624	cellular protein complex disassembly	2.563193e-10
GO:0032984	macromolecular complex disassembly	3.643667e-10
GO:0007610	behavior	4.419740e-10
GO:0043241	protein complex disassembly	6.316580e-10
GO:0006415	translational termination	1.949691e-9
GO:0007612	learning	5.513619e-9
GO:0007611	learning or memory	1.333687e-8
GO:0050890	cognition	2.048188e-8
GO:0003017	lymph circulation	6.066136e-8
GO:0002769	natural killer cell inhibitory signaling pathway	2.129151e-7
GO:0000278	mitotic cell cycle	2.246796e-7
GO:0045767	regulation of anti-apoptosis	3.234611e-7
GO:0060078	regulation of postsynaptic membrane potential	4.573999e-7
GO:0035330	regulation of hippo signaling cascade	5.955966e-7
GO:0042178	xenobiotic catabolic process	6.581443e-7
GO:0019083	viral transcription	6.788269e-7
GO:0032230	positive regulation of synaptic transmission, GABAergic	9.312748e-7
GO:0045768	positive regulation of anti-apoptosis	1.244751e-6
GO:0045666	positive regulation of neuron differentiation	1.529959e-6
GO:0010713	negative regulation of collagen metabolic process	1.884116e-6
GO:0000216	M/G1 transition of mitotic cell cycle	1.926604e-6
GO:0032966	negative regulation of collagen biosynthetic process	2.054277e-6
GO:0060080	regulation of inhibitory postsynaptic membrane potential	2.350666e-6
GO:0051329	interphase of mitotic cell cycle	2.391798e-6
GO:0045007	depurination	2.642654e-6
GO:0008306	associative learning	3.461592e-6
GO:0072033	renal vesicle formation	3.484507e-6
GO:0043312	neutrophil degranulation	4.125139e-6
GO:0031018	endocrine pancreas development	4.167468e-6
GO:0035270	endocrine system development	4.730839e-6
GO:0051325	interphase	4.762999e-6
GO:0060074	synapse maturation	6.806141e-6
GO:0006955	immune response	7.634640e-6
GO:0006449	regulation of translational termination	7.944784e-6
GO:0072395	signal transduction involved in cell cycle checkpoint	9.556345e-6
GO:0007626	locomotory behavior	1.070212e-5
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.122987e-5
GO:0030534	adult behavior	1.326354e-5
GO:0045190	isotype switching	1.379764e-5
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.404187e-5
GO:0051971	positive regulation of transmission of nerve impulse	1.463686e-5
GO:0071845	cellular component disassembly at cellular level	1.466477e-5
GO:0051224	negative regulation of protein transport	1.632866e-5
GO:0060081	membrane hyperpolarization	1.794224e-5
GO:0051351	positive regulation of ligase activity	1.903996e-5
GO:0022411	cellular component disassembly	1.942245e-5
GO:0030900	forebrain development	2.120600e-5
GO:0072092	ureteric bud invasion	2.261798e-5
GO:0019058	viral infectious cycle	2.959410e-5
GO:0031646	positive regulation of neurological system process	2.992607e-5
GO:0051444	negative regulation of ubiquitin-protein ligase activity	3.021035e-5
GO:0035264	multicellular organism growth	3.123052e-5
GO:0008344	adult locomotory behavior	3.245083e-5
GO:0015949	nucleobase-containing small molecule interconversion	3.453969e-5
GO:0006952	defense response	3.692436e-5
GO:0045664	regulation of neuron differentiation	3.702568e-5
GO:0050806	positive regulation of synaptic transmission	3.811291e-5
GO:0043254	regulation of protein complex assembly	4.254402e-5
GO:0016032	viral reproduction	4.727404e-5
GO:0051340	regulation of ligase activity	4.730798e-5
GO:0042345	regulation of NF-kappaB import into nucleus	4.913643e-5
GO:0072093	metanephric renal vesicle formation	4.913925e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	4.966314e-5
GO:0060079	regulation of excitatory postsynaptic membrane potential	5.001383e-5
GO:0048169	regulation of long-term neuronal synaptic plasticity	5.895422e-5
GO:0061386	closure of optic fissure	6.101720e-5
GO:0035332	positive regulation of hippo signaling cascade	6.101720e-5
GO:0016137	glycoside metabolic process	6.128397e-5
GO:0021553	olfactory nerve development	6.207802e-5
GO:0035752	lysosomal lumen pH elevation	6.352086e-5
GO:0001575	globoside metabolic process	6.352086e-5
GO:0000046	autophagic vacuole fusion	6.352086e-5
GO:0043039	tRNA aminoacylation	6.562157e-5
GO:0007093	mitotic cell cycle checkpoint	6.588573e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	6.630657e-5
GO:0050902	leukocyte adhesive activation	6.630657e-5
GO:0046823	negative regulation of nucleocytoplasmic transport	7.006261e-5
GO:0002765	immune response-inhibiting signal transduction	7.065355e-5
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	7.102966e-5
GO:0060479	lung cell differentiation	7.200432e-5
GO:0051170	nuclear import	7.646054e-5
GO:0006434	seryl-tRNA aminoacylation	8.066217e-5
GO:0051262	protein tetramerization	8.482311e-5
GO:0006606	protein import into nucleus	8.985936e-5
GO:0035235	ionotropic glutamate receptor signaling pathway	9.982774e-5
GO:0006959	humoral immune response	1.049313e-4
GO:0032929	negative regulation of superoxide anion generation	1.063805e-4
GO:0042391	regulation of membrane potential	1.075938e-4
GO:0051320	S phase	1.110104e-4
GO:0051453	regulation of intracellular pH	1.142175e-4
GO:0090317	negative regulation of intracellular protein transport	1.147743e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	1.190042e-4
GO:0000084	S phase of mitotic cell cycle	1.247869e-4
GO:0032271	regulation of protein polymerization	1.249810e-4
GO:0030832	regulation of actin filament length	1.290170e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.295508e-4
GO:0034660	ncRNA metabolic process	1.382351e-4
GO:0016071	mRNA metabolic process	1.435909e-4
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	1.446594e-4
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	1.446594e-4
GO:0006148	inosine catabolic process	1.446594e-4
GO:0006738	nicotinamide riboside catabolic process	1.446594e-4
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	1.446594e-4
GO:0050767	regulation of neurogenesis	1.469436e-4
GO:0051452	intracellular pH reduction	1.472388e-4
GO:0003382	epithelial cell morphogenesis	1.494654e-4
GO:0016139	glycoside catabolic process	1.535456e-4
GO:0048246	macrophage chemotaxis	1.585904e-4
GO:0002339	B cell selection	1.621699e-4
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.625565e-4
GO:0015991	ATP hydrolysis coupled proton transport	1.667453e-4
GO:0007417	central nervous system development	1.690473e-4
GO:0060677	ureteric bud elongation	1.701143e-4
GO:0006563	L-serine metabolic process	1.814156e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.822301e-4
GO:0016242	negative regulation of macroautophagy	1.832972e-4
GO:0051899	membrane depolarization	1.839151e-4
GO:0006565	L-serine catabolic process	1.857831e-4
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	1.860093e-4
GO:0006414	translational elongation	1.939820e-4
GO:0015780	nucleotide-sugar transport	1.945449e-4
GO:0002149	hypochlorous acid biosynthetic process	1.946776e-4
GO:0000075	cell cycle checkpoint	1.965343e-4
GO:0043587	tongue morphogenesis	2.103756e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.119430e-4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	2.134110e-4
GO:0042559	pteridine-containing compound biosynthetic process	2.141269e-4
GO:0007270	neuron-neuron synaptic transmission	2.220088e-4
GO:0030641	regulation of cellular pH	2.258208e-4
GO:0045087	innate immune response	2.478610e-4
GO:0043243	positive regulation of protein complex disassembly	2.566744e-4
GO:0016241	regulation of macroautophagy	2.651059e-4
GO:0009313	oligosaccharide catabolic process	2.794378e-4
GO:0006258	UDP-glucose catabolic process	2.860430e-4
GO:0002344	B cell affinity maturation	2.878977e-4
GO:0042942	D-serine transport	2.878977e-4
GO:0035802	adrenal cortex formation	3.103720e-4
GO:0034509	centromeric core chromatin assembly	3.138083e-4
GO:0009151	purine deoxyribonucleotide metabolic process	3.140201e-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.172575e-4
GO:0030833	regulation of actin filament polymerization	3.242774e-4
GO:0042990	regulation of transcription factor import into nucleus	3.252898e-4
GO:0051648	vesicle localization	3.255903e-4
GO:0060022	hard palate development	3.348278e-4
GO:0008064	regulation of actin polymerization or depolymerization	3.462823e-4
GO:0048713	regulation of oligodendrocyte differentiation	3.499709e-4
GO:0042940	D-amino acid transport	3.551168e-4
GO:0006364	rRNA processing	3.579195e-4
GO:0042339	keratan sulfate metabolic process	3.691414e-4
GO:0051289	protein homotetramerization	3.702227e-4
GO:0042891	antibiotic transport	3.984840e-4
GO:0006448	regulation of translational elongation	4.018668e-4
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	4.104250e-4
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	4.104250e-4
GO:0006518	peptide metabolic process	4.202741e-4
GO:0045851	pH reduction	4.207385e-4
GO:0015810	aspartate transport	4.304665e-4
GO:0051454	intracellular pH elevation	4.341397e-4
GO:0031016	pancreas development	4.387142e-4
GO:0042493	response to drug	4.515704e-4
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	4.523801e-4
GO:0006605	protein targeting	4.560200e-4
GO:0032535	regulation of cellular component size	4.560465e-4
GO:0017148	negative regulation of translation	4.676060e-4
GO:0072384	organelle transport along microtubule	4.847735e-4
GO:0042308	negative regulation of protein import into nucleus	4.973640e-4
GO:0002200	somatic diversification of immune receptors	5.034018e-4
GO:0032764	negative regulation of mast cell cytokine production	5.095040e-4
GO:0009069	serine family amino acid metabolic process	5.108657e-4
GO:0048538	thymus development	5.265290e-4
GO:0047496	vesicle transport along microtubule	5.270177e-4
GO:0071918	urea transmembrane transport	5.374966e-4
GO:0033157	regulation of intracellular protein transport	5.535990e-4
GO:0007035	vacuolar acidification	5.733949e-4
GO:0032269	negative regulation of cellular protein metabolic process	5.743031e-4
GO:0032387	negative regulation of intracellular transport	6.013608e-4
GO:0071779	G1/S transition checkpoint	6.068895e-4
GO:0060923	cardiac muscle cell fate commitment	6.087522e-4
GO:0006418	tRNA aminoacylation for protein translation	6.104003e-4
GO:0019438	aromatic compound biosynthetic process	6.118510e-4
GO:0014823	response to activity	6.213028e-4
GO:0070926	regulation of ATP:ADP antiporter activity	6.324049e-4
GO:0050710	negative regulation of cytokine secretion	6.378628e-4
GO:0000086	G2/M transition of mitotic cell cycle	6.388449e-4
GO:0009062	fatty acid catabolic process	6.519946e-4
GO:0016072	rRNA metabolic process	6.816510e-4
GO:0060555	induction of necroptosis by extracellular signals	6.885937e-4
GO:0042306	regulation of protein import into nucleus	7.087950e-4
GO:0006412	translation	7.102061e-4
GO:0043101	purine-containing compound salvage	7.435160e-4
GO:0021509	roof plate formation	7.526972e-4
GO:0042742	defense response to bacterium	7.760610e-4
GO:0060487	lung epithelial cell differentiation	7.870756e-4
GO:0030521	androgen receptor signaling pathway	7.959510e-4
GO:0007597	blood coagulation, intrinsic pathway	7.966298e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	8.036253e-4
GO:0014009	glial cell proliferation	8.056621e-4
GO:0015813	L-glutamate transport	8.184757e-4
GO:0070683	mitotic cell cycle G2/M transition decatenation checkpoint	8.238623e-4
GO:0022403	cell cycle phase	8.485974e-4
GO:0009308	amine metabolic process	8.717988e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	8.947408e-4
GO:0048715	negative regulation of oligodendrocyte differentiation	9.078937e-4
GO:0048205	COPI coating of Golgi vesicle	9.208337e-4
GO:0010332	response to gamma radiation	9.644381e-4
GO:0007346	regulation of mitotic cell cycle	9.692317e-4
GO:0022415	viral reproductive process	9.707939e-4
GO:0007268	synaptic transmission	9.984149e-4
GO:0002218	activation of innate immune response	1.015264e-3
GO:2000602	regulation of interphase of mitotic cell cycle	1.016042e-3
GO:0007525	somatic muscle development	1.031808e-3
GO:0009262	deoxyribonucleotide metabolic process	1.057063e-3
GO:0034201	response to oleic acid	1.058487e-3
GO:0035425	autocrine signaling	1.077505e-3
GO:0007420	brain development	1.104605e-3
GO:0033153	T cell receptor V(D)J recombination	1.113544e-3
GO:0045616	regulation of keratinocyte differentiation	1.143651e-3
GO:0051403	stress-activated MAPK cascade	1.151661e-3
GO:0060428	lung epithelium development	1.189837e-3
GO:0046318	negative regulation of glucosylceramide biosynthetic process	1.191268e-3
GO:0045343	regulation of MHC class I biosynthetic process	1.198616e-3
GO:0034097	response to cytokine stimulus	1.204761e-3
GO:0002679	respiratory burst involved in defense response	1.205947e-3
GO:0000060	protein import into nucleus, translocation	1.208786e-3
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	1.208786e-3
GO:0009155	purine deoxyribonucleotide catabolic process	1.215752e-3
GO:0072087	renal vesicle development	1.227912e-3
GO:0003338	metanephros morphogenesis	1.228989e-3
GO:0042992	negative regulation of transcription factor import into nucleus	1.228989e-3
GO:0072526	pyridine-containing compound catabolic process	1.232060e-3
GO:0051650	establishment of vesicle localization	1.232826e-3
GO:0021537	telencephalon development	1.240921e-3
GO:0008063	Toll signaling pathway	1.242510e-3
GO:0002376	immune system process	1.260570e-3
GO:0014048	regulation of glutamate secretion	1.280582e-3
GO:0002384	hepatic immune response	1.285873e-3
GO:0046822	regulation of nucleocytoplasmic transport	1.287246e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.289572e-3
GO:0072283	metanephric renal vesicle morphogenesis	1.313203e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.313292e-3
GO:0015820	leucine transport	1.313292e-3
GO:0005993	trehalose catabolic process	1.351351e-3
GO:0072273	metanephric nephron morphogenesis	1.353148e-3
GO:0000082	G1/S transition of mitotic cell cycle	1.370853e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.388133e-3
GO:0061032	visceral serous pericardium development	1.388574e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.388574e-3
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	1.388574e-3
GO:0035635	entry of bacterium into host cell	1.388574e-3
GO:0030862	positive regulation of polarized epithelial cell differentiation	1.388574e-3
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.409080e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	1.422832e-3
GO:0051248	negative regulation of protein metabolic process	1.423391e-3
GO:0071156	regulation of cell cycle arrest	1.429696e-3
GO:0031397	negative regulation of protein ubiquitination	1.430550e-3
GO:0034374	low-density lipoprotein particle remodeling	1.433312e-3
GO:0034383	low-density lipoprotein particle clearance	1.454859e-3
GO:0048678	response to axon injury	1.492020e-3
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	1.497192e-3
GO:0048513	organ development	1.508397e-3
GO:0043043	peptide biosynthetic process	1.568382e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.576970e-3
GO:0044057	regulation of system process	1.589523e-3
GO:0046326	positive regulation of glucose import	1.620451e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.623346e-3
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.645558e-3
GO:0072077	renal vesicle morphogenesis	1.651262e-3
GO:0060049	regulation of protein glycosylation	1.662876e-3
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.678260e-3
GO:0007568	aging	1.680213e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	1.680811e-3
GO:0017038	protein import	1.692319e-3
GO:0007527	adult somatic muscle development	1.722941e-3
GO:0061303	cornea development in camera-type eye	1.745752e-3
GO:0048194	Golgi vesicle budding	1.820918e-3
GO:0021778	oligodendrocyte cell fate specification	1.820918e-3
GO:0031557	induction of programmed cell death in response to chemical stimulus	1.820918e-3
GO:0072329	monocarboxylic acid catabolic process	1.831817e-3
GO:0003281	ventricular septum development	1.852772e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	1.852973e-3
GO:0007632	visual behavior	1.854386e-3
GO:0006903	vesicle targeting	1.890578e-3
GO:0033211	adiponectin-mediated signaling pathway	1.924990e-3
GO:0006520	cellular amino acid metabolic process	1.938548e-3
GO:0045076	regulation of interleukin-2 biosynthetic process	1.982246e-3
GO:0030316	osteoclast differentiation	1.997958e-3
GO:0007267	cell-cell signaling	2.020206e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	2.029880e-3
GO:0030212	hyaluronan metabolic process	2.029880e-3
GO:0045870	positive regulation of retroviral genome replication	2.034433e-3
GO:0046168	glycerol-3-phosphate catabolic process	2.034433e-3
GO:0051223	regulation of protein transport	2.043919e-3
GO:0015800	acidic amino acid transport	2.079182e-3
GO:0043414	macromolecule methylation	2.088696e-3
GO:0072166	posterior mesonephric tubule development	2.091912e-3
GO:0006749	glutathione metabolic process	2.108205e-3
GO:0014049	positive regulation of glutamate secretion	2.110413e-3
GO:0001956	positive regulation of neurotransmitter secretion	2.151880e-3
GO:0001781	neutrophil apoptosis	2.158536e-3
GO:0071379	cellular response to prostaglandin stimulus	2.166044e-3
GO:0007181	transforming growth factor beta receptor complex assembly	2.178935e-3
GO:0021510	spinal cord development	2.186724e-3
GO:0060409	positive regulation of acetylcholine metabolic process	2.190555e-3
GO:0090174	organelle membrane fusion	2.217181e-3
GO:0055070	copper ion homeostasis	2.229882e-3
GO:0031349	positive regulation of defense response	2.276744e-3
GO:0045901	positive regulation of translational elongation	2.361132e-3
GO:0045905	positive regulation of translational termination	2.361132e-3
GO:0006452	translational frameshifting	2.361132e-3
GO:0006298	mismatch repair	2.398803e-3
GO:0043990	histone H2A-S1 phosphorylation	2.440463e-3
GO:0042938	dipeptide transport	2.440463e-3
GO:0051960	regulation of nervous system development	2.446771e-3
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	2.481804e-3
GO:0010828	positive regulation of glucose transport	2.500607e-3
GO:0050769	positive regulation of neurogenesis	2.503336e-3
GO:0016064	immunoglobulin mediated immune response	2.509130e-3
GO:0045445	myoblast differentiation	2.513635e-3
GO:0018199	peptidyl-glutamine modification	2.566283e-3
GO:0000090	mitotic anaphase	2.566283e-3
GO:0022612	gland morphogenesis	2.596501e-3
GO:0006913	nucleocytoplasmic transport	2.629040e-3
GO:0051591	response to cAMP	2.642801e-3
GO:0032836	glomerular basement membrane development	2.647073e-3
GO:0006886	intracellular protein transport	2.673535e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	2.735557e-3
GO:0032386	regulation of intracellular transport	2.778553e-3
GO:0045004	DNA replication proofreading	2.826949e-3
GO:0070165	positive regulation of adiponectin secretion	2.826949e-3
GO:0033031	positive regulation of neutrophil apoptosis	2.826949e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	2.841798e-3
GO:0060040	retinal bipolar neuron differentiation	2.852594e-3
GO:0060563	neuroepithelial cell differentiation	2.910755e-3
GO:0072028	nephron morphogenesis	2.917202e-3
GO:0044130	negative regulation of growth of symbiont in host	2.953657e-3
GO:0007585	respiratory gaseous exchange	2.992152e-3
GO:0006399	tRNA metabolic process	2.996448e-3
GO:0070544	histone H3-K36 demethylation	3.016368e-3
GO:0048679	regulation of axon regeneration	3.068510e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	3.069695e-3
GO:0034138	toll-like receptor 3 signaling pathway	3.141236e-3
GO:0046395	carboxylic acid catabolic process	3.209302e-3
GO:0044106	cellular amine metabolic process	3.260709e-3
GO:0007215	glutamate signaling pathway	3.326941e-3
GO:0009071	serine family amino acid catabolic process	3.339986e-3
GO:0090066	regulation of anatomical structure size	3.359130e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	3.370624e-3
GO:0042340	keratan sulfate catabolic process	3.382714e-3
GO:0003357	noradrenergic neuron differentiation	3.387921e-3
GO:0051622	negative regulation of norepinephrine uptake	3.400288e-3
GO:0070495	negative regulation of thrombin receptor signaling pathway	3.400288e-3
GO:0051585	negative regulation of dopamine uptake	3.400288e-3
GO:0050812	regulation of acyl-CoA biosynthetic process	3.400288e-3
GO:0042159	lipoprotein catabolic process	3.409214e-3
GO:0006729	tetrahydrobiopterin biosynthetic process	3.412631e-3
GO:0006807	nitrogen compound metabolic process	3.416903e-3
GO:0001832	blastocyst growth	3.425729e-3
GO:0050709	negative regulation of protein secretion	3.431394e-3
GO:0002328	pro-B cell differentiation	3.479733e-3
GO:0002034	regulation of blood vessel size by renin-angiotensin	3.514066e-3
GO:0030317	sperm motility	3.541628e-3
GO:0019226	transmission of nerve impulse	3.589125e-3
GO:0006013	mannose metabolic process	3.605218e-3
GO:0002091	negative regulation of receptor internalization	3.626120e-3
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	3.626369e-3
GO:0050877	neurological system process	3.635011e-3
GO:0045540	regulation of cholesterol biosynthetic process	3.661259e-3
GO:0045089	positive regulation of innate immune response	3.666143e-3
GO:0043086	negative regulation of catalytic activity	3.714477e-3
GO:0030855	epithelial cell differentiation	3.777583e-3
GO:0045605	negative regulation of epidermal cell differentiation	3.783847e-3
GO:0006805	xenobiotic metabolic process	3.821212e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.858336e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	3.887901e-3
GO:0048661	positive regulation of smooth muscle cell proliferation	3.911066e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	3.959914e-3
GO:0045019	negative regulation of nitric oxide biosynthetic process	4.017028e-3
GO:0006873	cellular ion homeostasis	4.018058e-3
GO:0072376	protein activation cascade	4.023216e-3
GO:0010507	negative regulation of autophagy	4.046275e-3
GO:0051983	regulation of chromosome segregation	4.051791e-3
GO:0003056	regulation of vascular smooth muscle contraction	4.150114e-3
GO:0051169	nuclear transport	4.166059e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	4.167520e-3
GO:0060674	placenta blood vessel development	4.408838e-3
GO:0032663	regulation of interleukin-2 production	4.476018e-3
GO:0071786	endoplasmic reticulum tubular network organization	4.546171e-3
GO:0032329	serine transport	4.546171e-3
GO:0015986	ATP synthesis coupled proton transport	4.559147e-3
GO:0060087	relaxation of vascular smooth muscle	4.580202e-3
GO:0007275	multicellular organismal development	4.580547e-3
GO:0033555	multicellular organismal response to stress	4.616275e-3
GO:0070201	regulation of establishment of protein localization	4.642827e-3
GO:0031575	mitotic cell cycle G1/S transition checkpoint	4.646616e-3
GO:0034142	toll-like receptor 4 signaling pathway	4.655669e-3
GO:0006635	fatty acid beta-oxidation	4.678603e-3
GO:0043490	malate-aspartate shuttle	4.699591e-3
GO:0006436	tryptophanyl-tRNA aminoacylation	4.699591e-3
GO:0042254	ribosome biogenesis	4.715715e-3
GO:0080134	regulation of response to stress	4.732682e-3
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	4.772217e-3
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	4.786320e-3
GO:0044245	polysaccharide digestion	4.786320e-3
GO:0048285	organelle fission	4.841439e-3
GO:0000305	response to oxygen radical	4.881154e-3
GO:0071569	protein ufmylation	4.896872e-3
GO:0009791	post-embryonic development	4.906643e-3
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	4.910396e-3
GO:0001508	regulation of action potential	4.939483e-3
GO:0051176	positive regulation of sulfur metabolic process	4.950973e-3
GO:0043988	histone H3-S28 phosphorylation	4.964318e-3
GO:0043987	histone H3-S10 phosphorylation	4.964318e-3
GO:0002064	epithelial cell development	4.971685e-3
GO:0055082	cellular chemical homeostasis	5.020463e-3
GO:0044092	negative regulation of molecular function	5.043622e-3
GO:0001824	blastocyst development	5.083210e-3
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	5.089718e-3
GO:0006885	regulation of pH	5.144433e-3
GO:0051322	anaphase	5.170779e-3
GO:0051640	organelle localization	5.197318e-3
GO:0034504	protein localization to nucleus	5.252149e-3
GO:0090181	regulation of cholesterol metabolic process	5.290325e-3
GO:0042129	regulation of T cell proliferation	5.347828e-3
GO:0022414	reproductive process	5.393915e-3
GO:0043149	stress fiber assembly	5.473114e-3
GO:0001963	synaptic transmission, dopaminergic	5.473114e-3
GO:0072298	regulation of metanephric glomerulus development	5.495468e-3
GO:0030595	leukocyte chemotaxis	5.498290e-3
GO:0051656	establishment of organelle localization	5.532068e-3
GO:0051235	maintenance of location	5.599303e-3
GO:0009887	organ morphogenesis	5.615839e-3
GO:0034134	toll-like receptor 2 signaling pathway	5.754207e-3
GO:0034130	toll-like receptor 1 signaling pathway	5.754207e-3
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	5.762462e-3
GO:0061046	regulation of branching involved in lung morphogenesis	5.818853e-3
GO:0045086	positive regulation of interleukin-2 biosynthetic process	5.820170e-3
GO:0043244	regulation of protein complex disassembly	5.835322e-3
GO:0034720	histone H3-K4 demethylation	5.845981e-3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	5.924446e-3
GO:0045629	negative regulation of T-helper 2 cell differentiation	5.927240e-3
GO:0019858	cytosine metabolic process	5.937039e-3
GO:0000003	reproduction	5.967283e-3
GO:0007067	mitosis	6.008293e-3
GO:0030325	adrenal gland development	6.028075e-3
GO:0035112	genitalia morphogenesis	6.028148e-3
GO:0006516	glycoprotein catabolic process	6.086641e-3
GO:0021773	striatal medium spiny neuron differentiation	6.086742e-3
GO:0046591	embryonic leg joint morphogenesis	6.086742e-3
GO:0071956	cellular component maintenance at cellular level	6.113947e-3
GO:0071466	cellular response to xenobiotic stimulus	6.132487e-3
GO:0048537	mucosal-associated lymphoid tissue development	6.212754e-3
GO:0031644	regulation of neurological system process	6.265178e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	6.265751e-3
GO:0014070	response to organic cyclic compound	6.393305e-3
GO:0042762	regulation of sulfur metabolic process	6.439223e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	6.532915e-3
GO:0071158	positive regulation of cell cycle arrest	6.557639e-3
GO:0034763	negative regulation of transmembrane transport	6.557639e-3
GO:0090192	regulation of glomerulus development	6.573185e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	6.624222e-3
GO:0045986	negative regulation of smooth muscle contraction	6.624222e-3
GO:0035021	negative regulation of Rac protein signal transduction	6.661577e-3
GO:0045604	regulation of epidermal cell differentiation	6.726473e-3
GO:0006998	nuclear envelope organization	6.729812e-3
GO:0051384	response to glucocorticoid stimulus	6.733220e-3
GO:0010616	negative regulation of cardiac muscle adaptation	6.776006e-3
GO:0006878	cellular copper ion homeostasis	6.828496e-3
GO:0050808	synapse organization	6.845420e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	6.868303e-3
GO:0009410	response to xenobiotic stimulus	6.879344e-3
GO:0010886	positive regulation of cholesterol storage	6.887232e-3
GO:0033566	gamma-tubulin complex localization	6.936624e-3
GO:0072334	UDP-galactose transmembrane transport	6.936624e-3
GO:0046146	tetrahydrobiopterin metabolic process	7.008265e-3
GO:0002829	negative regulation of type 2 immune response	7.008265e-3
GO:0006422	aspartyl-tRNA aminoacylation	7.045156e-3
GO:0002446	neutrophil mediated immunity	7.082933e-3
GO:0034641	cellular nitrogen compound metabolic process	7.164568e-3
GO:0072210	metanephric nephron development	7.259408e-3
GO:0031347	regulation of defense response	7.262091e-3
GO:0048771	tissue remodeling	7.332795e-3
GO:0043524	negative regulation of neuron apoptosis	7.349602e-3
GO:0050830	defense response to Gram-positive bacterium	7.355837e-3
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.391802e-3
GO:0042398	cellular modified amino acid biosynthetic process	7.482510e-3
GO:0043129	surfactant homeostasis	7.548914e-3
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	7.691456e-3
GO:0001818	negative regulation of cytokine production	7.696902e-3
GO:0009083	branched chain family amino acid catabolic process	7.705425e-3
GO:0034219	carbohydrate transmembrane transport	7.706071e-3
GO:0030010	establishment of cell polarity	7.708262e-3
GO:0050707	regulation of cytokine secretion	7.730101e-3
GO:0001302	replicative cell aging	7.747107e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	7.777362e-3
GO:0048294	negative regulation of isotype switching to IgE isotypes	7.777362e-3
GO:0006954	inflammatory response	7.872544e-3
GO:0044273	sulfur compound catabolic process	7.873022e-3
GO:0071173	spindle assembly checkpoint	7.884068e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.614908e-11
GO:0045796	negative regulation of intestinal cholesterol absorption	1.637677e-11
GO:0010949	negative regulation of intestinal phytosterol absorption	1.637677e-11
GO:0009181	purine ribonucleoside diphosphate catabolic process	1.825709e-10
GO:0046031	ADP metabolic process	2.356413e-10
GO:0046709	IDP catabolic process	5.606765e-10
GO:0046032	ADP catabolic process	5.606765e-10
GO:0060457	negative regulation of digestive system process	1.350375e-9
GO:2000249	regulation of actin cytoskeleton reorganization	1.066350e-8
GO:0009185	ribonucleoside diphosphate metabolic process	1.485487e-8
GO:0051272	positive regulation of cellular component movement	1.888711e-8
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	2.449041e-8
GO:2000147	positive regulation of cell motility	5.617837e-8
GO:0040017	positive regulation of locomotion	7.956836e-8
GO:0051591	response to cAMP	1.152410e-7
GO:0030335	positive regulation of cell migration	1.592843e-7
GO:0051084	'de novo' posttranslational protein folding	1.817037e-7
GO:0009191	ribonucleoside diphosphate catabolic process	6.186279e-7
GO:0032057	negative regulation of translational initiation in response to stress	1.142505e-6
GO:0009134	nucleoside diphosphate catabolic process	1.457604e-6
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.988398e-6
GO:0051085	chaperone mediated protein folding requiring cofactor	2.202866e-6
GO:0051182	coenzyme transport	2.329942e-6
GO:0046452	dihydrofolate metabolic process	2.749801e-6
GO:0060048	cardiac muscle contraction	4.819899e-6
GO:0001579	medium-chain fatty acid transport	5.185084e-6
GO:0051270	regulation of cellular component movement	7.981528e-6
GO:0032055	negative regulation of translation in response to stress	1.145430e-5
GO:0008033	tRNA processing	1.261668e-5
GO:0030240	skeletal muscle thin filament assembly	1.702697e-5
GO:0070869	heterochromatin formation involved in chromatin silencing	1.914825e-5
GO:0032606	type I interferon production	2.143649e-5
GO:0045329	carnitine biosynthetic process	2.729210e-5
GO:2000145	regulation of cell motility	2.829197e-5
GO:0046700	heterocycle catabolic process	3.404544e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	3.544287e-5
GO:0051932	synaptic transmission, GABAergic	3.560659e-5
GO:0042345	regulation of NF-kappaB import into nucleus	4.316239e-5
GO:0071671	regulation of smooth muscle cell chemotaxis	4.365274e-5
GO:0051567	histone H3-K9 methylation	4.794164e-5
GO:0006666	3-keto-sphinganine metabolic process	5.055991e-5
GO:0030334	regulation of cell migration	5.640297e-5
GO:0034470	ncRNA processing	5.855585e-5
GO:0014866	skeletal myofibril assembly	6.120025e-5
GO:0043154	negative regulation of caspase activity	6.151778e-5
GO:0002016	regulation of blood volume by renin-angiotensin	6.445943e-5
GO:0050435	beta-amyloid metabolic process	6.977519e-5
GO:0006644	phospholipid metabolic process	7.558638e-5
GO:0019319	hexose biosynthetic process	7.903413e-5
GO:0060047	heart contraction	7.943164e-5
GO:0030299	intestinal cholesterol absorption	7.946839e-5
GO:0045292	nuclear mRNA cis splicing, via spliceosome	8.035358e-5
GO:0007217	tachykinin receptor signaling pathway	8.580197e-5
GO:0045471	response to ethanol	9.162180e-5
GO:0010665	regulation of cardiac muscle cell apoptosis	9.513123e-5
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	1.002499e-4
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	1.002499e-4
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	1.002499e-4
GO:0016074	snoRNA metabolic process	1.016908e-4
GO:0071260	cellular response to mechanical stimulus	1.054024e-4
GO:0045351	type I interferon biosynthetic process	1.150711e-4
GO:0048935	peripheral nervous system neuron development	1.242747e-4
GO:0019637	organophosphate metabolic process	1.243255e-4
GO:0003015	heart process	1.314343e-4
GO:0006548	histidine catabolic process	1.538220e-4
GO:0035562	negative regulation of chromatin binding	1.590365e-4
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	1.590365e-4
GO:0070535	histone H2A K63-linked ubiquitination	1.670337e-4
GO:0044205	'de novo' UMP biosynthetic process	1.735875e-4
GO:0040012	regulation of locomotion	1.789742e-4
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.854933e-4
GO:0000045	autophagic vacuole assembly	1.902616e-4
GO:0035176	social behavior	1.991906e-4
GO:0090184	positive regulation of kidney development	2.340696e-4
GO:0006206	pyrimidine base metabolic process	2.364158e-4
GO:0009132	nucleoside diphosphate metabolic process	2.371178e-4
GO:0045875	negative regulation of sister chromatid cohesion	2.428738e-4
GO:0044255	cellular lipid metabolic process	2.614551e-4
GO:0071922	regulation of cohesin localization to chromatin	2.616013e-4
GO:0015876	acetyl-CoA transport	2.657544e-4
GO:0006547	histidine metabolic process	2.661761e-4
GO:0032507	maintenance of protein location in cell	2.826378e-4
GO:0009056	catabolic process	3.490946e-4
GO:0016180	snRNA processing	3.625218e-4
GO:0071673	positive regulation of smooth muscle cell chemotaxis	3.698135e-4
GO:0042938	dipeptide transport	3.698135e-4
GO:0045824	negative regulation of innate immune response	3.718470e-4
GO:0007608	sensory perception of smell	3.847616e-4
GO:0050795	regulation of behavior	3.873540e-4
GO:0070208	protein heterotrimerization	3.943903e-4
GO:0043555	regulation of translation in response to stress	4.059292e-4
GO:0034504	protein localization to nucleus	4.160207e-4
GO:0043410	positive regulation of MAPKKK cascade	4.221652e-4
GO:0014910	regulation of smooth muscle cell migration	4.241296e-4
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	4.434232e-4
GO:0048665	neuron fate specification	4.574158e-4
GO:0042335	cuticle development	4.610148e-4
GO:0018960	4-nitrophenol metabolic process	4.610148e-4
GO:0032077	positive regulation of deoxyribonuclease activity	4.610148e-4
GO:0046330	positive regulation of JNK cascade	4.679512e-4
GO:0031293	membrane protein intracellular domain proteolysis	4.702270e-4
GO:0034205	beta-amyloid formation	4.702270e-4
GO:0035814	negative regulation of renal sodium excretion	4.973809e-4
GO:0042414	epinephrine metabolic process	4.975798e-4
GO:0046364	monosaccharide biosynthetic process	5.019700e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	5.019934e-4
GO:0044281	small molecule metabolic process	5.122105e-4
GO:0009231	riboflavin biosynthetic process	5.154306e-4
GO:0045343	regulation of MHC class I biosynthetic process	5.561144e-4
GO:0043558	regulation of translational initiation in response to stress	5.561144e-4
GO:0006972	hyperosmotic response	6.179158e-4
GO:0010459	negative regulation of heart rate	6.179158e-4
GO:0048520	positive regulation of behavior	6.536069e-4
GO:0002376	immune system process	6.539141e-4
GO:0044270	cellular nitrogen compound catabolic process	6.723529e-4
GO:0051917	regulation of fibrinolysis	7.017428e-4
GO:0042727	flavin-containing compound biosynthetic process	7.217535e-4
GO:0003329	pancreatic PP cell fate commitment	7.217535e-4
GO:0001869	negative regulation of complement activation, lectin pathway	7.217535e-4
GO:0003326	pancreatic A cell fate commitment	7.217535e-4
GO:0050921	positive regulation of chemotaxis	7.296400e-4
GO:0042760	very long-chain fatty acid catabolic process	7.433261e-4
GO:0045884	regulation of survival gene product expression	7.496873e-4
GO:0034660	ncRNA metabolic process	7.670466e-4
GO:0001937	negative regulation of endothelial cell proliferation	7.767633e-4
GO:0007182	common-partner SMAD protein phosphorylation	7.854618e-4
GO:0009083	branched chain family amino acid catabolic process	7.875162e-4
GO:0046488	phosphatidylinositol metabolic process	8.028537e-4
GO:0006952	defense response	8.115079e-4
GO:0051918	negative regulation of fibrinolysis	8.210796e-4
GO:0006006	glucose metabolic process	8.220887e-4
GO:0071364	cellular response to epidermal growth factor stimulus	8.361565e-4
GO:0042987	amyloid precursor protein catabolic process	8.405003e-4
GO:0021515	cell differentiation in spinal cord	8.462556e-4
GO:0061302	smooth muscle cell-matrix adhesion	8.541185e-4
GO:0048844	artery morphogenesis	8.591596e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	8.672191e-4
GO:0042089	cytokine biosynthetic process	8.815213e-4
GO:0006094	gluconeogenesis	9.057846e-4
GO:0000183	chromatin silencing at rDNA	9.245508e-4
GO:0042158	lipoprotein biosynthetic process	9.677004e-4
GO:0010812	negative regulation of cell-substrate adhesion	9.813992e-4
GO:0051383	kinetochore organization	9.883026e-4
GO:0007509	mesoderm migration involved in gastrulation	1.008391e-3
GO:0009620	response to fungus	1.013818e-3
GO:0015887	pantothenate transmembrane transport	1.029783e-3
GO:0015878	biotin transport	1.029783e-3
GO:0009612	response to mechanical stimulus	1.050514e-3
GO:0034655	nucleobase-containing compound catabolic process	1.069071e-3
GO:0014888	striated muscle adaptation	1.069362e-3
GO:0008078	mesodermal cell migration	1.077528e-3
GO:0016073	snRNA metabolic process	1.081305e-3
GO:0090303	positive regulation of wound healing	1.082440e-3
GO:0021759	globus pallidus development	1.082440e-3
GO:0071345	cellular response to cytokine stimulus	1.089819e-3
GO:0007016	cytoskeletal anchoring at plasma membrane	1.103201e-3
GO:0042990	regulation of transcription factor import into nucleus	1.142857e-3
GO:0032386	regulation of intracellular transport	1.159209e-3
GO:0032879	regulation of localization	1.177262e-3
GO:0043589	skin morphogenesis	1.202611e-3
GO:0010033	response to organic substance	1.215191e-3
GO:0015893	drug transport	1.240176e-3
GO:0021522	spinal cord motor neuron differentiation	1.310091e-3
GO:0006518	peptide metabolic process	1.316477e-3
GO:0034505	tooth mineralization	1.320070e-3
GO:0070986	left/right axis specification	1.326508e-3
GO:0046341	CDP-diacylglycerol metabolic process	1.326508e-3
GO:0021629	olfactory nerve structural organization	1.326508e-3
GO:0043084	penile erection	1.345237e-3
GO:0071670	smooth muscle cell chemotaxis	1.371127e-3
GO:0060981	cell migration involved in coronary angiogenesis	1.371127e-3
GO:0016339	calcium-dependent cell-cell adhesion	1.374093e-3
GO:0016578	histone deubiquitination	1.431852e-3
GO:0007033	vacuole organization	1.461954e-3
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	1.536878e-3
GO:0016236	macroautophagy	1.564183e-3
GO:0060221	retinal rod cell differentiation	1.577013e-3
GO:0071548	response to dexamethasone stimulus	1.629732e-3
GO:0001936	regulation of endothelial cell proliferation	1.650395e-3
GO:0021517	ventral spinal cord development	1.654526e-3
GO:0070164	negative regulation of adiponectin secretion	1.737239e-3
GO:0071217	cellular response to external biotic stimulus	1.737239e-3
GO:0034474	U2 snRNA 3'-end processing	1.737239e-3
GO:0035505	positive regulation of myosin light chain kinase activity	1.737239e-3
GO:0051382	kinetochore assembly	1.745687e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	1.745687e-3
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	1.748750e-3
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	1.748750e-3
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	1.748750e-3
GO:0035622	intrahepatic bile duct development	1.748750e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	1.774137e-3
GO:0019538	protein metabolic process	1.813867e-3
GO:0006586	indolalkylamine metabolic process	1.859658e-3
GO:0031960	response to corticosteroid stimulus	1.864572e-3
GO:0006207	'de novo' pyrimidine base biosynthetic process	1.895236e-3
GO:0006568	tryptophan metabolic process	1.897379e-3
GO:0048635	negative regulation of muscle organ development	1.900799e-3
GO:0045885	positive regulation of survival gene product expression	1.926224e-3
GO:0051542	elastin biosynthetic process	1.933382e-3
GO:0048553	negative regulation of metalloenzyme activity	1.933382e-3
GO:0009082	branched chain family amino acid biosynthetic process	1.946190e-3
GO:0032103	positive regulation of response to external stimulus	1.952691e-3
GO:0006399	tRNA metabolic process	1.971116e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	2.024126e-3
GO:0010466	negative regulation of peptidase activity	2.038269e-3
GO:0071214	cellular response to abiotic stimulus	2.040605e-3
GO:0009081	branched chain family amino acid metabolic process	2.048944e-3
GO:0042375	quinone cofactor metabolic process	2.075863e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	2.086752e-3
GO:0009589	detection of UV	2.086752e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	2.086752e-3
GO:0043043	peptide biosynthetic process	2.155787e-3
GO:0060973	cell migration involved in heart development	2.156707e-3
GO:0006970	response to osmotic stress	2.158447e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2.165036e-3
GO:0009112	nucleobase metabolic process	2.181797e-3
GO:0034284	response to monosaccharide stimulus	2.186103e-3
GO:0015816	glycine transport	2.195913e-3
GO:0044282	small molecule catabolic process	2.204378e-3
GO:0034502	protein localization to chromosome	2.222962e-3
GO:0042982	amyloid precursor protein metabolic process	2.357689e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	2.385733e-3
GO:0043950	positive regulation of cAMP-mediated signaling	2.385733e-3
GO:0031529	ruffle organization	2.385971e-3
GO:0006213	pyrimidine nucleoside metabolic process	2.390360e-3
GO:0070613	regulation of protein processing	2.394402e-3
GO:0006955	immune response	2.415201e-3
GO:0042493	response to drug	2.431541e-3
GO:0006002	fructose 6-phosphate metabolic process	2.453212e-3
GO:0060137	maternal process involved in parturition	2.466936e-3
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	2.525808e-3
GO:0046483	heterocycle metabolic process	2.575919e-3
GO:0055086	nucleobase-containing small molecule metabolic process	2.597315e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	2.608895e-3
GO:0035601	protein deacylation	2.614846e-3
GO:0006497	protein lipidation	2.666387e-3
GO:0071320	cellular response to cAMP	2.717976e-3
GO:0045087	innate immune response	2.740794e-3
GO:0042487	regulation of odontogenesis of dentine-containing tooth	2.742174e-3
GO:0042107	cytokine metabolic process	2.821097e-3
GO:0002573	myeloid leukocyte differentiation	2.850632e-3
GO:0007620	copulation	2.874683e-3
GO:0044057	regulation of system process	2.904432e-3
GO:0072034	renal vesicle induction	2.951352e-3
GO:0051179	localization	2.992635e-3
GO:0042696	menarche	3.038532e-3
GO:0070534	protein K63-linked ubiquitination	3.042957e-3
GO:0002286	T cell activation involved in immune response	3.085605e-3
GO:0006476	protein deacetylation	3.103661e-3
GO:0051531	NFAT protein import into nucleus	3.227576e-3
GO:0045426	quinone cofactor biosynthetic process	3.254068e-3
GO:0061103	carotid body glomus cell differentiation	3.267483e-3
GO:0061104	adrenal chromaffin cell differentiation	3.267483e-3
GO:0003359	noradrenergic neuron fate commitment	3.267483e-3
GO:0061102	stomach neuroendocrine cell differentiation	3.267483e-3
GO:0071259	cellular response to magnetism	3.267483e-3
GO:0061100	lung neuroendocrine cell differentiation	3.267483e-3
GO:0007400	neuroblast fate determination	3.267483e-3
GO:0060165	regulation of timing of subpallium neuron differentiation	3.267483e-3
GO:0051668	localization within membrane	3.293285e-3
GO:0030307	positive regulation of cell growth	3.296155e-3
GO:0009746	response to hexose stimulus	3.300239e-3
GO:0051705	behavioral interaction between organisms	3.384505e-3
GO:0032863	activation of Rac GTPase activity	3.503687e-3
GO:0051651	maintenance of location in cell	3.515074e-3
GO:0043628	ncRNA 3'-end processing	3.525952e-3
GO:0042628	mating plug formation	3.525952e-3
GO:0010656	negative regulation of muscle cell apoptosis	3.534369e-3
GO:0048514	blood vessel morphogenesis	3.614547e-3
GO:0044111	development involved in symbiotic interaction	3.655773e-3
GO:0035021	negative regulation of Rac protein signal transduction	3.655773e-3
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	3.655773e-3
GO:0006172	ADP biosynthetic process	3.655773e-3
GO:0019089	transmission of virus	3.655773e-3
GO:0001959	regulation of cytokine-mediated signaling pathway	3.681366e-3
GO:0033365	protein localization to organelle	3.693913e-3
GO:0032101	regulation of response to external stimulus	3.762009e-3
GO:0060840	artery development	3.770903e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	3.824377e-3
GO:0006195	purine nucleotide catabolic process	4.011550e-3
GO:0006629	lipid metabolic process	4.017710e-3
GO:0045185	maintenance of protein location	4.058071e-3
GO:0071474	cellular hyperosmotic response	4.173506e-3
GO:0071394	cellular response to testosterone stimulus	4.173506e-3
GO:0051935	glutamate uptake involved in synaptic transmission	4.184729e-3
GO:0006506	GPI anchor biosynthetic process	4.192792e-3
GO:0006457	protein folding	4.228437e-3
GO:0009743	response to carbohydrate stimulus	4.270297e-3
GO:0097107	postsynaptic density assembly	4.272877e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	4.272877e-3
GO:0060409	positive regulation of acetylcholine metabolic process	4.272877e-3
GO:0008063	Toll signaling pathway	4.272877e-3
GO:0010273	detoxification of copper ion	4.272877e-3
GO:0019442	tryptophan catabolic process to acetyl-CoA	4.272877e-3
GO:0048193	Golgi vesicle transport	4.314285e-3
GO:0050920	regulation of chemotaxis	4.317935e-3
GO:0007162	negative regulation of cell adhesion	4.401961e-3
GO:0006578	betaine biosynthetic process	4.402067e-3
GO:0072523	purine-containing compound catabolic process	4.404312e-3
GO:0002070	epithelial cell maturation	4.411867e-3
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	4.485949e-3
GO:0035691	macrophage migration inhibitory factor signaling pathway	4.485949e-3
GO:0044241	lipid digestion	4.540129e-3
GO:0071168	protein localization to chromatin	4.553562e-3
GO:0032811	negative regulation of epinephrine secretion	4.553562e-3
GO:0050907	detection of chemical stimulus involved in sensory perception	4.574959e-3
GO:0003008	system process	4.603559e-3
GO:0030449	regulation of complement activation	4.628954e-3
GO:0032273	positive regulation of protein polymerization	4.646131e-3
GO:0042994	cytoplasmic sequestering of transcription factor	4.682036e-3
GO:0060759	regulation of response to cytokine stimulus	4.710416e-3
GO:0055003	cardiac myofibril assembly	4.720703e-3
GO:0009166	nucleotide catabolic process	4.822363e-3
GO:0001878	response to yeast	4.920921e-3
GO:0009310	amine catabolic process	4.933384e-3
GO:0009628	response to abiotic stimulus	4.952979e-3
GO:0032964	collagen biosynthetic process	4.996250e-3
GO:0007158	neuron cell-cell adhesion	5.025749e-3
GO:0007606	sensory perception of chemical stimulus	5.042670e-3
GO:0060350	endochondral bone morphogenesis	5.056142e-3
GO:0045843	negative regulation of striated muscle tissue development	5.179824e-3
GO:0046822	regulation of nucleocytoplasmic transport	5.211348e-3
GO:2000821	regulation of grooming behavior	5.256648e-3
GO:0006725	cellular aromatic compound metabolic process	5.271509e-3
GO:0016310	phosphorylation	5.316392e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	5.367957e-3
GO:0009992	cellular water homeostasis	5.367957e-3
GO:0006685	sphingomyelin catabolic process	5.367957e-3
GO:0051235	maintenance of location	5.466149e-3
GO:0006855	drug transmembrane transport	5.605603e-3
GO:0060729	intestinal epithelial structure maintenance	5.607972e-3
GO:0045732	positive regulation of protein catabolic process	5.632551e-3
GO:0048102	autophagic cell death	5.787045e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5.787045e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	5.823478e-3
GO:0002082	regulation of oxidative phosphorylation	5.823478e-3
GO:0035883	enteroendocrine cell differentiation	5.823478e-3
GO:0005996	monosaccharide metabolic process	5.851322e-3
GO:0042796	snRNA transcription from RNA polymerase III promoter	5.968354e-3
GO:0051545	negative regulation of elastin biosynthetic process	5.968354e-3
GO:0042795	snRNA transcription from RNA polymerase II promoter	5.968354e-3
GO:0006709	progesterone catabolic process	5.968354e-3
GO:0030316	osteoclast differentiation	5.983388e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	6.060125e-3
GO:0060737	prostate gland morphogenetic growth	6.077489e-3
GO:0043501	skeletal muscle adaptation	6.092871e-3
GO:0021953	central nervous system neuron differentiation	6.150000e-3
GO:0051220	cytoplasmic sequestering of protein	6.161238e-3
GO:0001568	blood vessel development	6.205652e-3
GO:0002035	brain renin-angiotensin system	6.269100e-3
GO:0019221	cytokine-mediated signaling pathway	6.284049e-3
GO:0032331	negative regulation of chondrocyte differentiation	6.316827e-3
GO:0007173	epidermal growth factor receptor signaling pathway	6.433154e-3
GO:0009749	response to glucose stimulus	6.441081e-3
GO:0021553	olfactory nerve development	6.747259e-3
GO:0009072	aromatic amino acid family metabolic process	6.754382e-3
GO:0010810	regulation of cell-substrate adhesion	6.755177e-3
GO:2000741	positive regulation of mesenchymal stem cell differentiation	6.757981e-3
GO:0019100	male germ-line sex determination	6.834785e-3
GO:0019318	hexose metabolic process	6.974331e-3
GO:0006360	transcription from RNA polymerase I promoter	7.045595e-3
GO:0019098	reproductive behavior	7.094593e-3
GO:0050930	induction of positive chemotaxis	7.280677e-3
GO:0048241	epinephrine transport	7.325354e-3
GO:0009154	purine ribonucleotide catabolic process	7.461248e-3
GO:0010226	response to lithium ion	7.547432e-3
GO:0034516	response to vitamin B6	7.548353e-3
GO:0043420	anthranilate metabolic process	7.548353e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	7.548353e-3
GO:0033602	negative regulation of dopamine secretion	7.581125e-3
GO:0035572	N-terminal peptidyl-serine dimethylation	7.714868e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	7.714868e-3
GO:0035573	N-terminal peptidyl-serine trimethylation	7.714868e-3
GO:0018016	N-terminal peptidyl-proline dimethylation	7.714868e-3
GO:0014005	microglia development	7.714868e-3
GO:0018012	N-terminal peptidyl-alanine trimethylation	7.714868e-3
GO:0031116	positive regulation of microtubule polymerization	7.764862e-3
GO:0010040	response to iron(II) ion	7.895735e-3
GO:0072527	pyrimidine-containing compound metabolic process	7.966067e-3
GO:0002521	leukocyte differentiation	8.066504e-3
GO:0010038	response to metal ion	8.104808e-3
GO:0046854	phosphatidylinositol phosphorylation	8.247648e-3
GO:0003415	chondrocyte hypertrophy	8.249886e-3
GO:0033157	regulation of intracellular protein transport	8.273732e-3
GO:0051414	response to cortisol stimulus	8.275394e-3
GO:0033057	multicellular organismal reproductive behavior	8.328968e-3
GO:0042891	antibiotic transport	8.476217e-3
GO:0071872	cellular response to epinephrine stimulus	8.476217e-3
GO:0032534	regulation of microvillus assembly	8.476217e-3
GO:0042534	regulation of tumor necrosis factor biosynthetic process	8.492230e-3
GO:0015758	glucose transport	8.579538e-3
GO:0050804	regulation of synaptic transmission	8.616019e-3
GO:0046165	alcohol biosynthetic process	8.691410e-3
GO:0014911	positive regulation of smooth muscle cell migration	8.754794e-3
GO:0043550	regulation of lipid kinase activity	8.837656e-3
GO:0015870	acetylcholine transport	8.904457e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	8.904457e-3
GO:0042993	positive regulation of transcription factor import into nucleus	8.981198e-3
GO:0045661	regulation of myoblast differentiation	9.035990e-3
GO:0006661	phosphatidylinositol biosynthetic process	9.045052e-3
GO:0071625	vocalization behavior	9.075004e-3
GO:0051969	regulation of transmission of nerve impulse	9.086980e-3
GO:0051051	negative regulation of transport	9.320222e-3
GO:0046164	alcohol catabolic process	9.437908e-3
GO:0009396	folic acid-containing compound biosynthetic process	9.466503e-3
GO:0006744	ubiquinone biosynthetic process	9.466503e-3
GO:0070542	response to fatty acid	9.648051e-3
GO:0016049	cell growth	9.691266e-3
GO:0006622	protein targeting to lysosome	9.835212e-3
GO:0001306	age-dependent response to oxidative stress	9.869112e-3
GO:0070849	response to epidermal growth factor stimulus	9.989347e-3
GO:2000822	regulation of behavioral fear response	9.989556e-3
GO:0035881	amacrine cell differentiation	1.003343e-2
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	1.003343e-2
GO:0002544	chronic inflammatory response	1.007502e-2
GO:0042220	response to cocaine	1.022077e-2
GO:0032891	negative regulation of organic acid transport	1.031110e-2
GO:0060547	negative regulation of necrotic cell death	1.036745e-2
GO:0006007	glucose catabolic process	1.037118e-2
GO:0051956	negative regulation of amino acid transport	1.039273e-2
GO:0060690	epithelial cell differentiation involved in salivary gland development	1.043662e-2
GO:0046654	tetrahydrofolate biosynthetic process	1.043662e-2
GO:0048588	developmental cell growth	1.056570e-2
GO:0051170	nuclear import	1.062706e-2
GO:0050916	sensory perception of sweet taste	1.063697e-2
GO:0060163	subpallium neuron fate commitment	1.063697e-2
GO:0019805	quinolinate biosynthetic process	1.063697e-2
GO:0002071	glandular epithelial cell maturation	1.063697e-2
GO:0048660	regulation of smooth muscle cell proliferation	1.072970e-2
GO:0034097	response to cytokine stimulus	1.081982e-2
GO:0043500	muscle adaptation	1.090155e-2
GO:0060180	female mating behavior	1.093384e-2
GO:0044283	small molecule biosynthetic process	1.110587e-2
GO:0009755	hormone-mediated signaling pathway	1.111428e-2
GO:0009261	ribonucleotide catabolic process	1.118845e-2
GO:0009309	amine biosynthetic process	1.126823e-2
GO:0090068	positive regulation of cell cycle process	1.130202e-2
GO:0055002	striated muscle cell development	1.133026e-2
GO:0008156	negative regulation of DNA replication	1.133558e-2
GO:0018107	peptidyl-threonine phosphorylation	1.149716e-2
GO:0030277	maintenance of gastrointestinal epithelium	1.170811e-2
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	1.170811e-2
GO:0006882	cellular zinc ion homeostasis	1.186709e-2
GO:0031272	regulation of pseudopodium assembly	1.187458e-2
GO:0006950	response to stress	1.196147e-2
GO:0042402	cellular biogenic amine catabolic process	1.199413e-2
GO:0048554	positive regulation of metalloenzyme activity	1.205741e-2
GO:0035722	interleukin-12-mediated signaling pathway	1.205741e-2
GO:0060516	primary prostatic bud elongation	1.205741e-2
GO:0015874	norepinephrine transport	1.205741e-2
GO:0010815	bradykinin catabolic process	1.205741e-2
GO:0031032	actomyosin structure organization	1.206184e-2
GO:0042100	B cell proliferation	1.216415e-2
GO:0045663	positive regulation of myoblast differentiation	1.216937e-2
GO:0055006	cardiac cell development	1.220271e-2
GO:0007184	SMAD protein import into nucleus	1.226104e-2
GO:0008645	hexose transport	1.230029e-2
GO:0043279	response to alkaloid	1.230763e-2
GO:0000038	very long-chain fatty acid metabolic process	1.240809e-2
GO:0002252	immune effector process	1.242409e-2
GO:0009259	ribonucleotide metabolic process	1.243852e-2
GO:0010811	positive regulation of cell-substrate adhesion	1.259155e-2
GO:0051704	multi-organism process	1.262732e-2
GO:0010232	vascular transport	1.269789e-2
GO:0006891	intra-Golgi vesicle-mediated transport	1.271221e-2
GO:0045575	basophil activation	1.272868e-2
GO:0015868	purine ribonucleotide transport	1.275575e-2
GO:0070933	histone H4 deacetylation	1.275575e-2
GO:0007567	parturition	1.275575e-2
GO:0070935	3'-UTR-mediated mRNA stabilization	1.276476e-2
GO:0003094	glomerular filtration	1.276476e-2
GO:0006606	protein import into nucleus	1.287851e-2
GO:0001958	endochondral ossification	1.291576e-2
GO:0042108	positive regulation of cytokine biosynthetic process	1.299062e-2
GO:0030097	hemopoiesis	1.300712e-2
GO:0031113	regulation of microtubule polymerization	1.306241e-2
GO:0045080	positive regulation of chemokine biosynthetic process	1.313001e-2
GO:0042347	negative regulation of NF-kappaB import into nucleus	1.313001e-2
GO:0006570	tyrosine metabolic process	1.313001e-2
GO:0090162	establishment of epithelial cell polarity	1.319960e-2
GO:0035767	endothelial cell chemotaxis	1.324080e-2
GO:0045924	regulation of female receptivity	1.324080e-2
GO:0034770	histone H4-K20 methylation	1.348477e-2
GO:0006954	inflammatory response	1.355533e-2
GO:0050892	intestinal absorption	1.369370e-2
GO:0007618	mating	1.371662e-2
GO:0045088	regulation of innate immune response	1.374701e-2
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.390980e-2
GO:0009116	nucleoside metabolic process	1.414435e-2
GO:0019320	hexose catabolic process	1.429153e-2
GO:0030239	myofibril assembly	1.429447e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.432309e-2
GO:0042780	tRNA 3'-end processing	1.443706e-2
GO:0010041	response to iron(III) ion	1.443706e-2
GO:0045022	early endosome to late endosome transport	1.449984e-2
GO:0014912	negative regulation of smooth muscle cell migration	1.454525e-2
GO:0008015	blood circulation	1.459718e-2
GO:0055013	cardiac muscle cell development	1.460546e-2
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	1.472271e-2
GO:0009395	phospholipid catabolic process	1.477426e-2