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Coexpression cluster:C1773

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Full id: C1773_smooth_heart_sacrococcigeal_aorta_bladder_basal_rectum



Phase1 CAGE Peaks

Hg19::chr17:12569199..12569216,+p1@MYOCD
Hg19::chr17:12569325..12569344,+p2@MYOCD
Hg19::chr17:12569359..12569380,+p3@MYOCD
Hg19::chr17:12569384..12569402,+p4@MYOCD
Hg19::chr17:12569472..12569482,+p5@MYOCD


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism7.75e-25115
multi-tissue structure3.50e-15347
multi-cellular organism9.68e-13659
anatomical cluster4.67e-12286
muscle tissue8.73e-1263
musculature8.73e-1263
musculature of body8.73e-1263
somite2.03e-1183
paraxial mesoderm2.03e-1183
presomitic mesoderm2.03e-1183
presumptive segmental plate2.03e-1183
trunk paraxial mesoderm2.03e-1183
presumptive paraxial mesoderm2.03e-1183
organism subdivision2.12e-11365
skeletal muscle tissue1.09e-1061
striated muscle tissue1.09e-1061
myotome1.09e-1061
anatomical conduit2.12e-10241
splanchnic layer of lateral plate mesoderm4.52e-1084
tube3.68e-09194
dermomyotome1.19e-0870
smooth muscle tissue1.32e-0815
cell layer1.79e-08312
epithelium2.01e-08309
anatomical system2.22e-08625
anatomical group3.00e-08626
artery3.54e-0842
arterial blood vessel3.54e-0842
arterial system3.54e-0842
systemic artery3.79e-0833
systemic arterial system3.79e-0833
embryo8.27e-08612
trunk mesenchyme1.03e-07143
neural tube1.47e-0757
neural rod1.47e-0757
future spinal cord1.47e-0757
neural keel1.47e-0757
blood vessel2.05e-0760
epithelial tube open at both ends2.05e-0760
blood vasculature2.05e-0760
vascular cord2.05e-0760
multilaminar epithelium3.36e-0782
neural plate3.47e-0786
presumptive neural plate3.47e-0786
blood vessel smooth muscle7.04e-0710
arterial system smooth muscle7.04e-0710
artery smooth muscle tissue7.04e-0710
aorta smooth muscle tissue7.04e-0710
neurectoderm7.10e-0790
embryonic structure7.16e-07605
developing anatomical structure7.16e-07605
primary circulatory organ9.08e-0727


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.