MCL coexpression mm9:454

Phase1 CAGE Peaks

	Short description
Mm9::chr10:4922184..4922209,+	p@chr10:4922184..4922209 +
Mm9::chr11:110006928..110006939,+	p@chr11:110006928..110006939 +
Mm9::chr11:75475116..75475125,+	p19@Myo1c
Mm9::chr13:60581723..60581732,-	p@chr13:60581723..60581732 -
Mm9::chr16:33124135..33124150,-	p@chr16:33124135..33124150 -
Mm9::chr2:153426878..153426919,+	p@chr2:153426878..153426919 +
Mm9::chr2:158037521..158037530,-	p@chr2:158037521..158037530 -
Mm9::chr3:107041575..107041625,-	p1@Prok1
Mm9::chr4:11542152..11542159,-	p1@ENSMUST00000148576 p1@uc008rzu.1
Mm9::chr4:138015834..138015847,-	p@chr4:138015834..138015847 -
Mm9::chr4:41577595..41577612,+	p@chr4:41577595..41577612 +
Mm9::chr4:41577627..41577640,+	p@chr4:41577627..41577640 +
Mm9::chr5:22095470..22095488,-	p@chr5:22095470..22095488 -
Mm9::chr7:14840233..14840239,-	p1@Sult2a6
Mm9::chr7:85980668..85980685,-	p@chr7:85980668..85980685 -
Mm9::chrX:136369277..136369283,-	p@chrX:136369277..136369283 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045160	myosin I complex	0.009203966471265
GO:0016461	unconventional myosin complex	0.0138051932993965
GO:0032420	stereocilium	0.0230042431219055
GO:0032421	stereocilium bundle	0.0230042431219055
GO:0008022	protein C-terminus binding	0.0239224461872794
GO:0005902	microvillus	0.0260664748441257
GO:0005903	brush border	0.0275967712637765
GO:0007623	circadian rhythm	0.0306555151069646
GO:0045765	regulation of angiogenesis	0.0306555151069646
GO:0000187	activation of MAPK activity	0.0331025101815151
GO:0043406	positive regulation of MAP kinase activity	0.0342681020504265
GO:0016459	myosin complex	0.0424111867249851
GO:0043405	regulation of MAP kinase activity	0.0424111867249851

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
liver	6.21e-22	22
epithelial sac	6.21e-22	22
digestive gland	6.21e-22	22
epithelium of foregut-midgut junction	6.21e-22	22
anatomical boundary	6.21e-22	22
hepatobiliary system	6.21e-22	22
foregut-midgut junction	6.21e-22	22
hepatic diverticulum	6.21e-22	22
liver primordium	6.21e-22	22
septum transversum	6.21e-22	22
liver bud	6.21e-22	22
digestive tract diverticulum	7.81e-21	23
sac	7.81e-21	23
exocrine gland	6.71e-19	25
exocrine system	6.71e-19	25
trunk mesenchyme	4.76e-09	45
epithelial tube	1.57e-08	47
abdomen element	4.71e-08	49
abdominal segment element	4.71e-08	49
abdominal segment of trunk	4.71e-08	49
abdomen	4.71e-08	49
gut epithelium	7.74e-07	55

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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