UBERON:0002106
From FANTOM5_SSTAR
Name: | spleen | ||
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Definition: | "Organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system.[1] In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron.[2] It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells." [Wikipedia:Spleen] | ||
Xrefs: |
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Synonyms: | "splen, lien" RELATED LATIN [Wikipedia:Spleen] | ||
Comments: | Taxon notes: Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) [PMID:20959416] | ||
Alt_id: | UBERON:FMA_7196-MA_0000141-MIAA_0000085-XAO_0000328-ZFA_0000436 | ||
Subset: |
organ_slim uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0004177(hemopoietic organ),UBERON:0005057(immune organ),UBERON:0013765(digestive system element),UBERON:0017672(abdominal viscera) |
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develops_from: | UBERON:0006293(spleen primordium) |
part_of: | UBERON:0000916(abdomen),UBERON:0001007(digestive system),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system) |
Children
is a: | FF:10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL) |
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derives from: | FF:0010025 (human spleen - adult sample),FF:0010044 (human spleen - fetal sample),FF:0011306 (mouse spleen- adult sample),FF:0011360 (mouse spleen- embryo E16 sample),FF:0011417 (mouse spleen- neonate N10 sample),FF:0011430 (mouse spleen- neonate N20 sample),FF:0011491 (mouse spleen- neonate N25 sample),FF:0011517 (mouse spleen-, embryo E18 sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10025-101D7 (spleen, adult, pool1)
- 10044-101F8 (spleen, fetal, pool1)
- 10095-102C5
- 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
- 1271-21F2 (spleen, embryo E18)
- 1354-25G3 (spleen, neonate N25)
- 25-2G2 (spleen, adult)
- 461-43C1 (spleen, embryo E16)
- 752-24D1 (spleen, neonate N10)
- 824-19H1 (spleen, neonate N20)
Mouse (Mus musculus)
- 10025-101D7 (spleen, adult, pool1)
- 10044-101F8 (spleen, fetal, pool1)
- 10095-102C5
- 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
- 1271-21F2 (spleen, embryo E18)
- 1354-25G3 (spleen, neonate N25)
- 25-2G2 (spleen, adult)
- 461-43C1 (spleen, embryo E16)
- 752-24D1 (spleen, neonate N10)
- 824-19H1 (spleen, neonate N20)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002106 (spleen), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
8.98e-131 | FFCP PHASE1:Hg19::chr11:56859584..56859589,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859584..56859589, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:79894790..79894797,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p10@VPS13A |
8.98e-131 | FFCP PHASE1:Hg19::chr4:76901930..76901942,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000501239 |
8.98e-131 | FFCP PHASE2:Hg19::chr10:98014908..98014919,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr10:98014908..98014919, - |
8.98e-131 | FFCP PHASE1:Hg19::chr8:22436248..22436259,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p11@PDLIM2 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:56859608..56859619,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859608..56859619, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:127269434..127269438,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p8@NR5A1 |
8.98e-131 | FFCP PHASE2:Hg19::chr1:28520450..28520453,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p21@PTAFR |
8.98e-131 | FFCP PHASE1:Hg19::chr21:28820954..28820963,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p3@ENST00000420186, p3@uc002ymh.2 |
8.98e-131 | FFCP PHASE2:Hg19::chr8:22424709..22424716,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@ENST00000517384 |
8.98e-131 | FFCP PHASE2:Hg19::chr1:157811772..157811796,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p7@CD5L |
8.98e-131 | FFCP PHASE1:Hg19::chr15:95561320..95561328,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr15:95561320..95561328, - |
8.98e-131 | FFCP PHASE2:Hg19::chr21:28820892..28820899,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p4@ENST00000420186, p4@uc002ymh.2 |
8.98e-131 | FFCP PHASE1:Hg19::chr11:56859603..56859606,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859603..56859606, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:127260615..127260651,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr9:127260615..127260651, - |
8.98e-131 | FFCP PHASE2:Hg19::chr16:84218794..84218800,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr16:84218794..84218800, + |
8.98e-131 | FFCP PHASE1:Hg19::chr6:152639579..152639586,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p60@SYNE1 |
8.98e-131 | FFCP PHASE1:Hg19::chr14:75904485..75904519,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p12@JDP2 |
8.98e-131 | FFCP PHASE2:Hg19::chr10:98014943..98014960,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr10:98014943..98014960, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:133973310..133973321,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p18@AIF1L |
8.98e-131 | FFCP PHASE2:Hg19::chr15:95561320..95561328,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr15:95561320..95561328, - |
8.98e-131 | FFCP PHASE1:Hg19::chr8:47834174..47834213,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000524012 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:56859638..56859643,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859638..56859643, - |
8.98e-131 | FFCP PHASE2:Hg19::chr19:32401253..32401271,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr19:32401253..32401271, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:127269462..127269484,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@NR5A1 |
8.98e-131 | FFCP PHASE1:Hg19::chr1:28520450..28520453,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p21@PTAFR |
8.98e-131 | FFCP PHASE2:Hg19::chr8:22424743..22424759,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000517384 |
8.98e-131 | FFCP PHASE2:Hg19::chrX:69645652..69645664,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p7@GDPD2 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:1891326..1891337,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:1891326..1891337, - |
8.98e-131 | FFCP PHASE1:Hg19::chr1:157811772..157811796,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p7@CD5L |
8.98e-131 | FFCP PHASE1:Hg19::chr10:98014908..98014919,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr10:98014908..98014919, - |
8.98e-131 | FFCP PHASE2:Hg19::chr21:28820911..28820933,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000420186, p1@uc002ymh.2 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:925449..925458,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p17@AP2A2 |
8.98e-131 | FFCP PHASE1:Hg19::chr16:84218794..84218800,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr16:84218794..84218800, + |
8.98e-131 | FFCP PHASE2:Hg19::chr9:127269434..127269438,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p8@NR5A1 |
8.98e-131 | FFCP PHASE1:Hg19::chr11:56859608..56859619,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859608..56859619, - |
8.98e-131 | FFCP PHASE1:Hg19::chr6:119812455..119812476,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@uc003pyn.1 |
8.98e-131 | FFCP PHASE2:Hg19::chr14:75904485..75904519,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p12@JDP2 |
8.98e-131 | FFCP PHASE1:Hg19::chr21:28820892..28820899,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p4@ENST00000420186, p4@uc002ymh.2 |
8.98e-131 | FFCP PHASE2:Hg19::chr9:79894790..79894797,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p10@VPS13A |
8.98e-131 | FFCP PHASE1:Hg19::chr7:22259740..22259751,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p19@RAPGEF5 |
8.98e-131 | FFCP PHASE2:Hg19::chr4:76901930..76901942,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000501239 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:56859693..56859701,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859693..56859701, - |
8.98e-131 | FFCP PHASE1:Hg19::chr9:127269488..127269495,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p5@NR5A1 |
8.98e-131 | FFCP PHASE2:Hg19::chr9:127260615..127260651,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr9:127260615..127260651, - |
8.98e-131 | FFCP PHASE2:Hg19::chr8:22436248..22436259,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p11@PDLIM2 |
8.98e-131 | FFCP PHASE1:Hg19::chr9:124516729..124516752,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr9:124516729..124516752, + |
8.98e-131 | FFCP PHASE1:Hg19::chr19:32401253..32401271,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr19:32401253..32401271, - |
8.98e-131 | FFCP PHASE2:Hg19::chr1:159172187..159172197,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@uc001ftm.1 |
8.98e-131 | FFCP PHASE2:Hg19::chr9:133973310..133973321,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p18@AIF1L |
8.98e-131 | FFCP PHASE1:Hg19::chr10:98014943..98014960,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr10:98014943..98014960, - |
8.98e-131 | FFCP PHASE2:Hg19::chr21:28820941..28820952,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@ENST00000420186, p2@uc002ymh.2 |
8.98e-131 | FFCP PHASE1:Hg19::chr8:22424709..22424716,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@ENST00000517384 |
8.98e-131 | FFCP PHASE2:Hg19::chr17:78171885..78171900,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr17:78171885..78171900, + |
8.98e-131 | FFCP PHASE2:Hg19::chr11:56859584..56859589,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859584..56859589, - |
8.98e-131 | FFCP PHASE2:Hg19::chr9:127269462..127269484,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@NR5A1 |
8.98e-131 | FFCP PHASE1:Hg19::chr11:56859638..56859643,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859638..56859643, - |
8.98e-131 | FFCP PHASE1:Hg19::chr21:28820911..28820933,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000420186, p1@uc002ymh.2 |
8.98e-131 | FFCP PHASE1:Hg19::chr17:78171885..78171900,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr17:78171885..78171900, + |
8.98e-131 | FFCP PHASE1:Hg19::chr11:1891326..1891337,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:1891326..1891337, - |
8.98e-131 | FFCP PHASE2:Hg19::chr6:152639579..152639586,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p60@SYNE1 |
8.98e-131 | FFCP PHASE1:Hg19::chr1:159172187..159172197,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@uc001ftm.1 |
8.98e-131 | FFCP PHASE2:Hg19::chr8:47834174..47834213,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000524012 |
8.98e-131 | FFCP PHASE2:Hg19::chr7:22259740..22259751,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p19@RAPGEF5 |
8.98e-131 | FFCP PHASE2:Hg19::chr21:28820954..28820963,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p3@ENST00000420186, p3@uc002ymh.2 |
8.98e-131 | FFCP PHASE1:Hg19::chr8:22424743..22424759,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@ENST00000517384 |
8.98e-131 | FFCP PHASE1:Hg19::chrX:69645652..69645664,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p7@GDPD2 |
8.98e-131 | FFCP PHASE2:Hg19::chr11:56859603..56859606,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859603..56859606, - |
8.98e-131 | FFCP PHASE2:Hg19::chr9:127269488..127269495,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p5@NR5A1 |
8.98e-131 | FFCP PHASE1:Hg19::chr11:56859693..56859701,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr11:56859693..56859701, - |
8.98e-131 | FFCP PHASE1:Hg19::chr21:28820941..28820952,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p2@ENST00000420186, p2@uc002ymh.2 |
8.98e-131 | FFCP PHASE2:Hg19::chr9:124516729..124516752,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p@chr9:124516729..124516752, + |
8.98e-131 | FFCP PHASE2:Hg19::chr6:119812455..119812476,-#_736a17cfbd40f566fd6df9e82ed4ec5e | p1@uc003pyn.1 |
8.98e-131 | FFCP PHASE1:Hg19::chr11:925449..925458,+#_736a17cfbd40f566fd6df9e82ed4ec5e | p17@AP2A2 |
6.24e-88 | FFCP PHASE1:Hg19::chr11:56859722..56859732,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr11:56859722..56859732, - |
6.24e-88 | FFCP PHASE2:Hg19::chr22:36718586..36718593,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr22:36718586..36718593, - |
6.24e-88 | FFCP PHASE2:Hg19::chr9:127267367..127267383,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr9:127267367..127267383, + |
6.24e-88 | FFCP PHASE2:Hg19::chr4:146461014..146461025,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr4:146461014..146461025, + |
6.24e-88 | FFCP PHASE2:Hg19::chr3:130267501..130267516,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr3:130267501..130267516, + |
6.24e-88 | FFCP PHASE1:Hg19::chr22:36718586..36718593,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr22:36718586..36718593, - |
6.24e-88 | FFCP PHASE2:Hg19::chr1:21011608..21011618,-#_ad33c80427af15cbdae05963c6c52f28 | p15@KIF17 |
6.24e-88 | FFCP PHASE2:Hg19::chr19:32401274..32401289,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr19:32401274..32401289, - |
6.24e-88 | FFCP PHASE1:Hg19::chr1:21011608..21011618,-#_ad33c80427af15cbdae05963c6c52f28 | p15@KIF17 |
6.24e-88 | FFCP PHASE2:Hg19::chr21:40459334..40459341,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr21:40459334..40459341, + |
6.24e-88 | FFCP PHASE2:Hg19::chr11:56859722..56859732,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr11:56859722..56859732, - |
6.24e-88 | FFCP PHASE1:Hg19::chr4:146461014..146461025,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr4:146461014..146461025, + |
6.24e-88 | FFCP PHASE1:Hg19::chr3:130267501..130267516,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr3:130267501..130267516, + |
6.24e-88 | FFCP PHASE1:Hg19::chr9:127267367..127267383,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr9:127267367..127267383, + |
6.24e-88 | FFCP PHASE1:Hg19::chr19:32401274..32401289,-#_ad33c80427af15cbdae05963c6c52f28 | p@chr19:32401274..32401289, - |
6.24e-88 | FFCP PHASE1:Hg19::chr21:40459334..40459341,+#_ad33c80427af15cbdae05963c6c52f28 | p@chr21:40459334..40459341, + |
9.74e-88 | FFCP PHASE2:Hg19::chr2:1508349..1508357,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr2:1508349..1508357, + |
9.74e-88 | FFCP PHASE1:Hg19::chr7:151070957..151070988,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr7:151070957..151070988, + |
9.74e-88 | FFCP PHASE1:Hg19::chr2:128321491..128321509,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr2:128321491..128321509, + |
9.74e-88 | FFCP PHASE2:Hg19::chr16:70680361..70680370,+#_9d693fbafe05dbaa637fb69ee44aa626 | p6@IL34 |
9.74e-88 | FFCP PHASE1:Hg19::chr14:24168655..24168686,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr14:24168655..24168686, + |
9.74e-88 | FFCP PHASE1:Hg19::chr2:1508349..1508357,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr2:1508349..1508357, + |
9.74e-88 | FFCP PHASE2:Hg19::chr12:72481040..72481051,+#_9d693fbafe05dbaa637fb69ee44aa626 | p19@TRHDE |
9.74e-88 | FFCP PHASE1:Hg19::chr12:72481040..72481051,+#_9d693fbafe05dbaa637fb69ee44aa626 | p19@TRHDE |
9.74e-88 | FFCP PHASE2:Hg19::chr2:128321491..128321509,+#_9d693fbafe05dbaa637fb69ee44aa626 | p@chr2:128321491..128321509, + |
9.74e-88 | FFCP PHASE1:Hg19::chr16:70680361..70680370,+#_9d693fbafe05dbaa637fb69ee44aa626 | p6@IL34 |
Property "Property value" (as page type) with input value "UBPROP:0000001 "An organ involved in red blood cell filtration and immune response.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.