UBERON:0003220
From FANTOM5_SSTAR
| Name: | metanephric mesenchyme | ||
|---|---|---|---|
| Definition: | "one of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]" [GO:0072075, Wikipedia:Metanephric_blastema] | ||
| Xrefs: |
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| Synonyms: |
"metanephric blastema" EXACT [Wikipedia:Metanephric_blastema] "metanephric mesoderm" EXACT [Wikipedia:Metanephric_blastema] "metanephrogenic mesenchyme" EXACT [EHDAA:5021] "metanephros associated mesenchyme" EXACT [RETIRED_EHDAA2:0001139] | ||
| Comments: | (TODO - split?) Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0003918(kidney mesenchyme),UBERON:0005291(embryonic tissue),UBERON:0005423(developing anatomical structure) |
|---|---|
| develops_from: | UBERON:0003074(mesonephric duct) |
| part_of: | UBERON:0000922(embryo) |
Children
| develops from: | UBERON:0005749 (glomerular tuft) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003220 (metanephric mesenchyme), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 6.87e-64 | FFCP PHASE1:Hg19::chr2:120409486..120409492,+#_83fbdd50aa28246c64943a7b73e741a4 | p@chr2:120409486..120409492, + |
| 6.87e-64 | FFCP PHASE2:Hg19::chr2:120409486..120409492,+#_83fbdd50aa28246c64943a7b73e741a4 | p@chr2:120409486..120409492, + |
| 9.62e-40 | FFCP PHASE2:Hg19::chr1:94713418..94713436,+#_f61dd9deb140c86304b798a1ed8590f2 | p1@ENST00000413103 |
| 9.62e-40 | FFCP PHASE1:Hg19::chr1:94713418..94713436,+#_f61dd9deb140c86304b798a1ed8590f2 | p1@ENST00000413103 |
| 1.16e-36 | FFCP PHASE1:Hg19::chr17:79426453..79426462,+#_242007d7dd089e48953b9498d685e272 | p@chr17:79426453..79426462, + |
| 1.16e-36 | FFCP PHASE2:Hg19::chr17:79426453..79426462,+#_242007d7dd089e48953b9498d685e272 | p@chr17:79426453..79426462, + |
| 1.31e-36 | FFCP PHASE2:Hg19::chr8:77557753..77557755,-#_9b8421b059f5cc9f547ac1779bb595f3 | p@chr8:77557753..77557755, - |
| 1.31e-36 | FFCP PHASE1:Hg19::chr8:77557753..77557755,-#_9b8421b059f5cc9f547ac1779bb595f3 | p@chr8:77557753..77557755, - |
| 5.58e-32 | FFCP PHASE1:Hg19::chr1:32042764..32042776,+#_a9d6d658b2610bc9acc95798d2540120 | p6@TINAGL1 |
| 5.58e-32 | FFCP PHASE2:Hg19::chr1:32042764..32042776,+#_a9d6d658b2610bc9acc95798d2540120 | p6@TINAGL1 |
| 1.53e-30 | FFCP PHASE2:Hg19::chr15:91416076..91416089,+#_b0b380dd4acffeded930fd2c4705dc5a | p9@FURIN |
| 1.53e-30 | FFCP PHASE1:Hg19::chr15:91416076..91416089,+#_b0b380dd4acffeded930fd2c4705dc5a | p9@FURIN |
| 3.83e-30 | FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_0cea42b886dafd88d2d03dbbc5d7bc3f | p7@LRRN4 |
| 3.83e-30 | FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_0cea42b886dafd88d2d03dbbc5d7bc3f | p7@LRRN4 |
| 1.78e-29 | FFCP PHASE1:Hg19::chr1:42777312..42777314,+#_61d080117ee6d846ad35c8f7305bdab0 | p@chr1:42777312..42777314, + |
| 1.78e-29 | FFCP PHASE1:Hg19::chr2:26700984..26700993,-#_61d080117ee6d846ad35c8f7305bdab0 | p7@OTOF |
| 1.78e-29 | FFCP PHASE1:Hg19::chr6:18225523..18225534,-#_61d080117ee6d846ad35c8f7305bdab0 | p@chr6:18225523..18225534, - |
| 1.78e-29 | FFCP PHASE2:Hg19::chr22:47030082..47030087,+#_61d080117ee6d846ad35c8f7305bdab0 | p@chr22:47030082..47030087, + |
| 1.78e-29 | FFCP PHASE1:Hg19::chr2:26700331..26700340,-#_61d080117ee6d846ad35c8f7305bdab0 | p@chr2:26700331..26700340, - |
| 1.78e-29 | FFCP PHASE2:Hg19::chr1:42777312..42777314,+#_61d080117ee6d846ad35c8f7305bdab0 | p@chr1:42777312..42777314, + |
| 1.78e-29 | FFCP PHASE1:Hg19::chr22:47030082..47030087,+#_61d080117ee6d846ad35c8f7305bdab0 | p@chr22:47030082..47030087, + |
| 1.78e-29 | FFCP PHASE2:Hg19::chr2:26700984..26700993,-#_61d080117ee6d846ad35c8f7305bdab0 | p7@OTOF |
| 1.78e-29 | FFCP PHASE2:Hg19::chr6:18225523..18225534,-#_61d080117ee6d846ad35c8f7305bdab0 | p@chr6:18225523..18225534, - |
| 1.78e-29 | FFCP PHASE2:Hg19::chr2:26700331..26700340,-#_61d080117ee6d846ad35c8f7305bdab0 | p@chr2:26700331..26700340, - |
| 7.96e-27 | FFCP PHASE1:Hg19::chr10:3477893..3477912,-#_d65391cd0b34520e30a59f1b535dfdc7 | p@chr10:3477893..3477912, - |
| 7.96e-27 | FFCP PHASE2:Hg19::chr10:3477893..3477912,-#_d65391cd0b34520e30a59f1b535dfdc7 | p@chr10:3477893..3477912, - |
| 6.29e-26 | FFCP PHASE2:Hg19::chr1:172926077..172926120,-#_c4a052724237ae191817d48dab549295 | p@chr1:172926077..172926120, - |
| 6.29e-26 | FFCP PHASE1:Hg19::chr1:172926077..172926120,-#_c4a052724237ae191817d48dab549295 | p@chr1:172926077..172926120, - |
| 6.32e-26 | FFCP PHASE2:Hg19::chrX:128782722..128782738,-#_9d28d90b5d2d18211db240b600309ca3 | p5@APLN |
| 6.32e-26 | FFCP PHASE1:Hg19::chrX:128782722..128782738,-#_9d28d90b5d2d18211db240b600309ca3 | p5@APLN |
| 9.89e-26 | FFCP PHASE2:Hg19::chr2:693380..693398,+#_99035b83d5ef3fbb9f0b4873286697ca | p@chr2:693380..693398, + |
| 9.89e-26 | FFCP PHASE1:Hg19::chr2:693380..693398,+#_99035b83d5ef3fbb9f0b4873286697ca | p@chr2:693380..693398, + |
| 1.28e-23 | FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_cb1d7883b6785364ac75793d54260e34 | p@chr2:133426030..133426041, - |
| 1.28e-23 | FFCP PHASE1:Hg19::chr6:84849252..84849259,+#_cb1d7883b6785364ac75793d54260e34 | p@chr6:84849252..84849259, + |
| 1.28e-23 | FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_cb1d7883b6785364ac75793d54260e34 | p@chr2:133426030..133426041, - |
| 1.28e-23 | FFCP PHASE2:Hg19::chr6:84849252..84849259,+#_cb1d7883b6785364ac75793d54260e34 | p@chr6:84849252..84849259, + |
| 1.44e-23 | FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_b1c0a3dea8de09f944818ab03c813d5b | p23@TTC39A |
| 1.44e-23 | FFCP PHASE1:Hg19::chr7:28998254..28998261,-#_b1c0a3dea8de09f944818ab03c813d5b | p10@TRIL |
| 1.44e-23 | FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_b1c0a3dea8de09f944818ab03c813d5b | p23@TTC39A |
| 1.44e-23 | FFCP PHASE2:Hg19::chr7:28998254..28998261,-#_b1c0a3dea8de09f944818ab03c813d5b | p10@TRIL |
| 1.61e-23 | FFCP PHASE1:Hg19::chr15:85403302..85403304,+#_1097f8da36fd4b36e3fe0eafba66e28b | p@chr15:85403302..85403304, + |
| 1.61e-23 | FFCP PHASE2:Hg19::chr7:4051097..4051112,+#_1097f8da36fd4b36e3fe0eafba66e28b | p@chr7:4051097..4051112, + |
| 1.61e-23 | FFCP PHASE2:Hg19::chr15:85403302..85403304,+#_1097f8da36fd4b36e3fe0eafba66e28b | p@chr15:85403302..85403304, + |
| 1.61e-23 | FFCP PHASE1:Hg19::chr7:4051097..4051112,+#_1097f8da36fd4b36e3fe0eafba66e28b | p@chr7:4051097..4051112, + |
| 1.8e-23 | FFCP PHASE1:Hg19::chr16:2141529..2141537,+#_f765763d12619d34cac7b13b2eefd615 | p@chr16:2141529..2141537, + |
| 1.8e-23 | FFCP PHASE2:Hg19::chr16:2141529..2141537,+#_f765763d12619d34cac7b13b2eefd615 | p@chr16:2141529..2141537, + |
| 2.92e-22 | FFCP PHASE2:Hg19::chr5:74244100..74244117,+#_1e7be0377b507e255ae825f176576a61 | p@chr5:74244100..74244117, + |
| 2.92e-22 | FFCP PHASE1:Hg19::chr5:74244100..74244117,+#_1e7be0377b507e255ae825f176576a61 | p@chr5:74244100..74244117, + |
| 5.69e-22 | FFCP PHASE2:Hg19::chr5:148651758..148651769,-#_33e13c431f0984d1bac4d3fef37a0932 | p@chr5:148651758..148651769, - |
| 5.69e-22 | FFCP PHASE1:Hg19::chr5:148651758..148651769,-#_33e13c431f0984d1bac4d3fef37a0932 | p@chr5:148651758..148651769, - |
| 2.9e-21 | FFCP PHASE1:Hg19::chr16:86768403..86768437,+#_7579a79a0657d3da8f7fad7dd7db47a7 | p@chr16:86768403..86768437, + |
| 2.9e-21 | FFCP PHASE2:Hg19::chr16:86768403..86768437,+#_7579a79a0657d3da8f7fad7dd7db47a7 | p@chr16:86768403..86768437, + |
| 4.78e-21 | FFCP PHASE1:Hg19::chr17:2076002..2076026,-#_8ea946546a3dafdb6c52b3fdf4c1d5aa | p@chr17:2076002..2076026, - |
| 4.78e-21 | FFCP PHASE2:Hg19::chr17:2076002..2076026,-#_8ea946546a3dafdb6c52b3fdf4c1d5aa | p@chr17:2076002..2076026, - |
| 1.26e-20 | FFCP PHASE1:Hg19::chr1:32712897..32712909,+#_061cfa58210f9d27f27c8a2eb285cc27 | p3@FAM167B |
| 1.26e-20 | FFCP PHASE2:Hg19::chr1:32712897..32712909,+#_061cfa58210f9d27f27c8a2eb285cc27 | p3@FAM167B |
| 2.32e-20 | FFCP PHASE2:Hg19::chr11:124628392..124628427,-#_ef77d6a63eec4d6e8a69c4989ff3d74e | p@chr11:124628392..124628427, - |
| 2.32e-20 | FFCP PHASE1:Hg19::chr11:124628392..124628427,-#_ef77d6a63eec4d6e8a69c4989ff3d74e | p@chr11:124628392..124628427, - |
| 3.42e-20 | FFCP PHASE2:Hg19::chr3:98591021..98591026,-#_d5a174b9a8ee15113d09b51a0705cce1 | p1@ENST00000487339 |
| 3.42e-20 | FFCP PHASE1:Hg19::chr3:98591021..98591026,-#_d5a174b9a8ee15113d09b51a0705cce1 | p1@ENST00000487339 |
| 3.44e-20 | FFCP PHASE1:Hg19::chr19:47231340..47231383,-#_ea8a6372a3b45c769139fda13d8b11df | p@chr19:47231340..47231383, - |
| 3.44e-20 | FFCP PHASE2:Hg19::chr19:47231340..47231383,-#_ea8a6372a3b45c769139fda13d8b11df | p@chr19:47231340..47231383, - |
| 3.58e-20 | FFCP PHASE1:Hg19::chr19:1826957..1826984,-#_6bee355fcfa6fb9f81055f3de720bc43 | p@chr19:1826957..1826984, - |
| 3.58e-20 | FFCP PHASE2:Hg19::chr19:1826957..1826984,-#_6bee355fcfa6fb9f81055f3de720bc43 | p@chr19:1826957..1826984, - |
| 4.39e-20 | FFCP PHASE1:Hg19::chr4:38057595..38057624,-#_8a3d967c4ebe7f8fb843186be157e412 | p@chr4:38057595..38057624, - |
| 4.39e-20 | FFCP PHASE2:Hg19::chr4:38057595..38057624,-#_8a3d967c4ebe7f8fb843186be157e412 | p@chr4:38057595..38057624, - |
| 7.13e-20 | FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_3dd84c408042616daab393f71bd230c0 | p@chr2:133426106..133426117, - |
| 7.13e-20 | FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_3dd84c408042616daab393f71bd230c0 | p@chr2:133426106..133426117, - |
| 7.84e-20 | FFCP PHASE1:Hg19::chr15:36653709..36653720,-#_34495f8c314905b90e8f6a3c427d547a | p@chr15:36653709..36653720, - |
| 7.84e-20 | FFCP PHASE2:Hg19::chr15:36653709..36653720,-#_34495f8c314905b90e8f6a3c427d547a | p@chr15:36653709..36653720, - |
| 7.84e-20 | FFCP PHASE1:Hg19::chr9:35753821..35753835,-#_34495f8c314905b90e8f6a3c427d547a | p@chr9:35753821..35753835, - |
| 7.84e-20 | FFCP PHASE2:Hg19::chr9:35753821..35753835,-#_34495f8c314905b90e8f6a3c427d547a | p@chr9:35753821..35753835, - |
| 8.62e-20 | FFCP PHASE1:Hg19::chr4:145568170..145568180,-#_b0fe8ff306090608f34b2a25fa37b182 | p@chr4:145568170..145568180, - |
| 8.62e-20 | FFCP PHASE2:Hg19::chr4:145568170..145568180,-#_b0fe8ff306090608f34b2a25fa37b182 | p@chr4:145568170..145568180, - |
| 1.04e-19 | FFCP PHASE2:Hg19::chr19:38397228..38397266,-#_7e7926b1882e8e13d34947dd1ab9ce0c | p1@WDR87 |
| 1.04e-19 | FFCP PHASE1:Hg19::chr19:38397228..38397266,-#_7e7926b1882e8e13d34947dd1ab9ce0c | p1@WDR87 |
| 1.15e-19 | FFCP PHASE1:Hg19::chr14:91270270..91270281,-#_860289b8eeae157ffa3d34f17d73443b | p@chr14:91270270..91270281, - |
| 1.15e-19 | FFCP PHASE2:Hg19::chr14:91270270..91270281,-#_860289b8eeae157ffa3d34f17d73443b | p@chr14:91270270..91270281, - |
| 2.44e-19 | FFCP PHASE2:Hg19::chr12:52306196..52306215,+#_373facf1a6ce48b6e5c4d1acb157fbf3 | p6@ACVRL1 |
| 2.44e-19 | FFCP PHASE1:Hg19::chr12:52306196..52306215,+#_373facf1a6ce48b6e5c4d1acb157fbf3 | p6@ACVRL1 |
| 3.27e-19 | FFCP PHASE2:Hg19::chr3:43538305..43538325,-#_051a2e5a8ab09c3e0e613d0b51398d19 | p@chr3:43538305..43538325, - |
| 3.27e-19 | FFCP PHASE1:Hg19::chr3:43538305..43538325,-#_051a2e5a8ab09c3e0e613d0b51398d19 | p@chr3:43538305..43538325, - |
| 4.64e-19 | FFCP PHASE1:Hg19::chr17:171147..171161,+#_de9bd875f915a6529f82614196b0c762 | p@chr17:171147..171161, + |
| 4.64e-19 | FFCP PHASE2:Hg19::chr17:171147..171161,+#_de9bd875f915a6529f82614196b0c762 | p@chr17:171147..171161, + |
| 5.39e-19 | FFCP PHASE1:Hg19::chr1:22211913..22211920,+#_39bc24fa0b10d6721ce0f026fb9a9f1a | p@chr1:22211913..22211920, + |
| 5.39e-19 | FFCP PHASE2:Hg19::chr1:22211913..22211920,+#_39bc24fa0b10d6721ce0f026fb9a9f1a | p@chr1:22211913..22211920, + |
| 1.99e-18 | FFCP PHASE1:Hg19::chr7:27219833..27219845,-#_22edc03dbd9df99edd658866653dabf8 | p7@HOXA10 |
| 1.99e-18 | FFCP PHASE2:Hg19::chr7:27219833..27219845,-#_22edc03dbd9df99edd658866653dabf8 | p7@HOXA10 |
| 2.69e-18 | FFCP PHASE2:Hg19::chr1:32041957..32041990,+#_b0317e690e1e1f690dcb8665fc489840 | p3@TINAGL1 |
| 2.69e-18 | FFCP PHASE1:Hg19::chr1:32041957..32041990,+#_b0317e690e1e1f690dcb8665fc489840 | p3@TINAGL1 |
| 4.1e-18 | FFCP PHASE2:Hg19::chr6:132270228..132270243,-#_f096c64b8a07c169fcc5f8e9783b1d59 | p17@CTGF |
| 4.1e-18 | FFCP PHASE1:Hg19::chr6:132270228..132270243,-#_f096c64b8a07c169fcc5f8e9783b1d59 | p17@CTGF |
| 5.7e-18 | FFCP PHASE2:Hg19::chr11:940729..940745,+#_253aa156180f1f6fcc09117941102095 | p5@AP2A2 |
| 5.7e-18 | FFCP PHASE1:Hg19::chr11:940729..940745,+#_253aa156180f1f6fcc09117941102095 | p5@AP2A2 |
| 6.5e-18 | FFCP PHASE2:Hg19::chr19:42007093..42007107,-#_7fb83aa92c4c2eb54544e5fe8d5faf6d | p@chr19:42007093..42007107, - |
| 6.5e-18 | FFCP PHASE1:Hg19::chr19:42007093..42007107,-#_7fb83aa92c4c2eb54544e5fe8d5faf6d | p@chr19:42007093..42007107, - |
| 6.99e-18 | FFCP PHASE2:Hg19::chrX:128781853..128781866,-#_d327f6b4c642c13def5477aae2f9bca5 | p@chrX:128781853..128781866, - |
| 6.99e-18 | FFCP PHASE1:Hg19::chrX:128781853..128781866,-#_d327f6b4c642c13def5477aae2f9bca5 | p@chrX:128781853..128781866, - |
| 1.24e-17 | FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_ade0482471a0b266b3d32a5232d5b6e4 | p@chr16:86604624..86604648, + |
| 1.24e-17 | FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_ade0482471a0b266b3d32a5232d5b6e4 | p@chr16:86604624..86604648, + |
