UBERON:0001777
From FANTOM5_SSTAR
| Name: | substantia propria of cornea | ||
|---|---|---|---|
| Definition: | "The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamellﾃｦ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamellﾃｦ interweaving more than posterior lamellﾃｦ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamellﾃｦ. The lamellﾃｦ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamellﾃｦ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma] | ||
| Xrefs: |
| ||
| Synonyms: |
"corneal stroma" EXACT [] "stroma of cornea" EXACT [] "substantia propria" RELATED [] | ||
| Comments: | This class was created automatically from a combination of ontologies | ||
| Alt_id: | UBERON:FMA_58306-MA_0001245 | ||
| Subset: |
uberon_slim vertebrate_core |
200px-Gray871.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0003566(head connective tissue),UBERON:0003891(stroma),UBERON:0004121(ectoderm-derived structure) |
|---|---|
| part_of: | UBERON:0000964(cornea) |
Children
| part of: | CL:0002363 (keratocyte) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11527-119I6 (Keratocytes, donor1)
- 11607-120I5 (Keratocytes, donor2)
- 11688-122I5 (Keratocytes, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.55e-98 | FFCP PHASE2:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85ea | p@chr7:150910973..150910976, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85ea | p@chr7:150910973..150910976, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85ea | p@chr3:52362029..52362031, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85ea | p@chr3:52362029..52362031, + |
| 4.52e-50 | FFCP PHASE2:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369d | p8@HTR7 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369d | p@chr6:113369869..113369877, + |
| 4.52e-50 | FFCP PHASE2:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369d | p16@SHC4 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369d | p5@ENST00000520840, p5@ENST00000523806 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369d | p8@HTR7 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369d | p5@ENST00000520840, p5@ENST00000523806 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369d | p16@SHC4 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369d | p@chr6:113369869..113369877, + |
| 5.04e-34 | FFCP PHASE1:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928 | p@chr6:151770193..151770196, - |
| 5.04e-34 | FFCP PHASE2:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928 | p@chr21:47410794..47410799, + |
| 5.04e-34 | FFCP PHASE1:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928 | p10@ERI3 |
| 5.04e-34 | FFCP PHASE1:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928 | p@chr21:47410794..47410799, + |
| 5.04e-34 | FFCP PHASE2:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928 | p10@ERI3 |
| 5.04e-34 | FFCP PHASE2:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928 | p@chr6:151770193..151770196, - |
| 7.05e-34 | FFCP PHASE2:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9 | p@chr5:79375654..79375674, + |
| 7.05e-34 | FFCP PHASE1:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:43133595..43133606, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9 | p4@POMC |
| 7.05e-34 | FFCP PHASE1:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9 | p14@CTNNBIP1 |
| 7.05e-34 | FFCP PHASE1:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:74020629..74020634, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9 | p@chr5:79375654..79375674, + |
| 7.05e-34 | FFCP PHASE2:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9 | p2@ENST00000560068 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9 | p19@MALAT1 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9 | p4@POMC |
| 7.05e-34 | FFCP PHASE2:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:43133595..43133606, - |
| 7.05e-34 | FFCP PHASE2:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9 | p14@CTNNBIP1 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:74020629..74020634, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9 | p19@MALAT1 |
| 7.05e-34 | FFCP PHASE1:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9 | p2@ENST00000560068 |
| 6.41e-31 | FFCP PHASE1:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191f | p1@ENST00000503456 |
| 6.41e-31 | FFCP PHASE2:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191f | p1@ENST00000503456 |
| 4.55e-29 | FFCP PHASE2:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49 | p26@SH3KBP1 |
| 4.55e-29 | FFCP PHASE1:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49 | p26@SH3KBP1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr15:90344775..90344794, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@TMED5 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr11:34073641..34073656, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr20:60758060..60758074, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr1:151171326..151171337, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr2:219540880..219540912, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:6049190..6049209, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr4:120546882..120546885, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@AXDND1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@ADAMTS3 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr3:9956047..9956079, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47397571..47397582, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p4@AB383919 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p2@CU687581 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:6049190..6049209, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47681190..47681194, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr16:10590513..10590515, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p9@FAM190B |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p18@HOPX |
| 9.18e-26 | FFCP PHASE1:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr11:34073641..34073656, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@C17orf79 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@TMED5 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr15:90344775..90344794, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:100806199..100806216, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr20:60758060..60758074, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr2:219540880..219540912, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr4:120546882..120546885, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:100806199..100806216, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@AXDND1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr3:9956047..9956079, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47397571..47397582, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr1:151171326..151171337, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p4@AB383919 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p18@HOPX |
| 9.18e-26 | FFCP PHASE1:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr16:10590513..10590515, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47681190..47681194, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@ADAMTS3 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p9@FAM190B |
| 9.18e-26 | FFCP PHASE2:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@C17orf79 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p2@CU687581 |
| 6.02e-24 | FFCP PHASE1:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6 | p3@NUDT17 |
| 6.02e-24 | FFCP PHASE2:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6 | p3@NUDT17 |
| 3.81e-21 | FFCP PHASE1:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3e | p13@ALDH3A1 |
| 3.81e-21 | FFCP PHASE2:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3e | p13@ALDH3A1 |
| 4.66e-21 | FFCP PHASE2:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07 | p16@FOXP4 |
| 4.66e-21 | FFCP PHASE1:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07 | p16@FOXP4 |
| 4.66e-21 | FFCP PHASE2:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07 | p@chr4:52917466..52917498, - |
| 4.66e-21 | FFCP PHASE1:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07 | p@chr4:52917466..52917498, - |
| 5.7e-21 | FFCP PHASE2:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646b | p@chr12:58141331..58141342, + |
| 5.7e-21 | FFCP PHASE2:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646b | p29@ARHGAP26 |
| 5.7e-21 | FFCP PHASE1:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646b | p@chr12:58141331..58141342, + |
| 5.7e-21 | FFCP PHASE1:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646b | p29@ARHGAP26 |
| 5.7e-21 | FFCP PHASE2:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646b | p3@STX1A |
| 5.7e-21 | FFCP PHASE1:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646b | p14@EHD2 |
| 5.7e-21 | FFCP PHASE1:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646b | p3@STX1A |
| 5.7e-21 | FFCP PHASE2:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646b | p@chr8:27686258..27686262, - |
| 5.7e-21 | FFCP PHASE2:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646b | p14@EHD2 |
| 5.7e-21 | FFCP PHASE1:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646b | p@chr8:27686258..27686262, - |
| 6.96e-21 | FFCP PHASE2:Hg19::chr12:102455905..102455915,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p5@CCDC53 |
| 6.96e-21 | FFCP PHASE1:Hg19::chr17:53803029..53803034,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr17:53803029..53803034, - |
| 6.96e-21 | FFCP PHASE2:Hg19::chr2:37898966..37898999,+#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr2:37898966..37898999, + |
| 6.96e-21 | FFCP PHASE2:Hg19::chr17:45144823..45144834,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr17:45144823..45144834, - |
| 6.96e-21 | FFCP PHASE1:Hg19::chr5:6766044..6766055,+#_3b19ef7bdbfd9a808b1be5d581addf21 | p2@ENST00000506093 |
| 6.96e-21 | FFCP PHASE1:Hg19::chr19:893600..893603,+#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr19:893600..893603, + |
