Novel motif:4

name:	motif4_TGTCTA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	1.061427e-40
GO:0051716	cellular response to stimulus	3.597545e-26
GO:0007154	cell communication	6.114364e-23
GO:0023052	signaling	7.250907e-23
GO:0007275	multicellular organismal development	7.586837e-23
GO:0032502	developmental process	1.593986e-22
GO:0032501	multicellular organismal process	8.779185e-22
GO:0048513	organ development	2.338620e-21
GO:0007165	signal transduction	3.054254e-21
GO:0042221	response to chemical stimulus	1.731005e-20
GO:2000191	regulation of fatty acid transport	2.211606e-20
GO:0009628	response to abiotic stimulus	1.067967e-19
GO:2000026	regulation of multicellular organismal development	1.966766e-19
GO:0048731	system development	4.252886e-19
GO:0051592	response to calcium ion	5.560645e-19
GO:0050793	regulation of developmental process	1.366845e-18
GO:0048856	anatomical structure development	1.526914e-18
GO:0009266	response to temperature stimulus	1.873171e-18
GO:0019220	regulation of phosphate metabolic process	2.470122e-18
GO:0001932	regulation of protein phosphorylation	1.143521e-17
GO:0042325	regulation of phosphorylation	1.357269e-17
GO:0009408	response to heat	1.971436e-17
GO:0051239	regulation of multicellular organismal process	4.074564e-17
GO:0010038	response to metal ion	1.013005e-16
GO:0006950	response to stress	2.249493e-16
GO:0006955	immune response	2.767434e-16
GO:0009888	tissue development	5.391328e-16
GO:0034605	cellular response to heat	6.034910e-16
GO:0031399	regulation of protein modification process	7.019878e-16
GO:0048583	regulation of response to stimulus	1.026758e-15
GO:0002688	regulation of leukocyte chemotaxis	1.125403e-15
GO:0007166	cell surface receptor linked signaling pathway	1.649979e-15
GO:0002690	positive regulation of leukocyte chemotaxis	1.928044e-15
GO:0002604	regulation of dendritic cell antigen processing and presentation	2.068993e-15
GO:0042060	wound healing	2.480393e-15
GO:0001775	cell activation	2.851787e-15
GO:0032103	positive regulation of response to external stimulus	3.374052e-15
GO:0016525	negative regulation of angiogenesis	3.465216e-15
GO:0045765	regulation of angiogenesis	3.981083e-15
GO:0002577	regulation of antigen processing and presentation	4.201400e-15
GO:0030168	platelet activation	7.288722e-15
GO:0002576	platelet degranulation	7.672589e-15
GO:0007155	cell adhesion	1.226087e-14
GO:0002376	immune system process	1.618628e-14
GO:0032890	regulation of organic acid transport	1.888422e-14
GO:0043549	regulation of kinase activity	2.284509e-14
GO:0006916	anti-apoptosis	2.953941e-14
GO:0032940	secretion by cell	3.861491e-14
GO:0010627	regulation of intracellular protein kinase cascade	3.949620e-14
GO:0007596	blood coagulation	6.524004e-14
GO:0010758	regulation of macrophage chemotaxis	7.160672e-14
GO:0045859	regulation of protein kinase activity	7.981059e-14
GO:0007599	hemostasis	1.589309e-13
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	1.642438e-13
GO:0051338	regulation of transferase activity	2.083331e-13
GO:0006887	exocytosis	2.328222e-13
GO:0009611	response to wounding	2.338467e-13
GO:0002687	positive regulation of leukocyte migration	2.689433e-13
GO:0046903	secretion	2.838259e-13
GO:0061041	regulation of wound healing	2.923303e-13
GO:0010759	positive regulation of macrophage chemotaxis	3.518336e-13
GO:0010648	negative regulation of cell communication	3.977773e-13
GO:0023057	negative regulation of signaling	6.520186e-13
GO:0032308	positive regulation of prostaglandin secretion	9.811957e-13
GO:0002685	regulation of leukocyte migration	1.062066e-12
GO:0002544	chronic inflammatory response	1.313304e-12
GO:0009968	negative regulation of signal transduction	1.590255e-12
GO:0042327	positive regulation of phosphorylation	1.603656e-12
GO:0043030	regulation of macrophage activation	1.608909e-12
GO:0048520	positive regulation of behavior	1.611596e-12
GO:0071675	regulation of mononuclear cell migration	1.616904e-12
GO:0030193	regulation of blood coagulation	1.942715e-12
GO:0003008	system process	2.081106e-12
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2.123896e-12
GO:0009966	regulation of signal transduction	3.254396e-12
GO:0043406	positive regulation of MAP kinase activity	3.522139e-12
GO:0043405	regulation of MAP kinase activity	3.593676e-12
GO:0045937	positive regulation of phosphate metabolic process	4.116823e-12
GO:0050921	positive regulation of chemotaxis	4.301128e-12
GO:0048585	negative regulation of response to stimulus	5.284662e-12
GO:2000193	positive regulation of fatty acid transport	5.459047e-12
GO:0010757	negative regulation of plasminogen activation	6.032430e-12
GO:0000187	activation of MAPK activity	7.259538e-12
GO:0071622	regulation of granulocyte chemotaxis	7.733129e-12
GO:0007417	central nervous system development	1.036696e-11
GO:0032844	regulation of homeostatic process	1.378270e-11
GO:0010740	positive regulation of intracellular protein kinase cascade	1.380986e-11
GO:0070163	regulation of adiponectin secretion	1.412346e-11
GO:0032722	positive regulation of chemokine production	1.445860e-11
GO:0050818	regulation of coagulation	2.418166e-11
GO:0065008	regulation of biological quality	2.461252e-11
GO:0032268	regulation of cellular protein metabolic process	2.571795e-11
GO:0010193	response to ozone	2.793654e-11
GO:0050790	regulation of catalytic activity	2.930764e-11
GO:0022603	regulation of anatomical structure morphogenesis	2.936323e-11
GO:0010755	regulation of plasminogen activation	3.136189e-11
GO:0050878	regulation of body fluid levels	3.197859e-11
GO:0032642	regulation of chemokine production	3.284939e-11
GO:0010751	negative regulation of nitric oxide mediated signal transduction	3.315566e-11
GO:0043652	engulfment of apoptotic cell	3.315566e-11
GO:0010754	negative regulation of cGMP-mediated signaling	3.315566e-11
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	3.315566e-11
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.315566e-11
GO:0048739	cardiac muscle fiber development	3.342788e-11
GO:0051606	detection of stimulus	3.482675e-11
GO:0042346	positive regulation of NF-kappaB import into nucleus	3.734943e-11
GO:0009743	response to carbohydrate stimulus	3.757862e-11
GO:0032101	regulation of response to external stimulus	3.782758e-11
GO:0050794	regulation of cellular process	4.273739e-11
GO:0050789	regulation of biological process	4.324108e-11
GO:0032892	positive regulation of organic acid transport	4.720963e-11
GO:0010646	regulation of cell communication	5.255238e-11
GO:0001714	endodermal cell fate specification	5.509778e-11
GO:0070164	negative regulation of adiponectin secretion	5.511256e-11
GO:0060355	positive regulation of cell adhesion molecule production	5.511256e-11
GO:0035505	positive regulation of myosin light chain kinase activity	5.511256e-11
GO:0050920	regulation of chemotaxis	6.355077e-11
GO:0050865	regulation of cell activation	6.709112e-11
GO:0009746	response to hexose stimulus	6.867589e-11
GO:0051093	negative regulation of developmental process	7.264681e-11
GO:0002684	positive regulation of immune system process	8.041211e-11
GO:0048584	positive regulation of response to stimulus	9.641215e-11
GO:0006952	defense response	1.170585e-10
GO:0050974	detection of mechanical stimulus involved in sensory perception	1.233639e-10
GO:0010955	negative regulation of protein processing	1.250805e-10
GO:0008285	negative regulation of cell proliferation	1.283534e-10
GO:0010033	response to organic substance	1.342809e-10
GO:0034284	response to monosaccharide stimulus	1.393132e-10
GO:0051246	regulation of protein metabolic process	1.415587e-10
GO:0009581	detection of external stimulus	1.459111e-10
GO:0050877	neurological system process	1.783992e-10
GO:0001660	fever generation	2.046312e-10
GO:0042552	myelination	2.063644e-10
GO:0055082	cellular chemical homeostasis	2.149299e-10
GO:0071902	positive regulation of protein serine/threonine kinase activity	2.150059e-10
GO:0001936	regulation of endothelial cell proliferation	2.457892e-10
GO:0048468	cell development	2.515030e-10
GO:0051707	response to other organism	2.760694e-10
GO:0010574	regulation of vascular endothelial growth factor production	2.972619e-10
GO:0071900	regulation of protein serine/threonine kinase activity	3.379921e-10
GO:0010035	response to inorganic substance	3.438201e-10
GO:0045595	regulation of cell differentiation	3.523145e-10
GO:0051240	positive regulation of multicellular organismal process	3.569475e-10
GO:0080134	regulation of response to stress	3.615820e-10
GO:0010470	regulation of gastrulation	3.625572e-10
GO:0002694	regulation of leukocyte activation	3.631835e-10
GO:0050982	detection of mechanical stimulus	3.876680e-10
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	4.109981e-10
GO:0009653	anatomical structure morphogenesis	4.186336e-10
GO:0045410	positive regulation of interleukin-6 biosynthetic process	4.254350e-10
GO:0002696	positive regulation of leukocyte activation	4.527553e-10
GO:0010647	positive regulation of cell communication	5.197613e-10
GO:0033591	response to L-ascorbic acid	5.227847e-10
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	5.272209e-10
GO:0048869	cellular developmental process	5.739876e-10
GO:0050795	regulation of behavior	6.085000e-10
GO:0045860	positive regulation of protein kinase activity	6.151485e-10
GO:0045766	positive regulation of angiogenesis	7.660905e-10
GO:0032655	regulation of interleukin-12 production	8.490838e-10
GO:0023051	regulation of signaling	8.873949e-10
GO:0090287	regulation of cellular response to growth factor stimulus	8.918242e-10
GO:0034762	regulation of transmembrane transport	9.509062e-10
GO:0009749	response to glucose stimulus	9.680656e-10
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	1.003652e-9
GO:0065007	biological regulation	1.042752e-9
GO:0023056	positive regulation of signaling	1.067855e-9
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.158781e-9
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.201168e-9
GO:0070887	cellular response to chemical stimulus	1.310731e-9
GO:0051409	response to nitrosative stress	1.327040e-9
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.336469e-9
GO:0035556	intracellular signal transduction	1.364425e-9
GO:0014866	skeletal myofibril assembly	1.382397e-9
GO:0050771	negative regulation of axonogenesis	1.425294e-9
GO:0071322	cellular response to carbohydrate stimulus	1.438368e-9
GO:0050867	positive regulation of cell activation	1.504974e-9
GO:0000165	MAPKKK cascade	1.635822e-9
GO:0033674	positive regulation of kinase activity	1.708527e-9
GO:0009967	positive regulation of signal transduction	1.867643e-9
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	2.169582e-9
GO:0051704	multi-organism process	2.248991e-9
GO:0001678	cellular glucose homeostasis	2.338464e-9
GO:0050776	regulation of immune response	2.451815e-9
GO:0065009	regulation of molecular function	2.590944e-9
GO:0072507	divalent inorganic cation homeostasis	2.690544e-9
GO:0006873	cellular ion homeostasis	2.747608e-9
GO:0072503	cellular divalent inorganic cation homeostasis	3.170381e-9
GO:0002682	regulation of immune system process	3.479470e-9
GO:0055074	calcium ion homeostasis	3.560229e-9
GO:0006874	cellular calcium ion homeostasis	3.791328e-9
GO:0018149	peptide cross-linking	3.914503e-9
GO:0071333	cellular response to glucose stimulus	3.941247e-9
GO:0045080	positive regulation of chemokine biosynthetic process	4.343379e-9
GO:2000758	positive regulation of peptidyl-lysine acetylation	4.777310e-9
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	4.886754e-9
GO:0048519	negative regulation of biological process	5.092369e-9
GO:0001937	negative regulation of endothelial cell proliferation	5.294768e-9
GO:0030154	cell differentiation	5.346841e-9
GO:0050801	ion homeostasis	5.696527e-9
GO:0032914	positive regulation of transforming growth factor beta1 production	6.042289e-9
GO:0071822	protein complex subunit organization	6.739266e-9
GO:0010596	negative regulation of endothelial cell migration	6.821681e-9
GO:0035234	germ cell programmed cell death	6.952561e-9
GO:0035691	macrophage migration inhibitory factor signaling pathway	7.325172e-9
GO:0010332	response to gamma radiation	8.058762e-9
GO:0019228	regulation of action potential in neuron	8.195587e-9
GO:0051480	cytosolic calcium ion homeostasis	8.716072e-9
GO:0043032	positive regulation of macrophage activation	8.732179e-9
GO:0007076	mitotic chromosome condensation	8.913425e-9
GO:0022402	cell cycle process	9.288223e-9
GO:0060548	negative regulation of cell death	9.519037e-9
GO:0030241	skeletal muscle myosin thick filament assembly	9.984772e-9
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.028482e-8
GO:0007186	G-protein coupled receptor protein signaling pathway	1.041895e-8
GO:0060412	ventricular septum morphogenesis	1.055326e-8
GO:0040011	locomotion	1.075411e-8
GO:0001711	endodermal cell fate commitment	1.094738e-8
GO:0051895	negative regulation of focal adhesion assembly	1.162126e-8
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	1.203873e-8
GO:0009607	response to biotic stimulus	1.260342e-8
GO:0032755	positive regulation of interleukin-6 production	1.260906e-8
GO:0030155	regulation of cell adhesion	1.261840e-8
GO:0043277	apoptotic cell clearance	1.262141e-8
GO:0051347	positive regulation of transferase activity	1.279908e-8
GO:0048646	anatomical structure formation involved in morphogenesis	1.280187e-8
GO:0035690	cellular response to drug	1.286675e-8
GO:0008366	axon ensheathment	1.379611e-8
GO:0048523	negative regulation of cellular process	1.503258e-8
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.627878e-8
GO:0051179	localization	1.691957e-8
GO:0048729	tissue morphogenesis	1.735469e-8
GO:0032695	negative regulation of interleukin-12 production	1.756736e-8
GO:0043069	negative regulation of programmed cell death	1.777678e-8
GO:0042127	regulation of cell proliferation	1.916360e-8
GO:0045087	innate immune response	1.946441e-8
GO:0060638	mesenchymal-epithelial cell signaling	2.035105e-8
GO:0048878	chemical homeostasis	2.062032e-8
GO:0007243	intracellular protein kinase cascade	2.255034e-8
GO:0032570	response to progesterone stimulus	2.255529e-8
GO:0019725	cellular homeostasis	2.628681e-8
GO:0010763	positive regulation of fibroblast migration	2.657807e-8
GO:0009605	response to external stimulus	2.675715e-8
GO:0031345	negative regulation of cell projection organization	2.682819e-8
GO:0071840	cellular component organization or biogenesis	2.759604e-8
GO:0070271	protein complex biogenesis	2.904315e-8
GO:0048747	muscle fiber development	2.985349e-8
GO:0016043	cellular component organization	3.311612e-8
GO:0034116	positive regulation of heterotypic cell-cell adhesion	3.314596e-8
GO:0051094	positive regulation of developmental process	3.403110e-8
GO:0051247	positive regulation of protein metabolic process	3.508897e-8
GO:0032368	regulation of lipid transport	3.602140e-8
GO:0045073	regulation of chemokine biosynthetic process	3.605109e-8
GO:0043066	negative regulation of apoptosis	3.609745e-8
GO:0042993	positive regulation of transcription factor import into nucleus	3.879796e-8
GO:0070372	regulation of ERK1 and ERK2 cascade	3.958043e-8
GO:0030240	skeletal muscle thin filament assembly	4.127670e-8
GO:0007204	elevation of cytosolic calcium ion concentration	4.181463e-8
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	5.112888e-8
GO:0000819	sister chromatid segregation	5.268442e-8
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5.460407e-8
GO:0000070	mitotic sister chromatid segregation	5.561963e-8
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	5.725480e-8
GO:0033198	response to ATP	6.010070e-8
GO:0031344	regulation of cell projection organization	6.108776e-8
GO:0006461	protein complex assembly	6.519665e-8
GO:0032270	positive regulation of cellular protein metabolic process	8.081839e-8
GO:0044057	regulation of system process	8.931554e-8
GO:0016477	cell migration	8.935778e-8
GO:0033129	positive regulation of histone phosphorylation	9.121734e-8
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	9.286947e-8
GO:0007601	visual perception	1.008439e-7
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	1.026889e-7
GO:0032026	response to magnesium ion	1.044387e-7
GO:0042063	gliogenesis	1.081508e-7
GO:0031401	positive regulation of protein modification process	1.102768e-7
GO:0022008	neurogenesis	1.201391e-7
GO:0032370	positive regulation of lipid transport	1.217063e-7
GO:0048087	positive regulation of developmental pigmentation	1.254205e-7
GO:0090331	negative regulation of platelet aggregation	1.328020e-7
GO:0061110	dense core granule biogenesis	1.328020e-7
GO:0061108	seminal vesicle epithelium development	1.328020e-7
GO:0042628	mating plug formation	1.328020e-7
GO:0050680	negative regulation of epithelial cell proliferation	1.423698e-7
GO:0046825	regulation of protein export from nucleus	1.441940e-7
GO:0050953	sensory perception of light stimulus	1.446806e-7
GO:0001508	regulation of action potential	1.770874e-7
GO:0045664	regulation of neuron differentiation	1.896696e-7
GO:0051282	regulation of sequestering of calcium ion	2.002917e-7
GO:0071345	cellular response to cytokine stimulus	2.089972e-7
GO:0042534	regulation of tumor necrosis factor biosynthetic process	2.253625e-7
GO:2000145	regulation of cell motility	2.267466e-7
GO:0045636	positive regulation of melanocyte differentiation	2.492279e-7
GO:0015791	polyol transport	2.496051e-7
GO:0030194	positive regulation of blood coagulation	2.529126e-7
GO:0051918	negative regulation of fibrinolysis	2.668236e-7
GO:0006468	protein phosphorylation	2.671332e-7
GO:0042108	positive regulation of cytokine biosynthetic process	2.809909e-7
GO:0010631	epithelial cell migration	2.864160e-7
GO:0046688	response to copper ion	2.905433e-7
GO:0070613	regulation of protein processing	2.909223e-7
GO:0014805	smooth muscle adaptation	2.939712e-7
GO:0009582	detection of abiotic stimulus	2.946188e-7
GO:0001934	positive regulation of protein phosphorylation	3.077450e-7
GO:0045124	regulation of bone resorption	3.220138e-7
GO:0070665	positive regulation of leukocyte proliferation	3.284869e-7
GO:0001819	positive regulation of cytokine production	3.314464e-7
GO:0002830	positive regulation of type 2 immune response	3.339081e-7
GO:0042446	hormone biosynthetic process	3.419453e-7
GO:0032757	positive regulation of interleukin-8 production	3.485081e-7
GO:0051649	establishment of localization in cell	3.524418e-7
GO:2000021	regulation of ion homeostasis	3.602971e-7
GO:0006928	cellular component movement	3.648690e-7
GO:0071637	regulation of monocyte chemotactic protein-1 production	3.740127e-7
GO:0072358	cardiovascular system development	3.798019e-7
GO:0042345	regulation of NF-kappaB import into nucleus	3.806848e-7
GO:0043933	macromolecular complex subunit organization	3.902715e-7
GO:0006875	cellular metal ion homeostasis	3.981521e-7
GO:0009617	response to bacterium	4.211281e-7
GO:0010741	negative regulation of intracellular protein kinase cascade	4.242883e-7
GO:0033127	regulation of histone phosphorylation	4.481912e-7
GO:0032675	regulation of interleukin-6 production	4.494917e-7
GO:0030335	positive regulation of cell migration	4.603587e-7
GO:0007267	cell-cell signaling	4.736155e-7
GO:0051234	establishment of localization	4.842024e-7
GO:0080135	regulation of cellular response to stress	4.892898e-7
GO:0006911	phagocytosis, engulfment	4.947028e-7
GO:0040012	regulation of locomotion	5.432208e-7
GO:0032908	regulation of transforming growth factor beta1 production	5.480348e-7
GO:0046627	negative regulation of insulin receptor signaling pathway	5.602620e-7
GO:0035725	sodium ion transmembrane transport	5.817047e-7
GO:0048870	cell motility	5.862484e-7
GO:0014050	negative regulation of glutamate secretion	6.119349e-7
GO:0050778	positive regulation of immune response	6.172856e-7
GO:0048769	sarcomerogenesis	6.174830e-7
GO:0045408	regulation of interleukin-6 biosynthetic process	6.247198e-7
GO:2000147	positive regulation of cell motility	6.612759e-7
GO:0048732	gland development	6.800868e-7
GO:0090310	negative regulation of methylation-dependent chromatin silencing	6.859609e-7
GO:0030728	ovulation	7.103206e-7
GO:0030593	neutrophil chemotaxis	7.379829e-7
GO:0051705	behavioral interaction between organisms	7.733021e-7
GO:0007399	nervous system development	7.789386e-7
GO:0043500	muscle adaptation	7.883850e-7
GO:0051917	regulation of fibrinolysis	7.992996e-7
GO:0051049	regulation of transport	8.220654e-7
GO:0051092	positive regulation of NF-kappaB transcription factor activity	8.593260e-7
GO:0045596	negative regulation of cell differentiation	9.071608e-7
GO:0007566	embryo implantation	9.156535e-7
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	9.339547e-7
GO:0032879	regulation of localization	9.384390e-7
GO:0050870	positive regulation of T cell activation	9.813055e-7
GO:2001020	regulation of response to DNA damage stimulus	9.843034e-7
GO:0055065	metal ion homeostasis	9.883139e-7
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.011421e-6
GO:0033280	response to vitamin D	1.013083e-6
GO:0006796	phosphate-containing compound metabolic process	1.047013e-6
GO:0008219	cell death	1.054639e-6
GO:0007420	brain development	1.065670e-6
GO:0046850	regulation of bone remodeling	1.111888e-6
GO:0033059	cellular pigmentation	1.130888e-6
GO:0034097	response to cytokine stimulus	1.165695e-6
GO:0010466	negative regulation of peptidase activity	1.220025e-6
GO:0030730	sequestering of triglyceride	1.226147e-6
GO:0016265	death	1.255338e-6
GO:0051046	regulation of secretion	1.281235e-6
GO:0009314	response to radiation	1.340402e-6
GO:0071346	cellular response to interferon-gamma	1.360580e-6
GO:0016310	phosphorylation	1.469512e-6
GO:0060558	regulation of calcidiol 1-monooxygenase activity	1.471349e-6
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.485028e-6
GO:0045861	negative regulation of proteolysis	1.549623e-6
GO:0003007	heart morphogenesis	1.590665e-6
GO:0040017	positive regulation of locomotion	1.602079e-6
GO:0030003	cellular cation homeostasis	1.663253e-6
GO:0051893	regulation of focal adhesion assembly	1.666202e-6
GO:0051209	release of sequestered calcium ion into cytosol	1.683631e-6
GO:0044060	regulation of endocrine process	1.691297e-6
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	1.694521e-6
GO:0032874	positive regulation of stress-activated MAPK cascade	1.732764e-6
GO:0015793	glycerol transport	1.769147e-6
GO:0045634	regulation of melanocyte differentiation	1.777945e-6
GO:0050820	positive regulation of coagulation	1.827758e-6
GO:0050678	regulation of epithelial cell proliferation	1.893913e-6
GO:0007179	transforming growth factor beta receptor signaling pathway	2.024888e-6
GO:0071310	cellular response to organic substance	2.028193e-6
GO:0048608	reproductive structure development	2.067908e-6
GO:0000087	M phase of mitotic cell cycle	2.068013e-6
GO:0010575	positive regulation vascular endothelial growth factor production	2.131219e-6
GO:0052572	response to host immune response	2.133892e-6
GO:0034405	response to fluid shear stress	2.154343e-6
GO:0051270	regulation of cellular component movement	2.165285e-6
GO:0007568	aging	2.197715e-6
GO:0001659	temperature homeostasis	2.203446e-6
GO:0010975	regulation of neuron projection development	2.232610e-6
GO:0007507	heart development	2.460495e-6
GO:0055001	muscle cell development	2.466382e-6
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	2.479991e-6
GO:0032891	negative regulation of organic acid transport	2.618132e-6
GO:0051272	positive regulation of cellular component movement	2.857831e-6
GO:0042592	homeostatic process	2.929388e-6
GO:0070374	positive regulation of ERK1 and ERK2 cascade	3.019452e-6
GO:0030001	metal ion transport	3.099054e-6
GO:0043535	regulation of blood vessel endothelial cell migration	3.145246e-6
GO:0060429	epithelium development	3.191099e-6
GO:0030334	regulation of cell migration	3.210902e-6
GO:0000279	M phase	3.300380e-6
GO:0035066	positive regulation of histone acetylation	3.359496e-6
GO:0055003	cardiac myofibril assembly	3.415756e-6
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	3.451857e-6
GO:0007050	cell cycle arrest	3.739173e-6
GO:0002237	response to molecule of bacterial origin	3.815647e-6
GO:0015672	monovalent inorganic cation transport	3.825339e-6
GO:0043408	regulation of MAPKKK cascade	3.869768e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.045872e-6
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	4.049185e-6
GO:0043086	negative regulation of catalytic activity	4.067649e-6
GO:0002439	chronic inflammatory response to antigenic stimulus	4.071641e-6
GO:0042307	positive regulation of protein import into nucleus	4.079642e-6
GO:0035176	social behavior	4.351801e-6
GO:0032989	cellular component morphogenesis	4.581097e-6
GO:0051450	myoblast proliferation	4.581499e-6
GO:0006633	fatty acid biosynthetic process	4.698347e-6
GO:0008016	regulation of heart contraction	4.763854e-6
GO:0043085	positive regulation of catalytic activity	4.883501e-6
GO:0007049	cell cycle	4.900295e-6
GO:0055080	cation homeostasis	4.952388e-6
GO:0051054	positive regulation of DNA metabolic process	5.217256e-6
GO:0006810	transport	5.233384e-6
GO:0009987	cellular process	5.527649e-6
GO:0012501	programmed cell death	5.553794e-6
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	5.560926e-6
GO:0030239	myofibril assembly	5.616062e-6
GO:0090308	regulation of methylation-dependent chromatin silencing	5.672957e-6
GO:0042391	regulation of membrane potential	5.743457e-6
GO:0001706	endoderm formation	5.993525e-6
GO:0051249	regulation of lymphocyte activation	6.046350e-6
GO:0051047	positive regulation of secretion	6.124293e-6
GO:0071901	negative regulation of protein serine/threonine kinase activity	6.208233e-6
GO:0014706	striated muscle tissue development	6.271850e-6
GO:0051251	positive regulation of lymphocyte activation	6.380611e-6
GO:0035270	endocrine system development	6.397220e-6
GO:0050906	detection of stimulus involved in sensory perception	6.542938e-6
GO:0007067	mitosis	6.750543e-6
GO:0043536	positive regulation of blood vessel endothelial cell migration	6.775309e-6
GO:0006812	cation transport	6.867634e-6
GO:0051241	negative regulation of multicellular organismal process	6.980293e-6
GO:0050863	regulation of T cell activation	7.435082e-6
GO:0048699	generation of neurons	7.439045e-6
GO:0060411	cardiac septum morphogenesis	7.535400e-6
GO:0022407	regulation of cell-cell adhesion	7.589579e-6
GO:0002683	negative regulation of immune system process	7.700492e-6
GO:0031622	positive regulation of fever generation	7.706180e-6
GO:0045616	regulation of keratinocyte differentiation	8.095940e-6
GO:0048070	regulation of developmental pigmentation	8.142872e-6
GO:0060754	positive regulation of mast cell chemotaxis	8.169133e-6
GO:0008354	germ cell migration	8.216811e-6
GO:0003006	developmental process involved in reproduction	8.252888e-6
GO:0090130	tissue migration	8.329860e-6
GO:0034114	regulation of heterotypic cell-cell adhesion	8.329860e-6
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	8.329860e-6
GO:0035162	embryonic hemopoiesis	8.373611e-6
GO:0070668	positive regulation of mast cell proliferation	8.373859e-6
GO:0010001	glial cell differentiation	8.611123e-6
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	8.635724e-6
GO:0010829	negative regulation of glucose transport	8.692041e-6
GO:0019226	transmission of nerve impulse	8.714475e-6
GO:0048670	regulation of collateral sprouting	8.721949e-6
GO:0051960	regulation of nervous system development	8.844449e-6
GO:0065003	macromolecular complex assembly	8.901035e-6
GO:0021782	glial cell development	8.972158e-6
GO:0034764	positive regulation of transmembrane transport	9.197836e-6
GO:0010941	regulation of cell death	9.450665e-6
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	9.455432e-6
GO:0007565	female pregnancy	9.633628e-6
GO:0043407	negative regulation of MAP kinase activity	9.970918e-6
GO:0043067	regulation of programmed cell death	1.021585e-5
GO:0048285	organelle fission	1.044385e-5
GO:0002906	negative regulation of mature B cell apoptosis	1.061048e-5
GO:0046883	regulation of hormone secretion	1.064110e-5
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	1.077430e-5
GO:0031652	positive regulation of heat generation	1.146766e-5
GO:0032648	regulation of interferon-beta production	1.156394e-5
GO:0032496	response to lipopolysaccharide	1.158806e-5
GO:0034110	regulation of homotypic cell-cell adhesion	1.171727e-5
GO:0000959	mitochondrial RNA metabolic process	1.191699e-5
GO:0010927	cellular component assembly involved in morphogenesis	1.194020e-5
GO:0043163	cell envelope organization	1.208567e-5
GO:0055002	striated muscle cell development	1.218724e-5
GO:0051384	response to glucocorticoid stimulus	1.228798e-5
GO:0033157	regulation of intracellular protein transport	1.242834e-5
GO:0060174	limb bud formation	1.276289e-5
GO:0042663	regulation of endodermal cell fate specification	1.305947e-5
GO:0060478	acrosomal vesicle exocytosis	1.316218e-5
GO:0051223	regulation of protein transport	1.364933e-5
GO:0002579	positive regulation of antigen processing and presentation	1.431885e-5
GO:0042493	response to drug	1.456825e-5
GO:0019827	stem cell maintenance	1.462918e-5
GO:0009887	organ morphogenesis	1.509371e-5
GO:0007600	sensory perception	1.535307e-5
GO:0060907	positive regulation of macrophage cytokine production	1.566355e-5

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	1.649570e-25
GO:0006950	response to stress	3.856190e-25
GO:0002376	immune system process	1.163702e-23
GO:0009611	response to wounding	1.700537e-18
GO:0032501	multicellular organismal process	3.707699e-18
GO:0006955	immune response	2.580596e-17
GO:0042221	response to chemical stimulus	4.009167e-17
GO:0042060	wound healing	3.218106e-16
GO:0048513	organ development	1.621226e-15
GO:0042127	regulation of cell proliferation	7.098674e-15
GO:0002252	immune effector process	9.453453e-15
GO:0051247	positive regulation of protein metabolic process	1.012347e-14
GO:0001775	cell activation	2.244677e-14
GO:0010033	response to organic substance	8.503933e-14
GO:0009605	response to external stimulus	8.737202e-14
GO:0006952	defense response	2.662359e-13
GO:0051716	cellular response to stimulus	3.940026e-13
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	5.869391e-13
GO:0048731	system development	1.005607e-12
GO:0009308	amine metabolic process	1.686989e-12
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	2.762929e-12
GO:0032270	positive regulation of cellular protein metabolic process	3.374929e-12
GO:0032940	secretion by cell	4.754038e-12
GO:0051179	localization	5.858280e-12
GO:0002684	positive regulation of immune system process	6.583226e-12
GO:0023056	positive regulation of signaling	7.343721e-12
GO:0048856	anatomical structure development	9.600323e-12
GO:0032879	regulation of localization	1.000576e-11
GO:0007599	hemostasis	1.590836e-11
GO:0065008	regulation of biological quality	1.769839e-11
GO:0008285	negative regulation of cell proliferation	1.828811e-11
GO:0042327	positive regulation of phosphorylation	1.976244e-11
GO:0009887	organ morphogenesis	2.204306e-11
GO:0010647	positive regulation of cell communication	2.313555e-11
GO:0008284	positive regulation of cell proliferation	2.761603e-11
GO:0051049	regulation of transport	2.946053e-11
GO:0009967	positive regulation of signal transduction	3.008167e-11
GO:0007154	cell communication	3.385000e-11
GO:0006810	transport	4.364745e-11
GO:0051246	regulation of protein metabolic process	5.008691e-11
GO:0051234	establishment of localization	5.124151e-11
GO:0031401	positive regulation of protein modification process	5.175000e-11
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	5.268016e-11
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	5.327082e-11
GO:0030162	regulation of proteolysis	5.650555e-11
GO:0045321	leukocyte activation	5.723034e-11
GO:0045937	positive regulation of phosphate metabolic process	6.844942e-11
GO:0050678	regulation of epithelial cell proliferation	7.488096e-11
GO:0048518	positive regulation of biological process	1.182144e-10
GO:0048522	positive regulation of cellular process	1.293320e-10
GO:0048584	positive regulation of response to stimulus	1.352182e-10
GO:0009612	response to mechanical stimulus	1.567842e-10
GO:0009914	hormone transport	1.633116e-10
GO:0007596	blood coagulation	1.633116e-10
GO:0003008	system process	1.685959e-10
GO:0051649	establishment of localization in cell	1.812948e-10
GO:0032502	developmental process	2.994191e-10
GO:0001934	positive regulation of protein phosphorylation	3.311453e-10
GO:0051704	multi-organism process	3.817671e-10
GO:0007275	multicellular organismal development	4.311188e-10
GO:0002443	leukocyte mediated immunity	7.029356e-10
GO:0023052	signaling	7.323078e-10
GO:0050776	regulation of immune response	7.856063e-10
GO:0001932	regulation of protein phosphorylation	1.470952e-9
GO:0050778	positive regulation of immune response	1.870514e-9
GO:0046427	positive regulation of JAK-STAT cascade	2.083123e-9
GO:0044106	cellular amine metabolic process	2.271468e-9
GO:0010604	positive regulation of macromolecule metabolic process	2.458243e-9
GO:0031399	regulation of protein modification process	2.581284e-9
GO:0070887	cellular response to chemical stimulus	3.870972e-9
GO:0042129	regulation of T cell proliferation	4.282408e-9
GO:0021543	pallium development	4.421062e-9
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	4.669017e-9
GO:0007507	heart development	5.703948e-9
GO:0010740	positive regulation of intracellular protein kinase cascade	6.182797e-9
GO:0009719	response to endogenous stimulus	6.241239e-9
GO:0019370	leukotriene biosynthetic process	6.615830e-9
GO:0009790	embryo development	6.692843e-9
GO:0048568	embryonic organ development	7.726769e-9
GO:0015837	amine transport	7.960799e-9
GO:0009888	tissue development	8.031069e-9
GO:0035886	vascular smooth muscle cell differentiation	8.309150e-9
GO:0046903	secretion	8.681127e-9
GO:0042102	positive regulation of T cell proliferation	9.258491e-9
GO:0050870	positive regulation of T cell activation	9.383090e-9
GO:0065007	biological regulation	1.149450e-8
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	1.400953e-8
GO:0019220	regulation of phosphate metabolic process	1.735071e-8
GO:0006959	humoral immune response	2.371842e-8
GO:0012502	induction of programmed cell death	2.403150e-8
GO:0046631	alpha-beta T cell activation	2.659418e-8
GO:0051641	cellular localization	2.684927e-8
GO:0031032	actomyosin structure organization	2.790252e-8
GO:0050670	regulation of lymphocyte proliferation	2.816090e-8
GO:0006691	leukotriene metabolic process	2.868442e-8
GO:0009893	positive regulation of metabolic process	2.996494e-8
GO:0070663	regulation of leukocyte proliferation	3.093582e-8
GO:0032944	regulation of mononuclear cell proliferation	3.171233e-8
GO:0006917	induction of apoptosis	3.360289e-8
GO:0060341	regulation of cellular localization	3.618157e-8
GO:0030212	hyaluronan metabolic process	3.889382e-8
GO:0002696	positive regulation of leukocyte activation	4.946586e-8
GO:0002449	lymphocyte mediated immunity	4.972883e-8
GO:0007586	digestion	5.118455e-8
GO:0045058	T cell selection	5.354586e-8
GO:0014904	myotube cell development	5.776783e-8
GO:0014732	skeletal muscle atrophy	5.987126e-8
GO:0055006	cardiac cell development	6.444993e-8
GO:0051050	positive regulation of transport	6.686335e-8
GO:0008593	regulation of Notch signaling pathway	6.823346e-8
GO:0009725	response to hormone stimulus	7.213509e-8
GO:0042325	regulation of phosphorylation	8.357556e-8
GO:0032268	regulation of cellular protein metabolic process	8.556014e-8
GO:0007165	signal transduction	9.477975e-8
GO:0031325	positive regulation of cellular metabolic process	9.767455e-8
GO:0030104	water homeostasis	9.874873e-8
GO:0008610	lipid biosynthetic process	1.012634e-7
GO:0023061	signal release	1.044042e-7
GO:0019538	protein metabolic process	1.054880e-7
GO:0031667	response to nutrient levels	1.068247e-7
GO:0030855	epithelial cell differentiation	1.111033e-7
GO:0052547	regulation of peptidase activity	1.169311e-7
GO:0021537	telencephalon development	1.422980e-7
GO:0051145	smooth muscle cell differentiation	1.455840e-7
GO:0002694	regulation of leukocyte activation	1.495007e-7
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	1.506979e-7
GO:0010035	response to inorganic substance	1.517679e-7
GO:0033005	positive regulation of mast cell activation	1.589097e-7
GO:0051606	detection of stimulus	1.590432e-7
GO:0046879	hormone secretion	1.607330e-7
GO:0009991	response to extracellular stimulus	1.685946e-7
GO:0007600	sensory perception	1.981324e-7
GO:0050671	positive regulation of lymphocyte proliferation	2.009849e-7
GO:0051186	cofactor metabolic process	2.036238e-7
GO:0042180	cellular ketone metabolic process	2.064456e-7
GO:0000003	reproduction	2.085250e-7
GO:0030239	myofibril assembly	2.246569e-7
GO:0050867	positive regulation of cell activation	2.305081e-7
GO:0032946	positive regulation of mononuclear cell proliferation	2.305846e-7
GO:0046649	lymphocyte activation	2.306913e-7
GO:0010627	regulation of intracellular protein kinase cascade	2.517979e-7
GO:0046425	regulation of JAK-STAT cascade	2.552638e-7
GO:0055114	oxidation-reduction process	2.730215e-7
GO:0019752	carboxylic acid metabolic process	2.877864e-7
GO:0048534	hemopoietic or lymphoid organ development	2.905921e-7
GO:0002521	leukocyte differentiation	2.968395e-7
GO:0001654	eye development	2.971386e-7
GO:0048583	regulation of response to stimulus	3.091635e-7
GO:0006732	coenzyme metabolic process	3.404905e-7
GO:0070665	positive regulation of leukocyte proliferation	3.445040e-7
GO:0006520	cellular amino acid metabolic process	3.660436e-7
GO:0070848	response to growth factor stimulus	3.703259e-7
GO:0043306	positive regulation of mast cell degranulation	3.950441e-7
GO:0021761	limbic system development	3.980093e-7
GO:0009896	positive regulation of catabolic process	4.000623e-7
GO:0034498	early endosome to Golgi transport	4.218746e-7
GO:0002544	chronic inflammatory response	4.299479e-7
GO:0003012	muscle system process	4.338778e-7
GO:0048878	chemical homeostasis	4.375862e-7
GO:0060795	cell fate commitment involved in formation of primary germ layers	4.458794e-7
GO:0006790	sulfur compound metabolic process	4.461297e-7
GO:0042493	response to drug	5.154081e-7
GO:0002275	myeloid cell activation involved in immune response	5.711912e-7
GO:0001835	blastocyst hatching	5.999126e-7
GO:0045747	positive regulation of Notch signaling pathway	6.173841e-7
GO:0002520	immune system development	6.378566e-7
GO:0002439	chronic inflammatory response to antigenic stimulus	6.440462e-7
GO:0051043	regulation of membrane protein ectodomain proteolysis	6.577539e-7
GO:0050878	regulation of body fluid levels	6.587439e-7
GO:0046324	regulation of glucose import	6.707430e-7
GO:0055001	muscle cell development	6.880500e-7
GO:0051533	positive regulation of NFAT protein import into nucleus	7.245188e-7
GO:0008544	epidermis development	7.693914e-7
GO:0042035	regulation of cytokine biosynthetic process	8.269369e-7
GO:0043434	response to peptide hormone stimulus	8.416061e-7
GO:0008283	cell proliferation	9.625335e-7
GO:0022414	reproductive process	9.679477e-7
GO:0006629	lipid metabolic process	9.792001e-7
GO:0060548	negative regulation of cell death	9.837530e-7
GO:0003007	heart morphogenesis	9.973773e-7
GO:0006082	organic acid metabolic process	1.031327e-6
GO:0043954	cellular component maintenance	1.112751e-6
GO:0030003	cellular cation homeostasis	1.138945e-6
GO:0044283	small molecule biosynthetic process	1.210050e-6
GO:0043009	chordate embryonic development	1.239645e-6
GO:0042110	T cell activation	1.339690e-6
GO:0071705	nitrogen compound transport	1.510279e-6
GO:0043302	positive regulation of leukocyte degranulation	1.517614e-6
GO:0002253	activation of immune response	1.564674e-6
GO:0002456	T cell mediated immunity	1.576680e-6
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.590174e-6
GO:0071702	organic substance transport	1.702325e-6
GO:0042692	muscle cell differentiation	1.756572e-6
GO:0010941	regulation of cell death	1.779109e-6
GO:0010466	negative regulation of peptidase activity	1.830807e-6
GO:0043901	negative regulation of multi-organism process	1.846491e-6
GO:0065009	regulation of molecular function	1.853722e-6
GO:0045047	protein targeting to ER	1.856091e-6
GO:0021766	hippocampus development	1.881960e-6
GO:0050863	regulation of T cell activation	1.898797e-6
GO:0009792	embryo development ending in birth or egg hatching	1.939750e-6
GO:0043069	negative regulation of programmed cell death	1.957677e-6
GO:0009628	response to abiotic stimulus	1.958534e-6
GO:0030154	cell differentiation	1.961716e-6
GO:0044281	small molecule metabolic process	2.061628e-6
GO:0048519	negative regulation of biological process	2.122406e-6
GO:0023051	regulation of signaling	2.125158e-6
GO:0030097	hemopoiesis	2.127637e-6
GO:0051187	cofactor catabolic process	2.159401e-6
GO:0055013	cardiac muscle cell development	2.168847e-6
GO:0002682	regulation of immune system process	2.214852e-6
GO:0046633	alpha-beta T cell proliferation	2.251346e-6
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	2.315718e-6
GO:0007423	sensory organ development	2.318799e-6
GO:0002366	leukocyte activation involved in immune response	2.354703e-6
GO:0009966	regulation of signal transduction	2.377887e-6
GO:0045821	positive regulation of glycolysis	2.541417e-6
GO:0006954	inflammatory response	2.573924e-6
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.713333e-6
GO:0043900	regulation of multi-organism process	2.837457e-6
GO:0014888	striated muscle adaptation	2.905143e-6
GO:0043067	regulation of programmed cell death	2.999516e-6
GO:0010837	regulation of keratinocyte proliferation	3.023127e-6
GO:0052548	regulation of endopeptidase activity	3.092559e-6
GO:0009653	anatomical structure morphogenesis	3.157873e-6
GO:0050865	regulation of cell activation	3.239090e-6
GO:0060741	prostate gland stromal morphogenesis	3.253075e-6
GO:0043366	beta selection	3.261360e-6
GO:0043066	negative regulation of apoptosis	3.322552e-6
GO:0055082	cellular chemical homeostasis	3.420687e-6
GO:0046942	carboxylic acid transport	3.457018e-6
GO:0051093	negative regulation of developmental process	3.505265e-6
GO:0043501	skeletal muscle adaptation	3.513179e-6
GO:0050790	regulation of catalytic activity	3.638547e-6
GO:0051251	positive regulation of lymphocyte activation	3.690023e-6
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	3.843023e-6
GO:0042473	outer ear morphogenesis	3.862899e-6
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3.933035e-6
GO:0055080	cation homeostasis	3.940589e-6
GO:0007501	mesodermal cell fate specification	4.031893e-6
GO:0060850	regulation of transcription involved in cell fate commitment	4.125970e-6
GO:0002250	adaptive immune response	4.134961e-6
GO:0051239	regulation of multicellular organismal process	4.174007e-6
GO:0001666	response to hypoxia	4.281803e-6
GO:0034097	response to cytokine stimulus	4.321892e-6
GO:0045787	positive regulation of cell cycle	4.344467e-6
GO:0035556	intracellular signal transduction	4.408324e-6
GO:0002757	immune response-activating signal transduction	4.602640e-6
GO:0034392	negative regulation of smooth muscle cell apoptosis	4.621853e-6
GO:0042981	regulation of apoptosis	4.700546e-6
GO:0043304	regulation of mast cell degranulation	4.713974e-6
GO:0045184	establishment of protein localization	4.757689e-6
GO:0045062	extrathymic T cell selection	4.782193e-6
GO:0080134	regulation of response to stress	4.819737e-6
GO:0035630	bone mineralization involved in bone maturation	4.891086e-6
GO:0072594	establishment of protein localization to organelle	5.040111e-6
GO:0046640	regulation of alpha-beta T cell proliferation	5.299590e-6
GO:0000041	transition metal ion transport	5.369096e-6
GO:0050877	neurological system process	5.397677e-6
GO:0009891	positive regulation of biosynthetic process	5.443518e-6
GO:0015031	protein transport	5.581910e-6
GO:0031328	positive regulation of cellular biosynthetic process	5.825632e-6
GO:0034391	regulation of smooth muscle cell apoptosis	6.095036e-6
GO:0033006	regulation of mast cell activation involved in immune response	6.142626e-6
GO:0050654	chondroitin sulfate proteoglycan metabolic process	6.323090e-6
GO:0050789	regulation of biological process	6.476992e-6
GO:0050432	catecholamine secretion	6.694224e-6
GO:0048545	response to steroid hormone stimulus	6.730120e-6
GO:0002429	immune response-activating cell surface receptor signaling pathway	6.942437e-6
GO:0030900	forebrain development	7.158401e-6
GO:0033762	response to glucagon stimulus	7.290982e-6
GO:0045165	cell fate commitment	7.306658e-6
GO:0001714	endodermal cell fate specification	7.587354e-6
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	8.173687e-6
GO:0006029	proteoglycan metabolic process	8.343638e-6
GO:0051046	regulation of secretion	8.380907e-6
GO:0042108	positive regulation of cytokine biosynthetic process	8.463795e-6
GO:0010646	regulation of cell communication	8.543300e-6
GO:0007492	endoderm development	8.797336e-6
GO:0031000	response to caffeine	8.990553e-6
GO:0045840	positive regulation of mitosis	9.259994e-6
GO:0042668	auditory receptor cell fate determination	9.857844e-6
GO:0048869	cellular developmental process	1.009114e-5
GO:0010557	positive regulation of macromolecule biosynthetic process	1.014824e-5
GO:0006084	acetyl-CoA metabolic process	1.023728e-5
GO:0032819	positive regulation of natural killer cell proliferation	1.036471e-5
GO:0018149	peptide cross-linking	1.043271e-5
GO:0001709	cell fate determination	1.056148e-5
GO:2000026	regulation of multicellular organismal development	1.060169e-5
GO:0010827	regulation of glucose transport	1.060453e-5
GO:0045471	response to ethanol	1.124479e-5
GO:0051707	response to other organism	1.126973e-5
GO:0071310	cellular response to organic substance	1.152698e-5
GO:0046456	icosanoid biosynthetic process	1.153004e-5
GO:0042176	regulation of protein catabolic process	1.163283e-5
GO:0032844	regulation of homeostatic process	1.181800e-5
GO:0044130	negative regulation of growth of symbiont in host	1.187773e-5
GO:0072358	cardiovascular system development	1.189542e-5
GO:0009913	epidermal cell differentiation	1.205141e-5
GO:0045494	photoreceptor cell maintenance	1.212718e-5
GO:0015849	organic acid transport	1.235486e-5
GO:0070977	bone maturation	1.249346e-5
GO:0035051	cardiac cell differentiation	1.267526e-5
GO:0051648	vesicle localization	1.288315e-5
GO:0006812	cation transport	1.316116e-5
GO:0033036	macromolecule localization	1.317424e-5
GO:0060037	pharyngeal system development	1.318015e-5
GO:0002577	regulation of antigen processing and presentation	1.342881e-5
GO:0048242	epinephrine secretion	1.387964e-5
GO:0043010	camera-type eye development	1.410362e-5
GO:0048562	embryonic organ morphogenesis	1.418908e-5
GO:0009109	coenzyme catabolic process	1.436991e-5
GO:0007006	mitochondrial membrane organization	1.451572e-5
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.461642e-5
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.461642e-5
GO:0045214	sarcomere organization	1.461896e-5
GO:0002819	regulation of adaptive immune response	1.492908e-5
GO:0006875	cellular metal ion homeostasis	1.509465e-5
GO:0006873	cellular ion homeostasis	1.513673e-5
GO:0043408	regulation of MAPKKK cascade	1.529354e-5
GO:0045338	farnesyl diphosphate metabolic process	1.599771e-5
GO:0009581	detection of external stimulus	1.627001e-5
GO:0015876	acetyl-CoA transport	1.639823e-5
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.639823e-5
GO:0051249	regulation of lymphocyte activation	1.673431e-5
GO:0055065	metal ion homeostasis	1.697662e-5
GO:0070727	cellular macromolecule localization	1.703245e-5
GO:0055085	transmembrane transport	1.708955e-5
GO:0043368	positive T cell selection	1.710830e-5
GO:0032854	positive regulation of Rap GTPase activity	1.723515e-5
GO:0046326	positive regulation of glucose import	1.748588e-5
GO:0007584	response to nutrient	1.762477e-5
GO:0001892	embryonic placenta development	1.794164e-5
GO:0032878	regulation of establishment or maintenance of cell polarity	1.805163e-5
GO:0031214	biomineral tissue development	1.890085e-5
GO:0001890	placenta development	1.890305e-5
GO:0014889	muscle atrophy	1.908553e-5
GO:0034613	cellular protein localization	1.960238e-5
GO:0010838	positive regulation of keratinocyte proliferation	2.012110e-5
GO:0001711	endodermal cell fate commitment	2.013456e-5
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	2.055623e-5
GO:0035295	tube development	2.066542e-5
GO:0070972	protein localization in endoplasmic reticulum	2.070382e-5
GO:0050853	B cell receptor signaling pathway	2.112520e-5
GO:0007605	sensory perception of sound	2.123985e-5
GO:0050793	regulation of developmental process	2.130137e-5
GO:0051094	positive regulation of developmental process	2.130635e-5
GO:0046632	alpha-beta T cell differentiation	2.179360e-5
GO:0010660	regulation of muscle cell apoptosis	2.234716e-5
GO:0090199	regulation of release of cytochrome c from mitochondria	2.305246e-5
GO:0048592	eye morphogenesis	2.307734e-5
GO:0061198	fungiform papilla formation	2.312424e-5
GO:0001866	NK T cell proliferation	2.325653e-5
GO:0031347	regulation of defense response	2.342426e-5
GO:0071902	positive regulation of protein serine/threonine kinase activity	2.349870e-5
GO:0008104	protein localization	2.459478e-5
GO:0050801	ion homeostasis	2.545897e-5
GO:0009636	response to toxin	2.547367e-5
GO:0050851	antigen receptor-mediated signaling pathway	2.568705e-5
GO:2000021	regulation of ion homeostasis	2.571594e-5
GO:0050954	sensory perception of mechanical stimulus	2.696649e-5
GO:0045786	negative regulation of cell cycle	2.698299e-5
GO:0006022	aminoglycan metabolic process	2.727518e-5
GO:0002768	immune response-regulating cell surface receptor signaling pathway	2.749374e-5
GO:0048729	tissue morphogenesis	2.777198e-5
GO:0006427	histidyl-tRNA aminoacylation	2.802903e-5
GO:0002674	negative regulation of acute inflammatory response	2.910749e-5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	2.984898e-5
GO:0051924	regulation of calcium ion transport	2.992423e-5
GO:0045621	positive regulation of lymphocyte differentiation	3.063701e-5
GO:0002764	immune response-regulating signaling pathway	3.081157e-5
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	3.126239e-5
GO:0010832	negative regulation of myotube differentiation	3.126239e-5
GO:0007155	cell adhesion	3.201410e-5
GO:0007166	cell surface receptor linked signaling pathway	3.221712e-5
GO:0046356	acetyl-CoA catabolic process	3.265163e-5
GO:0033137	negative regulation of peptidyl-serine phosphorylation	3.287871e-5
GO:0061196	fungiform papilla development	3.290379e-5
GO:0006636	unsaturated fatty acid biosynthetic process	3.431057e-5
GO:0030001	metal ion transport	3.439584e-5
GO:0051705	behavioral interaction between organisms	3.448956e-5
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	3.502473e-5
GO:0045087	innate immune response	3.531629e-5
GO:0097084	vascular smooth muscle cell development	3.532635e-5
GO:0009791	post-embryonic development	3.618391e-5
GO:0007417	central nervous system development	3.674242e-5
GO:0048523	negative regulation of cellular process	3.726613e-5
GO:0001704	formation of primary germ layer	3.733871e-5
GO:0044092	negative regulation of molecular function	3.887843e-5
GO:0043588	skin development	3.988150e-5
GO:0045861	negative regulation of proteolysis	4.091624e-5
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	4.163490e-5
GO:0010656	negative regulation of muscle cell apoptosis	4.186758e-5
GO:0010817	regulation of hormone levels	4.423941e-5
GO:0040007	growth	4.590034e-5
GO:0009064	glutamine family amino acid metabolic process	4.593901e-5
GO:0046684	response to pyrethroid	4.623535e-5
GO:0051030	snRNA transport	4.634645e-5
GO:0043299	leukocyte degranulation	4.700737e-5
GO:0010735	positive regulation of transcription via serum response element binding	4.773135e-5
GO:0015819	lysine transport	4.854190e-5
GO:0015822	ornithine transport	4.854190e-5
GO:0009098	leucine biosynthetic process	4.854190e-5
GO:0006550	isoleucine catabolic process	4.854190e-5
GO:0060347	heart trabecula formation	4.889090e-5
GO:0022610	biological adhesion	4.919421e-5
GO:0051240	positive regulation of multicellular organismal process	4.945422e-5
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	4.948460e-5
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	4.963870e-5
GO:0050680	negative regulation of epithelial cell proliferation	4.976809e-5
GO:0014896	muscle hypertrophy	5.000355e-5
GO:0045732	positive regulation of protein catabolic process	5.081048e-5
GO:0007608	sensory perception of smell	5.162219e-5
GO:0001701	in utero embryonic development	5.185710e-5
GO:0015938	coenzyme A catabolic process	5.223115e-5
GO:0008616	queuosine biosynthetic process	5.223115e-5
GO:0055003	cardiac myofibril assembly	5.307997e-5
GO:0048597	post-embryonic camera-type eye morphogenesis	5.356188e-5
GO:0045597	positive regulation of cell differentiation	5.409945e-5
GO:0043269	regulation of ion transport	5.419201e-5
GO:0071900	regulation of protein serine/threonine kinase activity	5.447704e-5
GO:2000980	regulation of inner ear receptor cell differentiation	5.495794e-5
GO:0001887	selenium compound metabolic process	5.528952e-5
GO:0002697	regulation of immune effector process	5.549811e-5
GO:0048563	post-embryonic organ morphogenesis	5.583867e-5
GO:0043931	ossification involved in bone maturation	5.614697e-5
GO:0043500	muscle adaptation	5.655498e-5
GO:0009309	amine biosynthetic process	5.669772e-5
GO:0009607	response to biotic stimulus	5.705376e-5
GO:0014075	response to amine stimulus	5.747153e-5
GO:0042471	ear morphogenesis	5.828204e-5
GO:0003205	cardiac chamber development	5.935662e-5
GO:0045055	regulated secretory pathway	6.109872e-5
GO:0048050	post-embryonic eye morphogenesis	6.391022e-5
GO:0033364	mast cell secretory granule organization	6.482013e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	6.583958e-5
GO:0045994	positive regulation of translational initiation by iron	6.583958e-5
GO:0002037	negative regulation of L-glutamate transport	6.583958e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	6.583958e-5
GO:0001821	histamine secretion	6.647907e-5
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	6.691244e-5
GO:0060788	ectodermal placode formation	6.757781e-5
GO:0001708	cell fate specification	6.762093e-5
GO:0006695	cholesterol biosynthetic process	6.817622e-5
GO:0010522	regulation of calcium ion transport into cytosol	6.878850e-5
GO:0009886	post-embryonic morphogenesis	6.898276e-5
GO:0002821	positive regulation of adaptive immune response	6.979797e-5
GO:0010828	positive regulation of glucose transport	7.435851e-5
GO:0001817	regulation of cytokine production	7.492973e-5
GO:0060947	cardiac vascular smooth muscle cell differentiation	7.602590e-5
GO:0043065	positive regulation of apoptosis	7.643865e-5
GO:0055007	cardiac muscle cell differentiation	7.669006e-5
GO:0051726	regulation of cell cycle	7.669583e-5
GO:0043406	positive regulation of MAP kinase activity	7.673692e-5
GO:0030029	actin filament-based process	7.707498e-5
GO:0007601	visual perception	7.816540e-5
GO:0045073	regulation of chemokine biosynthetic process	7.892798e-5
GO:0021987	cerebral cortex development	7.941303e-5
GO:0042592	homeostatic process	7.974298e-5
GO:0030098	lymphocyte differentiation	8.097477e-5
GO:0070482	response to oxygen levels	8.111909e-5
GO:0050794	regulation of cellular process	8.247777e-5
GO:0044272	sulfur compound biosynthetic process	8.449790e-5
GO:0030203	glycosaminoglycan metabolic process	8.544259e-5
GO:0048660	regulation of smooth muscle cell proliferation	8.697011e-5
GO:0035987	endodermal cell differentiation	8.903367e-5
GO:0010927	cellular component assembly involved in morphogenesis	8.918994e-5
GO:0030217	T cell differentiation	9.151768e-5
GO:0015711	organic anion transport	9.274241e-5
GO:0015844	monoamine transport	9.311517e-5
GO:0042474	middle ear morphogenesis	9.311517e-5
GO:0010038	response to metal ion	9.326530e-5
GO:0050973	detection of mechanical stimulus involved in equilibrioception	9.337884e-5
GO:0043068	positive regulation of programmed cell death	9.383637e-5
GO:0007254	JNK cascade	9.479753e-5
GO:0008652	cellular amino acid biosynthetic process	9.538989e-5
GO:0009593	detection of chemical stimulus	9.715558e-5
GO:0035050	embryonic heart tube development	9.779142e-5
GO:0009749	response to glucose stimulus	9.806076e-5
GO:0072511	divalent inorganic cation transport	9.884844e-5
GO:0002339	B cell selection	9.905809e-5
GO:0030168	platelet activation	9.912839e-5
GO:0097150	neuronal stem cell maintenance	9.927539e-5
GO:0035887	aortic smooth muscle cell differentiation	9.927539e-5
GO:0060509	Type I pneumocyte differentiation	9.955722e-5
GO:0045080	positive regulation of chemokine biosynthetic process	9.955722e-5
GO:0060789	hair follicle placode formation	1.010464e-4
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.011385e-4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.017972e-4
GO:0048863	stem cell differentiation	1.025648e-4
GO:0046907	intracellular transport	1.049711e-4
GO:0030036	actin cytoskeleton organization	1.067321e-4
GO:0042472	inner ear morphogenesis	1.067518e-4
GO:0001776	leukocyte homeostasis	1.069307e-4
GO:0009582	detection of abiotic stimulus	1.074537e-4
GO:0006612	protein targeting to membrane	1.083165e-4
GO:0001913	T cell mediated cytotoxicity	1.111927e-4
GO:0042063	gliogenesis	1.151929e-4
GO:0048598	embryonic morphogenesis	1.196580e-4
GO:0033273	response to vitamin	1.213768e-4