Novel motif:11

name:	motif11_GCGANT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0090304	nucleic acid metabolic process	9.785648e-14
GO:0016070	RNA metabolic process	2.177483e-12
GO:0010467	gene expression	2.363743e-11
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	4.207133e-11
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	2.650987e-10
GO:0032774	RNA biosynthetic process	4.453177e-10
GO:0034645	cellular macromolecule biosynthetic process	7.087149e-10
GO:0006351	transcription, DNA-dependent	9.989686e-10
GO:0090344	negative regulation of cell aging	3.873154e-9
GO:0009059	macromolecule biosynthetic process	8.082310e-9
GO:0018993	somatic sex determination	1.029644e-8
GO:0042703	menstruation	1.526232e-8
GO:0019101	female somatic sex determination	1.526232e-8
GO:0002074	extraocular skeletal muscle development	3.054101e-8
GO:0060976	coronary vasculature development	6.823395e-8
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.680827e-7
GO:0030262	apoptotic nuclear change	1.973230e-7
GO:0022601	menstrual cycle phase	2.170602e-7
GO:0006139	nucleobase-containing compound metabolic process	2.209934e-7
GO:0090305	nucleic acid phosphodiester bond hydrolysis	3.785952e-7
GO:0035470	positive regulation of vascular wound healing	3.920453e-7
GO:0000416	positive regulation of histone H3-K36 methylation	7.005150e-7
GO:0033326	cerebrospinal fluid secretion	8.586066e-7
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.170705e-6
GO:0071934	thiamine transmembrane transport	1.208312e-6
GO:0006308	DNA catabolic process	1.775098e-6
GO:0006369	termination of RNA polymerase II transcription	1.814142e-6
GO:0060430	lung saccule development	2.307360e-6
GO:0032472	Golgi calcium ion transport	2.647295e-6
GO:0030026	cellular manganese ion homeostasis	2.647295e-6
GO:0032468	Golgi calcium ion homeostasis	2.647295e-6
GO:0010719	negative regulation of epithelial to mesenchymal transition	2.721571e-6
GO:0010871	negative regulation of receptor biosynthetic process	2.759228e-6
GO:0090342	regulation of cell aging	3.110080e-6
GO:0000413	protein peptidyl-prolyl isomerization	3.150744e-6
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	4.068174e-6
GO:0042538	hyperosmotic salinity response	5.442172e-6
GO:0032912	negative regulation of transforming growth factor beta2 production	5.590633e-6
GO:0000414	regulation of histone H3-K36 methylation	1.020732e-5
GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process	1.042933e-5
GO:0010506	regulation of autophagy	1.368871e-5
GO:0016570	histone modification	1.429787e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.626791e-5
GO:0018872	arsonoacetate metabolic process	1.626791e-5
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.693741e-5
GO:0014014	negative regulation of gliogenesis	1.716524e-5
GO:0043923	positive regulation by host of viral transcription	1.717535e-5
GO:0031123	RNA 3'-end processing	1.768288e-5
GO:0090102	cochlea development	1.827081e-5
GO:0044260	cellular macromolecule metabolic process	2.025335e-5
GO:0016569	covalent chromatin modification	2.069942e-5
GO:0010721	negative regulation of cell development	2.591736e-5
GO:0000959	mitochondrial RNA metabolic process	2.633486e-5
GO:0048713	regulation of oligodendrocyte differentiation	3.063423e-5
GO:0060014	granulosa cell differentiation	3.257000e-5
GO:0003310	pancreatic A cell differentiation	3.413695e-5
GO:0048561	establishment of organ orientation	3.577544e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	3.838518e-5
GO:0030237	female sex determination	3.838518e-5
GO:0003148	outflow tract septum morphogenesis	4.428788e-5
GO:0060947	cardiac vascular smooth muscle cell differentiation	4.526061e-5
GO:0051252	regulation of RNA metabolic process	4.556728e-5
GO:0035886	vascular smooth muscle cell differentiation	5.791836e-5
GO:0060486	Clara cell differentiation	5.864098e-5
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	6.079300e-5
GO:0009404	toxin metabolic process	6.148042e-5
GO:0006355	regulation of transcription, DNA-dependent	6.966198e-5
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	7.364675e-5
GO:0065002	intracellular protein transmembrane transport	7.428523e-5
GO:0032042	mitochondrial DNA metabolic process	7.561485e-5
GO:0060980	cell migration involved in coronary vasculogenesis	7.566131e-5
GO:0035461	vitamin transmembrane transport	7.566131e-5
GO:0006302	double-strand break repair	7.627620e-5
GO:0060411	cardiac septum morphogenesis	8.083688e-5
GO:0090399	replicative senescence	8.154724e-5
GO:0000002	mitochondrial genome maintenance	8.584180e-5
GO:0000725	recombinational repair	9.288066e-5
GO:0000724	double-strand break repair via homologous recombination	9.491820e-5
GO:0006713	glucocorticoid catabolic process	9.833976e-5
GO:0006427	histidyl-tRNA aminoacylation	1.022055e-4
GO:0060712	spongiotrophoblast layer development	1.070824e-4
GO:0018293	protein-FAD linkage	1.075659e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.075659e-4
GO:0033523	histone H2B ubiquitination	1.079278e-4
GO:0071539	protein localization to centrosome	1.092384e-4
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.136020e-4
GO:0051890	regulation of cardioblast differentiation	1.136020e-4
GO:0022027	interkinetic nuclear migration	1.161655e-4
GO:0006513	protein monoubiquitination	1.176855e-4
GO:0000022	mitotic spindle elongation	1.177733e-4
GO:0071322	cellular response to carbohydrate stimulus	1.240380e-4
GO:0021759	globus pallidus development	1.295406e-4
GO:0006268	DNA unwinding involved in replication	1.379806e-4
GO:0042696	menarche	1.402571e-4
GO:0090303	positive regulation of wound healing	1.422469e-4
GO:0007141	male meiosis I	1.422469e-4
GO:0045892	negative regulation of transcription, DNA-dependent	1.473381e-4
GO:0090141	positive regulation of mitochondrial fission	1.579393e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.610869e-4
GO:0048752	semicircular canal morphogenesis	1.641598e-4
GO:0034198	cellular response to amino acid starvation	1.706971e-4
GO:0006281	DNA repair	1.746315e-4
GO:0030421	defecation	1.768894e-4
GO:0035356	cellular triglyceride homeostasis	1.768894e-4
GO:0003309	type B pancreatic cell differentiation	1.842121e-4
GO:0055012	ventricular cardiac muscle cell differentiation	2.004571e-4
GO:0071333	cellular response to glucose stimulus	2.015802e-4
GO:0032383	regulation of intracellular cholesterol transport	2.051591e-4
GO:0051891	positive regulation of cardioblast differentiation	2.058539e-4
GO:0003279	cardiac septum development	2.062908e-4
GO:0051253	negative regulation of RNA metabolic process	2.172424e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.256077e-4
GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	2.294442e-4
GO:0000715	nucleotide-excision repair, DNA damage recognition	2.371072e-4
GO:0046784	intronless viral mRNA export from host nucleus	2.399763e-4
GO:0060708	spongiotrophoblast differentiation	2.524990e-4
GO:0048664	neuron fate determination	2.650912e-4
GO:0002016	regulation of blood volume by renin-angiotensin	2.698269e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	2.730416e-4
GO:0018026	peptidyl-lysine monomethylation	2.780680e-4
GO:0060580	ventral spinal cord interneuron fate determination	2.809802e-4
GO:0003327	type B pancreatic cell fate commitment	2.809802e-4
GO:0003218	cardiac left ventricle formation	3.140122e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3.283591e-4
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	3.283591e-4
GO:0006844	acyl carnitine transport	3.398709e-4
GO:0018208	peptidyl-proline modification	3.464187e-4
GO:0060596	mammary placode formation	3.631804e-4
GO:0043631	RNA polyadenylation	3.775128e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	3.966898e-4
GO:0010390	histone monoubiquitination	3.993697e-4
GO:0010629	negative regulation of gene expression	4.203211e-4
GO:0021604	cranial nerve structural organization	4.325982e-4
GO:0045686	negative regulation of glial cell differentiation	4.353674e-4
GO:0032392	DNA geometric change	4.375969e-4
GO:0000236	mitotic prometaphase	4.663337e-4
GO:0051083	'de novo' cotranslational protein folding	4.667663e-4
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	4.701855e-4
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	4.701855e-4
GO:0043622	cortical microtubule organization	4.701855e-4
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	4.701855e-4
GO:0007092	activation of mitotic anaphase-promoting complex activity	4.701855e-4
GO:0030103	vasopressin secretion	4.701855e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	4.928205e-4
GO:0035845	photoreceptor cell outer segment organization	4.981679e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	4.981679e-4
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.009664e-4
GO:0009446	putrescine biosynthetic process	5.318934e-4
GO:2000615	regulation of histone H3-K9 acetylation	5.431450e-4
GO:0060510	Type II pneumocyte differentiation	6.036798e-4
GO:0003151	outflow tract morphogenesis	6.164186e-4
GO:0048714	positive regulation of oligodendrocyte differentiation	6.378048e-4
GO:0006481	C-terminal protein methylation	6.479560e-4
GO:0042984	regulation of amyloid precursor protein biosynthetic process	6.489600e-4
GO:0045685	regulation of glial cell differentiation	6.595789e-4
GO:0006378	mRNA polyadenylation	6.786361e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	6.873577e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6.876252e-4
GO:0031122	cytoplasmic microtubule organization	7.201044e-4
GO:0016574	histone ubiquitination	7.202207e-4
GO:0009086	methionine biosynthetic process	7.421434e-4
GO:0000966	RNA 5'-end processing	7.509299e-4
GO:0090140	regulation of mitochondrial fission	7.751763e-4
GO:0006289	nucleotide-excision repair	7.833264e-4
GO:0061084	negative regulation of protein refolding	7.851454e-4
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	7.886399e-4
GO:0016140	O-glycoside metabolic process	8.017807e-4
GO:0035115	embryonic forelimb morphogenesis	8.337700e-4
GO:0021612	facial nerve structural organization	8.642693e-4
GO:0043000	Golgi to plasma membrane CFTR protein transport	9.184677e-4
GO:0000375	RNA splicing, via transesterification reactions	9.199354e-4
GO:0006493	protein O-linked glycosylation	9.247099e-4
GO:0031124	mRNA 3'-end processing	9.298239e-4
GO:0070535	histone H2A K63-linked ubiquitination	9.729706e-4
GO:0046210	nitric oxide catabolic process	9.729706e-4
GO:0090346	cellular organofluorine metabolic process	9.729706e-4
GO:0043602	nitrate catabolic process	9.729706e-4
GO:0035621	ER to Golgi ceramide transport	9.729706e-4
GO:0042732	D-xylose metabolic process	9.729706e-4
GO:0030330	DNA damage response, signal transduction by p53 class mediator	9.881287e-4
GO:0006270	DNA-dependent DNA replication initiation	9.986338e-4
GO:0016926	protein desumoylation	1.008388e-3
GO:0048486	parasympathetic nervous system development	1.011177e-3
GO:0014013	regulation of gliogenesis	1.030502e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	1.049862e-3
GO:0010159	specification of organ position	1.086926e-3
GO:0070534	protein K63-linked ubiquitination	1.094629e-3
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	1.111756e-3
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	1.111838e-3
GO:0032446	protein modification by small protein conjugation	1.185843e-3
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	1.234204e-3
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	1.234204e-3
GO:0042711	maternal behavior	1.283081e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	1.306681e-3
GO:0002035	brain renin-angiotensin system	1.308918e-3
GO:0035117	embryonic arm morphogenesis	1.312225e-3
GO:0060412	ventricular septum morphogenesis	1.361174e-3
GO:0002115	store-operated calcium entry	1.408399e-3
GO:0046884	follicle-stimulating hormone secretion	1.409926e-3
GO:0032275	luteinizing hormone secretion	1.409926e-3
GO:0000729	DNA double-strand break processing	1.410167e-3
GO:0006264	mitochondrial DNA replication	1.464808e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	1.488647e-3
GO:0051865	protein autoubiquitination	1.514835e-3
GO:0061351	neural precursor cell proliferation	1.523224e-3
GO:0090224	regulation of spindle organization	1.528923e-3
GO:0070584	mitochondrion morphogenesis	1.557414e-3
GO:0010890	positive regulation of sequestering of triglyceride	1.572174e-3
GO:0006290	pyrimidine dimer repair	1.572174e-3
GO:0050779	RNA destabilization	1.572454e-3
GO:0000097	sulfur amino acid biosynthetic process	1.573519e-3
GO:0021666	rhombomere 5 formation	1.581101e-3
GO:0021660	rhombomere 3 formation	1.581101e-3
GO:0071105	response to interleukin-11	1.615777e-3
GO:0042946	glucoside transport	1.615777e-3
GO:0019358	nicotinate nucleotide salvage	1.615777e-3
GO:0023035	CD40 signaling pathway	1.615777e-3
GO:0032508	DNA duplex unwinding	1.674551e-3
GO:0043921	modulation by host of viral transcription	1.720203e-3
GO:0021599	abducens nerve formation	1.818490e-3
GO:0007634	optokinetic behavior	1.818490e-3
GO:0042823	pyridoxal phosphate biosynthetic process	1.901625e-3
GO:0019348	dolichol metabolic process	1.901625e-3
GO:0007174	epidermal growth factor catabolic process	1.901625e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.901625e-3
GO:2000620	positive regulation of histone H4-K16 acetylation	1.906015e-3
GO:2000617	positive regulation of histone H3-K9 acetylation	1.906015e-3
GO:0070625	zymogen granule exocytosis	1.906015e-3
GO:0070512	positive regulation of histone H4-K20 methylation	1.906015e-3
GO:0030505	inorganic diphosphate transport	1.910346e-3
GO:0035566	regulation of metanephros size	1.919203e-3
GO:0015870	acetylcholine transport	1.919203e-3
GO:0010701	positive regulation of norepinephrine secretion	1.919203e-3
GO:0016925	protein sumoylation	1.923835e-3
GO:0061001	regulation of dendritic spine morphogenesis	1.953489e-3
GO:2000465	regulation of glycogen (starch) synthase activity	2.057173e-3
GO:0050746	regulation of lipoprotein metabolic process	2.269619e-3
GO:0021783	preganglionic parasympathetic nervous system development	2.272114e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	2.292347e-3
GO:0019509	L-methionine salvage from methylthioadenosine	2.292347e-3
GO:0042723	thiamine-containing compound metabolic process	2.294552e-3
GO:0006379	mRNA cleavage	2.296149e-3
GO:0021602	cranial nerve morphogenesis	2.335646e-3
GO:0060876	semicircular canal formation	2.351237e-3
GO:0048712	negative regulation of astrocyte differentiation	2.423348e-3
GO:0072300	positive regulation of metanephric glomerulus development	2.501786e-3
GO:0021603	cranial nerve formation	2.505235e-3
GO:0060253	negative regulation of glial cell proliferation	2.551620e-3
GO:0010735	positive regulation of transcription via serum response element binding	2.570850e-3
GO:0006348	chromatin silencing at telomere	2.571621e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	2.585008e-3
GO:0016567	protein ubiquitination	2.659723e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	2.780700e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	2.780700e-3
GO:0042843	D-xylose catabolic process	2.801690e-3
GO:0051571	positive regulation of histone H3-K4 methylation	2.826628e-3
GO:0003281	ventricular septum development	2.853926e-3
GO:0060872	semicircular canal development	2.865791e-3
GO:0072086	specification of loop of Henle identity	2.874787e-3
GO:0061013	regulation of mRNA catabolic process	2.913656e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	2.913656e-3
GO:0016568	chromatin modification	2.980253e-3
GO:0043697	cell dedifferentiation	3.006954e-3
GO:2000773	negative regulation of cellular senescence	3.006954e-3
GO:0030953	astral microtubule organization	3.006954e-3
GO:0051645	Golgi localization	3.071631e-3
GO:0006421	asparaginyl-tRNA aminoacylation	3.071631e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	3.077267e-3
GO:0002017	regulation of blood volume by renal aldosterone	3.077267e-3
GO:0085020	protein K6-linked ubiquitination	3.077688e-3
GO:0048102	autophagic cell death	3.077688e-3
GO:0045116	protein neddylation	3.077688e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	3.105485e-3
GO:0007158	neuron cell-cell adhesion	3.113728e-3
GO:0007501	mesodermal cell fate specification	3.138047e-3
GO:0001678	cellular glucose homeostasis	3.141660e-3
GO:0001941	postsynaptic membrane organization	3.194506e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	3.227265e-3
GO:0071476	cellular hypotonic response	3.249408e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	3.256630e-3
GO:0015872	dopamine transport	3.288828e-3
GO:0060713	labyrinthine layer morphogenesis	3.337052e-3
GO:0043508	negative regulation of JUN kinase activity	3.352366e-3
GO:0090103	cochlea morphogenesis	3.364970e-3
GO:0042073	intraflagellar transport	3.483672e-3
GO:0009067	aspartate family amino acid biosynthetic process	3.582195e-3
GO:0035928	rRNA import into mitochondrion	3.586770e-3
GO:0000422	mitochondrion degradation	3.611667e-3
GO:0033182	regulation of histone ubiquitination	3.629010e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	3.629010e-3
GO:0006666	3-keto-sphinganine metabolic process	3.629010e-3
GO:0043401	steroid hormone mediated signaling pathway	3.707833e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	3.742288e-3
GO:0048291	isotype switching to IgG isotypes	3.742288e-3
GO:0002368	B cell cytokine production	3.742288e-3
GO:0006555	methionine metabolic process	3.751616e-3
GO:0060039	pericardium development	3.756068e-3
GO:0051973	positive regulation of telomerase activity	3.808871e-3
GO:0048388	endosomal lumen acidification	3.896471e-3
GO:0003326	pancreatic A cell fate commitment	3.896471e-3
GO:0003329	pancreatic PP cell fate commitment	3.896471e-3
GO:0021542	dentate gyrus development	3.920734e-3
GO:0007140	male meiosis	3.937474e-3
GO:0030488	tRNA methylation	3.987492e-3
GO:0015884	folic acid transport	3.991928e-3
GO:0032202	telomere assembly	3.991928e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	4.033869e-3
GO:0042596	fear response	4.067954e-3
GO:0035357	peroxisome proliferator activated receptor signaling pathway	4.111589e-3
GO:0033057	multicellular organismal reproductive behavior	4.155046e-3
GO:0035441	cell migration involved in vasculogenesis	4.169912e-3
GO:0060592	mammary gland formation	4.230558e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	4.232796e-3
GO:0060998	regulation of dendritic spine development	4.361709e-3
GO:0009890	negative regulation of biosynthetic process	4.456602e-3
GO:0048691	positive regulation of axon extension involved in regeneration	4.479035e-3
GO:0019056	modulation by virus of host transcription	4.479035e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.564661e-3
GO:0007181	transforming growth factor beta receptor complex assembly	4.565908e-3
GO:0030520	estrogen receptor signaling pathway	4.581348e-3
GO:0046602	regulation of mitotic centrosome separation	4.609794e-3
GO:0030388	fructose 1,6-bisphosphate metabolic process	4.685505e-3
GO:0090239	regulation of histone H4 acetylation	4.765613e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	4.893474e-3
GO:0006501	C-terminal protein lipidation	4.982199e-3
GO:0007231	osmosensory signaling pathway	5.042351e-3
GO:0034641	cellular nitrogen compound metabolic process	5.075903e-3
GO:0071104	response to interleukin-9	5.081615e-3
GO:0045875	negative regulation of sister chromatid cohesion	5.081615e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	5.173569e-3
GO:0048532	anatomical structure arrangement	5.229279e-3
GO:0051276	chromosome organization	5.298003e-3
GO:0003181	atrioventricular valve morphogenesis	5.320049e-3
GO:0021571	rhombomere 5 development	5.331188e-3
GO:0051569	regulation of histone H3-K4 methylation	5.423888e-3
GO:0050748	negative regulation of lipoprotein metabolic process	5.447468e-3
GO:2000772	regulation of cellular senescence	5.504066e-3
GO:0055014	atrial cardiac muscle cell development	5.529754e-3
GO:0060977	coronary vasculature morphogenesis	5.529754e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	5.544243e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	5.551219e-3
GO:0072331	signal transduction by p53 class mediator	5.640510e-3
GO:0001710	mesodermal cell fate commitment	5.689626e-3
GO:0001764	neuron migration	5.898398e-3
GO:0009304	tRNA transcription	5.911965e-3
GO:0002065	columnar/cuboidal epithelial cell differentiation	5.933224e-3
GO:0060383	positive regulation of DNA strand elongation	5.935611e-3
GO:0042694	muscle cell fate specification	5.935611e-3
GO:0051660	establishment of centrosome localization	5.935611e-3
GO:0042335	cuticle development	5.935611e-3
GO:0021540	corpus callosum morphogenesis	5.935611e-3
GO:0010986	positive regulation of lipoprotein particle clearance	5.935611e-3
GO:0009996	negative regulation of cell fate specification	6.042738e-3
GO:0006999	nuclear pore organization	6.087458e-3
GO:0016048	detection of temperature stimulus	6.138037e-3
GO:0021610	facial nerve morphogenesis	6.139089e-3
GO:0021895	cerebral cortex neuron differentiation	6.171627e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	6.219479e-3
GO:0010468	regulation of gene expression	6.244949e-3
GO:0042228	interleukin-8 biosynthetic process	6.285050e-3
GO:0000088	mitotic prophase	6.285050e-3
GO:0033342	negative regulation of collagen binding	6.285050e-3
GO:0008380	RNA splicing	6.294850e-3
GO:0046333	octopamine metabolic process	6.331215e-3
GO:0042309	homoiothermy	6.331215e-3
GO:0046950	cellular ketone body metabolic process	6.331380e-3
GO:0007422	peripheral nervous system development	6.358094e-3
GO:0034770	histone H4-K20 methylation	6.408837e-3
GO:0003206	cardiac chamber morphogenesis	6.551617e-3
GO:0097039	protein linear polyubiquitination	6.641896e-3
GO:0002678	positive regulation of chronic inflammatory response	6.786646e-3
GO:0035136	forelimb morphogenesis	6.899134e-3
GO:0061014	positive regulation of mRNA catabolic process	7.087373e-3
GO:0003323	type B pancreatic cell development	7.096367e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.293166e-3
GO:0070407	oxidation-dependent protein catabolic process	7.318351e-3
GO:0051106	positive regulation of DNA ligation	7.318351e-3
GO:2000252	negative regulation of feeding behavior	7.318351e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	7.318351e-3
GO:0019061	uncoating of virus	7.318351e-3
GO:0042414	epinephrine metabolic process	7.318351e-3
GO:0043456	regulation of pentose-phosphate shunt	7.341282e-3
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	7.341282e-3
GO:0035166	post-embryonic hemopoiesis	7.418881e-3
GO:0090234	regulation of kinetochore assembly	7.504813e-3
GO:0090169	regulation of spindle assembly	7.504813e-3
GO:0021846	cell proliferation in forebrain	7.536632e-3
GO:0006853	carnitine shuttle	7.672062e-3
GO:0006479	protein methylation	7.682371e-3
GO:2000119	negative regulation of sodium-dependent phosphate transport	7.804236e-3
GO:0034699	response to luteinizing hormone stimulus	7.804236e-3
GO:0008295	spermidine biosynthetic process	7.804236e-3
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	8.210944e-3
GO:0009443	pyridoxal 5'-phosphate salvage	8.210944e-3
GO:0042989	sequestering of actin monomers	8.275211e-3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	8.435862e-3
GO:0060706	cell differentiation involved in embryonic placenta development	8.441532e-3
GO:0071425	hemopoietic stem cell proliferation	8.525532e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	8.568670e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	8.568670e-3
GO:0032543	mitochondrial translation	8.609603e-3
GO:0002209	behavioral defense response	8.628102e-3
GO:0035721	intraflagellar retrograde transport	8.719202e-3
GO:0051647	nucleus localization	8.728723e-3
GO:0000738	DNA catabolic process, exonucleolytic	8.736168e-3
GO:0021562	vestibulocochlear nerve development	9.033058e-3
GO:0034214	protein hexamerization	9.173304e-3
GO:0000726	non-recombinational repair	9.207801e-3
GO:0034695	response to prostaglandin E stimulus	9.418741e-3
GO:0050774	negative regulation of dendrite morphogenesis	9.819198e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	9.909989e-3
GO:0051457	maintenance of protein location in nucleus	9.980167e-3
GO:0060304	regulation of phosphatidylinositol dephosphorylation	1.011353e-2
GO:0071279	cellular response to cobalt ion	1.011353e-2
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	1.011353e-2
GO:0032074	negative regulation of nuclease activity	1.011353e-2
GO:0031119	tRNA pseudouridine synthesis	1.011353e-2
GO:0010637	negative regulation of mitochondrial fusion	1.011353e-2
GO:0003416	endochondral bone growth	1.032119e-2
GO:0010560	positive regulation of glycoprotein biosynthetic process	1.034111e-2
GO:0032861	activation of Rap GTPase activity	1.057973e-2
GO:0018393	internal peptidyl-lysine acetylation	1.058234e-2
GO:0071985	multivesicular body sorting pathway	1.077582e-2
GO:0018022	peptidyl-lysine methylation	1.077582e-2
GO:0060648	mammary gland bud morphogenesis	1.098045e-2
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	1.098045e-2
GO:0048663	neuron fate commitment	1.102541e-2
GO:0001732	formation of translation initiation complex	1.112184e-2
GO:0032911	negative regulation of transforming growth factor beta1 production	1.117039e-2
GO:0010626	negative regulation of Schwann cell proliferation	1.119484e-2
GO:0046755	non-lytic virus budding	1.124498e-2
GO:0090219	negative regulation of lipid kinase activity	1.146707e-2
GO:0006499	N-terminal protein myristoylation	1.146707e-2
GO:0042631	cellular response to water deprivation	1.146707e-2
GO:0045739	positive regulation of DNA repair	1.157296e-2
GO:0015842	synaptic vesicle amine transport	1.173106e-2
GO:0035425	autocrine signaling	1.173106e-2
GO:0034498	early endosome to Golgi transport	1.188421e-2
GO:0030302	deoxynucleotide transport	1.188421e-2
GO:0060742	epithelial cell differentiation involved in prostate gland development	1.190793e-2
GO:0006261	DNA-dependent DNA replication	1.217577e-2
GO:0003166	bundle of His development	1.217960e-2
GO:0060687	regulation of branching involved in prostate gland morphogenesis	1.236146e-2
GO:0045819	positive regulation of glycogen catabolic process	1.239544e-2
GO:0021561	facial nerve development	1.257756e-2
GO:0003417	growth plate cartilage development	1.269156e-2
GO:0045403	negative regulation of interleukin-4 biosynthetic process	1.273069e-2
GO:0034351	negative regulation of glial cell apoptosis	1.273069e-2
GO:0060377	negative regulation of mast cell differentiation	1.273069e-2
GO:0002295	T-helper cell lineage commitment	1.273069e-2
GO:0003195	tricuspid valve formation	1.273069e-2
GO:0003192	mitral valve formation	1.273069e-2
GO:0001662	behavioral fear response	1.275369e-2
GO:0046605	regulation of centrosome cycle	1.301079e-2
GO:0072081	specification of nephron tubule identity	1.312472e-2
GO:0050768	negative regulation of neurogenesis	1.328083e-2
GO:0044249	cellular biosynthetic process	1.331504e-2
GO:0034644	cellular response to UV	1.332719e-2
GO:0018394	peptidyl-lysine acetylation	1.340576e-2
GO:0060669	embryonic placenta morphogenesis	1.344214e-2
GO:0032224	positive regulation of synaptic transmission, cholinergic	1.377938e-2
GO:0046939	nucleotide phosphorylation	1.383665e-2
GO:0018027	peptidyl-lysine dimethylation	1.386891e-2
GO:0032203	telomere formation via telomerase	1.386891e-2
GO:0005981	regulation of glycogen catabolic process	1.399574e-2
GO:0035435	phosphate ion transmembrane transport	1.409870e-2
GO:0002118	aggressive behavior	1.410381e-2
GO:0010950	positive regulation of endopeptidase activity	1.410381e-2
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1.420917e-2
GO:0010266	response to vitamin B1	1.420917e-2
GO:0090129	positive regulation of synapse maturation	1.422413e-2
GO:0006686	sphingomyelin biosynthetic process	1.426252e-2
GO:0071866	negative regulation of apoptosis in bone marrow	1.431815e-2
GO:0071864	positive regulation of cell proliferation in bone marrow	1.431815e-2
GO:0071482	cellular response to light stimulus	1.445753e-2
GO:0006595	polyamine metabolic process	1.445753e-2
GO:0031327	negative regulation of cellular biosynthetic process	1.496942e-2
GO:0042418	epinephrine biosynthetic process	1.497529e-2
GO:0042780	tRNA 3'-end processing	1.497529e-2
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	1.497529e-2
GO:0035852	horizontal cell localization	1.497529e-2
GO:0048855	adenohypophysis morphogenesis	1.497529e-2
GO:0031118	rRNA pseudouridine synthesis	1.497529e-2
GO:0006585	dopamine biosynthetic process from tyrosine	1.497529e-2
GO:0035502	metanephric ureteric bud development	1.497529e-2
GO:0035846	oviduct epithelium development	1.497529e-2
GO:0035849	nephric duct elongation	1.497529e-2
GO:0035847	uterine epithelium development	1.497529e-2
GO:0035090	maintenance of apical/basal cell polarity	1.526457e-2
GO:0061302	smooth muscle cell-matrix adhesion	1.534457e-2
GO:0045472	response to ether	1.534457e-2
GO:0032205	negative regulation of telomere maintenance	1.543315e-2
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	1.545530e-2
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	1.545530e-2
GO:0035635	entry of bacterium into host cell	1.545530e-2
GO:0046358	butyrate biosynthetic process	1.545530e-2
GO:0033566	gamma-tubulin complex localization	1.545530e-2
GO:0090128	regulation of synapse maturation	1.578579e-2
GO:0018410	C-terminal protein amino acid modification	1.591586e-2
GO:0046174	polyol catabolic process	1.611574e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006396	RNA processing	1.047096e-12
GO:0051891	positive regulation of cardioblast differentiation	4.999865e-10
GO:0006397	mRNA processing	1.497584e-9
GO:0008380	RNA splicing	1.676715e-9
GO:0016071	mRNA metabolic process	8.980478e-9
GO:0051890	regulation of cardioblast differentiation	1.303776e-8
GO:0006268	DNA unwinding involved in replication	1.520012e-8
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	9.315404e-8
GO:0090304	nucleic acid metabolic process	1.005139e-7
GO:0032508	DNA duplex unwinding	1.585576e-7
GO:0032392	DNA geometric change	2.977910e-7
GO:0032912	negative regulation of transforming growth factor beta2 production	3.149625e-7
GO:0006540	glutamate decarboxylation to succinate	3.390562e-7
GO:0006261	DNA-dependent DNA replication	4.471442e-7
GO:0022402	cell cycle process	5.507341e-7
GO:0031508	centromeric heterochromatin formation	6.524530e-7
GO:0045666	positive regulation of neuron differentiation	7.570158e-7
GO:0016070	RNA metabolic process	7.673208e-7
GO:0003309	type B pancreatic cell differentiation	8.197456e-7
GO:0010467	gene expression	1.262798e-6
GO:0006260	DNA replication	1.352369e-6
GO:0090234	regulation of kinetochore assembly	1.574817e-6
GO:0090169	regulation of spindle assembly	1.574817e-6
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.634354e-6
GO:0060045	positive regulation of cardiac muscle cell proliferation	1.922301e-6
GO:0085020	protein K6-linked ubiquitination	2.113415e-6
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	2.796691e-6
GO:0042254	ribosome biogenesis	2.934493e-6
GO:0000086	G2/M transition of mitotic cell cycle	3.000624e-6
GO:0000278	mitotic cell cycle	3.155063e-6
GO:0042136	neurotransmitter biosynthetic process	3.239917e-6
GO:0060043	regulation of cardiac muscle cell proliferation	3.992155e-6
GO:0030513	positive regulation of BMP signaling pathway	4.536171e-6
GO:0007493	endodermal cell fate determination	4.608369e-6
GO:0051726	regulation of cell cycle	5.083899e-6
GO:0022403	cell cycle phase	9.043701e-6
GO:0006297	nucleotide-excision repair, DNA gap filling	9.218843e-6
GO:0007141	male meiosis I	1.178817e-5
GO:0090231	regulation of spindle checkpoint	1.193761e-5
GO:0000080	G1 phase of mitotic cell cycle	1.204441e-5
GO:0046853	inositol or phosphatidylinositol phosphorylation	1.368831e-5
GO:0006538	glutamate catabolic process	1.730079e-5
GO:0031577	spindle checkpoint	1.998747e-5
GO:0035621	ER to Golgi ceramide transport	2.078085e-5
GO:0003310	pancreatic A cell differentiation	2.212185e-5
GO:0006139	nucleobase-containing compound metabolic process	2.220628e-5
GO:0016072	rRNA metabolic process	2.382716e-5
GO:0061013	regulation of mRNA catabolic process	2.550978e-5
GO:0000726	non-recombinational repair	2.800215e-5
GO:0021562	vestibulocochlear nerve development	3.231594e-5
GO:0045931	positive regulation of mitotic cell cycle	3.268577e-5
GO:0090193	positive regulation of glomerulus development	3.517402e-5
GO:0060947	cardiac vascular smooth muscle cell differentiation	4.208364e-5
GO:0060795	cell fate commitment involved in formation of primary germ layers	4.225463e-5
GO:0006657	CDP-choline pathway	4.373246e-5
GO:0055021	regulation of cardiac muscle tissue growth	4.659277e-5
GO:0022613	ribonucleoprotein complex biogenesis	4.756634e-5
GO:0035886	vascular smooth muscle cell differentiation	5.040265e-5
GO:0071169	establishment of protein localization to chromatin	5.584497e-5
GO:0045078	positive regulation of interferon-gamma biosynthetic process	5.710903e-5
GO:0044265	cellular macromolecule catabolic process	5.780036e-5
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	5.979212e-5
GO:0033031	positive regulation of neutrophil apoptosis	6.301936e-5
GO:0070165	positive regulation of adiponectin secretion	6.301936e-5
GO:0006308	DNA catabolic process	6.840239e-5
GO:0071843	cellular component biogenesis at cellular level	7.671880e-5
GO:0045072	regulation of interferon-gamma biosynthetic process	7.917338e-5
GO:0007049	cell cycle	9.324830e-5
GO:0003148	outflow tract septum morphogenesis	9.387677e-5
GO:0051329	interphase of mitotic cell cycle	1.013098e-4
GO:0032465	regulation of cytokinesis	1.021745e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.093012e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.093012e-4
GO:0039003	pronephric field specification	1.093012e-4
GO:0001711	endodermal cell fate commitment	1.103682e-4
GO:0034661	ncRNA catabolic process	1.170912e-4
GO:0034446	substrate adhesion-dependent cell spreading	1.176136e-4
GO:0051030	snRNA transport	1.190684e-4
GO:0046416	D-amino acid metabolic process	1.190684e-4
GO:0060411	cardiac septum morphogenesis	1.243796e-4
GO:0072300	positive regulation of metanephric glomerulus development	1.386563e-4
GO:0051318	G1 phase	1.493556e-4
GO:0006364	rRNA processing	1.561927e-4
GO:0003279	cardiac septum development	1.645842e-4
GO:0032911	negative regulation of transforming growth factor beta1 production	1.673001e-4
GO:0072003	kidney rudiment formation	1.708894e-4
GO:0014010	Schwann cell proliferation	1.708894e-4
GO:0018243	protein O-linked glycosylation via threonine	1.809295e-4
GO:0018242	protein O-linked glycosylation via serine	1.809295e-4
GO:0051297	centrosome organization	1.810631e-4
GO:0019428	allantoin biosynthetic process	1.957979e-4
GO:0006366	transcription from RNA polymerase II promoter	1.996621e-4
GO:0051325	interphase	2.041274e-4
GO:0061360	optic chiasma development	2.204943e-4
GO:2000597	positive regulation of optic nerve formation	2.204943e-4
GO:0021650	vestibulocochlear nerve formation	2.204943e-4
GO:0035799	ureter maturation	2.204943e-4
GO:0021633	optic nerve structural organization	2.204943e-4
GO:0001709	cell fate determination	2.231171e-4
GO:0032908	regulation of transforming growth factor beta1 production	2.295567e-4
GO:0006259	DNA metabolic process	2.401689e-4
GO:0009452	RNA capping	2.441800e-4
GO:0000237	leptotene	2.533517e-4
GO:0072205	metanephric collecting duct development	2.613612e-4
GO:0070534	protein K63-linked ubiquitination	2.659318e-4
GO:0044260	cellular macromolecule metabolic process	2.684548e-4
GO:0070830	tight junction assembly	2.906320e-4
GO:0090224	regulation of spindle organization	3.238779e-4
GO:0046491	L-methylmalonyl-CoA metabolic process	3.325888e-4
GO:0016078	tRNA catabolic process	3.325888e-4
GO:0001682	tRNA 5'-leader removal	3.325888e-4
GO:0055024	regulation of cardiac muscle tissue development	3.387387e-4
GO:0021884	forebrain neuron development	3.459446e-4
GO:0006413	translational initiation	3.477753e-4
GO:0048645	organ formation	3.484147e-4
GO:0034587	piRNA metabolic process	3.726247e-4
GO:0003197	endocardial cushion development	3.746132e-4
GO:0007099	centriole replication	3.840955e-4
GO:0071034	CUT catabolic process	3.843990e-4
GO:0048286	lung alveolus development	3.849324e-4
GO:0071173	spindle assembly checkpoint	3.882960e-4
GO:2000036	regulation of stem cell maintenance	3.997796e-4
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	4.251243e-4
GO:0071777	positive regulation of cell cycle cytokinesis	4.612482e-4
GO:0006289	nucleotide-excision repair	4.659006e-4
GO:0060575	intestinal epithelial cell differentiation	4.672281e-4
GO:0050668	positive regulation of homocysteine metabolic process	4.700843e-4
GO:0045963	negative regulation of dopamine metabolic process	4.700843e-4
GO:0001704	formation of primary germ layer	4.707828e-4
GO:0007140	male meiosis	4.795595e-4
GO:0010564	regulation of cell cycle process	5.299098e-4
GO:0070079	histone H4-R3 demethylation	5.319094e-4
GO:0070078	histone H3-R2 demethylation	5.319094e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	5.319094e-4
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	5.319094e-4
GO:0022417	protein maturation by protein folding	5.319094e-4
GO:0046882	negative regulation of follicle-stimulating hormone secretion	5.356314e-4
GO:0046426	negative regulation of JAK-STAT cascade	5.418390e-4
GO:0031023	microtubule organizing center organization	5.422172e-4
GO:0035987	endodermal cell differentiation	5.438966e-4
GO:0016926	protein desumoylation	5.548893e-4
GO:0006405	RNA export from nucleus	5.682688e-4
GO:0034470	ncRNA processing	6.293750e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	6.299829e-4
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	6.368052e-4
GO:0007067	mitosis	6.462328e-4
GO:0000087	M phase of mitotic cell cycle	6.556119e-4
GO:0000279	M phase	7.297487e-4
GO:0000729	DNA double-strand break processing	7.395326e-4
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	7.476070e-4
GO:0014047	glutamate secretion	7.587529e-4
GO:0008608	attachment of spindle microtubules to kinetochore	7.667455e-4
GO:0051176	positive regulation of sulfur metabolic process	7.863915e-4
GO:0031055	chromatin remodeling at centromere	7.911064e-4
GO:0021603	cranial nerve formation	7.959298e-4
GO:0048285	organelle fission	8.140105e-4
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	8.824365e-4
GO:0030510	regulation of BMP signaling pathway	8.976776e-4
GO:0001835	blastocyst hatching	9.667546e-4
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.003660e-3
GO:0042360	vitamin E metabolic process	1.008534e-3
GO:0002638	negative regulation of immunoglobulin production	1.024448e-3
GO:0001811	negative regulation of type I hypersensitivity	1.024448e-3
GO:0031442	positive regulation of mRNA 3'-end processing	1.024587e-3
GO:0061014	positive regulation of mRNA catabolic process	1.070566e-3
GO:0035425	autocrine signaling	1.100482e-3
GO:0003151	outflow tract morphogenesis	1.111051e-3
GO:0070194	synaptonemal complex disassembly	1.129681e-3
GO:0070179	D-serine biosynthetic process	1.129681e-3
GO:0043297	apical junction assembly	1.139637e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.155009e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.171181e-3
GO:0072594	establishment of protein localization to organelle	1.182203e-3
GO:0051298	centrosome duplication	1.200162e-3
GO:0007389	pattern specification process	1.206331e-3
GO:0071156	regulation of cell cycle arrest	1.210863e-3
GO:0051457	maintenance of protein location in nucleus	1.225996e-3
GO:0019377	glycolipid catabolic process	1.246680e-3
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.354972e-3
GO:0050779	RNA destabilization	1.396527e-3
GO:0016075	rRNA catabolic process	1.396527e-3
GO:0060420	regulation of heart growth	1.462229e-3
GO:0071635	negative regulation of transforming growth factor beta production	1.499947e-3
GO:0021758	putamen development	1.541633e-3
GO:0021757	caudate nucleus development	1.541633e-3
GO:0006511	ubiquitin-dependent protein catabolic process	1.542842e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	1.549101e-3
GO:0030262	apoptotic nuclear change	1.560970e-3
GO:0090192	regulation of glomerulus development	1.589698e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	1.603770e-3
GO:0034660	ncRNA metabolic process	1.632910e-3
GO:0071174	mitotic cell cycle spindle checkpoint	1.651917e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.660239e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.733009e-3
GO:0007346	regulation of mitotic cell cycle	1.761452e-3
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	1.765805e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.765805e-3
GO:0021797	forebrain anterior/posterior pattern specification	1.779041e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.844715e-3
GO:0032060	bleb assembly	1.885207e-3
GO:0001706	endoderm formation	1.901951e-3
GO:0009057	macromolecule catabolic process	1.923128e-3
GO:0030163	protein catabolic process	1.925942e-3
GO:0007501	mesodermal cell fate specification	1.987888e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.987888e-3
GO:0042268	regulation of cytolysis	2.021401e-3
GO:0071158	positive regulation of cell cycle arrest	2.099781e-3
GO:0006306	DNA methylation	2.109005e-3
GO:0032467	positive regulation of cytokinesis	2.170388e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	2.170388e-3
GO:0051145	smooth muscle cell differentiation	2.226367e-3
GO:0090286	cytoskeletal anchoring at nuclear membrane	2.271357e-3
GO:0034441	plasma lipoprotein particle oxidation	2.276637e-3
GO:0001555	oocyte growth	2.276637e-3
GO:0035330	regulation of hippo signaling cascade	2.326089e-3
GO:0030521	androgen receptor signaling pathway	2.341503e-3
GO:0090042	tubulin deacetylation	2.405533e-3
GO:0070846	Hsp90 deacetylation	2.405533e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.405533e-3
GO:0006780	uroporphyrinogen III biosynthetic process	2.405533e-3
GO:0032365	intracellular lipid transport	2.454012e-3
GO:0019941	modification-dependent protein catabolic process	2.463579e-3
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	2.538819e-3
GO:0050685	positive regulation of mRNA processing	2.627610e-3
GO:0043484	regulation of RNA splicing	2.705217e-3
GO:0007619	courtship behavior	2.718576e-3
GO:0071108	protein K48-linked deubiquitination	2.823018e-3
GO:0006406	mRNA export from nucleus	2.845524e-3
GO:0043632	modification-dependent macromolecule catabolic process	2.888676e-3
GO:0060649	mammary gland bud elongation	2.899561e-3
GO:0060659	nipple sheath formation	2.899561e-3
GO:0060003	copper ion export	2.899561e-3
GO:0015677	copper ion import	2.899561e-3
GO:0006921	cellular component disassembly involved in apoptosis	2.920447e-3
GO:0032277	negative regulation of gonadotropin secretion	2.932595e-3
GO:0031584	activation of phospholipase D activity	2.932595e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	2.957803e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	3.018220e-3
GO:0035852	horizontal cell localization	3.018220e-3
GO:0035849	nephric duct elongation	3.018220e-3
GO:0035846	oviduct epithelium development	3.018220e-3
GO:0035847	uterine epithelium development	3.018220e-3
GO:0046605	regulation of centrosome cycle	3.142686e-3
GO:0006493	protein O-linked glycosylation	3.203131e-3
GO:0003406	retinal pigment epithelium development	3.264775e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	3.475975e-3
GO:0021516	dorsal spinal cord development	3.663167e-3
GO:0019376	galactolipid catabolic process	3.694655e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	3.694655e-3
GO:0006408	snRNA export from nucleus	3.830644e-3
GO:0002663	positive regulation of B cell tolerance induction	3.944121e-3
GO:0021549	cerebellum development	3.967163e-3
GO:0090399	replicative senescence	4.009511e-3
GO:0014051	gamma-aminobutyric acid secretion	4.083635e-3
GO:0072520	seminiferous tubule development	4.265834e-3
GO:0071476	cellular hypotonic response	4.265834e-3
GO:0035566	regulation of metanephros size	4.265834e-3
GO:0006302	double-strand break repair	4.290081e-3
GO:0065004	protein-DNA complex assembly	4.399407e-3
GO:0046102	inosine metabolic process	4.516142e-3
GO:0035519	protein K29-linked ubiquitination	4.516142e-3
GO:0006613	cotranslational protein targeting to membrane	4.545796e-3
GO:0051973	positive regulation of telomerase activity	4.561021e-3
GO:0060658	nipple morphogenesis	4.561021e-3
GO:0045918	negative regulation of cytolysis	4.561021e-3
GO:0060540	diaphragm morphogenesis	4.690855e-3
GO:0060464	lung lobe formation	4.690855e-3
GO:0072289	metanephric nephron tubule formation	4.718778e-3
GO:0070625	zymogen granule exocytosis	4.768594e-3
GO:0044314	protein K27-linked ubiquitination	4.768594e-3
GO:0070163	regulation of adiponectin secretion	4.768594e-3
GO:0000059	protein import into nucleus, docking	4.768594e-3
GO:0018214	protein carboxylation	4.768594e-3
GO:0034641	cellular nitrogen compound metabolic process	4.835156e-3
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.086506e-3
GO:0071218	cellular response to misfolded protein	5.086506e-3
GO:0042667	auditory receptor cell fate specification	5.120654e-3
GO:0045609	positive regulation of auditory receptor cell differentiation	5.120654e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	5.120654e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	5.120654e-3
GO:0034230	enkephalin processing	5.120654e-3
GO:0034231	islet amyloid polypeptide processing	5.120654e-3
GO:0003259	cardioblast anterior-lateral migration	5.120654e-3
GO:0003236	sinus venosus morphogenesis	5.120654e-3
GO:0003210	cardiac atrium formation	5.120654e-3
GO:0033152	immunoglobulin V(D)J recombination	5.165545e-3
GO:0023019	signal transduction involved in regulation of gene expression	5.262562e-3
GO:0031440	regulation of mRNA 3'-end processing	5.408037e-3
GO:0007398	ectoderm development	5.412675e-3
GO:0022617	extracellular matrix disassembly	5.549513e-3
GO:0051496	positive regulation of stress fiber assembly	5.770840e-3
GO:0072215	regulation of metanephros development	6.141467e-3
GO:0032507	maintenance of protein location in cell	6.164492e-3
GO:0044257	cellular protein catabolic process	6.173666e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	6.194198e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	6.224474e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	6.224474e-3
GO:0001705	ectoderm formation	6.224474e-3
GO:0072560	type B pancreatic cell maturation	6.249596e-3
GO:0003283	atrial septum development	6.352118e-3
GO:0060466	activation of meiosis involved in egg activation	6.519997e-3
GO:0000738	DNA catabolic process, exonucleolytic	6.519997e-3
GO:0008053	mitochondrial fusion	6.519997e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	6.552426e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	6.562765e-3
GO:0006450	regulation of translational fidelity	6.628837e-3
GO:0043153	entrainment of circadian clock by photoperiod	6.628837e-3
GO:0051586	positive regulation of dopamine uptake	6.628837e-3
GO:0021930	cerebellar granule cell precursor proliferation	6.628837e-3
GO:0007052	mitotic spindle organization	6.664959e-3
GO:0090292	nuclear matrix anchoring at nuclear membrane	6.728961e-3
GO:0021539	subthalamus development	6.728961e-3
GO:0035269	protein O-linked mannosylation	6.728961e-3
GO:0032069	regulation of nuclease activity	6.853802e-3
GO:0014009	glial cell proliferation	6.918772e-3
GO:0007031	peroxisome organization	6.978581e-3
GO:0010721	negative regulation of cell development	7.008057e-3
GO:0045987	positive regulation of smooth muscle contraction	7.129864e-3
GO:0060486	Clara cell differentiation	7.150446e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	7.649421e-3
GO:0045906	negative regulation of vasoconstriction	7.649421e-3
GO:0016572	histone phosphorylation	7.658061e-3
GO:0002072	optic cup morphogenesis involved in camera-type eye development	7.841488e-3
GO:0060022	hard palate development	7.841488e-3
GO:0022037	metencephalon development	7.865428e-3
GO:0045792	negative regulation of cell size	7.936651e-3
GO:0034508	centromere complex assembly	7.936651e-3
GO:0006401	RNA catabolic process	7.958171e-3
GO:0032525	somite rostral/caudal axis specification	8.090832e-3
GO:0060972	left/right pattern formation	8.101137e-3
GO:0006303	double-strand break repair via nonhomologous end joining	8.101137e-3
GO:0072221	metanephric distal convoluted tubule development	8.138263e-3
GO:0061188	negative regulation of chromatin silencing at rDNA	8.317301e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	8.329119e-3
GO:0016558	protein import into peroxisome matrix	8.393194e-3
GO:0007098	centrosome cycle	8.402720e-3
GO:0097029	mature dendritic cell differentiation	8.407507e-3
GO:2000001	regulation of DNA damage checkpoint	8.407507e-3
GO:0070368	positive regulation of hepatocyte differentiation	8.407507e-3
GO:0003273	cell migration involved in endocardial cushion formation	8.407507e-3
GO:2000078	positive regulation of type B pancreatic cell development	9.115809e-3
GO:0009648	photoperiodism	9.115809e-3
GO:0009082	branched chain family amino acid biosynthetic process	9.361286e-3
GO:0008050	female courtship behavior	9.586317e-3
GO:0046479	glycosphingolipid catabolic process	9.586317e-3
GO:0090336	positive regulation of brown fat cell differentiation	9.612440e-3
GO:0090271	positive regulation of fibroblast growth factor production	9.612440e-3
GO:0090362	positive regulation of platelet-derived growth factor production	9.612440e-3
GO:0006154	adenosine catabolic process	9.612440e-3
GO:0046103	inosine biosynthetic process	9.612440e-3
GO:0032431	activation of phospholipase A2 activity	9.612440e-3
GO:0097028	dendritic cell differentiation	9.654662e-3
GO:0035520	monoubiquitinated protein deubiquitination	9.654662e-3
GO:0000209	protein polyubiquitination	9.726266e-3
GO:0031109	microtubule polymerization or depolymerization	1.018299e-2
GO:0021860	pyramidal neuron development	1.018299e-2
GO:0003285	septum secundum development	1.045713e-2
GO:0006651	diacylglycerol biosynthetic process	1.045713e-2
GO:0043538	regulation of actin phosphorylation	1.058226e-2
GO:0015969	guanosine tetraphosphate metabolic process	1.058226e-2
GO:0090212	negative regulation of establishment of blood-brain barrier	1.058226e-2
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	1.058226e-2
GO:0006666	3-keto-sphinganine metabolic process	1.058226e-2
GO:0009236	cobalamin biosynthetic process	1.058226e-2
GO:0061015	snRNA import into nucleus	1.076447e-2
GO:0035502	metanephric ureteric bud development	1.076447e-2
GO:0006683	galactosylceramide catabolic process	1.076447e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.076447e-2
GO:0017187	peptidyl-glutamic acid carboxylation	1.076447e-2
GO:0007059	chromosome segregation	1.112675e-2
GO:0032922	circadian regulation of gene expression	1.113881e-2
GO:0046827	positive regulation of protein export from nucleus	1.120537e-2
GO:0032774	RNA biosynthetic process	1.130317e-2
GO:0051313	attachment of spindle microtubules to chromosome	1.135221e-2
GO:0006390	transcription from mitochondrial promoter	1.135841e-2
GO:0048854	brain morphogenesis	1.139208e-2
GO:0003002	regionalization	1.146928e-2
GO:0072132	mesenchyme morphogenesis	1.184865e-2
GO:0070979	protein K11-linked ubiquitination	1.203878e-2
GO:0006269	DNA replication, synthesis of RNA primer	1.215815e-2
GO:0021568	rhombomere 2 development	1.215815e-2
GO:0001840	neural plate development	1.217394e-2
GO:0032202	telomere assembly	1.223636e-2
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.223636e-2
GO:0072044	collecting duct development	1.236207e-2
GO:0006105	succinate metabolic process	1.241539e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.246249e-2
GO:0048793	pronephros development	1.257080e-2
GO:0050768	negative regulation of neurogenesis	1.259519e-2
GO:0006351	transcription, DNA-dependent	1.275333e-2
GO:0032331	negative regulation of chondrocyte differentiation	1.291486e-2
GO:0031323	regulation of cellular metabolic process	1.295081e-2
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1.308627e-2
GO:0003323	type B pancreatic cell development	1.329520e-2
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	1.340913e-2
GO:0046092	deoxycytidine metabolic process	1.340913e-2
GO:0034498	early endosome to Golgi transport	1.340913e-2
GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	1.340913e-2
GO:0032608	interferon-beta production	1.340913e-2
GO:0072488	ammonium transmembrane transport	1.345582e-2
GO:0071585	detoxification of cadmium ion	1.359603e-2
GO:2000615	regulation of histone H3-K9 acetylation	1.359603e-2
GO:0071539	protein localization to centrosome	1.359603e-2
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	1.359603e-2
GO:0006807	nitrogen compound metabolic process	1.365627e-2
GO:0006264	mitochondrial DNA replication	1.367004e-2
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.404768e-2
GO:0003290	atrial septum secundum morphogenesis	1.404768e-2
GO:0070845	polyubiquitinated misfolded protein transport	1.408769e-2
GO:0061301	cerebellum vasculature morphogenesis	1.408769e-2
GO:2000778	positive regulation of interleukin-6 secretion	1.408769e-2
GO:0030421	defecation	1.408769e-2
GO:0032074	negative regulation of nuclease activity	1.408769e-2
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	1.408769e-2
GO:0071845	cellular component disassembly at cellular level	1.414816e-2
GO:0031018	endocrine pancreas development	1.450233e-2
GO:0060430	lung saccule development	1.457871e-2
GO:0001707	mesoderm formation	1.476123e-2
GO:0003272	endocardial cushion formation	1.519560e-2
GO:0090381	regulation of heart induction	1.523278e-2
GO:0090361	regulation of platelet-derived growth factor production	1.523278e-2
GO:0019673	GDP-mannose metabolic process	1.523278e-2
GO:0001832	blastocyst growth	1.553743e-2
GO:0033365	protein localization to organelle	1.556589e-2
GO:0000819	sister chromatid segregation	1.578983e-2
GO:0035434	copper ion transmembrane transport	1.588838e-2
GO:0032446	protein modification by small protein conjugation	1.589549e-2
GO:0072054	renal outer medulla development	1.593327e-2
GO:0046620	regulation of organ growth	1.606459e-2
GO:0070842	aggresome assembly	1.607403e-2
GO:0030422	production of siRNA involved in RNA interference	1.607403e-2
GO:0043985	histone H4-R3 methylation	1.607403e-2
GO:0042424	catecholamine catabolic process	1.626677e-2
GO:0061205	paramesonephric duct development	1.626677e-2
GO:0006116	NADH oxidation	1.626677e-2
GO:0055118	negative regulation of cardiac muscle contraction	1.632577e-2
GO:0050774	negative regulation of dendrite morphogenesis	1.632577e-2
GO:0051303	establishment of chromosome localization	1.652721e-2
GO:0051171	regulation of nitrogen compound metabolic process	1.652974e-2
GO:0071285	cellular response to lithium ion	1.654207e-2
GO:0034645	cellular macromolecule biosynthetic process	1.656345e-2
GO:0007093	mitotic cell cycle checkpoint	1.701626e-2
GO:0042119	neutrophil activation	1.724016e-2
GO:0070918	production of small RNA involved in gene silencing by RNA	1.744014e-2
GO:0021527	spinal cord association neuron differentiation	1.748014e-2
GO:0035054	embryonic heart tube anterior/posterior pattern specification	1.781353e-2
GO:0002065	columnar/cuboidal epithelial cell differentiation	1.781931e-2
GO:0072197	ureter morphogenesis	1.795030e-2
GO:0072076	nephrogenic mesenchyme development	1.810359e-2
GO:0043697	cell dedifferentiation	1.810359e-2
GO:0072177	mesonephric duct development	1.811331e-2
GO:0016180	snRNA processing	1.811331e-2
GO:0046784	intronless viral mRNA export from host nucleus	1.811331e-2
GO:0022411	cellular component disassembly	1.842529e-2
GO:0060433	bronchus development	1.846993e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.853047e-2
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.856553e-2
GO:0007051	spindle organization	1.863039e-2
GO:0032006	regulation of TOR signaling cascade	1.867098e-2
GO:0051542	elastin biosynthetic process	1.875899e-2
GO:2000256	positive regulation of male germ cell proliferation	1.875899e-2
GO:0045900	negative regulation of translational elongation	1.875899e-2
GO:0048553	negative regulation of metalloenzyme activity	1.875899e-2
GO:0006258	UDP-glucose catabolic process	1.875899e-2
GO:0006844	acyl carnitine transport	1.875899e-2
GO:0042231	interleukin-13 biosynthetic process	1.875899e-2
GO:0051204	protein insertion into mitochondrial membrane	1.884959e-2
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	1.884959e-2
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	1.884959e-2
GO:0006354	transcription elongation, DNA-dependent	1.899066e-2
GO:0000959	mitochondrial RNA metabolic process	1.901322e-2
GO:0071824	protein-DNA complex subunit organization	1.909575e-2
GO:0048384	retinoic acid receptor signaling pathway	1.914686e-2
GO:0030889	negative regulation of B cell proliferation	1.928064e-2
GO:0034501	protein localization to kinetochore	1.935518e-2
GO:0055119	relaxation of cardiac muscle	1.936462e-2
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	1.936462e-2
GO:0051865	protein autoubiquitination	1.944159e-2
GO:0072053	renal inner medulla development	1.949828e-2
GO:0035329	hippo signaling cascade	1.967124e-2
GO:0050684	regulation of mRNA processing	1.980600e-2
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.983062e-2
GO:0033084	regulation of immature T cell proliferation in thymus	1.985932e-2
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.985932e-2
GO:0001839	neural plate morphogenesis	1.985932e-2
GO:0007369	gastrulation	1.991789e-2
GO:0090184	positive regulation of kidney development	2.028450e-2
GO:0015812	gamma-aminobutyric acid transport	2.054356e-2
GO:0046602	regulation of mitotic centrosome separation	2.057131e-2
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.057131e-2
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.057131e-2
GO:0000917	barrier septum formation	2.057131e-2
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	2.070912e-2
GO:0043491	protein kinase B signaling cascade	2.078985e-2
GO:0051168	nuclear export	2.087004e-2
GO:0042796	snRNA transcription from RNA polymerase III promoter	2.088604e-2
GO:2000002	negative regulation of DNA damage checkpoint	2.088604e-2
GO:0042795	snRNA transcription from RNA polymerase II promoter	2.088604e-2
GO:0021588	cerebellum formation	2.088604e-2
GO:0022004	midbrain-hindbrain boundary maturation during brain development	2.088604e-2