Novel motif:12

name:	motif12_ACTAAG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002684	positive regulation of immune system process	1.133217e-13
GO:0006955	immune response	3.184646e-13
GO:0042221	response to chemical stimulus	6.230115e-12
GO:0050896	response to stimulus	1.027958e-11
GO:0006950	response to stress	1.216224e-11
GO:0016445	somatic diversification of immunoglobulins	1.458576e-11
GO:0033490	cholesterol biosynthetic process via lathosterol	3.349483e-10
GO:0002376	immune system process	4.755251e-10
GO:0019441	tryptophan catabolic process to kynurenine	9.588303e-10
GO:0042264	peptidyl-aspartic acid hydroxylation	9.969456e-10
GO:0002696	positive regulation of leukocyte activation	1.058966e-9
GO:0048584	positive regulation of response to stimulus	1.226843e-9
GO:0016447	somatic recombination of immunoglobulin gene segments	1.424997e-9
GO:0002694	regulation of leukocyte activation	1.570413e-9
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	1.752156e-9
GO:0002377	immunoglobulin production	4.019303e-9
GO:0002200	somatic diversification of immune receptors	4.037279e-9
GO:0050867	positive regulation of cell activation	6.408082e-9
GO:0021854	hypothalamus development	7.885149e-9
GO:0021778	oligodendrocyte cell fate specification	7.931515e-9
GO:0046579	positive regulation of Ras protein signal transduction	8.359413e-9
GO:0070189	kynurenine metabolic process	1.037738e-8
GO:0050864	regulation of B cell activation	1.179319e-8
GO:0051057	positive regulation of small GTPase mediated signal transduction	1.194101e-8
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.461272e-8
GO:0030185	nitric oxide transport	1.537389e-8
GO:0009072	aromatic amino acid family metabolic process	1.634751e-8
GO:0006568	tryptophan metabolic process	1.725925e-8
GO:0051249	regulation of lymphocyte activation	2.035463e-8
GO:0009593	detection of chemical stimulus	2.142400e-8
GO:0006569	tryptophan catabolic process	3.382132e-8
GO:0050865	regulation of cell activation	4.456045e-8
GO:0019439	aromatic compound catabolic process	5.738701e-8
GO:0048518	positive regulation of biological process	7.732565e-8
GO:0021781	glial cell fate commitment	1.026809e-7
GO:0035330	regulation of hippo signaling cascade	1.031102e-7
GO:0051592	response to calcium ion	1.081089e-7
GO:0010033	response to organic substance	1.144133e-7
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	1.169620e-7
GO:0010613	positive regulation of cardiac muscle hypertrophy	1.478289e-7
GO:0002819	regulation of adaptive immune response	1.482444e-7
GO:0006586	indolalkylamine metabolic process	1.687515e-7
GO:0051251	positive regulation of lymphocyte activation	1.768155e-7
GO:0009750	response to fructose stimulus	1.796393e-7
GO:0051918	negative regulation of fibrinolysis	1.836616e-7
GO:0006310	DNA recombination	2.070658e-7
GO:0009074	aromatic amino acid family catabolic process	2.306812e-7
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	2.331388e-7
GO:0002757	immune response-activating signal transduction	2.336791e-7
GO:0051917	regulation of fibrinolysis	2.343168e-7
GO:0002682	regulation of immune system process	2.591115e-7
GO:0001775	cell activation	2.723714e-7
GO:0060011	Sertoli cell proliferation	3.149002e-7
GO:0021779	oligodendrocyte cell fate commitment	3.523685e-7
GO:0015942	formate metabolic process	4.030015e-7
GO:0031349	positive regulation of defense response	4.845592e-7
GO:2000379	positive regulation of reactive oxygen species metabolic process	4.877943e-7
GO:0030335	positive regulation of cell migration	5.382825e-7
GO:0018126	protein hydroxylation	5.703830e-7
GO:0002329	pre-B cell differentiation	6.719576e-7
GO:0002666	positive regulation of T cell tolerance induction	7.000608e-7
GO:0010038	response to metal ion	7.309567e-7
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	7.698624e-7
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.765046e-7
GO:0002764	immune response-regulating signaling pathway	9.172438e-7
GO:0051096	positive regulation of helicase activity	9.598006e-7
GO:0009744	response to sucrose stimulus	1.042312e-6
GO:0080134	regulation of response to stress	1.065135e-6
GO:2000147	positive regulation of cell motility	1.101250e-6
GO:0008045	motor axon guidance	1.101625e-6
GO:0002690	positive regulation of leukocyte chemotaxis	1.125693e-6
GO:0032891	negative regulation of organic acid transport	1.160912e-6
GO:0051716	cellular response to stimulus	1.522198e-6
GO:0051179	localization	1.631311e-6
GO:0000710	meiotic mismatch repair	1.658361e-6
GO:0002440	production of molecular mediator of immune response	1.766191e-6
GO:0002285	lymphocyte activation involved in immune response	1.880464e-6
GO:0032890	regulation of organic acid transport	2.070195e-6
GO:0051272	positive regulation of cellular component movement	2.158287e-6
GO:0032103	positive regulation of response to external stimulus	2.708775e-6
GO:0030888	regulation of B cell proliferation	3.017237e-6
GO:0002688	regulation of leukocyte chemotaxis	3.228079e-6
GO:0090208	positive regulation of triglyceride metabolic process	3.271931e-6
GO:0032927	positive regulation of activin receptor signaling pathway	3.273628e-6
GO:0048520	positive regulation of behavior	3.459102e-6
GO:0043502	regulation of muscle adaptation	3.535349e-6
GO:0019722	calcium-mediated signaling	3.665944e-6
GO:0045321	leukocyte activation	3.696216e-6
GO:0043420	anthranilate metabolic process	3.778345e-6
GO:0034516	response to vitamin B6	3.778345e-6
GO:0051095	regulation of helicase activity	3.893125e-6
GO:0032472	Golgi calcium ion transport	3.993506e-6
GO:0032468	Golgi calcium ion homeostasis	3.993506e-6
GO:0030026	cellular manganese ion homeostasis	3.993506e-6
GO:0048522	positive regulation of cellular process	4.070765e-6
GO:0046634	regulation of alpha-beta T cell activation	4.159481e-6
GO:0040017	positive regulation of locomotion	4.533827e-6
GO:0002700	regulation of production of molecular mediator of immune response	4.901363e-6
GO:0017038	protein import	5.072132e-6
GO:0051895	negative regulation of focal adhesion assembly	5.209614e-6
GO:0002687	positive regulation of leukocyte migration	5.387274e-6
GO:0045429	positive regulation of nitric oxide biosynthetic process	5.634294e-6
GO:0007131	reciprocal meiotic recombination	5.659233e-6
GO:0050818	regulation of coagulation	5.860191e-6
GO:0070663	regulation of leukocyte proliferation	6.083708e-6
GO:0010955	negative regulation of protein processing	6.156721e-6
GO:0010611	regulation of cardiac muscle hypertrophy	6.820874e-6
GO:0006810	transport	7.171658e-6
GO:0006427	histidyl-tRNA aminoacylation	7.397300e-6
GO:0030183	B cell differentiation	7.910438e-6
GO:0051234	establishment of localization	8.131914e-6
GO:0001819	positive regulation of cytokine production	8.513593e-6
GO:0051481	reduction of cytosolic calcium ion concentration	8.907782e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	9.235427e-6
GO:0034605	cellular response to heat	9.328882e-6
GO:0006952	defense response	9.857633e-6
GO:0050776	regulation of immune response	9.985844e-6
GO:0007320	insemination	1.107000e-5
GO:0009611	response to wounding	1.124079e-5
GO:0002645	positive regulation of tolerance induction	1.206608e-5
GO:0033147	negative regulation of estrogen receptor signaling pathway	1.236757e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.248433e-5
GO:0050871	positive regulation of B cell activation	1.283916e-5
GO:0051188	cofactor biosynthetic process	1.299676e-5
GO:2000191	regulation of fatty acid transport	1.301807e-5
GO:0021536	diencephalon development	1.344892e-5
GO:0002637	regulation of immunoglobulin production	1.357247e-5
GO:0007154	cell communication	1.359650e-5
GO:0023052	signaling	1.384403e-5
GO:0018874	benzoate metabolic process	1.404763e-5
GO:0006906	vesicle fusion	1.421027e-5
GO:0042127	regulation of cell proliferation	1.523335e-5
GO:0045428	regulation of nitric oxide biosynthetic process	1.754483e-5
GO:0032655	regulation of interleukin-12 production	1.754483e-5
GO:0050778	positive regulation of immune response	1.794699e-5
GO:0014743	regulation of muscle hypertrophy	1.798927e-5
GO:0002706	regulation of lymphocyte mediated immunity	1.840805e-5
GO:0016525	negative regulation of angiogenesis	1.861363e-5
GO:0046475	glycerophospholipid catabolic process	2.075597e-5
GO:0032924	activin receptor signaling pathway	2.078868e-5
GO:0002699	positive regulation of immune effector process	2.104814e-5
GO:0009756	carbohydrate mediated signaling	2.138534e-5
GO:0005513	detection of calcium ion	2.338272e-5
GO:0033152	immunoglobulin V(D)J recombination	2.381954e-5
GO:0061041	regulation of wound healing	2.397899e-5
GO:0048284	organelle fusion	2.555219e-5
GO:0009449	gamma-aminobutyric acid biosynthetic process	2.578408e-5
GO:0010941	regulation of cell death	2.756758e-5
GO:0048583	regulation of response to stimulus	2.773685e-5
GO:0002253	activation of immune response	2.786965e-5
GO:0032680	regulation of tumor necrosis factor production	2.980334e-5
GO:0050820	positive regulation of coagulation	2.994705e-5
GO:0007165	signal transduction	3.050258e-5
GO:2001108	positive regulation of Rho guanyl-nucleotide exchange factor activity	3.085636e-5
GO:0019674	NAD metabolic process	3.209957e-5
GO:0010754	negative regulation of cGMP-mediated signaling	3.217172e-5
GO:0043652	engulfment of apoptotic cell	3.217172e-5
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	3.217172e-5
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.217172e-5
GO:0010751	negative regulation of nitric oxide mediated signal transduction	3.217172e-5
GO:0050921	positive regulation of chemotaxis	3.233286e-5
GO:0043067	regulation of programmed cell death	3.263181e-5
GO:0006605	protein targeting	3.294361e-5
GO:0002218	activation of innate immune response	3.311323e-5
GO:0009743	response to carbohydrate stimulus	3.374521e-5
GO:0042981	regulation of apoptosis	3.534644e-5
GO:0021761	limbic system development	3.648275e-5
GO:0006936	muscle contraction	3.690229e-5
GO:0055067	monovalent inorganic cation homeostasis	3.832739e-5
GO:0006447	regulation of translational initiation by iron	3.939479e-5
GO:0002685	regulation of leukocyte migration	4.029079e-5
GO:0032729	positive regulation of interferon-gamma production	4.056105e-5
GO:0021530	spinal cord oligodendrocyte cell fate specification	4.144354e-5
GO:0008625	induction of apoptosis via death domain receptors	4.175883e-5
GO:0030520	estrogen receptor signaling pathway	4.183032e-5
GO:0042060	wound healing	4.864324e-5
GO:0010867	positive regulation of triglyceride biosynthetic process	4.953875e-5
GO:0050907	detection of chemical stimulus involved in sensory perception	4.967614e-5
GO:0018149	peptide cross-linking	5.119165e-5
GO:0045089	positive regulation of innate immune response	5.357347e-5
GO:0007620	copulation	5.944478e-5
GO:0032695	negative regulation of interleukin-12 production	5.998815e-5
GO:0002697	regulation of immune effector process	6.081268e-5
GO:0052547	regulation of peptidase activity	6.108700e-5
GO:0043030	regulation of macrophage activation	6.204848e-5
GO:0045994	positive regulation of translational initiation by iron	6.324834e-5
GO:0002037	negative regulation of L-glutamate transport	6.324834e-5
GO:0033365	protein localization to organelle	6.789010e-5
GO:0030193	regulation of blood coagulation	6.890067e-5
GO:0033025	regulation of mast cell apoptosis	6.898106e-5
GO:0002429	immune response-activating cell surface receptor signaling pathway	7.256325e-5
GO:0009893	positive regulation of metabolic process	7.474796e-5
GO:0046874	quinolinate metabolic process	7.639307e-5
GO:0006885	regulation of pH	7.743915e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	7.760591e-5
GO:0050819	negative regulation of coagulation	7.817375e-5
GO:0030890	positive regulation of B cell proliferation	7.950256e-5
GO:0045087	innate immune response	8.052137e-5
GO:0030194	positive regulation of blood coagulation	8.623785e-5
GO:0009653	anatomical structure morphogenesis	8.759869e-5
GO:0010647	positive regulation of cell communication	8.948919e-5
GO:0009967	positive regulation of signal transduction	9.347707e-5
GO:0021979	hypothalamus cell differentiation	9.410720e-5
GO:0010035	response to inorganic substance	9.522002e-5
GO:0060324	face development	9.730025e-5
GO:0050670	regulation of lymphocyte proliferation	9.867061e-5
GO:0023056	positive regulation of signaling	1.009766e-4
GO:0032287	peripheral nervous system myelin maintenance	1.018565e-4
GO:0006001	fructose catabolic process	1.018565e-4
GO:0051597	response to methylmercury	1.037114e-4
GO:0015871	choline transport	1.039328e-4
GO:0070665	positive regulation of leukocyte proliferation	1.056340e-4
GO:0033032	regulation of myeloid cell apoptosis	1.065117e-4
GO:0001932	regulation of protein phosphorylation	1.116856e-4
GO:0032369	negative regulation of lipid transport	1.150245e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.164630e-4
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.199039e-4
GO:0045091	regulation of retroviral genome replication	1.205839e-4
GO:0051023	regulation of immunoglobulin secretion	1.222392e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	1.225413e-4
GO:0032944	regulation of mononuclear cell proliferation	1.230576e-4
GO:0042404	thyroid hormone catabolic process	1.233077e-4
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	1.250700e-4
GO:0044036	cell wall macromolecule metabolic process	1.299983e-4
GO:0006828	manganese ion transport	1.320427e-4
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	1.333948e-4
GO:0002678	positive regulation of chronic inflammatory response	1.376997e-4
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	1.377138e-4
GO:0021985	neurohypophysis development	1.389297e-4
GO:0032879	regulation of localization	1.394341e-4
GO:0042325	regulation of phosphorylation	1.394469e-4
GO:0010942	positive regulation of cell death	1.404161e-4
GO:0009395	phospholipid catabolic process	1.412589e-4
GO:0002639	positive regulation of immunoglobulin production	1.438046e-4
GO:0050870	positive regulation of T cell activation	1.445528e-4
GO:0043069	negative regulation of programmed cell death	1.469683e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.500828e-4
GO:0002920	regulation of humoral immune response	1.547027e-4
GO:0043066	negative regulation of apoptosis	1.557043e-4
GO:0050853	B cell receptor signaling pathway	1.576736e-4
GO:0022402	cell cycle process	1.596696e-4
GO:0007588	excretion	1.596785e-4
GO:0045190	isotype switching	1.598679e-4
GO:0042402	cellular biogenic amine catabolic process	1.603988e-4
GO:0002651	positive regulation of tolerance induction to self antigen	1.661798e-4
GO:0021983	pituitary gland development	1.666227e-4
GO:0070723	response to cholesterol	1.667473e-4
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.712637e-4
GO:0046642	negative regulation of alpha-beta T cell proliferation	1.728925e-4
GO:0016339	calcium-dependent cell-cell adhesion	1.729119e-4
GO:0016126	sterol biosynthetic process	1.776446e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.865795e-4
GO:0010660	regulation of muscle cell apoptosis	1.878801e-4
GO:0000416	positive regulation of histone H3-K36 methylation	1.879500e-4
GO:0035634	response to stilbenoid	1.887910e-4
GO:0032317	regulation of Rap GTPase activity	1.928355e-4
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.930255e-4
GO:0070482	response to oxygen levels	1.935238e-4
GO:0008284	positive regulation of cell proliferation	1.946492e-4
GO:0034097	response to cytokine stimulus	1.984809e-4
GO:0015031	protein transport	1.990189e-4
GO:0007258	JUN phosphorylation	2.018397e-4
GO:0009306	protein secretion	2.051989e-4
GO:0002286	T cell activation involved in immune response	2.059261e-4
GO:0002669	positive regulation of T cell anergy	2.075149e-4
GO:0019220	regulation of phosphate metabolic process	2.078627e-4
GO:0042493	response to drug	2.095095e-4
GO:0016446	somatic hypermutation of immunoglobulin genes	2.103964e-4
GO:0006968	cellular defense response	2.156654e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	2.262011e-4
GO:0010039	response to iron ion	2.262223e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	2.286542e-4
GO:0046649	lymphocyte activation	2.297309e-4
GO:0002312	B cell activation involved in immune response	2.328460e-4
GO:0090074	negative regulation of protein homodimerization activity	2.331882e-4
GO:0071673	positive regulation of smooth muscle cell chemotaxis	2.331882e-4
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	2.377819e-4
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	2.384098e-4
GO:0034139	regulation of toll-like receptor 3 signaling pathway	2.400891e-4
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	2.469300e-4
GO:0051707	response to other organism	2.495984e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2.589399e-4
GO:0051704	multi-organism process	2.593593e-4
GO:0033033	negative regulation of myeloid cell apoptosis	2.595626e-4
GO:0002520	immune system development	2.626326e-4
GO:0051186	cofactor metabolic process	2.725293e-4
GO:0014075	response to amine stimulus	2.748522e-4
GO:0007618	mating	2.772258e-4
GO:0071622	regulation of granulocyte chemotaxis	2.778242e-4
GO:0042113	B cell activation	2.844819e-4
GO:0071840	cellular component organization or biogenesis	2.865221e-4
GO:0007006	mitochondrial membrane organization	2.885366e-4
GO:0050851	antigen receptor-mediated signaling pathway	2.929594e-4
GO:0002683	negative regulation of immune system process	2.950966e-4
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	2.964895e-4
GO:0033554	cellular response to stress	2.982642e-4
GO:0002821	positive regulation of adaptive immune response	3.024529e-4
GO:0035051	cardiac cell differentiation	3.035473e-4
GO:0043068	positive regulation of programmed cell death	3.040594e-4
GO:0043032	positive regulation of macrophage activation	3.061895e-4
GO:0042663	regulation of endodermal cell fate specification	3.086135e-4
GO:0006769	nicotinamide metabolic process	3.142208e-4
GO:0042953	lipoprotein transport	3.154328e-4
GO:0050973	detection of mechanical stimulus involved in equilibrioception	3.244111e-4
GO:0030210	heparin biosynthetic process	3.296458e-4
GO:0043490	malate-aspartate shuttle	3.297819e-4
GO:0045767	regulation of anti-apoptosis	3.297962e-4
GO:0010996	response to auditory stimulus	3.306433e-4
GO:0050795	regulation of behavior	3.311760e-4
GO:0070887	cellular response to chemical stimulus	3.356919e-4
GO:0009607	response to biotic stimulus	3.399541e-4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3.434260e-4
GO:0050663	cytokine secretion	3.466636e-4
GO:0009408	response to heat	3.480633e-4
GO:0048743	positive regulation of skeletal muscle fiber development	3.502694e-4
GO:0010212	response to ionizing radiation	3.504267e-4
GO:0035261	external genitalia morphogenesis	3.506914e-4
GO:0045088	regulation of innate immune response	3.561608e-4
GO:0001817	regulation of cytokine production	3.595377e-4
GO:0032514	positive regulation of protein phosphatase type 2B activity	3.596649e-4
GO:0060434	bronchus morphogenesis	3.596649e-4
GO:0015671	oxygen transport	3.718642e-4
GO:0060548	negative regulation of cell death	3.723917e-4
GO:0009056	catabolic process	3.769321e-4
GO:0006311	meiotic gene conversion	3.893597e-4
GO:0045128	negative regulation of reciprocal meiotic recombination	3.893597e-4
GO:0002712	regulation of B cell mediated immunity	3.950706e-4
GO:0008152	metabolic process	3.980936e-4
GO:0003012	muscle system process	4.024373e-4
GO:2000278	regulation of DNA biosynthetic process	4.046425e-4
GO:0030388	fructose 1,6-bisphosphate metabolic process	4.053316e-4
GO:0072334	UDP-galactose transmembrane transport	4.080490e-4
GO:0045910	negative regulation of DNA recombination	4.092797e-4
GO:0021952	central nervous system projection neuron axonogenesis	4.152755e-4
GO:0009891	positive regulation of biosynthetic process	4.178906e-4
GO:0060325	face morphogenesis	4.179218e-4
GO:0008340	determination of adult lifespan	4.256107e-4
GO:0010757	negative regulation of plasminogen activation	4.265119e-4
GO:0032501	multicellular organismal process	4.276476e-4
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	4.305721e-4
GO:0042554	superoxide anion generation	4.362951e-4
GO:0040011	locomotion	4.368902e-4
GO:0045184	establishment of protein localization	4.494761e-4
GO:0042832	defense response to protozoan	4.640717e-4
GO:0032368	regulation of lipid transport	4.697044e-4
GO:0019255	glucose 1-phosphate metabolic process	4.726518e-4
GO:0034383	low-density lipoprotein particle clearance	4.761645e-4
GO:0046328	regulation of JNK cascade	4.878069e-4
GO:0043269	regulation of ion transport	4.910728e-4
GO:0012501	programmed cell death	4.937108e-4
GO:0006911	phagocytosis, engulfment	4.996047e-4
GO:0071674	mononuclear cell migration	5.019256e-4
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	5.019256e-4
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	5.072030e-4
GO:0050920	regulation of chemotaxis	5.074178e-4
GO:0060706	cell differentiation involved in embryonic placenta development	5.075761e-4
GO:0030004	cellular monovalent inorganic cation homeostasis	5.143154e-4
GO:0002673	regulation of acute inflammatory response	5.224239e-4
GO:0031347	regulation of defense response	5.301672e-4
GO:0043065	positive regulation of apoptosis	5.329926e-4
GO:0043049	otic placode formation	5.395309e-4
GO:0019805	quinolinate biosynthetic process	5.395309e-4
GO:0060322	head development	5.454256e-4
GO:0006779	porphyrin-containing compound biosynthetic process	5.558414e-4
GO:0051409	response to nitrosative stress	5.636413e-4
GO:0010759	positive regulation of macrophage chemotaxis	5.844430e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	5.864222e-4
GO:0046677	response to antibiotic	5.881430e-4
GO:0001953	negative regulation of cell-matrix adhesion	6.015522e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.047693e-4
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	6.103563e-4
GO:0050671	positive regulation of lymphocyte proliferation	6.109471e-4
GO:0016998	cell wall macromolecule catabolic process	6.114757e-4
GO:0010595	positive regulation of endothelial cell migration	6.120256e-4
GO:0030522	intracellular receptor mediated signaling pathway	6.209273e-4
GO:0009249	protein lipoylation	6.319749e-4
GO:0043084	penile erection	6.319749e-4
GO:0032101	regulation of response to external stimulus	6.347150e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	6.381959e-4
GO:0009605	response to external stimulus	6.557139e-4
GO:0009266	response to temperature stimulus	6.621804e-4
GO:0035444	nickel ion transmembrane transport	6.654200e-4
GO:0070627	ferrous iron import	6.654200e-4
GO:0015676	vanadium ion transport	6.654200e-4
GO:0015692	lead ion transport	6.654200e-4
GO:0007100	mitotic centrosome separation	6.654200e-4
GO:0002889	regulation of immunoglobulin mediated immune response	6.726644e-4
GO:0035025	positive regulation of Rho protein signal transduction	6.740078e-4
GO:0045622	regulation of T-helper cell differentiation	7.044878e-4
GO:0043200	response to amino acid stimulus	7.108535e-4
GO:0006812	cation transport	7.158053e-4
GO:0009084	glutamine family amino acid biosynthetic process	7.180471e-4
GO:0030202	heparin metabolic process	7.220637e-4
GO:0090116	C-5 methylation of cytosine	7.299959e-4
GO:0010259	multicellular organismal aging	7.381227e-4
GO:0002274	myeloid leukocyte activation	7.679672e-4
GO:0032946	positive regulation of mononuclear cell proliferation	7.691796e-4
GO:0002676	regulation of chronic inflammatory response	7.729810e-4
GO:0009820	alkaloid metabolic process	7.863326e-4
GO:0006805	xenobiotic metabolic process	7.915340e-4
GO:0060323	head morphogenesis	7.944026e-4
GO:0071675	regulation of mononuclear cell migration	7.947372e-4
GO:0070104	negative regulation of interleukin-6-mediated signaling pathway	7.968976e-4
GO:0060065	uterus development	8.116832e-4
GO:0044270	cellular nitrogen compound catabolic process	8.135352e-4
GO:0019751	polyol metabolic process	8.140945e-4
GO:0006606	protein import into nucleus	8.287258e-4
GO:0006298	mismatch repair	8.306698e-4
GO:0001773	myeloid dendritic cell activation	8.313997e-4
GO:0001101	response to acid	8.336997e-4
GO:0014041	regulation of neuron maturation	8.393932e-4
GO:0002036	regulation of L-glutamate transport	8.410250e-4
GO:0022612	gland morphogenesis	8.496615e-4
GO:0001562	response to protozoan	8.761755e-4
GO:0021957	corticospinal tract morphogenesis	8.870552e-4
GO:0033013	tetrapyrrole metabolic process	8.906982e-4
GO:0050863	regulation of T cell activation	8.926559e-4
GO:0051170	nuclear import	9.006753e-4
GO:0045916	negative regulation of complement activation	9.027760e-4
GO:0030195	negative regulation of blood coagulation	9.072960e-4
GO:0030001	metal ion transport	9.098242e-4
GO:0010627	regulation of intracellular protein kinase cascade	9.131388e-4
GO:0006915	apoptosis	9.296445e-4
GO:0050860	negative regulation of T cell receptor signaling pathway	9.327307e-4
GO:0071805	potassium ion transmembrane transport	9.369477e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	9.390020e-4
GO:0045768	positive regulation of anti-apoptosis	9.492904e-4
GO:0051956	negative regulation of amino acid transport	9.524134e-4
GO:0051893	regulation of focal adhesion assembly	9.534118e-4
GO:0010758	regulation of macrophage chemotaxis	9.576420e-4
GO:0071636	positive regulation of transforming growth factor beta production	9.660549e-4
GO:2000611	positive regulation of thyroid hormone generation	9.773719e-4
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	9.831978e-4
GO:0052548	regulation of endopeptidase activity	9.849024e-4
GO:0014842	regulation of satellite cell proliferation	1.008168e-3
GO:0046902	regulation of mitochondrial membrane permeability	1.023897e-3
GO:0010884	positive regulation of lipid storage	1.029930e-3
GO:0048014	Tie receptor signaling pathway	1.031350e-3
GO:0030334	regulation of cell migration	1.035108e-3
GO:0042327	positive regulation of phosphorylation	1.051909e-3
GO:0046640	regulation of alpha-beta T cell proliferation	1.055513e-3
GO:0032653	regulation of interleukin-10 production	1.059526e-3
GO:0046949	fatty-acyl-CoA biosynthetic process	1.067204e-3
GO:0010466	negative regulation of peptidase activity	1.080743e-3
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	1.083887e-3
GO:0033026	negative regulation of mast cell apoptosis	1.096561e-3
GO:0045937	positive regulation of phosphate metabolic process	1.098270e-3
GO:0032760	positive regulation of tumor necrosis factor production	1.098784e-3
GO:0007050	cell cycle arrest	1.101537e-3
GO:0046635	positive regulation of alpha-beta T cell activation	1.112982e-3
GO:0006694	steroid biosynthetic process	1.115996e-3
GO:0051896	regulation of protein kinase B signaling cascade	1.116511e-3
GO:0006695	cholesterol biosynthetic process	1.121850e-3
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	1.136296e-3
GO:2000612	regulation of thyroid-stimulating hormone secretion	1.139256e-3
GO:0007528	neuromuscular junction development	1.159970e-3
GO:0016043	cellular component organization	1.167702e-3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	1.189191e-3
GO:0006071	glycerol metabolic process	1.193771e-3
GO:0010812	negative regulation of cell-substrate adhesion	1.234540e-3
GO:0070184	mitochondrial tyrosyl-tRNA aminoacylation	1.241630e-3
GO:0046618	drug export	1.241630e-3
GO:0006778	porphyrin-containing compound metabolic process	1.245384e-3
GO:0002758	innate immune response-activating signal transduction	1.250803e-3
GO:0046637	regulation of alpha-beta T cell differentiation	1.252014e-3
GO:0042713	sperm ejaculation	1.259831e-3
GO:0009108	coenzyme biosynthetic process	1.266851e-3
GO:0010755	regulation of plasminogen activation	1.267765e-3
GO:0034765	regulation of ion transmembrane transport	1.269024e-3
GO:0060749	mammary gland alveolus development	1.276034e-3
GO:0031325	positive regulation of cellular metabolic process	1.280199e-3
GO:0002366	leukocyte activation involved in immune response	1.281397e-3
GO:0009628	response to abiotic stimulus	1.286808e-3
GO:0034638	phosphatidylcholine catabolic process	1.288389e-3
GO:0042742	defense response to bacterium	1.296948e-3
GO:0006213	pyrimidine nucleoside metabolic process	1.300051e-3
GO:0033993	response to lipid	1.320660e-3
GO:0030097	hemopoiesis	1.321566e-3
GO:0001504	neurotransmitter uptake	1.354030e-3
GO:2000351	regulation of endothelial cell apoptosis	1.355342e-3
GO:0055080	cation homeostasis	1.390173e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	1.395153e-3
GO:0031328	positive regulation of cellular biosynthetic process	1.405930e-3
GO:0043523	regulation of neuron apoptosis	1.409816e-3
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.419477e-3
GO:0071671	regulation of smooth muscle cell chemotaxis	1.422937e-3
GO:0007049	cell cycle	1.450727e-3
GO:0009409	response to cold	1.451178e-3
GO:0044281	small molecule metabolic process	1.459207e-3
GO:0010885	regulation of cholesterol storage	1.460954e-3
GO:0034465	response to carbon monoxide	1.461423e-3
GO:0019363	pyridine nucleotide biosynthetic process	1.485419e-3
GO:0006576	cellular biogenic amine metabolic process	1.486654e-3
GO:0031341	regulation of cell killing	1.517933e-3
GO:0071466	cellular response to xenobiotic stimulus	1.518548e-3
GO:0042730	fibrinolysis	1.535831e-3
GO:0043507	positive regulation of JUN kinase activity	1.547166e-3
GO:0046503	glycerolipid catabolic process	1.547680e-3
GO:0003014	renal system process	1.554153e-3
GO:0009617	response to bacterium	1.579915e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0018924	mandelate metabolic process	2.238957e-9
GO:0030149	sphingolipid catabolic process	5.957046e-8
GO:0070208	protein heterotrimerization	2.045621e-7
GO:0046466	membrane lipid catabolic process	2.177126e-7
GO:0006629	lipid metabolic process	3.100591e-7
GO:0060968	regulation of gene silencing	5.009615e-7
GO:0042448	progesterone metabolic process	6.821881e-7
GO:0007258	JUN phosphorylation	8.865862e-7
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.195771e-6
GO:0043589	skin morphogenesis	1.910683e-6
GO:0010519	negative regulation of phospholipase activity	2.262682e-6
GO:0044255	cellular lipid metabolic process	3.604567e-6
GO:0046514	ceramide catabolic process	4.052439e-6
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	4.290182e-6
GO:0001960	negative regulation of cytokine-mediated signaling pathway	5.724135e-6
GO:0010738	regulation of protein kinase A signaling cascade	5.919354e-6
GO:0042158	lipoprotein biosynthetic process	6.033278e-6
GO:0070206	protein trimerization	6.314882e-6
GO:0043200	response to amino acid stimulus	6.581680e-6
GO:0050896	response to stimulus	7.318959e-6
GO:0045585	positive regulation of cytotoxic T cell differentiation	7.496540e-6
GO:0034441	plasma lipoprotein particle oxidation	7.662967e-6
GO:0002021	response to dietary excess	9.158217e-6
GO:0030203	glycosaminoglycan metabolic process	9.888857e-6
GO:0071417	cellular response to organic nitrogen	1.154563e-5
GO:0006790	sulfur compound metabolic process	1.239067e-5
GO:0090074	negative regulation of protein homodimerization activity	1.319089e-5
GO:0071229	cellular response to acid	1.348911e-5
GO:0046640	regulation of alpha-beta T cell proliferation	1.391207e-5
GO:0005976	polysaccharide metabolic process	1.509893e-5
GO:0071418	cellular response to amine stimulus	1.671148e-5
GO:0007204	elevation of cytosolic calcium ion concentration	1.747866e-5
GO:0048239	negative regulation of DNA recombination at telomere	1.784179e-5
GO:0006430	lysyl-tRNA aminoacylation	1.784179e-5
GO:0030198	extracellular matrix organization	1.874742e-5
GO:0033865	nucleoside bisphosphate metabolic process	1.889872e-5
GO:0001957	intramembranous ossification	1.889872e-5
GO:0071872	cellular response to epinephrine stimulus	2.187354e-5
GO:0090026	positive regulation of monocyte chemotaxis	2.397018e-5
GO:0001959	regulation of cytokine-mediated signaling pathway	2.766531e-5
GO:0034374	low-density lipoprotein particle remodeling	2.863429e-5
GO:0071548	response to dexamethasone stimulus	3.059916e-5
GO:0071230	cellular response to amino acid stimulus	3.139812e-5
GO:2000507	positive regulation of energy homeostasis	3.900858e-5
GO:2000253	positive regulation of feeding behavior	3.900858e-5
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4.029987e-5
GO:0034114	regulation of heterotypic cell-cell adhesion	4.029987e-5
GO:0046642	negative regulation of alpha-beta T cell proliferation	4.051652e-5
GO:0050855	regulation of B cell receptor signaling pathway	4.150909e-5
GO:0042159	lipoprotein catabolic process	4.150909e-5
GO:0060759	regulation of response to cytokine stimulus	4.306816e-5
GO:0051414	response to cortisol stimulus	5.004685e-5
GO:0010743	regulation of macrophage derived foam cell differentiation	5.110491e-5
GO:0035229	positive regulation of glutamate-cysteine ligase activity	5.305968e-5
GO:0006968	cellular defense response	5.432456e-5
GO:0034612	response to tumor necrosis factor	5.505905e-5
GO:0001101	response to acid	5.506279e-5
GO:0065008	regulation of biological quality	5.564805e-5
GO:0042747	circadian sleep/wake cycle, REM sleep	5.691976e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	5.974915e-5
GO:0071379	cellular response to prostaglandin stimulus	6.264428e-5
GO:0006022	aminoglycan metabolic process	6.398034e-5
GO:2000505	regulation of energy homeostasis	6.849294e-5
GO:0051480	cytosolic calcium ion homeostasis	6.915387e-5
GO:0046479	glycosphingolipid catabolic process	7.245064e-5
GO:0009409	response to cold	7.694063e-5
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	7.758273e-5
GO:0002703	regulation of leukocyte mediated immunity	8.137873e-5
GO:0006661	phosphatidylinositol biosynthetic process	8.332277e-5
GO:0044272	sulfur compound biosynthetic process	8.343151e-5
GO:0046341	CDP-diacylglycerol metabolic process	9.055735e-5
GO:0043519	regulation of myosin II filament organization	9.171449e-5
GO:0032964	collagen biosynthetic process	9.648882e-5
GO:0071549	cellular response to dexamethasone stimulus	9.883976e-5
GO:0051291	protein heterooligomerization	1.044728e-4
GO:0002698	negative regulation of immune effector process	1.130986e-4
GO:0055013	cardiac muscle cell development	1.132241e-4
GO:0008202	steroid metabolic process	1.188059e-4
GO:0022410	circadian sleep/wake cycle process	1.214160e-4
GO:0051028	mRNA transport	1.229294e-4
GO:0051953	negative regulation of amine transport	1.409025e-4
GO:0051883	killing of cells in other organism involved in symbiotic interaction	1.444377e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	1.451662e-4
GO:0072249	metanephric glomerular visceral epithelial cell development	1.589315e-4
GO:0072274	metanephric glomerular basement membrane development	1.589315e-4
GO:0006683	galactosylceramide catabolic process	1.589315e-4
GO:0051932	synaptic transmission, GABAergic	1.589315e-4
GO:0048677	axon extension involved in regeneration	1.589315e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	1.589315e-4
GO:0030317	sperm motility	1.620442e-4
GO:0051259	protein oligomerization	1.627237e-4
GO:0031640	killing of cells of other organism	1.663076e-4
GO:0042157	lipoprotein metabolic process	1.713841e-4
GO:0009116	nucleoside metabolic process	1.768851e-4
GO:0006684	sphingomyelin metabolic process	1.783079e-4
GO:0050790	regulation of catalytic activity	1.826255e-4
GO:0071356	cellular response to tumor necrosis factor	1.897290e-4
GO:0001958	endochondral ossification	1.919266e-4
GO:0042953	lipoprotein transport	2.008783e-4
GO:0043547	positive regulation of GTPase activity	2.083825e-4
GO:0009266	response to temperature stimulus	2.100670e-4
GO:0030199	collagen fibril organization	2.185024e-4
GO:0009607	response to biotic stimulus	2.189306e-4
GO:0015936	coenzyme A metabolic process	2.359727e-4
GO:0042745	circadian sleep/wake cycle	2.372151e-4
GO:0009161	ribonucleoside monophosphate metabolic process	2.422309e-4
GO:0008610	lipid biosynthetic process	2.443812e-4
GO:0032321	positive regulation of Rho GTPase activity	2.479797e-4
GO:0050777	negative regulation of immune response	2.681428e-4
GO:0006642	triglyceride mobilization	2.701951e-4
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	2.717784e-4
GO:0051956	negative regulation of amino acid transport	2.846358e-4
GO:0055080	cation homeostasis	2.869079e-4
GO:0031342	negative regulation of cell killing	2.999796e-4
GO:0051641	cellular localization	3.004264e-4
GO:0015966	diadenosine tetraphosphate biosynthetic process	3.079517e-4
GO:0006672	ceramide metabolic process	3.080301e-4
GO:0071260	cellular response to mechanical stimulus	3.153709e-4
GO:0045670	regulation of osteoclast differentiation	3.198654e-4
GO:0002922	positive regulation of humoral immune response	3.228467e-4
GO:0006750	glutathione biosynthetic process	3.263032e-4
GO:0019368	fatty acid elongation, unsaturated fatty acid	3.278232e-4
GO:0050869	negative regulation of B cell activation	3.282089e-4
GO:0034113	heterotypic cell-cell adhesion	3.285446e-4
GO:0006885	regulation of pH	3.312477e-4
GO:0006749	glutathione metabolic process	3.327923e-4
GO:0002903	negative regulation of B cell apoptosis	3.380289e-4
GO:0032025	response to cobalt ion	3.583905e-4
GO:0045577	regulation of B cell differentiation	3.597486e-4
GO:0055006	cardiac cell development	3.740995e-4
GO:0006665	sphingolipid metabolic process	4.032016e-4
GO:0006643	membrane lipid metabolic process	4.134199e-4
GO:0030540	female genitalia development	4.303630e-4
GO:0009123	nucleoside monophosphate metabolic process	4.309840e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	4.332564e-4
GO:0072202	cell differentiation involved in metanephros development	4.496451e-4
GO:0050951	sensory perception of temperature stimulus	4.639500e-4
GO:0006518	peptide metabolic process	4.652864e-4
GO:0061002	negative regulation of dendritic spine morphogenesis	4.809523e-4
GO:0002820	negative regulation of adaptive immune response	4.842237e-4
GO:0009119	ribonucleoside metabolic process	5.035914e-4
GO:0045671	negative regulation of osteoclast differentiation	5.138099e-4
GO:0030225	macrophage differentiation	5.269091e-4
GO:0032988	ribonucleoprotein complex disassembly	5.276700e-4
GO:0006508	proteolysis	5.331236e-4
GO:0010739	positive regulation of protein kinase A signaling cascade	5.410394e-4
GO:0003015	heart process	5.479822e-4
GO:0051707	response to other organism	5.638107e-4
GO:0042312	regulation of vasodilation	5.834415e-4
GO:0003254	regulation of membrane depolarization	6.093019e-4
GO:0032811	negative regulation of epinephrine secretion	6.119932e-4
GO:0031960	response to corticosteroid stimulus	6.258346e-4
GO:0071214	cellular response to abiotic stimulus	6.311698e-4
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	6.486684e-4
GO:0032048	cardiolipin metabolic process	6.486684e-4
GO:0051533	positive regulation of NFAT protein import into nucleus	6.486684e-4
GO:0019367	fatty acid elongation, saturated fatty acid	6.496508e-4
GO:0015671	oxygen transport	6.518826e-4
GO:0046513	ceramide biosynthetic process	6.523496e-4
GO:0044242	cellular lipid catabolic process	6.565052e-4
GO:0009566	fertilization	7.031227e-4
GO:0033044	regulation of chromosome organization	7.341081e-4
GO:0045900	negative regulation of translational elongation	7.448420e-4
GO:0043087	regulation of GTPase activity	7.529420e-4
GO:0015931	nucleobase-containing compound transport	7.606812e-4
GO:0010159	specification of organ position	7.871793e-4
GO:0002906	negative regulation of mature B cell apoptosis	7.937928e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	7.983779e-4
GO:0006265	DNA topological change	7.983779e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	8.202266e-4
GO:0033124	regulation of GTP catabolic process	8.220256e-4
GO:0016101	diterpenoid metabolic process	8.406873e-4
GO:2000172	regulation of branching morphogenesis of a nerve	8.432653e-4
GO:0006941	striated muscle contraction	8.497474e-4
GO:0006029	proteoglycan metabolic process	8.754667e-4
GO:0030157	pancreatic juice secretion	8.976204e-4
GO:0010269	response to selenium ion	9.132297e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	9.155068e-4
GO:0055067	monovalent inorganic cation homeostasis	9.215559e-4
GO:0010886	positive regulation of cholesterol storage	9.274886e-4
GO:0030204	chondroitin sulfate metabolic process	9.722553e-4
GO:0030832	regulation of actin filament length	9.956129e-4
GO:0001766	membrane raft polarization	1.012244e-3
GO:0000722	telomere maintenance via recombination	1.012244e-3
GO:0051409	response to nitrosative stress	1.016178e-3
GO:0015991	ATP hydrolysis coupled proton transport	1.024133e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	1.053474e-3
GO:0007601	visual perception	1.069521e-3
GO:0006497	protein lipidation	1.072095e-3
GO:0051591	response to cAMP	1.076084e-3
GO:0006707	cholesterol catabolic process	1.080971e-3
GO:0060346	bone trabecula formation	1.084470e-3
GO:0000103	sulfate assimilation	1.114043e-3
GO:0002920	regulation of humoral immune response	1.134291e-3
GO:0046519	sphingoid metabolic process	1.137324e-3
GO:0009629	response to gravity	1.139559e-3
GO:0043266	regulation of potassium ion transport	1.163002e-3
GO:0070229	negative regulation of lymphocyte apoptosis	1.174217e-3
GO:0006140	regulation of nucleotide metabolic process	1.187252e-3
GO:0046128	purine ribonucleoside metabolic process	1.197351e-3
GO:0051955	regulation of amino acid transport	1.229189e-3
GO:0035067	negative regulation of histone acetylation	1.239150e-3
GO:0015860	purine nucleoside transport	1.262655e-3
GO:0009125	nucleoside monophosphate catabolic process	1.267036e-3
GO:0014075	response to amine stimulus	1.267448e-3
GO:0071320	cellular response to cAMP	1.278994e-3
GO:0002902	regulation of B cell apoptosis	1.278994e-3
GO:0046824	positive regulation of nucleocytoplasmic transport	1.309316e-3
GO:0042753	positive regulation of circadian rhythm	1.312048e-3
GO:0030838	positive regulation of actin filament polymerization	1.327746e-3
GO:0032715	negative regulation of interleukin-6 production	1.355329e-3
GO:0072659	protein localization in plasma membrane	1.356631e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	1.363236e-3
GO:0005975	carbohydrate metabolic process	1.383808e-3
GO:0043085	positive regulation of catalytic activity	1.413649e-3
GO:0033260	DNA replication involved in S phase	1.415637e-3
GO:0031275	regulation of lateral pseudopodium assembly	1.415637e-3
GO:0006916	anti-apoptosis	1.419215e-3
GO:2000107	negative regulation of leukocyte apoptosis	1.484061e-3
GO:0031953	negative regulation of protein autophosphorylation	1.484803e-3
GO:0072594	establishment of protein localization to organelle	1.496568e-3
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.505839e-3
GO:0002347	response to tumor cell	1.508293e-3
GO:0002115	store-operated calcium entry	1.508293e-3
GO:0050953	sensory perception of light stimulus	1.508544e-3
GO:0033979	box H/ACA snoRNA metabolic process	1.520535e-3
GO:0032900	negative regulation of neurotrophin production	1.520535e-3
GO:0032244	positive regulation of nucleoside transport	1.520535e-3
GO:0033121	regulation of purine nucleotide catabolic process	1.535347e-3
GO:0032319	regulation of Rho GTPase activity	1.543420e-3
GO:0050864	regulation of B cell activation	1.558438e-3
GO:0071377	cellular response to glucagon stimulus	1.560777e-3
GO:0003166	bundle of His development	1.561545e-3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	1.593471e-3
GO:0030206	chondroitin sulfate biosynthetic process	1.601410e-3
GO:0051665	membrane raft localization	1.701535e-3
GO:0065007	biological regulation	1.752475e-3
GO:0032388	positive regulation of intracellular transport	1.760876e-3
GO:0008654	phospholipid biosynthetic process	1.762133e-3
GO:0030261	chromosome condensation	1.802216e-3
GO:0060272	embryonic skeletal joint morphogenesis	1.804724e-3
GO:0032855	positive regulation of Rac GTPase activity	1.827159e-3
GO:0019377	glycolipid catabolic process	1.838274e-3
GO:0042940	D-amino acid transport	1.847412e-3
GO:0070779	D-aspartate import	1.873784e-3
GO:0061370	testosterone biosynthetic process	1.880488e-3
GO:0002710	negative regulation of T cell mediated immunity	1.929683e-3
GO:0051704	multi-organism process	1.945237e-3
GO:0006874	cellular calcium ion homeostasis	1.945759e-3
GO:0046636	negative regulation of alpha-beta T cell activation	1.948418e-3
GO:0060348	bone development	1.974919e-3
GO:0051182	coenzyme transport	1.975265e-3
GO:0003161	cardiac conduction system development	1.978389e-3
GO:0010716	negative regulation of extracellular matrix disassembly	1.994386e-3
GO:0002036	regulation of L-glutamate transport	1.994386e-3
GO:0006687	glycosphingolipid metabolic process	2.095859e-3
GO:0009617	response to bacterium	2.114909e-3
GO:0006534	cysteine metabolic process	2.139945e-3
GO:0072503	cellular divalent inorganic cation homeostasis	2.156314e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	2.184108e-3
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	2.192519e-3
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	2.206299e-3
GO:0035458	cellular response to interferon-beta	2.294170e-3
GO:0031508	centromeric heterochromatin formation	2.319855e-3
GO:0043312	neutrophil degranulation	2.319855e-3
GO:0034383	low-density lipoprotein particle clearance	2.356556e-3
GO:0031652	positive regulation of heat generation	2.362119e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2.374756e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.374756e-3
GO:0051260	protein homooligomerization	2.378602e-3
GO:0055114	oxidation-reduction process	2.384058e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	2.385733e-3
GO:0046033	AMP metabolic process	2.388124e-3
GO:0045601	regulation of endothelial cell differentiation	2.401890e-3
GO:0030003	cellular cation homeostasis	2.438786e-3
GO:0030833	regulation of actin filament polymerization	2.498891e-3
GO:0001542	ovulation from ovarian follicle	2.509586e-3
GO:0032801	receptor catabolic process	2.536389e-3
GO:0016559	peroxisome fission	2.601990e-3
GO:0032320	positive regulation of Ras GTPase activity	2.611660e-3
GO:0006603	phosphocreatine metabolic process	2.649204e-3
GO:0016042	lipid catabolic process	2.693048e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	2.695899e-3
GO:0072498	embryonic skeletal joint development	2.734739e-3
GO:0002551	mast cell chemotaxis	2.760044e-3
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	2.760044e-3
GO:0002706	regulation of lymphocyte mediated immunity	2.820153e-3
GO:0045059	positive thymic T cell selection	2.889259e-3
GO:0016180	snRNA processing	2.934894e-3
GO:0033198	response to ATP	2.955663e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	2.956153e-3
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.969907e-3
GO:0006898	receptor-mediated endocytosis	2.973291e-3
GO:0007052	mitotic spindle organization	2.975028e-3
GO:0070198	protein localization to chromosome, telomeric region	2.976413e-3
GO:0046477	glycosylceramide catabolic process	2.976413e-3
GO:0040016	embryonic cleavage	2.976413e-3
GO:0010508	positive regulation of autophagy	3.004582e-3
GO:0015937	coenzyme A biosynthetic process	3.043739e-3
GO:0008207	C21-steroid hormone metabolic process	3.080181e-3
GO:0071345	cellular response to cytokine stimulus	3.080541e-3
GO:0072655	establishment of protein localization in mitochondrion	3.129247e-3
GO:0048302	regulation of isotype switching to IgG isotypes	3.212572e-3
GO:0000050	urea cycle	3.260768e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.264247e-3
GO:0009082	branched chain family amino acid biosynthetic process	3.273844e-3
GO:0035457	cellular response to interferon-alpha	3.319869e-3
GO:0016557	peroxisome membrane biogenesis	3.319869e-3
GO:0031348	negative regulation of defense response	3.348184e-3
GO:0033762	response to glucagon stimulus	3.352625e-3
GO:0006664	glycolipid metabolic process	3.442813e-3
GO:0032049	cardiolipin biosynthetic process	3.463053e-3
GO:0043300	regulation of leukocyte degranulation	3.513262e-3
GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	3.522735e-3
GO:0010884	positive regulation of lipid storage	3.525161e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.548017e-3
GO:0061046	regulation of branching involved in lung morphogenesis	3.559269e-3
GO:0045948	positive regulation of translational initiation	3.559269e-3
GO:0002682	regulation of immune system process	3.899397e-3
GO:0006612	protein targeting to membrane	3.956785e-3
GO:0072507	divalent inorganic cation homeostasis	4.010328e-3
GO:0046085	adenosine metabolic process	4.028587e-3
GO:0010592	positive regulation of lamellipodium assembly	4.028587e-3
GO:0043604	amide biosynthetic process	4.036716e-3
GO:0006775	fat-soluble vitamin metabolic process	4.050417e-3
GO:0035617	stress granule disassembly	4.069055e-3
GO:0010659	cardiac muscle cell apoptosis	4.069055e-3
GO:0045055	regulated secretory pathway	4.098933e-3
GO:0045603	positive regulation of endothelial cell differentiation	4.109200e-3
GO:0006721	terpenoid metabolic process	4.134480e-3
GO:0033604	negative regulation of catecholamine secretion	4.138091e-3
GO:0051222	positive regulation of protein transport	4.148104e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	4.165700e-3
GO:0002683	negative regulation of immune system process	4.165714e-3
GO:0043299	leukocyte degranulation	4.176340e-3
GO:0048855	adenohypophysis morphogenesis	4.199591e-3
GO:0050658	RNA transport	4.204589e-3
GO:0001906	cell killing	4.211873e-3
GO:0007619	courtship behavior	4.215084e-3
GO:0006686	sphingomyelin biosynthetic process	4.248685e-3
GO:0046939	nucleotide phosphorylation	4.248685e-3
GO:0009214	cyclic nucleotide catabolic process	4.273818e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	4.298983e-3
GO:0042180	cellular ketone metabolic process	4.359402e-3
GO:0008064	regulation of actin polymerization or depolymerization	4.381661e-3
GO:0001915	negative regulation of T cell mediated cytotoxicity	4.419910e-3
GO:0060136	embryonic process involved in female pregnancy	4.454274e-3
GO:0007000	nucleolus organization	4.460791e-3
GO:0010963	regulation of L-arginine import	4.460791e-3
GO:0051336	regulation of hydrolase activity	4.523854e-3
GO:0034764	positive regulation of transmembrane transport	4.527609e-3
GO:0032862	activation of Rho GTPase activity	4.559867e-3
GO:0050873	brown fat cell differentiation	4.581454e-3
GO:0000237	leptotene	4.593985e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	4.617368e-3
GO:0045994	positive regulation of translational initiation by iron	4.617368e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	4.617368e-3
GO:0002037	negative regulation of L-glutamate transport	4.617368e-3
GO:0031247	actin rod assembly	4.617368e-3
GO:0072321	chaperone-mediated protein transport	4.676704e-3
GO:0061088	regulation of sequestering of zinc ion	4.676704e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	4.676704e-3
GO:0006312	mitotic recombination	4.676704e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	4.676704e-3
GO:0007254	JNK cascade	4.706354e-3
GO:0032890	regulation of organic acid transport	4.733125e-3
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.789772e-3
GO:0006887	exocytosis	4.811258e-3
GO:0051318	G1 phase	4.852437e-3
GO:0090316	positive regulation of intracellular protein transport	4.871812e-3
GO:0014060	regulation of epinephrine secretion	5.122028e-3
GO:0001676	long-chain fatty acid metabolic process	5.134605e-3
GO:0010717	regulation of epithelial to mesenchymal transition	5.239467e-3
GO:0070585	protein localization in mitochondrion	5.279434e-3
GO:0032467	positive regulation of cytokinesis	5.293514e-3
GO:0030728	ovulation	5.404126e-3
GO:0009615	response to virus	5.429008e-3
GO:0002886	regulation of myeloid leukocyte mediated immunity	5.528804e-3
GO:0009100	glycoprotein metabolic process	5.543113e-3
GO:0045540	regulation of cholesterol biosynthetic process	5.576748e-3
GO:0060048	cardiac muscle contraction	5.606724e-3
GO:0018106	peptidyl-histidine phosphorylation	5.771820e-3
GO:0060662	salivary gland cavitation	5.771820e-3
GO:0070541	response to platinum ion	5.787985e-3
GO:0007341	penetration of zona pellucida	5.787985e-3
GO:0046520	sphingoid biosynthetic process	5.855742e-3
GO:0001889	liver development	5.887244e-3
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	5.897575e-3
GO:2000534	positive regulation of renal albumin absorption	5.897575e-3
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	5.897575e-3
GO:2000461	negative regulation of eukaryotic cell surface binding	5.897575e-3
GO:0015805	S-adenosylmethionine transport	5.897575e-3
GO:0070994	detection of oxidative stress	5.897575e-3
GO:0007600	sensory perception	5.898130e-3
GO:0019752	carboxylic acid metabolic process	5.911947e-3
GO:0060402	calcium ion transport into cytosol	5.969314e-3
GO:0044281	small molecule metabolic process	6.067988e-3
GO:0071603	endothelial cell-cell adhesion	6.099536e-3
GO:0071569	protein ufmylation	6.099536e-3
GO:0019541	propionate metabolic process	6.099536e-3
GO:0021784	postganglionic parasympathetic nervous system development	6.099536e-3
GO:0048583	regulation of response to stimulus	6.101932e-3
GO:0010243	response to organic nitrogen	6.127987e-3
GO:0006626	protein targeting to mitochondrion	6.137279e-3
GO:0071394	cellular response to testosterone stimulus	6.262874e-3
GO:0033034	positive regulation of myeloid cell apoptosis	6.262874e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	6.262874e-3
GO:0006175	dATP biosynthetic process	6.262874e-3
GO:0030166	proteoglycan biosynthetic process	6.363627e-3
GO:0019370	leukotriene biosynthetic process	6.363627e-3
GO:0035023	regulation of Rho protein signal transduction	6.393987e-3
GO:0043270	positive regulation of ion transport	6.430663e-3
GO:0007140	male meiosis	6.430710e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	6.449786e-3
GO:0032856	activation of Ras GTPase activity	6.449951e-3
GO:0061337	cardiac conduction	6.542516e-3
GO:0045060	negative thymic T cell selection	6.561120e-3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	6.567601e-3
GO:0008360	regulation of cell shape	6.663557e-3
GO:0060558	regulation of calcidiol 1-monooxygenase activity	6.706537e-3
GO:0048312	intracellular distribution of mitochondria	6.706537e-3
GO:0030497	fatty acid elongation	6.823930e-3
GO:0009628	response to abiotic stimulus	6.841531e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	6.851891e-3
GO:0016048	detection of temperature stimulus	6.877364e-3
GO:0055074	calcium ion homeostasis	6.928151e-3
GO:0007016	cytoskeletal anchoring at plasma membrane	6.938139e-3
GO:0002819	regulation of adaptive immune response	6.971904e-3
GO:0010833	telomere maintenance via telomere lengthening	7.113862e-3
GO:0032844	regulation of homeostatic process	7.160224e-3
GO:0050801	ion homeostasis	7.237426e-3
GO:0042307	positive regulation of protein import into nucleus	7.308127e-3
GO:0061008	hepaticobiliary system development	7.558562e-3
GO:0018298	protein-chromophore linkage	7.612338e-3
GO:0051716	cellular response to stimulus	7.613163e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	7.640134e-3
GO:0032891	negative regulation of organic acid transport	7.640134e-3
GO:0042228	interleukin-8 biosynthetic process	7.654341e-3
GO:0002889	regulation of immunoglobulin mediated immune response	7.662217e-3
GO:0046641	positive regulation of alpha-beta T cell proliferation	7.716368e-3
GO:0002821	positive regulation of adaptive immune response	7.732276e-3
GO:0006370	mRNA capping	7.735109e-3
GO:0044091	membrane biogenesis	7.735109e-3
GO:0006936	muscle contraction	7.803326e-3
GO:0072240	metanephric DCT cell differentiation	7.828021e-3
GO:0072227	metanephric macula densa development	7.828021e-3
GO:0002028	regulation of sodium ion transport	7.929193e-3
GO:0070672	response to interleukin-15	8.069850e-3
GO:2000465	regulation of glycogen (starch) synthase activity	8.074200e-3
GO:0014050	negative regulation of glutamate secretion	8.142935e-3
GO:0010447	response to acidity	8.142935e-3
GO:0008050	female courtship behavior	8.142935e-3
GO:0034694	response to prostaglandin stimulus	8.163612e-3
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	8.258679e-3
GO:0043305	negative regulation of mast cell degranulation	8.307988e-3
GO:0006685	sphingomyelin catabolic process	8.307988e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	8.307988e-3
GO:0034139	regulation of toll-like receptor 3 signaling pathway	8.323409e-3
GO:0007589	body fluid secretion	8.324822e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	8.382089e-3
GO:0016073	snRNA metabolic process	8.382089e-3
GO:0007051	spindle organization	8.428214e-3
GO:0006875	cellular metal ion homeostasis	8.434713e-3
GO:0010959	regulation of metal ion transport	8.468000e-3
GO:0042752	regulation of circadian rhythm	8.704888e-3
GO:0051701	interaction with host	8.734332e-3
GO:0006241	CTP biosynthetic process	8.738970e-3
GO:0000279	M phase	8.743764e-3
GO:0090361	regulation of platelet-derived growth factor production	8.824543e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	8.824543e-3
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	8.824543e-3
GO:0006506	GPI anchor biosynthetic process	8.843380e-3
GO:0046129	purine ribonucleoside biosynthetic process	8.861361e-3
GO:0060350	endochondral bone morphogenesis	8.865412e-3
GO:0045766	positive regulation of angiogenesis	8.869025e-3
GO:0048520	positive regulation of behavior	8.900588e-3
GO:0051580	regulation of neurotransmitter uptake	8.926553e-3
GO:0060401	cytosolic calcium ion transport	8.990927e-3
GO:0006659	phosphatidylserine biosynthetic process	9.108142e-3
GO:0060349	bone morphogenesis	9.115029e-3
GO:0006950	response to stress	9.139949e-3
GO:0007040	lysosome organization	9.241624e-3
GO:0030730	sequestering of triglyceride	9.376038e-3
GO:0006012	galactose metabolic process	9.429437e-3
GO:0050728	negative regulation of inflammatory response	9.457173e-3
GO:0032205	negative regulation of telomere maintenance	9.598060e-3
GO:0071396	cellular response to lipid	9.791632e-3
GO:0060343	trabecula formation	9.803219e-3
GO:0006024	glycosaminoglycan biosynthetic process	9.849774e-3
GO:0002697	regulation of immune effector process	9.852170e-3
GO:0002645	positive regulation of tolerance induction	9.872775e-3
GO:0006106	fumarate metabolic process	9.899547e-3
GO:0007162	negative regulation of cell adhesion	1.014653e-2
GO:0009966	regulation of signal transduction	1.015357e-2
GO:0032271	regulation of protein polymerization	1.026141e-2
GO:0045058	T cell selection	1.036878e-2
GO:0006720	isoprenoid metabolic process	1.043353e-2
GO:0048311	mitochondrion distribution	1.048093e-2
GO:0006228	UTP biosynthetic process	1.048093e-2
GO:0006165	nucleoside diphosphate phosphorylation	1.048093e-2