Novel motif:40

name:	motif40_ATGCGGAGGAG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0090192	regulation of glomerulus development	1.302533e-11
GO:0072124	regulation of glomerular mesangial cell proliferation	2.475004e-11
GO:0072298	regulation of metanephric glomerulus development	5.466977e-11
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	5.886295e-10
GO:0007522	visceral muscle development	2.749827e-8
GO:0072110	glomerular mesangial cell proliferation	9.082091e-8
GO:0097116	gephyrin clustering	1.526029e-7
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	4.383875e-7
GO:0097118	neuroligin clustering	5.139192e-7
GO:0071072	negative regulation of phospholipid biosynthetic process	5.203618e-7
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	5.314211e-7
GO:0072111	cell proliferation involved in kidney development	5.571552e-7
GO:0030157	pancreatic juice secretion	7.037974e-7
GO:0071071	regulation of phospholipid biosynthetic process	7.917654e-7
GO:0018277	protein deamination	8.171732e-7
GO:0097119	postsynaptic density protein 95 clustering	1.018371e-6
GO:0097104	postsynaptic membrane assembly	1.018371e-6
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.040327e-6
GO:0071506	cellular response to mycophenolic acid	1.040327e-6
GO:0033084	regulation of immature T cell proliferation in thymus	1.263754e-6
GO:0010624	regulation of Schwann cell proliferation	1.335047e-6
GO:0001662	behavioral fear response	2.864703e-6
GO:0006356	regulation of transcription from RNA polymerase I promoter	3.408324e-6
GO:0072125	negative regulation of glomerular mesangial cell proliferation	3.633294e-6
GO:0072109	glomerular mesangium development	3.633294e-6
GO:0090399	replicative senescence	3.740750e-6
GO:0042088	T-helper 1 type immune response	4.092504e-6
GO:0043084	penile erection	4.281342e-6
GO:0006449	regulation of translational termination	4.461284e-6
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	4.950771e-6
GO:0002209	behavioral defense response	5.915705e-6
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	5.979982e-6
GO:0043064	flagellum organization	6.904873e-6
GO:2000016	negative regulation of determination of dorsal identity	7.509501e-6
GO:0007288	sperm axoneme assembly	7.669265e-6
GO:0060251	regulation of glial cell proliferation	8.779819e-6
GO:0061003	positive regulation of dendritic spine morphogenesis	8.819624e-6
GO:0010511	regulation of phosphatidylinositol biosynthetic process	8.819624e-6
GO:0010225	response to UV-C	1.163635e-5
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.240904e-5
GO:0030509	BMP signaling pathway	1.375703e-5
GO:0071353	cellular response to interleukin-4	1.738534e-5
GO:0060999	positive regulation of dendritic spine development	1.865514e-5
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.888788e-5
GO:0043586	tongue development	2.247974e-5
GO:0070861	regulation of protein exit from endoplasmic reticulum	2.249820e-5
GO:0021562	vestibulocochlear nerve development	2.770328e-5
GO:0035461	vitamin transmembrane transport	2.934937e-5
GO:0016574	histone ubiquitination	2.935478e-5
GO:0060005	vestibular reflex	2.952092e-5
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	3.158205e-5
GO:0071584	negative regulation of zinc ion import	3.207831e-5
GO:0090281	negative regulation of calcium ion import	3.207831e-5
GO:0071895	odontoblast differentiation	3.262737e-5
GO:0048332	mesoderm morphogenesis	3.288738e-5
GO:0070831	basement membrane assembly	3.376910e-5
GO:0035356	cellular triglyceride homeostasis	3.462916e-5
GO:0043923	positive regulation by host of viral transcription	3.571527e-5
GO:0048708	astrocyte differentiation	3.572778e-5
GO:0005983	starch catabolic process	3.575159e-5
GO:0019227	neuronal action potential propagation	3.848613e-5
GO:0032231	regulation of actin filament bundle assembly	4.011041e-5
GO:0042093	T-helper cell differentiation	4.292481e-5
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	4.416516e-5
GO:0006398	histone mRNA 3'-end processing	4.599032e-5
GO:0045843	negative regulation of striated muscle tissue development	4.636150e-5
GO:0072179	nephric duct formation	5.054568e-5
GO:0090183	regulation of kidney development	5.274499e-5
GO:0008334	histone mRNA metabolic process	5.406141e-5
GO:0001707	mesoderm formation	5.454337e-5
GO:0042596	fear response	5.483816e-5
GO:0090128	regulation of synapse maturation	5.540344e-5
GO:0003406	retinal pigment epithelium development	5.848610e-5
GO:0090086	negative regulation of protein deubiquitination	6.550673e-5
GO:0072300	positive regulation of metanephric glomerulus development	6.684892e-5
GO:0071625	vocalization behavior	6.856483e-5
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	6.856483e-5
GO:0002309	T cell proliferation involved in immune response	6.954603e-5
GO:0043543	protein acylation	7.198600e-5
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	7.807077e-5
GO:0048752	semicircular canal morphogenesis	8.723499e-5
GO:0001886	endothelial cell morphogenesis	8.811918e-5
GO:0030828	positive regulation of cGMP biosynthetic process	8.896333e-5
GO:0033233	regulation of protein sumoylation	9.428629e-5
GO:0046814	virion attachment, binding of host cell surface coreceptor	9.770113e-5
GO:0060923	cardiac muscle cell fate commitment	1.049939e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	1.143964e-4
GO:0008292	acetylcholine biosynthetic process	1.179974e-4
GO:0017145	stem cell division	1.218644e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.288917e-4
GO:0055107	Golgi to secretory granule transport	1.366099e-4
GO:2000370	positive regulation of clathrin-mediated endocytosis	1.398542e-4
GO:0014739	positive regulation of muscle hyperplasia	1.398542e-4
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1.577174e-4
GO:0043503	skeletal muscle fiber adaptation	1.737929e-4
GO:0006473	protein acetylation	1.742581e-4
GO:0010835	regulation of protein ADP-ribosylation	1.779746e-4
GO:0030223	neutrophil differentiation	1.904540e-4
GO:0032793	positive regulation of CREB transcription factor activity	1.982685e-4
GO:0006335	DNA replication-dependent nucleosome assembly	2.035334e-4
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.096310e-4
GO:0061153	trachea gland development	2.106228e-4
GO:0070079	histone H4-R3 demethylation	2.159947e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.159947e-4
GO:0070078	histone H3-R2 demethylation	2.159947e-4
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	2.159947e-4
GO:0071934	thiamine transmembrane transport	2.186051e-4
GO:0034766	negative regulation of ion transmembrane transport	2.186051e-4
GO:0003329	pancreatic PP cell fate commitment	2.305044e-4
GO:0003326	pancreatic A cell fate commitment	2.305044e-4
GO:0006513	protein monoubiquitination	2.334914e-4
GO:0071866	negative regulation of apoptosis in bone marrow	2.416458e-4
GO:0071864	positive regulation of cell proliferation in bone marrow	2.416458e-4
GO:0060710	chorio-allantoic fusion	2.557586e-4
GO:0045662	negative regulation of myoblast differentiation	2.584833e-4
GO:0006562	proline catabolic process	2.609222e-4
GO:2000573	positive regulation of DNA biosynthetic process	2.797593e-4
GO:0042593	glucose homeostasis	2.807288e-4
GO:0003180	aortic valve morphogenesis	2.948459e-4
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	3.029322e-4
GO:0033490	cholesterol biosynthetic process via lathosterol	3.029322e-4
GO:0043462	regulation of ATPase activity	3.039442e-4
GO:0061032	visceral serous pericardium development	3.091870e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	3.091870e-4
GO:2000597	positive regulation of optic nerve formation	3.091870e-4
GO:0061360	optic chiasma development	3.091870e-4
GO:0006173	dADP biosynthetic process	3.091870e-4
GO:0021633	optic nerve structural organization	3.091870e-4
GO:0021650	vestibulocochlear nerve formation	3.091870e-4
GO:0035799	ureter maturation	3.091870e-4
GO:0032656	regulation of interleukin-13 production	3.109006e-4
GO:0019064	viral envelope fusion with host membrane	3.377556e-4
GO:0035566	regulation of metanephros size	3.631237e-4
GO:0014807	regulation of somitogenesis	3.631237e-4
GO:0071539	protein localization to centrosome	3.632372e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.632372e-4
GO:0072215	regulation of metanephros development	3.653160e-4
GO:0050434	positive regulation of viral transcription	3.740821e-4
GO:0016180	snRNA processing	3.750919e-4
GO:0045657	positive regulation of monocyte differentiation	3.789750e-4
GO:0016073	snRNA metabolic process	4.007521e-4
GO:0033083	regulation of immature T cell proliferation	4.040570e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	4.055653e-4
GO:0010626	negative regulation of Schwann cell proliferation	4.637630e-4
GO:0048103	somatic stem cell division	4.639385e-4
GO:0060816	random inactivation of X chromosome	4.641753e-4
GO:0061113	pancreas morphogenesis	4.641753e-4
GO:0061157	mRNA destabilization	4.700238e-4
GO:0045090	retroviral genome replication	4.700238e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	4.700238e-4
GO:0045063	T-helper 1 cell differentiation	4.714218e-4
GO:0001941	postsynaptic membrane organization	4.938947e-4
GO:0035518	histone H2A monoubiquitination	5.035574e-4
GO:0007625	grooming behavior	5.128823e-4
GO:0097117	guanylate kinase-associated protein clustering	5.237476e-4
GO:0097114	N-methyl-D-aspartate receptor clustering	5.237476e-4
GO:0097112	gamma-aminobutyric acid receptor clustering	5.237476e-4
GO:0010719	negative regulation of epithelial to mesenchymal transition	5.287308e-4
GO:0021943	formation of radial glial scaffolds	5.322483e-4
GO:0033522	histone H2A ubiquitination	5.399053e-4
GO:0042450	arginine biosynthetic process via ornithine	5.707337e-4
GO:0010625	positive regulation of Schwann cell proliferation	5.869507e-4
GO:0050872	white fat cell differentiation	6.251007e-4
GO:0033602	negative regulation of dopamine secretion	6.592049e-4
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	6.592049e-4
GO:0007259	JAK-STAT cascade	6.686222e-4
GO:0032856	activation of Ras GTPase activity	6.722154e-4
GO:0060253	negative regulation of glial cell proliferation	6.747876e-4
GO:0090129	positive regulation of synapse maturation	6.986124e-4
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	7.016784e-4
GO:0060020	Bergmann glial cell differentiation	7.201476e-4
GO:0034723	DNA replication-dependent nucleosome organization	7.464812e-4
GO:0060242	contact inhibition	7.464812e-4
GO:0032926	negative regulation of activin receptor signaling pathway	7.697205e-4
GO:0060252	positive regulation of glial cell proliferation	8.111393e-4
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	8.151819e-4
GO:2000143	negative regulation of transcription initiation, DNA-dependent	8.353957e-4
GO:0019086	late viral mRNA transcription	8.353957e-4
GO:0060547	negative regulation of necrotic cell death	8.386187e-4
GO:0002051	osteoblast fate commitment	8.408720e-4
GO:0060561	apoptosis involved in morphogenesis	8.498757e-4
GO:0032674	regulation of interleukin-5 production	8.515350e-4
GO:0071504	cellular response to heparin	8.673378e-4
GO:0015809	arginine transport	9.143777e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	9.308785e-4
GO:0001823	mesonephros development	9.363386e-4
GO:0001974	blood vessel remodeling	9.756093e-4
GO:0097120	receptor localization to synapse	9.982535e-4
GO:0072578	neurotransmitter-gated ion channel clustering	9.982535e-4
GO:0006538	glutamate catabolic process	1.001753e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.046168e-3
GO:0043313	regulation of neutrophil degranulation	1.048446e-3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1.050432e-3
GO:0031063	regulation of histone deacetylation	1.064279e-3
GO:0009296	flagellum assembly	1.085352e-3
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	1.093807e-3
GO:0010529	negative regulation of transposition	1.127764e-3
GO:0046532	regulation of photoreceptor cell differentiation	1.136964e-3
GO:0032092	positive regulation of protein binding	1.142044e-3
GO:0035418	protein localization to synapse	1.150247e-3
GO:0070574	cadmium ion transmembrane transport	1.159677e-3
GO:0030851	granulocyte differentiation	1.170333e-3
GO:0006475	internal protein amino acid acetylation	1.176654e-3
GO:0048168	regulation of neuronal synaptic plasticity	1.197469e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	1.219956e-3
GO:0030382	sperm mitochondrion organization	1.232466e-3
GO:0051586	positive regulation of dopamine uptake	1.265007e-3
GO:0048210	Golgi vesicle fusion to target membrane	1.265007e-3
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	1.269399e-3
GO:0003062	regulation of heart rate by chemical signal	1.292845e-3
GO:0043314	negative regulation of neutrophil degranulation	1.321230e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	1.360451e-3
GO:0097105	presynaptic membrane assembly	1.375768e-3
GO:0032862	activation of Rho GTPase activity	1.457884e-3
GO:0051497	negative regulation of stress fiber assembly	1.486599e-3
GO:0048635	negative regulation of muscle organ development	1.488738e-3
GO:0034389	lipid particle organization	1.566864e-3
GO:0006268	DNA unwinding involved in replication	1.649101e-3
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	1.651775e-3
GO:0071585	detoxification of cadmium ion	1.672618e-3
GO:0048341	paraxial mesoderm formation	1.762535e-3
GO:0044258	intestinal lipid catabolic process	1.812468e-3
GO:0018350	protein esterification	1.812468e-3
GO:0009436	glyoxylate catabolic process	1.863372e-3
GO:0018364	peptidyl-glutamine methylation	1.863372e-3
GO:0003310	pancreatic A cell differentiation	1.894523e-3
GO:0072203	cell proliferation involved in metanephros development	1.896588e-3
GO:0030852	regulation of granulocyte differentiation	1.897906e-3
GO:0009299	mRNA transcription	1.923540e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.961365e-3
GO:0071503	response to heparin	2.002639e-3
GO:0045838	positive regulation of membrane potential	2.028364e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	2.043034e-3
GO:0072178	nephric duct morphogenesis	2.067863e-3
GO:0019428	allantoin biosynthetic process	2.078544e-3
GO:0072176	nephric duct development	2.140381e-3
GO:0072498	embryonic skeletal joint development	2.216727e-3
GO:0051102	DNA ligation involved in DNA recombination	2.285060e-3
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	2.304613e-3
GO:0090193	positive regulation of glomerulus development	2.304613e-3
GO:0045342	MHC class II biosynthetic process	2.336491e-3
GO:0070839	divalent metal ion export	2.336491e-3
GO:0006876	cellular cadmium ion homeostasis	2.336491e-3
GO:0043091	L-arginine import	2.336491e-3
GO:0032632	interleukin-3 production	2.336491e-3
GO:0015707	nitrite transport	2.336491e-3
GO:0006537	glutamate biosynthetic process	2.347959e-3
GO:0018205	peptidyl-lysine modification	2.409967e-3
GO:0000710	meiotic mismatch repair	2.415700e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	2.429072e-3
GO:0072075	metanephric mesenchyme development	2.442487e-3
GO:0051492	regulation of stress fiber assembly	2.480648e-3
GO:0030422	production of siRNA involved in RNA interference	2.513618e-3
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	2.563003e-3
GO:0006408	snRNA export from nucleus	2.563003e-3
GO:0090311	regulation of protein deacetylation	2.620200e-3
GO:0007064	mitotic sister chromatid cohesion	2.659605e-3
GO:0014733	regulation of skeletal muscle adaptation	2.681639e-3
GO:0030853	negative regulation of granulocyte differentiation	2.696893e-3
GO:0001710	mesodermal cell fate commitment	2.735026e-3
GO:0046341	CDP-diacylglycerol metabolic process	2.852182e-3
GO:0090278	negative regulation of peptide hormone secretion	2.904743e-3
GO:0007221	positive regulation of transcription of Notch receptor target	2.926514e-3
GO:0006654	phosphatidic acid biosynthetic process	2.930173e-3
GO:0000115	regulation of transcription involved in S phase of mitotic cell cycle	2.944799e-3
GO:0071394	cellular response to testosterone stimulus	2.986137e-3
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	3.005626e-3
GO:0060591	chondroblast differentiation	3.005721e-3
GO:0009084	glutamine family amino acid biosynthetic process	3.040491e-3
GO:0043268	positive regulation of potassium ion transport	3.077274e-3
GO:0021703	locus ceruleus development	3.099243e-3
GO:0006424	glutamyl-tRNA aminoacylation	3.099243e-3
GO:0010717	regulation of epithelial to mesenchymal transition	3.136981e-3
GO:0032233	positive regulation of actin filament bundle assembly	3.142503e-3
GO:0014037	Schwann cell differentiation	3.161350e-3
GO:0016573	histone acetylation	3.254275e-3
GO:0046473	phosphatidic acid metabolic process	3.254747e-3
GO:0050885	neuromuscular process controlling balance	3.278507e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	3.314255e-3
GO:0051318	G1 phase	3.336546e-3
GO:0030262	apoptotic nuclear change	3.403263e-3
GO:0090400	stress-induced premature senescence	3.497736e-3
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	3.619071e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	3.684431e-3
GO:0048733	sebaceous gland development	3.768045e-3
GO:0033081	regulation of T cell differentiation in thymus	3.851911e-3
GO:0051645	Golgi localization	3.903989e-3
GO:0045575	basophil activation	3.903989e-3
GO:0001694	histamine biosynthetic process	3.903989e-3
GO:0006431	methionyl-tRNA aminoacylation	3.936011e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.936011e-3
GO:0018394	peptidyl-lysine acetylation	3.948908e-3
GO:0007080	mitotic metaphase plate congression	3.957585e-3
GO:0060684	epithelial-mesenchymal cell signaling	4.021976e-3
GO:0010390	histone monoubiquitination	4.034933e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	4.052673e-3
GO:0018393	internal peptidyl-lysine acetylation	4.068139e-3
GO:0002268	follicular dendritic cell differentiation	4.087137e-3
GO:0006172	ADP biosynthetic process	4.133641e-3
GO:0014044	Schwann cell development	4.185426e-3
GO:0021535	cell migration in hindbrain	4.225344e-3
GO:0031064	negative regulation of histone deacetylation	4.234625e-3
GO:0045655	regulation of monocyte differentiation	4.299610e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	4.308957e-3
GO:0051103	DNA ligation involved in DNA repair	4.446229e-3
GO:0043243	positive regulation of protein complex disassembly	4.494797e-3
GO:0043276	anoikis	4.497584e-3
GO:2000195	negative regulation of female gonad development	4.526033e-3
GO:0060123	regulation of growth hormone secretion	4.528627e-3
GO:0072537	fibroblast activation	4.567811e-3
GO:0003094	glomerular filtration	4.567811e-3
GO:0044342	type B pancreatic cell proliferation	4.610557e-3
GO:0010918	positive regulation of mitochondrial membrane potential	4.610557e-3
GO:0035883	enteroendocrine cell differentiation	4.610557e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	4.616615e-3
GO:0030844	positive regulation of intermediate filament depolymerization	4.618349e-3
GO:0052565	response to defense-related host nitric oxide production	4.618349e-3
GO:0022011	myelination in peripheral nervous system	4.674042e-3
GO:0032696	negative regulation of interleukin-13 production	4.696515e-3
GO:0046676	negative regulation of insulin secretion	4.731551e-3
GO:0090141	positive regulation of mitochondrial fission	4.739046e-3
GO:0000255	allantoin metabolic process	4.792655e-3
GO:0045217	cell-cell junction maintenance	4.799443e-3
GO:0003416	endochondral bone growth	5.004237e-3
GO:0050775	positive regulation of dendrite morphogenesis	5.073155e-3
GO:0071955	recycling endosome to Golgi transport	5.139710e-3
GO:0034499	late endosome to Golgi transport	5.139710e-3
GO:0010735	positive regulation of transcription via serum response element binding	5.188677e-3
GO:0045618	positive regulation of keratinocyte differentiation	5.215149e-3
GO:0007621	negative regulation of female receptivity	5.215149e-3
GO:0071557	histone H3-K27 demethylation	5.313797e-3
GO:0035574	histone H4-K20 demethylation	5.313797e-3
GO:0003417	growth plate cartilage development	5.325155e-3
GO:0048069	eye pigmentation	5.410907e-3
GO:2000194	regulation of female gonad development	5.442636e-3
GO:0050748	negative regulation of lipoprotein metabolic process	5.442636e-3
GO:0007501	mesodermal cell fate specification	5.489727e-3
GO:2000272	negative regulation of receptor activity	5.511091e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	5.648263e-3
GO:0002021	response to dietary excess	5.671288e-3
GO:0055026	negative regulation of cardiac muscle tissue development	5.715654e-3
GO:0031643	positive regulation of myelination	5.715654e-3
GO:0042723	thiamine-containing compound metabolic process	5.744665e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	5.782911e-3
GO:0072095	regulation of branch elongation involved in ureteric bud branching	5.997758e-3
GO:0032796	uropod organization	6.030842e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	6.102296e-3
GO:0015747	urate transport	6.102296e-3
GO:0045078	positive regulation of interferon-gamma biosynthetic process	6.275305e-3
GO:0051081	nuclear envelope disassembly	6.340749e-3
GO:0006363	termination of RNA polymerase I transcription	6.364106e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	6.547252e-3
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	6.567666e-3
GO:0042780	tRNA 3'-end processing	6.570877e-3
GO:0031118	rRNA pseudouridine synthesis	6.570877e-3
GO:0051793	medium-chain fatty acid catabolic process	6.570877e-3
GO:0010571	positive regulation of DNA replication involved in S phase	6.570877e-3
GO:0019068	virion assembly	6.570877e-3
GO:0009065	glutamine family amino acid catabolic process	6.588716e-3
GO:2000369	regulation of clathrin-mediated endocytosis	6.658258e-3
GO:0008291	acetylcholine metabolic process	6.677592e-3
GO:0030224	monocyte differentiation	6.700670e-3
GO:0032714	negative regulation of interleukin-5 production	6.730148e-3
GO:0006361	transcription initiation from RNA polymerase I promoter	6.772625e-3
GO:0021932	hindbrain radial glia guided cell migration	6.793727e-3
GO:0060465	pharynx development	6.850650e-3
GO:0043990	histone H2A-S1 phosphorylation	6.850650e-3
GO:0034378	chylomicron assembly	6.850650e-3
GO:0035048	splicing factor protein import into nucleus	6.850650e-3
GO:0048050	post-embryonic eye morphogenesis	6.884026e-3
GO:0035417	negative regulation of mitotic prometaphase	6.884026e-3
GO:0003017	lymph circulation	7.012582e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	7.099072e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	7.118886e-3
GO:0060272	embryonic skeletal joint morphogenesis	7.147785e-3
GO:0035082	axoneme assembly	7.265085e-3
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	7.290728e-3
GO:0042989	sequestering of actin monomers	7.379067e-3
GO:0030037	actin filament reorganization involved in cell cycle	7.473363e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.528959e-3
GO:0097090	presynaptic membrane organization	7.761125e-3
GO:0032108	negative regulation of response to nutrient levels	7.761125e-3
GO:0090161	Golgi ribbon formation	7.892124e-3
GO:0046349	amino sugar biosynthetic process	7.892124e-3
GO:0030220	platelet formation	8.013165e-3
GO:0060124	positive regulation of growth hormone secretion	8.086508e-3
GO:0006491	N-glycan processing	8.219190e-3
GO:0010159	specification of organ position	8.256448e-3
GO:0002086	diaphragm contraction	8.351428e-3
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	8.460586e-3
GO:0010034	response to acetate	8.465482e-3
GO:0070327	thyroid hormone transport	8.504408e-3
GO:0006379	mRNA cleavage	8.645547e-3
GO:0060070	canonical Wnt receptor signaling pathway	8.865042e-3
GO:0060847	endothelial cell fate specification	8.916203e-3
GO:0060220	camera-type eye photoreceptor cell fate commitment	8.916203e-3
GO:0043111	replication fork arrest	8.916203e-3
GO:0048074	negative regulation of eye pigmentation	8.916203e-3
GO:0035814	negative regulation of renal sodium excretion	8.978761e-3
GO:0090084	negative regulation of inclusion body assembly	8.995152e-3
GO:0046782	regulation of viral transcription	9.047334e-3
GO:0060376	positive regulation of mast cell differentiation	9.212880e-3
GO:0015884	folic acid transport	9.233405e-3
GO:0071732	cellular response to nitric oxide	9.233405e-3
GO:0060375	regulation of mast cell differentiation	9.314637e-3
GO:0046684	response to pyrethroid	9.314637e-3
GO:0019344	cysteine biosynthetic process	9.314637e-3
GO:0046604	positive regulation of mitotic centrosome separation	9.341902e-3
GO:0000379	tRNA-type intron splice site recognition and cleavage	9.341902e-3
GO:0006353	transcription termination, DNA-dependent	9.495381e-3
GO:0051095	regulation of helicase activity	9.495548e-3
GO:0048194	Golgi vesicle budding	9.623803e-3
GO:0045064	T-helper 2 cell differentiation	9.640483e-3
GO:0070383	DNA cytosine deamination	9.640483e-3
GO:0002315	marginal zone B cell differentiation	9.640483e-3
GO:0030073	insulin secretion	9.655522e-3
GO:0006622	protein targeting to lysosome	9.764266e-3
GO:0030825	positive regulation of cGMP metabolic process	9.902684e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	9.931340e-3
GO:0021547	midbrain-hindbrain boundary initiation	9.931340e-3
GO:0021501	prechordal plate formation	9.931340e-3
GO:0043949	regulation of cAMP-mediated signaling	9.952702e-3
GO:0000027	ribosomal large subunit assembly	1.000080e-2
GO:0016584	nucleosome positioning	1.039515e-2
GO:0060708	spongiotrophoblast differentiation	1.044299e-2
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.056284e-2
GO:0070194	synaptonemal complex disassembly	1.056284e-2
GO:2001044	regulation of integrin-mediated signaling pathway	1.070065e-2
GO:0042376	phylloquinone catabolic process	1.070065e-2
GO:0016191	synaptic vesicle uncoating	1.070065e-2
GO:0006741	NADP biosynthetic process	1.070065e-2
GO:0071899	negative regulation of estrogen receptor binding	1.070073e-2
GO:0043501	skeletal muscle adaptation	1.080406e-2
GO:0071472	cellular response to salt stress	1.083910e-2
GO:0000733	DNA strand renaturation	1.083910e-2
GO:0032232	negative regulation of actin filament bundle assembly	1.087839e-2
GO:0043570	maintenance of DNA repeat elements	1.093591e-2
GO:0043616	keratinocyte proliferation	1.095286e-2
GO:0051580	regulation of neurotransmitter uptake	1.095726e-2
GO:0021540	corpus callosum morphogenesis	1.101446e-2
GO:0051660	establishment of centrosome localization	1.101446e-2
GO:0060711	labyrinthine layer development	1.111121e-2
GO:0043966	histone H3 acetylation	1.112758e-2
GO:0035378	carbon dioxide transmembrane transport	1.113830e-2
GO:0043418	homocysteine catabolic process	1.113830e-2
GO:0035377	transepithelial water transport	1.113830e-2
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	1.113830e-2
GO:0019343	cysteine biosynthetic process via cystathionine	1.113830e-2
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	1.113830e-2
GO:0006535	cysteine biosynthetic process from serine	1.113830e-2
GO:0019346	transsulfuration	1.113830e-2
GO:0006382	adenosine to inosine editing	1.152335e-2
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.159593e-2
GO:0001569	patterning of blood vessels	1.160161e-2
GO:0060350	endochondral bone morphogenesis	1.165303e-2
GO:0051279	regulation of release of sequestered calcium ion into cytosol	1.182562e-2
GO:0014015	positive regulation of gliogenesis	1.202263e-2
GO:0090403	oxidative stress-induced premature senescence	1.217438e-2
GO:0090085	regulation of protein deubiquitination	1.217438e-2
GO:0050847	progesterone receptor signaling pathway	1.220651e-2
GO:0023041	neuronal signal transduction	1.224246e-2
GO:0060023	soft palate development	1.224422e-2
GO:0055089	fatty acid homeostasis	1.227887e-2
GO:0006105	succinate metabolic process	1.238138e-2
GO:0070092	regulation of glucagon secretion	1.238423e-2
GO:0006402	mRNA catabolic process	1.254850e-2
GO:0030826	regulation of cGMP biosynthetic process	1.258545e-2
GO:0009133	nucleoside diphosphate biosynthetic process	1.265357e-2
GO:0043585	nose morphogenesis	1.265357e-2
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.268427e-2
GO:0061099	negative regulation of protein tyrosine kinase activity	1.322656e-2
GO:0032956	regulation of actin cytoskeleton organization	1.322776e-2
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	1.328903e-2
GO:0006657	CDP-choline pathway	1.328903e-2
GO:0097091	synaptic vesicle clustering	1.337062e-2
GO:0045606	positive regulation of epidermal cell differentiation	1.338801e-2
GO:0071480	cellular response to gamma radiation	1.359347e-2
GO:0071956	cellular component maintenance at cellular level	1.369300e-2
GO:0070670	response to interleukin-4	1.370831e-2
GO:0060349	bone morphogenesis	1.372045e-2
GO:0006298	mismatch repair	1.379537e-2
GO:0060713	labyrinthine layer morphogenesis	1.383820e-2
GO:0043587	tongue morphogenesis	1.385778e-2
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1.386338e-2
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	1.387819e-2
GO:0048240	sperm capacitation	1.388936e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.391609e-2
GO:0003327	type B pancreatic cell fate commitment	1.391609e-2
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.407752e-2
GO:0051099	positive regulation of binding	1.417200e-2
GO:0045616	regulation of keratinocyte differentiation	1.427834e-2
GO:0006891	intra-Golgi vesicle-mediated transport	1.437509e-2
GO:0006797	polyphosphate metabolic process	1.441672e-2
GO:0015919	peroxisomal membrane transport	1.441672e-2
GO:0042503	tyrosine phosphorylation of Stat3 protein	1.443211e-2
GO:0031532	actin cytoskeleton reorganization	1.444956e-2
GO:2000108	positive regulation of leukocyte apoptosis	1.448027e-2
GO:0007549	dosage compensation	1.458985e-2
GO:0006560	proline metabolic process	1.476144e-2
GO:0071205	protein localization to juxtaparanode region of axon	1.486823e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016579	protein deubiquitination	1.112782e-37
GO:0070646	protein modification by small protein removal	8.678876e-34
GO:0070647	protein modification by small protein conjugation or removal	1.790465e-16
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	4.487770e-11
GO:0051865	protein autoubiquitination	1.419322e-10
GO:0034442	regulation of lipoprotein oxidation	2.646448e-10
GO:0050748	negative regulation of lipoprotein metabolic process	5.907652e-9
GO:0033344	cholesterol efflux	4.023425e-8
GO:0046032	ADP catabolic process	1.062568e-7
GO:0046709	IDP catabolic process	1.062568e-7
GO:0050746	regulation of lipoprotein metabolic process	1.321818e-7
GO:0070193	synaptonemal complex organization	1.376354e-7
GO:0010896	regulation of triglyceride catabolic process	1.430183e-7
GO:0021797	forebrain anterior/posterior pattern specification	1.661094e-7
GO:0050994	regulation of lipid catabolic process	2.938952e-7
GO:0018279	protein N-linked glycosylation via asparagine	3.797668e-7
GO:0001887	selenium compound metabolic process	4.953901e-7
GO:0046929	negative regulation of neurotransmitter secretion	1.127217e-6
GO:0046031	ADP metabolic process	1.410338e-6
GO:0072166	posterior mesonephric tubule development	1.549297e-6
GO:0007129	synapsis	1.995260e-6
GO:0070192	chromosome organization involved in meiosis	2.144463e-6
GO:0031133	regulation of axon diameter	2.824929e-6
GO:0042304	regulation of fatty acid biosynthetic process	3.462650e-6
GO:0010898	positive regulation of triglyceride catabolic process	4.112847e-6
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.333208e-6
GO:0016082	synaptic vesicle priming	4.350637e-6
GO:0043932	ossification involved in bone remodeling	5.754325e-6
GO:0046628	positive regulation of insulin receptor signaling pathway	7.074438e-6
GO:0032536	regulation of cell projection size	7.288839e-6
GO:0002036	regulation of L-glutamate transport	7.477210e-6
GO:0006601	creatine biosynthetic process	8.103935e-6
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	8.799893e-6
GO:0006982	response to lipid hydroperoxide	1.032615e-5
GO:0060674	placenta blood vessel development	1.176178e-5
GO:0006342	chromatin silencing	1.212223e-5
GO:2001076	positive regulation of metanephric ureteric bud development	1.332516e-5
GO:0007356	thorax and anterior abdomen determination	1.332516e-5
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.332516e-5
GO:0008616	queuosine biosynthetic process	1.445581e-5
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.735640e-5
GO:0051026	chiasma assembly	1.737120e-5
GO:0032849	positive regulation of cellular pH reduction	1.795044e-5
GO:0065005	protein-lipid complex assembly	1.798932e-5
GO:0006344	maintenance of chromatin silencing	1.820822e-5
GO:0045046	protein import into peroxisome membrane	1.837551e-5
GO:0006188	IMP biosynthetic process	2.804581e-5
GO:0007130	synaptonemal complex assembly	2.880048e-5
GO:0090177	establishment of planar polarity involved in neural tube closure	2.917096e-5
GO:0021516	dorsal spinal cord development	3.231625e-5
GO:0035021	negative regulation of Rac protein signal transduction	4.164515e-5
GO:0007354	zygotic determination of anterior/posterior axis, embryo	4.264503e-5
GO:0090140	regulation of mitochondrial fission	4.425364e-5
GO:0008617	guanosine metabolic process	4.425364e-5
GO:0050995	negative regulation of lipid catabolic process	4.681392e-5
GO:0033127	regulation of histone phosphorylation	4.754345e-5
GO:0045922	negative regulation of fatty acid metabolic process	5.120147e-5
GO:0090083	regulation of inclusion body assembly	5.385473e-5
GO:0021528	commissural neuron differentiation in spinal cord	5.983626e-5
GO:0021965	spinal cord ventral commissure morphogenesis	6.697514e-5
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	6.850525e-5
GO:0009088	threonine biosynthetic process	7.156957e-5
GO:0032648	regulation of interferon-beta production	7.676113e-5
GO:0051168	nuclear export	8.549030e-5
GO:0006189	'de novo' IMP biosynthetic process	9.064636e-5
GO:0006290	pyrimidine dimer repair	9.401064e-5
GO:0060716	labyrinthine layer blood vessel development	1.027075e-4
GO:0051004	regulation of lipoprotein lipase activity	1.055663e-4
GO:0032312	regulation of ARF GTPase activity	1.090303e-4
GO:0070265	necrotic cell death	1.096859e-4
GO:0045109	intermediate filament organization	1.146153e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	1.221345e-4
GO:0008088	axon cargo transport	1.253955e-4
GO:0045787	positive regulation of cell cycle	1.271306e-4
GO:0090141	positive regulation of mitochondrial fission	1.430463e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.461773e-4
GO:0002701	negative regulation of production of molecular mediator of immune response	1.556138e-4
GO:0002227	innate immune response in mucosa	1.625371e-4
GO:0051006	positive regulation of lipoprotein lipase activity	1.649275e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.701811e-4
GO:0031440	regulation of mRNA 3'-end processing	1.709394e-4
GO:0002467	germinal center formation	1.736565e-4
GO:0035249	synaptic transmission, glutamatergic	1.817160e-4
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.888739e-4
GO:0043303	mast cell degranulation	1.896015e-4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.966680e-4
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	2.027521e-4
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	2.027521e-4
GO:0043299	leukocyte degranulation	2.030664e-4
GO:0043243	positive regulation of protein complex disassembly	2.143121e-4
GO:0030259	lipid glycosylation	2.147174e-4
GO:0018230	peptidyl-L-cysteine S-palmitoylation	2.165472e-4
GO:0016068	type I hypersensitivity	2.165472e-4
GO:0006825	copper ion transport	2.384301e-4
GO:0009134	nucleoside diphosphate catabolic process	2.554521e-4
GO:0043691	reverse cholesterol transport	2.564675e-4
GO:0051956	negative regulation of amino acid transport	2.627990e-4
GO:0046889	positive regulation of lipid biosynthetic process	2.759340e-4
GO:0090281	negative regulation of calcium ion import	2.915169e-4
GO:0071584	negative regulation of zinc ion import	2.915169e-4
GO:0015788	UDP-N-acetylglucosamine transport	2.915169e-4
GO:0015790	UDP-xylose transport	2.915169e-4
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	2.915169e-4
GO:0045429	positive regulation of nitric oxide biosynthetic process	3.050194e-4
GO:0051583	dopamine uptake	3.053833e-4
GO:0001555	oocyte growth	3.127084e-4
GO:0008156	negative regulation of DNA replication	3.159644e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	3.308342e-4
GO:0070936	protein K48-linked ubiquitination	3.392809e-4
GO:0032513	negative regulation of protein phosphatase type 2B activity	3.493832e-4
GO:0016191	synaptic vesicle uncoating	3.493832e-4
GO:0046580	negative regulation of Ras protein signal transduction	3.559877e-4
GO:0060712	spongiotrophoblast layer development	3.722225e-4
GO:0034405	response to fluid shear stress	3.771167e-4
GO:0009185	ribonucleoside diphosphate metabolic process	3.903369e-4
GO:0023021	termination of signal transduction	4.214955e-4
GO:0045055	regulated secretory pathway	4.570300e-4
GO:0006878	cellular copper ion homeostasis	4.598615e-4
GO:0060896	neural plate pattern specification	4.811292e-4
GO:0070585	protein localization in mitochondrion	4.982397e-4
GO:0002155	regulation of thyroid hormone mediated signaling pathway	5.089570e-4
GO:0035094	response to nicotine	5.160412e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	5.363048e-4
GO:0021997	neural plate axis specification	5.363048e-4
GO:0045428	regulation of nitric oxide biosynthetic process	5.510617e-4
GO:0000904	cell morphogenesis involved in differentiation	5.900050e-4
GO:0035404	histone-serine phosphorylation	6.026387e-4
GO:0021954	central nervous system neuron development	6.100002e-4
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	6.131895e-4
GO:0031929	TOR signaling cascade	6.150464e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	6.155584e-4
GO:0006406	mRNA export from nucleus	6.180507e-4
GO:0051058	negative regulation of small GTPase mediated signal transduction	6.441842e-4
GO:2000143	negative regulation of transcription initiation, DNA-dependent	6.763572e-4
GO:0045085	negative regulation of interleukin-2 biosynthetic process	6.763572e-4
GO:0032728	positive regulation of interferon-beta production	7.026224e-4
GO:0060052	neurofilament cytoskeleton organization	7.179990e-4
GO:0009817	defense response to fungus, incompatible interaction	7.198267e-4
GO:0043623	cellular protein complex assembly	7.263804e-4
GO:0010970	microtubule-based transport	7.368943e-4
GO:0010936	negative regulation of macrophage cytokine production	7.415373e-4
GO:0072268	pattern specification involved in metanephros development	7.415373e-4
GO:0044243	multicellular organismal catabolic process	7.578406e-4
GO:0033700	phospholipid efflux	7.717587e-4
GO:0042994	cytoplasmic sequestering of transcription factor	7.816797e-4
GO:0046322	negative regulation of fatty acid oxidation	8.032311e-4
GO:0002385	mucosal immune response	8.079380e-4
GO:0045875	negative regulation of sister chromatid cohesion	8.300364e-4
GO:0045925	positive regulation of female receptivity	8.781164e-4
GO:0051481	reduction of cytosolic calcium ion concentration	8.888522e-4
GO:0006654	phosphatidic acid biosynthetic process	9.342717e-4
GO:0060997	dendritic spine morphogenesis	9.777377e-4
GO:0046890	regulation of lipid biosynthetic process	9.808836e-4
GO:0060711	labyrinthine layer development	1.018581e-3
GO:0071316	cellular response to nicotine	1.059657e-3
GO:2000273	positive regulation of receptor activity	1.083701e-3
GO:0019217	regulation of fatty acid metabolic process	1.084594e-3
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1.085870e-3
GO:0006098	pentose-phosphate shunt	1.119146e-3
GO:0030573	bile acid catabolic process	1.152254e-3
GO:0002125	maternal aggressive behavior	1.152254e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	1.152254e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.153998e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.156595e-3
GO:0007630	jump response	1.156595e-3
GO:0001966	thigmotaxis	1.156595e-3
GO:0061005	cell differentiation involved in kidney development	1.188757e-3
GO:0021542	dentate gyrus development	1.193649e-3
GO:0043320	natural killer cell degranulation	1.197432e-3
GO:0045040	protein import into mitochondrial outer membrane	1.210582e-3
GO:0031442	positive regulation of mRNA 3'-end processing	1.235864e-3
GO:0042992	negative regulation of transcription factor import into nucleus	1.235946e-3
GO:0051299	centrosome separation	1.302128e-3
GO:0009191	ribonucleoside diphosphate catabolic process	1.302777e-3
GO:0009952	anterior/posterior pattern specification	1.346859e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.364895e-3
GO:0044091	membrane biogenesis	1.376409e-3
GO:0019367	fatty acid elongation, saturated fatty acid	1.376409e-3
GO:0045814	negative regulation of gene expression, epigenetic	1.413706e-3
GO:0071557	histone H3-K27 demethylation	1.442425e-3
GO:0035574	histone H4-K20 demethylation	1.442425e-3
GO:0033128	negative regulation of histone phosphorylation	1.442425e-3
GO:0031329	regulation of cellular catabolic process	1.442759e-3
GO:0071593	lymphocyte aggregation	1.443524e-3
GO:0060923	cardiac muscle cell fate commitment	1.457951e-3
GO:0006405	RNA export from nucleus	1.483223e-3
GO:0046885	regulation of hormone biosynthetic process	1.515320e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	1.518996e-3
GO:0060125	negative regulation of growth hormone secretion	1.530043e-3
GO:0051463	negative regulation of cortisol secretion	1.530043e-3
GO:2000009	negative regulation of protein localization at cell surface	1.530043e-3
GO:0007057	spindle assembly involved in female meiosis I	1.530043e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	1.530043e-3
GO:0021703	locus ceruleus development	1.530043e-3
GO:0090303	positive regulation of wound healing	1.555498e-3
GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	1.555498e-3
GO:0003002	regionalization	1.573426e-3
GO:0006513	protein monoubiquitination	1.609551e-3
GO:0002062	chondrocyte differentiation	1.618619e-3
GO:0055070	copper ion homeostasis	1.620972e-3
GO:0002251	organ or tissue specific immune response	1.620972e-3
GO:0032479	regulation of type I interferon production	1.706188e-3
GO:0000422	mitochondrion degradation	1.744212e-3
GO:0042396	phosphagen biosynthetic process	1.744212e-3
GO:2000465	regulation of glycogen (starch) synthase activity	1.768593e-3
GO:0002719	negative regulation of cytokine production involved in immune response	1.811419e-3
GO:0045862	positive regulation of proteolysis	1.831574e-3
GO:0071585	detoxification of cadmium ion	1.834043e-3
GO:0044240	multicellular organismal lipid catabolic process	1.843074e-3
GO:0010984	regulation of lipoprotein particle clearance	1.868109e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.873369e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.873369e-3
GO:0030300	regulation of intestinal cholesterol absorption	1.896236e-3
GO:0032847	regulation of cellular pH reduction	1.901125e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	1.909357e-3
GO:0090084	negative regulation of inclusion body assembly	1.935826e-3
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.936321e-3
GO:0051258	protein polymerization	1.999572e-3
GO:0006611	protein export from nucleus	2.008012e-3
GO:0050849	negative regulation of calcium-mediated signaling	2.118934e-3
GO:0051005	negative regulation of lipoprotein lipase activity	2.175840e-3
GO:0070169	positive regulation of biomineral tissue development	2.181974e-3
GO:0070831	basement membrane assembly	2.222748e-3
GO:0032203	telomere formation via telomerase	2.222748e-3
GO:0021547	midbrain-hindbrain boundary initiation	2.275142e-3
GO:0021501	prechordal plate formation	2.275142e-3
GO:0051017	actin filament bundle assembly	2.333057e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	2.375894e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.375894e-3
GO:0045994	positive regulation of translational initiation by iron	2.375894e-3
GO:0002037	negative regulation of L-glutamate transport	2.375894e-3
GO:0006540	glutamate decarboxylation to succinate	2.375894e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.375894e-3
GO:0021539	subthalamus development	2.378503e-3
GO:0070076	histone lysine demethylation	2.400651e-3
GO:0001886	endothelial cell morphogenesis	2.412581e-3
GO:0055012	ventricular cardiac muscle cell differentiation	2.461492e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	2.483025e-3
GO:0031536	positive regulation of exit from mitosis	2.604168e-3
GO:0019227	neuronal action potential propagation	2.642547e-3
GO:0035434	copper ion transmembrane transport	2.642547e-3
GO:0031103	axon regeneration	2.722824e-3
GO:0031102	neuron projection regeneration	2.802419e-3
GO:0035802	adrenal cortex formation	2.803097e-3
GO:0034259	negative regulation of Rho GTPase activity	2.886752e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	3.007853e-3
GO:0010985	negative regulation of lipoprotein particle clearance	3.071717e-3
GO:0007521	muscle cell fate determination	3.071717e-3
GO:0001963	synaptic transmission, dopaminergic	3.096478e-3
GO:0045176	apical protein localization	3.111379e-3
GO:0031331	positive regulation of cellular catabolic process	3.152905e-3
GO:0045103	intermediate filament-based process	3.317532e-3
GO:0046886	positive regulation of hormone biosynthetic process	3.337929e-3
GO:0030501	positive regulation of bone mineralization	3.345866e-3
GO:0007389	pattern specification process	3.387915e-3
GO:0042308	negative regulation of protein import into nucleus	3.406145e-3
GO:0046928	regulation of neurotransmitter secretion	3.412317e-3
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	3.455539e-3
GO:0015862	uridine transport	3.455539e-3
GO:0009296	flagellum assembly	3.465167e-3
GO:0051588	regulation of neurotransmitter transport	3.619554e-3
GO:0051298	centrosome duplication	3.631676e-3
GO:0010893	positive regulation of steroid biosynthetic process	3.650517e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	3.650742e-3
GO:0070884	regulation of calcineurin-NFAT signaling pathway	3.650742e-3
GO:0022417	protein maturation by protein folding	3.650742e-3
GO:0015781	pyrimidine nucleotide-sugar transport	3.650742e-3
GO:0043153	entrainment of circadian clock by photoperiod	3.737510e-3
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	3.737510e-3
GO:0072655	establishment of protein localization in mitochondrion	3.780770e-3
GO:0006198	cAMP catabolic process	3.781755e-3
GO:0014012	peripheral nervous system axon regeneration	3.889251e-3
GO:2000178	negative regulation of neural precursor cell proliferation	3.901452e-3
GO:0031508	centromeric heterochromatin formation	3.926969e-3
GO:0000189	MAPK import into nucleus	3.926969e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	3.926969e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.939780e-3
GO:0045585	positive regulation of cytotoxic T cell differentiation	3.940372e-3
GO:0045110	intermediate filament bundle assembly	3.940372e-3
GO:0006699	bile acid biosynthetic process	3.959008e-3
GO:0003347	epicardial cell to mesenchymal cell transition	3.959008e-3
GO:0071803	positive regulation of podosome assembly	3.962744e-3
GO:0031584	activation of phospholipase D activity	3.962744e-3
GO:0006414	translational elongation	3.974837e-3
GO:0045579	positive regulation of B cell differentiation	4.020586e-3
GO:0061032	visceral serous pericardium development	4.231446e-3
GO:0006913	nucleocytoplasmic transport	4.251605e-3
GO:0034382	chylomicron remnant clearance	4.329090e-3
GO:0060996	dendritic spine development	4.329898e-3
GO:0060193	positive regulation of lipase activity	4.381111e-3
GO:0032383	regulation of intracellular cholesterol transport	4.437417e-3
GO:0001811	negative regulation of type I hypersensitivity	4.437417e-3
GO:0002638	negative regulation of immunoglobulin production	4.437417e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	4.506964e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	4.506964e-3
GO:0035850	epithelial cell differentiation involved in kidney development	4.542403e-3
GO:0030500	regulation of bone mineralization	4.643493e-3
GO:0070574	cadmium ion transmembrane transport	4.731391e-3
GO:0070301	cellular response to hydrogen peroxide	4.806165e-3
GO:0006184	GTP catabolic process	4.853012e-3
GO:0046784	intronless viral mRNA export from host nucleus	4.952720e-3
GO:0043467	regulation of generation of precursor metabolites and energy	4.960908e-3
GO:0060421	positive regulation of heart growth	4.982281e-3
GO:0050711	negative regulation of interleukin-1 secretion	4.982281e-3
GO:0035444	nickel ion transmembrane transport	5.078955e-3
GO:0007060	male meiosis chromosome segregation	5.078955e-3
GO:0001539	ciliary or flagellar motility	5.105247e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	5.114221e-3
GO:0021871	forebrain regionalization	5.129964e-3
GO:0045723	positive regulation of fatty acid biosynthetic process	5.274369e-3
GO:2000195	negative regulation of female gonad development	5.423390e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	5.437216e-3
GO:0045576	mast cell activation	5.474013e-3
GO:0072284	metanephric S-shaped body morphogenesis	5.480687e-3
GO:0072278	metanephric comma-shaped body morphogenesis	5.480687e-3
GO:0010897	negative regulation of triglyceride catabolic process	5.480687e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.480687e-3
GO:0042711	maternal behavior	5.540751e-3
GO:0034770	histone H4-K20 methylation	5.540751e-3
GO:0046128	purine ribonucleoside metabolic process	5.562862e-3
GO:0009648	photoperiodism	5.649164e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	5.649164e-3
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	5.996052e-3
GO:0043064	flagellum organization	6.024214e-3
GO:0070167	regulation of biomineral tissue development	6.130534e-3
GO:0000209	protein polyubiquitination	6.142318e-3
GO:0006626	protein targeting to mitochondrion	6.245132e-3
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	6.321885e-3
GO:0015864	pyrimidine nucleoside transport	6.321885e-3
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	6.347381e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	6.439892e-3
GO:0071624	positive regulation of granulocyte chemotaxis	6.439892e-3
GO:0030150	protein import into mitochondrial matrix	6.439892e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	6.439892e-3
GO:0019290	siderophore biosynthetic process	6.439892e-3
GO:0002418	immune response to tumor cell	6.439892e-3
GO:0010157	response to chlorate	6.524074e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	6.524074e-3
GO:0042760	very long-chain fatty acid catabolic process	6.558976e-3
GO:0045175	basal protein localization	6.565645e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.649942e-3
GO:0051169	nuclear transport	6.733311e-3
GO:0045940	positive regulation of steroid metabolic process	6.822706e-3
GO:0060191	regulation of lipase activity	6.929160e-3
GO:0006475	internal protein amino acid acetylation	6.933250e-3
GO:0090068	positive regulation of cell cycle process	6.967303e-3
GO:0007288	sperm axoneme assembly	7.005835e-3
GO:2000822	regulation of behavioral fear response	7.096020e-3
GO:0045116	protein neddylation	7.114923e-3
GO:0043457	regulation of cellular respiration	7.114923e-3
GO:0061181	regulation of chondrocyte development	7.249637e-3
GO:2000744	positive regulation of anterior head development	7.249637e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	7.249637e-3
GO:0060028	convergent extension involved in axis elongation	7.249637e-3
GO:0019049	evasion of host defenses by virus	7.429167e-3
GO:0032713	negative regulation of interleukin-4 production	7.683158e-3
GO:0071279	cellular response to cobalt ion	7.736607e-3
GO:0070370	cellular heat acclimation	7.736607e-3
GO:0010637	negative regulation of mitochondrial fusion	7.736607e-3
GO:0043048	dolichyl monophosphate biosynthetic process	7.736607e-3
GO:0018960	4-nitrophenol metabolic process	7.736607e-3
GO:0060011	Sertoli cell proliferation	7.767609e-3
GO:0006102	isocitrate metabolic process	7.767609e-3
GO:0048050	post-embryonic eye morphogenesis	7.767609e-3
GO:0000902	cell morphogenesis	7.863556e-3
GO:0090231	regulation of spindle checkpoint	7.925888e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	7.942185e-3
GO:0060021	palate development	7.974485e-3
GO:0016079	synaptic vesicle exocytosis	7.999649e-3
GO:0032202	telomere assembly	8.244566e-3
GO:0006868	glutamine transport	8.251713e-3
GO:0034720	histone H3-K4 demethylation	8.388860e-3
GO:0007281	germ cell development	8.569011e-3
GO:0046006	regulation of activated T cell proliferation	8.630542e-3
GO:0002513	tolerance induction to self antigen	8.667745e-3
GO:0043461	proton-transporting ATP synthase complex assembly	8.667745e-3
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	8.768947e-3
GO:0034616	response to laminar fluid shear stress	8.769595e-3
GO:0046058	cAMP metabolic process	8.918873e-3
GO:0072594	establishment of protein localization to organelle	8.976500e-3
GO:0032873	negative regulation of stress-activated MAPK cascade	9.134396e-3
GO:0072521	purine-containing compound metabolic process	9.156378e-3
GO:0051131	chaperone-mediated protein complex assembly	9.202727e-3
GO:0060555	induction of necroptosis by extracellular signals	9.202727e-3
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	9.261646e-3
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	9.261646e-3
GO:0060490	lateral sprouting involved in lung morphogenesis	9.261646e-3
GO:0048105	establishment of body hair planar orientation	9.261646e-3
GO:0043697	cell dedifferentiation	9.261646e-3
GO:0046831	regulation of RNA export from nucleus	9.261646e-3
GO:0045104	intermediate filament cytoskeleton organization	9.283864e-3
GO:0034614	cellular response to reactive oxygen species	9.305940e-3
GO:0060259	regulation of feeding behavior	9.322498e-3
GO:0044058	regulation of digestive system process	9.406241e-3
GO:0033146	regulation of estrogen receptor signaling pathway	9.470498e-3
GO:0090030	regulation of steroid hormone biosynthetic process	9.572066e-3
GO:0006600	creatine metabolic process	9.639621e-3
GO:0071827	plasma lipoprotein particle organization	9.877510e-3
GO:0071711	basement membrane organization	9.879514e-3
GO:0000185	activation of MAPKKK activity	9.879514e-3
GO:0006436	tryptophanyl-tRNA aminoacylation	9.885630e-3
GO:0033211	adiponectin-mediated signaling pathway	9.899631e-3
GO:0035470	positive regulation of vascular wound healing	9.905454e-3
GO:0060821	inactivation of X chromosome by DNA methylation	9.905454e-3
GO:0045751	negative regulation of Toll signaling pathway	9.905454e-3
GO:0010616	negative regulation of cardiac muscle adaptation	9.905454e-3
GO:0019428	allantoin biosynthetic process	9.905454e-3
GO:0019858	cytosine metabolic process	9.905454e-3
GO:0018393	internal peptidyl-lysine acetylation	9.964335e-3
GO:0032446	protein modification by small protein conjugation	1.009113e-2
GO:0035562	negative regulation of chromatin binding	1.020903e-2
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	1.020903e-2
GO:0033129	positive regulation of histone phosphorylation	1.020903e-2
GO:0015891	siderophore transport	1.020903e-2
GO:0034508	centromere complex assembly	1.043113e-2
GO:0006536	glutamate metabolic process	1.044364e-2
GO:0016567	protein ubiquitination	1.058471e-2
GO:0032352	positive regulation of hormone metabolic process	1.078892e-2
GO:0072015	glomerular visceral epithelial cell development	1.087050e-2
GO:0031394	positive regulation of prostaglandin biosynthetic process	1.090712e-2
GO:0032472	Golgi calcium ion transport	1.090854e-2
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	1.090854e-2
GO:0042938	dipeptide transport	1.090854e-2
GO:0032468	Golgi calcium ion homeostasis	1.090854e-2
GO:0030026	cellular manganese ion homeostasis	1.090854e-2
GO:0009150	purine ribonucleotide metabolic process	1.098467e-2
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.102068e-2
GO:0002001	renin secretion into blood stream	1.102068e-2
GO:0032318	regulation of Ras GTPase activity	1.104628e-2
GO:0031507	heterochromatin formation	1.113042e-2
GO:0045948	positive regulation of translational initiation	1.121045e-2
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.138936e-2
GO:0007044	cell-substrate junction assembly	1.144784e-2
GO:0038007	netrin-activated signaling pathway	1.163932e-2
GO:0060696	regulation of phospholipid catabolic process	1.163948e-2
GO:0051589	negative regulation of neurotransmitter transport	1.163948e-2
GO:0051973	positive regulation of telomerase activity	1.166530e-2
GO:0042891	antibiotic transport	1.166530e-2
GO:2000300	regulation of synaptic vesicle exocytosis	1.174623e-2
GO:2000194	regulation of female gonad development	1.174623e-2
GO:0034763	negative regulation of transmembrane transport	1.202213e-2
GO:0018394	peptidyl-lysine acetylation	1.209304e-2
GO:0031330	negative regulation of cellular catabolic process	1.211801e-2
GO:0006402	mRNA catabolic process	1.227899e-2
GO:0060122	inner ear receptor stereocilium organization	1.228602e-2
GO:0006415	translational termination	1.242100e-2
GO:0060591	chondroblast differentiation	1.242100e-2
GO:0000086	G2/M transition of mitotic cell cycle	1.253533e-2
GO:0000956	nuclear-transcribed mRNA catabolic process	1.279958e-2
GO:0010469	regulation of receptor activity	1.301372e-2
GO:0090208	positive regulation of triglyceride metabolic process	1.323501e-2
GO:0051532	regulation of NFAT protein import into nucleus	1.330182e-2
GO:0007099	centriole replication	1.335271e-2
GO:0031647	regulation of protein stability	1.339791e-2
GO:0051586	positive regulation of dopamine uptake	1.340475e-2
GO:0060032	notochord regression	1.340475e-2
GO:0048667	cell morphogenesis involved in neuron differentiation	1.342850e-2
GO:0030325	adrenal gland development	1.347173e-2
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	1.364476e-2
GO:0060557	positive regulation of vitamin D biosynthetic process	1.368527e-2
GO:0044154	histone H3-K14 acetylation	1.368527e-2
GO:0072531	pyrimidine-containing compound transmembrane transport	1.384171e-2
GO:0031017	exocrine pancreas development	1.397832e-2
GO:0009954	proximal/distal pattern formation	1.438742e-2
GO:0032481	positive regulation of type I interferon production	1.444376e-2
GO:0045931	positive regulation of mitotic cell cycle	1.486105e-2
GO:0060119	inner ear receptor cell development	1.508144e-2
GO:0034377	plasma lipoprotein particle assembly	1.512848e-2
GO:0046039	GTP metabolic process	1.515385e-2
GO:0051382	kinetochore assembly	1.523467e-2
GO:0035520	monoubiquitinated protein deubiquitination	1.523467e-2
GO:0032980	keratinocyte activation	1.523467e-2
GO:0006195	purine nucleotide catabolic process	1.523552e-2
GO:0061013	regulation of mRNA catabolic process	1.527013e-2
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.533451e-2
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.533451e-2
GO:0048378	regulation of lateral mesodermal cell fate specification	1.533451e-2
GO:0000183	chromatin silencing at rDNA	1.537981e-2
GO:0048671	negative regulation of collateral sprouting	1.544657e-2
GO:0014002	astrocyte development	1.568579e-2
GO:0034369	plasma lipoprotein particle remodeling	1.589993e-2
GO:0031999	negative regulation of fatty acid beta-oxidation	1.605620e-2
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.605620e-2
GO:0008105	asymmetric protein localization	1.615237e-2
GO:0042136	neurotransmitter biosynthetic process	1.625911e-2
GO:0071352	cellular response to interleukin-2	1.628707e-2
GO:2000653	regulation of genetic imprinting	1.628707e-2
GO:0065002	intracellular protein transmembrane transport	1.628707e-2
GO:0046604	positive regulation of mitotic centrosome separation	1.628707e-2
GO:0002357	defense response to tumor cell	1.628707e-2
GO:0010891	negative regulation of sequestering of triglyceride	1.648403e-2
GO:0045924	regulation of female receptivity	1.662474e-2
GO:0009167	purine ribonucleoside monophosphate metabolic process	1.663668e-2
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.700569e-2
GO:0015804	neutral amino acid transport	1.737592e-2
GO:0019048	virus-host interaction	1.747676e-2
GO:0045806	negative regulation of endocytosis	1.762050e-2
GO:0031581	hemidesmosome assembly	1.779469e-2
GO:0048563	post-embryonic organ morphogenesis	1.779469e-2
GO:0046607	positive regulation of centrosome cycle	1.839063e-2