Novel motif:100

name:	motif100_GCYTNCTC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032863	activation of Rac GTPase activity	8.296925e-8
GO:0032862	activation of Rho GTPase activity	9.997133e-8
GO:0060216	definitive hemopoiesis	1.526459e-7
GO:0014812	muscle cell migration	2.568649e-7
GO:0018277	protein deamination	4.036051e-7
GO:0060977	coronary vasculature morphogenesis	6.060410e-7
GO:0032911	negative regulation of transforming growth factor beta1 production	9.314494e-7
GO:0043586	tongue development	1.195738e-6
GO:2000251	positive regulation of actin cytoskeleton reorganization	1.234662e-6
GO:0071934	thiamine transmembrane transport	1.378612e-6
GO:0033693	neurofilament bundle assembly	1.468194e-6
GO:0060215	primitive hemopoiesis	2.388512e-6
GO:0045109	intermediate filament organization	2.860447e-6
GO:0016241	regulation of macroautophagy	3.498727e-6
GO:0035023	regulation of Rho protein signal transduction	4.675129e-6
GO:0014909	smooth muscle cell migration	4.806595e-6
GO:0032902	nerve growth factor production	5.499771e-6
GO:0051546	keratinocyte migration	6.546410e-6
GO:0007422	peripheral nervous system development	8.714653e-6
GO:0043585	nose morphogenesis	9.023183e-6
GO:0046847	filopodium assembly	9.241085e-6
GO:0030224	monocyte differentiation	1.100784e-5
GO:0046578	regulation of Ras protein signal transduction	1.187586e-5
GO:0071529	cementum mineralization	1.233623e-5
GO:0043353	enucleate erythrocyte differentiation	1.265344e-5
GO:0060976	coronary vasculature development	1.388492e-5
GO:0072676	lymphocyte migration	1.426549e-5
GO:0071105	response to interleukin-11	1.551061e-5
GO:0035419	activation of MAPK activity involved in innate immune response	2.042465e-5
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	2.073913e-5
GO:2000467	positive regulation of glycogen (starch) synthase activity	2.264107e-5
GO:0032042	mitochondrial DNA metabolic process	3.071890e-5
GO:0090183	regulation of kidney development	3.149945e-5
GO:0045110	intermediate filament bundle assembly	3.386358e-5
GO:0030035	microspike assembly	4.427496e-5
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.493942e-5
GO:2000249	regulation of actin cytoskeleton reorganization	4.686483e-5
GO:0060443	mammary gland morphogenesis	5.250634e-5
GO:0008628	induction of apoptosis by hormones	5.592728e-5
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	5.671412e-5
GO:0032012	regulation of ARF protein signal transduction	5.712129e-5
GO:0051495	positive regulation of cytoskeleton organization	5.910637e-5
GO:0070294	renal sodium ion absorption	5.934515e-5
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	6.523569e-5
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	6.526286e-5
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	6.688834e-5
GO:0010452	histone H3-K36 methylation	7.554594e-5
GO:0031129	inductive cell-cell signaling	7.736739e-5
GO:0001575	globoside metabolic process	7.817089e-5
GO:0035752	lysosomal lumen pH elevation	7.817089e-5
GO:0000046	autophagic vacuole fusion	7.817089e-5
GO:0035441	cell migration involved in vasculogenesis	7.999657e-5
GO:0006702	androgen biosynthetic process	8.230253e-5
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	8.580593e-5
GO:0060525	prostate glandular acinus development	9.047154e-5
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	9.589169e-5
GO:0032312	regulation of ARF GTPase activity	9.666647e-5
GO:0071392	cellular response to estradiol stimulus	9.686144e-5
GO:0031017	exocrine pancreas development	1.046556e-4
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.200490e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.270572e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.270572e-4
GO:0032455	nerve growth factor processing	1.303535e-4
GO:0061143	alveolar primary septum development	1.344744e-4
GO:0007296	vitellogenesis	1.396197e-4
GO:0060426	lung vasculature development	1.455041e-4
GO:0050872	white fat cell differentiation	1.494568e-4
GO:0043587	tongue morphogenesis	1.530556e-4
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.556912e-4
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.593355e-4
GO:0030879	mammary gland development	1.600995e-4
GO:0009584	detection of visible light	1.617811e-4
GO:0002230	positive regulation of defense response to virus by host	1.629301e-4
GO:0046831	regulation of RNA export from nucleus	1.675596e-4
GO:0022011	myelination in peripheral nervous system	1.744304e-4
GO:0030834	regulation of actin filament depolymerization	1.793091e-4
GO:0014037	Schwann cell differentiation	1.800997e-4
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1.878955e-4
GO:0071243	cellular response to arsenic-containing substance	1.894937e-4
GO:0060765	regulation of androgen receptor signaling pathway	1.930998e-4
GO:0051298	centrosome duplication	2.063494e-4
GO:0003096	renal sodium ion transport	2.248558e-4
GO:0032856	activation of Ras GTPase activity	2.254296e-4
GO:0002067	glandular epithelial cell differentiation	2.264343e-4
GO:0007131	reciprocal meiotic recombination	2.365138e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	2.508993e-4
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	2.549768e-4
GO:0002031	G-protein coupled receptor internalization	2.588634e-4
GO:0060052	neurofilament cytoskeleton organization	2.617016e-4
GO:0014044	Schwann cell development	2.624571e-4
GO:0060766	negative regulation of androgen receptor signaling pathway	2.722397e-4
GO:0042733	embryonic digit morphogenesis	3.046770e-4
GO:0001702	gastrulation with mouth forming second	3.352855e-4
GO:0035914	skeletal muscle cell differentiation	3.712320e-4
GO:0019934	cGMP-mediated signaling	3.753341e-4
GO:2000110	negative regulation of macrophage apoptosis	3.758765e-4
GO:2000363	positive regulation of prostaglandin-E synthase activity	3.758765e-4
GO:0071608	macrophage inflammatory protein-1 alpha production	3.758765e-4
GO:0032498	detection of muramyl dipeptide	3.758765e-4
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	3.758765e-4
GO:0032701	negative regulation of interleukin-18 production	3.758765e-4
GO:0060687	regulation of branching involved in prostate gland morphogenesis	3.886414e-4
GO:0014902	myotube differentiation	3.892888e-4
GO:0048168	regulation of neuronal synaptic plasticity	3.994393e-4
GO:2000465	regulation of glycogen (starch) synthase activity	4.270242e-4
GO:0031334	positive regulation of protein complex assembly	4.296944e-4
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	4.351470e-4
GO:0080009	mRNA methylation	4.351470e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	4.520158e-4
GO:0060711	labyrinthine layer development	4.670877e-4
GO:0043542	endothelial cell migration	4.705423e-4
GO:0071593	lymphocyte aggregation	4.729632e-4
GO:0016242	negative regulation of macroautophagy	4.743108e-4
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	4.846883e-4
GO:0070670	response to interleukin-4	4.957937e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	5.014958e-4
GO:0001812	positive regulation of type I hypersensitivity	5.014958e-4
GO:0002065	columnar/cuboidal epithelial cell differentiation	5.075831e-4
GO:0042274	ribosomal small subunit biogenesis	5.076928e-4
GO:0045824	negative regulation of innate immune response	5.140629e-4
GO:0060713	labyrinthine layer morphogenesis	5.183331e-4
GO:0001955	blood vessel maturation	5.542711e-4
GO:0008624	induction of apoptosis by extracellular signals	5.568986e-4
GO:0008089	anterograde axon cargo transport	5.594100e-4
GO:0032956	regulation of actin cytoskeleton organization	5.839093e-4
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	5.893853e-4
GO:0045061	thymic T cell selection	6.052256e-4
GO:0043084	penile erection	6.093629e-4
GO:0071635	negative regulation of transforming growth factor beta production	6.130906e-4
GO:0060674	placenta blood vessel development	6.171683e-4
GO:0003279	cardiac septum development	6.271784e-4
GO:0050764	regulation of phagocytosis	6.571830e-4
GO:0032796	uropod organization	6.590329e-4
GO:0045332	phospholipid translocation	6.675854e-4
GO:0007028	cytoplasm organization	6.710224e-4
GO:0051450	myoblast proliferation	6.717464e-4
GO:0060742	epithelial cell differentiation involved in prostate gland development	6.885882e-4
GO:0071670	smooth muscle cell chemotaxis	7.068424e-4
GO:0060981	cell migration involved in coronary angiogenesis	7.068424e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	7.215283e-4
GO:0042552	myelination	7.615371e-4
GO:0060997	dendritic spine morphogenesis	7.620918e-4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	7.815496e-4
GO:0019067	viral assembly, maturation, egress, and release	7.831315e-4
GO:0035136	forelimb morphogenesis	8.019590e-4
GO:0061034	olfactory bulb mitral cell layer development	8.040388e-4
GO:0045163	clustering of voltage-gated potassium channels	8.040388e-4
GO:0042473	outer ear morphogenesis	8.272932e-4
GO:0060603	mammary gland duct morphogenesis	8.709950e-4
GO:0030853	negative regulation of granulocyte differentiation	8.743119e-4
GO:0050775	positive regulation of dendrite morphogenesis	8.828766e-4
GO:0001826	inner cell mass cell differentiation	8.847553e-4
GO:0006264	mitochondrial DNA replication	9.159818e-4
GO:0002698	negative regulation of immune effector process	9.274194e-4
GO:0072107	positive regulation of ureteric bud formation	9.374516e-4
GO:0071104	response to interleukin-9	9.691060e-4
GO:0048246	macrophage chemotaxis	9.733131e-4
GO:0000379	tRNA-type intron splice site recognition and cleavage	1.029175e-3
GO:0045200	establishment of neuroblast polarity	1.029175e-3
GO:0006898	receptor-mediated endocytosis	1.066056e-3
GO:0043244	regulation of protein complex disassembly	1.068465e-3
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	1.105530e-3
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	1.105530e-3
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	1.105530e-3
GO:2000786	positive regulation of autophagic vacuole assembly	1.141398e-3
GO:0007098	centrosome cycle	1.145650e-3
GO:0090030	regulation of steroid hormone biosynthetic process	1.165146e-3
GO:0043088	regulation of Cdc42 GTPase activity	1.178410e-3
GO:0070858	negative regulation of bile acid biosynthetic process	1.197747e-3
GO:0021644	vagus nerve morphogenesis	1.231718e-3
GO:0002017	regulation of blood volume by renal aldosterone	1.233096e-3
GO:0046502	uroporphyrinogen III metabolic process	1.245239e-3
GO:0048755	branching morphogenesis of a nerve	1.246870e-3
GO:0045191	regulation of isotype switching	1.285783e-3
GO:0060973	cell migration involved in heart development	1.312527e-3
GO:0042723	thiamine-containing compound metabolic process	1.329036e-3
GO:0033158	regulation of protein import into nucleus, translocation	1.337246e-3
GO:0019367	fatty acid elongation, saturated fatty acid	1.367602e-3
GO:0060056	mammary gland involution	1.369548e-3
GO:0008064	regulation of actin polymerization or depolymerization	1.403296e-3
GO:0006797	polyphosphate metabolic process	1.435285e-3
GO:0043314	negative regulation of neutrophil degranulation	1.437424e-3
GO:0048013	ephrin receptor signaling pathway	1.440449e-3
GO:0007127	meiosis I	1.466346e-3
GO:0048808	male genitalia morphogenesis	1.471938e-3
GO:0046426	negative regulation of JAK-STAT cascade	1.473715e-3
GO:0003281	ventricular septum development	1.582211e-3
GO:0019370	leukotriene biosynthetic process	1.604153e-3
GO:0016556	mRNA modification	1.622617e-3
GO:0032275	luteinizing hormone secretion	1.641675e-3
GO:0046884	follicle-stimulating hormone secretion	1.641675e-3
GO:0018352	protein-pyridoxal-5-phosphate linkage	1.641675e-3
GO:0000416	positive regulation of histone H3-K36 methylation	1.641675e-3
GO:0060263	regulation of respiratory burst	1.654571e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	1.678733e-3
GO:0015809	arginine transport	1.702837e-3
GO:0046732	active induction of host immune response by virus	1.702837e-3
GO:0032970	regulation of actin filament-based process	1.746320e-3
GO:0001732	formation of translation initiation complex	1.771531e-3
GO:0030827	negative regulation of cGMP biosynthetic process	1.785840e-3
GO:0035129	post-embryonic hindlimb morphogenesis	1.785840e-3
GO:0016575	histone deacetylation	1.810372e-3
GO:0051454	intracellular pH elevation	1.811447e-3
GO:0043648	dicarboxylic acid metabolic process	1.874065e-3
GO:0032780	negative regulation of ATPase activity	1.877481e-3
GO:0046340	diacylglycerol catabolic process	1.889590e-3
GO:0045649	regulation of macrophage differentiation	1.893423e-3
GO:0030836	positive regulation of actin filament depolymerization	1.908895e-3
GO:0048286	lung alveolus development	1.920022e-3
GO:0097152	mesenchymal cell apoptosis	1.967065e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	1.967065e-3
GO:0060982	coronary artery morphogenesis	1.967065e-3
GO:0070489	T cell aggregation	1.975321e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	1.994802e-3
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	1.996026e-3
GO:0032497	detection of lipopolysaccharide	1.996026e-3
GO:0043583	ear development	1.999117e-3
GO:0010638	positive regulation of organelle organization	2.013295e-3
GO:0071168	protein localization to chromatin	2.037071e-3
GO:0032239	regulation of nucleobase-containing compound transport	2.037071e-3
GO:0006435	threonyl-tRNA aminoacylation	2.037071e-3
GO:0002091	negative regulation of receptor internalization	2.037071e-3
GO:0061198	fungiform papilla formation	2.056361e-3
GO:0051573	negative regulation of histone H3-K9 methylation	2.076671e-3
GO:0019344	cysteine biosynthetic process	2.105524e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	2.105524e-3
GO:0060022	hard palate development	2.106158e-3
GO:0046784	intronless viral mRNA export from host nucleus	2.106158e-3
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	2.135892e-3
GO:0051056	regulation of small GTPase mediated signal transduction	2.143986e-3
GO:0010225	response to UV-C	2.202047e-3
GO:0001768	establishment of T cell polarity	2.202047e-3
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	2.221549e-3
GO:0048266	behavioral response to pain	2.271198e-3
GO:0051645	Golgi localization	2.277837e-3
GO:0043519	regulation of myosin II filament organization	2.277837e-3
GO:0010543	regulation of platelet activation	2.296890e-3
GO:0097035	regulation of membrane lipid distribution	2.343288e-3
GO:0060363	cranial suture morphogenesis	2.353920e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.385235e-3
GO:0001835	blastocyst hatching	2.399047e-3
GO:0045650	negative regulation of macrophage differentiation	2.471015e-3
GO:0007386	compartment pattern specification	2.472257e-3
GO:0034109	homotypic cell-cell adhesion	2.493705e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	2.507916e-3
GO:0045059	positive thymic T cell selection	2.536232e-3
GO:0034389	lipid particle organization	2.572877e-3
GO:0031503	protein complex localization	2.599163e-3
GO:0033089	positive regulation of T cell differentiation in thymus	2.611337e-3
GO:0060364	frontal suture morphogenesis	2.622472e-3
GO:0032534	regulation of microvillus assembly	2.635559e-3
GO:0043932	ossification involved in bone remodeling	2.642174e-3
GO:0060453	regulation of gastric acid secretion	2.696850e-3
GO:0048102	autophagic cell death	2.771980e-3
GO:0032790	ribosome disassembly	2.785979e-3
GO:0006529	asparagine biosynthetic process	2.881498e-3
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	2.881498e-3
GO:0033160	positive regulation of protein import into nucleus, translocation	2.979471e-3
GO:0090086	negative regulation of protein deubiquitination	2.987457e-3
GO:0007518	myoblast cell fate determination	2.987457e-3
GO:0070814	hydrogen sulfide biosynthetic process	2.987457e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.989547e-3
GO:0035455	response to interferon-alpha	3.011289e-3
GO:0030183	B cell differentiation	3.028877e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	3.031463e-3
GO:0010893	positive regulation of steroid biosynthetic process	3.100612e-3
GO:0006984	ER-nucleus signaling pathway	3.141311e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	3.149850e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	3.149850e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	3.149850e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	3.149850e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	3.149850e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	3.149850e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	3.149850e-3
GO:0002071	glandular epithelial cell maturation	3.149850e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	3.149850e-3
GO:0043300	regulation of leukocyte degranulation	3.296080e-3
GO:0010721	negative regulation of cell development	3.302531e-3
GO:0032727	positive regulation of interferon-alpha production	3.316037e-3
GO:0000712	resolution of meiotic recombination intermediates	3.337463e-3
GO:0007341	penetration of zona pellucida	3.375201e-3
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	3.375201e-3
GO:0034505	tooth mineralization	3.416037e-3
GO:0035117	embryonic arm morphogenesis	3.424099e-3
GO:0014014	negative regulation of gliogenesis	3.445610e-3
GO:0031929	TOR signaling cascade	3.457280e-3
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	3.472525e-3
GO:0019896	axon transport of mitochondrion	3.522257e-3
GO:0090042	tubulin deacetylation	3.554101e-3
GO:0070846	Hsp90 deacetylation	3.554101e-3
GO:0060209	estrus	3.554101e-3
GO:0070407	oxidation-dependent protein catabolic process	3.554101e-3
GO:0070831	basement membrane assembly	3.554101e-3
GO:0022617	extracellular matrix disassembly	3.608295e-3
GO:0008366	axon ensheathment	3.627939e-3
GO:0007172	signal complex assembly	3.654286e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	3.916675e-3
GO:0006554	lysine catabolic process	3.952305e-3
GO:0051764	actin crosslink formation	3.967715e-3
GO:0018023	peptidyl-lysine trimethylation	3.981178e-3
GO:0072215	regulation of metanephros development	4.025329e-3
GO:0051323	metaphase	4.232677e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	4.240705e-3
GO:0031063	regulation of histone deacetylation	4.257596e-3
GO:0060555	induction of necroptosis by extracellular signals	4.287106e-3
GO:0071897	DNA biosynthetic process	4.302448e-3
GO:0042593	glucose homeostasis	4.324275e-3
GO:0009200	deoxyribonucleoside triphosphate metabolic process	4.344819e-3
GO:0060021	palate development	4.355184e-3
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	4.381230e-3
GO:0032287	peripheral nervous system myelin maintenance	4.381230e-3
GO:0046006	regulation of activated T cell proliferation	4.431735e-3
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	4.433511e-3
GO:0061196	fungiform papilla development	4.455313e-3
GO:0043313	regulation of neutrophil degranulation	4.455313e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	4.485757e-3
GO:0051295	establishment of meiotic spindle localization	4.485757e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	4.515656e-3
GO:0031297	replication fork processing	4.563968e-3
GO:0010616	negative regulation of cardiac muscle adaptation	4.594515e-3
GO:0021943	formation of radial glial scaffolds	4.598369e-3
GO:0032855	positive regulation of Rac GTPase activity	4.763336e-3
GO:0000018	regulation of DNA recombination	4.800767e-3
GO:0030490	maturation of SSU-rRNA	4.929114e-3
GO:0048568	embryonic organ development	4.935288e-3
GO:0061180	mammary gland epithelium development	4.963017e-3
GO:0030098	lymphocyte differentiation	4.992223e-3
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	5.013642e-3
GO:0045720	negative regulation of integrin biosynthetic process	5.013642e-3
GO:0019102	male somatic sex determination	5.013642e-3
GO:0035048	splicing factor protein import into nucleus	5.067088e-3
GO:0007569	cell aging	5.072031e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	5.158302e-3
GO:0090245	axis elongation involved in somitogenesis	5.158302e-3
GO:0001808	negative regulation of type IV hypersensitivity	5.158302e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	5.194428e-3
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	5.214010e-3
GO:0050902	leukocyte adhesive activation	5.214010e-3
GO:0008049	male courtship behavior	5.300634e-3
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	5.300634e-3
GO:0006781	succinyl-CoA pathway	5.300634e-3
GO:0015914	phospholipid transport	5.345960e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	5.378196e-3
GO:0006939	smooth muscle contraction	5.438600e-3
GO:0050766	positive regulation of phagocytosis	5.453435e-3
GO:0014013	regulation of gliogenesis	5.534447e-3
GO:0030208	dermatan sulfate biosynthetic process	5.608670e-3
GO:0010034	response to acetate	5.608670e-3
GO:0060688	regulation of morphogenesis of a branching structure	5.662121e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	5.704703e-3
GO:0030838	positive regulation of actin filament polymerization	5.708372e-3
GO:0048167	regulation of synaptic plasticity	5.764373e-3
GO:0048562	embryonic organ morphogenesis	5.910268e-3
GO:0016539	intein-mediated protein splicing	5.944496e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.997475e-3
GO:0032273	positive regulation of protein polymerization	6.082772e-3
GO:0006476	protein deacetylation	6.098224e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	6.114524e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	6.249791e-3
GO:0035247	peptidyl-arginine omega-N-methylation	6.347495e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	6.437780e-3
GO:0030835	negative regulation of actin filament depolymerization	6.459693e-3
GO:0001921	positive regulation of receptor recycling	6.532723e-3
GO:0045104	intermediate filament cytoskeleton organization	6.667534e-3
GO:0002521	leukocyte differentiation	6.685253e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	6.702392e-3
GO:0006704	glucocorticoid biosynthetic process	6.781444e-3
GO:0060596	mammary placode formation	6.843295e-3
GO:0001570	vasculogenesis	6.926095e-3
GO:0060439	trachea morphogenesis	6.951223e-3
GO:0010592	positive regulation of lamellipodium assembly	6.964049e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	7.005281e-3
GO:0043476	pigment accumulation	7.113071e-3
GO:0043482	cellular pigment accumulation	7.113071e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	7.113071e-3
GO:0035601	protein deacylation	7.223846e-3
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	7.341491e-3
GO:0045608	negative regulation of auditory receptor cell differentiation	7.362586e-3
GO:0071407	cellular response to organic cyclic compound	7.410038e-3
GO:0060816	random inactivation of X chromosome	7.460812e-3
GO:0060840	artery development	7.501974e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	7.516533e-3
GO:0044088	regulation of vacuole organization	7.516533e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	7.516533e-3
GO:0001805	positive regulation of type III hypersensitivity	7.516533e-3
GO:0002431	Fc receptor mediated stimulatory signaling pathway	7.516533e-3
GO:0016046	detection of fungus	7.516533e-3
GO:0046415	urate metabolic process	7.575000e-3
GO:0021861	forebrain radial glial cell differentiation	7.579859e-3
GO:0045112	integrin biosynthetic process	7.649638e-3
GO:0070845	polyubiquitinated misfolded protein transport	7.693204e-3
GO:0002537	nitric oxide production involved in inflammatory response	7.693204e-3
GO:0046070	dGTP metabolic process	7.779680e-3
GO:0051293	establishment of spindle localization	7.811985e-3
GO:0048255	mRNA stabilization	7.811985e-3
GO:0046532	regulation of photoreceptor cell differentiation	7.823724e-3
GO:0043461	proton-transporting ATP synthase complex assembly	7.861570e-3
GO:0048247	lymphocyte chemotaxis	7.867245e-3
GO:0006691	leukotriene metabolic process	7.936900e-3
GO:0030917	midbrain-hindbrain boundary development	7.947844e-3
GO:0048561	establishment of organ orientation	8.030415e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	8.030415e-3
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	8.030415e-3
GO:0001807	regulation of type IV hypersensitivity	8.030415e-3
GO:0070979	protein K11-linked ubiquitination	8.045055e-3
GO:0016191	synaptic vesicle uncoating	8.197826e-3
GO:0010793	regulation of mRNA export from nucleus	8.197826e-3
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.197826e-3
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.197826e-3
GO:0002149	hypochlorous acid biosynthetic process	8.269840e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	8.322730e-3
GO:0032490	detection of molecule of bacterial origin	8.408474e-3
GO:0035115	embryonic forelimb morphogenesis	8.486296e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	8.702225e-3
GO:0061205	paramesonephric duct development	8.847935e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	8.847935e-3
GO:0032765	positive regulation of mast cell cytokine production	8.847935e-3
GO:0051224	negative regulation of protein transport	8.855636e-3
GO:0007603	phototransduction, visible light	8.895246e-3
GO:0046902	regulation of mitochondrial membrane permeability	8.915686e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	9.072272e-3
GO:0072110	glomerular mesangial cell proliferation	9.079976e-3
GO:0032530	regulation of microvillus organization	9.079976e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	9.079976e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	9.143088e-3
GO:0042088	T-helper 1 type immune response	9.301261e-3
GO:0032964	collagen biosynthetic process	9.303569e-3
GO:0002883	regulation of hypersensitivity	9.320271e-3
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	9.406595e-3
GO:0032233	positive regulation of actin filament bundle assembly	9.485249e-3
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	9.685734e-3
GO:0001569	patterning of blood vessels	9.759308e-3
GO:0045355	negative regulation of interferon-alpha biosynthetic process	9.768286e-3
GO:0050868	negative regulation of T cell activation	9.971920e-3
GO:0006353	transcription termination, DNA-dependent	1.004308e-2
GO:0032763	regulation of mast cell cytokine production	1.007464e-2
GO:0040040	thermosensory behavior	1.012830e-2
GO:0010159	specification of organ position	1.012830e-2
GO:0072393	microtubule anchoring at microtubule organizing center	1.027430e-2
GO:0035089	establishment of apical/basal cell polarity	1.027430e-2
GO:0010572	positive regulation of platelet activation	1.039889e-2
GO:0007132	meiotic metaphase I	1.044158e-2
GO:0035640	exploration behavior	1.050684e-2
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	1.050997e-2
GO:0010912	positive regulation of isomerase activity	1.056733e-2
GO:0071353	cellular response to interleukin-4	1.057641e-2
GO:0060463	lung lobe morphogenesis	1.057641e-2
GO:0050849	negative regulation of calcium-mediated signaling	1.059595e-2
GO:0090303	positive regulation of wound healing	1.060024e-2
GO:0021932	hindbrain radial glia guided cell migration	1.061862e-2
GO:0060996	dendritic spine development	1.069587e-2
GO:0030901	midbrain development	1.072464e-2
GO:0015893	drug transport	1.084431e-2
GO:0001890	placenta development	1.116499e-2
GO:0000019	regulation of mitotic recombination	1.120217e-2
GO:0046782	regulation of viral transcription	1.121331e-2
GO:0048570	notochord morphogenesis	1.126138e-2
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	1.126138e-2
GO:0043534	blood vessel endothelial cell migration	1.133338e-2
GO:0050765	negative regulation of phagocytosis	1.138672e-2
GO:0046885	regulation of hormone biosynthetic process	1.138683e-2
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.152626e-2
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.168112e-2
GO:0050883	musculoskeletal movement, spinal reflex action	1.174288e-2
GO:0071423	malate transmembrane transport	1.174288e-2
GO:0015709	thiosulfate transport	1.174288e-2
GO:0008594	photoreceptor cell morphogenesis	1.174288e-2
GO:0060325	face morphogenesis	1.175288e-2
GO:0021936	regulation of cerebellar granule cell precursor proliferation	1.177686e-2
GO:0070483	detection of hypoxia	1.179736e-2
GO:0035461	vitamin transmembrane transport	1.182438e-2
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	1.182438e-2
GO:0060980	cell migration involved in coronary vasculogenesis	1.182438e-2
GO:0090076	relaxation of skeletal muscle	1.197162e-2
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.197162e-2
GO:0001309	age-dependent telomere shortening	1.197162e-2
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication	1.197162e-2
GO:0045940	positive regulation of steroid metabolic process	1.197277e-2
GO:0031936	negative regulation of chromatin silencing	1.198772e-2
GO:0072385	minus-end-directed organelle transport along microtubule	1.204769e-2
GO:0060754	positive regulation of mast cell chemotaxis	1.214574e-2
GO:0034969	histone arginine methylation	1.214574e-2
GO:0033121	regulation of purine nucleotide catabolic process	1.215160e-2
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.220058e-2
GO:0002762	negative regulation of myeloid leukocyte differentiation	1.220440e-2
GO:0070293	renal absorption	1.231993e-2
GO:0060710	chorio-allantoic fusion	1.245657e-2
GO:0021873	forebrain neuroblast division	1.245657e-2
GO:0090311	regulation of protein deacetylation	1.246180e-2
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	1.246601e-2
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.258105e-2
GO:0090184	positive regulation of kidney development	1.260097e-2
GO:0055123	digestive system development	1.267873e-2
GO:0071397	cellular response to cholesterol	1.283619e-2
GO:0010756	positive regulation of plasminogen activation	1.292085e-2
GO:0032225	regulation of synaptic transmission, dopaminergic	1.305560e-2
GO:0043508	negative regulation of JUN kinase activity	1.305560e-2
GO:0070857	regulation of bile acid biosynthetic process	1.312149e-2
GO:0021784	postganglionic parasympathetic nervous system development	1.312149e-2
GO:0035137	hindlimb morphogenesis	1.332125e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016579	protein deubiquitination	4.074329e-10
GO:0090201	negative regulation of release of cytochrome c from mitochondria	8.145906e-9
GO:0043471	regulation of cellular carbohydrate catabolic process	8.628653e-9
GO:0070646	protein modification by small protein removal	1.690285e-8
GO:0045351	type I interferon biosynthetic process	2.548323e-8
GO:0010823	negative regulation of mitochondrion organization	3.019485e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	7.653013e-8
GO:0060923	cardiac muscle cell fate commitment	2.237281e-7
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.292509e-7
GO:2000194	regulation of female gonad development	5.412456e-7
GO:0045869	negative regulation of retroviral genome replication	6.256341e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	6.578311e-7
GO:0010897	negative regulation of triglyceride catabolic process	6.578311e-7
GO:0006110	regulation of glycolysis	7.648458e-7
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	1.065964e-6
GO:0006297	nucleotide-excision repair, DNA gap filling	1.322222e-6
GO:0006281	DNA repair	1.337128e-6
GO:0032606	type I interferon production	1.707291e-6
GO:0046985	positive regulation of hemoglobin biosynthetic process	2.071189e-6
GO:0043973	histone H3-K4 acetylation	2.071189e-6
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	2.071189e-6
GO:2000195	negative regulation of female gonad development	2.162919e-6
GO:0035601	protein deacylation	2.535020e-6
GO:0090199	regulation of release of cytochrome c from mitochondria	3.272323e-6
GO:0010821	regulation of mitochondrion organization	3.806446e-6
GO:0016575	histone deacetylation	3.834752e-6
GO:0006476	protein deacetylation	4.784897e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	4.789367e-6
GO:0035691	macrophage migration inhibitory factor signaling pathway	4.789367e-6
GO:0051103	DNA ligation involved in DNA repair	5.604897e-6
GO:0009972	cytidine deamination	7.292511e-6
GO:0031442	positive regulation of mRNA 3'-end processing	7.445129e-6
GO:0032648	regulation of interferon-beta production	8.121634e-6
GO:0045091	regulation of retroviral genome replication	8.371647e-6
GO:0002077	acrosome matrix dispersal	8.629743e-6
GO:0050689	negative regulation of defense response to virus by host	9.089526e-6
GO:0006284	base-excision repair	1.088324e-5
GO:0010741	negative regulation of intracellular protein kinase cascade	1.182518e-5
GO:0032922	circadian regulation of gene expression	1.250495e-5
GO:0010830	regulation of myotube differentiation	1.455897e-5
GO:0060837	blood vessel endothelial cell differentiation	1.491049e-5
GO:0010501	RNA secondary structure unwinding	1.516644e-5
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.631503e-5
GO:0090022	regulation of neutrophil chemotaxis	1.686879e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	2.136056e-5
GO:0031440	regulation of mRNA 3'-end processing	2.366377e-5
GO:0015936	coenzyme A metabolic process	2.675756e-5
GO:0006266	DNA ligation	3.453610e-5
GO:0043403	skeletal muscle tissue regeneration	3.521781e-5
GO:0035623	renal glucose absorption	3.538195e-5
GO:0035621	ER to Golgi ceramide transport	3.538195e-5
GO:0043300	regulation of leukocyte degranulation	4.245414e-5
GO:0032536	regulation of cell projection size	4.358902e-5
GO:0060932	His-Purkinje system cell differentiation	4.431206e-5
GO:0060926	pacemaker cell development	4.431206e-5
GO:0042107	cytokine metabolic process	4.836027e-5
GO:0032728	positive regulation of interferon-beta production	6.065715e-5
GO:0048002	antigen processing and presentation of peptide antigen	6.712011e-5
GO:0060674	placenta blood vessel development	7.138893e-5
GO:0006783	heme biosynthetic process	7.249936e-5
GO:0003254	regulation of membrane depolarization	7.261030e-5
GO:0009119	ribonucleoside metabolic process	7.406410e-5
GO:0006914	autophagy	7.501867e-5
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	7.702906e-5
GO:0070383	DNA cytosine deamination	9.631958e-5
GO:0010529	negative regulation of transposition	9.631958e-5
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	9.693221e-5
GO:0042454	ribonucleoside catabolic process	9.752850e-5
GO:0046068	cGMP metabolic process	1.017607e-4
GO:0072125	negative regulation of glomerular mesangial cell proliferation	1.021835e-4
GO:0045819	positive regulation of glycogen catabolic process	1.022313e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.022313e-4
GO:0032836	glomerular basement membrane development	1.030129e-4
GO:0006102	isocitrate metabolic process	1.030129e-4
GO:0014894	response to denervation involved in regulation of muscle adaptation	1.030129e-4
GO:0002579	positive regulation of antigen processing and presentation	1.041665e-4
GO:0016557	peroxisome membrane biogenesis	1.061880e-4
GO:0042089	cytokine biosynthetic process	1.068576e-4
GO:0032425	positive regulation of mismatch repair	1.162544e-4
GO:0060911	cardiac cell fate commitment	1.297484e-4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.302037e-4
GO:0015684	ferrous iron transport	1.320903e-4
GO:0007492	endoderm development	1.344791e-4
GO:0060929	atrioventricular node cell fate commitment	1.387140e-4
GO:0060928	atrioventricular node cell development	1.387140e-4
GO:0003342	proepicardium development	1.387140e-4
GO:0003168	cardiac Purkinje fiber cell differentiation	1.387140e-4
GO:0046849	bone remodeling	1.433978e-4
GO:0048742	regulation of skeletal muscle fiber development	1.486480e-4
GO:0090209	negative regulation of triglyceride metabolic process	1.524897e-4
GO:0032094	response to food	1.589380e-4
GO:0007029	endoplasmic reticulum organization	1.703298e-4
GO:0007405	neuroblast proliferation	1.770291e-4
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	2.005912e-4
GO:0045401	positive regulation of interleukin-3 biosynthetic process	2.005912e-4
GO:0007126	meiosis	2.023846e-4
GO:0043409	negative regulation of MAPKKK cascade	2.048467e-4
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	2.162703e-4
GO:0003278	apoptosis involved in heart morphogenesis	2.162703e-4
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	2.263063e-4
GO:0006288	base-excision repair, DNA ligation	2.358622e-4
GO:0070293	renal absorption	2.371456e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	2.469214e-4
GO:2000142	regulation of transcription initiation, DNA-dependent	2.524622e-4
GO:0046135	pyrimidine nucleoside catabolic process	2.556029e-4
GO:0032835	glomerulus development	2.614226e-4
GO:0090310	negative regulation of methylation-dependent chromatin silencing	2.650403e-4
GO:0031327	negative regulation of cellular biosynthetic process	2.652110e-4
GO:0009948	anterior/posterior axis specification	2.893101e-4
GO:0072015	glomerular visceral epithelial cell development	2.926368e-4
GO:0031129	inductive cell-cell signaling	2.999809e-4
GO:0051321	meiotic cell cycle	3.248927e-4
GO:0043304	regulation of mast cell degranulation	3.407555e-4
GO:0060920	pacemaker cell differentiation	3.492044e-4
GO:0045338	farnesyl diphosphate metabolic process	3.499627e-4
GO:0010906	regulation of glucose metabolic process	3.565747e-4
GO:0031133	regulation of axon diameter	3.587859e-4
GO:0061014	positive regulation of mRNA catabolic process	3.617076e-4
GO:0007252	I-kappaB phosphorylation	3.617076e-4
GO:0006750	glutathione biosynthetic process	3.650353e-4
GO:0032479	regulation of type I interferon production	3.733437e-4
GO:0070374	positive regulation of ERK1 and ERK2 cascade	3.765954e-4
GO:0030002	cellular anion homeostasis	3.841311e-4
GO:0034349	glial cell apoptosis	3.856006e-4
GO:0010677	negative regulation of cellular carbohydrate metabolic process	3.905823e-4
GO:0006342	chromatin silencing	3.933515e-4
GO:0033006	regulation of mast cell activation involved in immune response	4.085309e-4
GO:0051084	'de novo' posttranslational protein folding	4.223323e-4
GO:0046128	purine ribonucleoside metabolic process	4.332313e-4
GO:0070634	transepithelial ammonium transport	4.354888e-4
GO:0045368	positive regulation of interleukin-13 biosynthetic process	4.354888e-4
GO:0042168	heme metabolic process	4.388879e-4
GO:0035518	histone H2A monoubiquitination	4.553156e-4
GO:0003166	bundle of His development	4.602395e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	4.613996e-4
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	4.613996e-4
GO:0045362	positive regulation of interleukin-1 biosynthetic process	4.613996e-4
GO:0032707	negative regulation of interleukin-23 production	4.613996e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	4.613996e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	4.635346e-4
GO:0060621	negative regulation of cholesterol import	4.635346e-4
GO:2000381	negative regulation of mesoderm development	4.644374e-4
GO:0046984	regulation of hemoglobin biosynthetic process	4.644374e-4
GO:0048286	lung alveolus development	4.676211e-4
GO:0010656	negative regulation of muscle cell apoptosis	4.859547e-4
GO:0045892	negative regulation of transcription, DNA-dependent	4.971982e-4
GO:0072112	glomerular visceral epithelial cell differentiation	4.987024e-4
GO:0046967	cytosol to ER transport	5.071310e-4
GO:0019060	intracellular transport of viral proteins in host cell	5.071310e-4
GO:0010045	response to nickel ion	5.071310e-4
GO:0010918	positive regulation of mitochondrial membrane potential	5.071310e-4
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.082821e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	5.143045e-4
GO:0015937	coenzyme A biosynthetic process	5.205554e-4
GO:0072166	posterior mesonephric tubule development	5.338682e-4
GO:0030104	water homeostasis	5.353092e-4
GO:0032743	positive regulation of interleukin-2 production	5.360386e-4
GO:0046323	glucose import	5.422232e-4
GO:0030202	heparin metabolic process	5.422232e-4
GO:2000426	negative regulation of apoptotic cell clearance	5.441535e-4
GO:0032916	positive regulation of transforming growth factor beta3 production	5.441535e-4
GO:0090023	positive regulation of neutrophil chemotaxis	5.482112e-4
GO:0006974	response to DNA damage stimulus	5.645709e-4
GO:0048641	regulation of skeletal muscle tissue development	5.833709e-4
GO:0043114	regulation of vascular permeability	5.967078e-4
GO:0072376	protein activation cascade	6.022778e-4
GO:0002577	regulation of antigen processing and presentation	6.061023e-4
GO:0034392	negative regulation of smooth muscle cell apoptosis	6.301013e-4
GO:0033522	histone H2A ubiquitination	6.308652e-4
GO:2000242	negative regulation of reproductive process	6.452175e-4
GO:0060971	embryonic heart tube left/right pattern formation	6.789679e-4
GO:0006507	GPI anchor release	6.789679e-4
GO:0034375	high-density lipoprotein particle remodeling	7.115828e-4
GO:2001022	positive regulation of response to DNA damage stimulus	7.285275e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	7.540370e-4
GO:0009890	negative regulation of biosynthetic process	7.577810e-4
GO:0009615	response to virus	7.685973e-4
GO:0070932	histone H3 deacetylation	7.774381e-4
GO:0071276	cellular response to cadmium ion	8.031484e-4
GO:0031935	regulation of chromatin silencing	8.224503e-4
GO:0060052	neurofilament cytoskeleton organization	8.686618e-4
GO:0002886	regulation of myeloid leukocyte mediated immunity	8.779717e-4
GO:0015696	ammonium transport	8.839412e-4
GO:0010623	developmental programmed cell death	9.026289e-4
GO:0072592	oxygen metabolic process	9.116137e-4
GO:2001021	negative regulation of response to DNA damage stimulus	9.606289e-4
GO:0045579	positive regulation of B cell differentiation	1.004159e-3
GO:0006109	regulation of carbohydrate metabolic process	1.005435e-3
GO:0045921	positive regulation of exocytosis	1.010377e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.015025e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.080340e-3
GO:2001076	positive regulation of metanephric ureteric bud development	1.082085e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.082085e-3
GO:0007356	thorax and anterior abdomen determination	1.082085e-3
GO:0021587	cerebellum morphogenesis	1.090086e-3
GO:0060613	fat pad development	1.090295e-3
GO:0010675	regulation of cellular carbohydrate metabolic process	1.097779e-3
GO:0051153	regulation of striated muscle cell differentiation	1.134039e-3
GO:0021697	cerebellar cortex formation	1.139432e-3
GO:0043306	positive regulation of mast cell degranulation	1.152311e-3
GO:0051253	negative regulation of RNA metabolic process	1.158023e-3
GO:0010629	negative regulation of gene expression	1.186555e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	1.191868e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.202760e-3
GO:2000648	positive regulation of stem cell proliferation	1.214328e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	1.239261e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	1.252629e-3
GO:2001038	regulation of cellular response to drug	1.252629e-3
GO:2000685	positive regulation of cellular response to X-ray	1.252629e-3
GO:0035988	chondrocyte proliferation	1.252629e-3
GO:0031052	chromosome breakage	1.252629e-3
GO:0035978	histone H2A-S139 phosphorylation	1.252629e-3
GO:0003131	mesodermal-endodermal cell signaling	1.252629e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.255133e-3
GO:0006366	transcription from RNA polymerase II promoter	1.272870e-3
GO:0010941	regulation of cell death	1.322702e-3
GO:0033005	positive regulation of mast cell activation	1.344192e-3
GO:0009164	nucleoside catabolic process	1.344192e-3
GO:0009116	nucleoside metabolic process	1.363140e-3
GO:0051126	negative regulation of actin nucleation	1.374580e-3
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.374580e-3
GO:0015693	magnesium ion transport	1.413395e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.431662e-3
GO:0055085	transmembrane transport	1.438694e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.483854e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	1.503468e-3
GO:0045357	regulation of interferon-beta biosynthetic process	1.543744e-3
GO:0043302	positive regulation of leukocyte degranulation	1.574161e-3
GO:0048712	negative regulation of astrocyte differentiation	1.593047e-3
GO:0060969	negative regulation of gene silencing	1.624873e-3
GO:0060620	regulation of cholesterol import	1.624873e-3
GO:0045820	negative regulation of glycolysis	1.653149e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.675042e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	1.749261e-3
GO:0031936	negative regulation of chromatin silencing	1.784062e-3
GO:0070372	regulation of ERK1 and ERK2 cascade	1.804746e-3
GO:0010159	specification of organ position	1.815442e-3
GO:0001869	negative regulation of complement activation, lectin pathway	1.832104e-3
GO:2000020	positive regulation of male gonad development	1.834943e-3
GO:0061013	regulation of mRNA catabolic process	1.848351e-3
GO:0070086	ubiquitin-dependent endocytosis	1.850981e-3
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.864488e-3
GO:0030513	positive regulation of BMP signaling pathway	1.909471e-3
GO:0046928	regulation of neurotransmitter secretion	1.921620e-3
GO:0006888	ER to Golgi vesicle-mediated transport	1.928535e-3
GO:0046855	inositol phosphate dephosphorylation	1.941749e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.941749e-3
GO:0070874	negative regulation of glycogen metabolic process	2.001763e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	2.011397e-3
GO:0006956	complement activation	2.044233e-3
GO:0006360	transcription from RNA polymerase I promoter	2.059819e-3
GO:0030573	bile acid catabolic process	2.061438e-3
GO:0008616	queuosine biosynthetic process	2.061438e-3
GO:0019882	antigen processing and presentation	2.081732e-3
GO:0017157	regulation of exocytosis	2.097528e-3
GO:0032663	regulation of interleukin-2 production	2.131645e-3
GO:0051932	synaptic transmission, GABAergic	2.144317e-3
GO:0006683	galactosylceramide catabolic process	2.144317e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	2.144317e-3
GO:0032321	positive regulation of Rho GTPase activity	2.155255e-3
GO:0005981	regulation of glycogen catabolic process	2.257548e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	2.265712e-3
GO:0035573	N-terminal peptidyl-serine trimethylation	2.272009e-3
GO:0035572	N-terminal peptidyl-serine dimethylation	2.272009e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	2.272009e-3
GO:0019086	late viral mRNA transcription	2.272009e-3
GO:0018012	N-terminal peptidyl-alanine trimethylation	2.272009e-3
GO:0018016	N-terminal peptidyl-proline dimethylation	2.272009e-3
GO:0048009	insulin-like growth factor receptor signaling pathway	2.317870e-3
GO:0048041	focal adhesion assembly	2.336756e-3
GO:0006642	triglyceride mobilization	2.336756e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.344904e-3
GO:0070633	transepithelial transport	2.363131e-3
GO:0070227	lymphocyte apoptosis	2.364439e-3
GO:0042246	tissue regeneration	2.424970e-3
GO:0090130	tissue migration	2.433452e-3
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	2.540276e-3
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	2.540276e-3
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	2.540276e-3
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	2.540276e-3
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	2.540276e-3
GO:0021575	hindbrain morphogenesis	2.576479e-3
GO:0015695	organic cation transport	2.589812e-3
GO:0032847	regulation of cellular pH reduction	2.592300e-3
GO:0021707	cerebellar granule cell differentiation	2.592300e-3
GO:0001780	neutrophil homeostasis	2.592300e-3
GO:0030644	cellular chloride ion homeostasis	2.593073e-3
GO:0032667	regulation of interleukin-23 production	2.622752e-3
GO:0030219	megakaryocyte differentiation	2.673081e-3
GO:0050918	positive chemotaxis	2.688945e-3
GO:0043011	myeloid dendritic cell differentiation	2.745817e-3
GO:0051147	regulation of muscle cell differentiation	2.751749e-3
GO:0032660	regulation of interleukin-17 production	2.801074e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	2.825090e-3
GO:0051984	positive regulation of chromosome segregation	2.825090e-3
GO:0000105	histidine biosynthetic process	2.825090e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	2.871762e-3
GO:0048050	post-embryonic eye morphogenesis	2.882664e-3
GO:0080135	regulation of cellular response to stress	2.895790e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2.905747e-3
GO:0002830	positive regulation of type 2 immune response	2.905747e-3
GO:0009125	nucleoside monophosphate catabolic process	2.944311e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	2.973322e-3
GO:0045767	regulation of anti-apoptosis	3.020800e-3
GO:0045839	negative regulation of mitosis	3.031973e-3
GO:0032185	septin cytoskeleton organization	3.076605e-3
GO:0032497	detection of lipopolysaccharide	3.155797e-3
GO:0043116	negative regulation of vascular permeability	3.177767e-3
GO:0070588	calcium ion transmembrane transport	3.211706e-3
GO:0022415	viral reproductive process	3.227056e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	3.274281e-3
GO:0042278	purine nucleoside metabolic process	3.357122e-3
GO:0034220	ion transmembrane transport	3.369687e-3
GO:0046671	negative regulation of retinal cell programmed cell death	3.437793e-3
GO:0010633	negative regulation of epithelial cell migration	3.437793e-3
GO:0006370	mRNA capping	3.437793e-3
GO:0001570	vasculogenesis	3.461904e-3
GO:0003097	renal water transport	3.476085e-3
GO:0043067	regulation of programmed cell death	3.561452e-3
GO:0010660	regulation of muscle cell apoptosis	3.631745e-3
GO:0002720	positive regulation of cytokine production involved in immune response	3.639254e-3
GO:0019748	secondary metabolic process	3.647669e-3
GO:0010632	regulation of epithelial cell migration	3.649585e-3
GO:0090181	regulation of cholesterol metabolic process	3.649784e-3
GO:0021683	cerebellar granular layer morphogenesis	3.653417e-3
GO:0045686	negative regulation of glial cell differentiation	3.703994e-3
GO:0015760	glucose-6-phosphate transport	3.721699e-3
GO:0007264	small GTPase mediated signal transduction	3.747438e-3
GO:0046069	cGMP catabolic process	3.859816e-3
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	3.904731e-3
GO:0014904	myotube cell development	3.996883e-3
GO:0043045	DNA methylation involved in embryo development	3.996883e-3
GO:0006188	IMP biosynthetic process	3.996883e-3
GO:0008219	cell death	4.069912e-3
GO:0070977	bone maturation	4.072714e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	4.112453e-3
GO:0016090	prenol metabolic process	4.150018e-3
GO:0042440	pigment metabolic process	4.250005e-3
GO:0072488	ammonium transmembrane transport	4.251993e-3
GO:0043467	regulation of generation of precursor metabolites and energy	4.333018e-3
GO:0030325	adrenal gland development	4.354005e-3
GO:0030320	cellular monovalent inorganic anion homeostasis	4.367395e-3
GO:0046502	uroporphyrinogen III metabolic process	4.372521e-3
GO:0015734	taurine transport	4.372521e-3
GO:0046148	pigment biosynthetic process	4.379163e-3
GO:0033151	V(D)J recombination	4.379163e-3
GO:0010760	negative regulation of macrophage chemotaxis	4.538680e-3
GO:0001787	natural killer cell proliferation	4.538680e-3
GO:0071545	inositol phosphate catabolic process	4.538749e-3
GO:0006189	'de novo' IMP biosynthetic process	4.568094e-3
GO:0046831	regulation of RNA export from nucleus	4.568094e-3
GO:0045046	protein import into peroxisome membrane	4.572935e-3
GO:0031848	protection from non-homologous end joining at telomere	4.572935e-3
GO:0016559	peroxisome fission	4.572935e-3
GO:0006119	oxidative phosphorylation	4.594029e-3
GO:0002483	antigen processing and presentation of endogenous peptide antigen	4.647377e-3
GO:0006699	bile acid biosynthetic process	4.663345e-3
GO:0014916	regulation of lung blood pressure	4.679285e-3
GO:0072091	regulation of stem cell proliferation	4.734113e-3
GO:0048332	mesoderm morphogenesis	4.902201e-3
GO:0006703	estrogen biosynthetic process	4.943063e-3
GO:0046579	positive regulation of Ras protein signal transduction	4.945607e-3
GO:0030502	negative regulation of bone mineralization	5.043452e-3
GO:0060931	sinoatrial node cell development	5.070197e-3
GO:0003167	atrioventricular bundle cell differentiation	5.070197e-3
GO:0045738	negative regulation of DNA repair	5.126413e-3
GO:0050687	negative regulation of defense response to virus	5.240932e-3
GO:0042981	regulation of apoptosis	5.244124e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	5.247704e-3
GO:0006310	DNA recombination	5.315907e-3
GO:0060038	cardiac muscle cell proliferation	5.371719e-3
GO:0032757	positive regulation of interleukin-8 production	5.535283e-3
GO:0034983	peptidyl-lysine deacetylation	5.583936e-3
GO:0016998	cell wall macromolecule catabolic process	5.596976e-3
GO:0030225	macrophage differentiation	5.636223e-3
GO:0070295	renal water absorption	5.641821e-3
GO:0034369	plasma lipoprotein particle remodeling	5.672060e-3
GO:0045087	innate immune response	5.806254e-3
GO:0060319	primitive erythrocyte differentiation	5.877149e-3
GO:0055117	regulation of cardiac muscle contraction	5.953644e-3
GO:0046329	negative regulation of JNK cascade	5.966583e-3
GO:0050916	sensory perception of sweet taste	6.015402e-3
GO:0006713	glucocorticoid catabolic process	6.015402e-3
GO:0000917	barrier septum formation	6.015402e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	6.025560e-3
GO:0035802	adrenal cortex formation	6.036536e-3
GO:0010350	cellular response to magnesium starvation	6.036536e-3
GO:0046483	heterocycle metabolic process	6.050061e-3
GO:0060442	branching involved in prostate gland morphogenesis	6.167327e-3
GO:0071577	zinc ion transmembrane transport	6.199133e-3
GO:0018108	peptidyl-tyrosine phosphorylation	6.251372e-3
GO:0060741	prostate gland stromal morphogenesis	6.262691e-3
GO:0021578	hindbrain maturation	6.262691e-3
GO:0048755	branching morphogenesis of a nerve	6.262691e-3
GO:0006784	heme a biosynthetic process	6.460239e-3
GO:0048619	embryonic hindgut morphogenesis	6.485240e-3
GO:2000781	positive regulation of double-strand break repair	6.535081e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	6.535081e-3
GO:0009786	regulation of asymmetric cell division	6.535081e-3
GO:0031468	nuclear envelope reassembly	6.535081e-3
GO:0006924	activation-induced cell death of T cells	6.558216e-3
GO:0006264	mitochondrial DNA replication	6.589300e-3
GO:0035234	germ cell programmed cell death	6.589300e-3
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	6.660501e-3
GO:0055086	nucleobase-containing small molecule metabolic process	6.700668e-3
GO:0051085	chaperone mediated protein folding requiring cofactor	6.705873e-3
GO:0045453	bone resorption	6.754588e-3
GO:0001894	tissue homeostasis	6.794715e-3
GO:0007498	mesoderm development	6.814227e-3
GO:0051973	positive regulation of telomerase activity	6.818321e-3
GO:0016265	death	6.834573e-3
GO:2000018	regulation of male gonad development	6.869101e-3
GO:0009404	toxin metabolic process	6.869101e-3
GO:0070168	negative regulation of biomineral tissue development	6.902216e-3
GO:0008595	anterior/posterior axis specification, embryo	6.915127e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	6.930515e-3
GO:0044272	sulfur compound biosynthetic process	6.968838e-3
GO:0046487	glyoxylate metabolic process	7.055358e-3
GO:0019532	oxalate transport	7.055358e-3
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	7.179040e-3
GO:0043508	negative regulation of JUN kinase activity	7.248645e-3
GO:0070141	response to UV-A	7.336070e-3
GO:0045719	negative regulation of glycogen biosynthetic process	7.336070e-3
GO:0055069	zinc ion homeostasis	7.378267e-3
GO:0007129	synapsis	7.378267e-3
GO:0048102	autophagic cell death	7.379068e-3
GO:0033235	positive regulation of protein sumoylation	7.416076e-3
GO:0070192	chromosome organization involved in meiosis	7.453109e-3
GO:0001516	prostaglandin biosynthetic process	7.453109e-3
GO:0050685	positive regulation of mRNA processing	7.594981e-3
GO:0060463	lung lobe morphogenesis	7.874755e-3
GO:0043088	regulation of Cdc42 GTPase activity	7.874755e-3
GO:0021696	cerebellar cortex morphogenesis	7.960085e-3
GO:0021702	cerebellar Purkinje cell differentiation	7.996299e-3
GO:0046637	regulation of alpha-beta T cell differentiation	8.023655e-3
GO:0016202	regulation of striated muscle tissue development	8.094004e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	8.134921e-3
GO:0019048	virus-host interaction	8.193356e-3
GO:0002663	positive regulation of B cell tolerance induction	8.251104e-3
GO:0061198	fungiform papilla formation	8.251104e-3
GO:0006829	zinc ion transport	8.273383e-3
GO:0045109	intermediate filament organization	8.293829e-3
GO:0051057	positive regulation of small GTPase mediated signal transduction	8.351210e-3
GO:0001935	endothelial cell proliferation	8.372342e-3
GO:0001732	formation of translation initiation complex	8.376728e-3
GO:0034330	cell junction organization	8.379414e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	8.386851e-3
GO:0043931	ossification involved in bone maturation	8.457229e-3
GO:0006044	N-acetylglucosamine metabolic process	8.501323e-3
GO:0030500	regulation of bone mineralization	8.529842e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	8.628947e-3
GO:0006198	cAMP catabolic process	8.704832e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	8.705182e-3
GO:0055017	cardiac muscle tissue growth	8.732483e-3
GO:0034655	nucleobase-containing compound catabolic process	8.738963e-3
GO:0046668	regulation of retinal cell programmed cell death	8.814924e-3
GO:0014047	glutamate secretion	8.814924e-3
GO:0071624	positive regulation of granulocyte chemotaxis	8.875989e-3
GO:0070535	histone H2A K63-linked ubiquitination	8.875989e-3
GO:0090104	pancreatic E cell differentiation	8.875989e-3
GO:0031860	telomeric 3' overhang formation	8.875989e-3
GO:0003311	pancreatic D cell differentiation	8.875989e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	8.875989e-3
GO:0010463	mesenchymal cell proliferation	9.007656e-3
GO:2001020	regulation of response to DNA damage stimulus	9.180303e-3
GO:0006705	mineralocorticoid biosynthetic process	9.208378e-3
GO:0048210	Golgi vesicle fusion to target membrane	9.284829e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	9.323182e-3
GO:0006882	cellular zinc ion homeostasis	9.323182e-3
GO:2000425	regulation of apoptotic cell clearance	9.521716e-3
GO:0043691	reverse cholesterol transport	9.553040e-3
GO:0032026	response to magnesium ion	9.590503e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	9.590503e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	9.707260e-3
GO:0043154	negative regulation of caspase activity	9.719619e-3
GO:0046666	retinal cell programmed cell death	9.839391e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	9.839391e-3
GO:0022616	DNA strand elongation	9.839391e-3
GO:0035356	cellular triglyceride homeostasis	9.965229e-3
GO:0019464	glycine decarboxylation via glycine cleavage system	9.965229e-3
GO:0060699	regulation of endoribonuclease activity	9.965229e-3
GO:0000055	ribosomal large subunit export from nucleus	9.965229e-3
GO:0000056	ribosomal small subunit export from nucleus	9.965229e-3
GO:0006348	chromatin silencing at telomere	9.965229e-3
GO:0045104	intermediate filament cytoskeleton organization	9.970450e-3
GO:0045815	positive regulation of gene expression, epigenetic	9.973742e-3
GO:0050778	positive regulation of immune response	1.016734e-2
GO:0007008	outer mitochondrial membrane organization	1.021791e-2
GO:0008633	activation of pro-apoptotic gene products	1.024693e-2
GO:0035404	histone-serine phosphorylation	1.045547e-2
GO:0032873	negative regulation of stress-activated MAPK cascade	1.045547e-2
GO:0061370	testosterone biosynthetic process	1.047157e-2
GO:0009648	photoperiodism	1.047157e-2
GO:0006942	regulation of striated muscle contraction	1.048092e-2
GO:0042074	cell migration involved in gastrulation	1.049682e-2
GO:0051279	regulation of release of sequestered calcium ion into cytosol	1.054955e-2
GO:0045071	negative regulation of viral genome replication	1.056481e-2
GO:0061044	negative regulation of vascular wound healing	1.062836e-2
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	1.062836e-2
GO:0071258	cellular response to gravity	1.062836e-2