Novel motif:164

name:	motif164_AGCCGATTTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0003279	cardiac septum development	2.508683e-10
GO:0060976	coronary vasculature development	3.824331e-10
GO:0048627	myoblast development	1.161339e-9
GO:0045046	protein import into peroxisome membrane	1.541828e-9
GO:0060764	cell-cell signaling involved in mammary gland development	3.275034e-9
GO:0022417	protein maturation by protein folding	7.239741e-9
GO:0060535	trachea cartilage morphogenesis	3.311005e-8
GO:0051891	positive regulation of cardioblast differentiation	4.215905e-8
GO:0060534	trachea cartilage development	6.165397e-8
GO:0003281	ventricular septum development	8.225695e-8
GO:0006625	protein targeting to peroxisome	1.205153e-7
GO:0043574	peroxisomal transport	1.997908e-7
GO:0002502	peptide antigen assembly with MHC class I protein complex	4.010100e-7
GO:0060009	Sertoli cell development	6.634051e-7
GO:0007320	insemination	8.339717e-7
GO:0003166	bundle of His development	1.107806e-6
GO:0003148	outflow tract septum morphogenesis	1.220059e-6
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	1.471705e-6
GO:0007620	copulation	1.664516e-6
GO:0003184	pulmonary valve morphogenesis	1.690299e-6
GO:0016557	peroxisome membrane biogenesis	1.773084e-6
GO:0048488	synaptic vesicle endocytosis	1.819670e-6
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.180647e-6
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.180647e-6
GO:0015747	urate transport	2.180647e-6
GO:0030573	bile acid catabolic process	2.786097e-6
GO:2000505	regulation of energy homeostasis	3.026428e-6
GO:0051204	protein insertion into mitochondrial membrane	5.340264e-6
GO:0003161	cardiac conduction system development	5.508471e-6
GO:0051457	maintenance of protein location in nucleus	6.739770e-6
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	9.105091e-6
GO:0060037	pharyngeal system development	9.908842e-6
GO:0001562	response to protozoan	1.064951e-5
GO:0003218	cardiac left ventricle formation	1.141876e-5
GO:0021523	somatic motor neuron differentiation	1.158514e-5
GO:0090394	negative regulation of excitatory postsynaptic membrane potential	1.367253e-5
GO:0000414	regulation of histone H3-K36 methylation	1.488989e-5
GO:0048199	vesicle targeting, to, from or within Golgi	1.509446e-5
GO:0061143	alveolar primary septum development	1.579203e-5
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	1.737413e-5
GO:0007340	acrosome reaction	2.085349e-5
GO:0060480	lung goblet cell differentiation	2.105858e-5
GO:0042832	defense response to protozoan	2.211611e-5
GO:0032864	activation of Cdc42 GTPase activity	2.218909e-5
GO:0009052	pentose-phosphate shunt, non-oxidative branch	2.438856e-5
GO:0045837	negative regulation of membrane potential	3.270570e-5
GO:0006287	base-excision repair, gap-filling	3.472849e-5
GO:0021506	anterior neuropore closure	3.519435e-5
GO:0045686	negative regulation of glial cell differentiation	3.527172e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.779627e-5
GO:0019987	negative regulation of anti-apoptosis	5.272707e-5
GO:0010842	retina layer formation	5.303981e-5
GO:2000378	negative regulation of reactive oxygen species metabolic process	5.918169e-5
GO:0070344	regulation of fat cell proliferation	6.107003e-5
GO:0090086	negative regulation of protein deubiquitination	6.309341e-5
GO:0060482	lobar bronchus development	6.519407e-5
GO:0043097	pyrimidine nucleoside salvage	6.604401e-5
GO:0007031	peroxisome organization	6.986355e-5
GO:0033364	mast cell secretory granule organization	6.990117e-5
GO:0071109	superior temporal gyrus development	7.102431e-5
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	7.377948e-5
GO:0007099	centriole replication	7.522006e-5
GO:0021675	nerve development	7.691786e-5
GO:0061034	olfactory bulb mitral cell layer development	8.341585e-5
GO:0002553	histamine secretion by mast cell	8.898821e-5
GO:0070670	response to interleukin-4	8.990364e-5
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	9.943157e-5
GO:2000253	positive regulation of feeding behavior	1.074390e-4
GO:2000507	positive regulation of energy homeostasis	1.074390e-4
GO:0006654	phosphatidic acid biosynthetic process	1.078594e-4
GO:0051788	response to misfolded protein	1.302753e-4
GO:0007269	neurotransmitter secretion	1.339958e-4
GO:0042423	catecholamine biosynthetic process	1.409303e-4
GO:0048291	isotype switching to IgG isotypes	1.426542e-4
GO:0090324	negative regulation of oxidative phosphorylation	1.426542e-4
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.426542e-4
GO:0010255	glucose mediated signaling pathway	1.426542e-4
GO:0002368	B cell cytokine production	1.426542e-4
GO:0042178	xenobiotic catabolic process	1.431831e-4
GO:0010498	proteasomal protein catabolic process	1.436170e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	1.565515e-4
GO:0009301	snRNA transcription	1.567777e-4
GO:0045116	protein neddylation	1.573393e-4
GO:0043174	nucleoside salvage	1.578309e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.650125e-4
GO:0043303	mast cell degranulation	1.753629e-4
GO:0002021	response to dietary excess	1.763053e-4
GO:0060576	intestinal epithelial cell development	1.764593e-4
GO:0031129	inductive cell-cell signaling	1.838440e-4
GO:0061136	regulation of proteasomal protein catabolic process	1.907146e-4
GO:0061180	mammary gland epithelium development	1.964975e-4
GO:0060008	Sertoli cell differentiation	1.983889e-4
GO:0051890	regulation of cardioblast differentiation	2.063054e-4
GO:0045070	positive regulation of viral genome replication	2.102480e-4
GO:0060574	intestinal epithelial cell maturation	2.164493e-4
GO:0009637	response to blue light	2.166339e-4
GO:0048755	branching morphogenesis of a nerve	2.181179e-4
GO:0034214	protein hexamerization	2.183401e-4
GO:0072092	ureteric bud invasion	2.269215e-4
GO:0060732	positive regulation of inositol phosphate biosynthetic process	2.269215e-4
GO:0009785	blue light signaling pathway	2.276429e-4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	2.282764e-4
GO:0014014	negative regulation of gliogenesis	2.290986e-4
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	2.336725e-4
GO:0021623	oculomotor nerve formation	2.336725e-4
GO:0003409	optic cup structural organization	2.336725e-4
GO:0003404	optic vesicle morphogenesis	2.336725e-4
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	2.363598e-4
GO:0001824	blastocyst development	2.449840e-4
GO:0003168	cardiac Purkinje fiber cell differentiation	2.509344e-4
GO:0060928	atrioventricular node cell development	2.509344e-4
GO:0060929	atrioventricular node cell fate commitment	2.509344e-4
GO:0003342	proepicardium development	2.509344e-4
GO:2000009	negative regulation of protein localization at cell surface	2.541039e-4
GO:0070170	regulation of tooth mineralization	2.642062e-4
GO:0033363	secretory granule organization	2.682659e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	2.811317e-4
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.952262e-4
GO:0072267	metanephric capsule specification	3.189982e-4
GO:0000416	positive regulation of histone H3-K36 methylation	3.208303e-4
GO:0048203	vesicle targeting, trans-Golgi to endosome	3.289104e-4
GO:0060980	cell migration involved in coronary vasculogenesis	3.323381e-4
GO:0035470	positive regulation of vascular wound healing	3.323381e-4
GO:0050881	musculoskeletal movement	3.368518e-4
GO:0060052	neurofilament cytoskeleton organization	3.444316e-4
GO:0055014	atrial cardiac muscle cell development	3.473524e-4
GO:2000824	negative regulation of androgen receptor activity	3.495786e-4
GO:0035136	forelimb morphogenesis	3.640851e-4
GO:0006545	glycine biosynthetic process	3.761463e-4
GO:0035646	endosome to melanosome transport	3.780920e-4
GO:0032581	ER-dependent peroxisome organization	3.780920e-4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	3.787014e-4
GO:0048194	Golgi vesicle budding	3.853510e-4
GO:0033211	adiponectin-mediated signaling pathway	3.883292e-4
GO:0042761	very long-chain fatty acid biosynthetic process	3.933188e-4
GO:0031398	positive regulation of protein ubiquitination	4.124690e-4
GO:0007270	neuron-neuron synaptic transmission	4.246709e-4
GO:0060677	ureteric bud elongation	4.569269e-4
GO:0003205	cardiac chamber development	4.601951e-4
GO:0060411	cardiac septum morphogenesis	4.680236e-4
GO:0016082	synaptic vesicle priming	4.774178e-4
GO:0060575	intestinal epithelial cell differentiation	4.832913e-4
GO:0021603	cranial nerve formation	5.394486e-4
GO:0060435	bronchiole development	5.511837e-4
GO:0002536	respiratory burst involved in inflammatory response	5.614678e-4
GO:0072093	metanephric renal vesicle formation	5.683830e-4
GO:0060161	positive regulation of dopamine receptor signaling pathway	5.782222e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	5.917485e-4
GO:0046600	negative regulation of centriole replication	6.123584e-4
GO:0010735	positive regulation of transcription via serum response element binding	6.123584e-4
GO:0021772	olfactory bulb development	6.203473e-4
GO:0042136	neurotransmitter biosynthetic process	6.271723e-4
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	6.561172e-4
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	6.833886e-4
GO:0045792	negative regulation of cell size	7.067359e-4
GO:0051932	synaptic transmission, GABAergic	7.170366e-4
GO:0016191	synaptic vesicle uncoating	7.170366e-4
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.170366e-4
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.170366e-4
GO:0090303	positive regulation of wound healing	7.444470e-4
GO:0021522	spinal cord motor neuron differentiation	7.574936e-4
GO:0021545	cranial nerve development	7.579266e-4
GO:0006983	ER overload response	7.764958e-4
GO:0071625	vocalization behavior	8.323598e-4
GO:0002082	regulation of oxidative phosphorylation	8.354026e-4
GO:0046487	glyoxylate metabolic process	8.413188e-4
GO:0071281	cellular response to iron ion	8.513663e-4
GO:0072171	mesonephric tubule morphogenesis	8.552135e-4
GO:0000236	mitotic prometaphase	8.982286e-4
GO:0045008	depyrimidination	9.090991e-4
GO:0005993	trehalose catabolic process	9.172224e-4
GO:0014061	regulation of norepinephrine secretion	9.303285e-4
GO:0043267	negative regulation of potassium ion transport	9.668387e-4
GO:0046724	oxalic acid secretion	9.934856e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	9.934856e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	9.934856e-4
GO:0038007	netrin-activated signaling pathway	1.018437e-3
GO:0016926	protein desumoylation	1.026433e-3
GO:0003009	skeletal muscle contraction	1.045539e-3
GO:0030262	apoptotic nuclear change	1.047016e-3
GO:0032836	glomerular basement membrane development	1.061327e-3
GO:0021557	oculomotor nerve development	1.061327e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.068424e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	1.100581e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.148160e-3
GO:0060606	tube closure	1.240320e-3
GO:0009106	lipoate metabolic process	1.242527e-3
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	1.252093e-3
GO:0044091	membrane biogenesis	1.293402e-3
GO:0035966	response to topologically incorrect protein	1.326195e-3
GO:0071353	cellular response to interleukin-4	1.326417e-3
GO:0035854	eosinophil fate commitment	1.359640e-3
GO:0030222	eosinophil differentiation	1.359640e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	1.375693e-3
GO:0042908	xenobiotic transport	1.376255e-3
GO:0061029	eyelid development in camera-type eye	1.409863e-3
GO:0090085	regulation of protein deubiquitination	1.446138e-3
GO:0070345	negative regulation of fat cell proliferation	1.446138e-3
GO:0060611	mammary gland fat development	1.446138e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	1.454096e-3
GO:2000096	positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway	1.478041e-3
GO:0006437	tyrosyl-tRNA aminoacylation	1.479722e-3
GO:0006244	pyrimidine nucleotide catabolic process	1.503972e-3
GO:0046949	fatty-acyl-CoA biosynthetic process	1.524902e-3
GO:0060816	random inactivation of X chromosome	1.556708e-3
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	1.556708e-3
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	1.556708e-3
GO:0032738	positive regulation of interleukin-15 production	1.556708e-3
GO:0009236	cobalamin biosynthetic process	1.556708e-3
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	1.578087e-3
GO:0019693	ribose phosphate metabolic process	1.672813e-3
GO:0001921	positive regulation of receptor recycling	1.684729e-3
GO:0001843	neural tube closure	1.704900e-3
GO:0001675	acrosome assembly	1.711135e-3
GO:0043241	protein complex disassembly	1.732878e-3
GO:0009125	nucleoside monophosphate catabolic process	1.772945e-3
GO:0061015	snRNA import into nucleus	1.864661e-3
GO:0006756	AMP phosphorylation	1.864661e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	1.867126e-3
GO:0045342	MHC class II biosynthetic process	1.877042e-3
GO:0070839	divalent metal ion export	1.877042e-3
GO:0043091	L-arginine import	1.877042e-3
GO:0035511	oxidative DNA demethylation	1.877042e-3
GO:0015707	nitrite transport	1.877042e-3
GO:0032632	interleukin-3 production	1.877042e-3
GO:0006876	cellular cadmium ion homeostasis	1.877042e-3
GO:0007020	microtubule nucleation	1.883218e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.024917e-3
GO:0007618	mating	2.065704e-3
GO:0010070	zygote asymmetric cell division	2.068980e-3
GO:0033598	mammary gland epithelial cell proliferation	2.083666e-3
GO:0042942	D-serine transport	2.092510e-3
GO:0016056	rhodopsin mediated signaling pathway	2.143540e-3
GO:0006600	creatine metabolic process	2.163691e-3
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	2.180331e-3
GO:0060971	embryonic heart tube left/right pattern formation	2.214338e-3
GO:0060920	pacemaker cell differentiation	2.214338e-3
GO:0003231	cardiac ventricle development	2.227906e-3
GO:0048680	positive regulation of axon regeneration	2.228804e-3
GO:0001839	neural plate morphogenesis	2.240042e-3
GO:0009107	lipoate biosynthetic process	2.251209e-3
GO:0009262	deoxyribonucleotide metabolic process	2.260495e-3
GO:0048205	COPI coating of Golgi vesicle	2.281280e-3
GO:0071359	cellular response to dsRNA	2.297795e-3
GO:0006476	protein deacetylation	2.297795e-3
GO:0035601	protein deacylation	2.386938e-3
GO:0030497	fatty acid elongation	2.389431e-3
GO:0000038	very long-chain fatty acid metabolic process	2.412869e-3
GO:0043010	camera-type eye development	2.413702e-3
GO:0001825	blastocyst formation	2.415958e-3
GO:0051569	regulation of histone H3-K4 methylation	2.423008e-3
GO:0071218	cellular response to misfolded protein	2.482785e-3
GO:0070845	polyubiquitinated misfolded protein transport	2.503585e-3
GO:0043088	regulation of Cdc42 GTPase activity	2.532887e-3
GO:0007549	dosage compensation	2.540137e-3
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	2.561772e-3
GO:0048710	regulation of astrocyte differentiation	2.611209e-3
GO:0030513	positive regulation of BMP signaling pathway	2.629714e-3
GO:0048541	Peyer's patch development	2.662697e-3
GO:0060977	coronary vasculature morphogenesis	2.701877e-3
GO:0043331	response to dsRNA	2.709909e-3
GO:0003283	atrial septum development	2.725581e-3
GO:0001702	gastrulation with mouth forming second	2.754608e-3
GO:0023061	signal release	2.765548e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	2.827862e-3
GO:0003222	ventricular trabecular myocardium morphogenesis	2.827862e-3
GO:0002003	angiotensin maturation	2.827862e-3
GO:0045649	regulation of macrophage differentiation	2.872628e-3
GO:0009589	detection of UV	2.874623e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	2.874623e-3
GO:0010826	negative regulation of centrosome duplication	2.874623e-3
GO:0006235	dTTP biosynthetic process	2.874623e-3
GO:0006550	isoleucine catabolic process	2.874623e-3
GO:0009098	leucine biosynthetic process	2.874623e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	2.902798e-3
GO:0060437	lung growth	2.914009e-3
GO:0043624	cellular protein complex disassembly	2.927160e-3
GO:0002448	mast cell mediated immunity	2.933726e-3
GO:0032909	regulation of transforming growth factor beta2 production	2.950304e-3
GO:0031557	induction of programmed cell death in response to chemical stimulus	2.969394e-3
GO:0048260	positive regulation of receptor-mediated endocytosis	3.041274e-3
GO:0001833	inner cell mass cell proliferation	3.058443e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.211447e-3
GO:0042473	outer ear morphogenesis	3.212694e-3
GO:0034346	positive regulation of type III interferon production	3.284795e-3
GO:0043092	L-amino acid import	3.304717e-3
GO:0003360	brainstem development	3.305730e-3
GO:0008589	regulation of smoothened signaling pathway	3.393906e-3
GO:0014020	primary neural tube formation	3.446915e-3
GO:0046473	phosphatidic acid metabolic process	3.460641e-3
GO:0006689	ganglioside catabolic process	3.521049e-3
GO:0051568	histone H3-K4 methylation	3.524009e-3
GO:0048537	mucosal-associated lymphoid tissue development	3.538817e-3
GO:0060039	pericardium development	3.641030e-3
GO:0006835	dicarboxylic acid transport	3.716251e-3
GO:0030047	actin modification	3.722873e-3
GO:0018916	nitrobenzene metabolic process	3.722873e-3
GO:0035552	oxidative single-stranded DNA demethylation	3.793323e-3
GO:0046108	uridine metabolic process	3.793323e-3
GO:0035039	male pronucleus assembly	3.795657e-3
GO:0032984	macromolecular complex disassembly	3.832291e-3
GO:0090009	primitive streak formation	3.835078e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	3.841011e-3
GO:0034198	cellular response to amino acid starvation	3.841011e-3
GO:0051445	regulation of meiotic cell cycle	3.884518e-3
GO:0009109	coenzyme catabolic process	3.947128e-3
GO:0006288	base-excision repair, DNA ligation	3.955966e-3
GO:0003285	septum secundum development	3.955966e-3
GO:0016575	histone deacetylation	3.960532e-3
GO:0042472	inner ear morphogenesis	3.961407e-3
GO:0051208	sequestering of calcium ion	3.969402e-3
GO:0009313	oligosaccharide catabolic process	4.059532e-3
GO:0006695	cholesterol biosynthetic process	4.092631e-3
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	4.161917e-3
GO:0046079	dUMP catabolic process	4.161917e-3
GO:0031860	telomeric 3' overhang formation	4.161917e-3
GO:2000737	negative regulation of stem cell differentiation	4.203781e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	4.279228e-3
GO:0031427	response to methotrexate	4.279228e-3
GO:2000077	negative regulation of type B pancreatic cell development	4.285708e-3
GO:0071166	ribonucleoprotein complex localization	4.285708e-3
GO:0048711	positive regulation of astrocyte differentiation	4.289591e-3
GO:0014029	neural crest formation	4.311972e-3
GO:0060744	mammary gland branching involved in thelarche	4.399380e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	4.490085e-3
GO:0001829	trophectodermal cell differentiation	4.539302e-3
GO:0005984	disaccharide metabolic process	4.544097e-3
GO:0021903	rostrocaudal neural tube patterning	4.560222e-3
GO:0051572	negative regulation of histone H3-K4 methylation	4.645107e-3
GO:0010807	regulation of synaptic vesicle priming	4.645107e-3
GO:0021889	olfactory bulb interneuron differentiation	4.665288e-3
GO:0009264	deoxyribonucleotide catabolic process	4.695740e-3
GO:0060379	cardiac muscle cell myoblast differentiation	4.706271e-3
GO:0003105	negative regulation of glomerular filtration	4.706271e-3
GO:0002017	regulation of blood volume by renal aldosterone	4.706271e-3
GO:0050918	positive chemotaxis	4.714932e-3
GO:0060923	cardiac muscle cell fate commitment	4.779742e-3
GO:0060070	canonical Wnt receptor signaling pathway	4.861955e-3
GO:0070926	regulation of ATP:ADP antiporter activity	4.928128e-3
GO:0009231	riboflavin biosynthetic process	4.928128e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	4.939827e-3
GO:0032808	lacrimal gland development	4.955021e-3
GO:0019532	oxalate transport	5.047852e-3
GO:2000178	negative regulation of neural precursor cell proliferation	5.170583e-3
GO:0060644	mammary gland epithelial cell differentiation	5.201946e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	5.247303e-3
GO:0040020	regulation of meiosis	5.312868e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	5.358408e-3
GO:0003215	cardiac right ventricle morphogenesis	5.403541e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	5.412759e-3
GO:0045650	negative regulation of macrophage differentiation	5.426217e-3
GO:0060043	regulation of cardiac muscle cell proliferation	5.441751e-3
GO:0017156	calcium ion-dependent exocytosis	5.484801e-3
GO:0016558	protein import into peroxisome matrix	5.510224e-3
GO:0090102	cochlea development	5.559976e-3
GO:0032007	negative regulation of TOR signaling cascade	5.578615e-3
GO:0006196	AMP catabolic process	5.689425e-3
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	5.689425e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	5.769525e-3
GO:0060603	mammary gland duct morphogenesis	5.827085e-3
GO:0001505	regulation of neurotransmitter levels	5.852847e-3
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	5.894043e-3
GO:0043491	protein kinase B signaling cascade	5.912708e-3
GO:0060484	lung-associated mesenchyme development	5.915499e-3
GO:0060065	uterus development	5.925593e-3
GO:0055021	regulation of cardiac muscle tissue growth	5.995623e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	6.047781e-3
GO:0035115	embryonic forelimb morphogenesis	6.061211e-3
GO:0034623	cellular macromolecular complex disassembly	6.061804e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.066252e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	6.157101e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	6.161091e-3
GO:0060749	mammary gland alveolus development	6.193214e-3
GO:0008054	cyclin catabolic process	6.214781e-3
GO:0034109	homotypic cell-cell adhesion	6.232896e-3
GO:0043266	regulation of potassium ion transport	6.360859e-3
GO:0072178	nephric duct morphogenesis	6.395903e-3
GO:2000020	positive regulation of male gonad development	6.423419e-3
GO:0019227	neuronal action potential propagation	6.435805e-3
GO:0048691	positive regulation of axon extension involved in regeneration	6.519868e-3
GO:0050689	negative regulation of defense response to virus by host	6.519868e-3
GO:0019056	modulation by virus of host transcription	6.519868e-3
GO:0046618	drug export	6.610342e-3
GO:0006742	NADP catabolic process	6.610342e-3
GO:0015858	nucleoside transport	6.710520e-3
GO:0021954	central nervous system neuron development	6.741083e-3
GO:0051103	DNA ligation involved in DNA repair	6.829354e-3
GO:0060159	regulation of dopamine receptor signaling pathway	6.866748e-3
GO:0002002	regulation of angiotensin levels in blood	6.883641e-3
GO:0071482	cellular response to light stimulus	6.951760e-3
GO:0003056	regulation of vascular smooth muscle contraction	6.974837e-3
GO:0000415	negative regulation of histone H3-K36 methylation	7.135041e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	7.144278e-3
GO:0021526	medial motor column neuron differentiation	7.205818e-3
GO:0002309	T cell proliferation involved in immune response	7.205818e-3
GO:0072321	chaperone-mediated protein transport	7.222154e-3
GO:0048712	negative regulation of astrocyte differentiation	7.235895e-3
GO:0021683	cerebellar granular layer morphogenesis	7.295678e-3
GO:0034111	negative regulation of homotypic cell-cell adhesion	7.396792e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	7.452600e-3
GO:0006836	neurotransmitter transport	7.514962e-3
GO:0006538	glutamate catabolic process	7.605548e-3
GO:0046086	adenosine biosynthetic process	7.619797e-3
GO:0032049	cardiolipin biosynthetic process	7.619797e-3
GO:0031296	B cell costimulation	7.619797e-3
GO:0060177	regulation of angiotensin metabolic process	7.641025e-3
GO:0018022	peptidyl-lysine methylation	7.641025e-3
GO:0060384	innervation	7.802995e-3
GO:0010919	regulation of inositol phosphate biosynthetic process	7.802995e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	7.806810e-3
GO:0003407	neural retina development	7.885793e-3
GO:0060648	mammary gland bud morphogenesis	7.937116e-3
GO:0048596	embryonic camera-type eye morphogenesis	8.021152e-3
GO:0018298	protein-chromophore linkage	8.054745e-3
GO:0045646	regulation of erythrocyte differentiation	8.064162e-3
GO:0051016	barbed-end actin filament capping	8.171975e-3
GO:0045161	neuronal ion channel clustering	8.177806e-3
GO:0022412	cellular process involved in reproduction in multicellular organism	8.229236e-3
GO:0048048	embryonic eye morphogenesis	8.291457e-3
GO:0061338	atrioventricular node impulse conduction delay	8.305358e-3
GO:0045078	positive regulation of interferon-gamma biosynthetic process	8.340135e-3
GO:0002367	cytokine production involved in immune response	8.340135e-3
GO:0042471	ear morphogenesis	8.378014e-3
GO:0071360	cellular response to exogenous dsRNA	8.408969e-3
GO:0019264	glycine biosynthetic process from serine	8.559024e-3
GO:0051793	medium-chain fatty acid catabolic process	8.659930e-3
GO:0008049	male courtship behavior	8.659930e-3
GO:0006540	glutamate decarboxylation to succinate	8.668810e-3
GO:0030422	production of siRNA involved in RNA interference	8.668810e-3
GO:0002275	myeloid cell activation involved in immune response	8.673980e-3
GO:0042297	vocal learning	8.791309e-3
GO:0035441	cell migration involved in vasculogenesis	8.791309e-3
GO:0050432	catecholamine secretion	8.875512e-3
GO:0031076	embryonic camera-type eye development	8.880470e-3
GO:0006014	D-ribose metabolic process	9.094677e-3
GO:0051885	positive regulation of anagen	9.178092e-3
GO:2000381	negative regulation of mesoderm development	9.178092e-3
GO:0045992	negative regulation of embryonic development	9.178092e-3
GO:0021764	amygdala development	9.178092e-3
GO:0014835	myoblast cell differentiation involved in skeletal muscle regeneration	9.178092e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	9.178092e-3
GO:0007285	primary spermatocyte growth	9.178092e-3
GO:0072180	mesonephric duct morphogenesis	9.352594e-3
GO:0016050	vesicle organization	9.442908e-3
GO:0031647	regulation of protein stability	9.533087e-3
GO:0021884	forebrain neuron development	9.675071e-3
GO:0051612	negative regulation of serotonin uptake	9.695097e-3
GO:0045356	positive regulation of interferon-alpha biosynthetic process	9.720773e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	9.769224e-3
GO:0048384	retinoic acid receptor signaling pathway	9.784101e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	9.800838e-3
GO:0010838	positive regulation of keratinocyte proliferation	9.800838e-3
GO:0060900	embryonic camera-type eye formation	9.834992e-3
GO:0001821	histamine secretion	9.878695e-3
GO:0042727	flavin-containing compound biosynthetic process	9.964195e-3
GO:0045648	positive regulation of erythrocyte differentiation	1.001898e-2
GO:0007423	sensory organ development	1.019102e-2
GO:0046314	phosphocreatine biosynthetic process	1.019811e-2
GO:0009597	detection of virus	1.027951e-2
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.064802e-2
GO:0046501	protoporphyrinogen IX metabolic process	1.070755e-2
GO:0071104	response to interleukin-9	1.080219e-2
GO:0070682	proteasome regulatory particle assembly	1.080219e-2
GO:0046940	nucleoside monophosphate phosphorylation	1.080219e-2
GO:0009159	deoxyribonucleoside monophosphate catabolic process	1.080219e-2
GO:0060841	venous blood vessel development	1.090368e-2
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	1.092176e-2
GO:0032329	serine transport	1.116265e-2
GO:0014038	regulation of Schwann cell differentiation	1.116265e-2
GO:0051196	regulation of coenzyme metabolic process	1.136300e-2
GO:0045599	negative regulation of fat cell differentiation	1.149144e-2
GO:0050821	protein stabilization	1.153082e-2
GO:0048013	ephrin receptor signaling pathway	1.154813e-2
GO:0006637	acyl-CoA metabolic process	1.156018e-2
GO:0070172	positive regulation of tooth mineralization	1.164296e-2
GO:0060455	negative regulation of gastric acid secretion	1.166576e-2
GO:0050772	positive regulation of axonogenesis	1.186200e-2
GO:0003197	endocardial cushion development	1.201616e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.240644e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.255858e-2
GO:0045654	positive regulation of megakaryocyte differentiation	1.256035e-2
GO:0018026	peptidyl-lysine monomethylation	1.256035e-2
GO:0032790	ribosome disassembly	1.263301e-2
GO:0002532	production of molecular mediator involved in inflammatory response	1.266689e-2
GO:0072176	nephric duct development	1.269522e-2
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.289232e-2
GO:0015851	nucleobase transport	1.291912e-2
GO:0051187	cofactor catabolic process	1.306716e-2
GO:0046884	follicle-stimulating hormone secretion	1.306791e-2
GO:0032275	luteinizing hormone secretion	1.306791e-2
GO:0008156	negative regulation of DNA replication	1.307838e-2
GO:0043461	proton-transporting ATP synthase complex assembly	1.312829e-2
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.314699e-2
GO:0006612	protein targeting to membrane	1.341878e-2
GO:0006438	valyl-tRNA aminoacylation	1.354952e-2
GO:0006900	membrane budding	1.380455e-2
GO:0010675	regulation of cellular carbohydrate metabolic process	1.380498e-2
GO:0046605	regulation of centrosome cycle	1.385539e-2
GO:0003016	respiratory system process	1.394679e-2
GO:0061072	iris morphogenesis	1.409723e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0000910	cytokinesis	1.332286e-9
GO:0046015	regulation of transcription by glucose	7.631034e-9
GO:0090343	positive regulation of cell aging	1.073882e-8
GO:0023019	signal transduction involved in regulation of gene expression	5.996021e-8
GO:0033205	cell cycle cytokinesis	3.087939e-7
GO:0007076	mitotic chromosome condensation	3.799058e-7
GO:0034770	histone H4-K20 methylation	5.566640e-7
GO:0031398	positive regulation of protein ubiquitination	6.122504e-7
GO:0045014	negative regulation of transcription by glucose	7.451987e-7
GO:2000781	positive regulation of double-strand break repair	7.502391e-7
GO:0051532	regulation of NFAT protein import into nucleus	8.576142e-7
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.350839e-6
GO:0043966	histone H3 acetylation	1.641326e-6
GO:0007589	body fluid secretion	1.985698e-6
GO:0045647	negative regulation of erythrocyte differentiation	3.325194e-6
GO:0033629	negative regulation of cell adhesion mediated by integrin	3.536740e-6
GO:0051100	negative regulation of binding	3.742607e-6
GO:0090342	regulation of cell aging	3.867772e-6
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	5.067243e-6
GO:0043252	sodium-independent organic anion transport	5.626575e-6
GO:0048598	embryonic morphogenesis	6.206097e-6
GO:0010312	detoxification of zinc ion	6.574563e-6
GO:0003158	endothelium development	6.870970e-6
GO:0043117	positive regulation of vascular permeability	7.114737e-6
GO:0002309	T cell proliferation involved in immune response	7.867438e-6
GO:0010561	negative regulation of glycoprotein biosynthetic process	8.137308e-6
GO:0045446	endothelial cell differentiation	8.960263e-6
GO:0010107	potassium ion import	9.857728e-6
GO:0060051	negative regulation of protein glycosylation	1.014635e-5
GO:0000070	mitotic sister chromatid segregation	1.053518e-5
GO:0043507	positive regulation of JUN kinase activity	1.107865e-5
GO:0060319	primitive erythrocyte differentiation	1.110402e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.238138e-5
GO:0045994	positive regulation of translational initiation by iron	1.238138e-5
GO:0002037	negative regulation of L-glutamate transport	1.238138e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.238138e-5
GO:0071803	positive regulation of podosome assembly	1.576506e-5
GO:0006927	transformed cell apoptosis	1.658329e-5
GO:0001886	endothelial cell morphogenesis	2.270289e-5
GO:0071479	cellular response to ionizing radiation	2.338440e-5
GO:0090402	oncogene-induced senescence	2.603862e-5
GO:2000774	positive regulation of cellular senescence	2.603862e-5
GO:0035986	senescence-associated heterochromatin focus formation	2.603862e-5
GO:0000733	DNA strand renaturation	2.914093e-5
GO:0048630	skeletal muscle tissue growth	2.941437e-5
GO:0070302	regulation of stress-activated protein kinase signaling cascade	2.958406e-5
GO:0060049	regulation of protein glycosylation	3.009995e-5
GO:0045347	negative regulation of MHC class II biosynthetic process	3.009995e-5
GO:0002678	positive regulation of chronic inflammatory response	3.042321e-5
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3.079514e-5
GO:0090285	negative regulation of protein glycosylation in Golgi	3.109087e-5
GO:0006435	threonyl-tRNA aminoacylation	3.109087e-5
GO:0001841	neural tube formation	3.279029e-5
GO:0019047	provirus integration	3.488459e-5
GO:0031396	regulation of protein ubiquitination	3.594966e-5
GO:0000819	sister chromatid segregation	3.852408e-5
GO:0001843	neural tube closure	4.008822e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	4.018044e-5
GO:0031442	positive regulation of mRNA 3'-end processing	4.063937e-5
GO:0006359	regulation of transcription from RNA polymerase III promoter	4.063937e-5
GO:0016082	synaptic vesicle priming	4.841423e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	4.841423e-5
GO:0002575	basophil chemotaxis	5.165562e-5
GO:0051276	chromosome organization	5.254082e-5
GO:0060606	tube closure	5.739557e-5
GO:0043506	regulation of JUN kinase activity	6.912593e-5
GO:0014020	primary neural tube formation	7.272211e-5
GO:0006983	ER overload response	7.301903e-5
GO:0008608	attachment of spindle microtubules to kinetochore	8.168836e-5
GO:0046328	regulation of JNK cascade	8.373012e-5
GO:0045075	regulation of interleukin-12 biosynthetic process	8.442321e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	8.622682e-5
GO:0002227	innate immune response in mucosa	1.016898e-4
GO:0006351	transcription, DNA-dependent	1.167446e-4
GO:0003290	atrial septum secundum morphogenesis	1.194078e-4
GO:0016568	chromatin modification	1.201986e-4
GO:0046426	negative regulation of JAK-STAT cascade	1.221750e-4
GO:0009637	response to blue light	1.236333e-4
GO:0048011	nerve growth factor receptor signaling pathway	1.304191e-4
GO:0008343	adult feeding behavior	1.304191e-4
GO:0051101	regulation of DNA binding	1.350540e-4
GO:0051098	regulation of binding	1.375297e-4
GO:0021915	neural tube development	1.404413e-4
GO:0048034	heme O biosynthetic process	1.414157e-4
GO:0032774	RNA biosynthetic process	1.492252e-4
GO:0044070	regulation of anion transport	1.497812e-4
GO:0060555	induction of necroptosis by extracellular signals	1.519971e-4
GO:0055090	acylglycerol homeostasis	1.540657e-4
GO:0090403	oxidative stress-induced premature senescence	1.606237e-4
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.726486e-4
GO:0061013	regulation of mRNA catabolic process	1.852472e-4
GO:0090068	positive regulation of cell cycle process	1.866598e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	1.958096e-4
GO:0006982	response to lipid hydroperoxide	2.111675e-4
GO:2000772	regulation of cellular senescence	2.244213e-4
GO:0048227	plasma membrane to endosome transport	2.250390e-4
GO:2000352	negative regulation of endothelial cell apoptosis	2.279911e-4
GO:0016338	calcium-independent cell-cell adhesion	2.400666e-4
GO:0006325	chromatin organization	2.461528e-4
GO:0045083	negative regulation of interleukin-12 biosynthetic process	2.466817e-4
GO:0006479	protein methylation	2.468788e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	2.511762e-4
GO:0033132	negative regulation of glucokinase activity	2.632478e-4
GO:0090398	cellular senescence	2.822651e-4
GO:0022010	central nervous system myelination	2.877833e-4
GO:2000351	regulation of endothelial cell apoptosis	2.939317e-4
GO:2000677	regulation of transcription regulatory region DNA binding	3.068506e-4
GO:0030730	sequestering of triglyceride	3.152027e-4
GO:0015993	molecular hydrogen transport	3.164172e-4
GO:0051932	synaptic transmission, GABAergic	3.164172e-4
GO:0017148	negative regulation of translation	3.231759e-4
GO:0050685	positive regulation of mRNA processing	3.264838e-4
GO:0070625	zymogen granule exocytosis	3.287395e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	3.287395e-4
GO:0034259	negative regulation of Rho GTPase activity	3.287395e-4
GO:0031440	regulation of mRNA 3'-end processing	3.326581e-4
GO:0016070	RNA metabolic process	3.362047e-4
GO:0048702	embryonic neurocranium morphogenesis	3.362604e-4
GO:0010970	microtubule-based transport	3.461449e-4
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	3.462252e-4
GO:0043392	negative regulation of DNA binding	3.476310e-4
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	3.488293e-4
GO:0046512	sphingosine biosynthetic process	3.549120e-4
GO:0032095	regulation of response to food	3.621849e-4
GO:0060749	mammary gland alveolus development	3.674778e-4
GO:0001838	embryonic epithelial tube formation	3.700197e-4
GO:0032098	regulation of appetite	3.783151e-4
GO:0006970	response to osmotic stress	3.883173e-4
GO:0002036	regulation of L-glutamate transport	3.908439e-4
GO:0043405	regulation of MAP kinase activity	3.999683e-4
GO:0007254	JNK cascade	4.249520e-4
GO:0072175	epithelial tube formation	4.679970e-4
GO:0060480	lung goblet cell differentiation	4.723904e-4
GO:0008156	negative regulation of DNA replication	4.751718e-4
GO:0032715	negative regulation of interleukin-6 production	4.778731e-4
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4.796929e-4
GO:0000185	activation of MAPKKK activity	4.897386e-4
GO:0043114	regulation of vascular permeability	4.936316e-4
GO:0002532	production of molecular mediator involved in inflammatory response	5.081795e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	5.291270e-4
GO:2000971	negative regulation of detection of glucose	5.551031e-4
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	5.551031e-4
GO:0002536	respiratory burst involved in inflammatory response	5.551031e-4
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	5.551031e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	5.664790e-4
GO:0072520	seminiferous tubule development	5.664790e-4
GO:0033578	protein glycosylation in Golgi	5.664790e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	5.718505e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	5.718505e-4
GO:0045623	negative regulation of T-helper cell differentiation	5.718505e-4
GO:0000028	ribosomal small subunit assembly	5.763124e-4
GO:0010467	gene expression	5.863193e-4
GO:0034135	regulation of toll-like receptor 2 signaling pathway	6.142158e-4
GO:0035148	tube formation	6.194131e-4
GO:0031507	heterochromatin formation	6.215125e-4
GO:0007091	mitotic metaphase/anaphase transition	6.498197e-4
GO:0071900	regulation of protein serine/threonine kinase activity	6.571295e-4
GO:0001709	cell fate determination	7.156458e-4
GO:0051533	positive regulation of NFAT protein import into nucleus	7.311846e-4
GO:0045089	positive regulation of innate immune response	7.318905e-4
GO:0051313	attachment of spindle microtubules to chromosome	7.466974e-4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	7.468712e-4
GO:0043982	histone H4-K8 acetylation	7.478499e-4
GO:0043981	histone H4-K5 acetylation	7.478499e-4
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	7.677723e-4
GO:0001885	endothelial cell development	7.773466e-4
GO:0000060	protein import into nucleus, translocation	7.821362e-4
GO:0033590	response to cobalamin	7.880720e-4
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	7.880720e-4
GO:0045628	regulation of T-helper 2 cell differentiation	8.053379e-4
GO:0007595	lactation	8.181414e-4
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	8.222803e-4
GO:0061088	regulation of sequestering of zinc ion	8.521809e-4
GO:0023021	termination of signal transduction	8.680406e-4
GO:0016331	morphogenesis of embryonic epithelium	8.905476e-4
GO:0061046	regulation of branching involved in lung morphogenesis	9.068788e-4
GO:0021542	dentate gyrus development	9.455476e-4
GO:0016573	histone acetylation	9.859902e-4
GO:0043243	positive regulation of protein complex disassembly	9.935182e-4
GO:0022007	convergent extension involved in neural plate elongation	9.938640e-4
GO:0006105	succinate metabolic process	9.955772e-4
GO:0010940	positive regulation of necrotic cell death	1.049991e-3
GO:0090045	positive regulation of deacetylase activity	1.087016e-3
GO:0042149	cellular response to glucose starvation	1.130327e-3
GO:2000348	regulation of CD40 signaling pathway	1.132187e-3
GO:0016322	neuron remodeling	1.157570e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.213780e-3
GO:0007179	transforming growth factor beta receptor signaling pathway	1.221845e-3
GO:0030513	positive regulation of BMP signaling pathway	1.263776e-3
GO:0032289	central nervous system myelin formation	1.279219e-3
GO:0006477	protein sulfation	1.280173e-3
GO:0051798	positive regulation of hair follicle development	1.280173e-3
GO:0002676	regulation of chronic inflammatory response	1.283259e-3
GO:0032481	positive regulation of type I interferon production	1.323267e-3
GO:0042304	regulation of fatty acid biosynthetic process	1.336616e-3
GO:0045922	negative regulation of fatty acid metabolic process	1.347683e-3
GO:0070265	necrotic cell death	1.370726e-3
GO:0046514	ceramide catabolic process	1.380163e-3
GO:0060613	fat pad development	1.381216e-3
GO:0072230	metanephric proximal straight tubule development	1.413305e-3
GO:0072232	metanephric proximal convoluted tubule segment 2 development	1.413305e-3
GO:0090107	regulation of high-density lipoprotein particle assembly	1.413305e-3
GO:0072220	metanephric descending thin limb development	1.413305e-3
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	1.413305e-3
GO:0018872	arsonoacetate metabolic process	1.413305e-3
GO:0009446	putrescine biosynthetic process	1.413305e-3
GO:0035377	transepithelial water transport	1.413305e-3
GO:0035378	carbon dioxide transmembrane transport	1.413305e-3
GO:0071105	response to interleukin-11	1.413305e-3
GO:0051458	corticotropin secretion	1.413305e-3
GO:0060574	intestinal epithelial cell maturation	1.421937e-3
GO:0009651	response to salt stress	1.471873e-3
GO:0030854	positive regulation of granulocyte differentiation	1.487046e-3
GO:0051956	negative regulation of amino acid transport	1.490502e-3
GO:0048525	negative regulation of viral reproduction	1.561584e-3
GO:0007059	chromosome segregation	1.583725e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	1.661745e-3
GO:0045581	negative regulation of T cell differentiation	1.662939e-3
GO:0045475	locomotor rhythm	1.675118e-3
GO:0043983	histone H4-K12 acetylation	1.675118e-3
GO:0034453	microtubule anchoring	1.682567e-3
GO:0010452	histone H3-K36 methylation	1.697350e-3
GO:0003285	septum secundum development	1.755759e-3
GO:0032728	positive regulation of interferon-beta production	1.772986e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.854491e-3
GO:0090074	negative regulation of protein homodimerization activity	1.854491e-3
GO:0000414	regulation of histone H3-K36 methylation	1.854491e-3
GO:0042035	regulation of cytokine biosynthetic process	1.883306e-3
GO:0051923	sulfation	1.887977e-3
GO:0014842	regulation of satellite cell proliferation	1.912776e-3
GO:0021779	oligodendrocyte cell fate commitment	1.918787e-3
GO:0042088	T-helper 1 type immune response	1.943160e-3
GO:0002763	positive regulation of myeloid leukocyte differentiation	1.966077e-3
GO:0061014	positive regulation of mRNA catabolic process	2.003709e-3
GO:0051301	cell division	2.005216e-3
GO:0048935	peripheral nervous system neuron development	2.012548e-3
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	2.021544e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	2.088711e-3
GO:0006306	DNA methylation	2.098284e-3
GO:0031098	stress-activated protein kinase signaling cascade	2.221513e-3
GO:0050748	negative regulation of lipoprotein metabolic process	2.228628e-3
GO:0003382	epithelial cell morphogenesis	2.230213e-3
GO:0043406	positive regulation of MAP kinase activity	2.263461e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	2.340221e-3
GO:0006491	N-glycan processing	2.340221e-3
GO:0010637	negative regulation of mitochondrial fusion	2.372638e-3
GO:0071279	cellular response to cobalt ion	2.372638e-3
GO:0051005	negative regulation of lipoprotein lipase activity	2.375549e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	2.386174e-3
GO:0042036	negative regulation of cytokine biosynthetic process	2.397050e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	2.408642e-3
GO:0035767	endothelial cell chemotaxis	2.422731e-3
GO:0007080	mitotic metaphase plate congression	2.422731e-3
GO:0060482	lobar bronchus development	2.443917e-3
GO:0035330	regulation of hippo signaling cascade	2.496168e-3
GO:0032602	chemokine production	2.523412e-3
GO:0021935	cerebellar granule cell precursor tangential migration	2.523412e-3
GO:0030185	nitric oxide transport	2.523412e-3
GO:0034379	very-low-density lipoprotein particle assembly	2.530323e-3
GO:0000303	response to superoxide	2.568203e-3
GO:0010626	negative regulation of Schwann cell proliferation	2.618965e-3
GO:0065001	specification of axis polarity	2.618965e-3
GO:0070318	positive regulation of G0 to G1 transition	2.618965e-3
GO:0051594	detection of glucose	2.618965e-3
GO:0045620	negative regulation of lymphocyte differentiation	2.630854e-3
GO:0045732	positive regulation of protein catabolic process	2.659950e-3
GO:0051246	regulation of protein metabolic process	2.673367e-3
GO:0045071	negative regulation of viral genome replication	2.694238e-3
GO:0002092	positive regulation of receptor internalization	2.701383e-3
GO:0009890	negative regulation of biosynthetic process	2.709945e-3
GO:0048384	retinoic acid receptor signaling pathway	2.742687e-3
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	2.817892e-3
GO:0060540	diaphragm morphogenesis	2.817892e-3
GO:0060464	lung lobe formation	2.817892e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	2.839859e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	2.839859e-3
GO:0010633	negative regulation of epithelial cell migration	2.941335e-3
GO:0030261	chromosome condensation	3.011479e-3
GO:0080135	regulation of cellular response to stress	3.026488e-3
GO:0034372	very-low-density lipoprotein particle remodeling	3.066151e-3
GO:0022900	electron transport chain	3.079541e-3
GO:0001817	regulation of cytokine production	3.119179e-3
GO:0090084	negative regulation of inclusion body assembly	3.152509e-3
GO:0035054	embryonic heart tube anterior/posterior pattern specification	3.152509e-3
GO:0050901	leukocyte tethering or rolling	3.157835e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	3.284091e-3
GO:0021871	forebrain regionalization	3.314377e-3
GO:0060215	primitive hemopoiesis	3.324317e-3
GO:0071247	cellular response to chromate	3.328001e-3
GO:0018393	internal peptidyl-lysine acetylation	3.373645e-3
GO:0090399	replicative senescence	3.379232e-3
GO:0006658	phosphatidylserine metabolic process	3.379232e-3
GO:0021798	forebrain dorsal/ventral pattern formation	3.379232e-3
GO:0009790	embryo development	3.524274e-3
GO:0001705	ectoderm formation	3.612781e-3
GO:0032929	negative regulation of superoxide anion generation	3.612781e-3
GO:0016569	covalent chromatin modification	3.627196e-3
GO:0032495	response to muramyl dipeptide	3.676636e-3
GO:0060375	regulation of mast cell differentiation	3.739946e-3
GO:0045872	positive regulation of rhodopsin gene expression	3.789836e-3
GO:0071423	malate transmembrane transport	3.789836e-3
GO:0045090	retroviral genome replication	3.789836e-3
GO:0008300	isoprenoid catabolic process	3.789836e-3
GO:0002552	serotonin secretion by mast cell	3.789836e-3
GO:0015709	thiosulfate transport	3.789836e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	3.815392e-3
GO:0048333	mesodermal cell differentiation	3.827787e-3
GO:0000920	cytokinetic cell separation	3.864376e-3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	3.918793e-3
GO:0032091	negative regulation of protein binding	3.951967e-3
GO:0016571	histone methylation	3.991114e-3
GO:0018394	peptidyl-lysine acetylation	4.020889e-3
GO:0019240	citrulline biosynthetic process	4.024706e-3
GO:0006475	internal protein amino acid acetylation	4.067776e-3
GO:0071478	cellular response to radiation	4.093485e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	4.110583e-3
GO:0045837	negative regulation of membrane potential	4.159866e-3
GO:0060764	cell-cell signaling involved in mammary gland development	4.159866e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	4.159866e-3
GO:0002726	positive regulation of T cell cytokine production	4.202566e-3
GO:0060696	regulation of phospholipid catabolic process	4.262575e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	4.262575e-3
GO:0033129	positive regulation of histone phosphorylation	4.276110e-3
GO:0000415	negative regulation of histone H3-K36 methylation	4.276110e-3
GO:0002121	inter-male aggressive behavior	4.276110e-3
GO:0017156	calcium ion-dependent exocytosis	4.383398e-3
GO:0006338	chromatin remodeling	4.390362e-3
GO:0000305	response to oxygen radical	4.451322e-3
GO:0033700	phospholipid efflux	4.458122e-3
GO:0043414	macromolecule methylation	4.493969e-3
GO:0051351	positive regulation of ligase activity	4.633790e-3
GO:0031327	negative regulation of cellular biosynthetic process	4.703040e-3
GO:0043457	regulation of cellular respiration	4.703994e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	4.726633e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	4.759184e-3
GO:0021954	central nervous system neuron development	4.768370e-3
GO:0051310	metaphase plate congression	4.824161e-3
GO:0046677	response to antibiotic	4.856714e-3
GO:0042255	ribosome assembly	4.876593e-3
GO:0016570	histone modification	4.888629e-3
GO:0051953	negative regulation of amine transport	4.930615e-3
GO:0021535	cell migration in hindbrain	4.930615e-3
GO:0032928	regulation of superoxide anion generation	5.040592e-3
GO:0008535	respiratory chain complex IV assembly	5.040592e-3
GO:0045880	positive regulation of smoothened signaling pathway	5.099949e-3
GO:0017144	drug metabolic process	5.190403e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	5.311420e-3
GO:0050715	positive regulation of cytokine secretion	5.311722e-3
GO:0045862	positive regulation of proteolysis	5.413462e-3
GO:0032119	sequestering of zinc ion	5.430913e-3
GO:0090208	positive regulation of triglyceride metabolic process	5.490196e-3
GO:0007493	endodermal cell fate determination	5.533665e-3
GO:0051645	Golgi localization	5.574424e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	5.579262e-3
GO:0010565	regulation of cellular ketone metabolic process	5.579544e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.593556e-3
GO:0014040	positive regulation of Schwann cell differentiation	5.593556e-3
GO:0035435	phosphate ion transmembrane transport	5.593556e-3
GO:0034435	cholesterol esterification	5.624066e-3
GO:0060575	intestinal epithelial cell differentiation	5.624591e-3
GO:0032479	regulation of type I interferon production	5.642226e-3
GO:0031581	hemidesmosome assembly	5.680578e-3
GO:0045660	positive regulation of neutrophil differentiation	5.737245e-3
GO:0009826	unidimensional cell growth	5.737245e-3
GO:0002118	aggressive behavior	5.837647e-3
GO:0002553	histamine secretion by mast cell	5.856428e-3
GO:0034198	cellular response to amino acid starvation	5.856428e-3
GO:0070194	synaptonemal complex disassembly	5.927310e-3
GO:0071104	response to interleukin-9	5.927310e-3
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	5.927310e-3
GO:0021764	amygdala development	5.927310e-3
GO:0030149	sphingolipid catabolic process	6.030370e-3
GO:0008090	retrograde axon cargo transport	6.052173e-3
GO:0032494	response to peptidoglycan	6.061518e-3
GO:0042045	epithelial fluid transport	6.199795e-3
GO:0090304	nucleic acid metabolic process	6.299131e-3
GO:2000177	regulation of neural precursor cell proliferation	6.393327e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	6.464503e-3
GO:0042384	cilium assembly	6.485132e-3
GO:0071777	positive regulation of cell cycle cytokinesis	6.494216e-3
GO:0007339	binding of sperm to zona pellucida	6.707891e-3
GO:0048704	embryonic skeletal system morphogenesis	6.871117e-3
GO:0044267	cellular protein metabolic process	6.940841e-3
GO:0045629	negative regulation of T-helper 2 cell differentiation	6.944090e-3
GO:0034442	regulation of lipoprotein oxidation	6.944090e-3
GO:2000685	positive regulation of cellular response to X-ray	6.970123e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	6.970123e-3
GO:2001038	regulation of cellular response to drug	6.970123e-3
GO:0035988	chondrocyte proliferation	6.970123e-3
GO:0003131	mesodermal-endodermal cell signaling	6.970123e-3
GO:0035978	histone H2A-S139 phosphorylation	6.970123e-3
GO:0006467	protein thiol-disulfide exchange	6.970123e-3
GO:0031052	chromosome breakage	6.970123e-3
GO:0060271	cilium morphogenesis	7.161314e-3
GO:0006304	DNA modification	7.264963e-3
GO:0043388	positive regulation of DNA binding	7.285068e-3
GO:0031063	regulation of histone deacetylation	7.353405e-3
GO:0030855	epithelial cell differentiation	7.373661e-3
GO:0048680	positive regulation of axon regeneration	7.392813e-3
GO:0006659	phosphatidylserine biosynthetic process	7.392813e-3
GO:0060021	palate development	7.397102e-3
GO:0031929	TOR signaling cascade	7.533388e-3
GO:0019369	arachidonic acid metabolic process	7.533388e-3
GO:0021877	forebrain neuron fate commitment	7.657558e-3
GO:0034122	negative regulation of toll-like receptor signaling pathway	7.657558e-3
GO:0009896	positive regulation of catabolic process	7.685652e-3
GO:0071482	cellular response to light stimulus	7.724661e-3
GO:0001704	formation of primary germ layer	7.731753e-3
GO:0060433	bronchus development	7.801065e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	7.909049e-3
GO:0055107	Golgi to secretory granule transport	7.909049e-3
GO:0010189	vitamin E biosynthetic process	7.909049e-3
GO:0006021	inositol biosynthetic process	7.909049e-3
GO:0051569	regulation of histone H3-K4 methylation	8.047290e-3
GO:0046069	cGMP catabolic process	8.047290e-3
GO:0007141	male meiosis I	8.047290e-3
GO:0032855	positive regulation of Rac GTPase activity	8.086903e-3
GO:0045684	positive regulation of epidermis development	8.108940e-3
GO:0007140	male meiosis	8.169312e-3
GO:0048701	embryonic cranial skeleton morphogenesis	8.209059e-3
GO:2000178	negative regulation of neural precursor cell proliferation	8.340848e-3
GO:0065005	protein-lipid complex assembly	8.404020e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	8.417847e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	8.417847e-3
GO:0070316	regulation of G0 to G1 transition	8.417847e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	8.417847e-3
GO:0021905	forebrain-midbrain boundary formation	8.417847e-3
GO:0003322	pancreatic A cell development	8.417847e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	8.417847e-3
GO:0006091	generation of precursor metabolites and energy	8.526674e-3
GO:0060125	negative regulation of growth hormone secretion	8.541301e-3
GO:0006683	galactosylceramide catabolic process	8.541301e-3
GO:0051463	negative regulation of cortisol secretion	8.541301e-3
GO:0043967	histone H4 acetylation	8.549151e-3
GO:0032486	Rap protein signal transduction	8.573939e-3
GO:0045088	regulation of innate immune response	8.606481e-3
GO:2000683	regulation of cellular response to X-ray	8.661799e-3
GO:0051984	positive regulation of chromosome segregation	8.700556e-3
GO:0034498	early endosome to Golgi transport	8.700556e-3
GO:0008625	induction of apoptosis via death domain receptors	8.702636e-3
GO:0032268	regulation of cellular protein metabolic process	8.762199e-3
GO:0060558	regulation of calcidiol 1-monooxygenase activity	8.824222e-3
GO:0017004	cytochrome complex assembly	8.826098e-3
GO:2000779	regulation of double-strand break repair	8.865410e-3
GO:0035987	endodermal cell differentiation	8.930039e-3
GO:0051238	sequestering of metal ion	8.930971e-3
GO:0009303	rRNA transcription	9.128738e-3
GO:0051901	positive regulation of mitochondrial depolarization	9.228499e-3
GO:0003002	regionalization	9.300563e-3
GO:0001839	neural plate morphogenesis	9.388627e-3
GO:0090311	regulation of protein deacetylation	9.520453e-3
GO:0007090	regulation of S phase of mitotic cell cycle	9.530597e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	9.566860e-3
GO:0071415	cellular response to purine-containing compound	9.571444e-3
GO:0019452	L-cysteine catabolic process to taurine	9.571444e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	9.681787e-3
GO:0032722	positive regulation of chemokine production	9.704480e-3
GO:0019217	regulation of fatty acid metabolic process	9.708900e-3
GO:0003195	tricuspid valve formation	9.774768e-3
GO:0071103	DNA conformation change	9.846837e-3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	9.926224e-3
GO:0031915	positive regulation of synaptic plasticity	9.928190e-3
GO:0001945	lymph vessel development	1.003950e-2
GO:0000725	recombinational repair	1.003950e-2
GO:0030210	heparin biosynthetic process	1.007210e-2
GO:0060754	positive regulation of mast cell chemotaxis	1.009828e-2
GO:0006206	pyrimidine base metabolic process	1.019861e-2
GO:0003192	mitral valve formation	1.027462e-2
GO:0048147	negative regulation of fibroblast proliferation	1.035056e-2
GO:0006690	icosanoid metabolic process	1.048923e-2
GO:0019430	removal of superoxide radicals	1.068582e-2
GO:0071316	cellular response to nicotine	1.069081e-2
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.069081e-2
GO:0002439	chronic inflammatory response to antigenic stimulus	1.069081e-2
GO:0006596	polyamine biosynthetic process	1.069081e-2
GO:0048814	regulation of dendrite morphogenesis	1.070173e-2
GO:0071356	cellular response to tumor necrosis factor	1.075651e-2
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.078725e-2
GO:0033552	response to vitamin B3	1.078725e-2
GO:0030490	maturation of SSU-rRNA	1.082051e-2
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1.084461e-2
GO:0006323	DNA packaging	1.095380e-2
GO:0055119	relaxation of cardiac muscle	1.097030e-2
GO:0010424	DNA methylation on cytosine within a CG sequence	1.097030e-2
GO:0007109	cytokinesis, completion of separation	1.097030e-2
GO:0006729	tetrahydrobiopterin biosynthetic process	1.097030e-2
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	1.098352e-2
GO:0032107	regulation of response to nutrient levels	1.102459e-2
GO:0014912	negative regulation of smooth muscle cell migration	1.102459e-2
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1.103780e-2
GO:0021796	cerebral cortex regionalization	1.103780e-2
GO:0032648	regulation of interferon-beta production	1.107863e-2
GO:0010872	regulation of cholesterol esterification	1.110598e-2
GO:0015893	drug transport	1.110922e-2
GO:0042176	regulation of protein catabolic process	1.139503e-2
GO:0014014	negative regulation of gliogenesis	1.142829e-2
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.146666e-2
GO:0006817	phosphate ion transport	1.163602e-2
GO:0034968	histone lysine methylation	1.174438e-2
GO:0071224	cellular response to peptidoglycan	1.186815e-2