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MCL coexpression mm9:3521: Difference between revisions

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{{MCL_coexpression_mm9
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of Rab GTPase activity;0.012293869500904;57915!GO:0032482;Rab protein signal transduction;0.012293869500904;57915!GO:0032483;regulation of Rab protein signal transduction;0.012293869500904;57915!GO:0005097;Rab GTPase activator activity;0.012293869500904;57915!GO:0032318;regulation of Ras GTPase activity;0.012293869500904;57915!GO:0005099;Ras GTPase activator activity;0.0145912087510729;57915!GO:0043087;regulation of GTPase activity;0.0170304685726808;57915!GO:0046578;regulation of Ras protein signal transduction;0.0216360640400524;57915!GO:0051336;regulation of hydrolase activity;0.0216360640400524;57915!GO:0051056;regulation of small GTPase mediated signal transduction;0.0216360640400524;57915!GO:0007265;Ras protein signal transduction;0.0216360640400524;57915!GO:0005083;small GTPase regulator activity;0.0216360640400524;57915!GO:0005096;GTPase activator activity;0.0216360640400524;57915!GO:0008047;enzyme activator activity;0.0268762082162619;57915!GO:0050790;regulation of catalytic activity;0.0330385488182188;57915!GO:0030695;GTPase regulator activity;0.0330385488182188;57915!GO:0065009;regulation of a molecular function;0.0330385488182188;57915!GO:0009966;regulation of signal transduction;0.0330385488182188;57915!GO:0007264;small GTPase mediated signal 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|gostat_on_MCL_coexpression=GO:0032313;regulation of Rab GTPase activity;0.012293869500904;57915!GO:0032482;Rab protein signal transduction;0.012293869500904;57915!GO:0032483;regulation of Rab protein signal transduction;0.012293869500904;57915!GO:0005097;Rab GTPase activator activity;0.012293869500904;57915!GO:0032318;regulation of Ras GTPase activity;0.012293869500904;57915!GO:0005099;Ras GTPase activator activity;0.0145912087510729;57915!GO:0043087;regulation of GTPase activity;0.0170304685726808;57915!GO:0046578;regulation of Ras protein signal transduction;0.0216360640400524;57915!GO:0051336;regulation of hydrolase activity;0.0216360640400524;57915!GO:0051056;regulation of small GTPase mediated signal transduction;0.0216360640400524;57915!GO:0007265;Ras protein signal transduction;0.0216360640400524;57915!GO:0005083;small GTPase regulator activity;0.0216360640400524;57915!GO:0005096;GTPase activator activity;0.0216360640400524;57915!GO:0008047;enzyme activator activity;0.0268762082162619;57915!GO:0050790;regulation of catalytic activity;0.0330385488182188;57915!GO:0030695;GTPase regulator activity;0.0330385488182188;57915!GO:0065009;regulation of a molecular function;0.0330385488182188;57915!GO:0009966;regulation of signal transduction;0.0330385488182188;57915!GO:0007264;small GTPase mediated signal transduction;0.0330385488182188;57915!
|ontology_enrichment_celltype=CL:0000542!2.45e-07!13;CL:0000051!2.45e-07!13;CL:0002031!4.67e-07!25;CL:0002242!5.11e-07!16;CL:0000838!5.40e-07!12
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004119!9.35e-13!118;UBERON:0000925!9.35e-13!118;UBERON:0006595!9.35e-13!118;UBERON:0001007!1.23e-12!116;UBERON:0001555!1.23e-12!116;UBERON:0007026!1.23e-12!116;UBERON:0004921!4.22e-12!114;UBERON:0001004!1.48e-08!42;UBERON:0000065!4.60e-08!41;UBERON:0005409!3.15e-07!47
}}

Latest revision as of 20:14, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr5:64551446..64551459,+p6@LOC677502
p8@Tbc1d1
Mm9::chr5:64551466..64551509,+p1@LOC677502
p2@Tbc1d1
Mm9::chr5:64551510..64551535,+p3@LOC677502
p5@Tbc1d1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032313regulation of Rab GTPase activity0.012293869500904
GO:0032482Rab protein signal transduction0.012293869500904
GO:0032483regulation of Rab protein signal transduction0.012293869500904
GO:0005097Rab GTPase activator activity0.012293869500904
GO:0032318regulation of Ras GTPase activity0.012293869500904
GO:0005099Ras GTPase activator activity0.0145912087510729
GO:0043087regulation of GTPase activity0.0170304685726808
GO:0046578regulation of Ras protein signal transduction0.0216360640400524
GO:0051336regulation of hydrolase activity0.0216360640400524
GO:0051056regulation of small GTPase mediated signal transduction0.0216360640400524
GO:0007265Ras protein signal transduction0.0216360640400524
GO:0005083small GTPase regulator activity0.0216360640400524
GO:0005096GTPase activator activity0.0216360640400524
GO:0008047enzyme activator activity0.0268762082162619
GO:0050790regulation of catalytic activity0.0330385488182188
GO:0030695GTPase regulator activity0.0330385488182188
GO:0065009regulation of a molecular function0.0330385488182188
GO:0009966regulation of signal transduction0.0330385488182188
GO:0007264small GTPase mediated signal transduction0.0330385488182188



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure9.35e-13118
endoderm9.35e-13118
presumptive endoderm9.35e-13118
digestive system1.23e-12116
digestive tract1.23e-12116
primitive gut1.23e-12116
subdivision of digestive tract4.22e-12114
respiratory system1.48e-0842
respiratory tract4.60e-0841
gastrointestinal system3.15e-0747


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.35193
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.12.60474
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.14.47146
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.111.1471
MA0056.10
MA0057.14.34959
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.11.33581
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.12.46203
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.0430758
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.766354
MA0089.10
MA0090.10.762482
MA0091.11.91105
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.11.70277
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.13.81175
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.12.49617
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.11.16863
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.292366
MA0146.10.900029
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.40695
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.794478
MA0065.20.292912
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.925147
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.964824
MA0163.10.157796
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.26.11462
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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