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{{UBERON
{{UBERON
|id=UBERON:0003210
|alt_id=
|name=blood-cerebrospinal fluid barrier
|namespace=
|def="barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]." [MP:0006088]
|xref=
|is_a=UBERON:0000119
|synonym=
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]." [MP:0006088]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0003210
|is_a=UBERON:0000119
|is_obsolete=
|located_in=
|located_in=
|part_of=
|name=blood-cerebrospinal fluid barrier
|namespace=
|obo_creation_date=
|part_of=UBERON:0001016
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym=
|union_of=
|xref=
}}
}}

Revision as of 11:23, 12 September 2014

Name:blood-cerebrospinal fluid barrier
Definition:"barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]." [MP:0006088]

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000119(cell layer)
part_of:UBERON:0001016(nervous system)



Children

part of:CL:0000708 (leptomeningeal cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003210 (blood-cerebrospinal fluid barrier), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
8.98e-131FFCP PHASE2:Hg19::chr11:60680237..60680241,+#_db00189344c2181fec828b40ca175f76p@chr11:60680237..60680241, +
8.98e-131FFCP PHASE1:Hg19::chr11:60680237..60680241,+#_db00189344c2181fec828b40ca175f76p@chr11:60680237..60680241, +
3.48e-118FFCP PHASE1:Hg19::chr11:60680219..60680235,+#_a48a8a70470dc844e294129ab4b8ba2cp@chr11:60680219..60680235, +
3.48e-118FFCP PHASE2:Hg19::chr11:60680219..60680235,+#_a48a8a70470dc844e294129ab4b8ba2cp@chr11:60680219..60680235, +
5.69e-99FFCP PHASE1:Hg19::chr7:107720432..107720443,+#_43f12e47c16f31e2578d8489b5693eb3p@chr7:107720432..107720443, +
5.69e-99FFCP PHASE2:Hg19::chr7:107720432..107720443,+#_43f12e47c16f31e2578d8489b5693eb3p@chr7:107720432..107720443, +
6.24e-88FFCP PHASE1:Hg19::chr5:156811295..156811314,+#_f68a6e2bfecf749feb604dee408b0ce4p35@CYFIP2
6.24e-88FFCP PHASE2:Hg19::chr5:156811295..156811314,+#_f68a6e2bfecf749feb604dee408b0ce4p35@CYFIP2
7.51e-74FFCP PHASE1:Hg19::chr14:76072096..76072107,+#_391fe4c38344f986fb3d915738f9aee9p7@FLVCR2
7.51e-74FFCP PHASE2:Hg19::chr14:76072096..76072107,+#_391fe4c38344f986fb3d915738f9aee9p7@FLVCR2
2.39e-66FFCP PHASE2:Hg19::chr11:60680267..60680270,+#_86a714d72fa9f1963324155e73a5d691p@chr11:60680267..60680270, +
2.39e-66FFCP PHASE1:Hg19::chr11:60680267..60680270,+#_86a714d72fa9f1963324155e73a5d691p@chr11:60680267..60680270, +
1.68e-58FFCP PHASE1:Mm9::chr4:88940410..88940415,-#_d693be831ec5c5e5d86d28421056fe7bp6@Cdkn2a
1.68e-58FFCP PHASE2:Mm9::chr4:88940410..88940415,-#_d693be831ec5c5e5d86d28421056fe7bp6@Cdkn2a
4.17e-55FFCP PHASE2:Hg19::chr15:80843472..80843480,+#_05bdc138f5772a913b6159a859926397p22@ARNT2
4.17e-55FFCP PHASE1:Hg19::chr15:80843472..80843480,+#_05bdc138f5772a913b6159a859926397p22@ARNT2
1.59e-50FFCP PHASE1:Hg19::chr6:45618665..45618676,+#_3d3ea175621b2929c8381074b2b60f49p@chr6:45618665..45618676, +
1.59e-50FFCP PHASE2:Hg19::chr6:45618665..45618676,+#_3d3ea175621b2929c8381074b2b60f49p@chr6:45618665..45618676, +
4.73e-47FFCP PHASE2:Hg19::chr15:80842979..80842998,+#_a6de94c07ee2d163cf9dd72c36781f29p20@ARNT2
4.73e-47FFCP PHASE1:Hg19::chr15:80842979..80842998,+#_a6de94c07ee2d163cf9dd72c36781f29p20@ARNT2
7.81e-45FFCP PHASE2:Hg19::chr3:146517344..146517356,+#_598759358b3d4e8f9efbb4ebe332467cp@chr3:146517344..146517356, +
7.81e-45FFCP PHASE1:Hg19::chr3:146517344..146517356,+#_598759358b3d4e8f9efbb4ebe332467cp@chr3:146517344..146517356, +
2.97e-44FFCP PHASE1:Hg19::chr5:92498209..92498218,-#_ae99aabd979552baa72d70b123406fbfp@chr5:92498209..92498218, -
2.97e-44FFCP PHASE2:Hg19::chr5:92498209..92498218,-#_ae99aabd979552baa72d70b123406fbfp@chr5:92498209..92498218, -
7.52e-44FFCP PHASE1:Mm9::chr4:138749194..138749201,+#_11e6054917fc9bf561310539abf3877bp@chr4:138749194..138749201, +
7.52e-44FFCP PHASE2:Mm9::chr4:138749194..138749201,+#_11e6054917fc9bf561310539abf3877bp@chr4:138749194..138749201, +
1.24e-43FFCP PHASE2:Mm9::chr7:4729743..4729746,-#_583b472e4d9242f96ed0d43d9466c620p1@Il11
1.24e-43FFCP PHASE1:Mm9::chr7:4729743..4729746,-#_583b472e4d9242f96ed0d43d9466c620p1@Il11
1.14e-40FFCP PHASE1:Hg19::chr2:202562749..202562760,-#_f2d34d650e527759f374f5d39a17a6a4p7@MPP4
1.14e-40FFCP PHASE2:Hg19::chr2:202562749..202562760,-#_f2d34d650e527759f374f5d39a17a6a4p7@MPP4
6.35e-36FFCP PHASE2:Mm9::chr11:100820213..100820220,-#_80e0057e47c56afcfbe1a062c8f43f03p@chr11:100820213..100820220, -
6.35e-36FFCP PHASE1:Mm9::chr11:100820213..100820220,-#_80e0057e47c56afcfbe1a062c8f43f03p@chr11:100820213..100820220, -
7.74e-36FFCP PHASE2:Hg19::chr17:1013251..1013277,-#_f845bcf1060876219b9d09e923331447p@chr17:1013251..1013277, -
7.74e-36FFCP PHASE1:Hg19::chr17:1013251..1013277,-#_f845bcf1060876219b9d09e923331447p@chr17:1013251..1013277, -
1.24e-35FFCP PHASE1:Hg19::chr6:158490457..158490470,+#_767ae2a67270ee64f9ebf9e165f56b7dp10@SYNJ2
1.24e-35FFCP PHASE2:Hg19::chr6:158490457..158490470,+#_767ae2a67270ee64f9ebf9e165f56b7dp10@SYNJ2
2.13e-35FFCP PHASE1:Mm9::chr11:117093260..117093293,+#_11bfd4afe0956a352913b6945c0da4fbp34@Sept9
2.13e-35FFCP PHASE2:Mm9::chr11:117093260..117093293,+#_11bfd4afe0956a352913b6945c0da4fbp34@Sept9
2.25e-35FFCP PHASE1:Hg19::chr3:147088197..147088208,-#_9700a570d985c65e2a26654d9b09bcfcp@chr3:147088197..147088208, -
2.25e-35FFCP PHASE2:Hg19::chr3:147088197..147088208,-#_9700a570d985c65e2a26654d9b09bcfcp@chr3:147088197..147088208, -
2.45e-34FFCP PHASE1:Hg19::chr7:140341251..140341265,-#_2dfd9ee6c2bea27512f80548af5faa35p3@DENND2A
2.45e-34FFCP PHASE2:Hg19::chr7:140341251..140341265,-#_2dfd9ee6c2bea27512f80548af5faa35p3@DENND2A
1.09e-30FFCP PHASE1:Hg19::chr11:60680190..60680212,+#_9d46523bce4b1b50a089025646120526p@chr11:60680190..60680212, +
1.09e-30FFCP PHASE2:Hg19::chr11:60680190..60680212,+#_9d46523bce4b1b50a089025646120526p@chr11:60680190..60680212, +
4.77e-30FFCP PHASE2:Mm9::chr19:54120233..54120243,+#_746d474706a87b7d64132e1750e5f2b2p4@Adra2a
4.77e-30FFCP PHASE1:Mm9::chr2:119000878..119000908,-#_746d474706a87b7d64132e1750e5f2b2p@chr2:119000878..119000908, -
4.77e-30FFCP PHASE1:Mm9::chr19:54120233..54120243,+#_746d474706a87b7d64132e1750e5f2b2p4@Adra2a
4.77e-30FFCP PHASE2:Mm9::chr2:119000878..119000908,-#_746d474706a87b7d64132e1750e5f2b2p@chr2:119000878..119000908, -
5.61e-30FFCP PHASE1:Hg19::chr17:48346424..48346435,+#_308a02e0869de4543fd29cc31661d17cp@chr17:48346424..48346435, +
5.61e-30FFCP PHASE2:Hg19::chr17:48346424..48346435,+#_308a02e0869de4543fd29cc31661d17cp@chr17:48346424..48346435, +
7.41e-26FFCP PHASE1:Hg19::chrX:136649632..136649652,+#_71516ca01e6d6da04c9b1c17b4ee5c86p@chrX:136649632..136649652, +
7.41e-26FFCP PHASE2:Hg19::chrX:136649632..136649652,+#_71516ca01e6d6da04c9b1c17b4ee5c86p@chrX:136649632..136649652, +
1.35e-25FFCP PHASE1:Mm9::chr19:54120078..54120093,+#_6cb71868e40e5beee1f132f1779d909ep6@Adra2a
1.35e-25FFCP PHASE1:Mm9::chr5:28144366..28144367,-#_6cb71868e40e5beee1f132f1779d909ep@chr5:28144366..28144367, -
1.35e-25FFCP PHASE2:Mm9::chr19:54120078..54120093,+#_6cb71868e40e5beee1f132f1779d909ep6@Adra2a
1.35e-25FFCP PHASE2:Mm9::chr5:28144366..28144367,-#_6cb71868e40e5beee1f132f1779d909ep@chr5:28144366..28144367, -
2.99e-25FFCP PHASE1:Hg19::chr2:202562763..202562772,-#_afc43e55e4087c6aca3a7d4449064889p8@MPP4
2.99e-25FFCP PHASE2:Hg19::chr2:202562763..202562772,-#_afc43e55e4087c6aca3a7d4449064889p8@MPP4
4.87e-25FFCP PHASE2:Hg19::chr14:61654271..61654282,+#_a669060432aa1d309aaf10365831d6a6p30@PRKCH
4.87e-25FFCP PHASE1:Hg19::chr14:61654271..61654282,+#_a669060432aa1d309aaf10365831d6a6p30@PRKCH
8.75e-25FFCP PHASE1:Hg19::chr3:147130332..147130352,+#_43dbddfa79ee068392c13eae60d85dfbp@chr3:147130332..147130352, +
8.75e-25FFCP PHASE2:Hg19::chr3:147130332..147130352,+#_43dbddfa79ee068392c13eae60d85dfbp@chr3:147130332..147130352, +
1.03e-24FFCP PHASE2:Hg19::chr3:147114260..147114290,-#_abb3d0b610cf1463c5c51ce4188d1d36p3@ZIC4
1.03e-24FFCP PHASE1:Hg19::chr3:147114260..147114290,-#_abb3d0b610cf1463c5c51ce4188d1d36p3@ZIC4
9.24e-24FFCP PHASE2:Hg19::chr3:147131185..147131202,+#_e3b6c8f146cfcfb807f534f0978c0267p@chr3:147131185..147131202, +
9.24e-24FFCP PHASE1:Hg19::chr3:147131185..147131202,+#_e3b6c8f146cfcfb807f534f0978c0267p@chr3:147131185..147131202, +
2.62e-23FFCP PHASE1:Hg19::chr10:74020629..74020634,-#_8b1e6f56c26df128b976c2a0952b92eep@chr10:74020629..74020634, -
2.62e-23FFCP PHASE2:Hg19::chr10:74020629..74020634,-#_8b1e6f56c26df128b976c2a0952b92eep@chr10:74020629..74020634, -
3.06e-23FFCP PHASE1:Mm9::chr5:136364908..136364912,+#_ab1c6ef7b5dc546994c7b54a34ffdcc2p@chr5:136364908..136364912, +
3.06e-23FFCP PHASE2:Mm9::chr5:136364908..136364912,+#_ab1c6ef7b5dc546994c7b54a34ffdcc2p@chr5:136364908..136364912, +
3.27e-23FFCP PHASE2:Hg19::chr2:202562827..202562835,-#_13d5a16f7aa8baf365c2709cc0606183p10@MPP4
3.27e-23FFCP PHASE1:Hg19::chr3:147128275..147128285,+#_13d5a16f7aa8baf365c2709cc0606183p5@AB464362
3.27e-23FFCP PHASE1:Hg19::chr2:202562827..202562835,-#_13d5a16f7aa8baf365c2709cc0606183p10@MPP4
3.27e-23FFCP PHASE2:Hg19::chr3:147128275..147128285,+#_13d5a16f7aa8baf365c2709cc0606183p5@AB464362
4.61e-23FFCP PHASE1:Hg19::chr10:69902750..69902779,+#_677768a66ab5b5fc7a115e6a3528df6bp@chr10:69902750..69902779, +
4.61e-23FFCP PHASE2:Hg19::chr10:69902750..69902779,+#_677768a66ab5b5fc7a115e6a3528df6bp@chr10:69902750..69902779, +
5.15e-23FFCP PHASE2:Hg19::chr12:108732917..108732935,-#_0eef0217412f0d46e6d28b59a89846c1p5@CMKLR1
5.15e-23FFCP PHASE1:Hg19::chr12:108732917..108732935,-#_0eef0217412f0d46e6d28b59a89846c1p5@CMKLR1
6.44e-23FFCP PHASE2:Hg19::chr3:147123837..147123848,-#_1fa39c4207e8a61e3c3fe9363b2ee02fp7@ZIC4
6.44e-23FFCP PHASE1:Hg19::chr3:147123837..147123848,-#_1fa39c4207e8a61e3c3fe9363b2ee02fp7@ZIC4
9.5e-23FFCP PHASE2:Mm9::chr17:45832371..45832382,+#_de48f36a144b621e0e10a662a3ab6823p4@Mrpl14
9.5e-23FFCP PHASE1:Mm9::chr17:45832371..45832382,+#_de48f36a144b621e0e10a662a3ab6823p4@Mrpl14
9.47e-22FFCP PHASE1:Hg19::chr20:2781623..2781635,-#_173de7d0b9ef27721df34c02d4fae2b5p5@CPXM1
9.47e-22FFCP PHASE2:Hg19::chr20:2781623..2781635,-#_173de7d0b9ef27721df34c02d4fae2b5p5@CPXM1
3.63e-21FFCP PHASE2:Hg19::chr10:112207187..112207199,-#_42bd497fba0325ee0ec40cae978b4067p@chr10:112207187..112207199, -
3.63e-21FFCP PHASE1:Hg19::chr10:112207187..112207199,-#_42bd497fba0325ee0ec40cae978b4067p@chr10:112207187..112207199, -
6.43e-21FFCP PHASE2:Mm9::chr19:10067446..10067483,-#_001601903651002b8c899173a6dd935bp5@Best1, p5@LOC100504840
6.43e-21FFCP PHASE1:Mm9::chr19:10067446..10067483,-#_001601903651002b8c899173a6dd935bp5@Best1, p5@LOC100504840
8.07e-21FFCP PHASE1:Mm9::chr2:35140218..35140229,+#_171cdbb80d0d6313996e20ddb7006405p@chr2:35140218..35140229, +
8.07e-21FFCP PHASE2:Mm9::chr2:35140218..35140229,+#_171cdbb80d0d6313996e20ddb7006405p@chr2:35140218..35140229, +
8.47e-21FFCP PHASE1:Hg19::chr6:151562148..151562162,+#_eda0c31a51dcaff80ed35a64fab038fbp@chr6:151562148..151562162, +
8.47e-21FFCP PHASE2:Hg19::chr6:151562148..151562162,+#_eda0c31a51dcaff80ed35a64fab038fbp@chr6:151562148..151562162, +
1.74e-20FFCP PHASE1:Hg19::chr3:147127489..147127503,+#_29e14d40faf860c3ebcfa717be39ad01p11@ZIC1
1.74e-20FFCP PHASE2:Hg19::chr3:147127489..147127503,+#_29e14d40faf860c3ebcfa717be39ad01p11@ZIC1
2.05e-20FFCP PHASE2:Hg19::chr9:6565462..6565475,-#_e180ec5c3db3e84ecc06a8829a371f1bp5@GLDC
2.05e-20FFCP PHASE1:Hg19::chr9:6565462..6565475,-#_e180ec5c3db3e84ecc06a8829a371f1bp5@GLDC
3.01e-20FFCP PHASE1:Hg19::chr3:147131775..147131783,+#_d97153df199850891dc77dded391ebfap@chr3:147131775..147131783, +
3.01e-20FFCP PHASE2:Hg19::chr3:147131775..147131783,+#_d97153df199850891dc77dded391ebfap@chr3:147131775..147131783, +
3.91e-20FFCP PHASE2:Mm9::chr11:86449013..86449037,-#_a53f0ffe851a9d0fb1005fe2b0449d01p@chr11:86449013..86449037, -
3.91e-20FFCP PHASE1:Mm9::chr11:86449013..86449037,-#_a53f0ffe851a9d0fb1005fe2b0449d01p@chr11:86449013..86449037, -

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