CL:0000040: Difference between revisions
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{{CL | {{CL | ||
| | |alt_id= | ||
|comment=Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. | |comment=Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. | ||
|created_by= | |created_by= | ||
| | |def="A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740] | ||
|derives_from= | |derives_from= | ||
|develops_from=CL:0002009 | |develops_from=CL:0002009 | ||
|disjoint_from= | |||
|has_quality= | |has_quality= | ||
|id=CL:0000040 | |||
|is_a=CL:0000763 ;;CL:0002194 | |||
|is_obsolete= | |||
|located_in= | |located_in= | ||
|name=monoblast | |||
|namespace=FANTOM | |||
|obo_creation_date= | |||
|part_of= | |part_of= | ||
|preceded_by= | |||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | ||
| | |subset= | ||
| | |synonym="CFU-M" RELATED [];;"colony forming unit macrophage" RELATED [];;"monocyte stem cell" RELATED [] | ||
|union_of= | |||
|xref=FMA:83553 | |||
}} | }} |
Latest revision as of 16:28, 12 September 2014
Name: | monoblast | |
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Namespace: | FANTOM | |
Definition: | "A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740] | |
Xrefs: |
| |
Synonyms: |
"CFU-M" RELATED [] "colony forming unit macrophage" RELATED [] "monocyte stem cell" RELATED [] | |
Comments: | Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000763(myeloid cell),CL:0002194(monopoietic cell) |
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develops_from: | CL:0002009(macrophage dendritic cell progenitor) |
Children
develops from: | CL:0000559 (promonocyte) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000040 (monoblast), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data