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Line 13: Line 13:
|located_in=
|located_in=
|name=hepatocyte
|name=hepatocyte
|namespace=cell;;efo
|namespace=FANTOM
|obo_creation_date=
|obo_creation_date=
|part_of=UBERON:0002107
|part_of=UBERON:0002107

Latest revision as of 16:31, 12 September 2014

Name:hepatocyte
Namespace:FANTOM
Definition:"The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, ISBN:0412046911, MESH:A.11.436.348, PMID:19717280]
Xrefs:
links:

BTO:0000575

FMA:14515


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000066(epithelial cell),CL:0000181(metabolising cell),CL:0000417(endopolyploid cell),CL:0002371(somatic cell)
develops_from:CL:0005026(hepatoblast)
part_of:UBERON:0002107(liver)



Children


is a:FF:0000018 (canine hepatocyte),FF:0000034 (chicken hepatocyte),FF:0000150 (rat hepatocyte),CL:0002538 (intrahepatic bile duct epithelial cell),CL:1000398 (endothelial cell of hepatic sinusoid),FF:13580-146C7 (hepatocytes, sham operation, biol_rep1),FF:13581-146C8 (hepatocytes, sham operation, biol_rep2),FF:13582-146C9 (hepatocytes, sham operation, biol_rep3),FF:13583-146D1 (hepatocytes, partial hepatectomy, 02hr, biol_rep1),FF:13584-146D2 (hepatocytes, partial hepatectomy, 02hr, biol_rep2),FF:13585-146D3 (hepatocytes, partial hepatectomy, 02hr, biol_rep3),FF:13586-146D4 (hepatocytes, partial hepatectomy, 30hr, biol_rep1)
derives from:FF:0000078 (human hepatocyte sample),FF:0000109 (mouse hepatocyte sample),FF:0100578 (hepatoma cell line sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000182 (hepatocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data