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{{CL
{{CL
|id=CL:0000898
|alt_id=
|name=naive T cell
|namespace=efo
|def="Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
|xref=
|is_a=CL:0002419
|synonym="naive T lymphocyte" EXACT [];;"naive T-cell" EXACT [];;"naive T-lymphocyte" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
|subset=
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000898
|is_a=CL:0002419
|is_obsolete=
|located_in=
|located_in=
|name=naive T cell
|namespace=FANTOM
|obo_creation_date=
|part_of=
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl
|is_obsolete=
|preceded_by=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|subset=
|synonym="naive T lymphocyte" EXACT [];;"naive T-cell" EXACT [];;"naive T-lymphocyte" EXACT []
|union_of=
|xref=
}}
}}

Latest revision as of 16:38, 12 September 2014

Name:naive T cell
Namespace:FANTOM
Definition:"Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
Synonyms: "naive T lymphocyte" EXACT []
"naive T-cell" EXACT []
"naive T-lymphocyte" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0002419(mature T cell)



Children


is a:CL:0000895 (naive thymus-derived CD4-positive, alpha-beta T cell),CL:0002677 (naive regulatory T cell)
disjoint from:CL:0000813 (memory T cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))

Mouse (Mus musculus)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000898 (naive T cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data