Novel motif:79

name:	motif79_ACATCTACAA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	1.068932e-17
GO:0014866	skeletal myofibril assembly	4.843161e-17
GO:0048747	muscle fiber development	1.714987e-16
GO:0048856	anatomical structure development	2.665631e-16
GO:0010038	response to metal ion	2.960143e-16
GO:0055002	striated muscle cell development	4.830660e-16
GO:0030261	chromosome condensation	6.538789e-16
GO:0055001	muscle cell development	7.884028e-16
GO:0032502	developmental process	1.297763e-15
GO:0030241	skeletal muscle myosin thick filament assembly	2.467896e-15
GO:0031032	actomyosin structure organization	2.548240e-15
GO:0051592	response to calcium ion	3.631857e-15
GO:0010035	response to inorganic substance	5.083206e-15
GO:0032501	multicellular organismal process	1.708367e-14
GO:0030239	myofibril assembly	2.041734e-14
GO:0051641	cellular localization	2.964637e-14
GO:0072358	cardiovascular system development	6.936258e-14
GO:0002576	platelet degranulation	7.200670e-14
GO:0051234	establishment of localization	7.738135e-14
GO:0034621	cellular macromolecular complex subunit organization	1.057453e-13
GO:0048739	cardiac muscle fiber development	1.379095e-13
GO:0048646	anatomical structure formation involved in morphogenesis	1.666846e-13
GO:0009888	tissue development	1.723754e-13
GO:0009653	anatomical structure morphogenesis	1.819948e-13
GO:0002694	regulation of leukocyte activation	2.329990e-13
GO:0018149	peptide cross-linking	3.116179e-13
GO:0006323	DNA packaging	4.764179e-13
GO:0006928	cellular component movement	8.801718e-13
GO:0051649	establishment of localization in cell	1.015141e-12
GO:0007275	multicellular organismal development	1.023434e-12
GO:0030240	skeletal muscle thin filament assembly	1.491601e-12
GO:0051179	localization	1.601125e-12
GO:0006996	organelle organization	1.827331e-12
GO:0050865	regulation of cell activation	2.969141e-12
GO:0006810	transport	3.170049e-12
GO:0042060	wound healing	3.576186e-12
GO:0030168	platelet activation	3.930830e-12
GO:0034622	cellular macromolecular complex assembly	4.100082e-12
GO:0032764	negative regulation of mast cell cytokine production	5.312722e-12
GO:0042692	muscle cell differentiation	8.535503e-12
GO:0048731	system development	1.025693e-11
GO:0030299	intestinal cholesterol absorption	1.132302e-11
GO:0001775	cell activation	1.231241e-11
GO:0043623	cellular protein complex assembly	1.400866e-11
GO:0022600	digestive system process	1.605261e-11
GO:0048513	organ development	1.698658e-11
GO:0071103	DNA conformation change	2.045950e-11
GO:0007076	mitotic chromosome condensation	2.312205e-11
GO:0050794	regulation of cellular process	3.341002e-11
GO:0071844	cellular component assembly at cellular level	3.863521e-11
GO:0030029	actin filament-based process	4.144456e-11
GO:0032940	secretion by cell	4.213840e-11
GO:0051146	striated muscle cell differentiation	4.356343e-11
GO:0001101	response to acid	4.680650e-11
GO:0065008	regulation of biological quality	4.872402e-11
GO:0002376	immune system process	5.045312e-11
GO:0061061	muscle structure development	5.325728e-11
GO:0071842	cellular component organization at cellular level	7.000223e-11
GO:0030048	actin filament-based movement	7.612150e-11
GO:0046903	secretion	7.750301e-11
GO:0050892	intestinal absorption	9.453952e-11
GO:0070252	actin-mediated cell contraction	9.589901e-11
GO:0010927	cellular component assembly involved in morphogenesis	1.012868e-10
GO:0009611	response to wounding	1.031175e-10
GO:0003008	system process	1.093592e-10
GO:0002682	regulation of immune system process	1.300713e-10
GO:0007586	digestion	1.379713e-10
GO:0065007	biological regulation	1.573227e-10
GO:0006788	heme oxidation	2.341776e-10
GO:0071363	cellular response to growth factor stimulus	2.643287e-10
GO:0006940	regulation of smooth muscle contraction	2.972227e-10
GO:0045214	sarcomere organization	3.259448e-10
GO:0030049	muscle filament sliding	4.009494e-10
GO:0050789	regulation of biological process	4.051155e-10
GO:0071841	cellular component organization or biogenesis at cellular level	4.256155e-10
GO:0048769	sarcomerogenesis	6.076204e-10
GO:0010838	positive regulation of keratinocyte proliferation	6.319870e-10
GO:0061033	secretion by lung epithelial cell involved in lung growth	6.319870e-10
GO:0030036	actin cytoskeleton organization	6.435128e-10
GO:0071230	cellular response to amino acid stimulus	8.976172e-10
GO:0055003	cardiac myofibril assembly	9.226216e-10
GO:0014806	smooth muscle hyperplasia	1.133818e-9
GO:0050867	positive regulation of cell activation	1.354800e-9
GO:0071229	cellular response to acid	1.434663e-9
GO:0031295	T cell costimulation	1.860101e-9
GO:0002696	positive regulation of leukocyte activation	1.969521e-9
GO:0051249	regulation of lymphocyte activation	1.974129e-9
GO:0003012	muscle system process	2.315403e-9
GO:0043500	muscle adaptation	2.419035e-9
GO:0048584	positive regulation of response to stimulus	2.471892e-9
GO:0045766	positive regulation of angiogenesis	3.554228e-9
GO:0055013	cardiac muscle cell development	3.875920e-9
GO:0050776	regulation of immune response	4.691333e-9
GO:0050878	regulation of body fluid levels	7.374140e-9
GO:0071417	cellular response to organic nitrogen	8.133042e-9
GO:0071840	cellular component organization or biogenesis	9.033354e-9
GO:0007507	heart development	1.039529e-8
GO:0071418	cellular response to amine stimulus	1.069475e-8
GO:0000819	sister chromatid segregation	1.156787e-8
GO:0006950	response to stress	1.221952e-8
GO:0043200	response to amino acid stimulus	1.276830e-8
GO:0000070	mitotic sister chromatid segregation	1.287594e-8
GO:0032763	regulation of mast cell cytokine production	1.394711e-8
GO:0009605	response to external stimulus	1.897057e-8
GO:0007015	actin filament organization	1.914210e-8
GO:0051251	positive regulation of lymphocyte activation	3.331324e-8
GO:0032989	cellular component morphogenesis	3.415360e-8
GO:0048661	positive regulation of smooth muscle cell proliferation	4.114783e-8
GO:0010667	negative regulation of cardiac muscle cell apoptosis	4.294336e-8
GO:0048518	positive regulation of biological process	4.813429e-8
GO:0035051	cardiac cell differentiation	4.816724e-8
GO:0001568	blood vessel development	5.158805e-8
GO:0016043	cellular component organization	5.178376e-8
GO:0061088	regulation of sequestering of zinc ion	5.586398e-8
GO:0044241	lipid digestion	6.794853e-8
GO:0032103	positive regulation of response to external stimulus	6.876578e-8
GO:0050851	antigen receptor-mediated signaling pathway	7.023978e-8
GO:0007010	cytoskeleton organization	7.574910e-8
GO:0048583	regulation of response to stimulus	7.820219e-8
GO:0032964	collagen biosynthetic process	9.327432e-8
GO:0051272	positive regulation of cellular component movement	9.762714e-8
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	9.797032e-8
GO:0002429	immune response-activating cell surface receptor signaling pathway	9.856337e-8
GO:0001944	vasculature development	1.034119e-7
GO:0002684	positive regulation of immune system process	1.086213e-7
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.242673e-7
GO:0005983	starch catabolic process	1.258631e-7
GO:0048468	cell development	1.265874e-7
GO:0007596	blood coagulation	1.326883e-7
GO:0007165	signal transduction	1.439244e-7
GO:0048738	cardiac muscle tissue development	1.442831e-7
GO:0030199	collagen fibril organization	1.471402e-7
GO:0043305	negative regulation of mast cell degranulation	1.487281e-7
GO:0007599	hemostasis	1.535832e-7
GO:0060537	muscle tissue development	1.622523e-7
GO:0051716	cellular response to stimulus	1.666811e-7
GO:0030335	positive regulation of cell migration	1.762764e-7
GO:0050864	regulation of B cell activation	1.791794e-7
GO:0031296	B cell costimulation	1.806782e-7
GO:0046660	female sex differentiation	1.815836e-7
GO:0040017	positive regulation of locomotion	1.902592e-7
GO:0030890	positive regulation of B cell proliferation	1.931230e-7
GO:0002548	monocyte chemotaxis	1.954016e-7
GO:0043503	skeletal muscle fiber adaptation	2.222006e-7
GO:0044036	cell wall macromolecule metabolic process	2.308870e-7
GO:0014706	striated muscle tissue development	2.324086e-7
GO:0045663	positive regulation of myoblast differentiation	2.360925e-7
GO:0030154	cell differentiation	2.511954e-7
GO:0040011	locomotion	2.526915e-7
GO:0048520	positive regulation of behavior	2.771654e-7
GO:2000147	positive regulation of cell motility	2.960542e-7
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	2.976656e-7
GO:0042167	heme catabolic process	3.100066e-7
GO:0048869	cellular developmental process	3.940219e-7
GO:0045765	regulation of angiogenesis	4.034345e-7
GO:0070848	response to growth factor stimulus	4.106111e-7
GO:0043550	regulation of lipid kinase activity	4.335143e-7
GO:0002920	regulation of humoral immune response	4.366693e-7
GO:0055007	cardiac muscle cell differentiation	4.980259e-7
GO:0046545	development of primary female sexual characteristics	5.545450e-7
GO:0022607	cellular component assembly	5.584790e-7
GO:0071157	negative regulation of cell cycle arrest	5.725089e-7
GO:0033007	negative regulation of mast cell activation involved in immune response	6.016493e-7
GO:0060437	lung growth	6.095850e-7
GO:0010664	negative regulation of striated muscle cell apoptosis	6.783067e-7
GO:0006887	exocytosis	6.837846e-7
GO:0034394	protein localization at cell surface	7.011681e-7
GO:0046824	positive regulation of nucleocytoplasmic transport	7.013030e-7
GO:0032388	positive regulation of intracellular transport	7.044394e-7
GO:0006458	'de novo' protein folding	7.160248e-7
GO:0016998	cell wall macromolecule catabolic process	7.335292e-7
GO:0006955	immune response	7.843287e-7
GO:0009306	protein secretion	9.007865e-7
GO:0044085	cellular component biogenesis	1.058549e-6
GO:0048870	cell motility	1.078366e-6
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.084432e-6
GO:0006936	muscle contraction	1.176514e-6
GO:0032963	collagen metabolic process	1.199444e-6
GO:0014075	response to amine stimulus	1.217289e-6
GO:0090316	positive regulation of intracellular protein transport	1.342930e-6
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.441658e-6
GO:0030888	regulation of B cell proliferation	1.455236e-6
GO:0044259	multicellular organismal macromolecule metabolic process	1.468837e-6
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	1.513149e-6
GO:0044236	multicellular organismal metabolic process	1.541578e-6
GO:0009991	response to extracellular stimulus	1.548047e-6
GO:0061153	trachea gland development	1.603046e-6
GO:0071577	zinc ion transmembrane transport	1.775511e-6
GO:0051084	'de novo' posttranslational protein folding	1.864257e-6
GO:0071294	cellular response to zinc ion	1.886058e-6
GO:0042221	response to chemical stimulus	1.909410e-6
GO:0002757	immune response-activating signal transduction	1.919437e-6
GO:0002885	positive regulation of hypersensitivity	1.963658e-6
GO:0050863	regulation of T cell activation	2.052668e-6
GO:0002764	immune response-regulating signaling pathway	2.232696e-6
GO:0001525	angiogenesis	2.374316e-6
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2.457060e-6
GO:0006644	phospholipid metabolic process	2.532981e-6
GO:0006434	seryl-tRNA aminoacylation	2.587653e-6
GO:0035924	cellular response to vascular endothelial growth factor stimulus	2.753799e-6
GO:0048263	determination of dorsal identity	2.768552e-6
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	2.768552e-6
GO:0006333	chromatin assembly or disassembly	2.788754e-6
GO:0048522	positive regulation of cellular process	2.917491e-6
GO:0060541	respiratory system development	3.148853e-6
GO:0006629	lipid metabolic process	3.156535e-6
GO:0007517	muscle organ development	3.208223e-6
GO:0007162	negative regulation of cell adhesion	3.283008e-6
GO:0031667	response to nutrient levels	3.510186e-6
GO:0014805	smooth muscle adaptation	3.514262e-6
GO:0001935	endothelial cell proliferation	3.534448e-6
GO:0002683	negative regulation of immune system process	3.599967e-6
GO:0055069	zinc ion homeostasis	3.769442e-6
GO:0006069	ethanol oxidation	3.839551e-6
GO:0002719	negative regulation of cytokine production involved in immune response	3.992276e-6
GO:0043392	negative regulation of DNA binding	4.195405e-6
GO:0051222	positive regulation of protein transport	4.221944e-6
GO:0006941	striated muscle contraction	4.286033e-6
GO:0065009	regulation of molecular function	4.373271e-6
GO:0051098	regulation of binding	4.699174e-6
GO:0050871	positive regulation of B cell activation	4.737261e-6
GO:0002820	negative regulation of adaptive immune response	5.031056e-6
GO:0010665	regulation of cardiac muscle cell apoptosis	5.040103e-6
GO:0051149	positive regulation of muscle cell differentiation	5.107708e-6
GO:0008610	lipid biosynthetic process	5.109664e-6
GO:0090218	positive regulation of lipid kinase activity	5.172103e-6
GO:0021881	Wnt receptor signaling pathway involved in forebrain neuron fate commitment	5.174451e-6
GO:0016192	vesicle-mediated transport	5.496976e-6
GO:0043549	regulation of kinase activity	6.039143e-6
GO:0031099	regeneration	6.092418e-6
GO:0048514	blood vessel morphogenesis	6.165900e-6
GO:0050777	negative regulation of immune response	6.499560e-6
GO:0007154	cell communication	6.547454e-6
GO:0048262	determination of dorsal/ventral asymmetry	6.636656e-6
GO:0033036	macromolecule localization	6.826568e-6
GO:0023052	signaling	7.217555e-6
GO:0045023	G0 to G1 transition	7.834508e-6
GO:0008284	positive regulation of cell proliferation	7.889669e-6
GO:0007166	cell surface receptor linked signaling pathway	8.167054e-6
GO:0000902	cell morphogenesis	8.288300e-6
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	8.914444e-6
GO:0060548	negative regulation of cell death	8.973273e-6
GO:0016477	cell migration	9.554751e-6
GO:0048872	homeostasis of number of cells	1.010873e-5
GO:0010243	response to organic nitrogen	1.017754e-5
GO:0010559	regulation of glycoprotein biosynthetic process	1.030278e-5
GO:0043933	macromolecular complex subunit organization	1.060900e-5
GO:0048762	mesenchymal cell differentiation	1.073566e-5
GO:0048878	chemical homeostasis	1.129185e-5
GO:0010656	negative regulation of muscle cell apoptosis	1.184287e-5
GO:0002883	regulation of hypersensitivity	1.258114e-5
GO:0065003	macromolecular complex assembly	1.377095e-5
GO:0051346	negative regulation of hydrolase activity	1.478004e-5
GO:0048016	inositol phosphate-mediated signaling	1.498786e-5
GO:0033004	negative regulation of mast cell activation	1.517739e-5
GO:0051276	chromosome organization	1.576646e-5
GO:0019637	organophosphate metabolic process	1.602568e-5
GO:0002634	regulation of germinal center formation	1.637829e-5
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	1.664864e-5
GO:0051258	protein polymerization	1.672546e-5
GO:0034764	positive regulation of transmembrane transport	1.710699e-5
GO:0044255	cellular lipid metabolic process	1.767532e-5
GO:0008283	cell proliferation	1.786645e-5
GO:0007292	female gamete generation	1.906836e-5
GO:0035295	tube development	1.928081e-5
GO:0051094	positive regulation of developmental process	1.932478e-5
GO:0006959	humoral immune response	1.949103e-5
GO:0006349	regulation of gene expression by genetic imprinting	2.026031e-5
GO:0050793	regulation of developmental process	2.032513e-5
GO:0042307	positive regulation of protein import into nucleus	2.074796e-5
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	2.082768e-5
GO:0022603	regulation of anatomical structure morphogenesis	2.119463e-5
GO:0051024	positive regulation of immunoglobulin secretion	2.124223e-5
GO:0002697	regulation of immune effector process	2.156395e-5
GO:0051338	regulation of transferase activity	2.163945e-5
GO:0060693	regulation of branching involved in salivary gland morphogenesis	2.167611e-5
GO:0050900	leukocyte migration	2.201357e-5
GO:0050870	positive regulation of T cell activation	2.319057e-5
GO:2000679	positive regulation of transcription regulatory region DNA binding	2.424505e-5
GO:0007213	muscarinic acetylcholine receptor signaling pathway	2.448625e-5
GO:0009615	response to virus	2.697043e-5
GO:0006650	glycerophospholipid metabolic process	2.705128e-5
GO:0007059	chromosome segregation	2.746557e-5
GO:0048285	organelle fission	2.843046e-5
GO:0030540	female genitalia development	2.889417e-5
GO:0010662	regulation of striated muscle cell apoptosis	2.988601e-5
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	3.070671e-5
GO:0001817	regulation of cytokine production	3.136742e-5
GO:0019538	protein metabolic process	3.256450e-5
GO:0046854	phosphatidylinositol phosphorylation	3.279110e-5
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.308060e-5
GO:0061039	ovum-producing ovary development	3.353877e-5
GO:0007067	mitosis	3.368108e-5
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	3.406332e-5
GO:0014033	neural crest cell differentiation	3.536846e-5
GO:0097022	lymphocyte migration into lymph node	3.663448e-5
GO:0030301	cholesterol transport	3.771667e-5
GO:0001776	leukocyte homeostasis	3.774383e-5
GO:0014031	mesenchymal cell development	3.916514e-5
GO:0050790	regulation of catalytic activity	3.962241e-5
GO:0008104	protein localization	4.001117e-5
GO:0071514	genetic imprinting	4.144802e-5
GO:0043069	negative regulation of programmed cell death	4.171652e-5
GO:0002577	regulation of antigen processing and presentation	4.398641e-5
GO:0032848	negative regulation of cellular pH reduction	4.414564e-5
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	4.414564e-5
GO:0021747	cochlear nucleus development	4.414564e-5
GO:0014042	positive regulation of neuron maturation	4.414564e-5
GO:0034613	cellular protein localization	4.473911e-5
GO:0034720	histone H3-K4 demethylation	4.489520e-5
GO:0072610	interleukin-12 secretion	4.603528e-5
GO:0000114	regulation of transcription involved in G1 phase of mitotic cell cycle	4.603528e-5
GO:0002408	myeloid dendritic cell chemotaxis	4.603528e-5
GO:0000087	M phase of mitotic cell cycle	4.708019e-5
GO:0043129	surfactant homeostasis	4.793324e-5
GO:0002260	lymphocyte homeostasis	4.852117e-5
GO:0033561	regulation of water loss via skin	4.861356e-5
GO:2000107	negative regulation of leukocyte apoptosis	4.920543e-5
GO:0006937	regulation of muscle contraction	4.972543e-5
GO:0060897	neural plate regionalization	5.009603e-5
GO:0008206	bile acid metabolic process	5.129488e-5
GO:0034154	toll-like receptor 7 signaling pathway	5.214218e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	5.242345e-5
GO:0070727	cellular macromolecule localization	5.276947e-5
GO:0009887	organ morphogenesis	5.312807e-5
GO:0008654	phospholipid biosynthetic process	5.340334e-5
GO:0051239	regulation of multicellular organismal process	5.442332e-5
GO:0042592	homeostatic process	5.500841e-5
GO:0030449	regulation of complement activation	5.516641e-5
GO:0050921	positive regulation of chemotaxis	5.526737e-5
GO:0070271	protein complex biogenesis	5.527125e-5
GO:0043066	negative regulation of apoptosis	5.583250e-5
GO:0010837	regulation of keratinocyte proliferation	5.584913e-5
GO:0002253	activation of immune response	5.704898e-5
GO:0050853	B cell receptor signaling pathway	5.772900e-5
GO:0045738	negative regulation of DNA repair	5.810586e-5
GO:0055080	cation homeostasis	5.859533e-5
GO:0022602	ovulation cycle process	5.909441e-5
GO:0010810	regulation of cell-substrate adhesion	6.000558e-5
GO:0003007	heart morphogenesis	6.011796e-5
GO:0002703	regulation of leukocyte mediated immunity	6.188550e-5
GO:0030155	regulation of cell adhesion	6.240877e-5
GO:0048729	tissue morphogenesis	6.295556e-5
GO:2000008	regulation of protein localization at cell surface	6.543122e-5
GO:0060638	mesenchymal-epithelial cell signaling	6.569709e-5
GO:0051187	cofactor catabolic process	6.596439e-5
GO:0031497	chromatin assembly	6.715208e-5
GO:0002040	sprouting angiogenesis	6.787246e-5
GO:0006952	defense response	7.121238e-5
GO:0003219	cardiac right ventricle formation	7.483791e-5
GO:0050801	ion homeostasis	7.523955e-5
GO:0050707	regulation of cytokine secretion	7.558646e-5
GO:0006829	zinc ion transport	7.581758e-5
GO:0043501	skeletal muscle adaptation	7.594219e-5
GO:0051640	organelle localization	7.594332e-5
GO:0015918	sterol transport	7.606741e-5
GO:0010466	negative regulation of peptidase activity	7.623946e-5
GO:0006461	protein complex assembly	7.664605e-5
GO:0030324	lung development	7.706261e-5
GO:0043017	positive regulation of lymphotoxin A biosynthetic process	7.742104e-5
GO:0009893	positive regulation of metabolic process	7.782061e-5
GO:0002886	regulation of myeloid leukocyte mediated immunity	7.796258e-5
GO:0007005	mitochondrion organization	7.834377e-5
GO:0060485	mesenchyme development	7.894350e-5
GO:0002695	negative regulation of leukocyte activation	7.917765e-5
GO:0045859	regulation of protein kinase activity	8.059235e-5
GO:0001782	B cell homeostasis	8.090763e-5
GO:0034762	regulation of transmembrane transport	8.115778e-5
GO:0042596	fear response	8.165291e-5
GO:0051100	negative regulation of binding	8.228365e-5
GO:0051101	regulation of DNA binding	8.324791e-5
GO:0043301	negative regulation of leukocyte degranulation	8.459213e-5
GO:0006808	regulation of nitrogen utilization	8.570968e-5
GO:0042100	B cell proliferation	8.585125e-5
GO:0021999	neural plate anterior/posterior regionalization	9.052262e-5
GO:0032714	negative regulation of interleukin-5 production	9.052262e-5
GO:0050795	regulation of behavior	9.104399e-5
GO:2000021	regulation of ion homeostasis	9.168712e-5
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	9.411726e-5
GO:0032185	septin cytoskeleton organization	9.466949e-5
GO:0045869	negative regulation of retroviral genome replication	9.499423e-5
GO:0060662	salivary gland cavitation	9.602506e-5
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	9.650980e-5
GO:0051303	establishment of chromosome localization	9.675808e-5
GO:0048644	muscle organ morphogenesis	9.740993e-5
GO:0030091	protein repair	1.002170e-4
GO:0009584	detection of visible light	1.012502e-4
GO:0001654	eye development	1.014360e-4
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.018652e-4
GO:0045073	regulation of chemokine biosynthetic process	1.023947e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.048113e-4
GO:0071822	protein complex subunit organization	1.051793e-4
GO:0045080	positive regulation of chemokine biosynthetic process	1.078199e-4
GO:0042698	ovulation cycle	1.102338e-4
GO:0032696	negative regulation of interleukin-13 production	1.123489e-4
GO:0002699	positive regulation of immune effector process	1.146319e-4
GO:0048010	vascular endothelial growth factor receptor signaling pathway	1.149044e-4
GO:0050891	multicellular organismal water homeostasis	1.162530e-4
GO:0030003	cellular cation homeostasis	1.175068e-4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.204369e-4
GO:0048742	regulation of skeletal muscle fiber development	1.224811e-4
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.225498e-4
GO:0051656	establishment of organelle localization	1.235272e-4
GO:0071453	cellular response to oxygen levels	1.240478e-4
GO:0006325	chromatin organization	1.251244e-4
GO:0050778	positive regulation of immune response	1.268436e-4
GO:0021680	cerebellar Purkinje cell layer development	1.270564e-4
GO:0042157	lipoprotein metabolic process	1.275731e-4
GO:0051961	negative regulation of nervous system development	1.281824e-4
GO:0031669	cellular response to nutrient levels	1.296220e-4
GO:0048634	regulation of muscle organ development	1.328923e-4
GO:0002675	positive regulation of acute inflammatory response	1.332389e-4
GO:0009583	detection of light stimulus	1.354037e-4
GO:0034633	retinol transport	1.357787e-4
GO:0070613	regulation of protein processing	1.372977e-4
GO:0042127	regulation of cell proliferation	1.380124e-4
GO:0001970	positive regulation of activation of membrane attack complex	1.415311e-4
GO:0048592	eye morphogenesis	1.419808e-4
GO:0007584	response to nutrient	1.421837e-4
GO:0032642	regulation of chemokine production	1.438515e-4
GO:0008585	female gonad development	1.469521e-4
GO:0030323	respiratory tube development	1.473461e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.507182e-4
GO:0010043	response to zinc ion	1.511162e-4
GO:0090257	regulation of muscle system process	1.535191e-4
GO:0071276	cellular response to cadmium ion	1.535641e-4
GO:0030854	positive regulation of granulocyte differentiation	1.542790e-4
GO:0060415	muscle tissue morphogenesis	1.557416e-4
GO:0021678	third ventricle development	1.558026e-4
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.599081e-4
GO:0051549	positive regulation of keratinocyte migration	1.599081e-4
GO:0032990	cell part morphogenesis	1.602627e-4
GO:0034728	nucleosome organization	1.610497e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	1.615861e-4
GO:0009855	determination of bilateral symmetry	1.668530e-4
GO:0008543	fibroblast growth factor receptor signaling pathway	1.682589e-4
GO:0043589	skin morphogenesis	1.693557e-4
GO:0001542	ovulation from ovarian follicle	1.733705e-4
GO:0006656	phosphatidylcholine biosynthetic process	1.736386e-4
GO:0002819	regulation of adaptive immune response	1.795170e-4
GO:0032847	regulation of cellular pH reduction	1.799039e-4
GO:0085029	extracellular matrix assembly	1.818151e-4
GO:0002698	negative regulation of immune effector process	1.856405e-4
GO:0040030	regulation of molecular function, epigenetic	1.867969e-4
GO:0045575	basophil activation	1.867969e-4
GO:0001694	histamine biosynthetic process	1.867969e-4
GO:0050670	regulation of lymphocyte proliferation	1.873270e-4
GO:0003266	regulation of secondary heart field cardioblast proliferation	1.885440e-4
GO:0019933	cAMP-mediated signaling	1.910827e-4
GO:0031060	regulation of histone methylation	1.917495e-4
GO:0032101	regulation of response to external stimulus	1.934679e-4
GO:0007399	nervous system development	1.938032e-4
GO:0042993	positive regulation of transcription factor import into nucleus	1.961573e-4
GO:0009987	cellular process	2.017989e-4
GO:0009799	specification of symmetry	2.019931e-4
GO:0044092	negative regulation of molecular function	2.030227e-4
GO:0050920	regulation of chemotaxis	2.032536e-4
GO:0014888	striated muscle adaptation	2.038834e-4
GO:0001503	ossification	2.081926e-4
GO:0048660	regulation of smooth muscle cell proliferation	2.087551e-4
GO:0048251	elastic fiber assembly	2.123650e-4
GO:0050663	cytokine secretion	2.128514e-4
GO:0043206	fibril organization	2.144739e-4
GO:0045909	positive regulation of vasodilation	2.249007e-4
GO:0048858	cell projection morphogenesis	2.261006e-4
GO:0003211	cardiac ventricle formation	2.262907e-4
GO:0046668	regulation of retinal cell programmed cell death	2.302161e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.366409e-4
GO:0051336	regulation of hydrolase activity	2.408466e-4
GO:0035094	response to nicotine	2.441934e-4
GO:0061307	cardiac neural crest cell differentiation involved in heart development	2.499436e-4
GO:0022408	negative regulation of cell-cell adhesion	2.537535e-4
GO:0006911	phagocytosis, engulfment	2.544437e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.635921e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	2.647265e-4
GO:0009060	aerobic respiration	2.662762e-4
GO:0048741	skeletal muscle fiber development	2.683984e-4
GO:0000056	ribosomal small subunit export from nucleus	2.747683e-4
GO:0001957	intramembranous ossification	2.771693e-4
GO:0030279	negative regulation of ossification	2.784465e-4
GO:0010574	regulation of vascular endothelial growth factor production	2.823546e-4
GO:2000191	regulation of fatty acid transport	2.857311e-4
GO:0055008	cardiac muscle tissue morphogenesis	2.876231e-4
GO:0043030	regulation of macrophage activation	2.884463e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	2.916828e-4
GO:0035265	organ growth	3.094212e-4
GO:0030334	regulation of cell migration	3.178096e-4
GO:0010604	positive regulation of macromolecule metabolic process	3.178941e-4
GO:0051569	regulation of histone H3-K4 methylation	3.262317e-4
GO:0002673	regulation of acute inflammatory response	3.264046e-4
GO:0071173	spindle assembly checkpoint	3.276429e-4
GO:0032944	regulation of mononuclear cell proliferation	3.314429e-4
GO:0006873	cellular ion homeostasis	3.334416e-4
GO:0033689	negative regulation of osteoblast proliferation	3.413453e-4
GO:0071174	mitotic cell cycle spindle checkpoint	3.417210e-4
GO:0019079	viral genome replication	3.436185e-4
GO:0002921	negative regulation of humoral immune response	3.484509e-4
GO:0043461	proton-transporting ATP synthase complex assembly	3.524589e-4
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	3.528784e-4
GO:0060343	trabecula formation	3.555024e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0032849	positive regulation of cellular pH reduction	1.482120e-13
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.385015e-12
GO:0022417	protein maturation by protein folding	2.385015e-12
GO:0015670	carbon dioxide transport	3.374646e-12
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.714133e-11
GO:0009268	response to pH	2.117889e-10
GO:0032847	regulation of cellular pH reduction	3.489943e-10
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	4.331429e-10
GO:0006022	aminoglycan metabolic process	2.891326e-9
GO:0048844	artery morphogenesis	8.056061e-9
GO:0032501	multicellular organismal process	8.586549e-9
GO:0030157	pancreatic juice secretion	1.003288e-8
GO:0045844	positive regulation of striated muscle tissue development	1.113738e-8
GO:0048743	positive regulation of skeletal muscle fiber development	1.338205e-8
GO:0010957	negative regulation of vitamin D biosynthetic process	2.597905e-8
GO:0007586	digestion	3.411696e-8
GO:0048643	positive regulation of skeletal muscle tissue development	4.211556e-8
GO:0034337	RNA folding	4.766216e-8
GO:0006707	cholesterol catabolic process	4.766216e-8
GO:0030203	glycosaminoglycan metabolic process	4.857900e-8
GO:0060840	artery development	5.276916e-8
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.005273e-7
GO:0007517	muscle organ development	1.050950e-7
GO:0035909	aorta morphogenesis	1.131977e-7
GO:0044029	hypomethylation of CpG island	1.260105e-7
GO:0030204	chondroitin sulfate metabolic process	1.271321e-7
GO:0050896	response to stimulus	1.829521e-7
GO:0042036	negative regulation of cytokine biosynthetic process	2.124300e-7
GO:0035904	aorta development	2.829222e-7
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	3.627276e-7
GO:0009201	ribonucleoside triphosphate biosynthetic process	4.628654e-7
GO:0001974	blood vessel remodeling	5.016538e-7
GO:2000279	negative regulation of DNA biosynthetic process	5.450959e-7
GO:0006754	ATP biosynthetic process	6.087043e-7
GO:0010894	negative regulation of steroid biosynthetic process	7.658390e-7
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	9.069400e-7
GO:0034103	regulation of tissue remodeling	9.486580e-7
GO:0009145	purine nucleoside triphosphate biosynthetic process	9.869916e-7
GO:0006631	fatty acid metabolic process	9.952494e-7
GO:0009142	nucleoside triphosphate biosynthetic process	1.004090e-6
GO:0045780	positive regulation of bone resorption	1.034957e-6
GO:0032787	monocarboxylic acid metabolic process	1.169238e-6
GO:0034105	positive regulation of tissue remodeling	1.325603e-6
GO:0006029	proteoglycan metabolic process	1.414265e-6
GO:0009887	organ morphogenesis	1.456268e-6
GO:0018149	peptide cross-linking	1.618931e-6
GO:0051234	establishment of localization	1.894803e-6
GO:0006633	fatty acid biosynthetic process	1.999727e-6
GO:0022600	digestive system process	2.266861e-6
GO:0006810	transport	3.113588e-6
GO:0048513	organ development	3.447169e-6
GO:0048856	anatomical structure development	3.554757e-6
GO:0019408	dolichol biosynthetic process	3.862695e-6
GO:0008152	metabolic process	4.267742e-6
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	4.739735e-6
GO:0003008	system process	4.926648e-6
GO:0006706	steroid catabolic process	5.145582e-6
GO:0015860	purine nucleoside transport	5.413637e-6
GO:0045124	regulation of bone resorption	6.589648e-6
GO:0060986	endocrine hormone secretion	6.801982e-6
GO:0044255	cellular lipid metabolic process	8.145596e-6
GO:0002328	pro-B cell differentiation	8.241680e-6
GO:0042221	response to chemical stimulus	8.797218e-6
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	9.405158e-6
GO:0035910	ascending aorta morphogenesis	9.405158e-6
GO:0072530	purine-containing compound transmembrane transport	9.755206e-6
GO:0045751	negative regulation of Toll signaling pathway	9.909561e-6
GO:0090288	negative regulation of cellular response to growth factor stimulus	1.262215e-5
GO:0040019	positive regulation of embryonic development	1.442549e-5
GO:0032274	gonadotropin secretion	1.446212e-5
GO:0009152	purine ribonucleotide biosynthetic process	1.463609e-5
GO:0045746	negative regulation of Notch signaling pathway	1.822435e-5
GO:0019348	dolichol metabolic process	1.918009e-5
GO:0015669	gas transport	1.948680e-5
GO:0046850	regulation of bone remodeling	2.003946e-5
GO:0009653	anatomical structure morphogenesis	2.020615e-5
GO:0070563	negative regulation of vitamin D receptor signaling pathway	2.145121e-5
GO:2000647	negative regulation of stem cell proliferation	2.145121e-5
GO:0042851	L-alanine metabolic process	2.145121e-5
GO:0035921	desmosome disassembly	2.145121e-5
GO:0010839	negative regulation of keratinocyte proliferation	2.145121e-5
GO:0042180	cellular ketone metabolic process	2.404872e-5
GO:0006082	organic acid metabolic process	2.613981e-5
GO:0019752	carboxylic acid metabolic process	2.723696e-5
GO:0005976	polysaccharide metabolic process	2.943916e-5
GO:0046314	phosphocreatine biosynthetic process	3.174969e-5
GO:2000758	positive regulation of peptidyl-lysine acetylation	3.339962e-5
GO:0045670	regulation of osteoclast differentiation	4.250582e-5
GO:0048641	regulation of skeletal muscle tissue development	4.661769e-5
GO:0045672	positive regulation of osteoclast differentiation	5.387608e-5
GO:2000278	regulation of DNA biosynthetic process	5.578184e-5
GO:0045081	negative regulation of interleukin-10 biosynthetic process	5.786398e-5
GO:0046514	ceramide catabolic process	5.804136e-5
GO:0021522	spinal cord motor neuron differentiation	5.845564e-5
GO:0048742	regulation of skeletal muscle fiber development	5.924505e-5
GO:0048731	system development	6.362497e-5
GO:0042759	long-chain fatty acid biosynthetic process	6.415637e-5
GO:0045409	negative regulation of interleukin-6 biosynthetic process	6.570298e-5
GO:0042752	regulation of circadian rhythm	6.850607e-5
GO:0035108	limb morphogenesis	7.113755e-5
GO:0044030	regulation of DNA methylation	7.149463e-5
GO:0045128	negative regulation of reciprocal meiotic recombination	7.197055e-5
GO:0006311	meiotic gene conversion	7.197055e-5
GO:0006467	protein thiol-disulfide exchange	7.406349e-5
GO:0003209	cardiac atrium morphogenesis	8.002573e-5
GO:0006198	cAMP catabolic process	8.175749e-5
GO:0060556	regulation of vitamin D biosynthetic process	8.975403e-5
GO:0043048	dolichyl monophosphate biosynthetic process	9.533180e-5
GO:0070562	regulation of vitamin D receptor signaling pathway	9.601479e-5
GO:0016525	negative regulation of angiogenesis	9.656429e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	9.811207e-5
GO:0007275	multicellular organismal development	9.886445e-5
GO:0048771	tissue remodeling	9.930685e-5
GO:0048729	tissue morphogenesis	9.956435e-5
GO:0060173	limb development	1.007029e-4
GO:0006629	lipid metabolic process	1.017470e-4
GO:0009260	ribonucleotide biosynthetic process	1.047916e-4
GO:0045835	negative regulation of meiosis	1.065922e-4
GO:0009888	tissue development	1.168034e-4
GO:0002344	B cell affinity maturation	1.181853e-4
GO:0032502	developmental process	1.240651e-4
GO:0035964	COPI-coated vesicle budding	1.262080e-4
GO:0060972	left/right pattern formation	1.415391e-4
GO:0002339	B cell selection	1.415391e-4
GO:0046826	negative regulation of protein export from nucleus	1.489618e-4
GO:0044238	primary metabolic process	1.579090e-4
GO:0032846	positive regulation of homeostatic process	1.652960e-4
GO:0009308	amine metabolic process	1.676953e-4
GO:0021515	cell differentiation in spinal cord	1.678769e-4
GO:0050906	detection of stimulus involved in sensory perception	1.726473e-4
GO:0008593	regulation of Notch signaling pathway	1.746061e-4
GO:0007155	cell adhesion	1.813545e-4
GO:0045814	negative regulation of gene expression, epigenetic	1.944798e-4
GO:0022610	biological adhesion	1.987933e-4
GO:0051640	organelle localization	2.027280e-4
GO:0031953	negative regulation of protein autophosphorylation	2.111728e-4
GO:0051093	negative regulation of developmental process	2.155390e-4
GO:0010288	response to lead ion	2.164167e-4
GO:0046394	carboxylic acid biosynthetic process	2.233750e-4
GO:0070585	protein localization in mitochondrion	2.285545e-4
GO:0045595	regulation of cell differentiation	2.672655e-4
GO:0015858	nucleoside transport	2.725411e-4
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	2.811375e-4
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	2.811375e-4
GO:2000756	regulation of peptidyl-lysine acetylation	3.067674e-4
GO:0007608	sensory perception of smell	3.072045e-4
GO:0003289	atrial septum primum morphogenesis	3.110119e-4
GO:0072001	renal system development	3.196261e-4
GO:0003230	cardiac atrium development	3.238859e-4
GO:0051659	maintenance of mitochondrion location	3.333915e-4
GO:0007519	skeletal muscle tissue development	3.374743e-4
GO:0001655	urogenital system development	3.416232e-4
GO:0048704	embryonic skeletal system morphogenesis	3.554586e-4
GO:0070869	heterochromatin formation involved in chromatin silencing	3.590334e-4
GO:0072274	metanephric glomerular basement membrane development	3.682670e-4
GO:0072249	metanephric glomerular visceral epithelial cell development	3.682670e-4
GO:0048677	axon extension involved in regeneration	3.682670e-4
GO:0051646	mitochondrion localization	3.737823e-4
GO:0021510	spinal cord development	3.764555e-4
GO:0034374	low-density lipoprotein particle remodeling	3.846459e-4
GO:0044242	cellular lipid catabolic process	4.050385e-4
GO:0007165	signal transduction	4.055100e-4
GO:0030330	DNA damage response, signal transduction by p53 class mediator	4.112304e-4
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	4.127881e-4
GO:0048644	muscle organ morphogenesis	4.309469e-4
GO:0010817	regulation of hormone levels	4.463810e-4
GO:0001501	skeletal system development	4.569191e-4
GO:0016576	histone dephosphorylation	4.663460e-4
GO:0048343	paraxial mesodermal cell fate commitment	4.670187e-4
GO:0014049	positive regulation of glutamate secretion	4.696465e-4
GO:0032728	positive regulation of interferon-beta production	4.779499e-4
GO:0060538	skeletal muscle organ development	4.798575e-4
GO:0051155	positive regulation of striated muscle cell differentiation	4.894357e-4
GO:0051657	maintenance of organelle location	4.944602e-4
GO:0044283	small molecule biosynthetic process	5.269441e-4
GO:0051149	positive regulation of muscle cell differentiation	5.280000e-4
GO:0016042	lipid catabolic process	5.320631e-4
GO:0044281	small molecule metabolic process	5.402147e-4
GO:0007589	body fluid secretion	5.452889e-4
GO:0060631	regulation of meiosis I	5.531604e-4
GO:0010033	response to organic substance	5.584922e-4
GO:0060563	neuroepithelial cell differentiation	5.587896e-4
GO:0050886	endocrine process	5.814647e-4
GO:0009395	phospholipid catabolic process	5.816108e-4
GO:0009914	hormone transport	6.151462e-4
GO:0048311	mitochondrion distribution	6.202203e-4
GO:0001822	kidney development	6.246987e-4
GO:0007606	sensory perception of chemical stimulus	6.349849e-4
GO:0046879	hormone secretion	6.452172e-4
GO:0060537	muscle tissue development	6.725867e-4
GO:0046466	membrane lipid catabolic process	6.798241e-4
GO:0021516	dorsal spinal cord development	6.798241e-4
GO:0007229	integrin-mediated signaling pathway	6.938463e-4
GO:0044237	cellular metabolic process	6.980904e-4
GO:0032321	positive regulation of Rho GTPase activity	7.091326e-4
GO:0046689	response to mercury ion	7.149310e-4
GO:0002064	epithelial cell development	7.187418e-4
GO:0006643	membrane lipid metabolic process	7.217259e-4
GO:0009214	cyclic nucleotide catabolic process	7.222931e-4
GO:0010042	response to manganese ion	7.302208e-4
GO:0048199	vesicle targeting, to, from or within Golgi	7.659187e-4
GO:0035786	protein complex oligomerization	7.745937e-4
GO:0002009	morphogenesis of an epithelium	8.196456e-4
GO:0001736	establishment of planar polarity	8.818097e-4
GO:0044241	lipid digestion	8.860336e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	8.995623e-4
GO:0010232	vascular transport	9.468155e-4
GO:0021782	glial cell development	1.006830e-3
GO:0045187	regulation of circadian sleep/wake cycle, sleep	1.027409e-3
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	1.032289e-3
GO:0080134	regulation of response to stress	1.042806e-3
GO:0048512	circadian behavior	1.056145e-3
GO:0050711	negative regulation of interleukin-1 secretion	1.060819e-3
GO:0035295	tube development	1.069613e-3
GO:0042769	DNA damage response, detection of DNA damage	1.073724e-3
GO:0010043	response to zinc ion	1.101244e-3
GO:0001516	prostaglandin biosynthetic process	1.108459e-3
GO:0051239	regulation of multicellular organismal process	1.144025e-3
GO:0006665	sphingolipid metabolic process	1.150608e-3
GO:0003357	noradrenergic neuron differentiation	1.159892e-3
GO:0032692	negative regulation of interleukin-1 production	1.187431e-3
GO:0051179	localization	1.193466e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	1.203548e-3
GO:0015867	ATP transport	1.203548e-3
GO:0015868	purine ribonucleotide transport	1.205342e-3
GO:0018209	peptidyl-serine modification	1.209780e-3
GO:0048539	bone marrow development	1.271645e-3
GO:0060312	regulation of blood vessel remodeling	1.271645e-3
GO:0010520	regulation of reciprocal meiotic recombination	1.271645e-3
GO:0060413	atrial septum morphogenesis	1.273089e-3
GO:0001967	suckling behavior	1.273089e-3
GO:0060426	lung vasculature development	1.302537e-3
GO:0023052	signaling	1.314747e-3
GO:0042060	wound healing	1.339624e-3
GO:0030149	sphingolipid catabolic process	1.349757e-3
GO:0016090	prenol metabolic process	1.365338e-3
GO:0010038	response to metal ion	1.366766e-3
GO:0000710	meiotic mismatch repair	1.387044e-3
GO:0061061	muscle structure development	1.420273e-3
GO:0006603	phosphocreatine metabolic process	1.432646e-3
GO:0046903	secretion	1.466502e-3
GO:0040020	regulation of meiosis	1.490250e-3
GO:0006705	mineralocorticoid biosynthetic process	1.497904e-3
GO:2000026	regulation of multicellular organismal development	1.517374e-3
GO:0044243	multicellular organismal catabolic process	1.544836e-3
GO:0007164	establishment of tissue polarity	1.571575e-3
GO:0046549	retinal cone cell development	1.577874e-3
GO:0051147	regulation of muscle cell differentiation	1.678552e-3
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	1.682986e-3
GO:0003183	mitral valve morphogenesis	1.682986e-3
GO:0045989	positive regulation of striated muscle contraction	1.707647e-3
GO:0010519	negative regulation of phospholipase activity	1.730715e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	1.737129e-3
GO:0046034	ATP metabolic process	1.775305e-3
GO:0001710	mesodermal cell fate commitment	1.780136e-3
GO:0001676	long-chain fatty acid metabolic process	1.795406e-3
GO:0022010	central nervous system myelination	1.808275e-3
GO:0032808	lacrimal gland development	1.860595e-3
GO:0060415	muscle tissue morphogenesis	1.898238e-3
GO:0000132	establishment of mitotic spindle orientation	1.926703e-3
GO:0045596	negative regulation of cell differentiation	1.927064e-3
GO:0002763	positive regulation of myeloid leukocyte differentiation	1.942882e-3
GO:0032025	response to cobalt ion	1.950171e-3
GO:0045637	regulation of myeloid cell differentiation	2.033056e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	2.043356e-3
GO:0051096	positive regulation of helicase activity	2.043533e-3
GO:0015893	drug transport	2.082243e-3
GO:0010350	cellular response to magnesium starvation	2.088251e-3
GO:0001503	ossification	2.112694e-3
GO:0006626	protein targeting to mitochondrion	2.134841e-3
GO:0031016	pancreas development	2.150351e-3
GO:0030263	apoptotic chromosome condensation	2.186688e-3
GO:0001913	T cell mediated cytotoxicity	2.186688e-3
GO:0072560	type B pancreatic cell maturation	2.231738e-3
GO:0009987	cellular process	2.243497e-3
GO:0051173	positive regulation of nitrogen compound metabolic process	2.289334e-3
GO:0042632	cholesterol homeostasis	2.329870e-3
GO:0042745	circadian sleep/wake cycle	2.330499e-3
GO:0006693	prostaglandin metabolic process	2.330499e-3
GO:0046541	saliva secretion	2.382417e-3
GO:0002761	regulation of myeloid leukocyte differentiation	2.409078e-3
GO:0007166	cell surface receptor linked signaling pathway	2.436736e-3
GO:0043570	maintenance of DNA repeat elements	2.440235e-3
GO:0072655	establishment of protein localization in mitochondrion	2.443531e-3
GO:0048333	mesodermal cell differentiation	2.464477e-3
GO:0007154	cell communication	2.468136e-3
GO:0060021	palate development	2.523864e-3
GO:0051445	regulation of meiotic cell cycle	2.539154e-3
GO:0031529	ruffle organization	2.573077e-3
GO:0030900	forebrain development	2.603899e-3
GO:0043009	chordate embryonic development	2.614174e-3
GO:0051224	negative regulation of protein transport	2.626780e-3
GO:0009790	embryo development	2.650069e-3
GO:0040001	establishment of mitotic spindle localization	2.666597e-3
GO:0060429	epithelium development	2.705804e-3
GO:0006851	mitochondrial calcium ion transport	2.724234e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.734102e-3
GO:0050793	regulation of developmental process	2.771234e-3
GO:0071383	cellular response to steroid hormone stimulus	2.789924e-3
GO:0010720	positive regulation of cell development	2.884110e-3
GO:0015939	pantothenate metabolic process	2.903923e-3
GO:0009125	nucleoside monophosphate catabolic process	2.913926e-3
GO:0042396	phosphagen biosynthetic process	2.947915e-3
GO:0021520	spinal cord motor neuron cell fate specification	2.949028e-3
GO:0051153	regulation of striated muscle cell differentiation	2.952617e-3
GO:0042938	dipeptide transport	3.011978e-3
GO:0007622	rhythmic behavior	3.069576e-3
GO:2001021	negative regulation of response to DNA damage stimulus	3.074464e-3
GO:0072331	signal transduction by p53 class mediator	3.115773e-3
GO:0032648	regulation of interferon-beta production	3.118279e-3
GO:0045639	positive regulation of myeloid cell differentiation	3.120352e-3
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	3.180424e-3
GO:0050974	detection of mechanical stimulus involved in sensory perception	3.204871e-3
GO:0014706	striated muscle tissue development	3.234480e-3
GO:0009225	nucleotide-sugar metabolic process	3.259367e-3
GO:0051606	detection of stimulus	3.317693e-3
GO:0060632	regulation of microtubule-based movement	3.353123e-3
GO:0060414	aorta smooth muscle tissue morphogenesis	3.353123e-3
GO:0042770	signal transduction in response to DNA damage	3.362689e-3
GO:0016925	protein sumoylation	3.398851e-3
GO:0051094	positive regulation of developmental process	3.404077e-3
GO:0048935	peripheral nervous system neuron development	3.414662e-3
GO:0014045	establishment of endothelial blood-brain barrier	3.486921e-3
GO:0061028	establishment of endothelial barrier	3.545744e-3
GO:0031018	endocrine pancreas development	3.561780e-3
GO:0051095	regulation of helicase activity	3.583744e-3
GO:0009611	response to wounding	3.586714e-3
GO:0046825	regulation of protein export from nucleus	3.594992e-3
GO:0070206	protein trimerization	3.613790e-3
GO:0021517	ventral spinal cord development	3.662948e-3
GO:0007156	homophilic cell adhesion	3.782530e-3
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	3.782746e-3
GO:0022410	circadian sleep/wake cycle process	3.845702e-3
GO:0014009	glial cell proliferation	3.850710e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	4.020032e-3
GO:0021796	cerebral cortex regionalization	4.047544e-3
GO:0042891	antibiotic transport	4.075590e-3
GO:0032231	regulation of actin filament bundle assembly	4.084111e-3
GO:0045932	negative regulation of muscle contraction	4.376765e-3
GO:0051036	regulation of endosome size	4.488663e-3
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	4.488663e-3
GO:0019428	allantoin biosynthetic process	4.488663e-3
GO:0006790	sulfur compound metabolic process	4.553799e-3
GO:0045597	positive regulation of cell differentiation	4.619381e-3
GO:0048665	neuron fate specification	4.771642e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.791721e-3
GO:0009792	embryo development ending in birth or egg hatching	4.896956e-3
GO:0051053	negative regulation of DNA metabolic process	4.929717e-3
GO:0006164	purine nucleotide biosynthetic process	4.939361e-3
GO:0001937	negative regulation of endothelial cell proliferation	4.998687e-3
GO:0007417	central nervous system development	5.009419e-3
GO:0048514	blood vessel morphogenesis	5.149140e-3
GO:0023061	signal release	5.185213e-3
GO:0090317	negative regulation of intracellular protein transport	5.234476e-3
GO:0090076	relaxation of skeletal muscle	5.235382e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	5.235382e-3
GO:0043313	regulation of neutrophil degranulation	5.235382e-3
GO:0006301	postreplication repair	5.356838e-3
GO:0051293	establishment of spindle localization	5.374701e-3
GO:0070541	response to platinum ion	5.399536e-3
GO:0045039	protein import into mitochondrial inner membrane	5.424019e-3
GO:0010001	glial cell differentiation	5.448531e-3
GO:0002827	positive regulation of T-helper 1 type immune response	5.448650e-3
GO:0009628	response to abiotic stimulus	5.500346e-3
GO:0009267	cellular response to starvation	5.513013e-3
GO:0042448	progesterone metabolic process	5.650390e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.650390e-3
GO:0009100	glycoprotein metabolic process	5.673216e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	5.704240e-3
GO:0046381	CMP-N-acetylneuraminate metabolic process	5.803598e-3
GO:0060577	pulmonary vein morphogenesis	5.847581e-3
GO:0006030	chitin metabolic process	5.878281e-3
GO:0001561	fatty acid alpha-oxidation	5.878281e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.890897e-3
GO:0032481	positive regulation of type I interferon production	5.908485e-3
GO:0007076	mitotic chromosome condensation	6.038212e-3
GO:0002577	regulation of antigen processing and presentation	6.068044e-3
GO:0032319	regulation of Rho GTPase activity	6.126577e-3
GO:0032094	response to food	6.258173e-3
GO:0046415	urate metabolic process	6.302262e-3
GO:0045408	regulation of interleukin-6 biosynthetic process	6.302262e-3
GO:0046456	icosanoid biosynthetic process	6.323107e-3
GO:0045214	sarcomere organization	6.330377e-3
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	6.418064e-3
GO:0001542	ovulation from ovarian follicle	6.435247e-3
GO:0031573	intra-S DNA damage checkpoint	6.592650e-3
GO:0005975	carbohydrate metabolic process	6.700819e-3
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	6.745700e-3
GO:0048518	positive regulation of biological process	6.759314e-3
GO:0045671	negative regulation of osteoclast differentiation	6.831060e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	6.889874e-3
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	6.910537e-3
GO:0060174	limb bud formation	6.922655e-3
GO:0035023	regulation of Rho protein signal transduction	6.956953e-3
GO:0006839	mitochondrial transport	6.963175e-3
GO:0034113	heterotypic cell-cell adhesion	6.994973e-3
GO:0003323	type B pancreatic cell development	7.079324e-3
GO:0014034	neural crest cell fate commitment	7.114542e-3
GO:0050982	detection of mechanical stimulus	7.189862e-3
GO:0034605	cellular response to heat	7.228152e-3
GO:0001837	epithelial to mesenchymal transition	7.312670e-3
GO:0034097	response to cytokine stimulus	7.356069e-3
GO:0010447	response to acidity	7.369539e-3
GO:0035239	tube morphogenesis	7.541286e-3
GO:0007512	adult heart development	7.552775e-3
GO:0001708	cell fate specification	7.576100e-3
GO:0031328	positive regulation of cellular biosynthetic process	7.611683e-3
GO:0003170	heart valve development	7.788008e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	7.811897e-3
GO:0003007	heart morphogenesis	7.867625e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	7.890945e-3
GO:0055114	oxidation-reduction process	7.947333e-3
GO:0048710	regulation of astrocyte differentiation	7.953871e-3
GO:0090141	positive regulation of mitochondrial fission	7.956857e-3
GO:0000114	regulation of transcription involved in G1 phase of mitotic cell cycle	7.956857e-3
GO:0060578	superior vena cava morphogenesis	7.956857e-3
GO:0001738	morphogenesis of a polarized epithelium	8.088642e-3
GO:0010628	positive regulation of gene expression	8.185511e-3
GO:0016446	somatic hypermutation of immunoglobulin genes	8.436103e-3
GO:0071333	cellular response to glucose stimulus	8.580163e-3
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	8.580857e-3
GO:0060284	regulation of cell development	8.730891e-3
GO:0006457	protein folding	8.772848e-3
GO:0060525	prostate glandular acinus development	8.978426e-3
GO:0014063	negative regulation of serotonin secretion	8.979387e-3
GO:0048642	negative regulation of skeletal muscle tissue development	8.985874e-3
GO:0045988	negative regulation of striated muscle contraction	9.122935e-3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	9.123339e-3
GO:0045722	positive regulation of gluconeogenesis	9.123339e-3
GO:0003341	cilium movement	9.155997e-3
GO:0030299	intestinal cholesterol absorption	9.159136e-3
GO:0003283	atrial septum development	9.218643e-3
GO:0006636	unsaturated fatty acid biosynthetic process	9.325205e-3
GO:0010524	positive regulation of calcium ion transport into cytosol	9.353000e-3
GO:0090140	regulation of mitochondrial fission	9.719090e-3
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	9.719090e-3
GO:0007399	nervous system development	9.732018e-3
GO:0051051	negative regulation of transport	9.754443e-3
GO:0035270	endocrine system development	9.756721e-3
GO:0051656	establishment of organelle localization	9.851457e-3
GO:0001946	lymphangiogenesis	9.928029e-3
GO:0048598	embryonic morphogenesis	1.013542e-2
GO:0030001	metal ion transport	1.015561e-2
GO:0008207	C21-steroid hormone metabolic process	1.024564e-2
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.025101e-2
GO:0007501	mesodermal cell fate specification	1.025101e-2
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	1.031961e-2
GO:0010815	bradykinin catabolic process	1.031961e-2
GO:0001678	cellular glucose homeostasis	1.035789e-2
GO:0030031	cell projection assembly	1.039724e-2
GO:0060562	epithelial tube morphogenesis	1.050755e-2
GO:0032107	regulation of response to nutrient levels	1.073665e-2
GO:0001778	plasma membrane repair	1.074451e-2
GO:0046069	cGMP catabolic process	1.074451e-2
GO:0055085	transmembrane transport	1.081706e-2
GO:0060285	ciliary cell motility	1.089507e-2
GO:0010963	regulation of L-arginine import	1.089507e-2
GO:0008610	lipid biosynthetic process	1.090150e-2
GO:0051716	cellular response to stimulus	1.093183e-2
GO:0009056	catabolic process	1.106262e-2
GO:0030252	growth hormone secretion	1.116445e-2
GO:0016337	cell-cell adhesion	1.126979e-2
GO:0051602	response to electrical stimulus	1.149942e-2
GO:0032479	regulation of type I interferon production	1.161978e-2
GO:0032026	response to magnesium ion	1.174879e-2
GO:0043403	skeletal muscle tissue regeneration	1.177010e-2
GO:0034474	U2 snRNA 3'-end processing	1.177378e-2
GO:0090241	negative regulation of histone H4 acetylation	1.177378e-2
GO:0034401	regulation of transcription by chromatin organization	1.177378e-2
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	1.193093e-2
GO:0043420	anthranilate metabolic process	1.193093e-2
GO:0034516	response to vitamin B6	1.193093e-2
GO:0030522	intracellular receptor mediated signaling pathway	1.202900e-2
GO:0035264	multicellular organism growth	1.206926e-2
GO:0051567	histone H3-K9 methylation	1.218307e-2
GO:0001547	antral ovarian follicle growth	1.218307e-2
GO:0010738	regulation of protein kinase A signaling cascade	1.221342e-2
GO:0046847	filopodium assembly	1.238885e-2
GO:0045541	negative regulation of cholesterol biosynthetic process	1.251136e-2
GO:0006787	porphyrin-containing compound catabolic process	1.251136e-2
GO:0006690	icosanoid metabolic process	1.276301e-2
GO:0032108	negative regulation of response to nutrient levels	1.284225e-2
GO:0046823	negative regulation of nucleocytoplasmic transport	1.286406e-2
GO:0032856	activation of Ras GTPase activity	1.289138e-2
GO:0030728	ovulation	1.318511e-2
GO:0022009	central nervous system vasculogenesis	1.324348e-2
GO:0032488	Cdc42 protein signal transduction	1.349668e-2
GO:0003347	epicardial cell to mesenchymal cell transition	1.351717e-2
GO:0045765	regulation of angiogenesis	1.357652e-2
GO:0045995	regulation of embryonic development	1.389523e-2
GO:0051089	constitutive protein ectodomain proteolysis	1.395842e-2
GO:0070836	caveola assembly	1.395842e-2
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	1.395842e-2
GO:0019240	citrulline biosynthetic process	1.395842e-2
GO:0048583	regulation of response to stimulus	1.399750e-2
GO:0050907	detection of chemical stimulus involved in sensory perception	1.429607e-2
GO:0051705	behavioral interaction between organisms	1.442662e-2
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	1.443401e-2
GO:0003272	endocardial cushion formation	1.452069e-2
GO:0043501	skeletal muscle adaptation	1.453701e-2