Novel motif:106

name:	motif106_KCGCANTC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006396	RNA processing	6.507231e-16
GO:0006281	DNA repair	2.408997e-15
GO:0000389	nuclear mRNA 3'-splice site recognition	7.536976e-13
GO:0006370	mRNA capping	1.397424e-11
GO:0009452	RNA capping	1.811991e-10
GO:0032864	activation of Cdc42 GTPase activity	3.078338e-9
GO:0032790	ribosome disassembly	2.070835e-8
GO:0034470	ncRNA processing	2.766654e-8
GO:0045963	negative regulation of dopamine metabolic process	5.314833e-8
GO:0050668	positive regulation of homocysteine metabolic process	5.314833e-8
GO:0006368	transcription elongation from RNA polymerase II promoter	1.240428e-7
GO:0006397	mRNA processing	2.346190e-7
GO:0031104	dendrite regeneration	4.467243e-7
GO:0019087	transformation of host cell by virus	5.239174e-7
GO:0050434	positive regulation of viral transcription	5.823391e-7
GO:0090162	establishment of epithelial cell polarity	7.105871e-7
GO:0016071	mRNA metabolic process	7.526937e-7
GO:0050666	regulation of homocysteine metabolic process	8.805431e-7
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.056846e-6
GO:0000724	double-strand break repair via homologous recombination	1.175005e-6
GO:0001510	RNA methylation	1.529775e-6
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.794302e-6
GO:0000725	recombinational repair	1.861105e-6
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.118440e-6
GO:0000416	positive regulation of histone H3-K36 methylation	2.409552e-6
GO:0018872	arsonoacetate metabolic process	2.694815e-6
GO:0051102	DNA ligation involved in DNA recombination	2.694815e-6
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	2.694815e-6
GO:0008033	tRNA processing	2.977027e-6
GO:0070534	protein K63-linked ubiquitination	3.079644e-6
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3.216020e-6
GO:0009451	RNA modification	4.014860e-6
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	4.108674e-6
GO:0006391	transcription initiation from mitochondrial promoter	4.949118e-6
GO:0006974	response to DNA damage stimulus	6.123478e-6
GO:0034080	CenH3-containing nucleosome assembly at centromere	6.873519e-6
GO:0006354	transcription elongation, DNA-dependent	7.651184e-6
GO:0061014	positive regulation of mRNA catabolic process	7.749167e-6
GO:0043089	positive regulation of Cdc42 GTPase activity	7.886190e-6
GO:0035356	cellular triglyceride homeostasis	8.491317e-6
GO:0007181	transforming growth factor beta receptor complex assembly	1.000575e-5
GO:0001514	selenocysteine incorporation	1.022695e-5
GO:0048702	embryonic neurocranium morphogenesis	1.052165e-5
GO:0046940	nucleoside monophosphate phosphorylation	1.131149e-5
GO:0033119	negative regulation of RNA splicing	1.348097e-5
GO:0010912	positive regulation of isomerase activity	1.372034e-5
GO:0032988	ribonucleoprotein complex disassembly	1.655392e-5
GO:0006298	mismatch repair	1.683263e-5
GO:0071044	histone mRNA catabolic process	1.719287e-5
GO:0021754	facial nucleus development	2.053428e-5
GO:0040032	post-embryonic body morphogenesis	2.264906e-5
GO:0061157	mRNA destabilization	2.313113e-5
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	2.313113e-5
GO:0021903	rostrocaudal neural tube patterning	2.482206e-5
GO:0006310	DNA recombination	2.766694e-5
GO:0061090	positive regulation of sequestering of zinc ion	2.778101e-5
GO:0031119	tRNA pseudouridine synthesis	2.778101e-5
GO:0033233	regulation of protein sumoylation	2.866160e-5
GO:0090307	spindle assembly involved in mitosis	2.912711e-5
GO:0000422	mitochondrion degradation	3.405611e-5
GO:0006119	oxidative phosphorylation	3.415342e-5
GO:0031055	chromatin remodeling at centromere	3.490967e-5
GO:0060381	positive regulation of single-stranded telomeric DNA binding	3.498477e-5
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	3.848707e-5
GO:0033084	regulation of immature T cell proliferation in thymus	3.965458e-5
GO:0007051	spindle organization	4.166269e-5
GO:0021612	facial nerve structural organization	4.836700e-5
GO:0016482	cytoplasmic transport	5.374615e-5
GO:0016578	histone deubiquitination	5.556550e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	5.743819e-5
GO:0046607	positive regulation of centrosome cycle	5.807816e-5
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	6.017279e-5
GO:0033108	mitochondrial respiratory chain complex assembly	6.277170e-5
GO:0043486	histone exchange	6.340455e-5
GO:0070980	biphenyl catabolic process	6.793132e-5
GO:0052697	xenobiotic glucuronidation	6.793132e-5
GO:0006789	bilirubin conjugation	6.793132e-5
GO:0051552	flavone metabolic process	6.793132e-5
GO:0052696	flavonoid glucuronidation	6.793132e-5
GO:0051571	positive regulation of histone H3-K4 methylation	6.935537e-5
GO:0033239	negative regulation of cellular amine metabolic process	6.954815e-5
GO:0006412	translation	7.438535e-5
GO:0048790	maintenance of presynaptic active zone structure	7.996185e-5
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	7.996185e-5
GO:0006400	tRNA modification	8.032641e-5
GO:0043484	regulation of RNA splicing	8.641593e-5
GO:0006302	double-strand break repair	8.998678e-5
GO:0043471	regulation of cellular carbohydrate catabolic process	9.678006e-5
GO:0043414	macromolecule methylation	9.799772e-5
GO:0030262	apoptotic nuclear change	9.881172e-5
GO:0048486	parasympathetic nervous system development	1.144782e-4
GO:0060179	male mating behavior	1.164735e-4
GO:0021571	rhombomere 5 development	1.198766e-4
GO:0032259	methylation	1.258443e-4
GO:0046502	uroporphyrinogen III metabolic process	1.302672e-4
GO:0010172	embryonic body morphogenesis	1.317543e-4
GO:0000154	rRNA modification	1.321758e-4
GO:0006054	N-acetylneuraminate metabolic process	1.338810e-4
GO:0008380	RNA splicing	1.357454e-4
GO:0006289	nucleotide-excision repair	1.367596e-4
GO:0008298	intracellular mRNA localization	1.479465e-4
GO:0043088	regulation of Cdc42 GTPase activity	1.548918e-4
GO:0030683	evasion by virus of host immune response	1.645466e-4
GO:0045198	establishment of epithelial cell apical/basal polarity	1.700453e-4
GO:0071460	cellular response to cell-matrix adhesion	1.886571e-4
GO:0051089	constitutive protein ectodomain proteolysis	1.936822e-4
GO:0085020	protein K6-linked ubiquitination	1.955059e-4
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.064557e-4
GO:0060461	right lung morphogenesis	2.096521e-4
GO:0090131	mesenchyme migration	2.096521e-4
GO:0014822	detection of wounding	2.096521e-4
GO:0060446	branching involved in open tracheal system development	2.096521e-4
GO:0048613	embryonic ectodermal digestive tract morphogenesis	2.096521e-4
GO:0048371	lateral mesodermal cell differentiation	2.096521e-4
GO:0008210	estrogen metabolic process	2.106461e-4
GO:0006284	base-excision repair	2.356742e-4
GO:0051225	spindle assembly	2.359835e-4
GO:0000375	RNA splicing, via transesterification reactions	2.489395e-4
GO:0031297	replication fork processing	2.586730e-4
GO:0035519	protein K29-linked ubiquitination	2.616728e-4
GO:0016567	protein ubiquitination	3.113832e-4
GO:0018277	protein deamination	3.152758e-4
GO:0045007	depurination	3.152758e-4
GO:0042069	regulation of catecholamine metabolic process	3.175741e-4
GO:0051567	histone H3-K9 methylation	3.188084e-4
GO:0009048	dosage compensation, by inactivation of X chromosome	3.222634e-4
GO:0044265	cellular macromolecule catabolic process	3.351489e-4
GO:0061013	regulation of mRNA catabolic process	3.359646e-4
GO:0006780	uroporphyrinogen III biosynthetic process	3.385320e-4
GO:0021783	preganglionic parasympathetic nervous system development	3.395387e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	3.503358e-4
GO:0042699	follicle-stimulating hormone signaling pathway	3.626469e-4
GO:0090149	membrane fission involved in mitochondrial fission	3.700756e-4
GO:0070625	zymogen granule exocytosis	3.700756e-4
GO:0003374	dynamin polymerization involved in mitochondrial fission	3.700756e-4
GO:0046604	positive regulation of mitotic centrosome separation	3.700756e-4
GO:0016032	viral reproduction	3.722379e-4
GO:0000266	mitochondrial fission	3.760980e-4
GO:0006308	DNA catabolic process	3.827315e-4
GO:0080009	mRNA methylation	3.902241e-4
GO:0008049	male courtship behavior	3.902241e-4
GO:0006285	base-excision repair, AP site formation	4.010963e-4
GO:0034660	ncRNA metabolic process	4.059521e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	4.086134e-4
GO:0009265	2'-deoxyribonucleotide biosynthetic process	4.094424e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	4.145675e-4
GO:0033235	positive regulation of protein sumoylation	4.245977e-4
GO:0042776	mitochondrial ATP synthesis coupled proton transport	4.258550e-4
GO:0016072	rRNA metabolic process	4.464467e-4
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	4.623389e-4
GO:0051645	Golgi localization	4.698609e-4
GO:0006432	phenylalanyl-tRNA aminoacylation	4.698609e-4
GO:0006363	termination of RNA polymerase I transcription	4.719357e-4
GO:0009133	nucleoside diphosphate biosynthetic process	4.821968e-4
GO:0006413	translational initiation	4.959945e-4
GO:0006352	transcription initiation, DNA-dependent	5.001368e-4
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	5.112222e-4
GO:0046782	regulation of viral transcription	5.198901e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	5.245309e-4
GO:0000022	mitotic spindle elongation	5.397390e-4
GO:0033083	regulation of immature T cell proliferation	5.539816e-4
GO:0043044	ATP-dependent chromatin remodeling	6.292123e-4
GO:0051301	cell division	6.333480e-4
GO:0046605	regulation of centrosome cycle	6.360649e-4
GO:0006364	rRNA processing	6.555149e-4
GO:0043467	regulation of generation of precursor metabolites and energy	7.194925e-4
GO:0021610	facial nerve morphogenesis	7.250985e-4
GO:0006172	ADP biosynthetic process	7.322024e-4
GO:0015742	alpha-ketoglutarate transport	7.353015e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	7.392196e-4
GO:0010467	gene expression	7.451951e-4
GO:0021569	rhombomere 3 development	7.693728e-4
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.787043e-4
GO:0000731	DNA synthesis involved in DNA repair	7.842565e-4
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	7.842565e-4
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	7.844888e-4
GO:0090304	nucleic acid metabolic process	8.155910e-4
GO:0046939	nucleotide phosphorylation	8.276019e-4
GO:0046341	CDP-diacylglycerol metabolic process	8.463778e-4
GO:0042664	negative regulation of endodermal cell fate specification	8.770254e-4
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	8.770254e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	8.770254e-4
GO:0060975	cardioblast migration to the midline involved in heart field formation	8.770254e-4
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	8.770254e-4
GO:0060921	sinoatrial node cell differentiation	8.770254e-4
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	8.770254e-4
GO:0003210	cardiac atrium formation	8.770254e-4
GO:0032738	positive regulation of interleukin-15 production	8.770254e-4
GO:0003236	sinus venosus morphogenesis	8.770254e-4
GO:0003241	growth involved in heart morphogenesis	8.770254e-4
GO:0003259	cardioblast anterior-lateral migration	8.770254e-4
GO:0044314	protein K27-linked ubiquitination	9.066143e-4
GO:0060741	prostate gland stromal morphogenesis	9.109349e-4
GO:0051898	negative regulation of protein kinase B signaling cascade	9.119123e-4
GO:0018364	peptidyl-glutamine methylation	9.389554e-4
GO:0006844	acyl carnitine transport	9.389554e-4
GO:0006756	AMP phosphorylation	9.389554e-4
GO:0031167	rRNA methylation	9.650346e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	9.873060e-4
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	9.912274e-4
GO:0060318	definitive erythrocyte differentiation	1.013457e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.020316e-3
GO:0060876	semicircular canal formation	1.091479e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	1.125763e-3
GO:0060458	right lung development	1.138040e-3
GO:0006927	transformed cell apoptosis	1.192731e-3
GO:0035305	negative regulation of dephosphorylation	1.208485e-3
GO:0010498	proteasomal protein catabolic process	1.222363e-3
GO:0070079	histone H4-R3 demethylation	1.265351e-3
GO:0070078	histone H3-R2 demethylation	1.265351e-3
GO:0015680	intracellular copper ion transport	1.265351e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.265351e-3
GO:0000959	mitochondrial RNA metabolic process	1.308116e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	1.318961e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	1.318961e-3
GO:0051984	positive regulation of chromosome segregation	1.318961e-3
GO:0033342	negative regulation of collagen binding	1.318961e-3
GO:0006311	meiotic gene conversion	1.318961e-3
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1.336267e-3
GO:2000016	negative regulation of determination of dorsal identity	1.375096e-3
GO:0034699	response to luteinizing hormone stimulus	1.375096e-3
GO:0045040	protein import into mitochondrial outer membrane	1.381614e-3
GO:0015074	DNA integration	1.424292e-3
GO:0072321	chaperone-mediated protein transport	1.455405e-3
GO:0034968	histone lysine methylation	1.468600e-3
GO:0006283	transcription-coupled nucleotide-excision repair	1.513970e-3
GO:0006924	activation-induced cell death of T cells	1.523726e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	1.528094e-3
GO:0048524	positive regulation of viral reproduction	1.529176e-3
GO:0046164	alcohol catabolic process	1.547846e-3
GO:0006449	regulation of translational termination	1.555171e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	1.560820e-3
GO:0060029	convergent extension involved in organogenesis	1.576684e-3
GO:0006406	mRNA export from nucleus	1.584318e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	1.585781e-3
GO:0021561	facial nerve development	1.585781e-3
GO:0021570	rhombomere 4 development	1.595880e-3
GO:0048102	autophagic cell death	1.636784e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.641889e-3
GO:0019047	provirus integration	1.662464e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	1.699202e-3
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	1.700538e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.755321e-3
GO:0006405	RNA export from nucleus	1.809327e-3
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	1.839698e-3
GO:0035646	endosome to melanosome transport	1.906966e-3
GO:0032581	ER-dependent peroxisome organization	1.906966e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1.972626e-3
GO:0003108	negative regulation of the force of heart contraction by chemical signal	1.987149e-3
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.000763e-3
GO:0051351	positive regulation of ligase activity	2.027100e-3
GO:0006390	transcription from mitochondrial promoter	2.027656e-3
GO:0030917	midbrain-hindbrain boundary development	2.032701e-3
GO:0071777	positive regulation of cell cycle cytokinesis	2.056295e-3
GO:0006108	malate metabolic process	2.085162e-3
GO:0046416	D-amino acid metabolic process	2.094444e-3
GO:0006173	dADP biosynthetic process	2.094444e-3
GO:0051083	'de novo' cotranslational protein folding	2.100690e-3
GO:0006548	histidine catabolic process	2.108883e-3
GO:0021599	abducens nerve formation	2.205514e-3
GO:0007634	optokinetic behavior	2.205514e-3
GO:0042136	neurotransmitter biosynthetic process	2.205869e-3
GO:0001522	pseudouridine synthesis	2.268564e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	2.302234e-3
GO:0032446	protein modification by small protein conjugation	2.325097e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	2.383867e-3
GO:0060623	regulation of chromosome condensation	2.383867e-3
GO:0071283	cellular response to iron(III) ion	2.383867e-3
GO:0046680	response to DDT	2.383867e-3
GO:2000009	negative regulation of protein localization at cell surface	2.383867e-3
GO:0046380	N-acetylneuraminate biosynthetic process	2.383867e-3
GO:0016078	tRNA catabolic process	2.383867e-3
GO:0001682	tRNA 5'-leader removal	2.383867e-3
GO:0043456	regulation of pentose-phosphate shunt	2.383867e-3
GO:0045819	positive regulation of glycogen catabolic process	2.454081e-3
GO:0015728	mevalonate transport	2.586136e-3
GO:0015986	ATP synthesis coupled proton transport	2.608729e-3
GO:0042373	vitamin K metabolic process	2.641856e-3
GO:0002115	store-operated calcium entry	2.641856e-3
GO:0034389	lipid particle organization	2.641856e-3
GO:0043632	modification-dependent macromolecule catabolic process	2.649564e-3
GO:0000236	mitotic prometaphase	2.737197e-3
GO:0006266	DNA ligation	2.785019e-3
GO:0006540	glutamate decarboxylation to succinate	2.788963e-3
GO:0006353	transcription termination, DNA-dependent	2.802650e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	2.816018e-3
GO:0048633	positive regulation of skeletal muscle tissue growth	2.862643e-3
GO:0042420	dopamine catabolic process	2.885138e-3
GO:0033578	protein glycosylation in Golgi	2.935042e-3
GO:0015827	tryptophan transport	2.935042e-3
GO:0042053	regulation of dopamine metabolic process	2.968341e-3
GO:0006361	transcription initiation from RNA polymerase I promoter	2.968824e-3
GO:0050686	negative regulation of mRNA processing	2.997684e-3
GO:0006730	one-carbon metabolic process	3.042484e-3
GO:0030967	ER-nuclear sterol response pathway	3.179577e-3
GO:0045922	negative regulation of fatty acid metabolic process	3.217646e-3
GO:0051103	DNA ligation involved in DNA repair	3.232165e-3
GO:0006259	DNA metabolic process	3.278000e-3
GO:0040015	negative regulation of multicellular organism growth	3.329900e-3
GO:0006376	mRNA splice site selection	3.336387e-3
GO:2000620	positive regulation of histone H4-K16 acetylation	3.443857e-3
GO:0070512	positive regulation of histone H4-K20 methylation	3.443857e-3
GO:2000617	positive regulation of histone H3-K9 acetylation	3.443857e-3
GO:0009088	threonine biosynthetic process	3.443857e-3
GO:0007057	spindle assembly involved in female meiosis I	3.443857e-3
GO:0070368	positive regulation of hepatocyte differentiation	3.443857e-3
GO:0006529	asparagine biosynthetic process	3.476233e-3
GO:0050975	sensory perception of touch	3.493257e-3
GO:0022007	convergent extension involved in neural plate elongation	3.512318e-3
GO:0021993	initiation of neural tube closure	3.559286e-3
GO:0009052	pentose-phosphate shunt, non-oxidative branch	3.637821e-3
GO:0016559	peroxisome fission	3.678485e-3
GO:0014028	notochord formation	3.678485e-3
GO:0021506	anterior neuropore closure	3.741342e-3
GO:0006659	phosphatidylserine biosynthetic process	3.746358e-3
GO:0002011	morphogenesis of an epithelial sheet	3.885642e-3
GO:0006547	histidine metabolic process	3.900350e-3
GO:0048370	lateral mesoderm formation	3.939995e-3
GO:0070647	protein modification by small protein conjugation or removal	3.983207e-3
GO:0031123	RNA 3'-end processing	4.004450e-3
GO:0042254	ribosome biogenesis	4.032206e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	4.100980e-3
GO:0018205	peptidyl-lysine modification	4.116836e-3
GO:0031848	protection from non-homologous end joining at telomere	4.135496e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4.185424e-3
GO:0033091	positive regulation of immature T cell proliferation	4.240812e-3
GO:0006538	glutamate catabolic process	4.257007e-3
GO:0006098	pentose-phosphate shunt	4.303467e-3
GO:0048561	establishment of organ orientation	4.398459e-3
GO:0060821	inactivation of X chromosome by DNA methylation	4.398459e-3
GO:0009107	lipoate biosynthetic process	4.398459e-3
GO:0014904	myotube cell development	4.398459e-3
GO:0001830	trophectodermal cell fate commitment	4.398459e-3
GO:0019321	pentose metabolic process	4.406065e-3
GO:0032288	myelin assembly	4.521504e-3
GO:0032467	positive regulation of cytokinesis	4.524956e-3
GO:0021546	rhombomere development	4.602047e-3
GO:0000279	M phase	4.654803e-3
GO:0031427	response to methotrexate	4.667959e-3
GO:0018352	protein-pyridoxal-5-phosphate linkage	4.667959e-3
GO:0006110	regulation of glycolysis	4.819222e-3
GO:0019941	modification-dependent protein catabolic process	4.835603e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	4.837361e-3
GO:0000244	assembly of spliceosomal tri-snRNP	4.914657e-3
GO:0032042	mitochondrial DNA metabolic process	4.968149e-3
GO:0042450	arginine biosynthetic process via ornithine	5.042058e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	5.042058e-3
GO:0045212	neurotransmitter receptor biosynthetic process	5.042058e-3
GO:0019358	nicotinate nucleotide salvage	5.042058e-3
GO:0006781	succinyl-CoA pathway	5.042058e-3
GO:0006713	glucocorticoid catabolic process	5.042058e-3
GO:0051081	nuclear envelope disassembly	5.405387e-3
GO:0044257	cellular protein catabolic process	5.539544e-3
GO:0046599	regulation of centriole replication	5.557134e-3
GO:0033182	regulation of histone ubiquitination	5.703197e-3
GO:0090007	regulation of mitotic anaphase	5.703197e-3
GO:0006051	N-acetylmannosamine metabolic process	5.703197e-3
GO:0050935	iridophore differentiation	5.708418e-3
GO:0048937	lateral line nerve glial cell development	5.708418e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	5.794472e-3
GO:0070979	protein K11-linked ubiquitination	5.845279e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	5.946158e-3
GO:0003326	pancreatic A cell fate commitment	5.946158e-3
GO:0003329	pancreatic PP cell fate commitment	5.946158e-3
GO:0042941	D-alanine transport	5.986508e-3
GO:0006975	DNA damage induced protein phosphorylation	5.991269e-3
GO:0001507	acetylcholine catabolic process in synaptic cleft	6.085517e-3
GO:0021997	neural plate axis specification	6.197813e-3
GO:0009262	deoxyribonucleotide metabolic process	6.243133e-3
GO:0006301	postreplication repair	6.319372e-3
GO:0048285	organelle fission	6.432751e-3
GO:0006511	ubiquitin-dependent protein catabolic process	6.476886e-3
GO:0045046	protein import into peroxisome membrane	6.545017e-3
GO:0006369	termination of RNA polymerase II transcription	6.580961e-3
GO:0001842	neural fold formation	6.613402e-3
GO:0002086	diaphragm contraction	6.613402e-3
GO:0030953	astral microtubule organization	6.629561e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	6.658419e-3
GO:0009648	photoperiodism	6.658419e-3
GO:0006260	DNA replication	6.830305e-3
GO:0003016	respiratory system process	6.870129e-3
GO:0010939	regulation of necrotic cell death	6.927837e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	7.128620e-3
GO:0070873	regulation of glycogen metabolic process	7.132369e-3
GO:0048280	vesicle fusion with Golgi apparatus	7.264310e-3
GO:0018022	peptidyl-lysine methylation	7.271147e-3
GO:0021548	pons development	7.320733e-3
GO:0048631	regulation of skeletal muscle tissue growth	7.482893e-3
GO:0021660	rhombomere 3 formation	7.526543e-3
GO:0021666	rhombomere 5 formation	7.526543e-3
GO:0015866	ADP transport	7.526543e-3
GO:0090084	negative regulation of inclusion body assembly	7.592156e-3
GO:0045351	type I interferon biosynthetic process	7.698349e-3
GO:0071455	cellular response to hyperoxia	7.731008e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	7.731008e-3
GO:0001840	neural plate development	7.822965e-3
GO:0007379	segment specification	7.825727e-3
GO:0051457	maintenance of protein location in nucleus	7.889435e-3
GO:0071874	cellular response to norepinephrine stimulus	8.211325e-3
GO:0009804	coumarin metabolic process	8.211325e-3
GO:0031914	negative regulation of synaptic plasticity	8.211325e-3
GO:0046984	regulation of hemoglobin biosynthetic process	8.212042e-3
GO:0071242	cellular response to ammonium ion	8.212042e-3
GO:0006233	dTDP biosynthetic process	8.212042e-3
GO:0051154	negative regulation of striated muscle cell differentiation	8.311320e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	8.468440e-3
GO:0045773	positive regulation of axon extension	8.482946e-3
GO:0015853	adenine transport	8.522203e-3
GO:0043570	maintenance of DNA repeat elements	8.556766e-3
GO:0042424	catecholamine catabolic process	8.572690e-3
GO:0045081	negative regulation of interleukin-10 biosynthetic process	8.812842e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	8.834795e-3
GO:0050883	musculoskeletal movement, spinal reflex action	9.145162e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	9.145162e-3
GO:0070370	cellular heat acclimation	9.145162e-3
GO:0048291	isotype switching to IgG isotypes	9.145162e-3
GO:0002368	B cell cytokine production	9.145162e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	9.145162e-3
GO:0006430	lysyl-tRNA aminoacylation	9.145162e-3
GO:0009436	glyoxylate catabolic process	9.145162e-3
GO:0009225	nucleotide-sugar metabolic process	9.164810e-3
GO:0002331	pre-B cell allelic exclusion	9.654156e-3
GO:0032929	negative regulation of superoxide anion generation	9.654156e-3
GO:0060052	neurofilament cytoskeleton organization	9.696071e-3
GO:0060872	semicircular canal development	9.765264e-3
GO:0008334	histone mRNA metabolic process	1.032906e-2
GO:0043931	ossification involved in bone maturation	1.036948e-2
GO:0051935	glutamate uptake involved in synaptic transmission	1.036948e-2
GO:0070366	regulation of hepatocyte differentiation	1.048405e-2
GO:0010070	zygote asymmetric cell division	1.048405e-2
GO:0021586	pons maturation	1.048610e-2
GO:0016574	histone ubiquitination	1.055038e-2
GO:0010225	response to UV-C	1.063722e-2
GO:0009263	deoxyribonucleotide biosynthetic process	1.063722e-2
GO:0050689	negative regulation of defense response to virus by host	1.083641e-2
GO:0006313	transposition, DNA-mediated	1.083641e-2
GO:0048075	positive regulation of eye pigmentation	1.083641e-2
GO:0051256	spindle midzone assembly involved in mitosis	1.085382e-2
GO:0035308	negative regulation of protein dephosphorylation	1.093544e-2
GO:0045454	cell redox homeostasis	1.112535e-2
GO:0060606	tube closure	1.117525e-2
GO:0005981	regulation of glycogen catabolic process	1.118242e-2
GO:0001738	morphogenesis of a polarized epithelium	1.131982e-2
GO:0043543	protein acylation	1.153459e-2
GO:0048714	positive regulation of oligodendrocyte differentiation	1.164463e-2
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.206743e-2
GO:0045988	negative regulation of striated muscle contraction	1.208821e-2
GO:0010940	positive regulation of necrotic cell death	1.234359e-2
GO:0022411	cellular component disassembly	1.240684e-2
GO:0048752	semicircular canal morphogenesis	1.241379e-2
GO:0000729	DNA double-strand break processing	1.261926e-2
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.267017e-2
GO:0019088	immortalization of host cell by virus	1.297810e-2
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	1.297810e-2
GO:0006741	NADP biosynthetic process	1.297810e-2
GO:0006231	dTMP biosynthetic process	1.297810e-2
GO:0071843	cellular component biogenesis at cellular level	1.300540e-2
GO:0006367	transcription initiation from RNA polymerase II promoter	1.308092e-2
GO:0090085	regulation of protein deubiquitination	1.308678e-2
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	1.308678e-2
GO:0032025	response to cobalt ion	1.372709e-2
GO:0032148	activation of protein kinase B activity	1.389966e-2
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.391810e-2
GO:0043105	negative regulation of GTP cyclohydrolase I activity	1.391810e-2
GO:0071506	cellular response to mycophenolic acid	1.393304e-2
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.393304e-2
GO:0006473	protein acetylation	1.395727e-2
GO:0009185	ribonucleoside diphosphate metabolic process	1.418058e-2
GO:0070537	histone H2A K63-linked deubiquitination	1.418425e-2
GO:0030719	P granule organization	1.418425e-2
GO:0030488	tRNA methylation	1.418425e-2
GO:0010591	regulation of lamellipodium assembly	1.429526e-2
GO:0016180	snRNA processing	1.438550e-2
GO:0007052	mitotic spindle organization	1.445637e-2
GO:0007007	inner mitochondrial membrane organization	1.449555e-2
GO:0071845	cellular component disassembly at cellular level	1.452574e-2
GO:0030163	protein catabolic process	1.455588e-2
GO:0006740	NADPH regeneration	1.464722e-2
GO:0009057	macromolecule catabolic process	1.472875e-2
GO:2000627	positive regulation of miRNA catabolic process	1.473124e-2
GO:0072661	protein targeting to plasma membrane	1.473124e-2
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	1.473124e-2
GO:0000964	mitochondrial RNA 5'-end processing	1.473124e-2
GO:0045039	protein import into mitochondrial inner membrane	1.479135e-2
GO:0007549	dosage compensation	1.479135e-2
GO:0033160	positive regulation of protein import into nucleus, translocation	1.482073e-2
GO:0097037	heme export	1.493572e-2
GO:0016095	polyprenol catabolic process	1.493572e-2
GO:0070407	oxidation-dependent protein catabolic process	1.493572e-2
GO:0060209	estrus	1.493572e-2
GO:0046168	glycerol-3-phosphate catabolic process	1.493572e-2
GO:0045910	negative regulation of DNA recombination	1.496396e-2
GO:0006479	protein methylation	1.519334e-2
GO:0071072	negative regulation of phospholipid biosynthetic process	1.531415e-2
GO:0006925	inflammatory cell apoptosis	1.531415e-2
GO:0001843	neural tube closure	1.537264e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.571060e-2
GO:0006268	DNA unwinding involved in replication	1.596080e-2
GO:0006014	D-ribose metabolic process	1.599651e-2
GO:0044154	histone H3-K14 acetylation	1.620575e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0000279	M phase	5.175640e-18
GO:0022403	cell cycle phase	6.006320e-14
GO:0006396	RNA processing	1.651736e-12
GO:0034660	ncRNA metabolic process	2.340635e-12
GO:0007067	mitosis	2.411433e-11
GO:0000087	M phase of mitotic cell cycle	3.169572e-11
GO:0007049	cell cycle	3.804385e-11
GO:0048285	organelle fission	6.107657e-11
GO:0034470	ncRNA processing	1.581911e-10
GO:0044260	cellular macromolecule metabolic process	2.737571e-10
GO:0032446	protein modification by small protein conjugation	3.243280e-10
GO:0006474	N-terminal protein amino acid acetylation	3.380637e-10
GO:0022402	cell cycle process	4.405413e-10
GO:0045116	protein neddylation	4.577588e-10
GO:0006406	mRNA export from nucleus	6.202904e-10
GO:0071843	cellular component biogenesis at cellular level	7.181907e-10
GO:0006405	RNA export from nucleus	7.911352e-10
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	9.279311e-10
GO:0022613	ribonucleoprotein complex biogenesis	1.035716e-9
GO:0090304	nucleic acid metabolic process	2.355902e-9
GO:0016567	protein ubiquitination	7.708246e-9
GO:0032515	negative regulation of phosphoprotein phosphatase activity	8.074746e-9
GO:0051004	regulation of lipoprotein lipase activity	1.074482e-8
GO:0031365	N-terminal protein amino acid modification	1.363996e-8
GO:0010896	regulation of triglyceride catabolic process	1.516177e-8
GO:0051301	cell division	1.903222e-8
GO:0006281	DNA repair	2.622703e-8
GO:0048368	lateral mesoderm development	2.990508e-8
GO:0006139	nucleobase-containing compound metabolic process	3.099602e-8
GO:0032467	positive regulation of cytokinesis	4.015033e-8
GO:0051168	nuclear export	5.462811e-8
GO:0000278	mitotic cell cycle	5.467557e-8
GO:0008380	RNA splicing	5.559596e-8
GO:0006364	rRNA processing	1.005487e-7
GO:0071168	protein localization to chromatin	1.010637e-7
GO:0007051	spindle organization	1.019481e-7
GO:0000395	nuclear mRNA 5'-splice site recognition	1.293804e-7
GO:0070647	protein modification by small protein conjugation or removal	1.806422e-7
GO:0042273	ribosomal large subunit biogenesis	1.875765e-7
GO:0030163	protein catabolic process	2.740612e-7
GO:0071169	establishment of protein localization to chromatin	3.239267e-7
GO:0010467	gene expression	4.206002e-7
GO:0043666	regulation of phosphoprotein phosphatase activity	4.533279e-7
GO:0051225	spindle assembly	6.190984e-7
GO:0043632	modification-dependent macromolecule catabolic process	6.734173e-7
GO:0006511	ubiquitin-dependent protein catabolic process	7.132775e-7
GO:0051276	chromosome organization	7.247728e-7
GO:0016072	rRNA metabolic process	8.440328e-7
GO:0019941	modification-dependent protein catabolic process	9.579181e-7
GO:0034587	piRNA metabolic process	1.413053e-6
GO:0071173	spindle assembly checkpoint	1.580068e-6
GO:0071777	positive regulation of cell cycle cytokinesis	1.869308e-6
GO:0034641	cellular nitrogen compound metabolic process	2.174772e-6
GO:0017196	N-terminal peptidyl-methionine acetylation	2.323278e-6
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.323278e-6
GO:0031577	spindle checkpoint	2.324707e-6
GO:0006105	succinate metabolic process	2.352568e-6
GO:0006207	'de novo' pyrimidine base biosynthetic process	2.598566e-6
GO:0031848	protection from non-homologous end joining at telomere	2.853847e-6
GO:0071826	ribonucleoprotein complex subunit organization	2.974232e-6
GO:0006974	response to DNA damage stimulus	2.996447e-6
GO:0010891	negative regulation of sequestering of triglyceride	3.208324e-6
GO:0034502	protein localization to chromosome	3.319145e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.409292e-6
GO:0060458	right lung development	3.511389e-6
GO:0006259	DNA metabolic process	3.674694e-6
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.802286e-6
GO:0006540	glutamate decarboxylation to succinate	3.802286e-6
GO:0022618	ribonucleoprotein complex assembly	4.084458e-6
GO:0051028	mRNA transport	4.922810e-6
GO:0042254	ribosome biogenesis	5.820473e-6
GO:0051321	meiotic cell cycle	5.830302e-6
GO:0090231	regulation of spindle checkpoint	6.308146e-6
GO:0034391	regulation of smooth muscle cell apoptosis	6.972187e-6
GO:0030263	apoptotic chromosome condensation	7.126478e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	8.040503e-6
GO:0030719	P granule organization	8.730732e-6
GO:0035520	monoubiquitinated protein deubiquitination	9.468788e-6
GO:0018206	peptidyl-methionine modification	9.468788e-6
GO:0009057	macromolecule catabolic process	9.826302e-6
GO:0051603	proteolysis involved in cellular protein catabolic process	1.202651e-5
GO:0006412	translation	1.317512e-5
GO:0030262	apoptotic nuclear change	1.369190e-5
GO:0006921	cellular component disassembly involved in apoptosis	1.376685e-5
GO:0006397	mRNA processing	1.577574e-5
GO:0010501	RNA secondary structure unwinding	1.785930e-5
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.852388e-5
GO:0007126	meiosis	2.070931e-5
GO:0016071	mRNA metabolic process	2.106599e-5
GO:0006538	glutamate catabolic process	2.293263e-5
GO:0006430	lysyl-tRNA aminoacylation	2.316030e-5
GO:0046452	dihydrofolate metabolic process	2.316030e-5
GO:0048239	negative regulation of DNA recombination at telomere	2.316030e-5
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	2.316030e-5
GO:0046853	inositol or phosphatidylinositol phosphorylation	2.364594e-5
GO:0019509	L-methionine salvage from methylthioadenosine	2.364594e-5
GO:0010312	detoxification of zinc ion	2.364594e-5
GO:0034442	regulation of lipoprotein oxidation	2.378171e-5
GO:0000245	spliceosome assembly	2.449180e-5
GO:0009262	deoxyribonucleotide metabolic process	2.662193e-5
GO:0044257	cellular protein catabolic process	2.691376e-5
GO:0050823	peptide antigen stabilization	2.834330e-5
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.834330e-5
GO:0050658	RNA transport	2.866830e-5
GO:0033523	histone H2B ubiquitination	2.980351e-5
GO:0034393	positive regulation of smooth muscle cell apoptosis	3.039079e-5
GO:0032516	positive regulation of phosphoprotein phosphatase activity	3.039079e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	3.423706e-5
GO:0010897	negative regulation of triglyceride catabolic process	3.423706e-5
GO:0006325	chromatin organization	3.457487e-5
GO:0016070	RNA metabolic process	3.604845e-5
GO:0035092	sperm chromatin condensation	3.782699e-5
GO:0007028	cytoplasm organization	3.881932e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	3.909920e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	4.325789e-5
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.425395e-5
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	4.494776e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	4.494776e-5
GO:0006403	RNA localization	4.948487e-5
GO:0032922	circadian regulation of gene expression	4.988908e-5
GO:0010898	positive regulation of triglyceride catabolic process	5.315921e-5
GO:0006391	transcription initiation from mitochondrial promoter	5.923590e-5
GO:0006807	nitrogen compound metabolic process	6.166126e-5
GO:0001880	Mullerian duct regression	6.245231e-5
GO:0006473	protein acetylation	6.417165e-5
GO:0006306	DNA methylation	6.644911e-5
GO:0010878	cholesterol storage	6.914715e-5
GO:0016568	chromatin modification	7.088201e-5
GO:0030300	regulation of intestinal cholesterol absorption	7.508108e-5
GO:0006669	sphinganine-1-phosphate biosynthetic process	8.042674e-5
GO:0032465	regulation of cytokinesis	8.610140e-5
GO:0044265	cellular macromolecule catabolic process	9.132566e-5
GO:0010889	regulation of sequestering of triglyceride	9.840043e-5
GO:0000460	maturation of 5.8S rRNA	9.981913e-5
GO:0090224	regulation of spindle organization	1.031739e-4
GO:0008608	attachment of spindle microtubules to kinetochore	1.032072e-4
GO:0046784	intronless viral mRNA export from host nucleus	1.091764e-4
GO:0010661	positive regulation of muscle cell apoptosis	1.091764e-4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.123564e-4
GO:0007059	chromosome segregation	1.182126e-4
GO:0042699	follicle-stimulating hormone signaling pathway	1.191050e-4
GO:0051103	DNA ligation involved in DNA repair	1.243078e-4
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	1.252663e-4
GO:2000682	positive regulation of rubidium ion transport	1.252663e-4
GO:0046604	positive regulation of mitotic centrosome separation	1.252663e-4
GO:0035826	rubidium ion transport	1.252663e-4
GO:0032784	regulation of transcription elongation, DNA-dependent	1.371415e-4
GO:0051006	positive regulation of lipoprotein lipase activity	1.375965e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	1.404827e-4
GO:0061084	negative regulation of protein refolding	1.411194e-4
GO:2000016	negative regulation of determination of dorsal identity	1.489109e-4
GO:0046607	positive regulation of centrosome cycle	1.489109e-4
GO:0043148	mitotic spindle stabilization	1.489109e-4
GO:0006713	glucocorticoid catabolic process	1.489109e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.489109e-4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.622464e-4
GO:0042851	L-alanine metabolic process	1.671031e-4
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	1.671031e-4
GO:0015876	acetyl-CoA transport	1.671031e-4
GO:0033169	histone H3-K9 demethylation	1.700914e-4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.713607e-4
GO:0007052	mitotic spindle organization	1.725940e-4
GO:0006982	response to lipid hydroperoxide	1.754155e-4
GO:0071174	mitotic cell cycle spindle checkpoint	1.754155e-4
GO:0043543	protein acylation	1.873365e-4
GO:0010872	regulation of cholesterol esterification	1.928377e-4
GO:0071476	cellular hypotonic response	1.963917e-4
GO:0006663	platelet activating factor biosynthetic process	1.963917e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	2.037840e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	2.133568e-4
GO:0072300	positive regulation of metanephric glomerulus development	2.156643e-4
GO:0051973	positive regulation of telomerase activity	2.162898e-4
GO:0071267	L-methionine salvage	2.162898e-4
GO:0035093	spermatogenesis, exchange of chromosomal proteins	2.162898e-4
GO:0051135	positive regulation of NK T cell activation	2.215679e-4
GO:0006545	glycine biosynthetic process	2.225002e-4
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.243098e-4
GO:0042559	pteridine-containing compound biosynthetic process	2.334035e-4
GO:0007256	activation of JNKK activity	2.360516e-4
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	2.394950e-4
GO:0000080	G1 phase of mitotic cell cycle	2.518346e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	2.653789e-4
GO:0065005	protein-lipid complex assembly	2.686174e-4
GO:0006370	mRNA capping	2.687521e-4
GO:0000375	RNA splicing, via transesterification reactions	2.901843e-4
GO:0051568	histone H3-K4 methylation	3.012027e-4
GO:0061088	regulation of sequestering of zinc ion	3.223409e-4
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	3.449717e-4
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	3.449717e-4
GO:0080125	multicellular structure septum development	3.449717e-4
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	3.449717e-4
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	3.449717e-4
GO:0046534	positive regulation of photoreceptor cell differentiation	3.449717e-4
GO:0007502	digestive tract mesoderm development	3.449717e-4
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	3.449717e-4
GO:0014858	positive regulation of skeletal muscle cell proliferation	3.449717e-4
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	3.449717e-4
GO:0008033	tRNA processing	3.468138e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	3.597063e-4
GO:0000959	mitochondrial RNA metabolic process	3.647395e-4
GO:0048050	post-embryonic eye morphogenesis	3.729828e-4
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	3.735858e-4
GO:0010873	positive regulation of cholesterol esterification	3.857848e-4
GO:0046605	regulation of centrosome cycle	3.905052e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	3.953565e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	3.953565e-4
GO:0032383	regulation of intracellular cholesterol transport	3.953565e-4
GO:0015966	diadenosine tetraphosphate biosynthetic process	3.953565e-4
GO:0048808	male genitalia morphogenesis	4.056197e-4
GO:0046112	nucleobase biosynthetic process	4.645585e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	4.757753e-4
GO:0045351	type I interferon biosynthetic process	4.829030e-4
GO:0000209	protein polyubiquitination	4.920773e-4
GO:0050748	negative regulation of lipoprotein metabolic process	4.991296e-4
GO:0048352	paraxial mesoderm structural organization	5.199102e-4
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.199102e-4
GO:0008208	C21-steroid hormone catabolic process	5.199102e-4
GO:0021998	neural plate mediolateral regionalization	5.199102e-4
GO:0009299	mRNA transcription	5.280570e-4
GO:0006668	sphinganine-1-phosphate metabolic process	5.280570e-4
GO:0043170	macromolecule metabolic process	5.288999e-4
GO:0000002	mitochondrial genome maintenance	5.646297e-4
GO:0072528	pyrimidine-containing compound biosynthetic process	5.779476e-4
GO:0090207	regulation of triglyceride metabolic process	5.849224e-4
GO:0045056	transcytosis	5.973964e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	6.014806e-4
GO:0030202	heparin metabolic process	6.014806e-4
GO:0006260	DNA replication	6.113872e-4
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	6.192028e-4
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	6.192028e-4
GO:0032859	activation of Ral GTPase activity	6.214775e-4
GO:0010921	regulation of phosphatase activity	6.616276e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	6.654925e-4
GO:0006399	tRNA metabolic process	6.783509e-4
GO:0045948	positive regulation of translational initiation	7.085465e-4
GO:0030201	heparan sulfate proteoglycan metabolic process	7.085465e-4
GO:0016068	type I hypersensitivity	7.435968e-4
GO:0008334	histone mRNA metabolic process	8.008228e-4
GO:0070936	protein K48-linked ubiquitination	8.341373e-4
GO:0044058	regulation of digestive system process	8.702805e-4
GO:0045585	positive regulation of cytotoxic T cell differentiation	8.753311e-4
GO:0048291	isotype switching to IgG isotypes	8.864456e-4
GO:0002368	B cell cytokine production	8.864456e-4
GO:0000226	microtubule cytoskeleton organization	9.191301e-4
GO:0035566	regulation of metanephros size	9.261041e-4
GO:0009064	glutamine family amino acid metabolic process	9.360406e-4
GO:0031119	tRNA pseudouridine synthesis	9.510322e-4
GO:0010725	regulation of primitive erythrocyte differentiation	9.510322e-4
GO:0044237	cellular metabolic process	9.716786e-4
GO:0060621	negative regulation of cholesterol import	9.909382e-4
GO:0009086	methionine biosynthetic process	1.036730e-3
GO:2000015	regulation of determination of dorsal identity	1.037982e-3
GO:0010888	negative regulation of lipid storage	1.042592e-3
GO:0070328	triglyceride homeostasis	1.061465e-3
GO:0055090	acylglycerol homeostasis	1.066690e-3
GO:0060236	regulation of mitotic spindle organization	1.113110e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.113110e-3
GO:0016539	intein-mediated protein splicing	1.113110e-3
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.113110e-3
GO:0072172	mesonephric tubule formation	1.175454e-3
GO:0050713	negative regulation of interleukin-1 beta secretion	1.237879e-3
GO:0072075	metanephric mesenchyme development	1.240269e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	1.262963e-3
GO:0043414	macromolecule methylation	1.277222e-3
GO:0018243	protein O-linked glycosylation via threonine	1.288280e-3
GO:0032799	low-density lipoprotein receptor particle metabolic process	1.288280e-3
GO:0018242	protein O-linked glycosylation via serine	1.288280e-3
GO:0051972	regulation of telomerase activity	1.296734e-3
GO:0034968	histone lysine methylation	1.300716e-3
GO:0051095	regulation of helicase activity	1.302633e-3
GO:0070076	histone lysine demethylation	1.313403e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	1.338283e-3
GO:0070198	protein localization to chromosome, telomeric region	1.339437e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	1.410963e-3
GO:0006555	methionine metabolic process	1.411791e-3
GO:0006493	protein O-linked glycosylation	1.417669e-3
GO:0043691	reverse cholesterol transport	1.443286e-3
GO:0048255	mRNA stabilization	1.474413e-3
GO:0006284	base-excision repair	1.478379e-3
GO:0043484	regulation of RNA splicing	1.504826e-3
GO:0043046	DNA methylation involved in gamete generation	1.525028e-3
GO:0090193	positive regulation of glomerulus development	1.534253e-3
GO:0045292	nuclear mRNA cis splicing, via spliceosome	1.534253e-3
GO:0009067	aspartate family amino acid biosynthetic process	1.583781e-3
GO:0042984	regulation of amyloid precursor protein biosynthetic process	1.635649e-3
GO:0070370	cellular heat acclimation	1.655504e-3
GO:0071279	cellular response to cobalt ion	1.655504e-3
GO:0010637	negative regulation of mitochondrial fusion	1.655504e-3
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.655504e-3
GO:0035356	cellular triglyceride homeostasis	1.655504e-3
GO:0051096	positive regulation of helicase activity	1.709674e-3
GO:0043687	post-translational protein modification	1.876866e-3
GO:0006266	DNA ligation	1.876866e-3
GO:0032025	response to cobalt ion	1.883446e-3
GO:0002227	innate immune response in mucosa	1.883446e-3
GO:0050434	positive regulation of viral transcription	1.925958e-3
GO:0015724	formate transport	1.930944e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	2.002624e-3
GO:0006390	transcription from mitochondrial promoter	2.036067e-3
GO:0009200	deoxyribonucleoside triphosphate metabolic process	2.123221e-3
GO:0035269	protein O-linked mannosylation	2.134517e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.159962e-3
GO:0031167	rRNA methylation	2.159962e-3
GO:0006308	DNA catabolic process	2.226217e-3
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	2.235625e-3
GO:0045837	negative regulation of membrane potential	2.237177e-3
GO:0060447	bud outgrowth involved in lung branching	2.238611e-3
GO:0032119	sequestering of zinc ion	2.243109e-3
GO:0060620	regulation of cholesterol import	2.305330e-3
GO:0090083	regulation of inclusion body assembly	2.305330e-3
GO:0010887	negative regulation of cholesterol storage	2.305330e-3
GO:0008629	induction of apoptosis by intracellular signals	2.378316e-3
GO:0006376	mRNA splice site selection	2.379133e-3
GO:0042667	auditory receptor cell fate specification	2.408804e-3
GO:0045609	positive regulation of auditory receptor cell differentiation	2.408804e-3
GO:0019556	histidine catabolic process to glutamate and formamide	2.408804e-3
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	2.408804e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	2.410055e-3
GO:0070534	protein K63-linked ubiquitination	2.428906e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	2.449198e-3
GO:0006264	mitochondrial DNA replication	2.513753e-3
GO:0071845	cellular component disassembly at cellular level	2.538856e-3
GO:0046501	protoporphyrinogen IX metabolic process	2.631456e-3
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	2.631456e-3
GO:0043305	negative regulation of mast cell degranulation	2.631456e-3
GO:0003140	determination of left/right asymmetry in lateral mesoderm	2.631456e-3
GO:0060463	lung lobe morphogenesis	2.673220e-3
GO:0032606	type I interferon production	2.677036e-3
GO:0051318	G1 phase	2.725303e-3
GO:0071044	histone mRNA catabolic process	2.789107e-3
GO:0090307	spindle assembly involved in mitosis	2.849342e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.869296e-3
GO:0019348	dolichol metabolic process	2.869296e-3
GO:0014904	myotube cell development	2.920735e-3
GO:0044267	cellular protein metabolic process	2.949269e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	2.981742e-3
GO:0000710	meiotic mismatch repair	3.079370e-3
GO:0009452	RNA capping	3.079370e-3
GO:0031508	centromeric heterochromatin formation	3.138641e-3
GO:0034645	cellular macromolecule biosynthetic process	3.341354e-3
GO:0042089	cytokine biosynthetic process	3.358514e-3
GO:0022411	cellular component disassembly	3.402279e-3
GO:0072184	renal vesicle progenitor cell differentiation	3.486172e-3
GO:0072169	specification of posterior mesonephric tubule identity	3.486172e-3
GO:0072208	metanephric smooth muscle tissue development	3.486172e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	3.486172e-3
GO:0072168	specification of anterior mesonephric tubule identity	3.486172e-3
GO:0090131	mesenchyme migration	3.486172e-3
GO:0072259	metanephric interstitial cell development	3.486172e-3
GO:0070368	positive regulation of hepatocyte differentiation	3.486172e-3
GO:0048371	lateral mesodermal cell differentiation	3.486172e-3
GO:0035674	tricarboxylic acid transmembrane transport	3.486172e-3
GO:0048613	embryonic ectodermal digestive tract morphogenesis	3.486172e-3
GO:0060446	branching involved in open tracheal system development	3.486172e-3
GO:0060461	right lung morphogenesis	3.486172e-3
GO:0014822	detection of wounding	3.486172e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	3.525126e-3
GO:0055026	negative regulation of cardiac muscle tissue development	3.525126e-3
GO:0051151	negative regulation of smooth muscle cell differentiation	3.587303e-3
GO:0006283	transcription-coupled nucleotide-excision repair	3.587303e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	3.594408e-3
GO:0016574	histone ubiquitination	3.643530e-3
GO:0090208	positive regulation of triglyceride metabolic process	3.690119e-3
GO:0071470	cellular response to osmotic stress	3.744353e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.789755e-3
GO:0048859	formation of anatomical boundary	3.789755e-3
GO:0044205	'de novo' UMP biosynthetic process	3.789755e-3
GO:0016570	histone modification	3.937589e-3
GO:0042136	neurotransmitter biosynthetic process	4.037415e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	4.037415e-3
GO:0015931	nucleobase-containing compound transport	4.054763e-3
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	4.436462e-3
GO:0006513	protein monoubiquitination	4.462426e-3
GO:0007089	traversing start control point of mitotic cell cycle	4.466701e-3
GO:0060459	left lung development	4.470393e-3
GO:0040016	embryonic cleavage	4.470393e-3
GO:0006298	mismatch repair	4.703847e-3
GO:0016926	protein desumoylation	4.759902e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	4.807219e-3
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	4.807219e-3
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	4.874351e-3
GO:0030210	heparin biosynthetic process	4.874351e-3
GO:0021936	regulation of cerebellar granule cell precursor proliferation	4.910127e-3
GO:0000097	sulfur amino acid biosynthetic process	4.910127e-3
GO:0018076	N-terminal peptidyl-lysine acetylation	4.926007e-3
GO:0072162	metanephric mesenchymal cell differentiation	5.021908e-3
GO:0033091	positive regulation of immature T cell proliferation	5.021908e-3
GO:0015969	guanosine tetraphosphate metabolic process	5.093401e-3
GO:0006666	3-keto-sphinganine metabolic process	5.093401e-3
GO:0051567	histone H3-K9 methylation	5.099396e-3
GO:0034421	post-translational protein acetylation	5.291656e-3
GO:0008063	Toll signaling pathway	5.291656e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	5.517563e-3
GO:0043457	regulation of cellular respiration	5.517563e-3
GO:0019438	aromatic compound biosynthetic process	5.622166e-3
GO:0050711	negative regulation of interleukin-1 secretion	5.691212e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	5.771652e-3
GO:0048680	positive regulation of axon regeneration	5.851859e-3
GO:2000009	negative regulation of protein localization at cell surface	6.034564e-3
GO:0080164	regulation of nitric oxide metabolic process	6.034564e-3
GO:0040038	polar body extrusion after meiotic divisions	6.034564e-3
GO:0009443	pyridoxal 5'-phosphate salvage	6.034564e-3
GO:0042941	D-alanine transport	6.034564e-3
GO:0032864	activation of Cdc42 GTPase activity	6.075735e-3
GO:0000154	rRNA modification	6.075735e-3
GO:0035305	negative regulation of dephosphorylation	6.174879e-3
GO:0051340	regulation of ligase activity	6.289372e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	6.309559e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	6.398437e-3
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	6.435025e-3
GO:0051322	anaphase	6.460621e-3
GO:0032933	SREBP-mediated signaling pathway	6.557827e-3
GO:0018394	peptidyl-lysine acetylation	6.711400e-3
GO:0035630	bone mineralization involved in bone maturation	6.748683e-3
GO:0051205	protein insertion into membrane	6.806825e-3
GO:0070508	cholesterol import	6.807240e-3
GO:0035308	negative regulation of protein dephosphorylation	6.807240e-3
GO:0043094	cellular metabolic compound salvage	6.807240e-3
GO:0009396	folic acid-containing compound biosynthetic process	6.823744e-3
GO:0033084	regulation of immature T cell proliferation in thymus	6.852513e-3
GO:0009263	deoxyribonucleotide biosynthetic process	7.180157e-3
GO:0046532	regulation of photoreceptor cell differentiation	7.199693e-3
GO:0010871	negative regulation of receptor biosynthetic process	7.199693e-3
GO:0006290	pyrimidine dimer repair	7.296986e-3
GO:0006304	DNA modification	7.418726e-3
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	7.628063e-3
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	7.628063e-3
GO:0021570	rhombomere 4 development	7.628063e-3
GO:0016569	covalent chromatin modification	7.663713e-3
GO:0018393	internal peptidyl-lysine acetylation	7.684176e-3
GO:0031442	positive regulation of mRNA 3'-end processing	7.793371e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	7.920663e-3
GO:0032780	negative regulation of ATPase activity	7.973107e-3
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	7.973107e-3
GO:0006352	transcription initiation, DNA-dependent	7.988940e-3
GO:0051983	regulation of chromosome segregation	8.033773e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	8.333218e-3
GO:0048382	mesendoderm development	8.333946e-3
GO:0030970	retrograde protein transport, ER to cytosol	8.333946e-3
GO:0002352	B cell negative selection	8.333946e-3
GO:0009059	macromolecule biosynthetic process	8.486200e-3
GO:0050685	positive regulation of mRNA processing	8.769294e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	8.912412e-3
GO:0048633	positive regulation of skeletal muscle tissue growth	8.938344e-3
GO:0046602	regulation of mitotic centrosome separation	8.938344e-3
GO:0050689	negative regulation of defense response to virus by host	8.938344e-3
GO:0019307	mannose biosynthetic process	8.938344e-3
GO:0000722	telomere maintenance via recombination	8.938344e-3
GO:0048793	pronephros development	9.060077e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	9.153390e-3
GO:2000256	positive regulation of male germ cell proliferation	9.235770e-3
GO:0042840	D-glucuronate catabolic process	9.235770e-3
GO:0042231	interleukin-13 biosynthetic process	9.235770e-3
GO:0035470	positive regulation of vascular wound healing	9.235770e-3
GO:0009066	aspartate family amino acid metabolic process	9.410593e-3
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	9.507812e-3
GO:0070997	neuron death	9.669009e-3
GO:0000910	cytokinesis	9.701324e-3
GO:0050746	regulation of lipoprotein metabolic process	9.736636e-3
GO:0048015	phosphatidylinositol-mediated signaling	9.803291e-3
GO:0001831	trophectodermal cellular morphogenesis	9.845930e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	9.950122e-3
GO:0048280	vesicle fusion with Golgi apparatus	9.950122e-3
GO:0048733	sebaceous gland development	9.950122e-3
GO:0010833	telomere maintenance via telomere lengthening	9.950122e-3
GO:0007529	establishment of synaptic specificity at neuromuscular junction	9.950122e-3
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	9.950122e-3
GO:0043088	regulation of Cdc42 GTPase activity	1.001828e-2
GO:0051438	regulation of ubiquitin-protein ligase activity	1.020066e-2
GO:0007080	mitotic metaphase plate congression	1.053300e-2
GO:0051313	attachment of spindle microtubules to chromosome	1.060734e-2
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	1.062454e-2
GO:0061360	optic chiasma development	1.062454e-2
GO:2000597	positive regulation of optic nerve formation	1.062454e-2
GO:0035799	ureter maturation	1.062454e-2
GO:0006788	heme oxidation	1.062454e-2
GO:0006481	C-terminal protein methylation	1.062454e-2
GO:0035562	negative regulation of chromatin binding	1.062454e-2
GO:0021633	optic nerve structural organization	1.062454e-2
GO:0021650	vestibulocochlear nerve formation	1.062454e-2
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	1.065238e-2
GO:0042256	mature ribosome assembly	1.065238e-2
GO:0006172	ADP biosynthetic process	1.065238e-2
GO:0007228	positive regulation of hh target transcription factor activity	1.065238e-2
GO:0031047	gene silencing by RNA	1.070569e-2
GO:0030901	midbrain development	1.079039e-2
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	1.099511e-2
GO:0010724	regulation of definitive erythrocyte differentiation	1.105479e-2
GO:0051238	sequestering of metal ion	1.105479e-2
GO:0006446	regulation of translational initiation	1.156078e-2
GO:0033083	regulation of immature T cell proliferation	1.179829e-2
GO:0061099	negative regulation of protein tyrosine kinase activity	1.198845e-2
GO:0030833	regulation of actin filament polymerization	1.201326e-2
GO:0043486	histone exchange	1.213949e-2
GO:0007034	vacuolar transport	1.216239e-2
GO:0032916	positive regulation of transforming growth factor beta3 production	1.227440e-2
GO:0034619	cellular chaperone-mediated protein complex assembly	1.227440e-2
GO:0050684	regulation of mRNA processing	1.240479e-2
GO:0010823	negative regulation of mitochondrion organization	1.244305e-2
GO:0006888	ER to Golgi vesicle-mediated transport	1.255232e-2