Novel motif:147

name:	motif147_ATATCCAGTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0033693	neurofilament bundle assembly	3.315113e-26
GO:0045110	intermediate filament bundle assembly	6.332649e-20
GO:0008090	retrograde axon cargo transport	1.757526e-18
GO:0008089	anterograde axon cargo transport	3.167902e-18
GO:0019896	axon transport of mitochondrion	7.677828e-18
GO:0010970	microtubule-based transport	5.286912e-15
GO:0051915	induction of synaptic plasticity by chemical substance	7.356728e-15
GO:0031116	positive regulation of microtubule polymerization	6.029158e-14
GO:0007320	insemination	1.363098e-13
GO:0048676	axon extension involved in development	1.942497e-13
GO:0006928	cellular component movement	3.282433e-13
GO:0007620	copulation	7.057838e-13
GO:0030705	cytoskeleton-dependent intracellular transport	7.361316e-13
GO:0060052	neurofilament cytoskeleton organization	1.278851e-12
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1.117891e-11
GO:0014012	peripheral nervous system axon regeneration	1.330060e-11
GO:0030261	chromosome condensation	2.796898e-11
GO:0007155	cell adhesion	4.380789e-11
GO:0007018	microtubule-based movement	1.715339e-10
GO:0006950	response to stress	3.015746e-10
GO:0045104	intermediate filament cytoskeleton organization	5.605448e-10
GO:0008088	axon cargo transport	7.943483e-10
GO:0045103	intermediate filament-based process	2.055615e-9
GO:0048769	sarcomerogenesis	3.323503e-9
GO:0009743	response to carbohydrate stimulus	3.874223e-9
GO:0007076	mitotic chromosome condensation	4.024532e-9
GO:0061162	establishment of monopolar cell polarity	4.074454e-9
GO:0051179	localization	4.121988e-9
GO:0009628	response to abiotic stimulus	4.189846e-9
GO:0031113	regulation of microtubule polymerization	6.953986e-9
GO:0032530	regulation of microvillus organization	7.443617e-9
GO:0047497	mitochondrion transport along microtubule	9.584226e-9
GO:0045109	intermediate filament organization	1.514157e-8
GO:0048246	macrophage chemotaxis	1.962268e-8
GO:0043267	negative regulation of potassium ion transport	3.694496e-8
GO:0032534	regulation of microvillus assembly	4.579893e-8
GO:0030317	sperm motility	5.018894e-8
GO:2000348	regulation of CD40 signaling pathway	5.501777e-8
GO:0030048	actin filament-based movement	6.556987e-8
GO:0044140	negative regulation of growth of symbiont on or near host surface	6.992240e-8
GO:0044130	negative regulation of growth of symbiont in host	7.680350e-8
GO:0035721	intraflagellar retrograde transport	8.648614e-8
GO:0031110	regulation of microtubule polymerization or depolymerization	8.841701e-8
GO:0043901	negative regulation of multi-organism process	1.142747e-7
GO:0051654	establishment of mitochondrion localization	1.328692e-7
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	1.429269e-7
GO:0002027	regulation of heart rate	2.124050e-7
GO:0000819	sister chromatid segregation	2.360000e-7
GO:0009612	response to mechanical stimulus	2.571973e-7
GO:0051932	synaptic transmission, GABAergic	2.763653e-7
GO:0015742	alpha-ketoglutarate transport	3.263114e-7
GO:0000070	mitotic sister chromatid segregation	3.295337e-7
GO:0015855	pyrimidine base transport	3.724151e-7
GO:0035458	cellular response to interferon-beta	4.319988e-7
GO:0007059	chromosome segregation	4.875526e-7
GO:0030049	muscle filament sliding	5.219508e-7
GO:0033189	response to vitamin A	5.241526e-7
GO:0051336	regulation of hydrolase activity	5.766079e-7
GO:0006970	response to osmotic stress	7.259134e-7
GO:0019509	L-methionine salvage from methylthioadenosine	7.457865e-7
GO:0007618	mating	8.256068e-7
GO:0015722	canalicular bile acid transport	8.637478e-7
GO:0042073	intraflagellar transport	8.872929e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	8.872929e-7
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	9.942977e-7
GO:0010836	negative regulation of protein ADP-ribosylation	1.175490e-6
GO:0070252	actin-mediated cell contraction	1.212987e-6
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.361642e-6
GO:0010863	positive regulation of phospholipase C activity	1.374555e-6
GO:0045214	sarcomere organization	1.692489e-6
GO:0006810	transport	1.729502e-6
GO:0007416	synapse assembly	1.731188e-6
GO:0071844	cellular component assembly at cellular level	2.186356e-6
GO:0002757	immune response-activating signal transduction	2.214730e-6
GO:0035871	protein K11-linked deubiquitination	2.319224e-6
GO:0002551	mast cell chemotaxis	2.319224e-6
GO:0043266	regulation of potassium ion transport	2.666996e-6
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.115129e-6
GO:0030241	skeletal muscle myosin thick filament assembly	3.376877e-6
GO:0022612	gland morphogenesis	3.433266e-6
GO:0031915	positive regulation of synaptic plasticity	3.514302e-6
GO:0035456	response to interferon-beta	3.819668e-6
GO:0050900	leukocyte migration	4.129444e-6
GO:0051234	establishment of localization	4.412014e-6
GO:0048870	cell motility	4.887774e-6
GO:0048739	cardiac muscle fiber development	5.131193e-6
GO:0050720	interleukin-1 beta biosynthetic process	5.448259e-6
GO:0034138	toll-like receptor 3 signaling pathway	5.539966e-6
GO:0070507	regulation of microtubule cytoskeleton organization	5.924192e-6
GO:0060193	positive regulation of lipase activity	6.235938e-6
GO:0010518	positive regulation of phospholipase activity	6.567865e-6
GO:0008361	regulation of cell size	6.920906e-6
GO:0070946	neutrophil mediated killing of gram-positive bacterium	7.017236e-6
GO:0001706	endoderm formation	7.121575e-6
GO:0045994	positive regulation of translational initiation by iron	7.257211e-6
GO:0002037	negative regulation of L-glutamate transport	7.257211e-6
GO:0032202	telomere assembly	7.355792e-6
GO:0035234	germ cell programmed cell death	8.855870e-6
GO:0045773	positive regulation of axon extension	9.210161e-6
GO:0010035	response to inorganic substance	9.828156e-6
GO:0007026	negative regulation of microtubule depolymerization	1.103108e-5
GO:0006955	immune response	1.149883e-5
GO:0055013	cardiac muscle cell development	1.152590e-5
GO:0051873	killing by host of symbiont cells	1.170287e-5
GO:0031103	axon regeneration	1.311170e-5
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.346575e-5
GO:0002221	pattern recognition receptor signaling pathway	1.347923e-5
GO:0046847	filopodium assembly	1.354585e-5
GO:0050830	defense response to Gram-positive bacterium	1.414770e-5
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.500666e-5
GO:0030516	regulation of axon extension	1.547121e-5
GO:0050435	beta-amyloid metabolic process	1.556850e-5
GO:0055085	transmembrane transport	1.588028e-5
GO:0002764	immune response-regulating signaling pathway	1.730247e-5
GO:0050790	regulation of catalytic activity	1.765575e-5
GO:0060299	negative regulation of sarcomere organization	1.821489e-5
GO:0033292	T-tubule organization	1.821489e-5
GO:0051023	regulation of immunoglobulin secretion	1.828980e-5
GO:0045161	neuronal ion channel clustering	1.971957e-5
GO:0042663	regulation of endodermal cell fate specification	1.999147e-5
GO:0002758	innate immune response-activating signal transduction	2.032561e-5
GO:0043271	negative regulation of ion transport	2.033184e-5
GO:0031114	regulation of microtubule depolymerization	2.056777e-5
GO:0070668	positive regulation of mast cell proliferation	2.133606e-5
GO:0006796	phosphate-containing compound metabolic process	2.172434e-5
GO:0001539	ciliary or flagellar motility	2.356653e-5
GO:0043200	response to amino acid stimulus	2.389722e-5
GO:0008625	induction of apoptosis via death domain receptors	2.409325e-5
GO:0031349	positive regulation of defense response	2.439746e-5
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	2.607339e-5
GO:0030240	skeletal muscle thin filament assembly	2.625668e-5
GO:0072531	pyrimidine-containing compound transmembrane transport	2.679369e-5
GO:0006323	DNA packaging	2.771287e-5
GO:0034220	ion transmembrane transport	2.782115e-5
GO:0006941	striated muscle contraction	2.852651e-5
GO:0065009	regulation of molecular function	2.889032e-5
GO:0010517	regulation of phospholipase activity	3.001089e-5
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.057819e-5
GO:0006863	purine base transport	3.062163e-5
GO:0014075	response to amine stimulus	3.068143e-5
GO:0007202	activation of phospholipase C activity	3.097441e-5
GO:0050896	response to stimulus	3.254713e-5
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	3.302452e-5
GO:0046689	response to mercury ion	3.348822e-5
GO:0070646	protein modification by small protein removal	3.433142e-5
GO:0033373	maintenance of protease location in mast cell secretory granule	3.509875e-5
GO:0033382	maintenance of granzyme B location in T cell secretory granule	3.509875e-5
GO:0030035	microspike assembly	3.762701e-5
GO:0009987	cellular process	3.764426e-5
GO:0071103	DNA conformation change	3.951921e-5
GO:0048675	axon extension	4.109971e-5
GO:0032878	regulation of establishment or maintenance of cell polarity	4.212844e-5
GO:0006447	regulation of translational initiation by iron	4.275759e-5
GO:0003008	system process	4.549483e-5
GO:0051495	positive regulation of cytoskeleton organization	4.616228e-5
GO:0072530	purine-containing compound transmembrane transport	4.705506e-5
GO:0045666	positive regulation of neuron differentiation	4.819737e-5
GO:0048584	positive regulation of response to stimulus	5.239039e-5
GO:0071286	cellular response to magnesium ion	5.260332e-5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5.344090e-5
GO:0015820	leucine transport	5.389831e-5
GO:0032273	positive regulation of protein polymerization	5.655262e-5
GO:0010243	response to organic nitrogen	5.658405e-5
GO:0055075	potassium ion homeostasis	6.038714e-5
GO:0015793	glycerol transport	6.038714e-5
GO:0061387	regulation of extent of cell growth	6.111818e-5
GO:0051956	negative regulation of amino acid transport	6.379919e-5
GO:0050778	positive regulation of immune response	6.419058e-5
GO:0042659	regulation of cell fate specification	6.564092e-5
GO:0051403	stress-activated MAPK cascade	6.602339e-5
GO:0000302	response to reactive oxygen species	7.394554e-5
GO:0031111	negative regulation of microtubule polymerization or depolymerization	7.679502e-5
GO:0002218	activation of innate immune response	7.727488e-5
GO:0033273	response to vitamin	7.932235e-5
GO:0097039	protein linear polyubiquitination	8.015057e-5
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	8.015057e-5
GO:0015851	nucleobase transport	8.066405e-5
GO:0046092	deoxycytidine metabolic process	8.087350e-5
GO:0034241	positive regulation of macrophage fusion	8.087350e-5
GO:0032074	negative regulation of nuclease activity	8.087350e-5
GO:0060191	regulation of lipase activity	8.345555e-5
GO:0048016	inositol phosphate-mediated signaling	8.783141e-5
GO:0042044	fluid transport	9.155378e-5
GO:0055008	cardiac muscle tissue morphogenesis	9.223647e-5
GO:0007181	transforming growth factor beta receptor complex assembly	9.241822e-5
GO:0070588	calcium ion transmembrane transport	9.369000e-5
GO:0030168	platelet activation	9.588546e-5
GO:0007600	sensory perception	9.953641e-5
GO:0009408	response to heat	1.051439e-4
GO:0055003	cardiac myofibril assembly	1.069187e-4
GO:2000114	regulation of establishment of cell polarity	1.069623e-4
GO:0032663	regulation of interleukin-2 production	1.091728e-4
GO:0040017	positive regulation of locomotion	1.101362e-4
GO:0032581	ER-dependent peroxisome organization	1.102553e-4
GO:0072181	mesonephric duct formation	1.134475e-4
GO:0002253	activation of immune response	1.138798e-4
GO:0006835	dicarboxylic acid transport	1.146668e-4
GO:0034104	negative regulation of tissue remodeling	1.234230e-4
GO:0034373	intermediate-density lipoprotein particle remodeling	1.241068e-4
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	1.249819e-4
GO:0048087	positive regulation of developmental pigmentation	1.301159e-4
GO:0042474	middle ear morphogenesis	1.305810e-4
GO:0006595	polyamine metabolic process	1.335194e-4
GO:0009750	response to fructose stimulus	1.379139e-4
GO:0032916	positive regulation of transforming growth factor beta3 production	1.505888e-4
GO:0032886	regulation of microtubule-based process	1.537879e-4
GO:0040032	post-embryonic body morphogenesis	1.562925e-4
GO:0022607	cellular component assembly	1.563659e-4
GO:0006936	muscle contraction	1.567740e-4
GO:0032879	regulation of localization	1.575482e-4
GO:0007154	cell communication	1.647649e-4
GO:0044342	type B pancreatic cell proliferation	1.648526e-4
GO:0010918	positive regulation of mitochondrial membrane potential	1.648526e-4
GO:0034638	phosphatidylcholine catabolic process	1.690635e-4
GO:0009067	aspartate family amino acid biosynthetic process	1.787299e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	1.789768e-4
GO:0006542	glutamine biosynthetic process	1.820054e-4
GO:0003012	muscle system process	1.830494e-4
GO:0031102	neuron projection regeneration	1.833847e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.854813e-4
GO:0000093	mitotic telophase	1.903003e-4
GO:0009086	methionine biosynthetic process	1.925409e-4
GO:0044085	cellular component biogenesis	1.965932e-4
GO:0043269	regulation of ion transport	1.997514e-4
GO:0008624	induction of apoptosis by extracellular signals	2.002884e-4
GO:0002268	follicular dendritic cell differentiation	2.013116e-4
GO:0051496	positive regulation of stress fiber assembly	2.022990e-4
GO:0045123	cellular extravasation	2.061605e-4
GO:0051532	regulation of NFAT protein import into nucleus	2.073722e-4
GO:0060117	auditory receptor cell development	2.079276e-4
GO:0045089	positive regulation of innate immune response	2.091198e-4
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	2.095775e-4
GO:0044111	development involved in symbiotic interaction	2.111618e-4
GO:0019089	transmission of virus	2.111618e-4
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	2.111618e-4
GO:0045779	negative regulation of bone resorption	2.147482e-4
GO:0033033	negative regulation of myeloid cell apoptosis	2.177027e-4
GO:0034382	chylomicron remnant clearance	2.243400e-4
GO:0051955	regulation of amino acid transport	2.267648e-4
GO:0034346	positive regulation of type III interferon production	2.270528e-4
GO:0001519	peptide amidation	2.292159e-4
GO:0015791	polyol transport	2.348011e-4
GO:0002036	regulation of L-glutamate transport	2.404934e-4
GO:0016579	protein deubiquitination	2.463597e-4
GO:0010623	developmental programmed cell death	2.480514e-4
GO:0035335	peptidyl-tyrosine dephosphorylation	2.482764e-4
GO:0051345	positive regulation of hydrolase activity	2.553098e-4
GO:0032211	negative regulation of telomere maintenance via telomerase	2.705317e-4
GO:0034284	response to monosaccharide stimulus	2.742485e-4
GO:0030335	positive regulation of cell migration	2.756790e-4
GO:0032501	multicellular organismal process	2.783496e-4
GO:2000147	positive regulation of cell motility	2.845566e-4
GO:0031581	hemidesmosome assembly	2.937319e-4
GO:0006144	purine base metabolic process	3.075551e-4
GO:0045356	positive regulation of interferon-alpha biosynthetic process	3.153487e-4
GO:0032224	positive regulation of synaptic transmission, cholinergic	3.185668e-4
GO:0033026	negative regulation of mast cell apoptosis	3.275203e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	3.347316e-4
GO:0040011	locomotion	3.374284e-4
GO:0001101	response to acid	3.377993e-4
GO:0007605	sensory perception of sound	3.393237e-4
GO:0051592	response to calcium ion	3.457395e-4
GO:0019255	glucose 1-phosphate metabolic process	3.467530e-4
GO:0032933	SREBP-mediated signaling pathway	3.585462e-4
GO:0051130	positive regulation of cellular component organization	3.601914e-4
GO:0060356	leucine import	3.637146e-4
GO:2000352	negative regulation of endothelial cell apoptosis	3.710128e-4
GO:0009886	post-embryonic morphogenesis	3.710791e-4
GO:0001578	microtubule bundle formation	3.743767e-4
GO:2000345	regulation of hepatocyte proliferation	3.802533e-4
GO:0034135	regulation of toll-like receptor 2 signaling pathway	4.017295e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	4.126180e-4
GO:0006586	indolalkylamine metabolic process	4.201451e-4
GO:0043589	skin morphogenesis	4.301835e-4
GO:0023052	signaling	4.359421e-4
GO:0042742	defense response to bacterium	4.366508e-4
GO:0050829	defense response to Gram-negative bacterium	4.366909e-4
GO:0042490	mechanoreceptor differentiation	4.517293e-4
GO:0010453	regulation of cell fate commitment	4.521106e-4
GO:0051049	regulation of transport	4.571712e-4
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	4.580287e-4
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	4.646767e-4
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	4.681817e-4
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	4.711873e-4
GO:0032845	negative regulation of homeostatic process	4.720743e-4
GO:0060119	inner ear receptor cell development	4.729826e-4
GO:0045636	positive regulation of melanocyte differentiation	4.777463e-4
GO:0002224	toll-like receptor signaling pathway	4.808624e-4
GO:0019722	calcium-mediated signaling	4.844111e-4
GO:0046887	positive regulation of hormone secretion	4.846809e-4
GO:0046835	carbohydrate phosphorylation	5.019694e-4
GO:0031346	positive regulation of cell projection organization	5.064041e-4
GO:0046629	gamma-delta T cell activation	5.075018e-4
GO:0007598	blood coagulation, extrinsic pathway	5.272357e-4
GO:0022603	regulation of anatomical structure morphogenesis	5.305367e-4
GO:0015914	phospholipid transport	5.317652e-4
GO:0009266	response to temperature stimulus	5.377733e-4
GO:0032675	regulation of interleukin-6 production	5.401313e-4
GO:0046851	negative regulation of bone remodeling	5.409977e-4
GO:0032859	activation of Ral GTPase activity	5.456105e-4
GO:0045579	positive regulation of B cell differentiation	5.477264e-4
GO:0006979	response to oxidative stress	5.575038e-4
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	5.587343e-4
GO:0046475	glycerophospholipid catabolic process	5.836047e-4
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	5.851505e-4
GO:0009896	positive regulation of catabolic process	5.898099e-4
GO:0007250	activation of NF-kappaB-inducing kinase activity	5.921778e-4
GO:0030030	cell projection organization	5.991736e-4
GO:0002093	auditory receptor cell morphogenesis	6.171820e-4
GO:0033632	regulation of cell-cell adhesion mediated by integrin	6.171820e-4
GO:0009746	response to hexose stimulus	6.258343e-4
GO:0031960	response to corticosteroid stimulus	6.538980e-4
GO:0006833	water transport	6.770871e-4
GO:0048660	regulation of smooth muscle cell proliferation	6.886130e-4
GO:0019227	neuronal action potential propagation	6.957358e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	6.997801e-4
GO:0002922	positive regulation of humoral immune response	7.010307e-4
GO:0006953	acute-phase response	7.043376e-4
GO:0051973	positive regulation of telomerase activity	7.059692e-4
GO:0042428	serotonin metabolic process	7.312538e-4
GO:0050878	regulation of body fluid levels	7.477093e-4
GO:0006468	protein phosphorylation	7.568882e-4
GO:0021870	Cajal-Retzius cell differentiation	7.692102e-4
GO:0010835	regulation of protein ADP-ribosylation	7.692102e-4
GO:0000097	sulfur amino acid biosynthetic process	7.931022e-4
GO:2000351	regulation of endothelial cell apoptosis	8.133192e-4
GO:0019441	tryptophan catabolic process to kynurenine	8.205278e-4
GO:0009611	response to wounding	8.248352e-4
GO:0001516	prostaglandin biosynthetic process	8.359207e-4
GO:0051646	mitochondrion localization	8.571104e-4
GO:0045948	positive regulation of translational initiation	8.579390e-4
GO:0050913	sensory perception of bitter taste	8.579390e-4
GO:2000347	positive regulation of hepatocyte proliferation	8.631355e-4
GO:0090291	negative regulation of osteoclast proliferation	8.631355e-4
GO:2000349	negative regulation of CD40 signaling pathway	8.631355e-4
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	8.631355e-4
GO:0072573	tolerance induction to lipopolysaccharide	8.631355e-4
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	8.631355e-4
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	8.631355e-4
GO:0045087	innate immune response	8.688981e-4
GO:0045740	positive regulation of DNA replication	8.769998e-4
GO:0072384	organelle transport along microtubule	8.819393e-4
GO:0042483	negative regulation of odontogenesis	8.913406e-4
GO:0046325	negative regulation of glucose import	9.025535e-4
GO:0007160	cell-matrix adhesion	9.055336e-4
GO:0071624	positive regulation of granulocyte chemotaxis	9.057821e-4
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	9.057821e-4
GO:0034122	negative regulation of toll-like receptor signaling pathway	9.155548e-4
GO:0006972	hyperosmotic response	9.155548e-4
GO:0032755	positive regulation of interleukin-6 production	9.195055e-4
GO:0045204	MAPK export from nucleus	9.239250e-4
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	9.239250e-4
GO:0015850	organic alcohol transport	9.241770e-4
GO:0006470	protein dephosphorylation	9.369975e-4
GO:0050789	regulation of biological process	9.523291e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	9.577611e-4
GO:0044258	intestinal lipid catabolic process	9.596369e-4
GO:0018350	protein esterification	9.596369e-4
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	9.610398e-4
GO:0050808	synapse organization	9.620340e-4
GO:0051716	cellular response to stimulus	9.647404e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	9.686471e-4
GO:0035105	sterol regulatory element binding protein import into nucleus	9.848231e-4
GO:0006642	triglyceride mobilization	1.007272e-3
GO:0010959	regulation of metal ion transport	1.010129e-3
GO:0042542	response to hydrogen peroxide	1.040824e-3
GO:0051057	positive regulation of small GTPase mediated signal transduction	1.053590e-3
GO:0002678	positive regulation of chronic inflammatory response	1.055977e-3
GO:0031099	regeneration	1.065840e-3
GO:0010638	positive regulation of organelle organization	1.071152e-3
GO:0016310	phosphorylation	1.075925e-3
GO:0031334	positive regulation of protein complex assembly	1.076029e-3
GO:0006811	ion transport	1.098413e-3
GO:0006575	cellular modified amino acid metabolic process	1.112716e-3
GO:0006590	thyroid hormone generation	1.115704e-3
GO:0044057	regulation of system process	1.116056e-3
GO:0017085	response to insecticide	1.129722e-3
GO:0016311	dephosphorylation	1.130991e-3
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	1.153800e-3
GO:2000627	positive regulation of miRNA catabolic process	1.153800e-3
GO:0010421	hydrogen peroxide-mediated programmed cell death	1.153800e-3
GO:0000964	mitochondrial RNA 5'-end processing	1.153800e-3
GO:0032910	regulation of transforming growth factor beta3 production	1.154697e-3
GO:0051591	response to cAMP	1.173742e-3
GO:0042491	auditory receptor cell differentiation	1.174309e-3
GO:0007599	hemostasis	1.184879e-3
GO:0007492	endoderm development	1.204883e-3
GO:0006693	prostaglandin metabolic process	1.209973e-3
GO:0032210	regulation of telomere maintenance via telomerase	1.213093e-3
GO:0043588	skin development	1.220604e-3
GO:0060415	muscle tissue morphogenesis	1.231922e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	1.235776e-3
GO:0030031	cell projection assembly	1.248626e-3
GO:0034446	substrate adhesion-dependent cell spreading	1.318866e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	1.327101e-3
GO:0031943	regulation of glucocorticoid metabolic process	1.327982e-3
GO:0039020	pronephric nephron tubule development	1.334654e-3
GO:0035565	regulation of pronephros size	1.334654e-3
GO:0071841	cellular component organization or biogenesis at cellular level	1.342117e-3
GO:0034134	toll-like receptor 2 signaling pathway	1.352474e-3
GO:0034130	toll-like receptor 1 signaling pathway	1.352474e-3
GO:0009894	regulation of catabolic process	1.356037e-3
GO:0001819	positive regulation of cytokine production	1.360815e-3
GO:0010171	body morphogenesis	1.365418e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	1.384244e-3
GO:0032989	cellular component morphogenesis	1.413485e-3
GO:0030104	water homeostasis	1.413679e-3
GO:0014866	skeletal myofibril assembly	1.420510e-3
GO:0050954	sensory perception of mechanical stimulus	1.455631e-3
GO:0048644	muscle organ morphogenesis	1.458102e-3
GO:0006111	regulation of gluconeogenesis	1.481922e-3
GO:0006275	regulation of DNA replication	1.540029e-3
GO:0035630	bone mineralization involved in bone maturation	1.549664e-3
GO:0070375	BMK cascade	1.594964e-3
GO:0048588	developmental cell growth	1.612116e-3
GO:0051272	positive regulation of cellular component movement	1.653092e-3
GO:0007010	cytoskeleton organization	1.666986e-3
GO:0032924	activin receptor signaling pathway	1.677782e-3
GO:0060088	auditory receptor cell stereocilium organization	1.686858e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.697311e-3
GO:0060122	inner ear receptor stereocilium organization	1.726078e-3
GO:0006354	transcription elongation, DNA-dependent	1.759539e-3
GO:0016337	cell-cell adhesion	1.762833e-3
GO:0071842	cellular component organization at cellular level	1.767293e-3
GO:0070861	regulation of protein exit from endoplasmic reticulum	1.769038e-3
GO:0007596	blood coagulation	1.778454e-3
GO:0048639	positive regulation of developmental growth	1.778594e-3
GO:0030967	ER-nuclear sterol response pathway	1.785449e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	1.801541e-3
GO:0065007	biological regulation	1.851352e-3
GO:0007584	response to nutrient	1.860495e-3
GO:0045634	regulation of melanocyte differentiation	1.884986e-3
GO:0019229	regulation of vasoconstriction	1.910047e-3
GO:0034694	response to prostaglandin stimulus	1.921813e-3
GO:0046579	positive regulation of Ras protein signal transduction	1.921978e-3
GO:0031329	regulation of cellular catabolic process	1.926586e-3
GO:0048729	tissue morphogenesis	1.937340e-3
GO:0015884	folic acid transport	1.965849e-3
GO:0043402	glucocorticoid mediated signaling pathway	2.019885e-3
GO:0006464	protein modification process	2.042565e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	2.053872e-3
GO:0070943	neutrophil mediated killing of symbiont cell	2.065823e-3
GO:0071840	cellular component organization or biogenesis	2.068723e-3
GO:0048245	eosinophil chemotaxis	2.085472e-3
GO:0000165	MAPKKK cascade	2.130618e-3
GO:0070189	kynurenine metabolic process	2.157222e-3
GO:0007190	activation of adenylate cyclase activity	2.269674e-3
GO:0051050	positive regulation of transport	2.300811e-3
GO:0031281	positive regulation of cyclase activity	2.302433e-3
GO:0034372	very-low-density lipoprotein particle remodeling	2.309018e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	2.311341e-3
GO:2000001	regulation of DNA damage checkpoint	2.317593e-3
GO:0043900	regulation of multi-organism process	2.322300e-3
GO:0048814	regulation of dendrite morphogenesis	2.342177e-3
GO:0051953	negative regulation of amine transport	2.359419e-3
GO:0070741	response to interleukin-6	2.373767e-3
GO:0021509	roof plate formation	2.389747e-3
GO:0048701	embryonic cranial skeleton morphogenesis	2.394496e-3
GO:0009236	cobalamin biosynthetic process	2.397095e-3
GO:0006994	positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	2.397095e-3
GO:0045670	regulation of osteoclast differentiation	2.428020e-3
GO:0006692	prostanoid metabolic process	2.472562e-3
GO:0031652	positive regulation of heat generation	2.495895e-3
GO:0010459	negative regulation of heart rate	2.504910e-3
GO:0043088	regulation of Cdc42 GTPase activity	2.529262e-3
GO:0032388	positive regulation of intracellular transport	2.532392e-3
GO:0061099	negative regulation of protein tyrosine kinase activity	2.570998e-3
GO:0070328	triglyceride homeostasis	2.570998e-3
GO:0006641	triglyceride metabolic process	2.650975e-3
GO:0045762	positive regulation of adenylate cyclase activity	2.674848e-3
GO:0022601	menstrual cycle phase	2.686333e-3
GO:0045732	positive regulation of protein catabolic process	2.705659e-3
GO:0007017	microtubule-based process	2.716407e-3
GO:0008156	negative regulation of DNA replication	2.730590e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	2.758924e-3
GO:0032026	response to magnesium ion	2.762884e-3
GO:0031344	regulation of cell projection organization	2.861283e-3
GO:0018065	protein-cofactor linkage	2.892471e-3
GO:0030431	sleep	2.896872e-3
GO:0032728	positive regulation of interferon-beta production	2.913795e-3
GO:0032494	response to peptidoglycan	2.926037e-3
GO:0070884	regulation of calcineurin-NFAT signaling pathway	2.956709e-3
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	2.965809e-3
GO:0030208	dermatan sulfate biosynthetic process	2.997757e-3
GO:0051349	positive regulation of lyase activity	3.009162e-3
GO:0000188	inactivation of MAPK activity	3.022644e-3
GO:0060341	regulation of cellular localization	3.088446e-3
GO:0051128	regulation of cellular component organization	3.131543e-3
GO:0002832	negative regulation of response to biotic stimulus	3.135151e-3
GO:0043412	macromolecule modification	3.143545e-3
GO:0007606	sensory perception of chemical stimulus	3.149512e-3
GO:0046324	regulation of glucose import	3.164444e-3
GO:0006907	pinocytosis	3.203782e-3
GO:0090207	regulation of triglyceride metabolic process	3.224444e-3
GO:0018126	protein hydroxylation	3.270756e-3
GO:0001817	regulation of cytokine production	3.287296e-3
GO:0045078	positive regulation of interferon-gamma biosynthetic process	3.287994e-3
GO:0048266	behavioral response to pain	3.287994e-3
GO:0034121	regulation of toll-like receptor signaling pathway	3.321519e-3
GO:0042159	lipoprotein catabolic process	3.361749e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	9.549667e-24
GO:0006581	acetylcholine catabolic process	2.712461e-14
GO:0008291	acetylcholine metabolic process	6.521114e-14
GO:0045212	neurotransmitter receptor biosynthetic process	3.100848e-11
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	4.495186e-11
GO:0045213	neurotransmitter receptor metabolic process	5.000006e-11
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	2.387918e-10
GO:0010744	positive regulation of macrophage derived foam cell differentiation	5.432406e-10
GO:0010886	positive regulation of cholesterol storage	1.143901e-9
GO:0046108	uridine metabolic process	3.338170e-9
GO:0042135	neurotransmitter catabolic process	3.481100e-9
GO:0010884	positive regulation of lipid storage	6.604337e-9
GO:0009566	fertilization	1.149770e-8
GO:0046709	IDP catabolic process	1.274077e-8
GO:0046032	ADP catabolic process	1.274077e-8
GO:0010885	regulation of cholesterol storage	1.624077e-8
GO:0070977	bone maturation	2.338857e-8
GO:0048515	spermatid differentiation	3.790438e-8
GO:0010743	regulation of macrophage derived foam cell differentiation	4.198651e-8
GO:0043931	ossification involved in bone maturation	4.410652e-8
GO:0042742	defense response to bacterium	1.094986e-7
GO:0001919	regulation of receptor recycling	1.408000e-7
GO:0070079	histone H4-R3 demethylation	1.528788e-7
GO:0070078	histone H3-R2 demethylation	1.528788e-7
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.528788e-7
GO:0021700	developmental maturation	2.042571e-7
GO:0006897	endocytosis	2.508395e-7
GO:0044341	sodium-dependent phosphate transport	2.807144e-7
GO:0009181	purine ribonucleoside diphosphate catabolic process	2.807144e-7
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3.428529e-7
GO:0034383	low-density lipoprotein particle clearance	3.972121e-7
GO:0071379	cellular response to prostaglandin stimulus	4.145586e-7
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	4.875191e-7
GO:0007286	spermatid development	4.881802e-7
GO:0014904	myotube cell development	4.971909e-7
GO:0048009	insulin-like growth factor receptor signaling pathway	5.038980e-7
GO:0048745	smooth muscle tissue development	6.410607e-7
GO:0048286	lung alveolus development	6.488178e-7
GO:0048844	artery morphogenesis	8.388746e-7
GO:0048469	cell maturation	9.669685e-7
GO:0030643	cellular phosphate ion homeostasis	1.355341e-6
GO:0042159	lipoprotein catabolic process	1.431581e-6
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1.533519e-6
GO:0035630	bone mineralization involved in bone maturation	1.545715e-6
GO:0071874	cellular response to norepinephrine stimulus	1.638941e-6
GO:0034694	response to prostaglandin stimulus	1.862408e-6
GO:0060840	artery development	1.948483e-6
GO:0090201	negative regulation of release of cytochrome c from mitochondria	2.207645e-6
GO:0002344	B cell affinity maturation	2.827582e-6
GO:0042953	lipoprotein transport	3.117980e-6
GO:0042133	neurotransmitter metabolic process	3.249120e-6
GO:0060509	Type I pneumocyte differentiation	3.317236e-6
GO:0046602	regulation of mitotic centrosome separation	3.466415e-6
GO:0000917	barrier septum formation	3.466415e-6
GO:0045333	cellular respiration	3.726532e-6
GO:0010823	negative regulation of mitochondrion organization	3.847707e-6
GO:0055062	phosphate ion homeostasis	3.916845e-6
GO:0050935	iridophore differentiation	4.041319e-6
GO:0048937	lateral line nerve glial cell development	4.041319e-6
GO:0046031	ADP metabolic process	4.263626e-6
GO:0040011	locomotion	5.399695e-6
GO:0009179	purine ribonucleoside diphosphate metabolic process	6.518400e-6
GO:0050679	positive regulation of epithelial cell proliferation	6.648986e-6
GO:0006810	transport	6.778852e-6
GO:0060741	prostate gland stromal morphogenesis	7.438749e-6
GO:0046604	positive regulation of mitotic centrosome separation	7.517559e-6
GO:0015980	energy derivation by oxidation of organic compounds	8.704184e-6
GO:0021936	regulation of cerebellar granule cell precursor proliferation	9.280324e-6
GO:0002268	follicular dendritic cell differentiation	9.877246e-6
GO:0007271	synaptic transmission, cholinergic	9.926594e-6
GO:0051262	protein tetramerization	1.088827e-5
GO:0019695	choline metabolic process	1.217589e-5
GO:0071870	cellular response to catecholamine stimulus	1.257505e-5
GO:0060510	Type II pneumocyte differentiation	1.332621e-5
GO:0009957	epidermal cell fate specification	1.466383e-5
GO:0006910	phagocytosis, recognition	2.152691e-5
GO:0045796	negative regulation of intestinal cholesterol absorption	2.354021e-5
GO:0010949	negative regulation of intestinal phytosterol absorption	2.354021e-5
GO:0051234	establishment of localization	2.437801e-5
GO:0060100	positive regulation of phagocytosis, engulfment	2.593104e-5
GO:0043654	recognition of apoptotic cell	2.617681e-5
GO:0048846	axon extension involved in axon guidance	2.863209e-5
GO:0048878	chemical homeostasis	3.135314e-5
GO:0006817	phosphate ion transport	3.156809e-5
GO:0051259	protein oligomerization	3.340717e-5
GO:0010001	glial cell differentiation	3.450175e-5
GO:0042592	homeostatic process	3.517131e-5
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	3.813739e-5
GO:0042375	quinone cofactor metabolic process	4.092357e-5
GO:0006213	pyrimidine nucleoside metabolic process	4.126584e-5
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	4.395630e-5
GO:0055081	anion homeostasis	4.571908e-5
GO:0006414	translational elongation	4.587452e-5
GO:0034392	negative regulation of smooth muscle cell apoptosis	4.735388e-5
GO:0060426	lung vasculature development	5.096100e-5
GO:0070245	positive regulation of thymocyte apoptosis	5.139419e-5
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	5.382263e-5
GO:0046579	positive regulation of Ras protein signal transduction	5.470198e-5
GO:0002475	antigen processing and presentation via MHC class Ib	5.620327e-5
GO:0042402	cellular biogenic amine catabolic process	6.411677e-5
GO:0016044	cellular membrane organization	6.848324e-5
GO:0002339	B cell selection	6.868757e-5
GO:0032800	receptor biosynthetic process	6.965284e-5
GO:0045426	quinone cofactor biosynthetic process	6.967755e-5
GO:0034381	plasma lipoprotein particle clearance	7.165079e-5
GO:0048468	cell development	7.460403e-5
GO:0007281	germ cell development	7.706830e-5
GO:0061024	membrane organization	7.712653e-5
GO:0006811	ion transport	7.783128e-5
GO:0030818	negative regulation of cAMP biosynthetic process	7.843633e-5
GO:0030301	cholesterol transport	7.890219e-5
GO:0032878	regulation of establishment or maintenance of cell polarity	7.970358e-5
GO:0009191	ribonucleoside diphosphate catabolic process	7.970358e-5
GO:0031017	exocrine pancreas development	7.990020e-5
GO:0009636	response to toxin	7.993540e-5
GO:0045980	negative regulation of nucleotide metabolic process	8.339382e-5
GO:0009310	amine catabolic process	8.347618e-5
GO:0009314	response to radiation	8.386765e-5
GO:0006642	triglyceride mobilization	8.726306e-5
GO:0007283	spermatogenesis	8.755951e-5
GO:0009416	response to light stimulus	9.051130e-5
GO:0070234	positive regulation of T cell apoptosis	9.196105e-5
GO:0006939	smooth muscle contraction	9.319611e-5
GO:0071396	cellular response to lipid	9.386027e-5
GO:0072643	interferon-gamma secretion	9.407269e-5
GO:0072608	interleukin-10 secretion	9.407269e-5
GO:0090198	negative regulation of chemokine secretion	9.407269e-5
GO:0035926	chemokine (C-C motif) ligand 2 secretion	9.407269e-5
GO:0043311	positive regulation of eosinophil degranulation	9.407269e-5
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	9.407269e-5
GO:0071695	anatomical structure maturation	9.931452e-5
GO:0048610	cellular process involved in reproduction	1.090179e-4
GO:0034374	low-density lipoprotein particle remodeling	1.099477e-4
GO:0051726	regulation of cell cycle	1.117007e-4
GO:0006461	protein complex assembly	1.119721e-4
GO:0030002	cellular anion homeostasis	1.135820e-4
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	1.142526e-4
GO:0007416	synapse assembly	1.204095e-4
GO:0043933	macromolecular complex subunit organization	1.230303e-4
GO:0070271	protein complex biogenesis	1.341481e-4
GO:0048548	regulation of pinocytosis	1.371912e-4
GO:0007422	peripheral nervous system development	1.415318e-4
GO:0048880	sensory system development	1.416354e-4
GO:0051179	localization	1.420489e-4
GO:0048857	neural nucleus development	1.427383e-4
GO:0042119	neutrophil activation	1.447947e-4
GO:0009134	nucleoside diphosphate catabolic process	1.447947e-4
GO:0060457	negative regulation of digestive system process	1.452541e-4
GO:0010741	negative regulation of intracellular protein kinase cascade	1.509461e-4
GO:0009791	post-embryonic development	1.538876e-4
GO:0019882	antigen processing and presentation	1.629772e-4
GO:0001516	prostaglandin biosynthetic process	1.693704e-4
GO:0046329	negative regulation of JNK cascade	1.725371e-4
GO:0006467	protein thiol-disulfide exchange	1.795928e-4
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	1.942300e-4
GO:0061181	regulation of chondrocyte development	2.065889e-4
GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	2.065889e-4
GO:0042697	menopause	2.105828e-4
GO:0001660	fever generation	2.105828e-4
GO:0001990	regulation of systemic arterial blood pressure by hormone	2.115004e-4
GO:0007088	regulation of mitosis	2.189648e-4
GO:0033762	response to glucagon stimulus	2.214020e-4
GO:0019884	antigen processing and presentation of exogenous antigen	2.430529e-4
GO:0071822	protein complex subunit organization	2.529369e-4
GO:0043255	regulation of carbohydrate biosynthetic process	2.591230e-4
GO:0010625	positive regulation of Schwann cell proliferation	2.615642e-4
GO:0048609	multicellular organismal reproductive process	2.621346e-4
GO:0050663	cytokine secretion	2.662305e-4
GO:0006744	ubiquinone biosynthetic process	2.711148e-4
GO:0018126	protein hydroxylation	2.764301e-4
GO:0009185	ribonucleoside diphosphate metabolic process	2.778004e-4
GO:0002741	positive regulation of cytokine secretion involved in immune response	2.879219e-4
GO:0032930	positive regulation of superoxide anion generation	2.879219e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.954269e-4
GO:0014896	muscle hypertrophy	2.963825e-4
GO:0032902	nerve growth factor production	2.973565e-4
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	2.976815e-4
GO:0014031	mesenchymal cell development	3.063949e-4
GO:0046131	pyrimidine ribonucleoside metabolic process	3.074946e-4
GO:0035272	exocrine system development	3.184469e-4
GO:0060017	parathyroid gland development	3.255598e-4
GO:0051823	regulation of synapse structural plasticity	3.255598e-4
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	3.484850e-4
GO:0002019	regulation of renal output by angiotensin	3.644242e-4
GO:0071702	organic substance transport	3.796773e-4
GO:0055096	low-density lipoprotein particle mediated signaling	3.825521e-4
GO:0071221	cellular response to bacterial lipopeptide	3.857460e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	3.950864e-4
GO:0003014	renal system process	3.954018e-4
GO:0002639	positive regulation of immunoglobulin production	4.054415e-4
GO:0006820	anion transport	4.393022e-4
GO:0045725	positive regulation of glycogen biosynthetic process	4.448904e-4
GO:0048708	astrocyte differentiation	4.485188e-4
GO:0051057	positive regulation of small GTPase mediated signal transduction	4.518761e-4
GO:0007588	excretion	4.546132e-4
GO:0045794	negative regulation of cell volume	4.550635e-4
GO:0010464	regulation of mesenchymal cell proliferation	4.559024e-4
GO:0007221	positive regulation of transcription of Notch receptor target	4.585517e-4
GO:0006869	lipid transport	4.674908e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	4.739206e-4
GO:0010044	response to aluminum ion	4.739206e-4
GO:0015698	inorganic anion transport	4.964367e-4
GO:0048732	gland development	5.052569e-4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	5.204517e-4
GO:0006102	isocitrate metabolic process	5.302123e-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.345821e-4
GO:0071346	cellular response to interferon-gamma	5.455289e-4
GO:0006378	mRNA polyadenylation	5.505636e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	5.587188e-4
GO:0010656	negative regulation of muscle cell apoptosis	5.605561e-4
GO:0010676	positive regulation of cellular carbohydrate metabolic process	5.754185e-4
GO:0006952	defense response	5.762314e-4
GO:0090322	regulation of superoxide metabolic process	5.876416e-4
GO:0042063	gliogenesis	5.890346e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	5.902929e-4
GO:0090212	negative regulation of establishment of blood-brain barrier	5.902929e-4
GO:0007285	primary spermatocyte growth	5.902929e-4
GO:0010883	regulation of lipid storage	6.327409e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	6.399885e-4
GO:0009116	nucleoside metabolic process	6.401703e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	6.445596e-4
GO:0046607	positive regulation of centrosome cycle	7.054295e-4
GO:0021935	cerebellar granule cell precursor tangential migration	7.054295e-4
GO:0071805	potassium ion transmembrane transport	7.101672e-4
GO:0048588	developmental cell growth	7.211093e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	7.249410e-4
GO:0043409	negative regulation of MAPKKK cascade	7.263539e-4
GO:0042428	serotonin metabolic process	7.698508e-4
GO:0009119	ribonucleoside metabolic process	8.119943e-4
GO:0070243	regulation of thymocyte apoptosis	8.344873e-4
GO:0003006	developmental process involved in reproduction	8.393590e-4
GO:0010863	positive regulation of phospholipase C activity	8.544240e-4
GO:0060992	response to fungicide	8.697811e-4
GO:0002827	positive regulation of T-helper 1 type immune response	8.880705e-4
GO:0071072	negative regulation of phospholipid biosynthetic process	9.003259e-4
GO:0033085	negative regulation of T cell differentiation in thymus	9.089942e-4
GO:0043045	DNA methylation involved in embryo development	9.702722e-4
GO:0072321	chaperone-mediated protein transport	9.713522e-4
GO:0007276	gamete generation	9.727700e-4
GO:0050896	response to stimulus	1.010833e-3
GO:0030282	bone mineralization	1.029024e-3
GO:0050678	regulation of epithelial cell proliferation	1.049845e-3
GO:0009072	aromatic amino acid family metabolic process	1.051754e-3
GO:0032940	secretion by cell	1.070776e-3
GO:0061036	positive regulation of cartilage development	1.094453e-3
GO:0045840	positive regulation of mitosis	1.101946e-3
GO:0014910	regulation of smooth muscle cell migration	1.110173e-3
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	1.124088e-3
GO:0010907	positive regulation of glucose metabolic process	1.129035e-3
GO:0021983	pituitary gland development	1.137893e-3
GO:0009750	response to fructose stimulus	1.159081e-3
GO:0022904	respiratory electron transport chain	1.160012e-3
GO:0031649	heat generation	1.206405e-3
GO:0005979	regulation of glycogen biosynthetic process	1.220310e-3
GO:0014911	positive regulation of smooth muscle cell migration	1.226619e-3
GO:0048002	antigen processing and presentation of peptide antigen	1.243776e-3
GO:0048549	positive regulation of pinocytosis	1.253107e-3
GO:0060601	lateral sprouting from an epithelium	1.270538e-3
GO:0060513	prostatic bud formation	1.293755e-3
GO:0032928	regulation of superoxide anion generation	1.296712e-3
GO:0008228	opsonization	1.315519e-3
GO:2000179	positive regulation of neural precursor cell proliferation	1.323236e-3
GO:0009060	aerobic respiration	1.361697e-3
GO:0015936	coenzyme A metabolic process	1.399919e-3
GO:0042439	ethanolamine-containing compound metabolic process	1.404829e-3
GO:0071071	regulation of phospholipid biosynthetic process	1.424666e-3
GO:0022409	positive regulation of cell-cell adhesion	1.443614e-3
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1.469128e-3
GO:0042297	vocal learning	1.486113e-3
GO:0046541	saliva secretion	1.491318e-3
GO:0032713	negative regulation of interleukin-4 production	1.500873e-3
GO:0034763	negative regulation of transmembrane transport	1.579327e-3
GO:0007214	gamma-aminobutyric acid signaling pathway	1.593258e-3
GO:0071478	cellular response to radiation	1.600403e-3
GO:0019953	sexual reproduction	1.634351e-3
GO:0006457	protein folding	1.656999e-3
GO:0009605	response to external stimulus	1.704096e-3
GO:0007530	sex determination	1.707656e-3
GO:0065003	macromolecular complex assembly	1.728159e-3
GO:2000484	positive regulation of interleukin-8 secretion	1.780825e-3
GO:0060157	urinary bladder development	1.799929e-3
GO:0019433	triglyceride catabolic process	1.817116e-3
GO:0014002	astrocyte development	1.829045e-3
GO:0043277	apoptotic cell clearance	1.831291e-3
GO:0050789	regulation of biological process	1.866673e-3
GO:0045821	positive regulation of glycolysis	1.901555e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.906069e-3
GO:0071425	hemopoietic stem cell proliferation	1.987389e-3
GO:0030263	apoptotic chromosome condensation	2.002754e-3
GO:0032613	interleukin-10 production	2.002754e-3
GO:0003100	regulation of systemic arterial blood pressure by endothelin	2.005117e-3
GO:0006140	regulation of nucleotide metabolic process	2.010727e-3
GO:0014821	phasic smooth muscle contraction	2.024123e-3
GO:0065007	biological regulation	2.128613e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	2.141627e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.188865e-3
GO:0060082	eye blink reflex	2.193965e-3
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	2.198310e-3
GO:0042330	taxis	2.215342e-3
GO:0050770	regulation of axonogenesis	2.286691e-3
GO:0034369	plasma lipoprotein particle remodeling	2.341683e-3
GO:0010827	regulation of glucose transport	2.399907e-3
GO:0034123	positive regulation of toll-like receptor signaling pathway	2.406253e-3
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	2.413971e-3
GO:0060445	branching involved in salivary gland morphogenesis	2.445562e-3
GO:0042632	cholesterol homeostasis	2.455200e-3
GO:0007632	visual behavior	2.461985e-3
GO:0050801	ion homeostasis	2.487480e-3
GO:2000334	positive regulation of blood microparticle formation	2.492316e-3
GO:0001701	in utero embryonic development	2.495700e-3
GO:0043631	RNA polyadenylation	2.519624e-3
GO:0009306	protein secretion	2.531139e-3
GO:0051968	positive regulation of synaptic transmission, glutamatergic	2.539627e-3
GO:0030104	water homeostasis	2.549787e-3
GO:0009082	branched chain family amino acid biosynthetic process	2.582147e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	2.582147e-3
GO:0046501	protoporphyrinogen IX metabolic process	2.599481e-3
GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	2.599481e-3
GO:0009584	detection of visible light	2.620112e-3
GO:0001942	hair follicle development	2.639222e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	2.640613e-3
GO:0040009	regulation of growth rate	2.642584e-3
GO:0032369	negative regulation of lipid transport	2.690314e-3
GO:0048016	inositol phosphate-mediated signaling	2.731167e-3
GO:0051216	cartilage development	2.806026e-3
GO:0060428	lung epithelium development	2.809003e-3
GO:0055114	oxidation-reduction process	2.827887e-3
GO:0001952	regulation of cell-matrix adhesion	2.839110e-3
GO:0050886	endocrine process	2.932142e-3
GO:0006935	chemotaxis	2.947300e-3
GO:0097029	mature dendritic cell differentiation	3.008986e-3
GO:0043309	regulation of eosinophil degranulation	3.008986e-3
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	3.008986e-3
GO:0055088	lipid homeostasis	3.040580e-3
GO:0006826	iron ion transport	3.081848e-3
GO:0032855	positive regulation of Rac GTPase activity	3.096369e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	3.105446e-3
GO:0032696	negative regulation of interleukin-13 production	3.126874e-3
GO:0046503	glycerolipid catabolic process	3.141389e-3
GO:0019067	viral assembly, maturation, egress, and release	3.144184e-3
GO:0021782	glial cell development	3.213893e-3
GO:0016049	cell growth	3.220774e-3
GO:0043570	maintenance of DNA repeat elements	3.221066e-3
GO:0043403	skeletal muscle tissue regeneration	3.279397e-3
GO:0046823	negative regulation of nucleocytoplasmic transport	3.283774e-3
GO:0002700	regulation of production of molecular mediator of immune response	3.287851e-3
GO:0048485	sympathetic nervous system development	3.295654e-3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.320175e-3
GO:0021629	olfactory nerve structural organization	3.320175e-3
GO:0033993	response to lipid	3.347119e-3
GO:0010595	positive regulation of endothelial cell migration	3.472398e-3
GO:0033205	cell cycle cytokinesis	3.486257e-3
GO:0042633	hair cycle	3.550145e-3
GO:0060740	prostate gland epithelium morphogenesis	3.603338e-3
GO:0046887	positive regulation of hormone secretion	3.604043e-3
GO:0030850	prostate gland development	3.644140e-3
GO:0010627	regulation of intracellular protein kinase cascade	3.652469e-3
GO:0010624	regulation of Schwann cell proliferation	3.738966e-3
GO:0006729	tetrahydrobiopterin biosynthetic process	3.738966e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	3.748939e-3
GO:0014850	response to muscle activity	3.770332e-3
GO:0070875	positive regulation of glycogen metabolic process	3.782055e-3
GO:0046605	regulation of centrosome cycle	3.842971e-3
GO:0070371	ERK1 and ERK2 cascade	3.877902e-3
GO:0010518	positive regulation of phospholipase activity	3.882416e-3
GO:0045540	regulation of cholesterol biosynthetic process	3.923374e-3
GO:0019722	calcium-mediated signaling	3.938323e-3
GO:0023056	positive regulation of signaling	3.970385e-3
GO:0060512	prostate gland morphogenesis	4.070178e-3
GO:0060547	negative regulation of necrotic cell death	4.080388e-3
GO:0030534	adult behavior	4.083438e-3
GO:0002016	regulation of blood volume by renin-angiotensin	4.155900e-3
GO:0070340	detection of bacterial lipopeptide	4.159476e-3
GO:0015734	taurine transport	4.159476e-3
GO:0070383	DNA cytosine deamination	4.179598e-3
GO:0010529	negative regulation of transposition	4.179598e-3
GO:0051000	positive regulation of nitric-oxide synthase activity	4.209613e-3
GO:0001755	neural crest cell migration	4.236876e-3
GO:0006884	cell volume homeostasis	4.246222e-3
GO:0006693	prostaglandin metabolic process	4.256797e-3
GO:0019827	stem cell maintenance	4.277772e-3
GO:0001938	positive regulation of endothelial cell proliferation	4.334177e-3
GO:0017158	regulation of calcium ion-dependent exocytosis	4.387652e-3
GO:0061156	pulmonary artery morphogenesis	4.404366e-3
GO:0071402	cellular response to lipoprotein particle stimulus	4.411372e-3
GO:0001829	trophectodermal cell differentiation	4.419108e-3
GO:0090340	positive regulation of secretion of lysosomal enzymes	4.459315e-3
GO:0090187	positive regulation of pancreatic juice secretion	4.459315e-3
GO:0090108	positive regulation of high-density lipoprotein particle assembly	4.459315e-3
GO:0006393	termination of mitochondrial transcription	4.459315e-3
GO:0031118	rRNA pseudouridine synthesis	4.459315e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	4.479566e-3
GO:0061049	cell growth involved in cardiac muscle cell development	4.479566e-3
GO:0008065	establishment of blood-nerve barrier	4.479566e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	4.479566e-3
GO:0031124	mRNA 3'-end processing	4.505870e-3
GO:0015810	aspartate transport	4.609847e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	4.686002e-3
GO:0010828	positive regulation of glucose transport	4.728001e-3
GO:0070232	regulation of T cell apoptosis	4.750192e-3
GO:0007202	activation of phospholipase C activity	4.923995e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	4.927261e-3
GO:0003073	regulation of systemic arterial blood pressure	4.992073e-3
GO:0060736	prostate gland growth	5.005548e-3
GO:0071615	oxidative deethylation	5.107076e-3
GO:0035048	splicing factor protein import into nucleus	5.107076e-3
GO:0009403	toxin biosynthetic process	5.107076e-3
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	5.157085e-3
GO:0031987	locomotion involved in locomotory behavior	5.157085e-3
GO:0060009	Sertoli cell development	5.161986e-3
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	5.186561e-3
GO:0070166	enamel mineralization	5.192728e-3
GO:0061088	regulation of sequestering of zinc ion	5.192728e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	5.192728e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	5.192728e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	5.260310e-3
GO:0043488	regulation of mRNA stability	5.327720e-3
GO:0046464	acylglycerol catabolic process	5.369305e-3
GO:0014032	neural crest cell development	5.375556e-3
GO:0048512	circadian behavior	5.437005e-3
GO:0021952	central nervous system projection neuron axonogenesis	5.440671e-3
GO:0001954	positive regulation of cell-matrix adhesion	5.440671e-3
GO:0035520	monoubiquitinated protein deubiquitination	5.445820e-3
GO:0030299	intestinal cholesterol absorption	5.462296e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	5.532511e-3
GO:0010647	positive regulation of cell communication	5.553002e-3
GO:0070230	positive regulation of lymphocyte apoptosis	5.596671e-3
GO:0046903	secretion	5.661068e-3
GO:0042221	response to chemical stimulus	5.702913e-3
GO:0010039	response to iron ion	5.729825e-3
GO:0046835	carbohydrate phosphorylation	5.822452e-3
GO:0051966	regulation of synaptic transmission, glutamatergic	5.885913e-3
GO:0048820	hair follicle maturation	5.892056e-3
GO:0006812	cation transport	6.032696e-3
GO:0008542	visual learning	6.061401e-3
GO:0060487	lung epithelial cell differentiation	6.105834e-3
GO:0009912	auditory receptor cell fate commitment	6.106248e-3
GO:0060479	lung cell differentiation	6.133053e-3
GO:0061113	pancreas morphogenesis	6.183683e-3
GO:0031223	auditory behavior	6.183683e-3
GO:0035019	somatic stem cell maintenance	6.213711e-3
GO:0009583	detection of light stimulus	6.225838e-3
GO:0033865	nucleoside bisphosphate metabolic process	6.337715e-3
GO:2000191	regulation of fatty acid transport	6.339138e-3
GO:0032602	chemokine production	6.366634e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	6.366634e-3
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	6.366634e-3
GO:0021785	branchiomotor neuron axon guidance	6.374615e-3
GO:0002018	renin-angiotensin regulation of aldosterone production	6.374615e-3
GO:0001944	vasculature development	6.454534e-3
GO:0048870	cell motility	6.465974e-3
GO:0010564	regulation of cell cycle process	6.498822e-3
GO:0034391	regulation of smooth muscle cell apoptosis	6.521170e-3
GO:0070873	regulation of glycogen metabolic process	6.552159e-3
GO:0031345	negative regulation of cell projection organization	6.637651e-3
GO:0055072	iron ion homeostasis	6.691524e-3
GO:0017145	stem cell division	6.715272e-3
GO:0045109	intermediate filament organization	6.749419e-3
GO:0046328	regulation of JNK cascade	6.774738e-3
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	6.925548e-3
GO:0001764	neuron migration	6.939842e-3
GO:0046219	indolalkylamine biosynthetic process	6.952897e-3
GO:0070295	renal water absorption	6.952897e-3
GO:0042427	serotonin biosynthetic process	6.952897e-3
GO:0001514	selenocysteine incorporation	6.989295e-3
GO:0060486	Clara cell differentiation	7.030413e-3
GO:0006576	cellular biogenic amine metabolic process	7.179704e-3
GO:0035270	endocrine system development	7.194965e-3
GO:0060073	micturition	7.237518e-3
GO:0008643	carbohydrate transport	7.251475e-3
GO:0043484	regulation of RNA splicing	7.416865e-3
GO:0071447	cellular response to hydroperoxide	7.560520e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	7.560520e-3
GO:0050702	interleukin-1 beta secretion	7.560520e-3
GO:0015911	plasma membrane long-chain fatty acid transport	7.560520e-3
GO:0030317	sperm motility	7.631185e-3
GO:0060083	smooth muscle contraction involved in micturition	7.693629e-3
GO:0003350	pulmonary myocardium development	7.693629e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	7.693629e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	7.726971e-3
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	7.735513e-3
GO:0002034	regulation of blood vessel size by renin-angiotensin	7.740235e-3
GO:0009411	response to UV	7.755879e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	7.776052e-3
GO:0048864	stem cell development	7.903160e-3
GO:0009083	branched chain family amino acid catabolic process	7.934654e-3
GO:0032423	regulation of mismatch repair	7.992286e-3
GO:0006559	L-phenylalanine catabolic process	7.992286e-3
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	8.010437e-3
GO:0032836	glomerular basement membrane development	8.010437e-3
GO:0035022	positive regulation of Rac protein signal transduction	8.010437e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	8.104574e-3
GO:0002076	osteoblast development	8.169560e-3
GO:0000041	transition metal ion transport	8.181318e-3
GO:0060525	prostate glandular acinus development	8.183949e-3
GO:0016192	vesicle-mediated transport	8.348162e-3
GO:0006376	mRNA splice site selection	8.375676e-3
GO:0035750	protein localization to myelin sheath abaxonal region	8.494663e-3
GO:0035105	sterol regulatory element binding protein import into nucleus	8.494663e-3
GO:0031161	phosphatidylinositol catabolic process	8.494663e-3