Novel motif:151

name:	motif151_GCCYGTGCMKCW

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0043088	regulation of Cdc42 GTPase activity	7.356144e-12
GO:0031442	positive regulation of mRNA 3'-end processing	5.502993e-10
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	7.018822e-10
GO:0060253	negative regulation of glial cell proliferation	9.012985e-10
GO:0060251	regulation of glial cell proliferation	9.650074e-10
GO:0043089	positive regulation of Cdc42 GTPase activity	3.054852e-9
GO:0002679	respiratory burst involved in defense response	3.751187e-9
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	7.354210e-9
GO:0045415	negative regulation of interleukin-8 biosynthetic process	1.420285e-8
GO:0043966	histone H3 acetylation	2.115038e-8
GO:0014014	negative regulation of gliogenesis	2.762719e-8
GO:0043585	nose morphogenesis	3.567033e-8
GO:0043487	regulation of RNA stability	4.519889e-8
GO:0019086	late viral mRNA transcription	7.210344e-8
GO:0010310	regulation of hydrogen peroxide metabolic process	7.465911e-8
GO:0043488	regulation of mRNA stability	7.563426e-8
GO:0071732	cellular response to nitric oxide	9.759904e-8
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	1.042450e-7
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1.115152e-7
GO:0031064	negative regulation of histone deacetylation	1.531957e-7
GO:0071816	tail-anchored membrane protein insertion into ER membrane	2.056336e-7
GO:0022011	myelination in peripheral nervous system	2.561329e-7
GO:0050685	positive regulation of mRNA processing	2.671867e-7
GO:0035499	carnosine biosynthetic process	2.694063e-7
GO:0010626	negative regulation of Schwann cell proliferation	2.936217e-7
GO:0045217	cell-cell junction maintenance	3.836901e-7
GO:0014037	Schwann cell differentiation	3.892858e-7
GO:0045064	T-helper 2 cell differentiation	3.990234e-7
GO:0002315	marginal zone B cell differentiation	3.990234e-7
GO:0010739	positive regulation of protein kinase A signaling cascade	4.356311e-7
GO:0002149	hypochlorous acid biosynthetic process	4.588061e-7
GO:0007296	vitellogenesis	4.836617e-7
GO:0061099	negative regulation of protein tyrosine kinase activity	5.408044e-7
GO:2000272	negative regulation of receptor activity	6.112789e-7
GO:0006304	DNA modification	8.287977e-7
GO:0048561	establishment of organ orientation	8.320569e-7
GO:0014044	Schwann cell development	8.474091e-7
GO:0035507	regulation of myosin-light-chain-phosphatase activity	9.300668e-7
GO:0014807	regulation of somitogenesis	1.277190e-6
GO:0008078	mesodermal cell migration	1.297358e-6
GO:0045414	regulation of interleukin-8 biosynthetic process	1.307797e-6
GO:0071956	cellular component maintenance at cellular level	1.328805e-6
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	1.627417e-6
GO:0032864	activation of Cdc42 GTPase activity	1.877820e-6
GO:0044258	intestinal lipid catabolic process	1.879604e-6
GO:0018350	protein esterification	1.879604e-6
GO:0015891	siderophore transport	1.879604e-6
GO:0006801	superoxide metabolic process	1.920231e-6
GO:0018205	peptidyl-lysine modification	1.975322e-6
GO:0001885	endothelial cell development	2.223831e-6
GO:0035814	negative regulation of renal sodium excretion	2.226170e-6
GO:0006853	carnitine shuttle	2.340425e-6
GO:0071731	response to nitric oxide	2.467657e-6
GO:0000089	mitotic metaphase	3.024666e-6
GO:0001886	endothelial cell morphogenesis	3.103620e-6
GO:0003100	regulation of systemic arterial blood pressure by endothelin	3.126749e-6
GO:0032096	negative regulation of response to food	3.314011e-6
GO:0061014	positive regulation of mRNA catabolic process	3.503012e-6
GO:0043543	protein acylation	4.051996e-6
GO:0009264	deoxyribonucleotide catabolic process	4.604827e-6
GO:0010624	regulation of Schwann cell proliferation	4.902528e-6
GO:0000956	nuclear-transcribed mRNA catabolic process	4.957060e-6
GO:2000467	positive regulation of glycogen (starch) synthase activity	5.481819e-6
GO:0072337	modified amino acid transport	5.658447e-6
GO:0006285	base-excision repair, AP site formation	5.772856e-6
GO:0032099	negative regulation of appetite	6.821943e-6
GO:0021528	commissural neuron differentiation in spinal cord	6.890538e-6
GO:0050779	RNA destabilization	6.930013e-6
GO:0032926	negative regulation of activin receptor signaling pathway	7.127066e-6
GO:0033209	tumor necrosis factor-mediated signaling pathway	7.127934e-6
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	9.165399e-6
GO:0006475	internal protein amino acid acetylation	9.350735e-6
GO:0042474	middle ear morphogenesis	9.489559e-6
GO:0097152	mesenchymal cell apoptosis	9.501187e-6
GO:2001037	positive regulation of tongue muscle cell differentiation	9.501187e-6
GO:0060982	coronary artery morphogenesis	9.501187e-6
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.018263e-5
GO:0032312	regulation of ARF GTPase activity	1.073130e-5
GO:0000093	mitotic telophase	1.181881e-5
GO:0007386	compartment pattern specification	1.253933e-5
GO:0061013	regulation of mRNA catabolic process	1.262394e-5
GO:2000974	negative regulation of pro-B cell differentiation	1.269193e-5
GO:0031284	positive regulation of guanylate cyclase activity	1.329796e-5
GO:0034214	protein hexamerization	1.368884e-5
GO:0045668	negative regulation of osteoblast differentiation	1.420962e-5
GO:0032383	regulation of intracellular cholesterol transport	1.475346e-5
GO:0097039	protein linear polyubiquitination	1.499739e-5
GO:0071472	cellular response to salt stress	1.520434e-5
GO:0033683	nucleotide-excision repair, DNA incision	1.656581e-5
GO:0007028	cytoplasm organization	1.676742e-5
GO:0009133	nucleoside diphosphate biosynthetic process	1.720619e-5
GO:0006707	cholesterol catabolic process	1.724492e-5
GO:0042274	ribosomal small subunit biogenesis	1.727243e-5
GO:0031848	protection from non-homologous end joining at telomere	1.792749e-5
GO:0045606	positive regulation of epidermal cell differentiation	1.897574e-5
GO:0015879	carnitine transport	1.928402e-5
GO:2000002	negative regulation of DNA damage checkpoint	2.030139e-5
GO:0070625	zymogen granule exocytosis	2.030139e-5
GO:0021551	central nervous system morphogenesis	2.030139e-5
GO:0021588	cerebellum formation	2.030139e-5
GO:0022004	midbrain-hindbrain boundary maturation during brain development	2.030139e-5
GO:0006473	protein acetylation	2.153716e-5
GO:0042093	T-helper cell differentiation	2.303564e-5
GO:0043313	regulation of neutrophil degranulation	2.353244e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	2.433171e-5
GO:0043921	modulation by host of viral transcription	2.574664e-5
GO:0016188	synaptic vesicle maturation	2.728168e-5
GO:0031330	negative regulation of cellular catabolic process	2.794645e-5
GO:0030046	parallel actin filament bundle assembly	2.843280e-5
GO:0018393	internal peptidyl-lysine acetylation	2.850242e-5
GO:0033687	osteoblast proliferation	3.085997e-5
GO:0006449	regulation of translational termination	3.128017e-5
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	3.240863e-5
GO:0010889	regulation of sequestering of triglyceride	3.252832e-5
GO:2000465	regulation of glycogen (starch) synthase activity	3.290319e-5
GO:0018394	peptidyl-lysine acetylation	3.482717e-5
GO:0007023	post-chaperonin tubulin folding pathway	3.504132e-5
GO:0042053	regulation of dopamine metabolic process	3.719477e-5
GO:0015887	pantothenate transmembrane transport	3.913218e-5
GO:0015878	biotin transport	3.913218e-5
GO:0032526	response to retinoic acid	4.015871e-5
GO:0046628	positive regulation of insulin receptor signaling pathway	4.654456e-5
GO:0016573	histone acetylation	4.654519e-5
GO:0034384	high-density lipoprotein particle clearance	4.706767e-5
GO:0021523	somatic motor neuron differentiation	4.706767e-5
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.739610e-5
GO:0042886	amide transport	5.445465e-5
GO:0030704	vitelline membrane formation	5.696067e-5
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	5.714836e-5
GO:0002115	store-operated calcium entry	5.717018e-5
GO:0009162	deoxyribonucleoside monophosphate metabolic process	5.721007e-5
GO:0071514	genetic imprinting	5.811651e-5
GO:0031440	regulation of mRNA 3'-end processing	6.011946e-5
GO:0045112	integrin biosynthetic process	6.037596e-5
GO:0001570	vasculogenesis	6.082472e-5
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	6.092614e-5
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	6.092614e-5
GO:0043353	enucleate erythrocyte differentiation	6.162942e-5
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	6.828398e-5
GO:0043314	negative regulation of neutrophil degranulation	7.337484e-5
GO:0051702	interaction with symbiont	7.631538e-5
GO:0015780	nucleotide-sugar transport	7.660177e-5
GO:0002268	follicular dendritic cell differentiation	8.134654e-5
GO:0032108	negative regulation of response to nutrient levels	8.653002e-5
GO:0051851	modification by host of symbiont morphology or physiology	9.519977e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	9.746328e-5
GO:0051645	Golgi localization	9.796846e-5
GO:0042069	regulation of catecholamine metabolic process	9.945281e-5
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.017531e-4
GO:0033233	regulation of protein sumoylation	1.110897e-4
GO:0045686	negative regulation of glial cell differentiation	1.124386e-4
GO:0090141	positive regulation of mitochondrial fission	1.149735e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.149735e-4
GO:2000077	negative regulation of type B pancreatic cell development	1.153233e-4
GO:0045007	depurination	1.153233e-4
GO:0032202	telomere assembly	1.185206e-4
GO:0032417	positive regulation of sodium:hydrogen antiporter activity	1.253529e-4
GO:0060711	labyrinthine layer development	1.331905e-4
GO:0043491	protein kinase B signaling cascade	1.365583e-4
GO:0034614	cellular response to reactive oxygen species	1.429714e-4
GO:0002536	respiratory burst involved in inflammatory response	1.432475e-4
GO:0006349	regulation of gene expression by genetic imprinting	1.443950e-4
GO:0060395	SMAD protein signal transduction	1.506626e-4
GO:0043923	positive regulation by host of viral transcription	1.542061e-4
GO:0045684	positive regulation of epidermis development	1.564851e-4
GO:0032012	regulation of ARF protein signal transduction	1.573360e-4
GO:0051668	localization within membrane	1.730188e-4
GO:0018022	peptidyl-lysine methylation	1.814794e-4
GO:0000305	response to oxygen radical	1.818337e-4
GO:0001892	embryonic placenta development	1.870558e-4
GO:0021986	habenula development	1.872074e-4
GO:0034389	lipid particle organization	1.950181e-4
GO:0051205	protein insertion into membrane	2.031538e-4
GO:0032226	positive regulation of synaptic transmission, dopaminergic	2.078052e-4
GO:0006402	mRNA catabolic process	2.134306e-4
GO:0060484	lung-associated mesenchyme development	2.162957e-4
GO:0043922	negative regulation by host of viral transcription	2.185382e-4
GO:0007006	mitochondrial membrane organization	2.255363e-4
GO:0070904	transepithelial L-ascorbic acid transport	2.303082e-4
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	2.328927e-4
GO:0070194	synaptonemal complex disassembly	2.328927e-4
GO:0044240	multicellular organismal lipid catabolic process	2.426480e-4
GO:0090342	regulation of cell aging	2.445626e-4
GO:0015969	guanosine tetraphosphate metabolic process	2.554155e-4
GO:0035803	egg coat formation	2.554155e-4
GO:0009438	methylglyoxal metabolic process	2.558982e-4
GO:0007020	microtubule nucleation	2.590828e-4
GO:0000387	spliceosomal snRNP assembly	2.595703e-4
GO:0046626	regulation of insulin receptor signaling pathway	2.627453e-4
GO:0046015	regulation of transcription by glucose	2.671325e-4
GO:0031669	cellular response to nutrient levels	2.780519e-4
GO:0018023	peptidyl-lysine trimethylation	2.835803e-4
GO:0022009	central nervous system vasculogenesis	2.905582e-4
GO:0032233	positive regulation of actin filament bundle assembly	2.906441e-4
GO:0034101	erythrocyte homeostasis	3.035873e-4
GO:0045082	positive regulation of interleukin-10 biosynthetic process	3.057730e-4
GO:0010452	histone H3-K36 methylation	3.057730e-4
GO:0009262	deoxyribonucleotide metabolic process	3.114667e-4
GO:0015781	pyrimidine nucleotide-sugar transport	3.140988e-4
GO:0046952	ketone body catabolic process	3.342933e-4
GO:0010871	negative regulation of receptor biosynthetic process	3.366009e-4
GO:0000072	M phase specific microtubule process	3.433801e-4
GO:0002886	regulation of myeloid leukocyte mediated immunity	3.434605e-4
GO:0070301	cellular response to hydrogen peroxide	3.442411e-4
GO:0019430	removal of superoxide radicals	3.623848e-4
GO:0016125	sterol metabolic process	3.726250e-4
GO:0015844	monoamine transport	3.784076e-4
GO:0032933	SREBP-mediated signaling pathway	3.965795e-4
GO:0031668	cellular response to extracellular stimulus	4.116042e-4
GO:0003374	dynamin polymerization involved in mitochondrial fission	4.154150e-4
GO:0090149	membrane fission involved in mitochondrial fission	4.154150e-4
GO:0072060	outer medullary collecting duct development	4.159470e-4
GO:0072061	inner medullary collecting duct development	4.159470e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	4.159470e-4
GO:0071496	cellular response to external stimulus	4.347811e-4
GO:0019087	transformation of host cell by virus	4.409060e-4
GO:0030218	erythrocyte differentiation	4.475120e-4
GO:0045074	regulation of interleukin-10 biosynthetic process	4.504170e-4
GO:0001990	regulation of systemic arterial blood pressure by hormone	4.582227e-4
GO:0048549	positive regulation of pinocytosis	4.682318e-4
GO:0072595	maintenance of protein localization to organelle	4.766673e-4
GO:0097029	mature dendritic cell differentiation	4.910953e-4
GO:0071872	cellular response to epinephrine stimulus	4.910953e-4
GO:0008089	anterograde axon cargo transport	4.957669e-4
GO:0014013	regulation of gliogenesis	5.005450e-4
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	5.058819e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	5.191778e-4
GO:0070875	positive regulation of glycogen metabolic process	5.201493e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	5.257851e-4
GO:0006401	RNA catabolic process	5.306244e-4
GO:0048845	venous blood vessel morphogenesis	5.350469e-4
GO:0008589	regulation of smoothened signaling pathway	5.543760e-4
GO:0010713	negative regulation of collagen metabolic process	5.920372e-4
GO:0034589	hydroxyproline transport	6.053876e-4
GO:0015826	threonine transport	6.053876e-4
GO:0018027	peptidyl-lysine dimethylation	6.133603e-4
GO:0018208	peptidyl-proline modification	6.209433e-4
GO:0070873	regulation of glycogen metabolic process	6.247426e-4
GO:0001798	positive regulation of type IIa hypersensitivity	6.270835e-4
GO:0071470	cellular response to osmotic stress	6.371320e-4
GO:0009098	leucine biosynthetic process	6.416560e-4
GO:0043181	vacuolar sequestering	6.416560e-4
GO:0006550	isoleucine catabolic process	6.416560e-4
GO:0005985	sucrose metabolic process	6.416560e-4
GO:0000023	maltose metabolic process	6.416560e-4
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	6.503032e-4
GO:0060621	negative regulation of cholesterol import	6.578260e-4
GO:0015670	carbon dioxide transport	6.578260e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	6.702329e-4
GO:0000413	protein peptidyl-prolyl isomerization	6.702704e-4
GO:0045618	positive regulation of keratinocyte differentiation	6.805349e-4
GO:0009265	2'-deoxyribonucleotide biosynthetic process	7.096145e-4
GO:0022411	cellular component disassembly	7.101533e-4
GO:0019083	viral transcription	7.300790e-4
GO:0071845	cellular component disassembly at cellular level	7.342963e-4
GO:0009650	UV protection	7.515716e-4
GO:0007063	regulation of sister chromatid cohesion	7.515716e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	7.569442e-4
GO:0061003	positive regulation of dendritic spine morphogenesis	7.627720e-4
GO:0032374	regulation of cholesterol transport	7.638236e-4
GO:0046902	regulation of mitochondrial membrane permeability	7.874511e-4
GO:0035088	establishment or maintenance of apical/basal cell polarity	8.164396e-4
GO:0043249	erythrocyte maturation	8.289353e-4
GO:0006386	termination of RNA polymerase III transcription	8.301793e-4
GO:0006385	transcription elongation from RNA polymerase III promoter	8.301793e-4
GO:0045218	zonula adherens maintenance	8.356242e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.398193e-4
GO:0045879	negative regulation of smoothened signaling pathway	8.589224e-4
GO:0043163	cell envelope organization	8.903386e-4
GO:2000251	positive regulation of actin cytoskeleton reorganization	8.903386e-4
GO:0060620	regulation of cholesterol import	9.037540e-4
GO:0032365	intracellular lipid transport	9.122125e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	9.134477e-4
GO:0006621	protein retention in ER lumen	9.378999e-4
GO:0010225	response to UV-C	9.378999e-4
GO:0071392	cellular response to estradiol stimulus	9.401722e-4
GO:0032205	negative regulation of telomere maintenance	9.436411e-4
GO:0035871	protein K11-linked deubiquitination	9.538002e-4
GO:0043418	homocysteine catabolic process	9.538002e-4
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	9.538002e-4
GO:0035378	carbon dioxide transmembrane transport	9.538002e-4
GO:0035377	transepithelial water transport	9.538002e-4
GO:0019343	cysteine biosynthetic process via cystathionine	9.538002e-4
GO:0019346	transsulfuration	9.538002e-4
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	9.538002e-4
GO:0006535	cysteine biosynthetic process from serine	9.538002e-4
GO:0002089	lens morphogenesis in camera-type eye	9.613726e-4
GO:0034198	cellular response to amino acid starvation	9.819075e-4
GO:0008203	cholesterol metabolic process	9.839541e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.000481e-3
GO:0035269	protein O-linked mannosylation	1.000481e-3
GO:0006083	acetate metabolic process	1.000481e-3
GO:0006335	DNA replication-dependent nucleosome assembly	1.000481e-3
GO:0019242	methylglyoxal biosynthetic process	1.000481e-3
GO:0015669	gas transport	1.011206e-3
GO:0006457	protein folding	1.032007e-3
GO:0042363	fat-soluble vitamin catabolic process	1.034423e-3
GO:0042074	cell migration involved in gastrulation	1.043756e-3
GO:0030490	maturation of SSU-rRNA	1.047830e-3
GO:0050881	musculoskeletal movement	1.049147e-3
GO:0007635	chemosensory behavior	1.051218e-3
GO:0071705	nitrogen compound transport	1.058354e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.058902e-3
GO:0000303	response to superoxide	1.059215e-3
GO:0070483	detection of hypoxia	1.073350e-3
GO:2000209	regulation of anoikis	1.075937e-3
GO:0019448	L-cysteine catabolic process	1.088992e-3
GO:0006244	pyrimidine nucleotide catabolic process	1.089676e-3
GO:0048261	negative regulation of receptor-mediated endocytosis	1.092598e-3
GO:0015695	organic cation transport	1.093261e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.107485e-3
GO:0018916	nitrobenzene metabolic process	1.107485e-3
GO:0070831	basement membrane assembly	1.107485e-3
GO:0046655	folic acid metabolic process	1.109021e-3
GO:0048710	regulation of astrocyte differentiation	1.129142e-3
GO:0060267	positive regulation of respiratory burst	1.140023e-3
GO:0060674	placenta blood vessel development	1.140358e-3
GO:0032897	negative regulation of viral transcription	1.168038e-3
GO:0060177	regulation of angiotensin metabolic process	1.178277e-3
GO:0035090	maintenance of apical/basal cell polarity	1.187099e-3
GO:0070345	negative regulation of fat cell proliferation	1.187099e-3
GO:0051323	metaphase	1.232213e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	1.233042e-3
GO:0032094	response to food	1.256618e-3
GO:0003148	outflow tract septum morphogenesis	1.270542e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.297820e-3
GO:0060713	labyrinthine layer morphogenesis	1.301898e-3
GO:0048255	mRNA stabilization	1.307578e-3
GO:0010890	positive regulation of sequestering of triglyceride	1.346766e-3
GO:0072110	glomerular mesangial cell proliferation	1.380020e-3
GO:0060038	cardiac muscle cell proliferation	1.474370e-3
GO:0031365	N-terminal protein amino acid modification	1.482542e-3
GO:0090239	regulation of histone H4 acetylation	1.512655e-3
GO:0010216	maintenance of DNA methylation	1.512655e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	1.529064e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.529574e-3
GO:0021512	spinal cord anterior/posterior patterning	1.529574e-3
GO:0015761	mannose transport	1.529574e-3
GO:0019413	acetate biosynthetic process	1.529574e-3
GO:0019542	propionate biosynthetic process	1.529574e-3
GO:0060708	spongiotrophoblast differentiation	1.582198e-3
GO:0007509	mesoderm migration involved in gastrulation	1.615641e-3
GO:0045109	intermediate filament organization	1.628820e-3
GO:0002335	mature B cell differentiation	1.645290e-3
GO:0030851	granulocyte differentiation	1.654327e-3
GO:2000300	regulation of synaptic vesicle exocytosis	1.662258e-3
GO:0009440	cyanate catabolic process	1.673698e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	1.688211e-3
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	1.688211e-3
GO:0032423	regulation of mismatch repair	1.704301e-3
GO:0034227	tRNA thio-modification	1.714773e-3
GO:0002098	tRNA wobble uridine modification	1.714773e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	1.719685e-3
GO:0045006	DNA deamination	1.748823e-3
GO:0042088	T-helper 1 type immune response	1.783401e-3
GO:0051965	positive regulation of synapse assembly	1.787345e-3
GO:0060669	embryonic placenta morphogenesis	1.815513e-3
GO:0006415	translational termination	1.827503e-3
GO:0009071	serine family amino acid catabolic process	1.847399e-3
GO:0060789	hair follicle placode formation	1.862034e-3
GO:0022027	interkinetic nuclear migration	1.862034e-3
GO:0031282	regulation of guanylate cyclase activity	1.889237e-3
GO:0000076	DNA replication checkpoint	1.920650e-3
GO:0019088	immortalization of host cell by virus	1.929124e-3
GO:0006231	dTMP biosynthetic process	1.929124e-3
GO:0008616	queuosine biosynthetic process	1.929124e-3
GO:0002002	regulation of angiotensin levels in blood	1.953283e-3
GO:0032329	serine transport	2.071513e-3
GO:0043467	regulation of generation of precursor metabolites and energy	2.085348e-3
GO:0006306	DNA methylation	2.086576e-3
GO:0060419	heart growth	2.132805e-3
GO:0042942	D-serine transport	2.136946e-3
GO:0043985	histone H4-R3 methylation	2.164961e-3
GO:0055017	cardiac muscle tissue growth	2.195518e-3
GO:0060977	coronary vasculature morphogenesis	2.217649e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.217649e-3
GO:0018105	peptidyl-serine phosphorylation	2.231498e-3
GO:0015788	UDP-N-acetylglucosamine transport	2.238859e-3
GO:0032862	activation of Rho GTPase activity	2.239155e-3
GO:0072526	pyridine-containing compound catabolic process	2.260804e-3
GO:0048711	positive regulation of astrocyte differentiation	2.292896e-3
GO:0060052	neurofilament cytoskeleton organization	2.310839e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	2.311327e-3
GO:0019730	antimicrobial humoral response	2.335999e-3
GO:0006991	response to sterol depletion	2.338671e-3
GO:0040030	regulation of molecular function, epigenetic	2.362939e-3
GO:0010469	regulation of receptor activity	2.474439e-3
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	2.482340e-3
GO:0072109	glomerular mesangium development	2.482541e-3
GO:0071356	cellular response to tumor necrosis factor	2.532176e-3
GO:0048339	paraxial mesoderm development	2.550448e-3
GO:2000737	negative regulation of stem cell differentiation	2.557662e-3
GO:0060707	trophoblast giant cell differentiation	2.564525e-3
GO:0032765	positive regulation of mast cell cytokine production	2.640497e-3
GO:0060242	contact inhibition	2.640497e-3
GO:0021644	vagus nerve morphogenesis	2.640497e-3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2.656101e-3
GO:0045725	positive regulation of glycogen biosynthetic process	2.715563e-3
GO:0090344	negative regulation of cell aging	2.728011e-3
GO:0005979	regulation of glycogen biosynthetic process	2.729495e-3
GO:0051567	histone H3-K9 methylation	2.752784e-3
GO:0090241	negative regulation of histone H4 acetylation	2.752784e-3
GO:0031953	negative regulation of protein autophosphorylation	2.784707e-3
GO:0001300	chronological cell aging	2.786673e-3
GO:0032682	negative regulation of chemokine production	2.815488e-3
GO:0097150	neuronal stem cell maintenance	2.852321e-3
GO:0043586	tongue development	2.854629e-3
GO:0035601	protein deacylation	2.871120e-3
GO:0033235	positive regulation of protein sumoylation	2.894219e-3
GO:0051414	response to cortisol stimulus	2.925184e-3
GO:0071476	cellular hypotonic response	2.948654e-3
GO:0046340	diacylglycerol catabolic process	2.948654e-3
GO:0032098	regulation of appetite	2.984485e-3
GO:0031670	cellular response to nutrient	3.035072e-3
GO:0016569	covalent chromatin modification	3.038706e-3
GO:0000244	assembly of spliceosomal tri-snRNP	3.049945e-3
GO:0006706	steroid catabolic process	3.069303e-3
GO:0034380	high-density lipoprotein particle assembly	3.094635e-3
GO:0090140	regulation of mitochondrial fission	3.134041e-3
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	3.138249e-3
GO:0045079	negative regulation of chemokine biosynthetic process	3.138249e-3
GO:0060216	definitive hemopoiesis	3.157033e-3
GO:0070327	thyroid hormone transport	3.170872e-3
GO:0042761	very long-chain fatty acid biosynthetic process	3.204954e-3
GO:0006476	protein deacetylation	3.226254e-3
GO:0006826	iron ion transport	3.250673e-3
GO:0045651	positive regulation of macrophage differentiation	3.252170e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	3.290090e-3
GO:0010544	negative regulation of platelet activation	3.304868e-3
GO:0060716	labyrinthine layer blood vessel development	3.365205e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	3.365251e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3.503904e-3
GO:0051958	methotrexate transport	3.503904e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	3.510910e-3
GO:0060872	semicircular canal development	3.517929e-3
GO:0021526	medial motor column neuron differentiation	3.521043e-3
GO:0002309	T cell proliferation involved in immune response	3.521043e-3
GO:0030823	regulation of cGMP metabolic process	3.536936e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	3.584565e-3
GO:0010608	posttranscriptional regulation of gene expression	3.584641e-3
GO:0045806	negative regulation of endocytosis	3.650162e-3
GO:0030157	pancreatic juice secretion	3.652762e-3
GO:0071477	cellular hypotonic salinity response	3.652885e-3
GO:0060456	positive regulation of digestive system process	3.656974e-3
GO:0018026	peptidyl-lysine monomethylation	3.687083e-3
GO:0031017	exocrine pancreas development	3.716192e-3
GO:0016570	histone modification	3.736498e-3
GO:0042491	auditory receptor cell differentiation	3.772067e-3
GO:0015696	ammonium transport	3.777329e-3
GO:0032008	positive regulation of TOR signaling cascade	3.789078e-3
GO:0071879	positive regulation of adrenergic receptor signaling pathway	3.875767e-3
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	3.875767e-3
GO:0006742	NADP catabolic process	3.875767e-3
GO:0010905	negative regulation of UDP-glucose catabolic process	3.875767e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	3.939468e-3
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	3.939468e-3
GO:0018293	protein-FAD linkage	3.939468e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	3.939468e-3
GO:0033700	phospholipid efflux	3.948105e-3
GO:0072668	tubulin complex biogenesis	4.020388e-3
GO:0045008	depyrimidination	4.028046e-3
GO:0048712	negative regulation of astrocyte differentiation	4.088558e-3
GO:0021903	rostrocaudal neural tube patterning	4.107337e-3
GO:0010891	negative regulation of sequestering of triglyceride	4.112729e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	4.116698e-3
GO:0032793	positive regulation of CREB transcription factor activity	4.134495e-3
GO:0043300	regulation of leukocyte degranulation	4.142130e-3
GO:0017187	peptidyl-glutamic acid carboxylation	4.192730e-3
GO:0090251	protein localization involved in establishment of planar polarity	4.213141e-3
GO:0060837	blood vessel endothelial cell differentiation	4.213141e-3
GO:0019402	galactitol metabolic process	4.213141e-3
GO:0060023	soft palate development	4.218544e-3
GO:0051457	maintenance of protein location in nucleus	4.248919e-3
GO:0009635	response to herbicide	4.313467e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	4.320282e-3
GO:0033146	regulation of estrogen receptor signaling pathway	4.333887e-3
GO:0033002	muscle cell proliferation	4.363811e-3
GO:0014898	cardiac muscle hypertrophy in response to stress	4.371381e-3
GO:0016575	histone deacetylation	4.433437e-3
GO:0072553	terminal button organization	4.434784e-3
GO:0060981	cell migration involved in coronary angiogenesis	4.434784e-3
GO:0071670	smooth muscle cell chemotaxis	4.434784e-3
GO:0002522	leukocyte migration involved in immune response	4.434784e-3
GO:0000088	mitotic prophase	4.434784e-3
GO:0035623	renal glucose absorption	4.434784e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	4.442300e-3
GO:0072488	ammonium transmembrane transport	4.442300e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	4.442300e-3
GO:0051684	maintenance of Golgi location	4.506300e-3
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	4.506300e-3
GO:0090321	positive regulation of chylomicron remnant clearance	4.506300e-3
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	4.506300e-3
GO:0010509	polyamine homeostasis	4.506300e-3
GO:0032738	positive regulation of interleukin-15 production	4.506300e-3
GO:0032853	positive regulation of Ran GTPase activity	4.506300e-3
GO:0003300	cardiac muscle hypertrophy	4.576314e-3
GO:0001302	replicative cell aging	4.655059e-3
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	4.693181e-3
GO:2000297	negative regulation of synapse maturation	4.693181e-3
GO:0050872	white fat cell differentiation	4.693429e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010900	negative regulation of phosphatidylcholine catabolic process	2.661097e-9
GO:0034447	very-low-density lipoprotein particle clearance	2.290557e-7
GO:0031558	induction of apoptosis in response to chemical stimulus	2.635961e-7
GO:0048305	immunoglobulin secretion	4.529390e-7
GO:0031442	positive regulation of mRNA 3'-end processing	7.090050e-7
GO:0061028	establishment of endothelial barrier	2.109206e-6
GO:0014045	establishment of endothelial blood-brain barrier	2.911851e-6
GO:0050685	positive regulation of mRNA processing	5.710661e-6
GO:0051583	dopamine uptake	6.697780e-6
GO:0031440	regulation of mRNA 3'-end processing	7.296857e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	9.729041e-6
GO:0045922	negative regulation of fatty acid metabolic process	1.138656e-5
GO:0033239	negative regulation of cellular amine metabolic process	1.618344e-5
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.805479e-5
GO:0006654	phosphatidic acid biosynthetic process	2.126386e-5
GO:0019285	glycine betaine biosynthetic process from choline	3.421116e-5
GO:0048535	lymph node development	3.546939e-5
GO:0022009	central nervous system vasculogenesis	3.696797e-5
GO:0018193	peptidyl-amino acid modification	3.895113e-5
GO:2001037	positive regulation of tongue muscle cell differentiation	4.287873e-5
GO:0010424	DNA methylation on cytosine within a CG sequence	4.565470e-5
GO:0018230	peptidyl-L-cysteine S-palmitoylation	4.770877e-5
GO:0010155	regulation of proton transport	4.778101e-5
GO:0000578	embryonic axis specification	5.213550e-5
GO:0042398	cellular modified amino acid biosynthetic process	5.364625e-5
GO:0001885	endothelial cell development	6.612739e-5
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	6.615998e-5
GO:0018293	protein-FAD linkage	6.615998e-5
GO:0001579	medium-chain fatty acid transport	6.615998e-5
GO:0006611	protein export from nucleus	7.314656e-5
GO:0001777	T cell homeostatic proliferation	7.346620e-5
GO:0034214	protein hexamerization	7.567434e-5
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	8.413085e-5
GO:0070286	axonemal dynein complex assembly	8.413085e-5
GO:0002407	dendritic cell chemotaxis	9.482101e-5
GO:0060896	neural plate pattern specification	9.868546e-5
GO:0090234	regulation of kinetochore assembly	9.998512e-5
GO:0090169	regulation of spindle assembly	9.998512e-5
GO:0031848	protection from non-homologous end joining at telomere	1.060981e-4
GO:0002352	B cell negative selection	1.097534e-4
GO:0061014	positive regulation of mRNA catabolic process	1.152837e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	1.405832e-4
GO:0010891	negative regulation of sequestering of triglyceride	1.455860e-4
GO:0001963	synaptic transmission, dopaminergic	1.626053e-4
GO:0032776	DNA methylation on cytosine	1.668467e-4
GO:0070316	regulation of G0 to G1 transition	1.859995e-4
GO:0001570	vasculogenesis	2.066668e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	2.080792e-4
GO:2000781	positive regulation of double-strand break repair	2.203187e-4
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.203187e-4
GO:0072610	interleukin-12 secretion	2.488309e-4
GO:0097022	lymphocyte migration into lymph node	2.488309e-4
GO:0034441	plasma lipoprotein particle oxidation	2.488309e-4
GO:0002077	acrosome matrix dispersal	2.489881e-4
GO:0034393	positive regulation of smooth muscle cell apoptosis	2.544649e-4
GO:0034983	peptidyl-lysine deacetylation	2.638117e-4
GO:0071242	cellular response to ammonium ion	2.721281e-4
GO:0018105	peptidyl-serine phosphorylation	2.780428e-4
GO:0046849	bone remodeling	2.943084e-4
GO:0045920	negative regulation of exocytosis	3.231981e-4
GO:0032239	regulation of nucleobase-containing compound transport	3.526937e-4
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	3.526937e-4
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	3.526937e-4
GO:0070232	regulation of T cell apoptosis	3.569318e-4
GO:0051341	regulation of oxidoreductase activity	3.611115e-4
GO:0060696	regulation of phospholipid catabolic process	3.698126e-4
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.813766e-4
GO:0043301	negative regulation of leukocyte degranulation	4.047987e-4
GO:0051168	nuclear export	4.311635e-4
GO:0002268	follicular dendritic cell differentiation	4.553901e-4
GO:0051204	protein insertion into mitochondrial membrane	4.601453e-4
GO:0043587	tongue morphogenesis	4.682993e-4
GO:0006513	protein monoubiquitination	4.961587e-4
GO:0097026	dendritic cell dendrite assembly	5.164549e-4
GO:0043314	negative regulation of neutrophil degranulation	5.275704e-4
GO:0085020	protein K6-linked ubiquitination	5.412185e-4
GO:0018209	peptidyl-serine modification	5.792113e-4
GO:0033523	histone H2B ubiquitination	5.874906e-4
GO:0051865	protein autoubiquitination	5.885391e-4
GO:0045446	endothelial cell differentiation	5.956307e-4
GO:0021999	neural plate anterior/posterior regionalization	6.011333e-4
GO:0003158	endothelium development	6.022585e-4
GO:0035725	sodium ion transmembrane transport	6.311857e-4
GO:0002897	positive regulation of central B cell tolerance induction	6.579900e-4
GO:0002508	central tolerance induction	6.579900e-4
GO:0033590	response to cobalamin	6.628096e-4
GO:0002635	negative regulation of germinal center formation	6.628096e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	6.706325e-4
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	6.788472e-4
GO:0097107	postsynaptic density assembly	6.788472e-4
GO:0045585	positive regulation of cytotoxic T cell differentiation	6.788472e-4
GO:0046604	positive regulation of mitotic centrosome separation	7.336667e-4
GO:0021528	commissural neuron differentiation in spinal cord	7.336667e-4
GO:0035234	germ cell programmed cell death	7.659839e-4
GO:0051084	'de novo' posttranslational protein folding	7.821171e-4
GO:0051135	positive regulation of NK T cell activation	7.845519e-4
GO:0006346	methylation-dependent chromatin silencing	7.851798e-4
GO:0090083	regulation of inclusion body assembly	7.851798e-4
GO:0070542	response to fatty acid	8.597188e-4
GO:0072061	inner medullary collecting duct development	8.614367e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	8.614367e-4
GO:0072060	outer medullary collecting duct development	8.614367e-4
GO:0071870	cellular response to catecholamine stimulus	9.074814e-4
GO:0021533	cell differentiation in hindbrain	9.569133e-4
GO:0043951	negative regulation of cAMP-mediated signaling	9.950235e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	9.950235e-4
GO:0016539	intein-mediated protein splicing	9.950235e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	9.950235e-4
GO:0042149	cellular response to glucose starvation	1.029661e-3
GO:0006099	tricarboxylic acid cycle	1.035341e-3
GO:0016242	negative regulation of macroautophagy	1.089774e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.113296e-3
GO:0060897	neural plate regionalization	1.122141e-3
GO:0015851	nucleobase transport	1.122141e-3
GO:0009880	embryonic pattern specification	1.150335e-3
GO:0072074	kidney mesenchyme development	1.213369e-3
GO:0009199	ribonucleoside triphosphate metabolic process	1.221327e-3
GO:0030917	midbrain-hindbrain boundary development	1.227795e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.288842e-3
GO:0021587	cerebellum morphogenesis	1.293494e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.299430e-3
GO:0006844	acyl carnitine transport	1.299430e-3
GO:0060299	negative regulation of sarcomere organization	1.299430e-3
GO:0046330	positive regulation of JNK cascade	1.357462e-3
GO:0033085	negative regulation of T cell differentiation in thymus	1.368707e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.384502e-3
GO:0090026	positive regulation of monocyte chemotaxis	1.385576e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	1.444173e-3
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	1.444173e-3
GO:0015844	monoamine transport	1.453669e-3
GO:0006658	phosphatidylserine metabolic process	1.477623e-3
GO:0006808	regulation of nitrogen utilization	1.497267e-3
GO:0060674	placenta blood vessel development	1.514272e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	1.559663e-3
GO:0043313	regulation of neutrophil degranulation	1.578860e-3
GO:0008589	regulation of smoothened signaling pathway	1.592005e-3
GO:0070368	positive regulation of hepatocyte differentiation	1.602608e-3
GO:0010661	positive regulation of muscle cell apoptosis	1.615782e-3
GO:0046847	filopodium assembly	1.641597e-3
GO:0045792	negative regulation of cell size	1.676583e-3
GO:0090045	positive regulation of deacetylase activity	1.680495e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.680495e-3
GO:0046602	regulation of mitotic centrosome separation	1.705699e-3
GO:0019264	glycine biosynthetic process from serine	1.705699e-3
GO:0061077	chaperone-mediated protein folding	1.713848e-3
GO:0072205	metanephric collecting duct development	1.759186e-3
GO:0016241	regulation of macroautophagy	1.795059e-3
GO:0010833	telomere maintenance via telomere lengthening	1.795059e-3
GO:0009109	coenzyme catabolic process	1.808925e-3
GO:0043543	protein acylation	1.865292e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	1.882760e-3
GO:0051590	positive regulation of neurotransmitter transport	1.908949e-3
GO:0051573	negative regulation of histone H3-K9 methylation	1.954547e-3
GO:0050779	RNA destabilization	1.954547e-3
GO:0010887	negative regulation of cholesterol storage	1.985972e-3
GO:0033004	negative regulation of mast cell activation	2.049721e-3
GO:0032855	positive regulation of Rac GTPase activity	2.087642e-3
GO:0045880	positive regulation of smoothened signaling pathway	2.105972e-3
GO:0046341	CDP-diacylglycerol metabolic process	2.110232e-3
GO:0015684	ferrous iron transport	2.150545e-3
GO:0006405	RNA export from nucleus	2.207542e-3
GO:0050718	positive regulation of interleukin-1 beta secretion	2.293723e-3
GO:0018210	peptidyl-threonine modification	2.352101e-3
GO:0002649	regulation of tolerance induction to self antigen	2.405004e-3
GO:0048239	negative regulation of DNA recombination at telomere	2.443079e-3
GO:0046670	positive regulation of retinal cell programmed cell death	2.443079e-3
GO:0033617	mitochondrial respiratory chain complex IV assembly	2.443079e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	2.443079e-3
GO:0006430	lysyl-tRNA aminoacylation	2.443079e-3
GO:0030035	microspike assembly	2.577200e-3
GO:0072075	metanephric mesenchyme development	2.699919e-3
GO:0009146	purine nucleoside triphosphate catabolic process	2.751229e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	2.755317e-3
GO:0051580	regulation of neurotransmitter uptake	2.761184e-3
GO:0006406	mRNA export from nucleus	2.839837e-3
GO:0051984	positive regulation of chromosome segregation	2.850069e-3
GO:0006184	GTP catabolic process	2.921246e-3
GO:0009144	purine nucleoside triphosphate metabolic process	2.935318e-3
GO:0045879	negative regulation of smoothened signaling pathway	2.952860e-3
GO:0090399	replicative senescence	2.978266e-3
GO:0061205	paramesonephric duct development	2.981500e-3
GO:0045184	establishment of protein localization	3.074580e-3
GO:2000744	positive regulation of anterior head development	3.076814e-3
GO:0045905	positive regulation of translational termination	3.076814e-3
GO:0006452	translational frameshifting	3.076814e-3
GO:0045901	positive regulation of translational elongation	3.076814e-3
GO:0032933	SREBP-mediated signaling pathway	3.194845e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	3.264894e-3
GO:0007144	female meiosis I	3.264894e-3
GO:0016575	histone deacetylation	3.278841e-3
GO:0002339	B cell selection	3.332321e-3
GO:0001977	renal system process involved in regulation of blood volume	3.358126e-3
GO:0051323	metaphase	3.385224e-3
GO:0070243	regulation of thymocyte apoptosis	3.522156e-3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3.600583e-3
GO:0045660	positive regulation of neutrophil differentiation	3.600583e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	3.600583e-3
GO:0070318	positive regulation of G0 to G1 transition	3.671524e-3
GO:0009107	lipoate biosynthetic process	3.683791e-3
GO:0045210	FasL biosynthetic process	3.683791e-3
GO:0006526	arginine biosynthetic process	3.683791e-3
GO:0060385	axonogenesis involved in innervation	3.813755e-3
GO:0009143	nucleoside triphosphate catabolic process	3.862083e-3
GO:0035640	exploration behavior	3.925205e-3
GO:0006837	serotonin transport	3.953830e-3
GO:0014015	positive regulation of gliogenesis	4.032675e-3
GO:2000543	positive regulation of gastrulation	4.033346e-3
GO:0045175	basal protein localization	4.063044e-3
GO:2000412	positive regulation of thymocyte migration	4.152397e-3
GO:0002518	lymphocyte chemotaxis across high endothelial venule	4.152397e-3
GO:0006449	regulation of translational termination	4.152397e-3
GO:0015670	carbon dioxide transport	4.288765e-3
GO:2000779	regulation of double-strand break repair	4.305792e-3
GO:0032768	regulation of monooxygenase activity	4.318292e-3
GO:0015724	formate transport	4.319670e-3
GO:0015876	acetyl-CoA transport	4.319670e-3
GO:0061302	smooth muscle cell-matrix adhesion	4.322386e-3
GO:0000053	argininosuccinate metabolic process	4.322386e-3
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	4.354763e-3
GO:0015780	nucleotide-sugar transport	4.354763e-3
GO:0046958	nonassociative learning	4.370851e-3
GO:0006668	sphinganine-1-phosphate metabolic process	4.370851e-3
GO:0043949	regulation of cAMP-mediated signaling	4.383420e-3
GO:0015872	dopamine transport	4.548746e-3
GO:0009141	nucleoside triphosphate metabolic process	4.572476e-3
GO:0010721	negative regulation of cell development	4.633522e-3
GO:0032094	response to food	4.677945e-3
GO:0048368	lateral mesoderm development	4.680827e-3
GO:0006863	purine base transport	4.680827e-3
GO:0001909	leukocyte mediated cytotoxicity	4.707662e-3
GO:0060026	convergent extension	4.826295e-3
GO:0006413	translational initiation	4.895267e-3
GO:0030835	negative regulation of actin filament depolymerization	4.971590e-3
GO:0043503	skeletal muscle fiber adaptation	4.975495e-3
GO:0051588	regulation of neurotransmitter transport	4.985242e-3
GO:0060458	right lung development	5.014516e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	5.014516e-3
GO:0019348	dolichol metabolic process	5.014516e-3
GO:0002036	regulation of L-glutamate transport	5.014516e-3
GO:0045602	negative regulation of endothelial cell differentiation	5.014516e-3
GO:0051354	negative regulation of oxidoreductase activity	5.028848e-3
GO:0032967	positive regulation of collagen biosynthetic process	5.028848e-3
GO:0060439	trachea morphogenesis	5.057367e-3
GO:0010464	regulation of mesenchymal cell proliferation	5.132800e-3
GO:0046831	regulation of RNA export from nucleus	5.186436e-3
GO:0072488	ammonium transmembrane transport	5.208980e-3
GO:0018345	protein palmitoylation	5.251101e-3
GO:0051353	positive regulation of oxidoreductase activity	5.280607e-3
GO:0016567	protein ubiquitination	5.292740e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	5.301335e-3
GO:0060837	blood vessel endothelial cell differentiation	5.338066e-3
GO:0032321	positive regulation of Rho GTPase activity	5.391006e-3
GO:0001840	neural plate development	5.393652e-3
GO:0050768	negative regulation of neurogenesis	5.403102e-3
GO:0010889	regulation of sequestering of triglyceride	5.475156e-3
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	5.540818e-3
GO:0006282	regulation of DNA repair	5.637680e-3
GO:0046590	embryonic leg morphogenesis	5.669607e-3
GO:0033158	regulation of protein import into nucleus, translocation	5.734087e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	5.845391e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	5.845391e-3
GO:0007257	activation of JUN kinase activity	5.950168e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	6.038717e-3
GO:0070932	histone H3 deacetylation	6.055104e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	6.055104e-3
GO:0035444	nickel ion transmembrane transport	6.055104e-3
GO:0032769	negative regulation of monooxygenase activity	6.060253e-3
GO:0090141	positive regulation of mitochondrial fission	6.126028e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	6.126028e-3
GO:0001556	oocyte maturation	6.215469e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	6.332357e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	6.332357e-3
GO:0045217	cell-cell junction maintenance	6.423296e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	6.440227e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	6.440227e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	6.440227e-3
GO:0018205	peptidyl-lysine modification	6.730757e-3
GO:0048793	pronephros development	6.772985e-3
GO:0060712	spongiotrophoblast layer development	6.772985e-3
GO:0009261	ribonucleotide catabolic process	6.775623e-3
GO:0070245	positive regulation of thymocyte apoptosis	6.780360e-3
GO:0006687	glycosphingolipid metabolic process	6.791768e-3
GO:0070234	positive regulation of T cell apoptosis	6.943412e-3
GO:0021575	hindbrain morphogenesis	6.978715e-3
GO:0032847	regulation of cellular pH reduction	6.993843e-3
GO:0010869	regulation of receptor biosynthetic process	7.037549e-3
GO:0043491	protein kinase B signaling cascade	7.092265e-3
GO:0015074	DNA integration	7.165297e-3
GO:0006577	betaine metabolic process	7.165297e-3
GO:0051030	snRNA transport	7.188121e-3
GO:0006998	nuclear envelope organization	7.228431e-3
GO:0046039	GTP metabolic process	7.274178e-3
GO:0021997	neural plate axis specification	7.309656e-3
GO:0016559	peroxisome fission	7.309656e-3
GO:0000089	mitotic metaphase	7.309656e-3
GO:0006551	leucine metabolic process	7.309656e-3
GO:0032849	positive regulation of cellular pH reduction	7.335210e-3
GO:0060716	labyrinthine layer blood vessel development	7.392849e-3
GO:0046356	acetyl-CoA catabolic process	7.557398e-3
GO:0072054	renal outer medulla development	7.705628e-3
GO:2000015	regulation of determination of dorsal identity	7.705628e-3
GO:0006705	mineralocorticoid biosynthetic process	7.705628e-3
GO:0006370	mRNA capping	7.705628e-3
GO:0044091	membrane biogenesis	7.705628e-3
GO:0006657	CDP-choline pathway	7.735944e-3
GO:0001768	establishment of T cell polarity	7.735944e-3
GO:0006663	platelet activating factor biosynthetic process	7.830529e-3
GO:2000426	negative regulation of apoptotic cell clearance	7.908119e-3
GO:0070585	protein localization in mitochondrion	7.990445e-3
GO:0005981	regulation of glycogen catabolic process	8.128393e-3
GO:0070317	negative regulation of G0 to G1 transition	8.135185e-3
GO:0080164	regulation of nitric oxide metabolic process	8.135185e-3
GO:0045234	protein palmitoleylation	8.135185e-3
GO:0035502	metanephric ureteric bud development	8.135185e-3
GO:0009443	pyridoxal 5'-phosphate salvage	8.135185e-3
GO:0034474	U2 snRNA 3'-end processing	8.135185e-3
GO:0006948	induction by virus of host cell-cell fusion	8.135185e-3
GO:0015031	protein transport	8.294855e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	8.351632e-3
GO:0018364	peptidyl-glutamine methylation	8.351632e-3
GO:0016191	synaptic vesicle uncoating	8.351632e-3
GO:0044246	regulation of multicellular organismal metabolic process	8.497181e-3
GO:0033037	polysaccharide localization	8.517657e-3
GO:0021681	cerebellar granular layer development	8.556370e-3
GO:0021548	pons development	8.605189e-3
GO:0009306	protein secretion	8.610814e-3
GO:0033036	macromolecule localization	8.615438e-3
GO:0051586	positive regulation of dopamine uptake	8.819318e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	8.918100e-3
GO:0002663	positive regulation of B cell tolerance induction	8.918100e-3
GO:0021702	cerebellar Purkinje cell differentiation	8.918494e-3
GO:0048477	oogenesis	8.942713e-3
GO:0060534	trachea cartilage development	9.057797e-3
GO:0009154	purine ribonucleotide catabolic process	9.063432e-3
GO:0046605	regulation of centrosome cycle	9.236622e-3
GO:0060017	parathyroid gland development	9.319255e-3
GO:0051823	regulation of synapse structural plasticity	9.319255e-3
GO:0090224	regulation of spindle organization	9.321390e-3
GO:0051584	regulation of dopamine uptake	9.321390e-3
GO:0002053	positive regulation of mesenchymal cell proliferation	9.365837e-3
GO:0072203	cell proliferation involved in metanephros development	9.372694e-3
GO:0010524	positive regulation of calcium ion transport into cytosol	9.536013e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	9.555759e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	9.555759e-3
GO:0006713	glucocorticoid catabolic process	9.555759e-3
GO:0022417	protein maturation by protein folding	9.555759e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	9.555759e-3
GO:0032277	negative regulation of gonadotropin secretion	9.641936e-3
GO:0018094	protein polyglycylation	9.641936e-3
GO:0051187	cofactor catabolic process	1.007678e-2
GO:0032862	activation of Rho GTPase activity	1.040339e-2
GO:0030100	regulation of endocytosis	1.042617e-2
GO:0002432	granuloma formation	1.063047e-2
GO:0090140	regulation of mitochondrial fission	1.063047e-2
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.063047e-2
GO:0071502	cellular response to temperature stimulus	1.065948e-2
GO:0097152	mesenchymal cell apoptosis	1.065948e-2
GO:0042664	negative regulation of endodermal cell fate specification	1.065948e-2
GO:0071104	response to interleukin-9	1.065948e-2
GO:0002380	immunoglobulin secretion involved in immune response	1.065948e-2
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	1.065948e-2
GO:0003273	cell migration involved in endocardial cushion formation	1.065948e-2
GO:0014827	intestine smooth muscle contraction	1.065948e-2
GO:0043547	positive regulation of GTPase activity	1.069904e-2
GO:0018108	peptidyl-tyrosine phosphorylation	1.083486e-2
GO:0034276	kynurenic acid biosynthetic process	1.099014e-2
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	1.099014e-2
GO:0019556	histidine catabolic process to glutamate and formamide	1.099014e-2
GO:0060975	cardioblast migration to the midline involved in heart field formation	1.099014e-2
GO:0002534	cytokine production involved in inflammatory response	1.099014e-2
GO:0003259	cardioblast anterior-lateral migration	1.099014e-2
GO:0003210	cardiac atrium formation	1.099014e-2
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.099014e-2
GO:0003236	sinus venosus morphogenesis	1.099014e-2
GO:0018107	peptidyl-threonine phosphorylation	1.132324e-2
GO:0070846	Hsp90 deacetylation	1.135673e-2
GO:0090042	tubulin deacetylation	1.135673e-2
GO:0034162	toll-like receptor 9 signaling pathway	1.135673e-2
GO:0032782	bile acid secretion	1.135673e-2
GO:0034138	toll-like receptor 3 signaling pathway	1.135673e-2
GO:0003096	renal sodium ion transport	1.135673e-2
GO:0015747	urate transport	1.144890e-2
GO:0008612	peptidyl-lysine modification to hypusine	1.144890e-2
GO:0071872	cellular response to epinephrine stimulus	1.160927e-2
GO:0070842	aggresome assembly	1.160927e-2
GO:0002579	positive regulation of antigen processing and presentation	1.173040e-2
GO:0018076	N-terminal peptidyl-lysine acetylation	1.177138e-2
GO:0070233	negative regulation of T cell apoptosis	1.192704e-2
GO:0033235	positive regulation of protein sumoylation	1.214177e-2
GO:0035434	copper ion transmembrane transport	1.214177e-2
GO:0060177	regulation of angiotensin metabolic process	1.229003e-2
GO:0046322	negative regulation of fatty acid oxidation	1.243217e-2
GO:0061013	regulation of mRNA catabolic process	1.262599e-2
GO:0008354	germ cell migration	1.271276e-2
GO:0051693	actin filament capping	1.273729e-2
GO:0046320	regulation of fatty acid oxidation	1.274090e-2
GO:0060286	flagellar cell motility	1.279273e-2
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	1.279273e-2
GO:0071422	succinate transmembrane transport	1.279273e-2
GO:0070256	negative regulation of mucus secretion	1.279273e-2
GO:0006601	creatine biosynthetic process	1.279273e-2
GO:0006994	positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	1.279273e-2
GO:0015891	siderophore transport	1.279273e-2
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	1.279273e-2
GO:0003093	regulation of glomerular filtration	1.302178e-2
GO:0072044	collecting duct development	1.311787e-2
GO:0006694	steroid biosynthetic process	1.336744e-2
GO:0045995	regulation of embryonic development	1.343036e-2
GO:0048260	positive regulation of receptor-mediated endocytosis	1.355984e-2
GO:2000425	regulation of apoptotic cell clearance	1.368502e-2
GO:0014056	regulation of acetylcholine secretion	1.368502e-2
GO:0051261	protein depolymerization	1.368502e-2
GO:0042396	phosphagen biosynthetic process	1.398254e-2
GO:0090116	C-5 methylation of cytosine	1.398254e-2
GO:0035166	post-embryonic hemopoiesis	1.398254e-2
GO:0019058	viral infectious cycle	1.404975e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.415748e-2
GO:0001881	receptor recycling	1.415748e-2
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.415748e-2
GO:0043300	regulation of leukocyte degranulation	1.424075e-2
GO:0032353	negative regulation of hormone biosynthetic process	1.426324e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.431633e-2
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.439236e-2
GO:0007509	mesoderm migration involved in gastrulation	1.459647e-2
GO:0030834	regulation of actin filament depolymerization	1.482856e-2
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.486061e-2
GO:0061034	olfactory bulb mitral cell layer development	1.494363e-2
GO:0071436	sodium ion export	1.494363e-2
GO:0006288	base-excision repair, DNA ligation	1.494363e-2
GO:0006344	maintenance of chromatin silencing	1.494363e-2
GO:0060466	activation of meiosis involved in egg activation	1.502990e-2
GO:0006030	chitin metabolic process	1.502990e-2
GO:0019722	calcium-mediated signaling	1.507700e-2
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	1.535339e-2
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	1.535339e-2
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	1.535339e-2
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	1.535339e-2
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	1.535339e-2
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	1.535339e-2
GO:0006437	tyrosyl-tRNA aminoacylation	1.535339e-2
GO:0030421	defecation	1.535339e-2
GO:0010625	positive regulation of Schwann cell proliferation	1.535339e-2
GO:0034635	glutathione transport	1.535339e-2
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	1.535339e-2
GO:0090007	regulation of mitotic anaphase	1.535339e-2
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.535339e-2
GO:0015696	ammonium transport	1.545355e-2
GO:0016090	prenol metabolic process	1.561303e-2
GO:0009798	axis specification	1.576356e-2
GO:0006284	base-excision repair	1.597048e-2
GO:0072111	cell proliferation involved in kidney development	1.604129e-2
GO:0021697	cerebellar cortex formation	1.606045e-2
GO:0045078	positive regulation of interferon-gamma biosynthetic process	1.619261e-2
GO:0070634	transepithelial ammonium transport	1.631916e-2
GO:0007288	sperm axoneme assembly	1.631916e-2
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	1.631916e-2
GO:0009150	purine ribonucleotide metabolic process	1.650005e-2
GO:0016458	gene silencing	1.678320e-2
GO:0043089	positive regulation of Cdc42 GTPase activity	1.701595e-2
GO:0018243	protein O-linked glycosylation via threonine	1.728430e-2
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.728430e-2
GO:0018242	protein O-linked glycosylation via serine	1.728430e-2
GO:0018065	protein-cofactor linkage	1.728430e-2
GO:0009166	nucleotide catabolic process	1.734116e-2
GO:0043968	histone H2A acetylation	1.744020e-2
GO:0072172	mesonephric tubule formation	1.750774e-2
GO:0035089	establishment of apical/basal cell polarity	1.750774e-2
GO:0071874	cellular response to norepinephrine stimulus	1.754952e-2
GO:0031999	negative regulation of fatty acid beta-oxidation	1.762627e-2
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.762627e-2
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	1.762627e-2
GO:0040019	positive regulation of embryonic development	1.815229e-2
GO:0072171	mesonephric tubule morphogenesis	1.819747e-2
GO:0034551	mitochondrial respiratory chain complex III assembly	1.834410e-2
GO:0060709	glycogen cell development involved in embryonic placenta development	1.834410e-2
GO:0035752	lysosomal lumen pH elevation	1.834410e-2
GO:0008611	ether lipid biosynthetic process	1.834410e-2
GO:0032342	aldosterone biosynthetic process	1.834410e-2
GO:0000046	autophagic vacuole fusion	1.834410e-2
GO:0001575	globoside metabolic process	1.834410e-2
GO:0042267	natural killer cell mediated cytotoxicity	1.879717e-2
GO:0002643	regulation of tolerance induction	1.950622e-2
GO:0008078	mesodermal cell migration	1.968127e-2
GO:0070366	regulation of hepatocyte differentiation	1.969963e-2
GO:0060433	bronchus development	1.989908e-2
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	2.000365e-2
GO:0007017	microtubule-based process	2.010731e-2
GO:0090002	establishment of protein localization in plasma membrane	2.014750e-2
GO:0045819	positive regulation of glycogen catabolic process	2.014750e-2
GO:0006359	regulation of transcription from RNA polymerase III promoter	2.074628e-2
GO:0006195	purine nucleotide catabolic process	2.093139e-2
GO:0045218	zonula adherens maintenance	2.095420e-2
GO:0048599	oocyte development	2.112307e-2
GO:0048842	positive regulation of axon extension involved in axon guidance	2.112611e-2
GO:0060988	lipid tube assembly	2.112611e-2
GO:0006669	sphinganine-1-phosphate biosynthetic process	2.112611e-2
GO:0072655	establishment of protein localization in mitochondrion	2.122506e-2
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.144624e-2
GO:0021547	midbrain-hindbrain boundary initiation	2.162783e-2
GO:0021754	facial nucleus development	2.162783e-2