Novel motif:158

name:	motif158_SRCGWYACA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0007586	digestion	1.430736e-20
GO:0022600	digestive system process	9.007673e-16
GO:0030277	maintenance of gastrointestinal epithelium	1.038167e-15
GO:0006955	immune response	3.801250e-14
GO:0002682	regulation of immune system process	1.099963e-13
GO:0002684	positive regulation of immune system process	1.770712e-13
GO:0050776	regulation of immune response	7.572308e-13
GO:0007166	cell surface receptor linked signaling pathway	2.799210e-12
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	3.481990e-12
GO:0045576	mast cell activation	1.526097e-11
GO:0071732	cellular response to nitric oxide	1.536546e-11
GO:0002376	immune system process	1.952498e-11
GO:0048537	mucosal-associated lymphoid tissue development	3.408947e-11
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.115865e-11
GO:0048011	nerve growth factor receptor signaling pathway	1.552378e-10
GO:0050747	positive regulation of lipoprotein metabolic process	2.607847e-10
GO:0071731	response to nitric oxide	3.065184e-10
GO:0010669	epithelial structure maintenance	3.344695e-10
GO:0035094	response to nicotine	3.941542e-10
GO:0007167	enzyme linked receptor protein signaling pathway	4.865647e-10
GO:0046628	positive regulation of insulin receptor signaling pathway	9.645349e-10
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.074568e-9
GO:0002699	positive regulation of immune effector process	1.320076e-9
GO:0007616	long-term memory	2.065069e-9
GO:0050778	positive regulation of immune response	2.138945e-9
GO:0002385	mucosal immune response	2.178114e-9
GO:0032656	regulation of interleukin-13 production	2.778898e-9
GO:0045725	positive regulation of glycogen biosynthetic process	4.929665e-9
GO:0042167	heme catabolic process	7.160204e-9
GO:0001821	histamine secretion	7.399944e-9
GO:0033559	unsaturated fatty acid metabolic process	1.070511e-8
GO:0031017	exocrine pancreas development	1.510558e-8
GO:0002443	leukocyte mediated immunity	1.552423e-8
GO:0051608	histamine transport	2.193742e-8
GO:2000465	regulation of glycogen (starch) synthase activity	2.469149e-8
GO:0048541	Peyer's patch development	3.231518e-8
GO:0046683	response to organophosphorus	3.323006e-8
GO:0006690	icosanoid metabolic process	3.994164e-8
GO:0043303	mast cell degranulation	5.985762e-8
GO:0002426	immunoglobulin production in mucosal tissue	7.117268e-8
GO:0007165	signal transduction	7.283308e-8
GO:0070875	positive regulation of glycogen metabolic process	9.081109e-8
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.037888e-7
GO:0002757	immune response-activating signal transduction	1.090920e-7
GO:0006790	sulfur compound metabolic process	1.098708e-7
GO:0060789	hair follicle placode formation	1.176443e-7
GO:0051923	sulfation	1.186140e-7
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	1.338732e-7
GO:0031347	regulation of defense response	1.423220e-7
GO:0010906	regulation of glucose metabolic process	1.792321e-7
GO:0045112	integrin biosynthetic process	2.364691e-7
GO:0002253	activation of immune response	2.389926e-7
GO:0045668	negative regulation of osteoblast differentiation	2.495636e-7
GO:0002764	immune response-regulating signaling pathway	2.754998e-7
GO:0023052	signaling	2.877756e-7
GO:0071338	positive regulation of hair follicle cell proliferation	2.913360e-7
GO:0031915	positive regulation of synaptic plasticity	2.952808e-7
GO:0010868	negative regulation of triglyceride biosynthetic process	3.798122e-7
GO:0042104	positive regulation of activated T cell proliferation	3.856622e-7
GO:0048584	positive regulation of response to stimulus	4.066627e-7
GO:0042310	vasoconstriction	4.218348e-7
GO:0047497	mitochondrion transport along microtubule	4.573046e-7
GO:0032736	positive regulation of interleukin-13 production	6.177620e-7
GO:0007623	circadian rhythm	6.528334e-7
GO:0006290	pyrimidine dimer repair	7.016871e-7
GO:0002697	regulation of immune effector process	7.798067e-7
GO:0017085	response to insecticide	8.906757e-7
GO:0017187	peptidyl-glutamic acid carboxylation	9.515679e-7
GO:0043305	negative regulation of mast cell degranulation	1.034364e-6
GO:0002274	myeloid leukocyte activation	1.054067e-6
GO:0050896	response to stimulus	1.077838e-6
GO:0043392	negative regulation of DNA binding	1.096378e-6
GO:0032916	positive regulation of transforming growth factor beta3 production	1.141906e-6
GO:0002886	regulation of myeloid leukocyte mediated immunity	1.242377e-6
GO:0060024	rhythmic synaptic transmission	1.423084e-6
GO:0051915	induction of synaptic plasticity by chemical substance	1.473000e-6
GO:0002448	mast cell mediated immunity	1.543707e-6
GO:0010907	positive regulation of glucose metabolic process	1.573643e-6
GO:0002252	immune effector process	1.579001e-6
GO:0050892	intestinal absorption	1.613208e-6
GO:0032103	positive regulation of response to external stimulus	1.627859e-6
GO:0005979	regulation of glycogen biosynthetic process	1.701726e-6
GO:0051654	establishment of mitochondrion localization	1.839617e-6
GO:0043255	regulation of carbohydrate biosynthetic process	1.906402e-6
GO:0030225	macrophage differentiation	2.311545e-6
GO:0002429	immune response-activating cell surface receptor signaling pathway	2.407634e-6
GO:0045588	positive regulation of gamma-delta T cell differentiation	2.432468e-6
GO:0007154	cell communication	2.559889e-6
GO:0002251	organ or tissue specific immune response	2.683674e-6
GO:0006788	heme oxidation	2.718675e-6
GO:0035357	peroxisome proliferator activated receptor signaling pathway	2.861745e-6
GO:0008286	insulin receptor signaling pathway	2.915985e-6
GO:0045900	negative regulation of translational elongation	2.943769e-6
GO:0002444	myeloid leukocyte mediated immunity	3.124133e-6
GO:0046889	positive regulation of lipid biosynthetic process	3.169729e-6
GO:0051656	establishment of organelle localization	3.276209e-6
GO:0001779	natural killer cell differentiation	3.300935e-6
GO:0030719	P granule organization	3.463480e-6
GO:0002694	regulation of leukocyte activation	3.516840e-6
GO:0033235	positive regulation of protein sumoylation	3.659355e-6
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	3.774311e-6
GO:0051187	cofactor catabolic process	4.597489e-6
GO:0045368	positive regulation of interleukin-13 biosynthetic process	4.696567e-6
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	4.696567e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	4.756888e-6
GO:0001894	tissue homeostasis	4.892295e-6
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.909030e-6
GO:0046544	development of secondary male sexual characteristics	5.137743e-6
GO:0048583	regulation of response to stimulus	5.163923e-6
GO:0060290	transdifferentiation	5.178618e-6
GO:0090207	regulation of triglyceride metabolic process	5.357590e-6
GO:0042508	tyrosine phosphorylation of Stat1 protein	5.392619e-6
GO:0042402	cellular biogenic amine catabolic process	5.507016e-6
GO:0002768	immune response-regulating cell surface receptor signaling pathway	5.525566e-6
GO:0010675	regulation of cellular carbohydrate metabolic process	5.652830e-6
GO:0032673	regulation of interleukin-4 production	5.656983e-6
GO:0006476	protein deacetylation	5.765215e-6
GO:0007606	sensory perception of chemical stimulus	5.820276e-6
GO:0032971	regulation of muscle filament sliding	6.270818e-6
GO:0031103	axon regeneration	6.307168e-6
GO:0061031	endodermal digestive tract morphogenesis	6.637943e-6
GO:0032352	positive regulation of hormone metabolic process	6.913678e-6
GO:0032910	regulation of transforming growth factor beta3 production	6.972710e-6
GO:0051716	cellular response to stimulus	7.222578e-6
GO:0006349	regulation of gene expression by genetic imprinting	7.515684e-6
GO:0006109	regulation of carbohydrate metabolic process	7.585935e-6
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	7.892284e-6
GO:0010676	positive regulation of cellular carbohydrate metabolic process	8.323506e-6
GO:0070741	response to interleukin-6	9.278125e-6
GO:0002891	positive regulation of immunoglobulin mediated immune response	9.308550e-6
GO:0032689	negative regulation of interferon-gamma production	9.767938e-6
GO:0008217	regulation of blood pressure	1.000287e-5
GO:0006636	unsaturated fatty acid biosynthetic process	1.012549e-5
GO:0032425	positive regulation of mismatch repair	1.058323e-5
GO:0032781	positive regulation of ATPase activity	1.068367e-5
GO:0045760	positive regulation of action potential	1.096898e-5
GO:0070873	regulation of glycogen metabolic process	1.097362e-5
GO:0035601	protein deacylation	1.137513e-5
GO:0051006	positive regulation of lipoprotein lipase activity	1.183591e-5
GO:0042503	tyrosine phosphorylation of Stat3 protein	1.287817e-5
GO:0018298	protein-chromophore linkage	1.345985e-5
GO:0046006	regulation of activated T cell proliferation	1.401119e-5
GO:0090209	negative regulation of triglyceride metabolic process	1.425625e-5
GO:0050851	antigen receptor-mediated signaling pathway	1.429544e-5
GO:0045834	positive regulation of lipid metabolic process	1.439551e-5
GO:0043179	rhythmic excitation	1.502743e-5
GO:0031349	positive regulation of defense response	1.504370e-5
GO:0050870	positive regulation of T cell activation	1.511179e-5
GO:0002696	positive regulation of leukocyte activation	1.641067e-5
GO:0042752	regulation of circadian rhythm	1.719677e-5
GO:0046208	spermine catabolic process	1.732056e-5
GO:0051958	methotrexate transport	1.740966e-5
GO:0046645	positive regulation of gamma-delta T cell activation	1.916648e-5
GO:0048675	axon extension	2.205065e-5
GO:0040018	positive regulation of multicellular organism growth	2.296089e-5
GO:0007263	nitric oxide mediated signal transduction	2.297626e-5
GO:0002708	positive regulation of lymphocyte mediated immunity	2.299587e-5
GO:0051249	regulation of lymphocyte activation	2.326462e-5
GO:0050865	regulation of cell activation	2.371596e-5
GO:0034378	chylomicron assembly	2.377606e-5
GO:0035967	cellular response to topologically incorrect protein	2.395505e-5
GO:0060155	platelet dense granule organization	2.426579e-5
GO:0006066	alcohol metabolic process	2.601161e-5
GO:0006691	leukotriene metabolic process	2.604969e-5
GO:0002553	histamine secretion by mast cell	2.670484e-5
GO:0050867	positive regulation of cell activation	2.678215e-5
GO:0070849	response to epidermal growth factor stimulus	2.698689e-5
GO:0031959	mineralocorticoid receptor signaling pathway	2.746458e-5
GO:0010893	positive regulation of steroid biosynthetic process	2.815486e-5
GO:0015817	histidine transport	2.958315e-5
GO:0035166	post-embryonic hemopoiesis	3.052116e-5
GO:0050727	regulation of inflammatory response	3.283751e-5
GO:0046886	positive regulation of hormone biosynthetic process	3.316819e-5
GO:0061162	establishment of monopolar cell polarity	3.334364e-5
GO:0045630	positive regulation of T-helper 2 cell differentiation	3.357399e-5
GO:0046456	icosanoid biosynthetic process	3.408650e-5
GO:0006952	defense response	3.433373e-5
GO:0048711	positive regulation of astrocyte differentiation	3.745440e-5
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	3.806789e-5
GO:0033194	response to hydroperoxide	3.860965e-5
GO:0042420	dopamine catabolic process	3.921851e-5
GO:0045940	positive regulation of steroid metabolic process	3.959605e-5
GO:0051251	positive regulation of lymphocyte activation	4.059454e-5
GO:0010866	regulation of triglyceride biosynthetic process	4.162546e-5
GO:0050729	positive regulation of inflammatory response	4.406757e-5
GO:0008215	spermine metabolic process	4.445265e-5
GO:0045471	response to ethanol	4.583251e-5
GO:0007567	parturition	4.738016e-5
GO:0048872	homeostasis of number of cells	4.915966e-5
GO:0007259	JAK-STAT cascade	5.060623e-5
GO:0032946	positive regulation of mononuclear cell proliferation	5.130131e-5
GO:0048710	regulation of astrocyte differentiation	5.219429e-5
GO:0006897	endocytosis	5.273954e-5
GO:0070306	lens fiber cell differentiation	5.341142e-5
GO:0007569	cell aging	5.551009e-5
GO:0060249	anatomical structure homeostasis	6.000420e-5
GO:2000273	positive regulation of receptor activity	6.128950e-5
GO:0043304	regulation of mast cell degranulation	6.224076e-5
GO:0048676	axon extension involved in development	6.343367e-5
GO:0006103	2-oxoglutarate metabolic process	6.468575e-5
GO:0045088	regulation of innate immune response	6.541101e-5
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	6.558373e-5
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	6.588742e-5
GO:0016311	dephosphorylation	6.670690e-5
GO:0070665	positive regulation of leukocyte proliferation	6.694259e-5
GO:0050863	regulation of T cell activation	6.954851e-5
GO:0033363	secretory granule organization	7.097819e-5
GO:0043206	fibril organization	7.156037e-5
GO:0080134	regulation of response to stress	7.209443e-5
GO:0050771	negative regulation of axonogenesis	7.220957e-5
GO:0010565	regulation of cellular ketone metabolic process	7.241239e-5
GO:0045721	negative regulation of gluconeogenesis	7.415712e-5
GO:0019370	leukotriene biosynthetic process	7.515562e-5
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	7.760791e-5
GO:0046173	polyol biosynthetic process	8.043352e-5
GO:0043467	regulation of generation of precursor metabolites and energy	8.309590e-5
GO:0042692	muscle cell differentiation	8.387443e-5
GO:2000210	positive regulation of anoikis	8.407612e-5
GO:0042424	catecholamine catabolic process	8.414492e-5
GO:0042045	epithelial fluid transport	8.437553e-5
GO:0010469	regulation of receptor activity	8.461838e-5
GO:0042269	regulation of natural killer cell mediated cytotoxicity	9.232078e-5
GO:0044241	lipid digestion	9.302379e-5
GO:0043279	response to alkaloid	9.339465e-5
GO:0032516	positive regulation of phosphoprotein phosphatase activity	9.341022e-5
GO:0060916	mesenchymal cell proliferation involved in lung development	9.341022e-5
GO:0050671	positive regulation of lymphocyte proliferation	9.356094e-5
GO:0045321	leukocyte activation	9.957656e-5
GO:0007173	epidermal growth factor receptor signaling pathway	1.022951e-4
GO:0065008	regulation of biological quality	1.056966e-4
GO:0043300	regulation of leukocyte degranulation	1.169714e-4
GO:0050663	cytokine secretion	1.182726e-4
GO:0030968	endoplasmic reticulum unfolded protein response	1.182726e-4
GO:0032864	activation of Cdc42 GTPase activity	1.185806e-4
GO:0051004	regulation of lipoprotein lipase activity	1.202377e-4
GO:0042592	homeostatic process	1.215361e-4
GO:0019216	regulation of lipid metabolic process	1.261664e-4
GO:0070307	lens fiber cell development	1.295764e-4
GO:0045792	negative regulation of cell size	1.385788e-4
GO:0035634	response to stilbenoid	1.394327e-4
GO:0071318	cellular response to ATP	1.408597e-4
GO:0070887	cellular response to chemical stimulus	1.409925e-4
GO:0003166	bundle of His development	1.426680e-4
GO:0061024	membrane organization	1.440604e-4
GO:0031295	T cell costimulation	1.461647e-4
GO:0006982	response to lipid hydroperoxide	1.467460e-4
GO:0014829	vascular smooth muscle contraction	1.476321e-4
GO:0006470	protein dephosphorylation	1.586916e-4
GO:0030099	myeloid cell differentiation	1.612146e-4
GO:0006693	prostaglandin metabolic process	1.621872e-4
GO:0000088	mitotic prophase	1.661731e-4
GO:0014012	peripheral nervous system axon regeneration	1.733330e-4
GO:0072678	T cell migration	1.758890e-4
GO:0014806	smooth muscle hyperplasia	1.772474e-4
GO:0031667	response to nutrient levels	1.812337e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.854430e-4
GO:0018293	protein-FAD linkage	1.854430e-4
GO:0002005	angiotensin catabolic process in blood	1.854430e-4
GO:0050852	T cell receptor signaling pathway	1.861061e-4
GO:0050768	negative regulation of neurogenesis	1.868943e-4
GO:0007635	chemosensory behavior	1.886743e-4
GO:0003014	renal system process	1.894766e-4
GO:0048247	lymphocyte chemotaxis	1.908136e-4
GO:0033189	response to vitamin A	1.925517e-4
GO:0016044	cellular membrane organization	1.936038e-4
GO:0033273	response to vitamin	1.963824e-4
GO:0002720	positive regulation of cytokine production involved in immune response	1.966980e-4
GO:0035418	protein localization to synapse	2.011437e-4
GO:0035712	T-helper 2 cell activation	2.022432e-4
GO:2000525	positive regulation of T cell costimulation	2.022432e-4
GO:0071954	chemokine (C-C motif) ligand 11 production	2.022432e-4
GO:0002215	defense response to nematode	2.022432e-4
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	2.022432e-4
GO:0035709	memory T cell activation	2.022432e-4
GO:0010830	regulation of myotube differentiation	2.047675e-4
GO:0060341	regulation of cellular localization	2.063782e-4
GO:0033007	negative regulation of mast cell activation involved in immune response	2.072015e-4
GO:0051016	barbed-end actin filament capping	2.088217e-4
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	2.122582e-4
GO:0034101	erythrocyte homeostasis	2.167075e-4
GO:0002449	lymphocyte mediated immunity	2.170707e-4
GO:0050746	regulation of lipoprotein metabolic process	2.259395e-4
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	2.278033e-4
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	2.278033e-4
GO:0021740	principal sensory nucleus of trigeminal nerve development	2.278033e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	2.278033e-4
GO:0061141	lung ciliated cell differentiation	2.278033e-4
GO:0045840	positive regulation of mitosis	2.324330e-4
GO:0007613	memory	2.354798e-4
GO:0032350	regulation of hormone metabolic process	2.362708e-4
GO:0033160	positive regulation of protein import into nucleus, translocation	2.449284e-4
GO:0002237	response to molecule of bacterial origin	2.477623e-4
GO:0007588	excretion	2.521204e-4
GO:0001798	positive regulation of type IIa hypersensitivity	2.536263e-4
GO:0043301	negative regulation of leukocyte degranulation	2.595979e-4
GO:0035264	multicellular organism growth	2.616629e-4
GO:0033006	regulation of mast cell activation involved in immune response	2.617761e-4
GO:0009650	UV protection	2.653676e-4
GO:0050690	regulation of defense response to virus by virus	2.673346e-4
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	2.689850e-4
GO:0051101	regulation of DNA binding	2.710697e-4
GO:0090030	regulation of steroid hormone biosynthetic process	2.785545e-4
GO:0048678	response to axon injury	2.840639e-4
GO:0002002	regulation of angiotensin levels in blood	2.850176e-4
GO:0060684	epithelial-mesenchymal cell signaling	2.852841e-4
GO:0006107	oxaloacetate metabolic process	2.863542e-4
GO:0045445	myoblast differentiation	2.964772e-4
GO:0030185	nitric oxide transport	3.002825e-4
GO:0051764	actin crosslink formation	3.009161e-4
GO:0070141	response to UV-A	3.113053e-4
GO:0015833	peptide transport	3.143554e-4
GO:0045089	positive regulation of innate immune response	3.206267e-4
GO:0046500	S-adenosylmethionine metabolic process	3.223052e-4
GO:0030449	regulation of complement activation	3.259010e-4
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	3.267129e-4
GO:0070309	lens fiber cell morphogenesis	3.267129e-4
GO:0032663	regulation of interleukin-2 production	3.295959e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	3.349195e-4
GO:0001817	regulation of cytokine production	3.361718e-4
GO:0035083	cilium axoneme assembly	3.367464e-4
GO:0046888	negative regulation of hormone secretion	3.373779e-4
GO:0048691	positive regulation of axon extension involved in regeneration	3.451561e-4
GO:0019056	modulation by virus of host transcription	3.451561e-4
GO:0060414	aorta smooth muscle tissue morphogenesis	3.468237e-4
GO:0090398	cellular senescence	3.478987e-4
GO:0003008	system process	3.568215e-4
GO:0030388	fructose 1,6-bisphosphate metabolic process	3.576935e-4
GO:0006909	phagocytosis	3.605243e-4
GO:0002275	myeloid cell activation involved in immune response	3.613810e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	3.641962e-4
GO:0042313	protein kinase C deactivation	3.790343e-4
GO:0031583	activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway	3.790343e-4
GO:0032496	response to lipopolysaccharide	3.880234e-4
GO:0032753	positive regulation of interleukin-4 production	3.902934e-4
GO:0015866	ADP transport	3.931153e-4
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	3.964118e-4
GO:0009617	response to bacterium	3.990321e-4
GO:0072593	reactive oxygen species metabolic process	4.073814e-4
GO:0060426	lung vasculature development	4.271005e-4
GO:0048625	myoblast cell fate commitment	4.393932e-4
GO:0034976	response to endoplasmic reticulum stress	4.438536e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	4.533233e-4
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	4.582216e-4
GO:0051146	striated muscle cell differentiation	4.585707e-4
GO:0031343	positive regulation of cell killing	4.591045e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	4.604826e-4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.606031e-4
GO:0048690	regulation of axon extension involved in regeneration	4.633037e-4
GO:0003093	regulation of glomerular filtration	4.674265e-4
GO:0016049	cell growth	4.711456e-4
GO:0006984	ER-nucleus signaling pathway	4.724766e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	4.751061e-4
GO:0006021	inositol biosynthetic process	4.753637e-4
GO:0001775	cell activation	4.767750e-4
GO:0072201	negative regulation of mesenchymal cell proliferation	4.807769e-4
GO:0043029	T cell homeostasis	4.971290e-4
GO:0002920	regulation of humoral immune response	5.121936e-4
GO:0050878	regulation of body fluid levels	5.171970e-4
GO:0006029	proteoglycan metabolic process	5.200352e-4
GO:0033233	regulation of protein sumoylation	5.206531e-4
GO:0030204	chondroitin sulfate metabolic process	5.272374e-4
GO:0001970	positive regulation of activation of membrane attack complex	5.300877e-4
GO:0070293	renal absorption	5.341653e-4
GO:0007016	cytoskeletal anchoring at plasma membrane	5.427965e-4
GO:0016925	protein sumoylation	5.432524e-4
GO:0051640	organelle localization	5.490475e-4
GO:0001819	positive regulation of cytokine production	5.495408e-4
GO:0055010	ventricular cardiac muscle tissue morphogenesis	5.509483e-4
GO:0072676	lymphocyte migration	5.912718e-4
GO:0002019	regulation of renal output by angiotensin	5.929149e-4
GO:0030201	heparan sulfate proteoglycan metabolic process	5.944177e-4
GO:0007260	tyrosine phosphorylation of STAT protein	5.980238e-4
GO:0016575	histone deacetylation	6.020798e-4
GO:0046883	regulation of hormone secretion	6.198109e-4
GO:0021884	forebrain neuron development	6.222036e-4
GO:0030097	hemopoiesis	6.225304e-4
GO:0007611	learning or memory	6.280293e-4
GO:0046849	bone remodeling	6.339659e-4
GO:0000072	M phase specific microtubule process	6.501052e-4
GO:0048199	vesicle targeting, to, from or within Golgi	6.626110e-4
GO:0009605	response to external stimulus	6.801246e-4
GO:0042137	sequestering of neurotransmitter	6.850012e-4
GO:0040023	establishment of nucleus localization	6.917897e-4
GO:0045047	protein targeting to ER	6.984668e-4
GO:0046890	regulation of lipid biosynthetic process	7.091142e-4
GO:0007608	sensory perception of smell	7.152017e-4
GO:0071514	genetic imprinting	7.164854e-4
GO:0045923	positive regulation of fatty acid metabolic process	7.255088e-4
GO:0051647	nucleus localization	7.317177e-4
GO:0019935	cyclic-nucleotide-mediated signaling	7.430023e-4
GO:0032869	cellular response to insulin stimulus	7.527937e-4
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	7.629264e-4
GO:0060742	epithelial cell differentiation involved in prostate gland development	7.641131e-4
GO:0018200	peptidyl-glutamic acid modification	7.670447e-4
GO:0046626	regulation of insulin receptor signaling pathway	7.748758e-4
GO:0001909	leukocyte mediated cytotoxicity	7.755843e-4
GO:0001757	somite specification	7.874990e-4
GO:0007610	behavior	7.972540e-4
GO:0032633	interleukin-4 production	8.001765e-4
GO:0001865	NK T cell differentiation	8.001765e-4
GO:0006821	chloride transport	8.159974e-4
GO:0045777	positive regulation of blood pressure	8.208021e-4
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	8.384912e-4
GO:0043248	proteasome assembly	8.429374e-4
GO:0006101	citrate metabolic process	8.429374e-4
GO:0060612	adipose tissue development	8.494915e-4
GO:0046813	virion attachment, binding of host cell surface receptor	8.590803e-4
GO:0045199	maintenance of epithelial cell apical/basal polarity	8.611803e-4
GO:0009051	pentose-phosphate shunt, oxidative branch	8.611803e-4
GO:0009991	response to extracellular stimulus	8.896296e-4
GO:0072044	collecting duct development	8.944955e-4
GO:0048588	developmental cell growth	8.995006e-4
GO:0008063	Toll signaling pathway	9.002068e-4
GO:0044240	multicellular organismal lipid catabolic process	9.019588e-4
GO:0048016	inositol phosphate-mediated signaling	9.413256e-4
GO:0046655	folic acid metabolic process	9.483967e-4
GO:0033003	regulation of mast cell activation	9.507279e-4
GO:0002885	positive regulation of hypersensitivity	9.591889e-4
GO:0046498	S-adenosylhomocysteine metabolic process	9.640806e-4
GO:0035556	intracellular signal transduction	9.644992e-4
GO:0006575	cellular modified amino acid metabolic process	9.724320e-4
GO:0002790	peptide secretion	9.816290e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	9.861628e-4
GO:0048265	response to pain	1.010443e-3
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.016472e-3
GO:0072376	protein activation cascade	1.020477e-3
GO:0060137	maternal process involved in parturition	1.039409e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.040206e-3
GO:0006598	polyamine catabolic process	1.041178e-3
GO:0035269	protein O-linked mannosylation	1.075906e-3
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.075906e-3
GO:0001906	cell killing	1.076082e-3
GO:0019062	virion attachment to host cell surface receptor	1.085834e-3
GO:0002520	immune system development	1.086912e-3
GO:0032929	negative regulation of superoxide anion generation	1.089402e-3
GO:0071715	icosanoid transport	1.097993e-3
GO:0031345	negative regulation of cell projection organization	1.104025e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	1.114668e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	1.121224e-3
GO:0031175	neuron projection development	1.121964e-3
GO:0045685	regulation of glial cell differentiation	1.131533e-3
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.138459e-3
GO:0019932	second-messenger-mediated signaling	1.146705e-3
GO:0042136	neurotransmitter biosynthetic process	1.146953e-3
GO:0035413	positive regulation of catenin import into nucleus	1.146953e-3
GO:0006692	prostanoid metabolic process	1.147102e-3
GO:0071375	cellular response to peptide hormone stimulus	1.152967e-3
GO:0090026	positive regulation of monocyte chemotaxis	1.184759e-3
GO:0045600	positive regulation of fat cell differentiation	1.185917e-3
GO:0042221	response to chemical stimulus	1.193458e-3
GO:0006885	regulation of pH	1.195852e-3
GO:0007155	cell adhesion	1.204691e-3
GO:0016192	vesicle-mediated transport	1.208126e-3
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	1.208538e-3
GO:0006106	fumarate metabolic process	1.209615e-3
GO:0015844	monoamine transport	1.223597e-3
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.228808e-3
GO:0009914	hormone transport	1.253192e-3
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.261086e-3
GO:0042102	positive regulation of T cell proliferation	1.265018e-3
GO:0050862	positive regulation of T cell receptor signaling pathway	1.301369e-3
GO:0060297	regulation of sarcomere organization	1.320106e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	1.326615e-3
GO:0060306	regulation of membrane repolarization	1.338191e-3
GO:0007015	actin filament organization	1.347705e-3
GO:0051017	actin filament bundle assembly	1.378789e-3
GO:2000612	regulation of thyroid-stimulating hormone secretion	1.380309e-3
GO:0032637	interleukin-8 production	1.409130e-3
GO:0001886	endothelial cell morphogenesis	1.411557e-3
GO:0071679	commissural neuron axon guidance	1.411557e-3
GO:0010898	positive regulation of triglyceride catabolic process	1.420324e-3
GO:0010954	positive regulation of protein processing	1.423265e-3
GO:0045739	positive regulation of DNA repair	1.431844e-3
GO:0048871	multicellular organismal homeostasis	1.438538e-3
GO:0030538	embryonic genitalia morphogenesis	1.439105e-3
GO:0006007	glucose catabolic process	1.450606e-3
GO:0015837	amine transport	1.456339e-3
GO:0045622	regulation of T-helper cell differentiation	1.483978e-3
GO:0006954	inflammatory response	1.484645e-3
GO:0055123	digestive system development	1.486263e-3
GO:0002089	lens morphogenesis in camera-type eye	1.490072e-3
GO:0071705	nitrogen compound transport	1.518777e-3
GO:0090136	epithelial cell-cell adhesion	1.533805e-3
GO:0048857	neural nucleus development	1.548327e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	1.556406e-3
GO:0070295	renal water absorption	1.578293e-3
GO:0008015	blood circulation	1.582536e-3
GO:0002088	lens development in camera-type eye	1.591264e-3
GO:0090322	regulation of superoxide metabolic process	1.598632e-3
GO:0006471	protein ADP-ribosylation	1.599885e-3
GO:0040007	growth	1.605440e-3
GO:0032862	activation of Rho GTPase activity	1.612265e-3
GO:0032674	regulation of interleukin-5 production	1.614756e-3
GO:0035409	histone H3-Y41 phosphorylation	1.629819e-3
GO:0008636	activation of caspase activity by protein phosphorylation	1.629819e-3
GO:0003073	regulation of systemic arterial blood pressure	1.636794e-3
GO:0032101	regulation of response to external stimulus	1.641498e-3
GO:0034134	toll-like receptor 2 signaling pathway	1.669318e-3
GO:0034130	toll-like receptor 1 signaling pathway	1.669318e-3
GO:0048384	retinoic acid receptor signaling pathway	1.674593e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042135	neurotransmitter catabolic process	5.814742e-17
GO:0042133	neurotransmitter metabolic process	1.625236e-13
GO:0006581	acetylcholine catabolic process	3.177491e-13
GO:0008291	acetylcholine metabolic process	8.280452e-12
GO:2000253	positive regulation of feeding behavior	9.007072e-10
GO:2000507	positive regulation of energy homeostasis	9.007072e-10
GO:0045212	neurotransmitter receptor biosynthetic process	9.945031e-9
GO:0030299	intestinal cholesterol absorption	5.311963e-8
GO:0070252	actin-mediated cell contraction	7.108710e-8
GO:0071670	smooth muscle cell chemotaxis	7.168768e-8
GO:0060981	cell migration involved in coronary angiogenesis	7.168768e-8
GO:0060561	apoptosis involved in morphogenesis	8.811427e-8
GO:2000505	regulation of energy homeostasis	9.865562e-8
GO:0045933	positive regulation of muscle contraction	9.929495e-8
GO:0034767	positive regulation of ion transmembrane transport	1.805215e-7
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.979370e-7
GO:0006200	ATP catabolic process	2.321684e-7
GO:0010949	negative regulation of intestinal phytosterol absorption	3.419474e-7
GO:0045796	negative regulation of intestinal cholesterol absorption	3.419474e-7
GO:0030036	actin cytoskeleton organization	4.185390e-7
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	4.241433e-7
GO:0032418	lysosome localization	4.241433e-7
GO:0033275	actin-myosin filament sliding	4.865548e-7
GO:0030029	actin filament-based process	5.349123e-7
GO:0006297	nucleotide-excision repair, DNA gap filling	7.044409e-7
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	8.647282e-7
GO:0019695	choline metabolic process	1.547261e-6
GO:0090280	positive regulation of calcium ion import	1.648992e-6
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.648992e-6
GO:0003229	ventricular cardiac muscle tissue development	1.740589e-6
GO:0090361	regulation of platelet-derived growth factor production	2.900669e-6
GO:0003015	heart process	3.555011e-6
GO:0001516	prostaglandin biosynthetic process	4.253125e-6
GO:0071877	regulation of adrenergic receptor signaling pathway	4.728047e-6
GO:0006540	glutamate decarboxylation to succinate	5.056571e-6
GO:0072539	T-helper 17 cell differentiation	5.056571e-6
GO:0030239	myofibril assembly	6.449267e-6
GO:0010631	epithelial cell migration	6.500977e-6
GO:0010842	retina layer formation	7.380483e-6
GO:0035621	ER to Golgi ceramide transport	8.351542e-6
GO:0030004	cellular monovalent inorganic cation homeostasis	9.817493e-6
GO:0010623	developmental programmed cell death	1.067519e-5
GO:2000249	regulation of actin cytoskeleton reorganization	1.359152e-5
GO:0006308	DNA catabolic process	1.364631e-5
GO:0060457	negative regulation of digestive system process	1.824837e-5
GO:0006693	prostaglandin metabolic process	1.946695e-5
GO:0002027	regulation of heart rate	2.078421e-5
GO:0045851	pH reduction	2.115649e-5
GO:0072110	glomerular mesangial cell proliferation	2.147509e-5
GO:0006289	nucleotide-excision repair	2.824694e-5
GO:0048738	cardiac muscle tissue development	2.877215e-5
GO:0030641	regulation of cellular pH	2.926686e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	3.001587e-5
GO:0035886	vascular smooth muscle cell differentiation	3.037844e-5
GO:0055002	striated muscle cell development	3.053811e-5
GO:0051452	intracellular pH reduction	3.123026e-5
GO:0060420	regulation of heart growth	3.242328e-5
GO:0061072	iris morphogenesis	3.320398e-5
GO:0055010	ventricular cardiac muscle tissue morphogenesis	3.705354e-5
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	3.777514e-5
GO:0071879	positive regulation of adrenergic receptor signaling pathway	3.777514e-5
GO:0030098	lymphocyte differentiation	3.914911e-5
GO:0060042	retina morphogenesis in camera-type eye	4.016600e-5
GO:0031032	actomyosin structure organization	4.063207e-5
GO:0060427	lung connective tissue development	4.309742e-5
GO:0046456	icosanoid biosynthetic process	4.387459e-5
GO:0090076	relaxation of skeletal muscle	4.689122e-5
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	4.689122e-5
GO:0044027	hypermethylation of CpG island	4.700736e-5
GO:0055021	regulation of cardiac muscle tissue growth	4.845127e-5
GO:0014819	regulation of skeletal muscle contraction	4.853590e-5
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	5.178566e-5
GO:0008219	cell death	5.339843e-5
GO:0016338	calcium-independent cell-cell adhesion	5.541517e-5
GO:0046037	GMP metabolic process	5.598020e-5
GO:0009056	catabolic process	5.653469e-5
GO:0007283	spermatogenesis	5.972868e-5
GO:0016265	death	6.122188e-5
GO:0060047	heart contraction	6.208426e-5
GO:0012501	programmed cell death	7.634741e-5
GO:0043462	regulation of ATPase activity	7.727382e-5
GO:0048739	cardiac muscle fiber development	8.622080e-5
GO:0001708	cell fate specification	9.088059e-5
GO:0042402	cellular biogenic amine catabolic process	9.385740e-5
GO:0006690	icosanoid metabolic process	9.470953e-5
GO:0045989	positive regulation of striated muscle contraction	9.552985e-5
GO:0042093	T-helper cell differentiation	9.559265e-5
GO:0030048	actin filament-based movement	9.750230e-5
GO:0051001	negative regulation of nitric-oxide synthase activity	1.067956e-4
GO:0006942	regulation of striated muscle contraction	1.076819e-4
GO:0046427	positive regulation of JAK-STAT cascade	1.108678e-4
GO:0055001	muscle cell development	1.156216e-4
GO:0006915	apoptosis	1.188897e-4
GO:0055003	cardiac myofibril assembly	1.290727e-4
GO:0006663	platelet activating factor biosynthetic process	1.303238e-4
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	1.360266e-4
GO:0006904	vesicle docking involved in exocytosis	1.377232e-4
GO:0006636	unsaturated fatty acid biosynthetic process	1.483700e-4
GO:0000302	response to reactive oxygen species	1.514129e-4
GO:0007522	visceral muscle development	1.618756e-4
GO:2000573	positive regulation of DNA biosynthetic process	1.681345e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.681345e-4
GO:0090279	regulation of calcium ion import	1.698515e-4
GO:0030049	muscle filament sliding	1.747261e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	1.750844e-4
GO:0070358	actin polymerization-dependent cell motility	1.785157e-4
GO:0055026	negative regulation of cardiac muscle tissue development	1.785157e-4
GO:0006649	phospholipid transfer to membrane	1.785157e-4
GO:0042938	dipeptide transport	1.785157e-4
GO:0045987	positive regulation of smooth muscle contraction	1.839645e-4
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	1.950062e-4
GO:0070165	positive regulation of adiponectin secretion	1.986863e-4
GO:0070535	histone H2A K63-linked ubiquitination	1.986863e-4
GO:0033031	positive regulation of neutrophil apoptosis	1.986863e-4
GO:0006259	DNA metabolic process	2.060634e-4
GO:0071529	cementum mineralization	2.098511e-4
GO:0090130	tissue migration	2.115585e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	2.134444e-4
GO:0035845	photoreceptor cell outer segment organization	2.134444e-4
GO:0055007	cardiac muscle cell differentiation	2.155840e-4
GO:0055008	cardiac muscle tissue morphogenesis	2.193575e-4
GO:0035051	cardiac cell differentiation	2.292722e-4
GO:0010269	response to selenium ion	2.496988e-4
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	2.570370e-4
GO:0002021	response to dietary excess	2.618710e-4
GO:0045213	neurotransmitter receptor metabolic process	2.732387e-4
GO:0009410	response to xenobiotic stimulus	2.850134e-4
GO:0072593	reactive oxygen species metabolic process	2.887644e-4
GO:0003218	cardiac left ventricle formation	3.096845e-4
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	3.130768e-4
GO:0046649	lymphocyte activation	3.259974e-4
GO:0071866	negative regulation of apoptosis in bone marrow	3.270424e-4
GO:0055024	regulation of cardiac muscle tissue development	3.271443e-4
GO:0002293	alpha-beta T cell differentiation involved in immune response	3.400409e-4
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	3.630177e-4
GO:0014909	smooth muscle cell migration	3.647169e-4
GO:0003278	apoptosis involved in heart morphogenesis	3.740410e-4
GO:0042743	hydrogen peroxide metabolic process	3.912136e-4
GO:0042891	antibiotic transport	3.956880e-4
GO:0046034	ATP metabolic process	4.062034e-4
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	4.137560e-4
GO:0032914	positive regulation of transforming growth factor beta1 production	4.309427e-4
GO:0046686	response to cadmium ion	4.329762e-4
GO:0001885	endothelial cell development	4.496897e-4
GO:0044248	cellular catabolic process	4.516419e-4
GO:0060947	cardiac vascular smooth muscle cell differentiation	4.557440e-4
GO:0033197	response to vitamin E	4.572357e-4
GO:0021861	forebrain radial glial cell differentiation	4.572357e-4
GO:0060044	negative regulation of cardiac muscle cell proliferation	4.693527e-4
GO:0051354	negative regulation of oxidoreductase activity	4.693527e-4
GO:0060969	negative regulation of gene silencing	4.736465e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	4.930529e-4
GO:0060043	regulation of cardiac muscle cell proliferation	5.078008e-4
GO:0010614	negative regulation of cardiac muscle hypertrophy	5.151159e-4
GO:0043248	proteasome assembly	5.500329e-4
GO:0002287	alpha-beta T cell activation involved in immune response	5.626219e-4
GO:0032411	positive regulation of transporter activity	5.796300e-4
GO:0001701	in utero embryonic development	5.840320e-4
GO:0018108	peptidyl-tyrosine phosphorylation	6.111199e-4
GO:0072109	glomerular mesangium development	6.175980e-4
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	6.175980e-4
GO:0033591	response to L-ascorbic acid	6.261338e-4
GO:0035691	macrophage migration inhibitory factor signaling pathway	6.280488e-4
GO:0055006	cardiac cell development	6.311111e-4
GO:0003166	bundle of His development	6.374233e-4
GO:0060479	lung cell differentiation	6.471964e-4
GO:0007340	acrosome reaction	6.926861e-4
GO:0060710	chorio-allantoic fusion	7.167516e-4
GO:0010312	detoxification of zinc ion	7.168625e-4
GO:0045900	negative regulation of translational elongation	7.212536e-4
GO:0019428	allantoin biosynthetic process	7.212536e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	7.212536e-4
GO:0018293	protein-FAD linkage	7.212536e-4
GO:0032720	negative regulation of tumor necrosis factor production	7.515228e-4
GO:0051494	negative regulation of cytoskeleton organization	7.516612e-4
GO:0045823	positive regulation of heart contraction	7.597683e-4
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	7.724124e-4
GO:0010639	negative regulation of organelle organization	7.731884e-4
GO:0045214	sarcomere organization	7.754683e-4
GO:0043949	regulation of cAMP-mediated signaling	7.786754e-4
GO:0071874	cellular response to norepinephrine stimulus	8.333538e-4
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	8.587377e-4
GO:0045163	clustering of voltage-gated potassium channels	8.587377e-4
GO:0032703	negative regulation of interleukin-2 production	8.588094e-4
GO:0051272	positive regulation of cellular component movement	8.697657e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	8.711296e-4
GO:0030217	T cell differentiation	8.769396e-4
GO:0009886	post-embryonic morphogenesis	8.791782e-4
GO:0048278	vesicle docking	9.059850e-4
GO:0007525	somatic muscle development	9.183999e-4
GO:0033280	response to vitamin D	9.424754e-4
GO:0006290	pyrimidine dimer repair	9.483731e-4
GO:0060088	auditory receptor cell stereocilium organization	9.485026e-4
GO:0055013	cardiac muscle cell development	9.534807e-4
GO:0030509	BMP signaling pathway	9.941676e-4
GO:0007624	ultradian rhythm	1.011516e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	1.038541e-3
GO:0071218	cellular response to misfolded protein	1.068831e-3
GO:0070684	seminal clot liquefaction	1.092869e-3
GO:2000009	negative regulation of protein localization at cell surface	1.092869e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	1.092869e-3
GO:0006882	cellular zinc ion homeostasis	1.111296e-3
GO:0032287	peripheral nervous system myelin maintenance	1.160484e-3
GO:0006979	response to oxidative stress	1.169304e-3
GO:0014741	negative regulation of muscle hypertrophy	1.171432e-3
GO:0032006	regulation of TOR signaling cascade	1.184841e-3
GO:0071345	cellular response to cytokine stimulus	1.190334e-3
GO:0021960	anterior commissure morphogenesis	1.199342e-3
GO:0002262	myeloid cell homeostasis	1.219063e-3
GO:0035137	hindlimb morphogenesis	1.249573e-3
GO:0060259	regulation of feeding behavior	1.251784e-3
GO:0090362	positive regulation of platelet-derived growth factor production	1.254109e-3
GO:0090271	positive regulation of fibroblast growth factor production	1.254109e-3
GO:0090336	positive regulation of brown fat cell differentiation	1.254109e-3
GO:0045591	positive regulation of regulatory T cell differentiation	1.264752e-3
GO:0015850	organic alcohol transport	1.273740e-3
GO:0060428	lung epithelium development	1.294044e-3
GO:0012502	induction of programmed cell death	1.319532e-3
GO:0001706	endoderm formation	1.344530e-3
GO:0051453	regulation of intracellular pH	1.351591e-3
GO:0007512	adult heart development	1.364417e-3
GO:0033151	V(D)J recombination	1.410958e-3
GO:0006917	induction of apoptosis	1.428307e-3
GO:0033152	immunoglobulin V(D)J recombination	1.430713e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	1.474587e-3
GO:0002064	epithelial cell development	1.480430e-3
GO:0051176	positive regulation of sulfur metabolic process	1.482289e-3
GO:0035441	cell migration involved in vasculogenesis	1.482289e-3
GO:0007271	synaptic transmission, cholinergic	1.486058e-3
GO:0007565	female pregnancy	1.499389e-3
GO:0051583	dopamine uptake	1.515353e-3
GO:0032332	positive regulation of chondrocyte differentiation	1.538266e-3
GO:0050434	positive regulation of viral transcription	1.581634e-3
GO:0002065	columnar/cuboidal epithelial cell differentiation	1.625513e-3
GO:0045321	leukocyte activation	1.652527e-3
GO:0031936	negative regulation of chromatin silencing	1.659213e-3
GO:0015793	glycerol transport	1.714293e-3
GO:0045766	positive regulation of angiogenesis	1.784857e-3
GO:0060039	pericardium development	1.799696e-3
GO:0051013	microtubule severing	1.818444e-3
GO:0070163	regulation of adiponectin secretion	1.829237e-3
GO:0000059	protein import into nucleus, docking	1.829237e-3
GO:0032769	negative regulation of monooxygenase activity	1.841217e-3
GO:0007021	tubulin complex assembly	1.860236e-3
GO:0002315	marginal zone B cell differentiation	1.860236e-3
GO:0006007	glucose catabolic process	1.870124e-3
GO:0032321	positive regulation of Rho GTPase activity	1.879988e-3
GO:0006885	regulation of pH	1.926067e-3
GO:0032231	regulation of actin filament bundle assembly	1.999485e-3
GO:0035024	negative regulation of Rho protein signal transduction	2.012204e-3
GO:0050892	intestinal absorption	2.018518e-3
GO:0002335	mature B cell differentiation	2.061620e-3
GO:0003013	circulatory system process	2.074518e-3
GO:0070542	response to fatty acid	2.084248e-3
GO:0046007	negative regulation of activated T cell proliferation	2.106890e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	2.106890e-3
GO:0002093	auditory receptor cell morphogenesis	2.112648e-3
GO:0019320	hexose catabolic process	2.138496e-3
GO:0007042	lysosomal lumen acidification	2.156976e-3
GO:2000725	regulation of cardiac muscle cell differentiation	2.163593e-3
GO:0002329	pre-B cell differentiation	2.177973e-3
GO:0007224	smoothened signaling pathway	2.197264e-3
GO:0050689	negative regulation of defense response to virus by host	2.199920e-3
GO:0018158	protein oxidation	2.199920e-3
GO:0072573	tolerance induction to lipopolysaccharide	2.233887e-3
GO:2000349	negative regulation of CD40 signaling pathway	2.233887e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.233887e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.233887e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	2.233887e-3
GO:0002632	negative regulation of granuloma formation	2.233887e-3
GO:0034421	post-translational protein acetylation	2.259900e-3
GO:0002851	positive regulation of peripheral T cell tolerance induction	2.259900e-3
GO:0032819	positive regulation of natural killer cell proliferation	2.283514e-3
GO:0021943	formation of radial glial scaffolds	2.283514e-3
GO:0048146	positive regulation of fibroblast proliferation	2.291723e-3
GO:0030223	neutrophil differentiation	2.310624e-3
GO:0034976	response to endoplasmic reticulum stress	2.368124e-3
GO:0008217	regulation of blood pressure	2.397061e-3
GO:0043666	regulation of phosphoprotein phosphatase activity	2.404490e-3
GO:0022408	negative regulation of cell-cell adhesion	2.408525e-3
GO:0031954	positive regulation of protein autophosphorylation	2.422084e-3
GO:0002507	tolerance induction	2.430637e-3
GO:0031952	regulation of protein autophosphorylation	2.469291e-3
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	2.488741e-3
GO:0007566	embryo implantation	2.501079e-3
GO:0006941	striated muscle contraction	2.501672e-3
GO:0006750	glutathione biosynthetic process	2.540958e-3
GO:0055069	zinc ion homeostasis	2.546929e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	2.557630e-3
GO:0070509	calcium ion import	2.586301e-3
GO:0033240	positive regulation of cellular amine metabolic process	2.586301e-3
GO:0007276	gamete generation	2.599393e-3
GO:0043010	camera-type eye development	2.608926e-3
GO:0048293	regulation of isotype switching to IgE isotypes	2.661170e-3
GO:0042668	auditory receptor cell fate determination	2.673550e-3
GO:0022011	myelination in peripheral nervous system	2.710119e-3
GO:0021781	glial cell fate commitment	2.717042e-3
GO:0009064	glutamine family amino acid metabolic process	2.746595e-3
GO:0045601	regulation of endothelial cell differentiation	2.752975e-3
GO:0010821	regulation of mitochondrion organization	2.761316e-3
GO:0060041	retina development in camera-type eye	2.793207e-3
GO:0048294	negative regulation of isotype switching to IgE isotypes	2.866137e-3
GO:0060487	lung epithelial cell differentiation	2.871302e-3
GO:0071895	odontoblast differentiation	2.872509e-3
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.872509e-3
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.872509e-3
GO:0033127	regulation of histone phosphorylation	2.876915e-3
GO:0031117	positive regulation of microtubule depolymerization	2.876915e-3
GO:0045793	positive regulation of cell size	2.880220e-3
GO:0006749	glutathione metabolic process	2.881232e-3
GO:0070670	response to interleukin-4	2.923140e-3
GO:0045988	negative regulation of striated muscle contraction	2.948961e-3
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	2.989094e-3
GO:0006256	UDP catabolic process	3.006696e-3
GO:0009405	pathogenesis	3.006696e-3
GO:0046164	alcohol catabolic process	3.015893e-3
GO:0008016	regulation of heart contraction	3.042140e-3
GO:0060019	radial glial cell differentiation	3.075014e-3
GO:0006177	GMP biosynthetic process	3.092377e-3
GO:0010927	cellular component assembly involved in morphogenesis	3.137963e-3
GO:0060713	labyrinthine layer morphogenesis	3.166164e-3
GO:0048841	regulation of axon extension involved in axon guidance	3.200897e-3
GO:0044241	lipid digestion	3.281656e-3
GO:0032792	negative regulation of CREB transcription factor activity	3.294050e-3
GO:0014045	establishment of endothelial blood-brain barrier	3.294050e-3
GO:0006538	glutamate catabolic process	3.315571e-3
GO:0032268	regulation of cellular protein metabolic process	3.325719e-3
GO:0046365	monosaccharide catabolic process	3.392078e-3
GO:0042113	B cell activation	3.413449e-3
GO:0002432	granuloma formation	3.421914e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	3.492265e-3
GO:0061153	trachea gland development	3.563070e-3
GO:0048069	eye pigmentation	3.563070e-3
GO:0035116	embryonic hindlimb morphogenesis	3.568410e-3
GO:0014075	response to amine stimulus	3.582312e-3
GO:0001704	formation of primary germ layer	3.628643e-3
GO:0061188	negative regulation of chromatin silencing at rDNA	3.718057e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3.718057e-3
GO:0002725	negative regulation of T cell cytokine production	3.802938e-3
GO:0009088	threonine biosynthetic process	3.868996e-3
GO:0070060	'de novo' actin filament nucleation	3.868996e-3
GO:0003273	cell migration involved in endocardial cushion formation	3.868996e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	3.949808e-3
GO:2000147	positive regulation of cell motility	4.038348e-3
GO:0046112	nucleobase biosynthetic process	4.051832e-3
GO:0050909	sensory perception of taste	4.053463e-3
GO:0097150	neuronal stem cell maintenance	4.113920e-3
GO:0003382	epithelial cell morphogenesis	4.147809e-3
GO:0001932	regulation of protein phosphorylation	4.205384e-3
GO:0072523	purine-containing compound catabolic process	4.241522e-3
GO:0010963	regulation of L-arginine import	4.310793e-3
GO:0015722	canalicular bile acid transport	4.310793e-3
GO:0051125	regulation of actin nucleation	4.397773e-3
GO:0035265	organ growth	4.407277e-3
GO:0055067	monovalent inorganic cation homeostasis	4.425257e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	4.434603e-3
GO:0031935	regulation of chromatin silencing	4.452285e-3
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	4.461448e-3
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	4.461448e-3
GO:2000980	regulation of inner ear receptor cell differentiation	4.461448e-3
GO:0021740	principal sensory nucleus of trigeminal nerve development	4.461448e-3
GO:0061141	lung ciliated cell differentiation	4.461448e-3
GO:2000347	positive regulation of hepatocyte proliferation	4.461448e-3
GO:0060415	muscle tissue morphogenesis	4.461942e-3
GO:0006195	purine nucleotide catabolic process	4.493944e-3
GO:0051788	response to misfolded protein	4.546180e-3
GO:0040017	positive regulation of locomotion	4.560328e-3
GO:0071624	positive regulation of granulocyte chemotaxis	4.669598e-3
GO:0071105	response to interleukin-11	4.669598e-3
GO:0031629	synaptic vesicle fusion to presynaptic membrane	4.669598e-3
GO:0030818	negative regulation of cAMP biosynthetic process	4.752084e-3
GO:0006566	threonine metabolic process	4.769631e-3
GO:0006014	D-ribose metabolic process	4.865082e-3
GO:0051146	striated muscle cell differentiation	4.869428e-3
GO:0071870	cellular response to catecholamine stimulus	4.893768e-3
GO:0002832	negative regulation of response to biotic stimulus	4.911401e-3
GO:0072273	metanephric nephron morphogenesis	4.924698e-3
GO:0003338	metanephros morphogenesis	4.973896e-3
GO:0010822	positive regulation of mitochondrion organization	4.977778e-3
GO:0010627	regulation of intracellular protein kinase cascade	5.019869e-3
GO:0006906	vesicle fusion	5.034576e-3
GO:2000345	regulation of hepatocyte proliferation	5.055735e-3
GO:0060117	auditory receptor cell development	5.074372e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.107106e-3
GO:0006283	transcription-coupled nucleotide-excision repair	5.107106e-3
GO:0006360	transcription from RNA polymerase I promoter	5.204846e-3
GO:0018345	protein palmitoylation	5.215465e-3
GO:0045077	negative regulation of interferon-gamma biosynthetic process	5.226663e-3
GO:0019220	regulation of phosphate metabolic process	5.318079e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5.323817e-3
GO:0003214	cardiac left ventricle morphogenesis	5.355771e-3
GO:0006096	glycolysis	5.399626e-3
GO:0043171	peptide catabolic process	5.444482e-3
GO:0006888	ER to Golgi vesicle-mediated transport	5.450938e-3
GO:0032776	DNA methylation on cytosine	5.482557e-3
GO:0015791	polyol transport	5.561484e-3
GO:0006474	N-terminal protein amino acid acetylation	5.561484e-3
GO:0009750	response to fructose stimulus	5.684028e-3
GO:0042439	ethanolamine-containing compound metabolic process	5.792694e-3
GO:0048241	epinephrine transport	5.838438e-3
GO:0048548	regulation of pinocytosis	5.884909e-3
GO:0042415	norepinephrine metabolic process	5.948308e-3
GO:0051937	catecholamine transport	5.948308e-3
GO:0043048	dolichyl monophosphate biosynthetic process	6.011062e-3
GO:0034971	histone H3-R17 methylation	6.011062e-3
GO:0009691	cytokinin biosynthetic process	6.011062e-3
GO:0007010	cytoskeleton organization	6.016231e-3
GO:0051890	regulation of cardioblast differentiation	6.029214e-3
GO:0032817	regulation of natural killer cell proliferation	6.054319e-3
GO:0050953	sensory perception of light stimulus	6.181362e-3
GO:0035136	forelimb morphogenesis	6.195918e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	6.343069e-3
GO:0010043	response to zinc ion	6.366923e-3
GO:0043951	negative regulation of cAMP-mediated signaling	6.377681e-3
GO:0007369	gastrulation	6.441373e-3
GO:0000082	G1/S transition of mitotic cell cycle	6.446238e-3
GO:0006914	autophagy	6.446887e-3
GO:0090023	positive regulation of neutrophil chemotaxis	6.478279e-3
GO:0031110	regulation of microtubule polymerization or depolymerization	6.515949e-3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	6.579640e-3
GO:0017156	calcium ion-dependent exocytosis	6.581405e-3
GO:0033077	T cell differentiation in thymus	6.617027e-3
GO:0001886	endothelial cell morphogenesis	6.634442e-3
GO:0010424	DNA methylation on cytosine within a CG sequence	6.654294e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	6.780954e-3
GO:0071109	superior temporal gyrus development	6.786749e-3
GO:0048034	heme O biosynthetic process	6.786749e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	6.786749e-3
GO:0070972	protein localization in endoplasmic reticulum	6.794671e-3
GO:0046425	regulation of JAK-STAT cascade	6.799744e-3
GO:0060929	atrioventricular node cell fate commitment	6.815767e-3
GO:0090042	tubulin deacetylation	6.815767e-3
GO:0070846	Hsp90 deacetylation	6.815767e-3
GO:0060928	atrioventricular node cell development	6.815767e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	6.815767e-3
GO:0003342	proepicardium development	6.815767e-3
GO:0042073	intraflagellar transport	6.815767e-3
GO:0007015	actin filament organization	6.833251e-3
GO:0042424	catecholamine catabolic process	6.843248e-3
GO:0045603	positive regulation of endothelial cell differentiation	6.876046e-3
GO:0045682	regulation of epidermis development	6.907055e-3
GO:0042487	regulation of odontogenesis of dentine-containing tooth	6.932367e-3
GO:0035247	peptidyl-arginine omega-N-methylation	6.941140e-3
GO:0042692	muscle cell differentiation	6.952920e-3
GO:0008015	blood circulation	7.040551e-3
GO:0046631	alpha-beta T cell activation	7.172168e-3
GO:0060327	cytoplasmic actin-based contraction involved in cell motility	7.206880e-3
GO:2000392	regulation of lamellipodium morphogenesis	7.206880e-3
GO:0070141	response to UV-A	7.220799e-3
GO:0043096	purine base salvage	7.252641e-3
GO:0060122	inner ear receptor stereocilium organization	7.564835e-3
GO:0007601	visual perception	7.590827e-3
GO:0009146	purine nucleoside triphosphate catabolic process	7.685684e-3
GO:0071712	ER-associated misfolded protein catabolic process	7.687787e-3
GO:0042048	olfactory behavior	7.687787e-3
GO:0007341	penetration of zona pellucida	7.806270e-3
GO:0071353	cellular response to interleukin-4	7.811435e-3
GO:0051891	positive regulation of cardioblast differentiation	7.817692e-3
GO:0090116	C-5 methylation of cytosine	7.881276e-3
GO:0051591	response to cAMP	7.928983e-3
GO:0042178	xenobiotic catabolic process	8.034476e-3
GO:0032007	negative regulation of TOR signaling cascade	8.034476e-3
GO:0007217	tachykinin receptor signaling pathway	8.034476e-3
GO:0032714	negative regulation of interleukin-5 production	8.070865e-3
GO:0060509	Type I pneumocyte differentiation	8.240309e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	8.240309e-3
GO:0097084	vascular smooth muscle cell development	8.262977e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	8.282999e-3
GO:0043380	regulation of memory T cell differentiation	8.553224e-3
GO:0022898	regulation of transmembrane transporter activity	8.642245e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	8.667909e-3
GO:0032227	negative regulation of synaptic transmission, dopaminergic	8.667909e-3
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	8.674720e-3
GO:0020027	hemoglobin metabolic process	8.738474e-3
GO:0007606	sensory perception of chemical stimulus	8.739794e-3
GO:0002639	positive regulation of immunoglobulin production	8.863976e-3
GO:0061088	regulation of sequestering of zinc ion	8.921459e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	8.921459e-3
GO:0032204	regulation of telomere maintenance	8.934733e-3
GO:0051154	negative regulation of striated muscle cell differentiation	9.039658e-3
GO:0002687	positive regulation of leukocyte migration	9.049045e-3
GO:0072215	regulation of metanephros development	9.064076e-3
GO:0071034	CUT catabolic process	9.169459e-3
GO:0042045	epithelial fluid transport	9.169459e-3
GO:0048842	positive regulation of axon extension involved in axon guidance	9.169459e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	9.181398e-3
GO:0045980	negative regulation of nucleotide metabolic process	9.185747e-3
GO:0048644	muscle organ morphogenesis	9.268694e-3
GO:0072282	metanephric nephron tubule morphogenesis	9.269932e-3
GO:0030335	positive regulation of cell migration	9.478881e-3
GO:0015872	dopamine transport	9.557701e-3
GO:0008631	induction of apoptosis by oxidative stress	9.612228e-3
GO:0060575	intestinal epithelial cell differentiation	9.624163e-3
GO:0048388	endosomal lumen acidification	9.795025e-3
GO:0045815	positive regulation of gene expression, epigenetic	9.831054e-3
GO:0006281	DNA repair	9.844064e-3
GO:0051593	response to folic acid	9.877688e-3
GO:0072239	metanephric glomerulus vasculature development	9.995332e-3
GO:0008366	axon ensheathment	1.012782e-2
GO:0051493	regulation of cytoskeleton organization	1.024462e-2