Novel motif:160

name:	motif160_AGCCGGTAACG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0034470	ncRNA processing	4.344377e-17
GO:0030433	ER-associated protein catabolic process	1.903049e-16
GO:0034660	ncRNA metabolic process	1.757141e-10
GO:0019048	virus-host interaction	4.008802e-10
GO:0043508	negative regulation of JUN kinase activity	1.933343e-9
GO:0006354	transcription elongation, DNA-dependent	2.176471e-9
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	6.555958e-9
GO:0006364	rRNA processing	6.606934e-9
GO:0016072	rRNA metabolic process	7.154769e-9
GO:0010511	regulation of phosphatidylinositol biosynthetic process	9.826669e-9
GO:0035461	vitamin transmembrane transport	1.770679e-8
GO:0008033	tRNA processing	3.642143e-8
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	5.850202e-8
GO:0071072	negative regulation of phospholipid biosynthetic process	6.386994e-8
GO:0031284	positive regulation of guanylate cyclase activity	6.456523e-8
GO:0006396	RNA processing	7.564045e-8
GO:0071071	regulation of phospholipid biosynthetic process	9.033158e-8
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.009792e-7
GO:0018205	peptidyl-lysine modification	1.086986e-7
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.561819e-7
GO:0042254	ribosome biogenesis	1.586050e-7
GO:0006298	mismatch repair	1.955566e-7
GO:0010498	proteasomal protein catabolic process	4.301472e-7
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	4.529381e-7
GO:0016570	histone modification	4.629980e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	6.113886e-7
GO:0006368	transcription elongation from RNA polymerase II promoter	6.583414e-7
GO:0010544	negative regulation of platelet activation	1.417576e-6
GO:0016569	covalent chromatin modification	1.640728e-6
GO:0016140	O-glycoside metabolic process	2.250466e-6
GO:0033326	cerebrospinal fluid secretion	2.335795e-6
GO:0045901	positive regulation of translational elongation	3.333557e-6
GO:0045905	positive regulation of translational termination	3.333557e-6
GO:0006452	translational frameshifting	3.333557e-6
GO:0001522	pseudouridine synthesis	3.367032e-6
GO:0061003	positive regulation of dendritic spine morphogenesis	3.399030e-6
GO:0097039	protein linear polyubiquitination	3.631034e-6
GO:0019087	transformation of host cell by virus	4.137137e-6
GO:0021986	habenula development	4.578735e-6
GO:2000009	negative regulation of protein localization at cell surface	4.702504e-6
GO:0016032	viral reproduction	5.250975e-6
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	8.703579e-6
GO:0070078	histone H3-R2 demethylation	9.245396e-6
GO:0070079	histone H4-R3 demethylation	9.245396e-6
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	9.245396e-6
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	1.068671e-5
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	1.200342e-5
GO:0008612	peptidyl-lysine modification to hypusine	1.251759e-5
GO:0070286	axonemal dynein complex assembly	1.307788e-5
GO:0051168	nuclear export	1.376310e-5
GO:0033148	positive regulation of estrogen receptor signaling pathway	1.382732e-5
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1.716073e-5
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1.835988e-5
GO:0006325	chromatin organization	1.873168e-5
GO:0034224	cellular response to zinc ion starvation	2.129747e-5
GO:0031282	regulation of guanylate cyclase activity	2.138600e-5
GO:0071934	thiamine transmembrane transport	2.433302e-5
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.532473e-5
GO:0006901	vesicle coating	2.680001e-5
GO:0010734	negative regulation of protein glutathionylation	2.926596e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.937991e-5
GO:0019060	intracellular transport of viral proteins in host cell	2.985483e-5
GO:0009450	gamma-aminobutyric acid catabolic process	3.288511e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	3.633406e-5
GO:0003290	atrial septum secundum morphogenesis	3.938880e-5
GO:0043084	penile erection	3.983361e-5
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	4.919487e-5
GO:0061157	mRNA destabilization	4.919487e-5
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	4.919487e-5
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	5.096477e-5
GO:0006473	protein acetylation	5.114891e-5
GO:0033146	regulation of estrogen receptor signaling pathway	5.141475e-5
GO:2000369	regulation of clathrin-mediated endocytosis	5.145084e-5
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.513963e-5
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.513963e-5
GO:0048194	Golgi vesicle budding	5.737569e-5
GO:0006900	membrane budding	5.774847e-5
GO:0008634	negative regulation of survival gene product expression	6.072824e-5
GO:0016568	chromatin modification	6.078076e-5
GO:0043543	protein acylation	6.188731e-5
GO:0016567	protein ubiquitination	6.192711e-5
GO:0021903	rostrocaudal neural tube patterning	7.138913e-5
GO:0000183	chromatin silencing at rDNA	7.709563e-5
GO:0016573	histone acetylation	8.011894e-5
GO:0006457	protein folding	8.033777e-5
GO:0006611	protein export from nucleus	8.147213e-5
GO:0070389	chaperone cofactor-dependent protein refolding	8.289244e-5
GO:0050434	positive regulation of viral transcription	8.650573e-5
GO:0018394	peptidyl-lysine acetylation	8.684696e-5
GO:0000212	meiotic spindle organization	8.748649e-5
GO:0006083	acetate metabolic process	8.903621e-5
GO:0070647	protein modification by small protein conjugation or removal	8.968715e-5
GO:0006348	chromatin silencing at telomere	9.248382e-5
GO:0006449	regulation of translational termination	9.574379e-5
GO:0042274	ribosomal small subunit biogenesis	9.801956e-5
GO:2000370	positive regulation of clathrin-mediated endocytosis	1.041115e-4
GO:0006475	internal protein amino acid acetylation	1.225560e-4
GO:0016142	O-glycoside catabolic process	1.243808e-4
GO:0014813	satellite cell commitment	1.243808e-4
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	1.243808e-4
GO:0032314	regulation of Rac GTPase activity	1.268487e-4
GO:0010823	negative regulation of mitochondrion organization	1.305064e-4
GO:0045007	depurination	1.314998e-4
GO:0009785	blue light signaling pathway	1.340090e-4
GO:0018393	internal peptidyl-lysine acetylation	1.450684e-4
GO:0046390	ribose phosphate biosynthetic process	1.599018e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.671597e-4
GO:0001661	conditioned taste aversion	1.745639e-4
GO:0018027	peptidyl-lysine dimethylation	1.798016e-4
GO:0046293	formaldehyde biosynthetic process	1.919381e-4
GO:0016246	RNA interference	2.055985e-4
GO:0015887	pantothenate transmembrane transport	2.164427e-4
GO:0015878	biotin transport	2.164427e-4
GO:0009650	UV protection	2.317901e-4
GO:0042273	ribosomal large subunit biogenesis	2.339493e-4
GO:0032205	negative regulation of telomere maintenance	2.440035e-4
GO:0008298	intracellular mRNA localization	2.646169e-4
GO:0072553	terminal button organization	2.649933e-4
GO:0061084	negative regulation of protein refolding	2.707333e-4
GO:2000210	positive regulation of anoikis	2.744373e-4
GO:0032042	mitochondrial DNA metabolic process	2.747731e-4
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	2.778688e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	2.807261e-4
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	2.838007e-4
GO:0090083	regulation of inclusion body assembly	2.934874e-4
GO:0014040	positive regulation of Schwann cell differentiation	2.973081e-4
GO:0046521	sphingoid catabolic process	3.116628e-4
GO:0045342	MHC class II biosynthetic process	3.116727e-4
GO:0070839	divalent metal ion export	3.116727e-4
GO:0006876	cellular cadmium ion homeostasis	3.116727e-4
GO:0043091	L-arginine import	3.116727e-4
GO:0032632	interleukin-3 production	3.116727e-4
GO:0015707	nitrite transport	3.116727e-4
GO:0072668	tubulin complex biogenesis	3.188230e-4
GO:0032446	protein modification by small protein conjugation	3.215859e-4
GO:0006489	dolichyl diphosphate biosynthetic process	3.836905e-4
GO:0000422	mitochondrion degradation	3.850407e-4
GO:0000076	DNA replication checkpoint	4.188816e-4
GO:0048205	COPI coating of Golgi vesicle	4.361467e-4
GO:0006438	valyl-tRNA aminoacylation	4.429707e-4
GO:0002309	T cell proliferation involved in immune response	4.626995e-4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4.954721e-4
GO:0070574	cadmium ion transmembrane transport	5.128622e-4
GO:0006515	misfolded or incompletely synthesized protein catabolic process	5.475703e-4
GO:0006419	alanyl-tRNA aminoacylation	5.560401e-4
GO:0090312	positive regulation of protein deacetylation	5.901193e-4
GO:0046782	regulation of viral transcription	5.911221e-4
GO:0032786	positive regulation of transcription elongation, DNA-dependent	5.971266e-4
GO:0031118	rRNA pseudouridine synthesis	6.075565e-4
GO:0070625	zymogen granule exocytosis	6.182249e-4
GO:0014895	smooth muscle hypertrophy	6.182249e-4
GO:0043048	dolichyl monophosphate biosynthetic process	6.182249e-4
GO:0003106	negative regulation of glomerular filtration by angiotensin	6.182249e-4
GO:0006742	NADP catabolic process	6.182249e-4
GO:0000460	maturation of 5.8S rRNA	6.211015e-4
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	6.232973e-4
GO:0030490	maturation of SSU-rRNA	6.363204e-4
GO:0097084	vascular smooth muscle cell development	6.464431e-4
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	6.514643e-4
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	6.514643e-4
GO:0046967	cytosol to ER transport	6.708293e-4
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	6.863684e-4
GO:0045720	negative regulation of integrin biosynthetic process	6.863684e-4
GO:0019102	male somatic sex determination	6.863684e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.104662e-4
GO:0017004	cytochrome complex assembly	7.587519e-4
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	7.677508e-4
GO:0010830	regulation of myotube differentiation	7.718177e-4
GO:0006448	regulation of translational elongation	8.000870e-4
GO:0035166	post-embryonic hemopoiesis	8.018869e-4
GO:0007023	post-chaperonin tubulin folding pathway	8.018869e-4
GO:0006399	tRNA metabolic process	8.022868e-4
GO:0033590	response to cobalamin	8.671467e-4
GO:0006117	acetaldehyde metabolic process	8.671467e-4
GO:2000465	regulation of glycogen (starch) synthase activity	8.684473e-4
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	9.642882e-4
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	9.642882e-4
GO:0031065	positive regulation of histone deacetylation	9.843179e-4
GO:0006264	mitochondrial DNA replication	9.920338e-4
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	9.933368e-4
GO:0043248	proteasome assembly	1.006660e-3
GO:0006313	transposition, DNA-mediated	1.028666e-3
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1.031211e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	1.076697e-3
GO:0002456	T cell mediated immunity	1.116180e-3
GO:0071044	histone mRNA catabolic process	1.164516e-3
GO:0071218	cellular response to misfolded protein	1.175580e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	1.187988e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	1.194815e-3
GO:0045065	cytotoxic T cell differentiation	1.194815e-3
GO:0021796	cerebral cortex regionalization	1.194815e-3
GO:0006097	glyoxylate cycle	1.194815e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1.210838e-3
GO:0060286	flagellar cell motility	1.210838e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	1.210838e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	1.210838e-3
GO:0006406	mRNA export from nucleus	1.215414e-3
GO:0018993	somatic sex determination	1.234357e-3
GO:0000154	rRNA modification	1.234357e-3
GO:0042375	quinone cofactor metabolic process	1.239740e-3
GO:2000209	regulation of anoikis	1.267463e-3
GO:0022613	ribonucleoprotein complex biogenesis	1.324647e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	1.350855e-3
GO:0018344	protein geranylgeranylation	1.350855e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	1.350855e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	1.350945e-3
GO:0006491	N-glycan processing	1.359317e-3
GO:0008078	mesodermal cell migration	1.376241e-3
GO:0090324	negative regulation of oxidative phosphorylation	1.446631e-3
GO:0010255	glucose mediated signaling pathway	1.446631e-3
GO:0009436	glyoxylate catabolic process	1.446631e-3
GO:0009912	auditory receptor cell fate commitment	1.457910e-3
GO:0009405	pathogenesis	1.496952e-3
GO:0009155	purine deoxyribonucleotide catabolic process	1.522876e-3
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	1.534147e-3
GO:0019478	D-amino acid catabolic process	1.571393e-3
GO:0070845	polyubiquitinated misfolded protein transport	1.600317e-3
GO:0002523	leukocyte migration involved in inflammatory response	1.645704e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.716938e-3
GO:0030422	production of siRNA involved in RNA interference	1.766091e-3
GO:0009637	response to blue light	1.766091e-3
GO:0070904	transepithelial L-ascorbic acid transport	1.807065e-3
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.865281e-3
GO:0034968	histone lysine methylation	1.999303e-3
GO:0003062	regulation of heart rate by chemical signal	2.074139e-3
GO:0048050	post-embryonic eye morphogenesis	2.122064e-3
GO:0070535	histone H2A K63-linked ubiquitination	2.156682e-3
GO:0002513	tolerance induction to self antigen	2.166249e-3
GO:0034509	centromeric core chromatin assembly	2.168882e-3
GO:0030393	fructoselysine metabolic process	2.168882e-3
GO:0048199	vesicle targeting, to, from or within Golgi	2.274124e-3
GO:0015822	ornithine transport	2.280534e-3
GO:0042053	regulation of dopamine metabolic process	2.304207e-3
GO:0045793	positive regulation of cell size	2.318960e-3
GO:0001309	age-dependent telomere shortening	2.323675e-3
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication	2.323675e-3
GO:0003285	septum secundum development	2.371610e-3
GO:0060178	regulation of exocyst localization	2.383755e-3
GO:0001928	regulation of exocyst assembly	2.383755e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.383755e-3
GO:0009303	rRNA transcription	2.452059e-3
GO:0071415	cellular response to purine-containing compound	2.519925e-3
GO:0016180	snRNA processing	2.539904e-3
GO:0070255	regulation of mucus secretion	2.616263e-3
GO:0000072	M phase specific microtubule process	2.740040e-3
GO:0046784	intronless viral mRNA export from host nucleus	2.762594e-3
GO:0060711	labyrinthine layer development	2.844084e-3
GO:0021932	hindbrain radial glia guided cell migration	2.897268e-3
GO:0090085	regulation of protein deubiquitination	2.910869e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	2.930135e-3
GO:0000066	mitochondrial ornithine transport	2.938384e-3
GO:0060586	multicellular organismal iron ion homeostasis	3.122111e-3
GO:0018026	peptidyl-lysine monomethylation	3.190341e-3
GO:0071421	manganese ion transmembrane transport	3.212097e-3
GO:0019941	modification-dependent protein catabolic process	3.315647e-3
GO:0006362	transcription elongation from RNA polymerase I promoter	3.330535e-3
GO:0050861	positive regulation of B cell receptor signaling pathway	3.331248e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3.331248e-3
GO:0060464	lung lobe formation	3.331248e-3
GO:0043456	regulation of pentose-phosphate shunt	3.385899e-3
GO:0015761	mannose transport	3.385899e-3
GO:0042069	regulation of catecholamine metabolic process	3.395810e-3
GO:0032792	negative regulation of CREB transcription factor activity	3.450385e-3
GO:0070534	protein K63-linked ubiquitination	3.462204e-3
GO:0006290	pyrimidine dimer repair	3.463940e-3
GO:0050765	negative regulation of phagocytosis	3.570860e-3
GO:0010701	positive regulation of norepinephrine secretion	3.579049e-3
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	3.579049e-3
GO:0071712	ER-associated misfolded protein catabolic process	3.591972e-3
GO:0051028	mRNA transport	3.693387e-3
GO:0060263	regulation of respiratory burst	3.708808e-3
GO:0006511	ubiquitin-dependent protein catabolic process	3.738806e-3
GO:0008637	apoptotic mitochondrial changes	3.746099e-3
GO:0090084	negative regulation of inclusion body assembly	3.755493e-3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	3.917707e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3.945835e-3
GO:0009451	RNA modification	3.952007e-3
GO:0010430	fatty acid omega-oxidation	3.983493e-3
GO:0090086	negative regulation of protein deubiquitination	3.983493e-3
GO:0043267	negative regulation of potassium ion transport	4.234025e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.311077e-3
GO:0045116	protein neddylation	4.377648e-3
GO:0002921	negative regulation of humoral immune response	4.397508e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	4.518781e-3
GO:0021526	medial motor column neuron differentiation	4.518781e-3
GO:0043632	modification-dependent macromolecule catabolic process	4.567698e-3
GO:0021562	vestibulocochlear nerve development	4.593056e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	4.602169e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	4.637662e-3
GO:0050689	negative regulation of defense response to virus by host	4.647009e-3
GO:0008636	activation of caspase activity by protein phosphorylation	4.647009e-3
GO:0035409	histone H3-Y41 phosphorylation	4.647009e-3
GO:0006914	autophagy	4.650099e-3
GO:0006903	vesicle targeting	4.679749e-3
GO:0070170	regulation of tooth mineralization	4.702702e-3
GO:0060535	trachea cartilage morphogenesis	4.751699e-3
GO:0071542	dopaminergic neuron differentiation	4.764497e-3
GO:0016073	snRNA metabolic process	4.848721e-3
GO:0060674	placenta blood vessel development	5.045278e-3
GO:0050687	negative regulation of defense response to virus	5.071678e-3
GO:0071480	cellular response to gamma radiation	5.128372e-3
GO:0002082	regulation of oxidative phosphorylation	5.196945e-3
GO:0065002	intracellular protein transmembrane transport	5.280389e-3
GO:0043628	ncRNA 3'-end processing	5.280389e-3
GO:0010225	response to UV-C	5.481551e-3
GO:0010025	wax biosynthetic process	5.565238e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	5.596225e-3
GO:0002121	inter-male aggressive behavior	5.685106e-3
GO:0009304	tRNA transcription	5.859545e-3
GO:0016137	glycoside metabolic process	5.877795e-3
GO:0006405	RNA export from nucleus	6.238625e-3
GO:0006400	tRNA modification	6.372999e-3
GO:0019532	oxalate transport	6.416779e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	6.426724e-3
GO:0006281	DNA repair	6.476238e-3
GO:0016571	histone methylation	6.489606e-3
GO:0046732	active induction of host immune response by virus	6.514198e-3
GO:0051567	histone H3-K9 methylation	6.525263e-3
GO:0009262	deoxyribonucleotide metabolic process	6.713035e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	6.811346e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	6.811977e-3
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	6.923622e-3
GO:0060669	embryonic placenta morphogenesis	6.967684e-3
GO:0060242	contact inhibition	6.973185e-3
GO:0043173	nucleotide salvage	6.973185e-3
GO:0008334	histone mRNA metabolic process	7.073795e-3
GO:0042418	epinephrine biosynthetic process	7.090356e-3
GO:0042780	tRNA 3'-end processing	7.090356e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	7.090356e-3
GO:0006713	glucocorticoid catabolic process	7.090356e-3
GO:0006585	dopamine biosynthetic process from tyrosine	7.090356e-3
GO:0021771	lateral geniculate nucleus development	7.090356e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	7.383969e-3
GO:0035967	cellular response to topologically incorrect protein	7.443668e-3
GO:0010866	regulation of triglyceride biosynthetic process	7.460582e-3
GO:0031536	positive regulation of exit from mitosis	7.590260e-3
GO:2001014	regulation of skeletal muscle cell differentiation	7.684812e-3
GO:0015993	molecular hydrogen transport	7.735274e-3
GO:0032976	release of matrix enzymes from mitochondria	7.833348e-3
GO:0046674	induction of retinal programmed cell death	7.833348e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	7.833348e-3
GO:0030214	hyaluronan catabolic process	7.833348e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	7.833348e-3
GO:0021764	amygdala development	7.833348e-3
GO:0002352	B cell negative selection	7.833348e-3
GO:0001777	T cell homeostatic proliferation	7.833348e-3
GO:0001579	medium-chain fatty acid transport	7.833348e-3
GO:0030854	positive regulation of granulocyte differentiation	7.859648e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	8.044339e-3
GO:0006463	steroid hormone receptor complex assembly	8.044339e-3
GO:0032099	negative regulation of appetite	8.182828e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	8.269579e-3
GO:0070682	proteasome regulatory particle assembly	8.269579e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	8.298431e-3
GO:0019408	dolichol biosynthetic process	8.429528e-3
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	8.459982e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	8.518700e-3
GO:0046833	positive regulation of RNA export from nucleus	8.518700e-3
GO:0006283	transcription-coupled nucleotide-excision repair	8.545553e-3
GO:0035966	response to topologically incorrect protein	8.560258e-3
GO:0042074	cell migration involved in gastrulation	8.645680e-3
GO:0010543	regulation of platelet activation	8.720153e-3
GO:0030917	midbrain-hindbrain boundary development	8.847144e-3
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	8.905286e-3
GO:0046292	formaldehyde metabolic process	8.990113e-3
GO:0006984	ER-nucleus signaling pathway	8.990515e-3
GO:0008535	respiratory chain complex IV assembly	9.385236e-3
GO:0042354	L-fucose metabolic process	9.387117e-3
GO:0034214	protein hexamerization	9.608684e-3
GO:0006004	fucose metabolic process	9.659156e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	9.673871e-3
GO:0002149	hypochlorous acid biosynthetic process	9.702666e-3
GO:0032851	positive regulation of Rab GTPase activity	9.761752e-3
GO:0016139	glycoside catabolic process	1.006880e-2
GO:0014816	satellite cell differentiation	1.010874e-2
GO:0009263	deoxyribonucleotide biosynthetic process	1.016056e-2
GO:0030851	granulocyte differentiation	1.022349e-2
GO:0072385	minus-end-directed organelle transport along microtubule	1.028448e-2
GO:0048102	autophagic cell death	1.031110e-2
GO:0007051	spindle organization	1.032990e-2
GO:0060712	spongiotrophoblast layer development	1.034895e-2
GO:0060708	spongiotrophoblast differentiation	1.054840e-2
GO:0003149	membranous septum morphogenesis	1.076737e-2
GO:0051583	dopamine uptake	1.076737e-2
GO:0060574	intestinal epithelial cell maturation	1.101360e-2
GO:0035425	autocrine signaling	1.101360e-2
GO:0021501	prechordal plate formation	1.101360e-2
GO:0021547	midbrain-hindbrain boundary initiation	1.101360e-2
GO:0009448	gamma-aminobutyric acid metabolic process	1.116003e-2
GO:0002293	alpha-beta T cell differentiation involved in immune response	1.128634e-2
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	1.130157e-2
GO:0035054	embryonic heart tube anterior/posterior pattern specification	1.140066e-2
GO:0046100	hypoxanthine metabolic process	1.142998e-2
GO:0042093	T-helper cell differentiation	1.156348e-2
GO:2000272	negative regulation of receptor activity	1.169096e-2
GO:0045090	retroviral genome replication	1.180107e-2
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.180107e-2
GO:0043973	histone H3-K4 acetylation	1.180107e-2
GO:0060003	copper ion export	1.180107e-2
GO:0015677	copper ion import	1.180107e-2
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.180107e-2
GO:0006408	snRNA export from nucleus	1.180107e-2
GO:0006913	nucleocytoplasmic transport	1.194632e-2
GO:0021535	cell migration in hindbrain	1.200550e-2
GO:0070734	histone H3-K27 methylation	1.224462e-2
GO:0006825	copper ion transport	1.233919e-2
GO:0018022	peptidyl-lysine methylation	1.251291e-2
GO:0045776	negative regulation of blood pressure	1.251765e-2
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.269888e-2
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.273408e-2
GO:0010760	negative regulation of macrophage chemotaxis	1.273408e-2
GO:0045725	positive regulation of glycogen biosynthetic process	1.291314e-2
GO:0052314	phytoalexin metabolic process	1.306300e-2
GO:0034551	mitochondrial respiratory chain complex III assembly	1.306300e-2
GO:0060999	positive regulation of dendritic spine development	1.321710e-2
GO:0008156	negative regulation of DNA replication	1.324248e-2
GO:0060561	apoptosis involved in morphogenesis	1.326499e-2
GO:0009312	oligosaccharide biosynthetic process	1.328754e-2
GO:0006479	protein methylation	1.333132e-2
GO:0015917	aminophospholipid transport	1.344075e-2
GO:0060084	synaptic transmission involved in micturition	1.349749e-2
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.367588e-2
GO:0009817	defense response to fungus, incompatible interaction	1.367588e-2
GO:0032261	purine nucleotide salvage	1.369111e-2
GO:0042481	regulation of odontogenesis	1.411258e-2
GO:0000022	mitotic spindle elongation	1.411600e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.413809e-2
GO:0046416	D-amino acid metabolic process	1.413809e-2
GO:0006384	transcription initiation from RNA polymerase III promoter	1.413809e-2
GO:0003327	type B pancreatic cell fate commitment	1.413809e-2
GO:0046730	induction of host immune response by virus	1.440430e-2
GO:0016226	iron-sulfur cluster assembly	1.445466e-2
GO:0051036	regulation of endosome size	1.455067e-2
GO:0010523	negative regulation of calcium ion transport into cytosol	1.458872e-2
GO:0032096	negative regulation of response to food	1.470272e-2
GO:0090241	negative regulation of histone H4 acetylation	1.511209e-2
GO:0018342	protein prenylation	1.511209e-2
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	1.511209e-2
GO:0006403	RNA localization	1.515900e-2
GO:0090311	regulation of protein deacetylation	1.535831e-2
GO:0042373	vitamin K metabolic process	1.563800e-2
GO:0002069	columnar/cuboidal epithelial cell maturation	1.563800e-2
GO:0048268	clathrin coat assembly	1.567426e-2
GO:2000978	negative regulation of forebrain neuron differentiation	1.574964e-2
GO:2000227	negative regulation of pancreatic A cell differentiation	1.574964e-2
GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	1.574964e-2
GO:0046331	lateral inhibition	1.574964e-2
GO:0019693	ribose phosphate metabolic process	1.578348e-2
GO:0002027	regulation of heart rate	1.579693e-2
GO:0021557	oculomotor nerve development	1.591893e-2
GO:0006285	base-excision repair, AP site formation	1.603008e-2
GO:0061303	cornea development in camera-type eye	1.603008e-2
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.627459e-2
GO:0001302	replicative cell aging	1.639909e-2
GO:0071843	cellular component biogenesis at cellular level	1.642529e-2
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.653115e-2
GO:0050774	negative regulation of dendrite morphogenesis	1.663550e-2
GO:0060670	branching involved in embryonic placenta morphogenesis	1.664863e-2
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.667065e-2
GO:0002827	positive regulation of T-helper 1 type immune response	1.675072e-2
GO:0070317	negative regulation of G0 to G1 transition	1.675610e-2
GO:0051754	meiotic sister chromatid cohesion, centromeric	1.675610e-2
GO:0006747	FAD biosynthetic process	1.675610e-2
GO:0043610	regulation of carbohydrate utilization	1.675610e-2
GO:0046605	regulation of centrosome cycle	1.688011e-2
GO:0051084	'de novo' posttranslational protein folding	1.712176e-2
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.717054e-2
GO:2000744	positive regulation of anterior head development	1.743469e-2
GO:0042026	protein refolding	1.760442e-2
GO:0044088	regulation of vacuole organization	1.762771e-2
GO:0042109	lymphotoxin A biosynthetic process	1.762771e-2
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.762771e-2
GO:0060220	camera-type eye photoreceptor cell fate commitment	1.769593e-2
GO:0048074	negative regulation of eye pigmentation	1.769593e-2
GO:0046670	positive regulation of retinal cell programmed cell death	1.769593e-2
GO:0002534	cytokine production involved in inflammatory response	1.769593e-2
GO:0034276	kynurenic acid biosynthetic process	1.769593e-2
GO:0045351	type I interferon biosynthetic process	1.783912e-2
GO:0050855	regulation of B cell receptor signaling pathway	1.786034e-2
GO:0032049	cardiolipin biosynthetic process	1.786034e-2
GO:0035873	lactate transmembrane transport	1.786034e-2
GO:0060575	intestinal epithelial cell differentiation	1.820275e-2
GO:0051788	response to misfolded protein	1.820937e-2
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.824515e-2
GO:0060534	trachea cartilage development	1.833330e-2
GO:0019322	pentose biosynthetic process	1.833330e-2
GO:0021558	trochlear nerve development	1.834805e-2
GO:2000114	regulation of establishment of cell polarity	1.853011e-2
GO:0042407	cristae formation	1.899720e-2
GO:0046690	response to tellurium ion	1.899720e-2
GO:0031627	telomeric loop formation	1.899720e-2
GO:0060086	circadian temperature homeostasis	1.899720e-2
GO:0051791	medium-chain fatty acid metabolic process	1.899720e-2
GO:0031119	tRNA pseudouridine synthesis	1.899720e-2
GO:0006231	dTMP biosynthetic process	1.899720e-2
GO:0006741	NADP biosynthetic process	1.899720e-2
GO:0019088	immortalization of host cell by virus	1.899720e-2
GO:0009645	response to low light intensity stimulus	1.899720e-2
GO:0070918	production of small RNA involved in gene silencing by RNA	1.915049e-2
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.918720e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016072	rRNA metabolic process	4.910642e-10
GO:0070925	organelle assembly	1.954869e-9
GO:0042254	ribosome biogenesis	2.741363e-9
GO:0006364	rRNA processing	1.094924e-8
GO:0007264	small GTPase mediated signal transduction	7.018086e-8
GO:0035307	positive regulation of protein dephosphorylation	1.823233e-7
GO:0035306	positive regulation of dephosphorylation	2.302616e-7
GO:0000183	chromatin silencing at rDNA	2.935813e-7
GO:0015876	acetyl-CoA transport	3.145851e-7
GO:0006427	histidyl-tRNA aminoacylation	3.295844e-7
GO:0033239	negative regulation of cellular amine metabolic process	6.315360e-7
GO:0018023	peptidyl-lysine trimethylation	6.355560e-7
GO:0042053	regulation of dopamine metabolic process	7.260367e-7
GO:0048332	mesoderm morphogenesis	1.235739e-6
GO:0022613	ribonucleoprotein complex biogenesis	2.231676e-6
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.363181e-6
GO:0043314	negative regulation of neutrophil degranulation	2.744861e-6
GO:0006438	valyl-tRNA aminoacylation	2.930129e-6
GO:0042069	regulation of catecholamine metabolic process	3.440931e-6
GO:0044260	cellular macromolecule metabolic process	3.587231e-6
GO:0035441	cell migration involved in vasculogenesis	3.610838e-6
GO:0043653	mitochondrial fragmentation involved in apoptosis	3.610838e-6
GO:0015780	nucleotide-sugar transport	4.442713e-6
GO:0006188	IMP biosynthetic process	6.261475e-6
GO:0016574	histone ubiquitination	6.282367e-6
GO:0006401	RNA catabolic process	6.305005e-6
GO:0043301	negative regulation of leukocyte degranulation	7.192517e-6
GO:0031167	rRNA methylation	8.301446e-6
GO:0031577	spindle checkpoint	9.027751e-6
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	9.533266e-6
GO:0045875	negative regulation of sister chromatid cohesion	9.683002e-6
GO:0009113	purine base biosynthetic process	1.202324e-5
GO:0033238	regulation of cellular amine metabolic process	1.252858e-5
GO:0035372	protein localization to microtubule	1.345586e-5
GO:0000045	autophagic vacuole assembly	1.426366e-5
GO:0006342	chromatin silencing	1.468661e-5
GO:0031023	microtubule organizing center organization	1.854595e-5
GO:0001840	neural plate development	2.070109e-5
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	2.202414e-5
GO:0071843	cellular component biogenesis at cellular level	2.248980e-5
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	2.344851e-5
GO:0034508	centromere complex assembly	2.698703e-5
GO:0043313	regulation of neutrophil degranulation	3.087460e-5
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3.174276e-5
GO:0042147	retrograde transport, endosome to Golgi	4.145271e-5
GO:0045814	negative regulation of gene expression, epigenetic	4.165298e-5
GO:0000154	rRNA modification	4.459486e-5
GO:0016075	rRNA catabolic process	4.549605e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	4.585241e-5
GO:0035562	negative regulation of chromatin binding	4.585241e-5
GO:0030970	retrograde protein transport, ER to cytosol	5.563568e-5
GO:0007098	centrosome cycle	5.573379e-5
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	6.031532e-5
GO:0016191	synaptic vesicle uncoating	6.031532e-5
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	6.284224e-5
GO:0060299	negative regulation of sarcomere organization	6.284224e-5
GO:0034660	ncRNA metabolic process	6.314684e-5
GO:0050775	positive regulation of dendrite morphogenesis	7.205798e-5
GO:0043624	cellular protein complex disassembly	7.765637e-5
GO:0071034	CUT catabolic process	8.202182e-5
GO:0043241	protein complex disassembly	8.212250e-5
GO:0071173	spindle assembly checkpoint	8.473939e-5
GO:0035304	regulation of protein dephosphorylation	9.511029e-5
GO:0017148	negative regulation of translation	9.846985e-5
GO:0034470	ncRNA processing	1.098795e-4
GO:0050668	positive regulation of homocysteine metabolic process	1.157541e-4
GO:0045963	negative regulation of dopamine metabolic process	1.157541e-4
GO:0006402	mRNA catabolic process	1.258404e-4
GO:0001707	mesoderm formation	1.298838e-4
GO:0018205	peptidyl-lysine modification	1.352181e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.360171e-4
GO:0051176	positive regulation of sulfur metabolic process	1.365167e-4
GO:0016559	peroxisome fission	1.441022e-4
GO:0034661	ncRNA catabolic process	1.490065e-4
GO:0070079	histone H4-R3 demethylation	1.512971e-4
GO:0070078	histone H3-R2 demethylation	1.512971e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.512971e-4
GO:0046605	regulation of centrosome cycle	1.606366e-4
GO:0051297	centrosome organization	1.661828e-4
GO:0046498	S-adenosylhomocysteine metabolic process	1.678572e-4
GO:0023019	signal transduction involved in regulation of gene expression	1.702385e-4
GO:0000910	cytokinesis	1.871607e-4
GO:0006184	GTP catabolic process	1.882751e-4
GO:0080164	regulation of nitric oxide metabolic process	1.977643e-4
GO:0046112	nucleobase biosynthetic process	1.980403e-4
GO:0018283	iron incorporation into metallo-sulfur cluster	2.207977e-4
GO:2000300	regulation of synaptic vesicle exocytosis	2.213905e-4
GO:0006189	'de novo' IMP biosynthetic process	2.267829e-4
GO:0046039	GTP metabolic process	2.317894e-4
GO:0090304	nucleic acid metabolic process	2.322565e-4
GO:0022411	cellular component disassembly	2.386070e-4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	2.430789e-4
GO:0006396	RNA processing	2.490834e-4
GO:0071845	cellular component disassembly at cellular level	2.546125e-4
GO:0022038	corpus callosum development	2.644859e-4
GO:0034227	tRNA thio-modification	2.889349e-4
GO:0046599	regulation of centriole replication	2.926407e-4
GO:0032984	macromolecular complex disassembly	2.935256e-4
GO:0034623	cellular macromolecular complex disassembly	3.038429e-4
GO:0016236	macroautophagy	3.101682e-4
GO:0051301	cell division	3.307537e-4
GO:0006886	intracellular protein transport	3.315288e-4
GO:0002098	tRNA wobble uridine modification	3.381917e-4
GO:0006481	C-terminal protein methylation	3.509590e-4
GO:0051586	positive regulation of dopamine uptake	3.551433e-4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.653558e-4
GO:0007099	centriole replication	3.751220e-4
GO:0006499	N-terminal protein myristoylation	3.809102e-4
GO:0002730	regulation of dendritic cell cytokine production	3.809102e-4
GO:0001839	neural plate morphogenesis	3.869967e-4
GO:0035494	SNARE complex disassembly	4.000603e-4
GO:0043538	regulation of actin phosphorylation	4.000603e-4
GO:0010807	regulation of synaptic vesicle priming	4.000603e-4
GO:0060696	regulation of phospholipid catabolic process	4.180560e-4
GO:0035024	negative regulation of Rho protein signal transduction	4.282293e-4
GO:0046499	S-adenosylmethioninamine metabolic process	4.593985e-4
GO:0014912	negative regulation of smooth muscle cell migration	4.660978e-4
GO:0007183	SMAD protein complex assembly	4.702159e-4
GO:0018022	peptidyl-lysine methylation	4.825342e-4
GO:0018105	peptidyl-serine phosphorylation	4.831587e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	4.885782e-4
GO:0034067	protein localization in Golgi apparatus	4.944364e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	4.952900e-4
GO:0006391	transcription initiation from mitochondrial promoter	5.279468e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.379148e-4
GO:0007498	mesoderm development	5.521692e-4
GO:0031508	centromeric heterochromatin formation	5.661088e-4
GO:0071174	mitotic cell cycle spindle checkpoint	6.169155e-4
GO:0000266	mitochondrial fission	6.257016e-4
GO:0016082	synaptic vesicle priming	6.349012e-4
GO:0006415	translational termination	6.349012e-4
GO:0060005	vestibular reflex	6.769273e-4
GO:0010467	gene expression	7.156470e-4
GO:0061302	smooth muscle cell-matrix adhesion	7.536724e-4
GO:0033566	gamma-tubulin complex localization	7.536724e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.660335e-4
GO:0051182	coenzyme transport	7.683182e-4
GO:0006658	phosphatidylserine metabolic process	7.752565e-4
GO:0061084	negative regulation of protein refolding	7.910801e-4
GO:0045759	negative regulation of action potential	7.910801e-4
GO:0090231	regulation of spindle checkpoint	8.257482e-4
GO:0008272	sulfate transport	8.286137e-4
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	8.886154e-4
GO:0009817	defense response to fungus, incompatible interaction	8.886154e-4
GO:0010722	regulation of ferrochelatase activity	8.886154e-4
GO:0070535	histone H2A K63-linked ubiquitination	8.950274e-4
GO:0016142	O-glycoside catabolic process	8.950274e-4
GO:0008104	protein localization	9.465319e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	9.609363e-4
GO:0072355	histone H3-T3 phosphorylation	9.620903e-4
GO:0033314	mitotic cell cycle DNA replication checkpoint	9.620903e-4
GO:0001579	medium-chain fatty acid transport	9.620903e-4
GO:0016070	RNA metabolic process	9.703186e-4
GO:0061153	trachea gland development	1.001590e-3
GO:0048069	eye pigmentation	1.001590e-3
GO:0019049	evasion of host defenses by virus	1.029891e-3
GO:0010936	negative regulation of macrophage cytokine production	1.029891e-3
GO:0046782	regulation of viral transcription	1.033391e-3
GO:0006779	porphyrin-containing compound biosynthetic process	1.042221e-3
GO:0050434	positive regulation of viral transcription	1.043877e-3
GO:0071895	odontoblast differentiation	1.095451e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	1.134471e-3
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	1.164564e-3
GO:0060579	ventral spinal cord interneuron fate commitment	1.165206e-3
GO:0048285	organelle fission	1.172172e-3
GO:0045792	negative regulation of cell size	1.268160e-3
GO:0032319	regulation of Rho GTPase activity	1.292335e-3
GO:0060492	lung induction	1.309538e-3
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	1.309538e-3
GO:0070389	chaperone cofactor-dependent protein refolding	1.331310e-3
GO:0022007	convergent extension involved in neural plate elongation	1.360703e-3
GO:0007051	spindle organization	1.416568e-3
GO:0021570	rhombomere 4 development	1.418466e-3
GO:0021861	forebrain radial glial cell differentiation	1.445355e-3
GO:0006412	translation	1.546631e-3
GO:0046329	negative regulation of JNK cascade	1.557358e-3
GO:0043201	response to leucine	1.585660e-3
GO:0030719	P granule organization	1.585660e-3
GO:0006891	intra-Golgi vesicle-mediated transport	1.586262e-3
GO:0044265	cellular macromolecule catabolic process	1.597101e-3
GO:0000042	protein targeting to Golgi	1.612562e-3
GO:0015031	protein transport	1.617661e-3
GO:0032077	positive regulation of deoxyribonuclease activity	1.667833e-3
GO:0071711	basement membrane organization	1.673122e-3
GO:0032530	regulation of microvillus organization	1.730143e-3
GO:0002074	extraocular skeletal muscle development	1.730143e-3
GO:0021571	rhombomere 5 development	1.773801e-3
GO:0009057	macromolecule catabolic process	1.776575e-3
GO:0030223	neutrophil differentiation	1.932548e-3
GO:0061381	cell migration in diencephalon	1.952878e-3
GO:0061379	inferior colliculus development	1.952878e-3
GO:0021855	hypothalamus cell migration	1.952878e-3
GO:0061374	mammillothalamic axonal tract development	1.952878e-3
GO:0008637	apoptotic mitochondrial changes	1.986221e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	2.070877e-3
GO:0006139	nucleobase-containing compound metabolic process	2.071860e-3
GO:0071294	cellular response to zinc ion	2.144036e-3
GO:0033590	response to cobalamin	2.165720e-3
GO:0006601	creatine biosynthetic process	2.165720e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	2.266262e-3
GO:0045175	basal protein localization	2.266262e-3
GO:0031584	activation of phospholipase D activity	2.285305e-3
GO:0031055	chromatin remodeling at centromere	2.285305e-3
GO:0006829	zinc ion transport	2.348511e-3
GO:0002534	cytokine production involved in inflammatory response	2.431501e-3
GO:0034276	kynurenic acid biosynthetic process	2.431501e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	2.431501e-3
GO:0035115	embryonic forelimb morphogenesis	2.561071e-3
GO:0034379	very-low-density lipoprotein particle assembly	2.569875e-3
GO:0010822	positive regulation of mitochondrion organization	2.572030e-3
GO:0033522	histone H2A ubiquitination	2.573102e-3
GO:0007266	Rho protein signal transduction	2.614280e-3
GO:0006493	protein O-linked glycosylation	2.715498e-3
GO:0051298	centrosome duplication	2.743517e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	2.743517e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	2.759526e-3
GO:0009264	deoxyribonucleotide catabolic process	2.759526e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	2.869436e-3
GO:0043632	modification-dependent macromolecule catabolic process	2.883008e-3
GO:0019941	modification-dependent protein catabolic process	3.011613e-3
GO:0032321	positive regulation of Rho GTPase activity	3.055720e-3
GO:0006511	ubiquitin-dependent protein catabolic process	3.114854e-3
GO:0021569	rhombomere 3 development	3.147225e-3
GO:0060367	sagittal suture morphogenesis	3.183655e-3
GO:0060873	anterior semicircular canal development	3.183655e-3
GO:0070242	thymocyte apoptosis	3.183655e-3
GO:0060875	lateral semicircular canal development	3.183655e-3
GO:0060366	lambdoid suture morphogenesis	3.183655e-3
GO:0051382	kinetochore assembly	3.183655e-3
GO:0035520	monoubiquitinated protein deubiquitination	3.183655e-3
GO:0022018	lateral ganglionic eminence cell proliferation	3.183655e-3
GO:0035553	oxidative single-stranded RNA demethylation	3.183655e-3
GO:0048340	paraxial mesoderm morphogenesis	3.303039e-3
GO:0071480	cellular response to gamma radiation	3.354975e-3
GO:0009262	deoxyribonucleotide metabolic process	3.433572e-3
GO:0060364	frontal suture morphogenesis	3.440003e-3
GO:0010824	regulation of centrosome duplication	3.440003e-3
GO:0060461	right lung morphogenesis	3.524846e-3
GO:0090131	mesenchyme migration	3.524846e-3
GO:0014822	detection of wounding	3.524846e-3
GO:0060446	branching involved in open tracheal system development	3.524846e-3
GO:0048613	embryonic ectodermal digestive tract morphogenesis	3.524846e-3
GO:0042492	gamma-delta T cell differentiation	3.524846e-3
GO:0048371	lateral mesodermal cell differentiation	3.524846e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	3.569998e-3
GO:0018364	peptidyl-glutamine methylation	3.569998e-3
GO:0070831	basement membrane assembly	3.569998e-3
GO:0016569	covalent chromatin modification	3.632963e-3
GO:0010452	histone H3-K36 methylation	3.670006e-3
GO:0021986	habenula development	3.677297e-3
GO:0040015	negative regulation of multicellular organism growth	3.741796e-3
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	3.820476e-3
GO:0032922	circadian regulation of gene expression	3.822221e-3
GO:0008078	mesodermal cell migration	3.825777e-3
GO:0008654	phospholipid biosynthetic process	3.838273e-3
GO:0071168	protein localization to chromatin	3.854017e-3
GO:0051299	centrosome separation	3.854017e-3
GO:0046426	negative regulation of JAK-STAT cascade	4.175754e-3
GO:0070534	protein K63-linked ubiquitination	4.400454e-3
GO:0002829	negative regulation of type 2 immune response	4.478258e-3
GO:0043949	regulation of cAMP-mediated signaling	4.549754e-3
GO:0010950	positive regulation of endopeptidase activity	4.556355e-3
GO:0021542	dentate gyrus development	4.605938e-3
GO:0014819	regulation of skeletal muscle contraction	4.844314e-3
GO:0008612	peptidyl-lysine modification to hypusine	4.845381e-3
GO:0014910	regulation of smooth muscle cell migration	4.860839e-3
GO:0035404	histone-serine phosphorylation	4.914970e-3
GO:0060236	regulation of mitotic spindle organization	4.949321e-3
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	4.949321e-3
GO:0006778	porphyrin-containing compound metabolic process	4.982940e-3
GO:0002719	negative regulation of cytokine production involved in immune response	4.984129e-3
GO:0014745	negative regulation of muscle adaptation	5.008155e-3
GO:0043610	regulation of carbohydrate utilization	5.140088e-3
GO:2000781	positive regulation of double-strand break repair	5.140088e-3
GO:0070922	small RNA loading onto RISC	5.140088e-3
GO:0019047	provirus integration	5.140088e-3
GO:0016140	O-glycoside metabolic process	5.140088e-3
GO:0048741	skeletal muscle fiber development	5.192851e-3
GO:0030219	megakaryocyte differentiation	5.264386e-3
GO:0045184	establishment of protein localization	5.285864e-3
GO:0035617	stress granule disassembly	5.357587e-3
GO:0032074	negative regulation of nuclease activity	5.357587e-3
GO:0016570	histone modification	5.384600e-3
GO:0021521	ventral spinal cord interneuron specification	5.460131e-3
GO:0007049	cell cycle	5.650914e-3
GO:0010172	embryonic body morphogenesis	5.738178e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	5.834157e-3
GO:0016573	histone acetylation	5.862385e-3
GO:0007063	regulation of sister chromatid cohesion	5.923307e-3
GO:0006659	phosphatidylserine biosynthetic process	5.986888e-3
GO:0060242	contact inhibition	6.074014e-3
GO:0021771	lateral geniculate nucleus development	6.078040e-3
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	6.078040e-3
GO:0018065	protein-cofactor linkage	6.263376e-3
GO:0006914	autophagy	6.325120e-3
GO:0021514	ventral spinal cord interneuron differentiation	6.394515e-3
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	6.413017e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	6.413017e-3
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	6.413017e-3
GO:0002513	tolerance induction to self antigen	6.413017e-3
GO:0006611	protein export from nucleus	6.458454e-3
GO:0048341	paraxial mesoderm formation	6.553318e-3
GO:0006783	heme biosynthetic process	6.737874e-3
GO:0032508	DNA duplex unwinding	6.876061e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	7.424339e-3
GO:0033127	regulation of histone phosphorylation	7.531872e-3
GO:0051900	regulation of mitochondrial depolarization	7.627549e-3
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	7.721060e-3
GO:0016584	nucleosome positioning	7.809003e-3
GO:0048293	regulation of isotype switching to IgE isotypes	7.827585e-3
GO:0007031	peroxisome organization	7.930029e-3
GO:0046474	glycerophospholipid biosynthetic process	7.932390e-3
GO:0051901	positive regulation of mitochondrial depolarization	8.017709e-3
GO:0046580	negative regulation of Ras protein signal transduction	8.035818e-3
GO:0034645	cellular macromolecule biosynthetic process	8.243827e-3
GO:0051983	regulation of chromosome segregation	8.314894e-3
GO:0048339	paraxial mesoderm development	8.326880e-3
GO:0042245	RNA repair	8.446635e-3
GO:0071712	ER-associated misfolded protein catabolic process	8.446635e-3
GO:0003329	pancreatic PP cell fate commitment	8.446635e-3
GO:0003326	pancreatic A cell fate commitment	8.446635e-3
GO:0045905	positive regulation of translational termination	8.470051e-3
GO:0045901	positive regulation of translational elongation	8.470051e-3
GO:0006452	translational frameshifting	8.470051e-3
GO:0021513	spinal cord dorsal/ventral patterning	8.493347e-3
GO:0045647	negative regulation of erythrocyte differentiation	8.569771e-3
GO:0006824	cobalt ion transport	8.617395e-3
GO:0032392	DNA geometric change	8.882367e-3
GO:0032264	IMP salvage	9.032806e-3
GO:0032263	GMP salvage	9.032806e-3
GO:0046038	GMP catabolic process	9.032806e-3
GO:0048633	positive regulation of skeletal muscle tissue growth	9.032806e-3
GO:0010825	positive regulation of centrosome duplication	9.032806e-3
GO:0006178	guanine salvage	9.032806e-3
GO:0006713	glucocorticoid catabolic process	9.032806e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	9.105094e-3
GO:0051573	negative regulation of histone H3-K9 methylation	9.245246e-3
GO:0021612	facial nerve structural organization	9.245246e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	9.269814e-3
GO:0045063	T-helper 1 cell differentiation	9.269814e-3
GO:0030885	regulation of myeloid dendritic cell activation	9.318085e-3
GO:0034776	response to histamine	9.318085e-3
GO:0035470	positive regulation of vascular wound healing	9.318085e-3
GO:0018293	protein-FAD linkage	9.318085e-3
GO:0015761	mannose transport	9.318085e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	9.318085e-3
GO:0009234	menaquinone biosynthetic process	9.318085e-3
GO:0010616	negative regulation of cardiac muscle adaptation	9.318085e-3
GO:0007028	cytoplasm organization	9.340922e-3
GO:0021511	spinal cord patterning	9.505704e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.002413e-2
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	1.004803e-2
GO:0016558	protein import into peroxisome matrix	1.006364e-2
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.010776e-2
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	1.059474e-2
GO:0032713	negative regulation of interleukin-4 production	1.065444e-2
GO:0071422	succinate transmembrane transport	1.075125e-2
GO:0001830	trophectodermal cell fate commitment	1.075125e-2
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.075125e-2
GO:0021562	vestibulocochlear nerve development	1.080744e-2
GO:0016071	mRNA metabolic process	1.102729e-2
GO:0002701	negative regulation of production of molecular mediator of immune response	1.113776e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.114081e-2
GO:0051383	kinetochore organization	1.114081e-2
GO:0010388	cullin deneddylation	1.196441e-2
GO:0051603	proteolysis involved in cellular protein catabolic process	1.205478e-2
GO:0021943	formation of radial glial scaffolds	1.206466e-2
GO:0030336	negative regulation of cell migration	1.210423e-2
GO:0051225	spindle assembly	1.210679e-2
GO:0033013	tetrapyrrole metabolic process	1.225823e-2
GO:0051567	histone H3-K9 methylation	1.233203e-2
GO:0045292	nuclear mRNA cis splicing, via spliceosome	1.236758e-2
GO:0009143	nucleoside triphosphate catabolic process	1.240140e-2
GO:0071218	cellular response to misfolded protein	1.246549e-2
GO:0048246	macrophage chemotaxis	1.249782e-2
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.252538e-2
GO:0021506	anterior neuropore closure	1.252538e-2
GO:0007509	mesoderm migration involved in gastrulation	1.252538e-2
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.264950e-2
GO:0000087	M phase of mitotic cell cycle	1.269221e-2
GO:0016568	chromatin modification	1.347590e-2
GO:0035967	cellular response to topologically incorrect protein	1.357604e-2
GO:0032312	regulation of ARF GTPase activity	1.357604e-2
GO:0071476	cellular hypotonic response	1.358881e-2
GO:0051085	chaperone mediated protein folding requiring cofactor	1.365534e-2
GO:0046856	phosphatidylinositol dephosphorylation	1.368975e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.385256e-2
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	1.385256e-2
GO:0090182	regulation of secretion of lysosomal enzymes	1.385256e-2
GO:0090186	regulation of pancreatic juice secretion	1.385256e-2
GO:0051882	mitochondrial depolarization	1.385256e-2
GO:0003327	type B pancreatic cell fate commitment	1.385256e-2
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.385256e-2
GO:0046079	dUMP catabolic process	1.385256e-2
GO:0048550	negative regulation of pinocytosis	1.385256e-2
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	1.401356e-2
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.404843e-2
GO:0060209	estrus	1.406467e-2
GO:0090340	positive regulation of secretion of lysosomal enzymes	1.406467e-2
GO:0090187	positive regulation of pancreatic juice secretion	1.406467e-2
GO:0090108	positive regulation of high-density lipoprotein particle assembly	1.406467e-2
GO:0003419	growth plate cartilage chondrocyte proliferation	1.406467e-2
GO:0035087	siRNA loading onto RISC involved in RNA interference	1.406467e-2
GO:0043105	negative regulation of GTP cyclohydrolase I activity	1.406467e-2
GO:0009146	purine nucleoside triphosphate catabolic process	1.407933e-2
GO:0060124	positive regulation of growth hormone secretion	1.417768e-2
GO:2000114	regulation of establishment of cell polarity	1.417768e-2
GO:0018393	internal peptidyl-lysine acetylation	1.428648e-2
GO:0006325	chromatin organization	1.434711e-2
GO:0006680	glucosylceramide catabolic process	1.440610e-2
GO:0021997	neural plate axis specification	1.440610e-2
GO:0021754	facial nucleus development	1.440610e-2
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	1.446455e-2
GO:0031507	heterochromatin formation	1.446455e-2
GO:0034968	histone lysine methylation	1.447299e-2
GO:0009059	macromolecule biosynthetic process	1.448491e-2
GO:0048066	developmental pigmentation	1.450392e-2
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	1.453504e-2
GO:0071477	cellular hypotonic salinity response	1.453504e-2
GO:0021895	cerebral cortex neuron differentiation	1.488214e-2
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1.520873e-2
GO:0016926	protein desumoylation	1.520873e-2
GO:0043988	histone H3-S28 phosphorylation	1.521025e-2
GO:0051791	medium-chain fatty acid metabolic process	1.521025e-2
GO:0070625	zymogen granule exocytosis	1.521025e-2
GO:0043987	histone H3-S10 phosphorylation	1.521025e-2
GO:0010933	positive regulation of macrophage tolerance induction	1.521025e-2
GO:0002158	osteoclast proliferation	1.521025e-2
GO:0034134	toll-like receptor 2 signaling pathway	1.521025e-2
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	1.521025e-2
GO:0015724	formate transport	1.521025e-2
GO:0009394	2'-deoxyribonucleotide metabolic process	1.534095e-2
GO:0010592	positive regulation of lamellipodium assembly	1.548031e-2
GO:0009261	ribonucleotide catabolic process	1.592606e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.594631e-2
GO:0044257	cellular protein catabolic process	1.599118e-2
GO:0031536	positive regulation of exit from mitosis	1.618726e-2
GO:0018394	peptidyl-lysine acetylation	1.638676e-2
GO:0006268	DNA unwinding involved in replication	1.642417e-2
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.668598e-2
GO:0051001	negative regulation of nitric-oxide synthase activity	1.672026e-2
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.675397e-2
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.685762e-2
GO:0006449	regulation of translational termination	1.685762e-2
GO:0007265	Ras protein signal transduction	1.699360e-2
GO:0010390	histone monoubiquitination	1.712954e-2
GO:0045017	glycerolipid biosynthetic process	1.714526e-2
GO:0001574	ganglioside biosynthetic process	1.719656e-2
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.779806e-2
GO:0043966	histone H3 acetylation	1.783715e-2
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.830007e-2
GO:0043932	ossification involved in bone remodeling	1.830007e-2
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.830007e-2
GO:0032534	regulation of microvillus assembly	1.830007e-2
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.830007e-2
GO:0070172	positive regulation of tooth mineralization	1.837074e-2
GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	1.837074e-2
GO:0051081	nuclear envelope disassembly	1.837074e-2
GO:0042255	ribosome assembly	1.845618e-2
GO:0009200	deoxyribonucleoside triphosphate metabolic process	1.845618e-2
GO:0051351	positive regulation of ligase activity	1.847859e-2
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	1.864628e-2
GO:0008208	C21-steroid hormone catabolic process	1.864628e-2
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.870193e-2
GO:0043923	positive regulation by host of viral transcription	1.876895e-2
GO:0033128	negative regulation of histone phosphorylation	1.915297e-2
GO:0072537	fibroblast activation	1.915297e-2
GO:0030997	regulation of centriole-centriole cohesion	1.915297e-2
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.915297e-2
GO:0006498	N-terminal protein lipidation	1.915297e-2
GO:0090076	relaxation of skeletal muscle	1.917968e-2
GO:0043654	recognition of apoptotic cell	1.917968e-2
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.917968e-2
GO:0032872	regulation of stress-activated MAPK cascade	1.929091e-2
GO:2000146	negative regulation of cell motility	1.930922e-2
GO:0018410	C-terminal protein amino acid modification	1.947235e-2
GO:0003218	cardiac left ventricle formation	1.951105e-2
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.981833e-2
GO:0007067	mitosis	1.987824e-2
GO:0009154	purine ribonucleotide catabolic process	1.997617e-2
GO:0006260	DNA replication	1.999604e-2
GO:0046148	pigment biosynthetic process	2.005856e-2
GO:0030262	apoptotic nuclear change	2.038437e-2
GO:0071353	cellular response to interleukin-4	2.076744e-2
GO:0045920	negative regulation of exocytosis	2.088054e-2
GO:0021520	spinal cord motor neuron cell fate specification	2.088341e-2
GO:0016458	gene silencing	2.153568e-2
GO:2000143	negative regulation of transcription initiation, DNA-dependent	2.198370e-2
GO:0046323	glucose import	2.198370e-2
GO:0008105	asymmetric protein localization	2.237581e-2
GO:0000281	cytokinesis after mitosis	2.258400e-2
GO:0050774	negative regulation of dendrite morphogenesis	2.267423e-2
GO:0034142	toll-like receptor 4 signaling pathway	2.287646e-2
GO:0001845	phagolysosome assembly	2.287646e-2
GO:0031999	negative regulation of fatty acid beta-oxidation	2.287646e-2
GO:0051005	negative regulation of lipoprotein lipase activity	2.292540e-2
GO:0021892	cerebral cortex GABAergic interneuron differentiation	2.292540e-2
GO:0051775	response to redox state	2.300052e-2
GO:0009156	ribonucleoside monophosphate biosynthetic process	2.374848e-2
GO:0048294	negative regulation of isotype switching to IgE isotypes	2.399162e-2