Novel motif:115

name:	motif115_CATCAACTAC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0044243	multicellular organismal catabolic process	1.302278e-11
GO:0030029	actin filament-based process	1.004446e-10
GO:0006434	seryl-tRNA aminoacylation	1.791068e-10
GO:0030036	actin cytoskeleton organization	2.023523e-10
GO:0007094	mitotic cell cycle spindle assembly checkpoint	2.936352e-10
GO:0071173	spindle assembly checkpoint	3.862465e-10
GO:0071174	mitotic cell cycle spindle checkpoint	4.078152e-10
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	5.938973e-10
GO:0031577	spindle checkpoint	6.262653e-10
GO:0018350	protein esterification	2.229112e-9
GO:0044258	intestinal lipid catabolic process	2.229112e-9
GO:0015891	siderophore transport	2.229112e-9
GO:0030241	skeletal muscle myosin thick filament assembly	2.400416e-9
GO:0044240	multicellular organismal lipid catabolic process	3.366800e-9
GO:0014866	skeletal myofibril assembly	8.709026e-9
GO:0045839	negative regulation of mitosis	8.802602e-9
GO:0030071	regulation of mitotic metaphase/anaphase transition	9.099056e-9
GO:0030261	chromosome condensation	1.696368e-8
GO:0003012	muscle system process	3.026763e-8
GO:0000075	cell cycle checkpoint	8.449988e-8
GO:0031397	negative regulation of protein ubiquitination	1.031398e-7
GO:0048769	sarcomerogenesis	1.075865e-7
GO:0030240	skeletal muscle thin filament assembly	1.338373e-7
GO:0007076	mitotic chromosome condensation	1.535126e-7
GO:0006418	tRNA aminoacylation for protein translation	2.048701e-7
GO:0048739	cardiac muscle fiber development	2.268367e-7
GO:0055003	cardiac myofibril assembly	2.830890e-7
GO:0071732	cellular response to nitric oxide	2.904368e-7
GO:0007093	mitotic cell cycle checkpoint	2.908900e-7
GO:0030149	sphingolipid catabolic process	3.355344e-7
GO:0035051	cardiac cell differentiation	3.919059e-7
GO:0044236	multicellular organismal metabolic process	4.121927e-7
GO:0046514	ceramide catabolic process	4.533808e-7
GO:0006936	muscle contraction	5.089098e-7
GO:0071156	regulation of cell cycle arrest	5.455927e-7
GO:0046466	membrane lipid catabolic process	6.451822e-7
GO:0051592	response to calcium ion	9.273055e-7
GO:0072560	type B pancreatic cell maturation	9.289160e-7
GO:0007015	actin filament organization	9.304136e-7
GO:0031532	actin cytoskeleton reorganization	9.959978e-7
GO:0043589	skin morphogenesis	1.080516e-6
GO:0055007	cardiac muscle cell differentiation	1.275684e-6
GO:0010927	cellular component assembly involved in morphogenesis	1.455466e-6
GO:0046521	sphingoid catabolic process	1.703785e-6
GO:0055013	cardiac muscle cell development	1.770596e-6
GO:0006323	DNA packaging	2.253495e-6
GO:0006432	phenylalanyl-tRNA aminoacylation	2.335489e-6
GO:0060285	ciliary cell motility	2.416632e-6
GO:0043039	tRNA aminoacylation	2.453933e-6
GO:0000819	sister chromatid segregation	3.276006e-6
GO:0000070	mitotic sister chromatid segregation	3.747001e-6
GO:0043004	cytoplasmic sequestering of CFTR protein	4.838385e-6
GO:0043353	enucleate erythrocyte differentiation	5.302873e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	5.420710e-6
GO:0042363	fat-soluble vitamin catabolic process	5.516750e-6
GO:0030157	pancreatic juice secretion	6.247412e-6
GO:0006768	biotin metabolic process	6.530511e-6
GO:0006552	leucine catabolic process	6.530511e-6
GO:0015696	ammonium transport	7.047155e-6
GO:0070682	proteasome regulatory particle assembly	7.140410e-6
GO:0030239	myofibril assembly	7.918839e-6
GO:0050658	RNA transport	8.979104e-6
GO:0006941	striated muscle contraction	9.017691e-6
GO:2000078	positive regulation of type B pancreatic cell development	9.764654e-6
GO:0070252	actin-mediated cell contraction	1.077271e-5
GO:0042921	glucocorticoid receptor signaling pathway	1.169679e-5
GO:0031396	regulation of protein ubiquitination	1.182858e-5
GO:0031958	corticosteroid receptor signaling pathway	1.200230e-5
GO:0009987	cellular process	1.251948e-5
GO:0050896	response to stimulus	1.346627e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.455426e-5
GO:0003008	system process	1.456164e-5
GO:0051208	sequestering of calcium ion	1.659451e-5
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.715824e-5
GO:0007204	elevation of cytosolic calcium ion concentration	1.727487e-5
GO:0030260	entry into host cell	2.327631e-5
GO:0006403	RNA localization	2.688764e-5
GO:0071731	response to nitric oxide	2.704346e-5
GO:0051276	chromosome organization	2.930354e-5
GO:0071241	cellular response to inorganic substance	2.966572e-5
GO:0048738	cardiac muscle tissue development	3.090000e-5
GO:0010035	response to inorganic substance	3.189698e-5
GO:0045214	sarcomere organization	3.211798e-5
GO:0030154	cell differentiation	3.236154e-5
GO:0006826	iron ion transport	3.481299e-5
GO:0009888	tissue development	4.153692e-5
GO:0007088	regulation of mitosis	4.193847e-5
GO:0030049	muscle filament sliding	4.351679e-5
GO:0002017	regulation of blood volume by renal aldosterone	4.389070e-5
GO:0006422	aspartyl-tRNA aminoacylation	4.584570e-5
GO:0006399	tRNA metabolic process	4.717639e-5
GO:0055065	metal ion homeostasis	4.823789e-5
GO:0048747	muscle fiber development	4.873364e-5
GO:0071103	DNA conformation change	5.060822e-5
GO:0051220	cytoplasmic sequestering of protein	5.061227e-5
GO:0060301	positive regulation of cytokine activity	5.080590e-5
GO:0048869	cellular developmental process	5.565927e-5
GO:0031032	actomyosin structure organization	6.032722e-5
GO:0006875	cellular metal ion homeostasis	6.131834e-5
GO:0007398	ectoderm development	6.167836e-5
GO:0002522	leukocyte migration involved in immune response	6.281403e-5
GO:0050878	regulation of body fluid levels	6.504692e-5
GO:0030003	cellular cation homeostasis	6.837136e-5
GO:0030048	actin filament-based movement	6.865058e-5
GO:0006551	leucine metabolic process	7.451919e-5
GO:0051444	negative regulation of ubiquitin-protein ligase activity	7.656758e-5
GO:0007256	activation of JNKK activity	7.823516e-5
GO:0070741	response to interleukin-6	7.987177e-5
GO:0090304	nucleic acid metabolic process	8.087893e-5
GO:0032423	regulation of mismatch repair	8.144681e-5
GO:2000074	regulation of type B pancreatic cell development	8.426898e-5
GO:0018293	protein-FAD linkage	8.732473e-5
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	8.732473e-5
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	8.849853e-5
GO:0055002	striated muscle cell development	9.096194e-5
GO:0055008	cardiac muscle tissue morphogenesis	9.644759e-5
GO:0033198	response to ATP	9.829132e-5
GO:0021636	trigeminal nerve morphogenesis	9.909770e-5
GO:0048935	peripheral nervous system neuron development	1.063810e-4
GO:0003215	cardiac right ventricle morphogenesis	1.150355e-4
GO:0006665	sphingolipid metabolic process	1.155174e-4
GO:0010966	regulation of phosphate transport	1.184238e-4
GO:0007010	cytoskeleton organization	1.200123e-4
GO:0051488	activation of anaphase-promoting complex activity	1.314164e-4
GO:0003341	cilium movement	1.327655e-4
GO:0006707	cholesterol catabolic process	1.338772e-4
GO:0032425	positive regulation of mismatch repair	1.364411e-4
GO:0010524	positive regulation of calcium ion transport into cytosol	1.416906e-4
GO:0060413	atrial septum morphogenesis	1.582965e-4
GO:0055080	cation homeostasis	1.696814e-4
GO:0051901	positive regulation of mitochondrial depolarization	1.719663e-4
GO:0055093	response to hyperoxia	1.742876e-4
GO:0055001	muscle cell development	1.830203e-4
GO:0071347	cellular response to interleukin-1	1.848132e-4
GO:0006766	vitamin metabolic process	1.867659e-4
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.874281e-4
GO:0034660	ncRNA metabolic process	1.892340e-4
GO:0070208	protein heterotrimerization	1.924519e-4
GO:0008211	glucocorticoid metabolic process	2.125898e-4
GO:0060415	muscle tissue morphogenesis	2.150613e-4
GO:0032417	positive regulation of sodium:hydrogen antiporter activity	2.250230e-4
GO:0014052	regulation of gamma-aminobutyric acid secretion	2.493649e-4
GO:0007413	axonal fasciculation	2.545134e-4
GO:0002407	dendritic cell chemotaxis	2.672608e-4
GO:0006643	membrane lipid metabolic process	2.712846e-4
GO:0030518	steroid hormone receptor signaling pathway	2.736020e-4
GO:0009605	response to external stimulus	2.754326e-4
GO:0043402	glucocorticoid mediated signaling pathway	2.820814e-4
GO:0051480	cytosolic calcium ion homeostasis	3.433057e-4
GO:0009617	response to bacterium	3.484312e-4
GO:0034120	positive regulation of erythrocyte aggregation	3.536496e-4
GO:0051235	maintenance of location	3.756734e-4
GO:0043982	histone H4-K8 acetylation	3.885314e-4
GO:0043981	histone H4-K5 acetylation	3.885314e-4
GO:0007250	activation of NF-kappaB-inducing kinase activity	3.900754e-4
GO:0006968	cellular defense response	3.989549e-4
GO:0048549	positive regulation of pinocytosis	4.215970e-4
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	4.215970e-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.296263e-4
GO:0019438	aromatic compound biosynthetic process	4.330033e-4
GO:0019882	antigen processing and presentation	4.341633e-4
GO:0060300	regulation of cytokine activity	4.349164e-4
GO:0032501	multicellular organismal process	4.541317e-4
GO:0010948	negative regulation of cell cycle process	4.636381e-4
GO:0071230	cellular response to amino acid stimulus	4.710343e-4
GO:0022614	membrane to membrane docking	4.766220e-4
GO:0070206	protein trimerization	4.906069e-4
GO:0014706	striated muscle tissue development	5.019165e-4
GO:0071299	cellular response to vitamin A	5.171393e-4
GO:0003283	atrial septum development	5.195056e-4
GO:0015671	oxygen transport	5.201244e-4
GO:0033189	response to vitamin A	5.414618e-4
GO:0085029	extracellular matrix assembly	5.661043e-4
GO:0032507	maintenance of protein location in cell	5.683214e-4
GO:0007136	meiotic prophase II	5.683421e-4
GO:0042427	serotonin biosynthetic process	5.711071e-4
GO:0032502	developmental process	6.241989e-4
GO:0046519	sphingoid metabolic process	6.281230e-4
GO:0006672	ceramide metabolic process	6.580674e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	7.163176e-4
GO:0032203	telomere formation via telomerase	7.170011e-4
GO:0003017	lymph circulation	7.259973e-4
GO:0009635	response to herbicide	7.379672e-4
GO:0001957	intramembranous ossification	7.669570e-4
GO:0050900	leukocyte migration	7.854677e-4
GO:0031344	regulation of cell projection organization	8.057429e-4
GO:0044259	multicellular organismal macromolecule metabolic process	8.519162e-4
GO:0032963	collagen metabolic process	8.597876e-4
GO:0043116	negative regulation of vascular permeability	8.683972e-4
GO:0032308	positive regulation of prostaglandin secretion	8.705075e-4
GO:0032861	activation of Rap GTPase activity	9.039800e-4
GO:0015758	glucose transport	9.142904e-4
GO:0015931	nucleobase-containing compound transport	9.197160e-4
GO:0071285	cellular response to lithium ion	9.245927e-4
GO:0070634	transepithelial ammonium transport	9.271625e-4
GO:0003211	cardiac ventricle formation	9.318287e-4
GO:0030574	collagen catabolic process	9.350409e-4
GO:0071300	cellular response to retinoic acid	9.630111e-4
GO:0048644	muscle organ morphogenesis	9.633840e-4
GO:0033523	histone H2B ubiquitination	9.710105e-4
GO:0045070	positive regulation of viral genome replication	9.933066e-4
GO:0006508	proteolysis	9.973647e-4
GO:0002237	response to molecule of bacterial origin	1.000438e-3
GO:0008645	hexose transport	1.009021e-3
GO:0030522	intracellular receptor mediated signaling pathway	1.038808e-3
GO:0001560	regulation of cell growth by extracellular stimulus	1.044321e-3
GO:0015749	monosaccharide transport	1.059533e-3
GO:0071286	cellular response to magnesium ion	1.061023e-3
GO:0007159	leukocyte cell-cell adhesion	1.077086e-3
GO:0044241	lipid digestion	1.114196e-3
GO:0051930	regulation of sensory perception of pain	1.118526e-3
GO:0007623	circadian rhythm	1.121680e-3
GO:0006704	glucocorticoid biosynthetic process	1.147875e-3
GO:0071418	cellular response to amine stimulus	1.154328e-3
GO:0033572	transferrin transport	1.200598e-3
GO:0030163	protein catabolic process	1.203679e-3
GO:0003209	cardiac atrium morphogenesis	1.206988e-3
GO:0014048	regulation of glutamate secretion	1.206988e-3
GO:0070375	BMK cascade	1.210587e-3
GO:0015942	formate metabolic process	1.210587e-3
GO:0071460	cellular response to cell-matrix adhesion	1.210744e-3
GO:0048513	organ development	1.211930e-3
GO:0006026	aminoglycan catabolic process	1.211978e-3
GO:0007585	respiratory gaseous exchange	1.233142e-3
GO:0071295	cellular response to vitamin	1.236015e-3
GO:0065008	regulation of biological quality	1.247637e-3
GO:0042558	pteridine-containing compound metabolic process	1.284953e-3
GO:0007219	Notch signaling pathway	1.297791e-3
GO:0071417	cellular response to organic nitrogen	1.304979e-3
GO:0048548	regulation of pinocytosis	1.307423e-3
GO:0043132	NAD transport	1.311565e-3
GO:0040040	thermosensory behavior	1.318415e-3
GO:0033273	response to vitamin	1.324476e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.350543e-3
GO:0090277	positive regulation of peptide hormone secretion	1.407284e-3
GO:0003323	type B pancreatic cell development	1.408770e-3
GO:0030007	cellular potassium ion homeostasis	1.433419e-3
GO:0060537	muscle tissue development	1.444074e-3
GO:0006032	chitin catabolic process	1.456934e-3
GO:0043217	myelin maintenance	1.456934e-3
GO:0006396	RNA processing	1.463162e-3
GO:0006700	C21-steroid hormone biosynthetic process	1.471258e-3
GO:0070271	protein complex biogenesis	1.502350e-3
GO:0071229	cellular response to acid	1.525966e-3
GO:0007270	neuron-neuron synaptic transmission	1.557444e-3
GO:0015669	gas transport	1.566123e-3
GO:0042098	T cell proliferation	1.576981e-3
GO:0002793	positive regulation of peptide secretion	1.610948e-3
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	1.616430e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.616430e-3
GO:0000296	spermine transport	1.616430e-3
GO:0051146	striated muscle cell differentiation	1.672536e-3
GO:0070849	response to epidermal growth factor stimulus	1.678900e-3
GO:0071496	cellular response to external stimulus	1.725615e-3
GO:0051056	regulation of small GTPase mediated signal transduction	1.759588e-3
GO:0042692	muscle cell differentiation	1.772831e-3
GO:0015991	ATP hydrolysis coupled proton transport	1.786969e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.789572e-3
GO:0047496	vesicle transport along microtubule	1.790424e-3
GO:0034644	cellular response to UV	1.860592e-3
GO:0006461	protein complex assembly	1.889264e-3
GO:0044257	cellular protein catabolic process	1.904286e-3
GO:0030199	collagen fibril organization	1.921380e-3
GO:0048730	epidermis morphogenesis	1.922624e-3
GO:0090276	regulation of peptide hormone secretion	1.942485e-3
GO:0032024	positive regulation of insulin secretion	1.974552e-3
GO:0045185	maintenance of protein location	1.974733e-3
GO:0070734	histone H3-K27 methylation	1.975908e-3
GO:0030299	intestinal cholesterol absorption	1.979294e-3
GO:0032892	positive regulation of organic acid transport	1.995664e-3
GO:0009258	10-formyltetrahydrofolate catabolic process	2.026688e-3
GO:0051238	sequestering of metal ion	2.068090e-3
GO:0031570	DNA integrity checkpoint	2.075185e-3
GO:0032320	positive regulation of Ras GTPase activity	2.118272e-3
GO:0042384	cilium assembly	2.121032e-3
GO:0032854	positive regulation of Rap GTPase activity	2.127558e-3
GO:0051928	positive regulation of calcium ion transport	2.164475e-3
GO:0043983	histone H4-K12 acetylation	2.170242e-3
GO:0007599	hemostasis	2.172864e-3
GO:0003230	cardiac atrium development	2.204433e-3
GO:0002791	regulation of peptide secretion	2.221079e-3
GO:0046578	regulation of Ras protein signal transduction	2.239464e-3
GO:0010038	response to metal ion	2.243133e-3
GO:0022417	protein maturation by protein folding	2.291648e-3
GO:0043632	modification-dependent macromolecule catabolic process	2.297247e-3
GO:0051651	maintenance of location in cell	2.297657e-3
GO:0006259	DNA metabolic process	2.323475e-3
GO:0044282	small molecule catabolic process	2.460367e-3
GO:2000124	regulation of endocannabinoid signaling pathway	2.465716e-3
GO:0050796	regulation of insulin secretion	2.510788e-3
GO:0006874	cellular calcium ion homeostasis	2.559510e-3
GO:0007601	visual perception	2.568773e-3
GO:0006706	steroid catabolic process	2.587076e-3
GO:0044254	multicellular organismal protein catabolic process	2.619901e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	2.630224e-3
GO:0050717	positive regulation of interleukin-1 alpha secretion	2.630224e-3
GO:0021854	hypothalamus development	2.634699e-3
GO:0071248	cellular response to metal ion	2.655628e-3
GO:0043968	histone H2A acetylation	2.685804e-3
GO:0042559	pteridine-containing compound biosynthetic process	2.698338e-3
GO:0045815	positive regulation of gene expression, epigenetic	2.770748e-3
GO:0050953	sensory perception of light stimulus	2.794056e-3
GO:0043248	proteasome assembly	2.796507e-3
GO:0014745	negative regulation of muscle adaptation	2.843416e-3
GO:0034612	response to tumor necrosis factor	2.847612e-3
GO:0048251	elastic fiber assembly	2.899127e-3
GO:0032496	response to lipopolysaccharide	2.934516e-3
GO:0031943	regulation of glucocorticoid metabolic process	2.985304e-3
GO:2000193	positive regulation of fatty acid transport	2.985304e-3
GO:0019987	negative regulation of anti-apoptosis	2.986877e-3
GO:0007596	blood coagulation	3.133122e-3
GO:0000077	DNA damage checkpoint	3.139258e-3
GO:0046883	regulation of hormone secretion	3.171872e-3
GO:0043623	cellular protein complex assembly	3.240829e-3
GO:0043949	regulation of cAMP-mediated signaling	3.242979e-3
GO:0090231	regulation of spindle checkpoint	3.243687e-3
GO:0006767	water-soluble vitamin metabolic process	3.280338e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.281803e-3
GO:0051017	actin filament bundle assembly	3.305511e-3
GO:0014049	positive regulation of glutamate secretion	3.318243e-3
GO:0051709	regulation of killing of cells of other organism	3.322366e-3
GO:0044268	multicellular organismal protein metabolic process	3.403676e-3
GO:0070560	protein secretion by platelet	3.403676e-3
GO:0060305	regulation of cell diameter	3.403676e-3
GO:0030845	inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway	3.403676e-3
GO:0010920	negative regulation of inositol phosphate biosynthetic process	3.403676e-3
GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity	3.403676e-3
GO:0044154	histone H3-K14 acetylation	3.403676e-3
GO:0019233	sensory perception of pain	3.408687e-3
GO:0019059	initiation of viral infection	3.411185e-3
GO:0006937	regulation of muscle contraction	3.463864e-3
GO:0030218	erythrocyte differentiation	3.466618e-3
GO:0072503	cellular divalent inorganic cation homeostasis	3.470977e-3
GO:0030168	platelet activation	3.537222e-3
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	3.543006e-3
GO:0044085	cellular component biogenesis	3.556528e-3
GO:0007016	cytoskeletal anchoring at plasma membrane	3.587418e-3
GO:0031670	cellular response to nutrient	3.604381e-3
GO:0007586	digestion	3.610155e-3
GO:0048729	tissue morphogenesis	3.639477e-3
GO:0044260	cellular macromolecule metabolic process	3.646852e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	3.698735e-3
GO:0051973	positive regulation of telomerase activity	3.712658e-3
GO:0018027	peptidyl-lysine dimethylation	3.726528e-3
GO:0001666	response to hypoxia	3.763659e-3
GO:0070493	thrombin receptor signaling pathway	3.927995e-3
GO:0090257	regulation of muscle system process	3.993883e-3
GO:0006935	chemotaxis	4.073801e-3
GO:0055074	calcium ion homeostasis	4.088787e-3
GO:0007443	Malpighian tubule morphogenesis	4.094766e-3
GO:0070367	negative regulation of hepatocyte differentiation	4.094766e-3
GO:0007155	cell adhesion	4.118769e-3
GO:0019941	modification-dependent protein catabolic process	4.129302e-3
GO:0071385	cellular response to glucocorticoid stimulus	4.216813e-3
GO:0007275	multicellular organismal development	4.235854e-3
GO:0045794	negative regulation of cell volume	4.237412e-3
GO:0009451	RNA modification	4.250321e-3
GO:0048485	sympathetic nervous system development	4.331645e-3
GO:0006511	ubiquitin-dependent protein catabolic process	4.352227e-3
GO:0018026	peptidyl-lysine monomethylation	4.362141e-3
GO:0090232	positive regulation of spindle checkpoint	4.511393e-3
GO:0048699	generation of neurons	4.523482e-3
GO:0042074	cell migration involved in gastrulation	4.553412e-3
GO:0051028	mRNA transport	4.621766e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.653163e-3
GO:0032730	positive regulation of interleukin-1 alpha production	4.653163e-3
GO:0046887	positive regulation of hormone secretion	4.673012e-3
GO:0022008	neurogenesis	4.738912e-3
GO:0008333	endosome to lysosome transport	4.818530e-3
GO:0048731	system development	4.826978e-3
GO:0060929	atrioventricular node cell fate commitment	4.842989e-3
GO:0060928	atrioventricular node cell development	4.842989e-3
GO:0003342	proepicardium development	4.842989e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	4.842989e-3
GO:0022607	cellular component assembly	4.893929e-3
GO:0002376	immune system process	4.955785e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	5.024903e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	5.027614e-3
GO:0006879	cellular iron ion homeostasis	5.027614e-3
GO:0032383	regulation of intracellular cholesterol transport	5.155048e-3
GO:0021785	branchiomotor neuron axon guidance	5.155048e-3
GO:0043170	macromolecule metabolic process	5.190040e-3
GO:0014889	muscle atrophy	5.191196e-3
GO:0045739	positive regulation of DNA repair	5.287477e-3
GO:0006663	platelet activating factor biosynthetic process	5.357208e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	5.376767e-3
GO:0010564	regulation of cell cycle process	5.389310e-3
GO:0007198	inhibition of adenylate cyclase activity by serotonin receptor signaling pathway	5.402657e-3
GO:0072507	divalent inorganic cation homeostasis	5.435326e-3
GO:0044242	cellular lipid catabolic process	5.492065e-3
GO:0031667	response to nutrient levels	5.562953e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	5.668353e-3
GO:0007135	meiosis II	5.668353e-3
GO:0045664	regulation of neuron differentiation	5.716268e-3
GO:0046219	indolalkylamine biosynthetic process	5.738989e-3
GO:0042996	regulation of Golgi to plasma membrane protein transport	5.738989e-3
GO:0014823	response to activity	5.750146e-3
GO:0030836	positive regulation of actin filament depolymerization	5.914201e-3
GO:0042107	cytokine metabolic process	6.122427e-3
GO:0032202	telomere assembly	6.208373e-3
GO:0048856	anatomical structure development	6.244575e-3
GO:0021522	spinal cord motor neuron differentiation	6.276397e-3
GO:0045859	regulation of protein kinase activity	6.285241e-3
GO:0070887	cellular response to chemical stimulus	6.292882e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	6.297010e-3
GO:0008628	induction of apoptosis by hormones	6.297010e-3
GO:0016032	viral reproduction	6.443583e-3
GO:0007289	spermatid nucleus differentiation	6.465860e-3
GO:0051452	intracellular pH reduction	6.519262e-3
GO:0043137	DNA replication, removal of RNA primer	6.572860e-3
GO:0065007	biological regulation	6.582384e-3
GO:0071495	cellular response to endogenous stimulus	6.645807e-3
GO:0070555	response to interleukin-1	6.672001e-3
GO:0010517	regulation of phospholipase activity	6.680259e-3
GO:0055014	atrial cardiac muscle cell development	6.751155e-3
GO:0032088	negative regulation of NF-kappaB transcription factor activity	6.772523e-3
GO:0008038	neuron recognition	6.857648e-3
GO:0015031	protein transport	6.872203e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	6.874604e-3
GO:0035090	maintenance of apical/basal cell polarity	6.874604e-3
GO:0006683	galactosylceramide catabolic process	6.874604e-3
GO:0031399	regulation of protein modification process	6.970928e-3
GO:0021761	limbic system development	7.036009e-3
GO:0030041	actin filament polymerization	7.060262e-3
GO:0051168	nuclear export	7.097469e-3
GO:0048096	chromatin-mediated maintenance of transcription	7.104196e-3
GO:0051707	response to other organism	7.107747e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	7.197121e-3
GO:0050767	regulation of neurogenesis	7.322930e-3
GO:0009991	response to extracellular stimulus	7.439893e-3
GO:0061136	regulation of proteasomal protein catabolic process	7.477103e-3
GO:0008054	cyclin catabolic process	7.494975e-3
GO:0060841	venous blood vessel development	7.507223e-3
GO:0045666	positive regulation of neuron differentiation	7.519964e-3
GO:0007506	gonadal mesoderm development	7.522413e-3
GO:0003309	type B pancreatic cell differentiation	7.524730e-3
GO:0015872	dopamine transport	7.531805e-3
GO:0000041	transition metal ion transport	7.540298e-3
GO:0010639	negative regulation of organelle organization	7.587606e-3
GO:0046653	tetrahydrofolate metabolic process	7.629565e-3
GO:0071478	cellular response to radiation	7.679782e-3
GO:0035729	cellular response to hepatocyte growth factor stimulus	7.838798e-3
GO:0035435	phosphate ion transmembrane transport	7.845266e-3
GO:0071844	cellular component assembly at cellular level	7.950371e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	7.974493e-3
GO:0031668	cellular response to extracellular stimulus	7.984058e-3
GO:0034465	response to carbon monoxide	8.013386e-3
GO:0007411	axon guidance	8.033010e-3
GO:0051701	interaction with host	8.068549e-3
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	8.169709e-3
GO:0006950	response to stress	8.187406e-3
GO:0033043	regulation of organelle organization	8.236447e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	8.250212e-3
GO:0065003	macromolecular complex assembly	8.397798e-3
GO:0042118	endothelial cell activation	8.447359e-3
GO:0010519	negative regulation of phospholipase activity	8.447359e-3
GO:0035587	purinergic receptor signaling pathway	8.467421e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	8.480843e-3
GO:0045184	establishment of protein localization	8.514127e-3
GO:0010332	response to gamma radiation	8.518170e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	8.599414e-3
GO:0045793	positive regulation of cell size	8.602477e-3
GO:0071526	semaphorin-plexin signaling pathway	8.608936e-3
GO:0010522	regulation of calcium ion transport into cytosol	8.854648e-3
GO:0007509	mesoderm migration involved in gastrulation	8.897918e-3
GO:0046164	alcohol catabolic process	8.905653e-3
GO:0034589	hydroxyproline transport	8.935609e-3
GO:0030263	apoptotic chromosome condensation	8.935609e-3
GO:0015826	threonine transport	8.935609e-3
GO:0042420	dopamine catabolic process	8.968578e-3
GO:0042094	interleukin-2 biosynthetic process	8.968578e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	9.030114e-3
GO:0090317	negative regulation of intracellular protein transport	9.114447e-3
GO:0008207	C21-steroid hormone metabolic process	9.146603e-3
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	9.279367e-3
GO:0034220	ion transmembrane transport	9.318249e-3
GO:0060411	cardiac septum morphogenesis	9.332492e-3
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	9.368741e-3
GO:0045204	MAPK export from nucleus	9.368741e-3
GO:0010934	macrophage cytokine production	9.368741e-3
GO:0014909	smooth muscle cell migration	9.368741e-3
GO:0048646	anatomical structure formation involved in morphogenesis	9.399383e-3
GO:0009062	fatty acid catabolic process	9.420116e-3
GO:0042060	wound healing	9.479037e-3
GO:0055082	cellular chemical homeostasis	9.590639e-3
GO:0060971	embryonic heart tube left/right pattern formation	9.778167e-3
GO:0060920	pacemaker cell differentiation	9.778167e-3
GO:0060402	calcium ion transport into cytosol	9.778589e-3
GO:0030185	nitric oxide transport	9.780123e-3
GO:0045851	pH reduction	9.832798e-3
GO:0042723	thiamine-containing compound metabolic process	9.850120e-3
GO:0051704	multi-organism process	9.945387e-3
GO:0032602	chemokine production	9.965300e-3
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	9.965300e-3
GO:0009607	response to biotic stimulus	1.000011e-2
GO:0070482	response to oxygen levels	1.002812e-2
GO:0045988	negative regulation of striated muscle contraction	1.012357e-2
GO:0070588	calcium ion transmembrane transport	1.024683e-2
GO:0003357	noradrenergic neuron differentiation	1.036570e-2
GO:0044237	cellular metabolic process	1.040143e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006957	complement activation, alternative pathway	8.188721e-11
GO:0048240	sperm capacitation	1.023839e-10
GO:0002920	regulation of humoral immune response	1.703005e-10
GO:0043056	forward locomotion	3.290837e-10
GO:0002889	regulation of immunoglobulin mediated immune response	3.947778e-10
GO:0006958	complement activation, classical pathway	5.612969e-10
GO:0033058	directional locomotion	2.604118e-9
GO:0055003	cardiac myofibril assembly	9.176960e-9
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.422737e-8
GO:0006278	RNA-dependent DNA replication	1.670098e-8
GO:0021758	putamen development	3.356244e-8
GO:0021757	caudate nucleus development	3.356244e-8
GO:0001970	positive regulation of activation of membrane attack complex	4.088646e-8
GO:0002922	positive regulation of humoral immune response	5.624093e-8
GO:0001969	regulation of activation of membrane attack complex	9.286383e-8
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.160894e-7
GO:0071230	cellular response to amino acid stimulus	1.259643e-7
GO:0002253	activation of immune response	1.403162e-7
GO:0006956	complement activation	1.450864e-7
GO:0002449	lymphocyte mediated immunity	1.839514e-7
GO:0055114	oxidation-reduction process	2.020643e-7
GO:0001974	blood vessel remodeling	2.272425e-7
GO:0072376	protein activation cascade	2.591482e-7
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.890156e-7
GO:0071229	cellular response to acid	2.997750e-7
GO:0035674	tricarboxylic acid transmembrane transport	3.011831e-7
GO:0009052	pentose-phosphate shunt, non-oxidative branch	3.757868e-7
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	5.078928e-7
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	5.445323e-7
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5.836667e-7
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.740494e-7
GO:0006189	'de novo' IMP biosynthetic process	6.759217e-7
GO:0002706	regulation of lymphocyte mediated immunity	6.974663e-7
GO:0002443	leukocyte mediated immunity	7.224080e-7
GO:0045087	innate immune response	7.835955e-7
GO:0006952	defense response	8.112102e-7
GO:0035634	response to stilbenoid	8.509316e-7
GO:0055013	cardiac muscle cell development	8.801261e-7
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.029338e-6
GO:0010954	positive regulation of protein processing	1.040526e-6
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	1.168943e-6
GO:0042297	vocal learning	1.284746e-6
GO:0050776	regulation of immune response	1.439373e-6
GO:0002819	regulation of adaptive immune response	1.479505e-6
GO:0050778	positive regulation of immune response	1.641646e-6
GO:0001798	positive regulation of type IIa hypersensitivity	1.819292e-6
GO:0055006	cardiac cell development	2.111574e-6
GO:0071418	cellular response to amine stimulus	2.682567e-6
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2.729709e-6
GO:0050777	negative regulation of immune response	2.763148e-6
GO:0019693	ribose phosphate metabolic process	2.774862e-6
GO:0002885	positive regulation of hypersensitivity	2.774862e-6
GO:0006164	purine nucleotide biosynthetic process	2.906287e-6
GO:0002883	regulation of hypersensitivity	3.130034e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	3.347865e-6
GO:0015746	citrate transport	3.347865e-6
GO:0071417	cellular response to organic nitrogen	3.492507e-6
GO:0002891	positive regulation of immunoglobulin mediated immune response	3.735880e-6
GO:0009987	cellular process	3.867725e-6
GO:0030199	collagen fibril organization	4.008590e-6
GO:0009115	xanthine catabolic process	4.671124e-6
GO:0015761	mannose transport	5.110326e-6
GO:0002252	immune effector process	5.580021e-6
GO:0006014	D-ribose metabolic process	6.434972e-6
GO:0071422	succinate transmembrane transport	6.709545e-6
GO:0071702	organic substance transport	7.817025e-6
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	8.750697e-6
GO:0006415	translational termination	1.073741e-5
GO:0072522	purine-containing compound biosynthetic process	1.082262e-5
GO:0016064	immunoglobulin mediated immune response	1.254064e-5
GO:0002821	positive regulation of adaptive immune response	1.302966e-5
GO:0006188	IMP biosynthetic process	1.331666e-5
GO:0050860	negative regulation of T cell receptor signaling pathway	1.364433e-5
GO:0070208	protein heterotrimerization	1.411892e-5
GO:0019724	B cell mediated immunity	1.457790e-5
GO:0009165	nucleotide biosynthetic process	1.489368e-5
GO:0002551	mast cell chemotaxis	1.492658e-5
GO:0030449	regulation of complement activation	1.680442e-5
GO:0002703	regulation of leukocyte mediated immunity	1.927973e-5
GO:0006144	purine base metabolic process	2.144735e-5
GO:0031223	auditory behavior	2.160123e-5
GO:0046110	xanthine metabolic process	2.285577e-5
GO:0034516	response to vitamin B6	2.314490e-5
GO:0043420	anthranilate metabolic process	2.314490e-5
GO:0002699	positive regulation of immune effector process	2.468165e-5
GO:0006810	transport	2.627570e-5
GO:0002684	positive regulation of immune system process	3.159701e-5
GO:0019805	quinolinate biosynthetic process	3.425706e-5
GO:0050854	regulation of antigen receptor-mediated signaling pathway	3.743425e-5
GO:0010886	positive regulation of cholesterol storage	4.082156e-5
GO:0009260	ribonucleotide biosynthetic process	4.106447e-5
GO:0060356	leucine import	4.182220e-5
GO:0002708	positive regulation of lymphocyte mediated immunity	4.294118e-5
GO:0031032	actomyosin structure organization	4.359282e-5
GO:0018125	peptidyl-cysteine methylation	4.512114e-5
GO:0031860	telomeric 3' overhang formation	4.512114e-5
GO:0060013	righting reflex	4.522476e-5
GO:0072560	type B pancreatic cell maturation	4.882674e-5
GO:0030239	myofibril assembly	5.022845e-5
GO:2000121	regulation of removal of superoxide radicals	5.069351e-5
GO:0002024	diet induced thermogenesis	5.155886e-5
GO:0009566	fertilization	5.365804e-5
GO:0034654	nucleobase-containing compound biosynthetic process	5.535896e-5
GO:0006145	purine base catabolic process	6.687354e-5
GO:0007638	mechanosensory behavior	7.536109e-5
GO:0007286	spermatid development	7.792390e-5
GO:0050896	response to stimulus	8.223463e-5
GO:0009152	purine ribonucleotide biosynthetic process	8.331821e-5
GO:0044281	small molecule metabolic process	8.356572e-5
GO:0001101	response to acid	8.476282e-5
GO:0034421	post-translational protein acetylation	9.076283e-5
GO:0050766	positive regulation of phagocytosis	9.296609e-5
GO:0010883	regulation of lipid storage	9.686963e-5
GO:0031295	T cell costimulation	9.717827e-5
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.717827e-5
GO:0002921	negative regulation of humoral immune response	9.874167e-5
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	9.950799e-5
GO:0007512	adult heart development	1.078354e-4
GO:2000334	positive regulation of blood microparticle formation	1.090402e-4
GO:0015827	tryptophan transport	1.090402e-4
GO:0021756	striatum development	1.112703e-4
GO:0002675	positive regulation of acute inflammatory response	1.112703e-4
GO:0050764	regulation of phagocytosis	1.161471e-4
GO:0021544	subpallium development	1.212183e-4
GO:0006098	pentose-phosphate shunt	1.270171e-4
GO:0043200	response to amino acid stimulus	1.298709e-4
GO:0042990	regulation of transcription factor import into nucleus	1.368430e-4
GO:0010575	positive regulation vascular endothelial growth factor production	1.564343e-4
GO:0010927	cellular component assembly involved in morphogenesis	1.597951e-4
GO:0043589	skin morphogenesis	1.604903e-4
GO:0051234	establishment of localization	1.667644e-4
GO:0009124	nucleoside monophosphate biosynthetic process	1.682188e-4
GO:0010884	positive regulation of lipid storage	1.691597e-4
GO:0009074	aromatic amino acid family catabolic process	1.718095e-4
GO:0007595	lactation	1.793659e-4
GO:0055096	low-density lipoprotein particle mediated signaling	1.808621e-4
GO:0002820	negative regulation of adaptive immune response	1.867131e-4
GO:0045345	positive regulation of MHC class I biosynthetic process	1.955048e-4
GO:0070543	response to linoleic acid	1.955048e-4
GO:0034696	response to prostaglandin F stimulus	1.955048e-4
GO:0034014	response to triglyceride	1.955048e-4
GO:0006954	inflammatory response	2.015656e-4
GO:0009113	purine base biosynthetic process	2.020969e-4
GO:0043506	regulation of JUN kinase activity	2.027889e-4
GO:0042346	positive regulation of NF-kappaB import into nucleus	2.316694e-4
GO:0019439	aromatic compound catabolic process	2.354069e-4
GO:0055002	striated muscle cell development	2.380978e-4
GO:0051716	cellular response to stimulus	2.413127e-4
GO:0050856	regulation of T cell receptor signaling pathway	2.535435e-4
GO:0046942	carboxylic acid transport	2.558024e-4
GO:0071447	cellular response to hydroperoxide	2.743847e-4
GO:0015911	plasma membrane long-chain fatty acid transport	2.743847e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2.849020e-4
GO:0034694	response to prostaglandin stimulus	2.950787e-4
GO:0045214	sarcomere organization	2.958203e-4
GO:0070371	ERK1 and ERK2 cascade	3.158686e-4
GO:0006457	protein folding	3.161849e-4
GO:0018208	peptidyl-proline modification	3.329152e-4
GO:0033194	response to hydroperoxide	3.544110e-4
GO:0046496	nicotinamide nucleotide metabolic process	3.619232e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	3.674441e-4
GO:0060135	maternal process involved in female pregnancy	3.691888e-4
GO:0048515	spermatid differentiation	3.748537e-4
GO:0042345	regulation of NF-kappaB import into nucleus	3.991389e-4
GO:0015849	organic acid transport	4.024920e-4
GO:0060100	positive regulation of phagocytosis, engulfment	4.070747e-4
GO:2000078	positive regulation of type B pancreatic cell development	4.431784e-4
GO:0034383	low-density lipoprotein particle clearance	4.472397e-4
GO:0006563	L-serine metabolic process	4.535084e-4
GO:0048840	otolith development	4.605560e-4
GO:0015820	leucine transport	4.605560e-4
GO:0010951	negative regulation of endopeptidase activity	4.606356e-4
GO:0010885	regulation of cholesterol storage	4.696841e-4
GO:0023052	signaling	4.758854e-4
GO:0006959	humoral immune response	4.849286e-4
GO:0043588	skin development	4.951264e-4
GO:0018130	heterocycle biosynthetic process	5.094969e-4
GO:0090074	negative regulation of protein homodimerization activity	5.294115e-4
GO:0014075	response to amine stimulus	5.531043e-4
GO:0043687	post-translational protein modification	5.639634e-4
GO:0042267	natural killer cell mediated cytotoxicity	5.639634e-4
GO:0060004	reflex	5.647190e-4
GO:0046622	positive regulation of organ growth	5.665216e-4
GO:0048857	neural nucleus development	5.665216e-4
GO:0050853	B cell receptor signaling pathway	5.712784e-4
GO:0019321	pentose metabolic process	5.714121e-4
GO:0003350	pulmonary myocardium development	5.905966e-4
GO:0015833	peptide transport	6.222344e-4
GO:0048245	eosinophil chemotaxis	6.269294e-4
GO:0030422	production of siRNA involved in RNA interference	6.269294e-4
GO:0006432	phenylalanyl-tRNA aminoacylation	6.269294e-4
GO:0043507	positive regulation of JUN kinase activity	6.276585e-4
GO:0010243	response to organic nitrogen	6.427753e-4
GO:0044271	cellular nitrogen compound biosynthetic process	6.744375e-4
GO:0031627	telomeric loop formation	6.906394e-4
GO:0007179	transforming growth factor beta receptor signaling pathway	6.947530e-4
GO:0002720	positive regulation of cytokine production involved in immune response	7.139905e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	7.287948e-4
GO:0002021	response to dietary excess	7.631886e-4
GO:0001954	positive regulation of cell-matrix adhesion	7.682023e-4
GO:0030072	peptide hormone secretion	7.755383e-4
GO:0010743	regulation of macrophage derived foam cell differentiation	7.908963e-4
GO:0055001	muscle cell development	8.291703e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	8.540090e-4
GO:0010574	regulation of vascular endothelial growth factor production	8.555134e-4
GO:0045343	regulation of MHC class I biosynthetic process	8.589904e-4
GO:0016246	RNA interference	8.589904e-4
GO:0042993	positive regulation of transcription factor import into nucleus	8.829155e-4
GO:0043090	amino acid import	8.844877e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	8.914887e-4
GO:0019346	transsulfuration	9.094336e-4
GO:0019343	cysteine biosynthetic process via cystathionine	9.094336e-4
GO:0043418	homocysteine catabolic process	9.094336e-4
GO:0006535	cysteine biosynthetic process from serine	9.094336e-4
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	9.094336e-4
GO:0046903	secretion	9.166434e-4
GO:0002250	adaptive immune response	9.271068e-4
GO:0050851	antigen receptor-mediated signaling pathway	9.275331e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	9.346968e-4
GO:0007589	body fluid secretion	9.375306e-4
GO:0006725	cellular aromatic compound metabolic process	9.518661e-4
GO:0044062	regulation of excretion	9.524146e-4
GO:0019448	L-cysteine catabolic process	9.951271e-4
GO:0009435	NAD biosynthetic process	1.043607e-3
GO:0055007	cardiac muscle cell differentiation	1.067704e-3
GO:0035051	cardiac cell differentiation	1.112095e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.125511e-3
GO:0046951	ketone body biosynthetic process	1.145732e-3
GO:0002673	regulation of acute inflammatory response	1.159484e-3
GO:0002125	maternal aggressive behavior	1.167616e-3
GO:0009117	nucleotide metabolic process	1.187172e-3
GO:0015031	protein transport	1.212757e-3
GO:0002790	peptide secretion	1.254963e-3
GO:0009156	ribonucleoside monophosphate biosynthetic process	1.294015e-3
GO:0009954	proximal/distal pattern formation	1.303762e-3
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	1.309231e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	1.311603e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.312055e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.351363e-3
GO:0046483	heterocycle metabolic process	1.371478e-3
GO:0050433	regulation of catecholamine secretion	1.389974e-3
GO:0060742	epithelial cell differentiation involved in prostate gland development	1.390626e-3
GO:0030073	insulin secretion	1.412229e-3
GO:0007015	actin filament organization	1.416111e-3
GO:0019376	galactolipid catabolic process	1.457304e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	1.462198e-3
GO:0003008	system process	1.464546e-3
GO:0046103	inosine biosynthetic process	1.467660e-3
GO:0006154	adenosine catabolic process	1.467660e-3
GO:0060285	ciliary cell motility	1.493534e-3
GO:0035095	behavioral response to nicotine	1.493534e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	1.503335e-3
GO:0002683	negative regulation of immune system process	1.516671e-3
GO:0003084	positive regulation of systemic arterial blood pressure	1.562734e-3
GO:0009259	ribonucleotide metabolic process	1.606233e-3
GO:0021549	cerebellum development	1.616760e-3
GO:0060112	generation of ovulation cycle rhythm	1.630069e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.630069e-3
GO:0007165	signal transduction	1.635044e-3
GO:0009123	nucleoside monophosphate metabolic process	1.648682e-3
GO:0071402	cellular response to lipoprotein particle stimulus	1.725033e-3
GO:0055086	nucleobase-containing small molecule metabolic process	1.732454e-3
GO:0001508	regulation of action potential	1.815936e-3
GO:0014866	skeletal myofibril assembly	1.847835e-3
GO:0019362	pyridine nucleotide metabolic process	1.923440e-3
GO:0002697	regulation of immune effector process	1.925876e-3
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1.970675e-3
GO:0007154	cell communication	2.058965e-3
GO:0035813	regulation of renal sodium excretion	2.061668e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	2.090391e-3
GO:0043206	fibril organization	2.102975e-3
GO:0007264	small GTPase mediated signal transduction	2.115877e-3
GO:0045577	regulation of B cell differentiation	2.131281e-3
GO:0009112	nucleobase metabolic process	2.131281e-3
GO:0002682	regulation of immune system process	2.143593e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	2.202454e-3
GO:0070814	hydrogen sulfide biosynthetic process	2.202454e-3
GO:0046102	inosine metabolic process	2.202454e-3
GO:0009070	serine family amino acid biosynthetic process	2.292536e-3
GO:0009150	purine ribonucleotide metabolic process	2.321124e-3
GO:0006869	lipid transport	2.351082e-3
GO:0006566	threonine metabolic process	2.397577e-3
GO:0048469	cell maturation	2.416483e-3
GO:0070613	regulation of protein processing	2.521505e-3
GO:0006040	amino sugar metabolic process	2.556697e-3
GO:0006260	DNA replication	2.633499e-3
GO:0071985	multivesicular body sorting pathway	2.641388e-3
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	2.641388e-3
GO:0046112	nucleobase biosynthetic process	2.675585e-3
GO:0043624	cellular protein complex disassembly	2.675585e-3
GO:0060627	regulation of vesicle-mediated transport	2.677081e-3
GO:0070899	mitochondrial tRNA wobble uridine modification	2.686701e-3
GO:0019374	galactolipid metabolic process	2.700135e-3
GO:0045830	positive regulation of isotype switching	2.703780e-3
GO:0002757	immune response-activating signal transduction	2.740635e-3
GO:0019835	cytolysis	2.755420e-3
GO:0006706	steroid catabolic process	2.755420e-3
GO:0000413	protein peptidyl-prolyl isomerization	2.761303e-3
GO:0006835	dicarboxylic acid transport	2.764604e-3
GO:0006739	NADP metabolic process	2.811529e-3
GO:0071221	cellular response to bacterial lipopeptide	2.825206e-3
GO:0044273	sulfur compound catabolic process	2.966195e-3
GO:0008152	metabolic process	3.000623e-3
GO:0006565	L-serine catabolic process	3.130565e-3
GO:0006811	ion transport	3.146474e-3
GO:0006163	purine nucleotide metabolic process	3.287241e-3
GO:0046634	regulation of alpha-beta T cell activation	3.410553e-3
GO:0006955	immune response	3.419171e-3
GO:0050729	positive regulation of inflammatory response	3.471149e-3
GO:2000379	positive regulation of reactive oxygen species metabolic process	3.486116e-3
GO:0071216	cellular response to biotic stimulus	3.508877e-3
GO:0032891	negative regulation of organic acid transport	3.559685e-3
GO:0046466	membrane lipid catabolic process	3.577508e-3
GO:0009072	aromatic amino acid family metabolic process	3.577508e-3
GO:0043241	protein complex disassembly	3.587185e-3
GO:0044130	negative regulation of growth of symbiont in host	3.592240e-3
GO:0044242	cellular lipid catabolic process	3.601906e-3
GO:0007527	adult somatic muscle development	3.620550e-3
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	3.620550e-3
GO:0010046	response to mycotoxin	3.671726e-3
GO:0009791	post-embryonic development	3.717922e-3
GO:0001502	cartilage condensation	3.844555e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	4.012652e-3
GO:0022037	metencephalon development	4.114236e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	4.123135e-3
GO:0045911	positive regulation of DNA recombination	4.160495e-3
GO:0048730	epidermis morphogenesis	4.234324e-3
GO:0072521	purine-containing compound metabolic process	4.292927e-3
GO:0002764	immune response-regulating signaling pathway	4.298285e-3
GO:0021707	cerebellar granule cell differentiation	4.332114e-3
GO:0009201	ribonucleoside triphosphate biosynthetic process	4.354768e-3
GO:0003341	cilium movement	4.366418e-3
GO:0002711	positive regulation of T cell mediated immunity	4.378424e-3
GO:0045184	establishment of protein localization	4.460336e-3
GO:0002700	regulation of production of molecular mediator of immune response	4.480369e-3
GO:0002726	positive regulation of T cell cytokine production	4.498607e-3
GO:0019441	tryptophan catabolic process to kynurenine	4.629731e-3
GO:0046635	positive regulation of alpha-beta T cell activation	4.689583e-3
GO:0002067	glandular epithelial cell differentiation	4.717562e-3
GO:0007613	memory	4.720806e-3
GO:0050667	homocysteine metabolic process	4.775416e-3
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	4.775416e-3
GO:0010817	regulation of hormone levels	4.868067e-3
GO:0034224	cellular response to zinc ion starvation	4.916325e-3
GO:0019240	citrulline biosynthetic process	4.916325e-3
GO:0046328	regulation of JNK cascade	4.921002e-3
GO:0090322	regulation of superoxide metabolic process	4.929364e-3
GO:0009161	ribonucleoside monophosphate metabolic process	4.941344e-3
GO:0042953	lipoprotein transport	5.013602e-3
GO:0046879	hormone secretion	5.186370e-3
GO:0045618	positive regulation of keratinocyte differentiation	5.209359e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	5.221727e-3
GO:0015807	L-amino acid transport	5.221727e-3
GO:0015711	organic anion transport	5.225858e-3
GO:0010871	negative regulation of receptor biosynthetic process	5.258574e-3
GO:0009914	hormone transport	5.462260e-3
GO:0071896	protein localization to adherens junction	5.518085e-3
GO:0048732	gland development	5.561874e-3
GO:0034143	regulation of toll-like receptor 4 signaling pathway	5.607755e-3
GO:0009145	purine nucleoside triphosphate biosynthetic process	5.616495e-3
GO:0006572	tyrosine catabolic process	5.668904e-3
GO:0046950	cellular ketone body metabolic process	5.668904e-3
GO:0006865	amino acid transport	5.709022e-3
GO:0006029	proteoglycan metabolic process	5.745657e-3
GO:0050864	regulation of B cell activation	5.780325e-3
GO:0021683	cerebellar granular layer morphogenesis	5.966151e-3
GO:0032793	positive regulation of CREB transcription factor activity	5.966151e-3
GO:0034381	plasma lipoprotein particle clearance	5.974416e-3
GO:0030198	extracellular matrix organization	5.992582e-3
GO:0032844	regulation of homeostatic process	5.993607e-3
GO:0070206	protein trimerization	6.003635e-3
GO:0021700	developmental maturation	6.097454e-3
GO:0002439	chronic inflammatory response to antigenic stimulus	6.154693e-3
GO:0031848	protection from non-homologous end joining at telomere	6.386591e-3
GO:0045061	thymic T cell selection	6.403485e-3
GO:0046320	regulation of fatty acid oxidation	6.543627e-3
GO:0010460	positive regulation of heart rate	6.543627e-3
GO:0046321	positive regulation of fatty acid oxidation	6.551902e-3
GO:0043901	negative regulation of multi-organism process	6.591068e-3
GO:0030903	notochord development	6.617968e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	6.617968e-3
GO:0010172	embryonic body morphogenesis	6.617968e-3
GO:0006733	oxidoreduction coenzyme metabolic process	6.717106e-3
GO:0000018	regulation of DNA recombination	6.717383e-3
GO:0018195	peptidyl-arginine modification	6.727945e-3
GO:0035556	intracellular signal transduction	6.734010e-3
GO:0016042	lipid catabolic process	6.752145e-3
GO:0006044	N-acetylglucosamine metabolic process	6.787614e-3
GO:0006887	exocytosis	6.791926e-3
GO:0046039	GTP metabolic process	6.826412e-3
GO:0032680	regulation of tumor necrosis factor production	6.827261e-3
GO:0032760	positive regulation of tumor necrosis factor production	6.928177e-3
GO:0034220	ion transmembrane transport	6.934923e-3
GO:0045923	positive regulation of fatty acid metabolic process	7.013274e-3
GO:0006013	mannose metabolic process	7.054169e-3
GO:0007257	activation of JUN kinase activity	7.129797e-3
GO:0019935	cyclic-nucleotide-mediated signaling	7.134044e-3
GO:0009142	nucleoside triphosphate biosynthetic process	7.165618e-3
GO:0031998	regulation of fatty acid beta-oxidation	7.170977e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	7.207484e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	7.209400e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	7.209400e-3
GO:0048936	peripheral nervous system neuron axonogenesis	7.276329e-3
GO:0000963	mitochondrial RNA processing	7.276329e-3
GO:0045191	regulation of isotype switching	7.385960e-3
GO:0006171	cAMP biosynthetic process	7.459964e-3
GO:0045807	positive regulation of endocytosis	7.691579e-3
GO:0050878	regulation of body fluid levels	7.704032e-3
GO:0045606	positive regulation of epidermal cell differentiation	7.775684e-3
GO:0034121	regulation of toll-like receptor signaling pathway	7.795013e-3
GO:0002886	regulation of myeloid leukocyte mediated immunity	7.972570e-3
GO:0033523	histone H2B ubiquitination	7.991294e-3
GO:0010876	lipid localization	8.001371e-3
GO:0042446	hormone biosynthetic process	8.079896e-3
GO:0022616	DNA strand elongation	8.092064e-3
GO:0008203	cholesterol metabolic process	8.100491e-3
GO:0060174	limb bud formation	8.170292e-3
GO:0032673	regulation of interleukin-4 production	8.170292e-3
GO:0043277	apoptotic cell clearance	8.187391e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	8.190237e-3
GO:0006694	steroid biosynthetic process	8.267261e-3
GO:0030240	skeletal muscle thin filament assembly	8.378593e-3
GO:0014048	regulation of glutamate secretion	8.418735e-3
GO:0050870	positive regulation of T cell activation	8.420232e-3
GO:0030879	mammary gland development	8.708356e-3
GO:0014706	striated muscle tissue development	8.711310e-3
GO:0071223	cellular response to lipoteichoic acid	8.920387e-3
GO:0006568	tryptophan metabolic process	8.920387e-3
GO:0046085	adenosine metabolic process	8.920387e-3
GO:0035815	positive regulation of renal sodium excretion	8.998556e-3
GO:0051639	actin filament network formation	9.035509e-3
GO:0046395	carboxylic acid catabolic process	9.095896e-3
GO:0050679	positive regulation of epithelial cell proliferation	9.099641e-3
GO:0070918	production of small RNA involved in gene silencing by RNA	9.255802e-3
GO:0070189	kynurenine metabolic process	9.411750e-3
GO:0032769	negative regulation of monooxygenase activity	9.411750e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	9.595840e-3
GO:0007608	sensory perception of smell	9.656262e-3
GO:0055098	response to low-density lipoprotein particle stimulus	9.665406e-3
GO:0034122	negative regulation of toll-like receptor signaling pathway	9.665406e-3
GO:0014059	regulation of dopamine secretion	9.665406e-3
GO:0006910	phagocytosis, recognition	9.729366e-3
GO:0060525	prostate glandular acinus development	9.748104e-3
GO:0012502	induction of programmed cell death	9.957534e-3
GO:0006909	phagocytosis	1.001609e-2
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	1.003194e-2
GO:0042713	sperm ejaculation	1.004056e-2
GO:0003309	type B pancreatic cell differentiation	1.008775e-2
GO:0080135	regulation of cellular response to stress	1.012373e-2
GO:0050996	positive regulation of lipid catabolic process	1.013139e-2
GO:0050863	regulation of T cell activation	1.026461e-2
GO:0006352	transcription initiation, DNA-dependent	1.033252e-2
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	1.034032e-2
GO:0009448	gamma-aminobutyric acid metabolic process	1.034032e-2
GO:0006613	cotranslational protein targeting to membrane	1.034032e-2
GO:0001909	leukocyte mediated cytotoxicity	1.046130e-2
GO:0050852	T cell receptor signaling pathway	1.073139e-2
GO:0009167	purine ribonucleoside monophosphate metabolic process	1.092080e-2
GO:0016098	monoterpenoid metabolic process	1.110794e-2
GO:0048302	regulation of isotype switching to IgG isotypes	1.114407e-2
GO:0007274	neuromuscular synaptic transmission	1.114407e-2
GO:0045616	regulation of keratinocyte differentiation	1.114407e-2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	1.123244e-2
GO:0017157	regulation of exocytosis	1.133892e-2
GO:0006754	ATP biosynthetic process	1.137345e-2
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.144249e-2
GO:0006983	ER overload response	1.163306e-2
GO:0008202	steroid metabolic process	1.177970e-2
GO:0009199	ribonucleoside triphosphate metabolic process	1.179644e-2
GO:0000733	DNA strand renaturation	1.180505e-2
GO:0006559	L-phenylalanine catabolic process	1.180505e-2
GO:0006702	androgen biosynthetic process	1.190853e-2
GO:0021575	hindbrain morphogenesis	1.198855e-2
GO:0045780	positive regulation of bone resorption	1.200878e-2
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1.204391e-2
GO:0003180	aortic valve morphogenesis	1.214919e-2
GO:0051056	regulation of small GTPase mediated signal transduction	1.218011e-2
GO:0060749	mammary gland alveolus development	1.219612e-2
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.223828e-2
GO:0007499	ectoderm and mesoderm interaction	1.223828e-2
GO:0032753	positive regulation of interleukin-4 production	1.239756e-2
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.246511e-2
GO:0009069	serine family amino acid metabolic process	1.253158e-2
GO:0006564	L-serine biosynthetic process	1.258470e-2
GO:0072086	specification of loop of Henle identity	1.258470e-2
GO:0000959	mitochondrial RNA metabolic process	1.258470e-2
GO:0051179	localization	1.275106e-2
GO:0006917	induction of apoptosis	1.301561e-2
GO:0007166	cell surface receptor linked signaling pathway	1.307364e-2
GO:0051952	regulation of amine transport	1.318030e-2
GO:0032846	positive regulation of homeostatic process	1.326947e-2
GO:0046058	cAMP metabolic process	1.327804e-2
GO:0060537	muscle tissue development	1.332798e-2
GO:0032768	regulation of monooxygenase activity	1.335419e-2
GO:0006534	cysteine metabolic process	1.338068e-2
GO:0021681	cerebellar granular layer development	1.338068e-2
GO:0006558	L-phenylalanine metabolic process	1.339647e-2
GO:0046340	diacylglycerol catabolic process	1.343214e-2
GO:0019344	cysteine biosynthetic process	1.343214e-2
GO:0030046	parallel actin filament bundle assembly	1.343214e-2