Novel motif:28

name:	motif28_CGTNCA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0045717	negative regulation of fatty acid biosynthetic process	3.733468e-14
GO:0002679	respiratory burst involved in defense response	6.798469e-14
GO:0032425	positive regulation of mismatch repair	5.641857e-13
GO:0045922	negative regulation of fatty acid metabolic process	1.072069e-12
GO:0051055	negative regulation of lipid biosynthetic process	5.340318e-12
GO:0002149	hypochlorous acid biosynthetic process	2.728592e-11
GO:0070593	dendrite self-avoidance	2.884488e-10
GO:0010987	negative regulation of high-density lipoprotein particle clearance	7.245543e-10
GO:0010897	negative regulation of triglyceride catabolic process	7.245543e-10
GO:0051324	prophase	1.168052e-9
GO:0006544	glycine metabolic process	1.416375e-9
GO:0008033	tRNA processing	4.798926e-9
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	5.549923e-9
GO:0043491	protein kinase B signaling cascade	9.323696e-9
GO:0048842	positive regulation of axon extension involved in axon guidance	9.358775e-9
GO:0044319	wound healing, spreading of cells	9.899007e-9
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	1.394577e-8
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.628686e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.198124e-8
GO:0006853	carnitine shuttle	2.369855e-8
GO:0033326	cerebrospinal fluid secretion	2.388339e-8
GO:0007128	meiotic prophase I	2.442803e-8
GO:0032423	regulation of mismatch repair	2.570585e-8
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.873193e-8
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	2.952761e-8
GO:0085029	extracellular matrix assembly	4.274179e-8
GO:0048251	elastic fiber assembly	6.056817e-8
GO:0051084	'de novo' posttranslational protein folding	6.081851e-8
GO:0042304	regulation of fatty acid biosynthetic process	6.273020e-8
GO:0010625	positive regulation of Schwann cell proliferation	6.758248e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	7.371648e-8
GO:0071279	cellular response to cobalt ion	7.491433e-8
GO:0010637	negative regulation of mitochondrial fusion	7.491433e-8
GO:0010624	regulation of Schwann cell proliferation	8.675090e-8
GO:0035313	wound healing, spreading of epidermal cells	9.842609e-8
GO:0006360	transcription from RNA polymerase I promoter	1.745757e-7
GO:0010934	macrophage cytokine production	1.747450e-7
GO:0006458	'de novo' protein folding	2.375313e-7
GO:0006548	histidine catabolic process	2.681145e-7
GO:0042744	hydrogen peroxide catabolic process	3.863836e-7
GO:0045654	positive regulation of megakaryocyte differentiation	4.668258e-7
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	5.981314e-7
GO:0060710	chorio-allantoic fusion	6.965627e-7
GO:0045833	negative regulation of lipid metabolic process	7.828728e-7
GO:0090239	regulation of histone H4 acetylation	7.979181e-7
GO:0046890	regulation of lipid biosynthetic process	8.572866e-7
GO:0035691	macrophage migration inhibitory factor signaling pathway	8.841879e-7
GO:0017187	peptidyl-glutamic acid carboxylation	8.861970e-7
GO:0009069	serine family amino acid metabolic process	9.109268e-7
GO:0010544	negative regulation of platelet activation	9.841139e-7
GO:0009071	serine family amino acid catabolic process	1.015105e-6
GO:0051005	negative regulation of lipoprotein lipase activity	1.141827e-6
GO:0045556	positive regulation of TRAIL biosynthetic process	2.091135e-6
GO:0007283	spermatogenesis	2.605487e-6
GO:0071072	negative regulation of phospholipid biosynthetic process	2.711488e-6
GO:0010985	negative regulation of lipoprotein particle clearance	2.786334e-6
GO:0009070	serine family amino acid biosynthetic process	3.201900e-6
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	3.590683e-6
GO:0071071	regulation of phospholipid biosynthetic process	3.726856e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	3.757629e-6
GO:0071034	CUT catabolic process	3.937510e-6
GO:0043206	fibril organization	4.094278e-6
GO:0090241	negative regulation of histone H4 acetylation	4.804362e-6
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	4.804362e-6
GO:0032971	regulation of muscle filament sliding	4.981619e-6
GO:0034969	histone arginine methylation	5.313166e-6
GO:0007635	chemosensory behavior	5.812276e-6
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5.992475e-6
GO:0050434	positive regulation of viral transcription	6.074878e-6
GO:0060252	positive regulation of glial cell proliferation	6.478071e-6
GO:0006545	glycine biosynthetic process	6.580953e-6
GO:0010511	regulation of phosphatidylinositol biosynthetic process	6.653743e-6
GO:0006547	histidine metabolic process	6.959632e-6
GO:0045793	positive regulation of cell size	7.071715e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	7.931108e-6
GO:0006635	fatty acid beta-oxidation	8.445077e-6
GO:0018195	peptidyl-arginine modification	9.601444e-6
GO:0007506	gonadal mesoderm development	1.002833e-5
GO:0045112	integrin biosynthetic process	1.007131e-5
GO:0051788	response to misfolded protein	1.023860e-5
GO:0070979	protein K11-linked ubiquitination	1.026161e-5
GO:0006563	L-serine metabolic process	1.060889e-5
GO:0033590	response to cobalamin	1.131745e-5
GO:0006117	acetaldehyde metabolic process	1.131745e-5
GO:0045652	regulation of megakaryocyte differentiation	1.248592e-5
GO:0015879	carnitine transport	1.248592e-5
GO:0018216	peptidyl-arginine methylation	1.265583e-5
GO:0060689	cell differentiation involved in salivary gland development	1.353637e-5
GO:0071333	cellular response to glucose stimulus	1.382882e-5
GO:0048050	post-embryonic eye morphogenesis	1.431210e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.431210e-5
GO:0009235	cobalamin metabolic process	1.489223e-5
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.507146e-5
GO:0006430	lysyl-tRNA aminoacylation	1.535656e-5
GO:2000573	positive regulation of DNA biosynthetic process	1.575700e-5
GO:0006457	protein folding	1.641137e-5
GO:0046782	regulation of viral transcription	2.163155e-5
GO:0032094	response to food	2.205419e-5
GO:0008057	eye pigment granule organization	2.555124e-5
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	2.565202e-5
GO:0030277	maintenance of gastrointestinal epithelium	2.603784e-5
GO:0042093	T-helper cell differentiation	2.772769e-5
GO:0009886	post-embryonic morphogenesis	2.826533e-5
GO:0006399	tRNA metabolic process	2.952553e-5
GO:0006363	termination of RNA polymerase I transcription	2.960657e-5
GO:0070309	lens fiber cell morphogenesis	2.996751e-5
GO:0031284	positive regulation of guanylate cyclase activity	3.022723e-5
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.106173e-5
GO:0060020	Bergmann glial cell differentiation	3.142775e-5
GO:0006359	regulation of transcription from RNA polymerase III promoter	3.169401e-5
GO:0006424	glutamyl-tRNA aminoacylation	3.655703e-5
GO:0002440	production of molecular mediator of immune response	4.308038e-5
GO:0034633	retinol transport	4.379960e-5
GO:0071322	cellular response to carbohydrate stimulus	4.453638e-5
GO:0070301	cellular response to hydrogen peroxide	4.475945e-5
GO:0050769	positive regulation of neurogenesis	5.049809e-5
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	5.085072e-5
GO:0030198	extracellular matrix organization	5.108845e-5
GO:0043985	histone H4-R3 methylation	5.295183e-5
GO:0006685	sphingomyelin catabolic process	5.295183e-5
GO:0050803	regulation of synapse structure and activity	5.608266e-5
GO:0001878	response to yeast	5.646292e-5
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	5.971208e-5
GO:0070857	regulation of bile acid biosynthetic process	6.385839e-5
GO:2000210	positive regulation of anoikis	6.616360e-5
GO:0070307	lens fiber cell development	7.084350e-5
GO:0006422	aspartyl-tRNA aminoacylation	7.266669e-5
GO:0060251	regulation of glial cell proliferation	7.618785e-5
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	8.113304e-5
GO:0048524	positive regulation of viral reproduction	8.245281e-5
GO:0035246	peptidyl-arginine N-methylation	8.369321e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	9.163848e-5
GO:0006937	regulation of muscle contraction	9.208296e-5
GO:0030903	notochord development	9.221429e-5
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	9.238875e-5
GO:0048320	axial mesoderm formation	1.008217e-4
GO:0010984	regulation of lipoprotein particle clearance	1.032833e-4
GO:0051238	sequestering of metal ion	1.044346e-4
GO:0071218	cellular response to misfolded protein	1.136222e-4
GO:0045351	type I interferon biosynthetic process	1.158878e-4
GO:0031064	negative regulation of histone deacetylation	1.191169e-4
GO:0070345	negative regulation of fat cell proliferation	1.213431e-4
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.228607e-4
GO:0000239	pachytene	1.278958e-4
GO:0060713	labyrinthine layer morphogenesis	1.312798e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	1.320241e-4
GO:0045541	negative regulation of cholesterol biosynthetic process	1.427452e-4
GO:0010994	free ubiquitin chain polymerization	1.427452e-4
GO:0061077	chaperone-mediated protein folding	1.431058e-4
GO:0034470	ncRNA processing	1.459265e-4
GO:0019395	fatty acid oxidation	1.466863e-4
GO:0001970	positive regulation of activation of membrane attack complex	1.488455e-4
GO:0044089	positive regulation of cellular component biogenesis	1.497278e-4
GO:0060343	trabecula formation	1.579684e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	1.580475e-4
GO:0019254	carnitine metabolic process, CoA-linked	1.598454e-4
GO:0007623	circadian rhythm	1.614268e-4
GO:0090181	regulation of cholesterol metabolic process	1.624239e-4
GO:0043482	cellular pigment accumulation	1.663954e-4
GO:0043476	pigment accumulation	1.663954e-4
GO:0000086	G2/M transition of mitotic cell cycle	1.700814e-4
GO:0032964	collagen biosynthetic process	1.753557e-4
GO:0019217	regulation of fatty acid metabolic process	1.766015e-4
GO:0046724	oxalic acid secretion	1.801444e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	1.801444e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	1.809518e-4
GO:0032008	positive regulation of TOR signaling cascade	1.868414e-4
GO:0090257	regulation of muscle system process	1.972284e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	1.973310e-4
GO:0048561	establishment of organ orientation	1.979448e-4
GO:0046731	passive induction of host immune response by virus	1.979448e-4
GO:0032212	positive regulation of telomere maintenance via telomerase	2.079494e-4
GO:0010720	positive regulation of cell development	2.112048e-4
GO:0008286	insulin receptor signaling pathway	2.115107e-4
GO:0042376	phylloquinone catabolic process	2.121634e-4
GO:0032074	negative regulation of nuclease activity	2.121634e-4
GO:0032474	otolith morphogenesis	2.121634e-4
GO:0061003	positive regulation of dendritic spine morphogenesis	2.147758e-4
GO:0002536	respiratory burst involved in inflammatory response	2.155066e-4
GO:0048319	axial mesoderm morphogenesis	2.287697e-4
GO:0048706	embryonic skeletal system development	2.288317e-4
GO:0070198	protein localization to chromosome, telomeric region	2.378785e-4
GO:0051965	positive regulation of synapse assembly	2.395110e-4
GO:0035088	establishment or maintenance of apical/basal cell polarity	2.467295e-4
GO:0014040	positive regulation of Schwann cell differentiation	2.489336e-4
GO:0001678	cellular glucose homeostasis	2.498233e-4
GO:0009749	response to glucose stimulus	2.503252e-4
GO:0060561	apoptosis involved in morphogenesis	2.542616e-4
GO:0060041	retina development in camera-type eye	2.571322e-4
GO:0060711	labyrinthine layer development	2.601431e-4
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	2.601911e-4
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	2.726783e-4
GO:0035470	positive regulation of vascular wound healing	2.726783e-4
GO:0006546	glycine catabolic process	2.744234e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	2.771282e-4
GO:0002645	positive regulation of tolerance induction	2.812382e-4
GO:0031929	TOR signaling cascade	2.960248e-4
GO:0006880	intracellular sequestering of iron ion	2.989459e-4
GO:0034379	very-low-density lipoprotein particle assembly	3.243514e-4
GO:0006298	mismatch repair	3.288044e-4
GO:0035883	enteroendocrine cell differentiation	3.406066e-4
GO:0061383	trabecula morphogenesis	3.436765e-4
GO:0006555	methionine metabolic process	3.460603e-4
GO:0090209	negative regulation of triglyceride metabolic process	3.558562e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	3.558562e-4
GO:0009746	response to hexose stimulus	3.598006e-4
GO:0018200	peptidyl-glutamic acid modification	3.734871e-4
GO:0034284	response to monosaccharide stimulus	3.942030e-4
GO:0034447	very-low-density lipoprotein particle clearance	4.068007e-4
GO:0014813	satellite cell commitment	4.091817e-4
GO:0045820	negative regulation of glycolysis	4.110939e-4
GO:0090009	primitive streak formation	4.166176e-4
GO:0035247	peptidyl-arginine omega-N-methylation	4.199479e-4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	4.214109e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	4.280332e-4
GO:0019430	removal of superoxide radicals	4.280739e-4
GO:0032006	regulation of TOR signaling cascade	4.303168e-4
GO:0001839	neural plate morphogenesis	4.348630e-4
GO:0015670	carbon dioxide transport	4.398223e-4
GO:0060166	olfactory pit development	4.417375e-4
GO:0048515	spermatid differentiation	4.434615e-4
GO:0006471	protein ADP-ribosylation	4.486767e-4
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	4.537208e-4
GO:0005981	regulation of glycogen catabolic process	4.596437e-4
GO:0010894	negative regulation of steroid biosynthetic process	4.616813e-4
GO:0019542	propionate biosynthetic process	4.784758e-4
GO:0019413	acetate biosynthetic process	4.784758e-4
GO:0045109	intermediate filament organization	5.007692e-4
GO:0014740	negative regulation of muscle hyperplasia	5.121045e-4
GO:0032000	positive regulation of fatty acid beta-oxidation	5.254715e-4
GO:0060349	bone morphogenesis	5.277103e-4
GO:0051298	centrosome duplication	5.395541e-4
GO:0032025	response to cobalt ion	5.875388e-4
GO:0048146	positive regulation of fibroblast proliferation	6.007603e-4
GO:0008210	estrogen metabolic process	6.134619e-4
GO:2000209	regulation of anoikis	6.151028e-4
GO:0006821	chloride transport	6.400265e-4
GO:0046015	regulation of transcription by glucose	6.594619e-4
GO:0032606	type I interferon production	6.594619e-4
GO:0006282	regulation of DNA repair	6.770033e-4
GO:0006564	L-serine biosynthetic process	6.995853e-4
GO:0046599	regulation of centriole replication	6.997509e-4
GO:0043923	positive regulation by host of viral transcription	7.091855e-4
GO:0006760	folic acid-containing compound metabolic process	7.114282e-4
GO:0055114	oxidation-reduction process	7.329266e-4
GO:0045939	negative regulation of steroid metabolic process	7.338698e-4
GO:0006565	L-serine catabolic process	7.457080e-4
GO:0042073	intraflagellar transport	7.743992e-4
GO:0042758	long-chain fatty acid catabolic process	7.743992e-4
GO:0042413	carnitine catabolic process	7.743992e-4
GO:0070922	small RNA loading onto RISC	7.811210e-4
GO:0030047	actin modification	7.811210e-4
GO:0031282	regulation of guanylate cyclase activity	7.868194e-4
GO:0061144	alveolar secondary septum development	7.904271e-4
GO:0060691	epithelial cell maturation involved in salivary gland development	7.904271e-4
GO:0060096	serotonin secretion, neurotransmission	7.904271e-4
GO:0000303	response to superoxide	7.958180e-4
GO:0060347	heart trabecula formation	8.016452e-4
GO:0002579	positive regulation of antigen processing and presentation	8.047663e-4
GO:0009062	fatty acid catabolic process	8.077279e-4
GO:0045064	T-helper 2 cell differentiation	8.198889e-4
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	8.198889e-4
GO:0002315	marginal zone B cell differentiation	8.198889e-4
GO:0045338	farnesyl diphosphate metabolic process	8.221401e-4
GO:0032369	negative regulation of lipid transport	8.234978e-4
GO:0032792	negative regulation of CREB transcription factor activity	8.250945e-4
GO:0034440	lipid oxidation	8.421670e-4
GO:0009637	response to blue light	8.444052e-4
GO:0090150	establishment of protein localization in membrane	8.472026e-4
GO:0050807	regulation of synapse organization	8.485390e-4
GO:0071670	smooth muscle cell chemotaxis	8.496179e-4
GO:0072553	terminal button organization	8.496179e-4
GO:0060981	cell migration involved in coronary angiogenesis	8.496179e-4
GO:0016233	telomere capping	8.534286e-4
GO:0046320	regulation of fatty acid oxidation	8.556805e-4
GO:0043467	regulation of generation of precursor metabolites and energy	8.619914e-4
GO:0033574	response to testosterone stimulus	8.729497e-4
GO:0002066	columnar/cuboidal epithelial cell development	9.034500e-4
GO:0040015	negative regulation of multicellular organism growth	9.151945e-4
GO:0048569	post-embryonic organ development	9.239000e-4
GO:0044027	hypermethylation of CpG island	9.369147e-4
GO:0090162	establishment of epithelial cell polarity	9.369147e-4
GO:0045909	positive regulation of vasodilation	9.401055e-4
GO:0042552	myelination	9.916275e-4
GO:0051919	positive regulation of fibrinolysis	1.024608e-3
GO:0060632	regulation of microtubule-based movement	1.035732e-3
GO:0010954	positive regulation of protein processing	1.040998e-3
GO:0001936	regulation of endothelial cell proliferation	1.048341e-3
GO:0048318	axial mesoderm development	1.059729e-3
GO:0015747	urate transport	1.108880e-3
GO:0007386	compartment pattern specification	1.110268e-3
GO:0010189	vitamin E biosynthetic process	1.114077e-3
GO:0019218	regulation of steroid metabolic process	1.147375e-3
GO:0051591	response to cAMP	1.170010e-3
GO:0006171	cAMP biosynthetic process	1.175058e-3
GO:0051580	regulation of neurotransmitter uptake	1.182733e-3
GO:0031293	membrane protein intracellular domain proteolysis	1.204076e-3
GO:0006290	pyrimidine dimer repair	1.217954e-3
GO:0060621	negative regulation of cholesterol import	1.311240e-3
GO:0034614	cellular response to reactive oxygen species	1.314590e-3
GO:0048562	embryonic organ morphogenesis	1.319742e-3
GO:0009405	pathogenesis	1.345465e-3
GO:0001974	blood vessel remodeling	1.369627e-3
GO:0045739	positive regulation of DNA repair	1.374944e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	1.396128e-3
GO:0071732	cellular response to nitric oxide	1.403734e-3
GO:0018105	peptidyl-serine phosphorylation	1.428731e-3
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	1.458258e-3
GO:0045402	regulation of interleukin-4 biosynthetic process	1.469738e-3
GO:0060035	notochord cell development	1.487252e-3
GO:0006353	transcription termination, DNA-dependent	1.489263e-3
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.494839e-3
GO:0042823	pyridoxal phosphate biosynthetic process	1.535043e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	1.552747e-3
GO:0051725	protein de-ADP-ribosylation	1.554770e-3
GO:0043503	skeletal muscle fiber adaptation	1.564731e-3
GO:0048705	skeletal system morphogenesis	1.578684e-3
GO:0010669	epithelial structure maintenance	1.579272e-3
GO:0042866	pyruvate biosynthetic process	1.583126e-3
GO:0030890	positive regulation of B cell proliferation	1.585754e-3
GO:0032922	circadian regulation of gene expression	1.592709e-3
GO:0045063	T-helper 1 cell differentiation	1.594937e-3
GO:0070208	protein heterotrimerization	1.620748e-3
GO:0035176	social behavior	1.634215e-3
GO:0002577	regulation of antigen processing and presentation	1.643973e-3
GO:0002367	cytokine production involved in immune response	1.655102e-3
GO:0072329	monocarboxylic acid catabolic process	1.673866e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.694717e-3
GO:2000002	negative regulation of DNA damage checkpoint	1.694717e-3
GO:0021588	cerebellum formation	1.694717e-3
GO:0021551	central nervous system morphogenesis	1.694717e-3
GO:0007161	calcium-independent cell-matrix adhesion	1.694717e-3
GO:0006354	transcription elongation, DNA-dependent	1.698691e-3
GO:0006942	regulation of striated muscle contraction	1.734172e-3
GO:0008355	olfactory learning	1.746916e-3
GO:0051291	protein heterooligomerization	1.764887e-3
GO:0000305	response to oxygen radical	1.768655e-3
GO:0072593	reactive oxygen species metabolic process	1.770708e-3
GO:0035854	eosinophil fate commitment	1.798686e-3
GO:0030222	eosinophil differentiation	1.798686e-3
GO:0030823	regulation of cGMP metabolic process	1.808272e-3
GO:0007286	spermatid development	1.866202e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	1.899653e-3
GO:0032714	negative regulation of interleukin-5 production	1.976635e-3
GO:0097116	gephyrin clustering	1.978446e-3
GO:0035721	intraflagellar retrograde transport	1.986691e-3
GO:0001840	neural plate development	1.989249e-3
GO:0090311	regulation of protein deacetylation	2.079209e-3
GO:0042542	response to hydrogen peroxide	2.094051e-3
GO:0071233	cellular response to leucine	2.107621e-3
GO:0070914	UV-damage excision repair	2.107621e-3
GO:0018026	peptidyl-lysine monomethylation	2.110699e-3
GO:0051963	regulation of synapse assembly	2.213725e-3
GO:0000917	barrier septum formation	2.228265e-3
GO:0006400	tRNA modification	2.232306e-3
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.239860e-3
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	2.251260e-3
GO:0030953	astral microtubule organization	2.277604e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2.289288e-3
GO:0051101	regulation of DNA binding	2.343529e-3
GO:0085020	protein K6-linked ubiquitination	2.370010e-3
GO:0010458	exit from mitosis	2.370010e-3
GO:0001938	positive regulation of endothelial cell proliferation	2.403518e-3
GO:0007289	spermatid nucleus differentiation	2.429819e-3
GO:0034660	ncRNA metabolic process	2.461441e-3
GO:0032365	intracellular lipid transport	2.468629e-3
GO:0002366	leukocyte activation involved in immune response	2.472498e-3
GO:0007296	vitellogenesis	2.501507e-3
GO:0060033	anatomical structure regression	2.505898e-3
GO:0061384	heart trabecular morphogenesis	2.535851e-3
GO:0019884	antigen processing and presentation of exogenous antigen	2.535851e-3
GO:0070213	protein auto-ADP-ribosylation	2.559767e-3
GO:0014745	negative regulation of muscle adaptation	2.559767e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	2.575549e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	2.575549e-3
GO:0007371	ventral midline determination	2.575549e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	2.575549e-3
GO:0060620	regulation of cholesterol import	2.631468e-3
GO:0021592	fourth ventricle development	2.631468e-3
GO:0060409	positive regulation of acetylcholine metabolic process	2.637402e-3
GO:0002906	negative regulation of mature B cell apoptosis	2.638988e-3
GO:0031954	positive regulation of protein autophosphorylation	2.691219e-3
GO:0014002	astrocyte development	2.691219e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	2.695770e-3
GO:0046626	regulation of insulin receptor signaling pathway	2.736898e-3
GO:0006601	creatine biosynthetic process	2.759383e-3
GO:0014738	regulation of muscle hyperplasia	2.873057e-3
GO:0002067	glandular epithelial cell differentiation	2.888065e-3
GO:0060690	epithelial cell differentiation involved in salivary gland development	2.888981e-3
GO:0009785	blue light signaling pathway	2.922368e-3
GO:0050884	neuromuscular process controlling posture	2.940639e-3
GO:0048240	sperm capacitation	2.993484e-3
GO:0018209	peptidyl-serine modification	3.049707e-3
GO:0060872	semicircular canal development	3.052411e-3
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3.074013e-3
GO:0019730	antimicrobial humoral response	3.074013e-3
GO:0002268	follicular dendritic cell differentiation	3.074013e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	3.135772e-3
GO:0021526	medial motor column neuron differentiation	3.145966e-3
GO:0070734	histone H3-K27 methylation	3.145966e-3
GO:0003329	pancreatic PP cell fate commitment	3.145966e-3
GO:0003326	pancreatic A cell fate commitment	3.145966e-3
GO:0006283	transcription-coupled nucleotide-excision repair	3.188996e-3
GO:0048568	embryonic organ development	3.209179e-3
GO:0014015	positive regulation of gliogenesis	3.263331e-3
GO:0001892	embryonic placenta development	3.279194e-3
GO:0060999	positive regulation of dendritic spine development	3.282552e-3
GO:0032210	regulation of telomere maintenance via telomerase	3.282552e-3
GO:0016126	sterol biosynthetic process	3.350912e-3
GO:0033261	regulation of S phase	3.446483e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	3.592731e-3
GO:0032375	negative regulation of cholesterol transport	3.639338e-3
GO:0032205	negative regulation of telomere maintenance	3.649049e-3
GO:0006289	nucleotide-excision repair	3.770295e-3
GO:0006600	creatine metabolic process	3.801263e-3
GO:0006013	mannose metabolic process	3.844673e-3
GO:0050689	negative regulation of defense response to virus by host	3.851875e-3
GO:0009303	rRNA transcription	3.897908e-3
GO:0035587	purinergic receptor signaling pathway	3.911707e-3
GO:0051586	positive regulation of dopamine uptake	3.995564e-3
GO:0006884	cell volume homeostasis	4.027430e-3
GO:0006595	polyamine metabolic process	4.134825e-3
GO:0002426	immunoglobulin production in mucosal tissue	4.149202e-3
GO:0032933	SREBP-mediated signaling pathway	4.186335e-3
GO:0031998	regulation of fatty acid beta-oxidation	4.219691e-3
GO:0002902	regulation of B cell apoptosis	4.219691e-3
GO:0002275	myeloid cell activation involved in immune response	4.255288e-3
GO:2000278	regulation of DNA biosynthetic process	4.301288e-3
GO:0006386	termination of RNA polymerase III transcription	4.323167e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	4.323167e-3
GO:0071731	response to nitric oxide	4.362959e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	4.363936e-3
GO:0016075	rRNA catabolic process	4.363936e-3
GO:0097119	postsynaptic density protein 95 clustering	4.366137e-3
GO:0032206	positive regulation of telomere maintenance	4.366137e-3
GO:0097104	postsynaptic membrane assembly	4.366137e-3
GO:0008366	axon ensheathment	4.406373e-3
GO:0010565	regulation of cellular ketone metabolic process	4.436735e-3
GO:0019264	glycine biosynthetic process from serine	4.467411e-3
GO:0042113	B cell activation	4.636147e-3
GO:0016125	sterol metabolic process	4.640569e-3
GO:0007020	microtubule nucleation	4.665247e-3
GO:0090141	positive regulation of mitochondrial fission	4.691969e-3
GO:0035093	spermatogenesis, exchange of chromosomal proteins	4.691969e-3
GO:0061101	neuroendocrine cell differentiation	4.691969e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	4.737053e-3
GO:0001955	blood vessel maturation	4.739293e-3
GO:0060395	SMAD protein signal transduction	4.743002e-3
GO:0060438	trachea development	4.795522e-3
GO:0051349	positive regulation of lyase activity	4.866756e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	4.885533e-3
GO:0016246	RNA interference	4.906733e-3
GO:0030967	ER-nuclear sterol response pathway	4.945016e-3
GO:0090140	regulation of mitochondrial fission	4.949348e-3
GO:0070278	extracellular matrix constituent secretion	4.949348e-3
GO:0010260	organ senescence	4.949348e-3
GO:0000209	protein polyubiquitination	4.974362e-3
GO:0007141	male meiosis I	4.984040e-3
GO:2001014	regulation of skeletal muscle cell differentiation	4.993970e-3
GO:0000387	spliceosomal snRNP assembly	4.993970e-3
GO:0018027	peptidyl-lysine dimethylation	5.160535e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	5.177840e-3
GO:0097152	mesenchymal cell apoptosis	5.177840e-3
GO:0060982	coronary artery morphogenesis	5.177840e-3
GO:0035418	protein localization to synapse	5.212151e-3
GO:0060480	lung goblet cell differentiation	5.301913e-3
GO:0051289	protein homotetramerization	5.324026e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	5.334717e-3
GO:0010830	regulation of myotube differentiation	5.388998e-3
GO:0050772	positive regulation of axonogenesis	5.448298e-3
GO:0042360	vitamin E metabolic process	5.463138e-3
GO:0042048	olfactory behavior	5.463138e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	5.471042e-3
GO:0060348	bone development	5.493930e-3
GO:0048708	astrocyte differentiation	5.496407e-3
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	5.518767e-3
GO:0042396	phosphagen biosynthetic process	5.600713e-3
GO:0002377	immunoglobulin production	5.610953e-3
GO:0060764	cell-cell signaling involved in mammary gland development	5.625102e-3
GO:0034231	islet amyloid polypeptide processing	5.625102e-3
GO:0034230	enkephalin processing	5.625102e-3
GO:0000088	mitotic prophase	5.625102e-3
GO:0051973	positive regulation of telomerase activity	5.691777e-3
GO:0016090	prenol metabolic process	5.691777e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	5.713726e-3
GO:0032869	cellular response to insulin stimulus	5.786911e-3
GO:0035166	post-embryonic hemopoiesis	5.951353e-3
GO:0002666	positive regulation of T cell tolerance induction	5.952647e-3
GO:0051488	activation of anaphase-promoting complex activity	6.073302e-3
GO:0002636	positive regulation of germinal center formation	6.073302e-3
GO:0030195	negative regulation of blood coagulation	6.107967e-3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	6.146353e-3
GO:0046321	positive regulation of fatty acid oxidation	6.160988e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	6.201921e-3
GO:0048592	eye morphogenesis	6.261563e-3
GO:0070212	protein poly-ADP-ribosylation	6.339293e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	6.339293e-3
GO:0033119	negative regulation of RNA splicing	6.367872e-3
GO:0002792	negative regulation of peptide secretion	6.419270e-3
GO:0002830	positive regulation of type 2 immune response	6.448618e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0000305	response to oxygen radical	3.076057e-10
GO:0019430	removal of superoxide radicals	2.880696e-8
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.127007e-8
GO:0050746	regulation of lipoprotein metabolic process	4.859468e-8
GO:0001957	intramembranous ossification	7.175316e-8
GO:0010718	positive regulation of epithelial to mesenchymal transition	7.448505e-8
GO:0060350	endochondral bone morphogenesis	7.840327e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	8.528357e-8
GO:0006260	DNA replication	1.521333e-7
GO:0000303	response to superoxide	1.998474e-7
GO:0006011	UDP-glucose metabolic process	2.159048e-7
GO:0034442	regulation of lipoprotein oxidation	2.498578e-7
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	3.109750e-7
GO:0046470	phosphatidylcholine metabolic process	3.856423e-7
GO:0001958	endochondral ossification	4.367930e-7
GO:0071267	L-methionine salvage	4.481747e-7
GO:0060349	bone morphogenesis	6.604379e-7
GO:0042572	retinol metabolic process	8.356093e-7
GO:0008612	peptidyl-lysine modification to hypusine	1.000229e-6
GO:0021903	rostrocaudal neural tube patterning	1.202935e-6
GO:0010896	regulation of triglyceride catabolic process	1.270884e-6
GO:0006259	DNA metabolic process	1.459791e-6
GO:0034369	plasma lipoprotein particle remodeling	1.586010e-6
GO:0031947	negative regulation of glucocorticoid biosynthetic process	1.744441e-6
GO:0021993	initiation of neural tube closure	1.744441e-6
GO:0043691	reverse cholesterol transport	2.038918e-6
GO:0006801	superoxide metabolic process	2.069766e-6
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	3.125718e-6
GO:0051586	positive regulation of dopamine uptake	3.144632e-6
GO:0060343	trabecula formation	3.221113e-6
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.234332e-6
GO:0071218	cellular response to misfolded protein	3.284524e-6
GO:0006515	misfolded or incompletely synthesized protein catabolic process	3.533572e-6
GO:0015876	acetyl-CoA transport	3.829801e-6
GO:0031536	positive regulation of exit from mitosis	4.185049e-6
GO:0019509	L-methionine salvage from methylthioadenosine	4.196719e-6
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	5.484766e-6
GO:0021532	neural tube patterning	5.581259e-6
GO:0016557	peroxisome membrane biogenesis	5.669171e-6
GO:0016574	histone ubiquitination	6.278847e-6
GO:0045723	positive regulation of fatty acid biosynthetic process	7.246581e-6
GO:0070602	regulation of centromeric sister chromatid cohesion	7.852635e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	8.258374e-6
GO:0042733	embryonic digit morphogenesis	8.584106e-6
GO:0061383	trabecula morphogenesis	9.389008e-6
GO:0010454	negative regulation of cell fate commitment	9.522180e-6
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.008568e-5
GO:0006270	DNA-dependent DNA replication initiation	1.008568e-5
GO:0001830	trophectodermal cell fate commitment	1.012627e-5
GO:0071103	DNA conformation change	1.179888e-5
GO:0061181	regulation of chondrocyte development	1.254568e-5
GO:0016559	peroxisome fission	1.277347e-5
GO:0050748	negative regulation of lipoprotein metabolic process	1.634510e-5
GO:0034633	retinol transport	1.638142e-5
GO:0021528	commissural neuron differentiation in spinal cord	1.874036e-5
GO:0002561	basophil degranulation	1.874036e-5
GO:0042304	regulation of fatty acid biosynthetic process	1.946047e-5
GO:0007130	synaptonemal complex assembly	1.953683e-5
GO:0017196	N-terminal peptidyl-methionine acetylation	2.094716e-5
GO:0055090	acylglycerol homeostasis	2.514586e-5
GO:0048483	autonomic nervous system development	2.541608e-5
GO:0060828	regulation of canonical Wnt receptor signaling pathway	2.716605e-5
GO:0021555	midbrain-hindbrain boundary morphogenesis	2.732157e-5
GO:0006807	nitrogen compound metabolic process	2.748063e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	2.878542e-5
GO:0048368	lateral mesoderm development	2.996545e-5
GO:0060644	mammary gland epithelial cell differentiation	3.153086e-5
GO:0034641	cellular nitrogen compound metabolic process	3.236827e-5
GO:0060346	bone trabecula formation	3.358712e-5
GO:0031396	regulation of protein ubiquitination	3.557759e-5
GO:0006303	double-strand break repair via nonhomologous end joining	3.590241e-5
GO:0000413	protein peptidyl-prolyl isomerization	3.688301e-5
GO:0006297	nucleotide-excision repair, DNA gap filling	3.762098e-5
GO:0010717	regulation of epithelial to mesenchymal transition	3.965911e-5
GO:0000492	box C/D snoRNP assembly	4.058940e-5
GO:0032423	regulation of mismatch repair	4.202904e-5
GO:0090304	nucleic acid metabolic process	4.288108e-5
GO:0006417	regulation of translation	4.297264e-5
GO:0006434	seryl-tRNA aminoacylation	4.488342e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	4.899030e-5
GO:0051182	coenzyme transport	5.224035e-5
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	5.224035e-5
GO:0010897	negative regulation of triglyceride catabolic process	5.224035e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.224035e-5
GO:0072337	modified amino acid transport	5.294406e-5
GO:0003350	pulmonary myocardium development	6.308336e-5
GO:0002507	tolerance induction	6.575798e-5
GO:0071843	cellular component biogenesis at cellular level	6.695699e-5
GO:0070193	synaptonemal complex organization	6.934331e-5
GO:0006457	protein folding	6.946599e-5
GO:0060012	synaptic transmission, glycinergic	7.368159e-5
GO:0006982	response to lipid hydroperoxide	7.553874e-5
GO:0031943	regulation of glucocorticoid metabolic process	7.761157e-5
GO:0042254	ribosome biogenesis	7.980224e-5
GO:0070327	thyroid hormone transport	8.261879e-5
GO:0006412	translation	8.337812e-5
GO:0046502	uroporphyrinogen III metabolic process	8.410815e-5
GO:0000279	M phase	8.903611e-5
GO:0006414	translational elongation	9.223931e-5
GO:0060621	negative regulation of cholesterol import	9.780609e-5
GO:0018208	peptidyl-proline modification	9.847382e-5
GO:0034375	high-density lipoprotein particle remodeling	9.915505e-5
GO:0009950	dorsal/ventral axis specification	9.984889e-5
GO:0030917	midbrain-hindbrain boundary development	1.015875e-4
GO:0002335	mature B cell differentiation	1.015875e-4
GO:0034587	piRNA metabolic process	1.086118e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	1.086118e-4
GO:0010608	posttranscriptional regulation of gene expression	1.109197e-4
GO:0045575	basophil activation	1.128597e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	1.128597e-4
GO:0009236	cobalamin biosynthetic process	1.128597e-4
GO:0006409	tRNA export from nucleus	1.128597e-4
GO:0021572	rhombomere 6 development	1.149996e-4
GO:0040029	regulation of gene expression, epigenetic	1.163262e-4
GO:0044240	multicellular organismal lipid catabolic process	1.216185e-4
GO:0010720	positive regulation of cell development	1.253478e-4
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.263871e-4
GO:0070079	histone H4-R3 demethylation	1.320191e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.320191e-4
GO:0070078	histone H3-R2 demethylation	1.320191e-4
GO:0007128	meiotic prophase I	1.409901e-4
GO:0030300	regulation of intestinal cholesterol absorption	1.464633e-4
GO:0042744	hydrogen peroxide catabolic process	1.552421e-4
GO:0051788	response to misfolded protein	1.556201e-4
GO:0045585	positive regulation of cytotoxic T cell differentiation	1.574380e-4
GO:0045581	negative regulation of T cell differentiation	1.618718e-4
GO:0031397	negative regulation of protein ubiquitination	1.743318e-4
GO:0006415	translational termination	1.761422e-4
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.825886e-4
GO:0071044	histone mRNA catabolic process	1.846519e-4
GO:0016458	gene silencing	1.848623e-4
GO:0006642	triglyceride mobilization	1.854465e-4
GO:0022613	ribonucleoprotein complex biogenesis	1.912817e-4
GO:0060897	neural plate regionalization	1.927475e-4
GO:0031047	gene silencing by RNA	1.996118e-4
GO:0035518	histone H2A monoubiquitination	2.085524e-4
GO:0042439	ethanolamine-containing compound metabolic process	2.188316e-4
GO:0001706	endoderm formation	2.218648e-4
GO:0045347	negative regulation of MHC class II biosynthetic process	2.226466e-4
GO:0034505	tooth mineralization	2.259959e-4
GO:0072124	regulation of glomerular mesangial cell proliferation	2.267898e-4
GO:0070368	positive regulation of hepatocyte differentiation	2.313030e-4
GO:0002320	lymphoid progenitor cell differentiation	2.366831e-4
GO:0070192	chromosome organization involved in meiosis	2.384077e-4
GO:0006323	DNA packaging	2.396827e-4
GO:0046503	glycerolipid catabolic process	2.451878e-4
GO:0048484	enteric nervous system development	2.714902e-4
GO:0032057	negative regulation of translational initiation in response to stress	2.939717e-4
GO:0072110	glomerular mesangial cell proliferation	2.963654e-4
GO:0048706	embryonic skeletal system development	3.034267e-4
GO:0001947	heart looping	3.138460e-4
GO:0033522	histone H2A ubiquitination	3.207167e-4
GO:0019433	triglyceride catabolic process	3.306715e-4
GO:0060620	regulation of cholesterol import	3.346558e-4
GO:0006656	phosphatidylcholine biosynthetic process	3.381535e-4
GO:0051639	actin filament network formation	3.522723e-4
GO:0045727	positive regulation of translation	3.604506e-4
GO:0045620	negative regulation of lymphocyte differentiation	3.717143e-4
GO:0050928	negative regulation of positive chemotaxis	3.885974e-4
GO:0001579	medium-chain fatty acid transport	3.885974e-4
GO:0006258	UDP-glucose catabolic process	3.885974e-4
GO:0060841	venous blood vessel development	4.109360e-4
GO:0051580	regulation of neurotransmitter uptake	4.191002e-4
GO:0006809	nitric oxide biosynthetic process	4.191002e-4
GO:0002679	respiratory burst involved in defense response	4.191002e-4
GO:0006446	regulation of translational initiation	4.332520e-4
GO:0006139	nucleobase-containing compound metabolic process	4.409720e-4
GO:0021678	third ventricle development	4.411467e-4
GO:0070307	lens fiber cell development	4.433366e-4
GO:0032353	negative regulation of hormone biosynthetic process	4.467872e-4
GO:0071827	plasma lipoprotein particle organization	4.628858e-4
GO:0009996	negative regulation of cell fate specification	4.742342e-4
GO:0010812	negative regulation of cell-substrate adhesion	4.811706e-4
GO:0033084	regulation of immature T cell proliferation in thymus	5.008155e-4
GO:0006695	cholesterol biosynthetic process	5.152695e-4
GO:0008535	respiratory chain complex IV assembly	5.257334e-4
GO:0051176	positive regulation of sulfur metabolic process	5.403492e-4
GO:0035621	ER to Golgi ceramide transport	5.461282e-4
GO:0000237	leptotene	5.461282e-4
GO:0002227	innate immune response in mucosa	5.479873e-4
GO:2000758	positive regulation of peptidyl-lysine acetylation	5.758099e-4
GO:0060282	positive regulation of oocyte development	5.816624e-4
GO:0060281	regulation of oocyte development	5.816624e-4
GO:0034446	substrate adhesion-dependent cell spreading	5.859902e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	5.876918e-4
GO:0016078	tRNA catabolic process	5.962957e-4
GO:0001682	tRNA 5'-leader removal	5.962957e-4
GO:0090136	epithelial cell-cell adhesion	6.033194e-4
GO:0006482	protein demethylation	6.168222e-4
GO:0046464	acylglycerol catabolic process	6.304126e-4
GO:0032119	sequestering of zinc ion	6.325591e-4
GO:0010665	regulation of cardiac muscle cell apoptosis	6.633323e-4
GO:0051351	positive regulation of ligase activity	7.258176e-4
GO:0016090	prenol metabolic process	7.267189e-4
GO:0006448	regulation of translational elongation	7.510205e-4
GO:0043584	nose development	7.564816e-4
GO:0034645	cellular macromolecule biosynthetic process	7.629715e-4
GO:0021592	fourth ventricle development	7.676566e-4
GO:0030953	astral microtubule organization	7.740202e-4
GO:0090207	regulation of triglyceride metabolic process	7.843162e-4
GO:0071506	cellular response to mycophenolic acid	8.060180e-4
GO:0072126	positive regulation of glomerular mesangial cell proliferation	8.060180e-4
GO:0071712	ER-associated misfolded protein catabolic process	8.109029e-4
GO:0070328	triglyceride homeostasis	9.378338e-4
GO:0007126	meiosis	9.392722e-4
GO:0017148	negative regulation of translation	9.443292e-4
GO:0006669	sphinganine-1-phosphate biosynthetic process	9.568447e-4
GO:0003401	axis elongation	9.608685e-4
GO:0010390	histone monoubiquitination	9.675865e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.004076e-3
GO:0071247	cellular response to chromate	1.004076e-3
GO:0046108	uridine metabolic process	1.004076e-3
GO:0010986	positive regulation of lipoprotein particle clearance	1.004076e-3
GO:0055118	negative regulation of cardiac muscle contraction	1.018147e-3
GO:0007129	synapsis	1.019178e-3
GO:0006334	nucleosome assembly	1.020838e-3
GO:0065005	protein-lipid complex assembly	1.064097e-3
GO:0006577	betaine metabolic process	1.079366e-3
GO:0045963	negative regulation of dopamine metabolic process	1.079410e-3
GO:0050668	positive regulation of homocysteine metabolic process	1.079410e-3
GO:0034421	post-translational protein acetylation	1.079410e-3
GO:0006428	isoleucyl-tRNA aminoacylation	1.079410e-3
GO:0045947	negative regulation of translational initiation	1.085297e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.125881e-3
GO:0051216	cartilage development	1.127636e-3
GO:0007063	regulation of sister chromatid cohesion	1.132261e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	1.133497e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.172296e-3
GO:0033083	regulation of immature T cell proliferation	1.189047e-3
GO:0043550	regulation of lipid kinase activity	1.193156e-3
GO:0030111	regulation of Wnt receptor signaling pathway	1.199194e-3
GO:0008354	germ cell migration	1.209226e-3
GO:0044319	wound healing, spreading of cells	1.227289e-3
GO:0007096	regulation of exit from mitosis	1.228283e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	1.271069e-3
GO:0010656	negative regulation of muscle cell apoptosis	1.296720e-3
GO:0009799	specification of symmetry	1.309683e-3
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	1.324678e-3
GO:0000726	non-recombinational repair	1.340616e-3
GO:0002328	pro-B cell differentiation	1.349965e-3
GO:0002268	follicular dendritic cell differentiation	1.357173e-3
GO:0060914	heart formation	1.397232e-3
GO:0014002	astrocyte development	1.477420e-3
GO:0060896	neural plate pattern specification	1.487564e-3
GO:0009059	macromolecule biosynthetic process	1.501312e-3
GO:0045905	positive regulation of translational termination	1.506557e-3
GO:0006452	translational frameshifting	1.506557e-3
GO:0045901	positive regulation of translational elongation	1.506557e-3
GO:0045454	cell redox homeostasis	1.512653e-3
GO:0016199	axon midline choice point recognition	1.541763e-3
GO:0010898	positive regulation of triglyceride catabolic process	1.599974e-3
GO:0030046	parallel actin filament bundle assembly	1.666260e-3
GO:0035524	proline transmembrane transport	1.705678e-3
GO:0035634	response to stilbenoid	1.746975e-3
GO:0035967	cellular response to topologically incorrect protein	1.754316e-3
GO:0002098	tRNA wobble uridine modification	1.759536e-3
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1.759536e-3
GO:0035313	wound healing, spreading of epidermal cells	1.762531e-3
GO:0021513	spinal cord dorsal/ventral patterning	1.793686e-3
GO:0002149	hypochlorous acid biosynthetic process	1.796295e-3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	1.797565e-3
GO:0044091	membrane biogenesis	1.798866e-3
GO:0034241	positive regulation of macrophage fusion	1.804886e-3
GO:0010189	vitamin E biosynthetic process	1.804886e-3
GO:0046434	organophosphate catabolic process	1.812721e-3
GO:0021511	spinal cord patterning	1.838518e-3
GO:0010312	detoxification of zinc ion	1.851149e-3
GO:0034614	cellular response to reactive oxygen species	1.887334e-3
GO:0006438	valyl-tRNA aminoacylation	1.921313e-3
GO:0045653	negative regulation of megakaryocyte differentiation	1.942190e-3
GO:0009309	amine biosynthetic process	2.033563e-3
GO:0048521	negative regulation of behavior	2.050377e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	2.096442e-3
GO:0003127	detection of nodal flow	2.096442e-3
GO:0018126	protein hydroxylation	2.170825e-3
GO:0019987	negative regulation of anti-apoptosis	2.174689e-3
GO:0003002	regionalization	2.181833e-3
GO:0044085	cellular component biogenesis	2.224927e-3
GO:0006268	DNA unwinding involved in replication	2.244818e-3
GO:0044106	cellular amine metabolic process	2.284048e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.379908e-3
GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	2.385827e-3
GO:0055119	relaxation of cardiac muscle	2.389896e-3
GO:0051321	meiotic cell cycle	2.408463e-3
GO:0002536	respiratory burst involved in inflammatory response	2.422283e-3
GO:0051066	dihydrobiopterin metabolic process	2.422283e-3
GO:0061180	mammary gland epithelium development	2.534582e-3
GO:0060348	bone development	2.562208e-3
GO:0016070	RNA metabolic process	2.597038e-3
GO:0007492	endoderm development	2.603479e-3
GO:0021563	glossopharyngeal nerve development	2.813637e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.816422e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.816422e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	2.854245e-3
GO:0071361	cellular response to ethanol	2.977530e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	2.999565e-3
GO:0018343	protein farnesylation	2.999565e-3
GO:0060286	flagellar cell motility	2.999565e-3
GO:0021999	neural plate anterior/posterior regionalization	3.032002e-3
GO:0060968	regulation of gene silencing	3.038251e-3
GO:0055070	copper ion homeostasis	3.067527e-3
GO:0030150	protein import into mitochondrial matrix	3.068301e-3
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	3.068301e-3
GO:0046670	positive regulation of retinal cell programmed cell death	3.068301e-3
GO:0018872	arsonoacetate metabolic process	3.068301e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	3.068301e-3
GO:0021670	lateral ventricle development	3.074141e-3
GO:0097006	regulation of plasma lipoprotein particle levels	3.080956e-3
GO:0015879	carnitine transport	3.131995e-3
GO:0045338	farnesyl diphosphate metabolic process	3.166181e-3
GO:0007030	Golgi organization	3.176808e-3
GO:0021544	subpallium development	3.178535e-3
GO:0046323	glucose import	3.183595e-3
GO:0060013	righting reflex	3.207669e-3
GO:0042398	cellular modified amino acid biosynthetic process	3.282131e-3
GO:2000756	regulation of peptidyl-lysine acetylation	3.307660e-3
GO:0090192	regulation of glomerulus development	3.361884e-3
GO:0042476	odontogenesis	3.372230e-3
GO:0002385	mucosal immune response	3.418117e-3
GO:0016577	histone demethylation	3.483332e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	3.605192e-3
GO:0042938	dipeptide transport	3.605192e-3
GO:0045628	regulation of T-helper 2 cell differentiation	3.679372e-3
GO:0002313	mature B cell differentiation involved in immune response	3.685604e-3
GO:0022403	cell cycle phase	3.737172e-3
GO:0060579	ventral spinal cord interneuron fate commitment	3.809001e-3
GO:0010467	gene expression	3.817719e-3
GO:0007368	determination of left/right symmetry	3.877589e-3
GO:0006278	RNA-dependent DNA replication	3.878114e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	3.904008e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	4.015233e-3
GO:0016236	macroautophagy	4.023135e-3
GO:0070988	demethylation	4.038993e-3
GO:0048705	skeletal system morphogenesis	4.040367e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	4.052273e-3
GO:0051340	regulation of ligase activity	4.068777e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	4.103766e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	4.113830e-3
GO:0021756	striatum development	4.163407e-3
GO:0070846	Hsp90 deacetylation	4.165366e-3
GO:0090042	tubulin deacetylation	4.165366e-3
GO:0006780	uroporphyrinogen III biosynthetic process	4.165366e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	4.165366e-3
GO:0002462	tolerance induction to nonself antigen	4.165366e-3
GO:0048496	maintenance of organ identity	4.185271e-3
GO:0035993	deltoid tuberosity development	4.185271e-3
GO:0061154	endothelial tube morphogenesis	4.203827e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	4.203827e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	4.203827e-3
GO:0034227	tRNA thio-modification	4.203827e-3
GO:0006449	regulation of translational termination	4.203827e-3
GO:0072593	reactive oxygen species metabolic process	4.208215e-3
GO:0051006	positive regulation of lipoprotein lipase activity	4.245807e-3
GO:0032329	serine transport	4.246622e-3
GO:0006474	N-terminal protein amino acid acetylation	4.267847e-3
GO:0031122	cytoplasmic microtubule organization	4.305720e-3
GO:0035108	limb morphogenesis	4.312905e-3
GO:0070407	oxidation-dependent protein catabolic process	4.329876e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	4.329876e-3
GO:0042823	pyridoxal phosphate biosynthetic process	4.633741e-3
GO:0010994	free ubiquitin chain polymerization	4.633741e-3
GO:0006413	translational initiation	4.676660e-3
GO:0060973	cell migration involved in heart development	4.793573e-3
GO:0000302	response to reactive oxygen species	4.808219e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	4.836190e-3
GO:0006657	CDP-choline pathway	4.836190e-3
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	4.836190e-3
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	4.884870e-3
GO:0090218	positive regulation of lipid kinase activity	4.918377e-3
GO:0051647	nucleus localization	5.014381e-3
GO:0032967	positive regulation of collagen biosynthetic process	5.015615e-3
GO:0031497	chromatin assembly	5.017346e-3
GO:0032024	positive regulation of insulin secretion	5.176945e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.254424e-3
GO:0006668	sphinganine-1-phosphate metabolic process	5.264951e-3
GO:0042743	hydrogen peroxide metabolic process	5.275508e-3
GO:0003215	cardiac right ventricle morphogenesis	5.275508e-3
GO:0016126	sterol biosynthetic process	5.275508e-3
GO:0090208	positive regulation of triglyceride metabolic process	5.425394e-3
GO:0031394	positive regulation of prostaglandin biosynthetic process	5.426201e-3
GO:0051238	sequestering of metal ion	5.426201e-3
GO:0030261	chromosome condensation	5.455658e-3
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	5.603214e-3
GO:0072498	embryonic skeletal joint development	5.656703e-3
GO:0006261	DNA-dependent DNA replication	5.667101e-3
GO:0097070	ductus arteriosus closure	5.685845e-3
GO:0065004	protein-DNA complex assembly	5.723092e-3
GO:0009107	lipoate biosynthetic process	5.815251e-3
GO:0070845	polyubiquitinated misfolded protein transport	5.815251e-3
GO:0002251	organ or tissue specific immune response	5.839440e-3
GO:0006999	nuclear pore organization	5.874404e-3
GO:0044260	cellular macromolecule metabolic process	5.876711e-3
GO:0008334	histone mRNA metabolic process	5.883699e-3
GO:0006304	DNA modification	5.894365e-3
GO:0034728	nucleosome organization	5.900517e-3
GO:0070544	histone H3-K36 demethylation	6.001546e-3
GO:0006720	isoprenoid metabolic process	6.106023e-3
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	6.106741e-3
GO:0000239	pachytene	6.121486e-3
GO:0035089	establishment of apical/basal cell polarity	6.440231e-3
GO:0002315	marginal zone B cell differentiation	6.440231e-3
GO:0070306	lens fiber cell differentiation	6.741039e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	6.790243e-3
GO:0021521	ventral spinal cord interneuron specification	6.825778e-3
GO:0035990	tendon cell differentiation	6.872094e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	6.872094e-3
GO:0006346	methylation-dependent chromatin silencing	6.992105e-3
GO:0018193	peptidyl-amino acid modification	7.019055e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	7.081652e-3
GO:0006713	glucocorticoid catabolic process	7.081652e-3
GO:0003241	growth involved in heart morphogenesis	7.081652e-3
GO:0006306	DNA methylation	7.120592e-3
GO:0070979	protein K11-linked ubiquitination	7.210209e-3
GO:0070301	cellular response to hydrogen peroxide	7.214230e-3
GO:0032717	negative regulation of interleukin-8 production	7.281851e-3
GO:0060272	embryonic skeletal joint morphogenesis	7.317683e-3
GO:0045661	regulation of myoblast differentiation	7.319156e-3
GO:0034139	regulation of toll-like receptor 3 signaling pathway	7.406464e-3
GO:0035066	positive regulation of histone acetylation	7.414124e-3
GO:0003130	BMP signaling pathway involved in heart induction	7.414432e-3
GO:0032055	negative regulation of translation in response to stress	7.517546e-3
GO:0042364	water-soluble vitamin biosynthetic process	7.579385e-3
GO:0019276	UDP-N-acetylgalactosamine metabolic process	7.590409e-3
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	7.590409e-3
GO:0015825	L-serine transport	7.590409e-3
GO:0007412	axon target recognition	7.590409e-3
GO:0001755	neural crest cell migration	7.605754e-3
GO:0060592	mammary gland formation	7.675155e-3
GO:0032691	negative regulation of interleukin-1 beta production	7.680250e-3
GO:0050996	positive regulation of lipid catabolic process	7.968238e-3
GO:0051148	negative regulation of muscle cell differentiation	7.970362e-3
GO:0060670	branching involved in embryonic placenta morphogenesis	8.001691e-3
GO:0032474	otolith morphogenesis	8.012312e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	8.012312e-3
GO:0065002	intracellular protein transmembrane transport	8.012312e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	8.012312e-3
GO:0003210	cardiac atrium formation	8.012312e-3
GO:0003236	sinus venosus morphogenesis	8.012312e-3
GO:0003259	cardioblast anterior-lateral migration	8.012312e-3
GO:0006662	glycerol ether metabolic process	8.045986e-3
GO:0090239	regulation of histone H4 acetylation	8.116979e-3
GO:0060174	limb bud formation	8.170186e-3
GO:0002052	positive regulation of neuroblast proliferation	8.277098e-3
GO:0006878	cellular copper ion homeostasis	8.294113e-3
GO:0034660	ncRNA metabolic process	8.302104e-3
GO:0001825	blastocyst formation	8.365300e-3
GO:0051181	cofactor transport	8.398767e-3
GO:0032314	regulation of Rac GTPase activity	8.478817e-3
GO:0006089	lactate metabolic process	8.494308e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	8.528815e-3
GO:0060391	positive regulation of SMAD protein import into nucleus	8.729075e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	8.779935e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	8.898441e-3
GO:0006273	lagging strand elongation	8.898441e-3
GO:0060480	lung goblet cell differentiation	8.898441e-3
GO:0044241	lipid digestion	9.002840e-3
GO:0006654	phosphatidic acid biosynthetic process	9.282110e-3
GO:0010613	positive regulation of cardiac muscle hypertrophy	9.488596e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	9.551559e-3
GO:0034621	cellular macromolecular complex subunit organization	9.564968e-3
GO:0060068	vagina development	9.590974e-3
GO:0006418	tRNA aminoacylation for protein translation	9.657967e-3
GO:0051645	Golgi localization	9.676915e-3
GO:0072109	glomerular mesangium development	9.676915e-3
GO:0060433	bronchus development	9.760559e-3
GO:0018342	protein prenylation	9.796833e-3
GO:0021508	floor plate formation	9.838635e-3
GO:0033091	positive regulation of immature T cell proliferation	1.013766e-2
GO:0043932	ossification involved in bone remodeling	1.017324e-2
GO:0006561	proline biosynthetic process	1.017324e-2
GO:0033505	floor plate morphogenesis	1.017324e-2
GO:0006081	cellular aldehyde metabolic process	1.021633e-2
GO:0051303	establishment of chromosome localization	1.022322e-2
GO:0003211	cardiac ventricle formation	1.031138e-2
GO:0045767	regulation of anti-apoptosis	1.042498e-2
GO:0032692	negative regulation of interleukin-1 production	1.046384e-2
GO:0003139	secondary heart field specification	1.052414e-2
GO:0060840	artery development	1.053179e-2
GO:0032508	DNA duplex unwinding	1.056836e-2
GO:0021773	striatal medium spiny neuron differentiation	1.056836e-2
GO:0018202	peptidyl-histidine modification	1.056836e-2
GO:0009437	carnitine metabolic process	1.056836e-2
GO:0008652	cellular amino acid biosynthetic process	1.062729e-2
GO:0050930	induction of positive chemotaxis	1.071415e-2
GO:0001569	patterning of blood vessels	1.075418e-2
GO:0001714	endodermal cell fate specification	1.091741e-2
GO:0001842	neural fold formation	1.091741e-2
GO:0048844	artery morphogenesis	1.105782e-2
GO:0032222	regulation of synaptic transmission, cholinergic	1.120823e-2
GO:0045669	positive regulation of osteoblast differentiation	1.121263e-2
GO:0006520	cellular amino acid metabolic process	1.124841e-2
GO:0002897	positive regulation of central B cell tolerance induction	1.135469e-2
GO:0072553	terminal button organization	1.135469e-2
GO:0002508	central tolerance induction	1.135469e-2
GO:0002125	maternal aggressive behavior	1.135469e-2
GO:0021591	ventricular system development	1.144815e-2
GO:0072527	pyrimidine-containing compound metabolic process	1.145176e-2
GO:0043056	forward locomotion	1.156841e-2
GO:0001935	endothelial cell proliferation	1.168048e-2
GO:0033574	response to testosterone stimulus	1.174238e-2