Novel motif:87

name:	motif87_RCGCACWS

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0038007	netrin-activated signaling pathway	1.600587e-8
GO:0002074	extraocular skeletal muscle development	1.714743e-8
GO:0021903	rostrocaudal neural tube patterning	8.216173e-8
GO:0050746	regulation of lipoprotein metabolic process	8.860561e-8
GO:0019101	female somatic sex determination	1.089841e-7
GO:0042703	menstruation	1.089841e-7
GO:0021535	cell migration in hindbrain	1.540812e-7
GO:0021536	diencephalon development	2.169174e-7
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.486469e-7
GO:0014028	notochord formation	2.771629e-7
GO:2000097	regulation of smooth muscle cell-matrix adhesion	3.239800e-7
GO:0008635	activation of caspase activity by cytochrome c	4.844188e-7
GO:0070192	chromosome organization involved in meiosis	5.254200e-7
GO:0043301	negative regulation of leukocyte degranulation	6.274260e-7
GO:0035094	response to nicotine	7.542050e-7
GO:0010765	positive regulation of sodium ion transport	9.449853e-7
GO:0033057	multicellular organismal reproductive behavior	1.015634e-6
GO:0043305	negative regulation of mast cell degranulation	1.809796e-6
GO:0014806	smooth muscle hyperplasia	2.282681e-6
GO:0007288	sperm axoneme assembly	2.670066e-6
GO:0050703	interleukin-1 alpha secretion	2.855928e-6
GO:0000089	mitotic metaphase	3.229700e-6
GO:0009650	UV protection	3.668877e-6
GO:0071258	cellular response to gravity	3.848089e-6
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	3.848089e-6
GO:0061044	negative regulation of vascular wound healing	3.848089e-6
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	3.848089e-6
GO:0007128	meiotic prophase I	3.918824e-6
GO:0033590	response to cobalamin	4.268985e-6
GO:0006117	acetaldehyde metabolic process	4.268985e-6
GO:0071460	cellular response to cell-matrix adhesion	4.290701e-6
GO:0007286	spermatid development	6.865742e-6
GO:0006473	protein acetylation	8.437376e-6
GO:0090102	cochlea development	8.699624e-6
GO:0050747	positive regulation of lipoprotein metabolic process	8.733199e-6
GO:0006475	internal protein amino acid acetylation	9.745147e-6
GO:0006383	transcription from RNA polymerase III promoter	9.928031e-6
GO:0003105	negative regulation of glomerular filtration	1.091634e-5
GO:0097045	phosphatidylserine exposure on blood platelet	1.115192e-5
GO:0006386	termination of RNA polymerase III transcription	1.137034e-5
GO:0006385	transcription elongation from RNA polymerase III promoter	1.137034e-5
GO:0055075	potassium ion homeostasis	1.186021e-5
GO:0070474	positive regulation of uterine smooth muscle contraction	1.251743e-5
GO:0048515	spermatid differentiation	1.308495e-5
GO:0022601	menstrual cycle phase	1.344543e-5
GO:0018205	peptidyl-lysine modification	1.377994e-5
GO:0010224	response to UV-B	1.560490e-5
GO:0021675	nerve development	1.765357e-5
GO:0007638	mechanosensory behavior	1.873261e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.021706e-5
GO:0060033	anatomical structure regression	2.046639e-5
GO:0021603	cranial nerve formation	2.470948e-5
GO:0033683	nucleotide-excision repair, DNA incision	2.470948e-5
GO:0007129	synapsis	2.481418e-5
GO:0021877	forebrain neuron fate commitment	2.718575e-5
GO:0000413	protein peptidyl-prolyl isomerization	2.967479e-5
GO:0045760	positive regulation of action potential	2.968095e-5
GO:0021932	hindbrain radial glia guided cell migration	3.143746e-5
GO:0021879	forebrain neuron differentiation	3.292618e-5
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	3.429231e-5
GO:0009296	flagellum assembly	3.659001e-5
GO:0043491	protein kinase B signaling cascade	3.677974e-5
GO:0021559	trigeminal nerve development	3.728672e-5
GO:0014040	positive regulation of Schwann cell differentiation	3.904165e-5
GO:0043543	protein acylation	3.958221e-5
GO:0060850	regulation of transcription involved in cell fate commitment	4.070992e-5
GO:0002200	somatic diversification of immune receptors	4.198139e-5
GO:0010721	negative regulation of cell development	4.373903e-5
GO:0007130	synaptonemal complex assembly	4.747131e-5
GO:0046108	uridine metabolic process	5.224923e-5
GO:0018394	peptidyl-lysine acetylation	5.267081e-5
GO:0006308	DNA catabolic process	5.295723e-5
GO:0033233	regulation of protein sumoylation	5.418573e-5
GO:0007616	long-term memory	5.725978e-5
GO:0060591	chondroblast differentiation	5.733985e-5
GO:0009263	deoxyribonucleotide biosynthetic process	5.779498e-5
GO:0060035	notochord cell development	5.849022e-5
GO:0018393	internal peptidyl-lysine acetylation	5.882567e-5
GO:0045116	protein neddylation	5.939809e-5
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	6.516652e-5
GO:0033235	positive regulation of protein sumoylation	6.523697e-5
GO:0042369	vitamin D catabolic process	6.975665e-5
GO:0051323	metaphase	7.161307e-5
GO:2000124	regulation of endocannabinoid signaling pathway	7.197392e-5
GO:0051324	prophase	7.215705e-5
GO:0060014	granulosa cell differentiation	7.275751e-5
GO:0021983	pituitary gland development	7.660335e-5
GO:0021545	cranial nerve development	7.780358e-5
GO:0006108	malate metabolic process	7.788523e-5
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	7.849926e-5
GO:0021892	cerebral cortex GABAergic interneuron differentiation	8.331473e-5
GO:0031223	auditory behavior	8.929221e-5
GO:0060596	mammary placode formation	9.458959e-5
GO:0019087	transformation of host cell by virus	1.033583e-4
GO:0042069	regulation of catecholamine metabolic process	1.067024e-4
GO:0006821	chloride transport	1.070438e-4
GO:0072148	epithelial cell fate commitment	1.094808e-4
GO:0045792	negative regulation of cell size	1.169424e-4
GO:0045471	response to ethanol	1.169835e-4
GO:2000465	regulation of glycogen (starch) synthase activity	1.170853e-4
GO:0051260	protein homooligomerization	1.289006e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	1.326817e-4
GO:0033151	V(D)J recombination	1.375170e-4
GO:0034442	regulation of lipoprotein oxidation	1.378737e-4
GO:0031017	exocrine pancreas development	1.383058e-4
GO:0008654	phospholipid biosynthetic process	1.432280e-4
GO:0007020	microtubule nucleation	1.449871e-4
GO:0014707	branchiomeric skeletal muscle development	1.525622e-4
GO:0021707	cerebellar granule cell differentiation	1.530815e-4
GO:0030852	regulation of granulocyte differentiation	1.556240e-4
GO:0060026	convergent extension	1.644819e-4
GO:0072592	oxygen metabolic process	1.665250e-4
GO:0021794	thalamus development	1.698279e-4
GO:0001661	conditioned taste aversion	1.702355e-4
GO:0021872	forebrain generation of neurons	1.742946e-4
GO:0045212	neurotransmitter receptor biosynthetic process	1.767602e-4
GO:0072355	histone H3-T3 phosphorylation	1.767602e-4
GO:0032223	negative regulation of synaptic transmission, cholinergic	1.767602e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	1.767602e-4
GO:0007420	brain development	1.783472e-4
GO:0014037	Schwann cell differentiation	1.816135e-4
GO:0032411	positive regulation of transporter activity	1.863450e-4
GO:0006283	transcription-coupled nucleotide-excision repair	1.907748e-4
GO:0035261	external genitalia morphogenesis	2.001161e-4
GO:0032741	positive regulation of interleukin-18 production	2.016428e-4
GO:0009956	radial pattern formation	2.016428e-4
GO:0032464	positive regulation of protein homooligomerization	2.080032e-4
GO:0018208	peptidyl-proline modification	2.219834e-4
GO:0050768	negative regulation of neurogenesis	2.374818e-4
GO:0006788	heme oxidation	2.409851e-4
GO:0002886	regulation of myeloid leukocyte mediated immunity	2.415707e-4
GO:0016573	histone acetylation	2.481035e-4
GO:0048562	embryonic organ morphogenesis	2.537679e-4
GO:0021943	formation of radial glial scaffolds	2.582428e-4
GO:0031104	dendrite regeneration	2.668620e-4
GO:0010939	regulation of necrotic cell death	2.774449e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.787602e-4
GO:0003406	retinal pigment epithelium development	2.905460e-4
GO:0048842	positive regulation of axon extension involved in axon guidance	2.948121e-4
GO:0030574	collagen catabolic process	2.978369e-4
GO:0042552	myelination	3.044299e-4
GO:0045007	depurination	3.090811e-4
GO:0022011	myelination in peripheral nervous system	3.228761e-4
GO:0014014	negative regulation of gliogenesis	3.399148e-4
GO:0009265	2'-deoxyribonucleotide biosynthetic process	3.459905e-4
GO:0030262	apoptotic nuclear change	3.509831e-4
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	3.677841e-4
GO:0030917	midbrain-hindbrain boundary development	3.803750e-4
GO:0032007	negative regulation of TOR signaling cascade	3.807074e-4
GO:0021557	oculomotor nerve development	3.887627e-4
GO:0040018	positive regulation of multicellular organism growth	3.953987e-4
GO:0014044	Schwann cell development	4.005030e-4
GO:0050905	neuromuscular process	4.052115e-4
GO:0014038	regulation of Schwann cell differentiation	4.212240e-4
GO:0040040	thermosensory behavior	4.250474e-4
GO:0002069	columnar/cuboidal epithelial cell maturation	4.411721e-4
GO:0034470	ncRNA processing	4.431200e-4
GO:0001830	trophectodermal cell fate commitment	4.448302e-4
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	4.448302e-4
GO:0030902	hindbrain development	4.457704e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	4.491230e-4
GO:0042053	regulation of dopamine metabolic process	4.720637e-4
GO:0021895	cerebral cortex neuron differentiation	4.776471e-4
GO:0070926	regulation of ATP:ADP antiporter activity	4.816598e-4
GO:0032774	RNA biosynthetic process	4.871460e-4
GO:0006351	transcription, DNA-dependent	4.871524e-4
GO:0006682	galactosylceramide biosynthetic process	5.029955e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	5.349784e-4
GO:0018993	somatic sex determination	5.471648e-4
GO:0021511	spinal cord patterning	5.606198e-4
GO:0032971	regulation of muscle filament sliding	5.618887e-4
GO:0043966	histone H3 acetylation	5.638967e-4
GO:0035136	forelimb morphogenesis	5.638967e-4
GO:0009186	deoxyribonucleoside diphosphate metabolic process	5.754298e-4
GO:0042711	maternal behavior	5.777058e-4
GO:0033566	gamma-tubulin complex localization	5.865470e-4
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	5.865470e-4
GO:0006384	transcription initiation from RNA polymerase III promoter	5.865470e-4
GO:0018872	arsonoacetate metabolic process	6.074206e-4
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	6.074206e-4
GO:0001514	selenocysteine incorporation	6.108896e-4
GO:0008588	release of cytoplasmic sequestered NF-kappaB	6.265050e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	6.300502e-4
GO:0003310	pancreatic A cell differentiation	6.306260e-4
GO:0045022	early endosome to late endosome transport	6.486230e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.598921e-4
GO:0003016	respiratory system process	6.755597e-4
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	6.856611e-4
GO:0021854	hypothalamus development	6.856611e-4
GO:0043687	post-translational protein modification	6.894201e-4
GO:0048570	notochord morphogenesis	7.080642e-4
GO:0021861	forebrain radial glial cell differentiation	7.083343e-4
GO:0008366	axon ensheathment	7.371380e-4
GO:0060716	labyrinthine layer blood vessel development	7.398247e-4
GO:0046113	nucleobase catabolic process	7.586989e-4
GO:0042167	heme catabolic process	7.670979e-4
GO:0061034	olfactory bulb mitral cell layer development	7.783123e-4
GO:0071726	cellular response to diacyl bacterial lipopeptide	7.783123e-4
GO:0042496	detection of diacyl bacterial lipopeptide	7.783123e-4
GO:0070193	synaptonemal complex organization	7.885141e-4
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	8.067858e-4
GO:0030853	negative regulation of granulocyte differentiation	8.207800e-4
GO:0043313	regulation of neutrophil degranulation	8.312430e-4
GO:0021513	spinal cord dorsal/ventral patterning	8.576311e-4
GO:0018193	peptidyl-amino acid modification	8.593292e-4
GO:0071816	tail-anchored membrane protein insertion into ER membrane	8.680573e-4
GO:0015824	proline transport	9.198563e-4
GO:0032205	negative regulation of telomere maintenance	9.371564e-4
GO:0006927	transformed cell apoptosis	9.592865e-4
GO:0043585	nose morphogenesis	9.592865e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	1.043678e-3
GO:0090370	negative regulation of cholesterol efflux	1.051543e-3
GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	1.051543e-3
GO:0071169	establishment of protein localization to chromatin	1.054024e-3
GO:0090245	axis elongation involved in somitogenesis	1.061484e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	1.061484e-3
GO:0071281	cellular response to iron ion	1.064484e-3
GO:0033687	osteoblast proliferation	1.174346e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.174346e-3
GO:0019637	organophosphate metabolic process	1.180053e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	1.194584e-3
GO:0000966	RNA 5'-end processing	1.203405e-3
GO:0032781	positive regulation of ATPase activity	1.208564e-3
GO:0021506	anterior neuropore closure	1.234195e-3
GO:0014916	regulation of lung blood pressure	1.234195e-3
GO:0032863	activation of Rac GTPase activity	1.236698e-3
GO:0035356	cellular triglyceride homeostasis	1.262630e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	1.284144e-3
GO:0043633	polyadenylation-dependent RNA catabolic process	1.291106e-3
GO:0006235	dTTP biosynthetic process	1.329297e-3
GO:0051289	protein homotetramerization	1.371794e-3
GO:0000019	regulation of mitotic recombination	1.389968e-3
GO:0009448	gamma-aminobutyric acid metabolic process	1.394599e-3
GO:0032230	positive regulation of synaptic transmission, GABAergic	1.397867e-3
GO:0017121	phospholipid scrambling	1.415008e-3
GO:0030225	macrophage differentiation	1.416378e-3
GO:0045820	negative regulation of glycolysis	1.434627e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.442436e-3
GO:0032661	regulation of interleukin-18 production	1.457744e-3
GO:0060021	palate development	1.459454e-3
GO:0048625	myoblast cell fate commitment	1.459912e-3
GO:0045444	fat cell differentiation	1.462597e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.470390e-3
GO:0048790	maintenance of presynaptic active zone structure	1.470390e-3
GO:0048841	regulation of axon extension involved in axon guidance	1.482556e-3
GO:0030237	female sex determination	1.484362e-3
GO:0060253	negative regulation of glial cell proliferation	1.494801e-3
GO:0001300	chronological cell aging	1.503554e-3
GO:0050771	negative regulation of axonogenesis	1.524167e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.567735e-3
GO:0046655	folic acid metabolic process	1.568803e-3
GO:0071727	cellular response to triacyl bacterial lipopeptide	1.570685e-3
GO:0042495	detection of triacyl bacterial lipopeptide	1.570685e-3
GO:0015840	urea transport	1.570685e-3
GO:0060073	micturition	1.734413e-3
GO:0002016	regulation of blood volume by renin-angiotensin	1.734413e-3
GO:0033084	regulation of immature T cell proliferation in thymus	1.734413e-3
GO:0050690	regulation of defense response to virus by virus	1.745302e-3
GO:0001508	regulation of action potential	1.753089e-3
GO:0042420	dopamine catabolic process	1.786290e-3
GO:0042472	inner ear morphogenesis	1.790571e-3
GO:0070914	UV-damage excision repair	1.793350e-3
GO:0010659	cardiac muscle cell apoptosis	1.795194e-3
GO:0014898	cardiac muscle hypertrophy in response to stress	1.832362e-3
GO:0009304	tRNA transcription	1.832362e-3
GO:0090231	regulation of spindle checkpoint	1.903447e-3
GO:0042471	ear morphogenesis	1.915106e-3
GO:0021683	cerebellar granular layer morphogenesis	1.932571e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.954165e-3
GO:0060318	definitive erythrocyte differentiation	1.964903e-3
GO:0007417	central nervous system development	2.013206e-3
GO:0043064	flagellum organization	2.030199e-3
GO:0051099	positive regulation of binding	2.030610e-3
GO:0021537	telencephalon development	2.031048e-3
GO:0043314	negative regulation of neutrophil degranulation	2.077894e-3
GO:0070593	dendrite self-avoidance	2.086030e-3
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	2.087320e-3
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	2.087320e-3
GO:0032738	positive regulation of interleukin-15 production	2.087320e-3
GO:0030322	stabilization of membrane potential	2.118603e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	2.118603e-3
GO:0010940	positive regulation of necrotic cell death	2.120785e-3
GO:0003417	growth plate cartilage development	2.120785e-3
GO:0060384	innervation	2.157900e-3
GO:0010960	magnesium ion homeostasis	2.184561e-3
GO:0050748	negative regulation of lipoprotein metabolic process	2.208739e-3
GO:0016445	somatic diversification of immunoglobulins	2.221661e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.232578e-3
GO:0010467	gene expression	2.243900e-3
GO:0090311	regulation of protein deacetylation	2.258922e-3
GO:0007619	courtship behavior	2.262983e-3
GO:2000171	negative regulation of dendrite development	2.328240e-3
GO:0021532	neural tube patterning	2.342848e-3
GO:0021562	vestibulocochlear nerve development	2.375941e-3
GO:0060179	male mating behavior	2.378128e-3
GO:0030223	neutrophil differentiation	2.384174e-3
GO:0048320	axial mesoderm formation	2.398168e-3
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	2.414146e-3
GO:0008045	motor axon guidance	2.447485e-3
GO:0048663	neuron fate commitment	2.473026e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	2.474239e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	2.474239e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	2.474239e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	2.474239e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.474239e-3
GO:0000917	barrier septum formation	2.474239e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	2.474239e-3
GO:0021586	pons maturation	2.474239e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.474239e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	2.474239e-3
GO:0006644	phospholipid metabolic process	2.484383e-3
GO:0042730	fibrinolysis	2.496599e-3
GO:0060083	smooth muscle contraction involved in micturition	2.557878e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.656673e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	2.665068e-3
GO:0018958	phenol-containing compound metabolic process	2.668239e-3
GO:0003093	regulation of glomerular filtration	2.720096e-3
GO:0007549	dosage compensation	2.720096e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	2.720096e-3
GO:0006289	nucleotide-excision repair	2.733152e-3
GO:0033152	immunoglobulin V(D)J recombination	2.739314e-3
GO:0002543	activation of blood coagulation via clotting cascade	2.797334e-3
GO:0060465	pharynx development	2.846440e-3
GO:0042942	D-serine transport	2.846440e-3
GO:0060611	mammary gland fat development	2.938887e-3
GO:0043461	proton-transporting ATP synthase complex assembly	2.938887e-3
GO:0060438	trachea development	2.940115e-3
GO:0006382	adenosine to inosine editing	2.964947e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	2.964947e-3
GO:2000627	positive regulation of miRNA catabolic process	2.998438e-3
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	2.998438e-3
GO:0050955	thermoception	2.998438e-3
GO:0000964	mitochondrial RNA 5'-end processing	2.998438e-3
GO:0043388	positive regulation of DNA binding	3.027219e-3
GO:0007635	chemosensory behavior	3.030284e-3
GO:0019226	transmission of nerve impulse	3.055741e-3
GO:0051891	positive regulation of cardioblast differentiation	3.084628e-3
GO:0045638	negative regulation of myeloid cell differentiation	3.087048e-3
GO:0032185	septin cytoskeleton organization	3.096483e-3
GO:0043467	regulation of generation of precursor metabolites and energy	3.182913e-3
GO:0030851	granulocyte differentiation	3.187937e-3
GO:0006781	succinyl-CoA pathway	3.191384e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	3.191384e-3
GO:0042450	arginine biosynthetic process via ornithine	3.191384e-3
GO:0030150	protein import into mitochondrial matrix	3.201558e-3
GO:0001672	regulation of chromatin assembly or disassembly	3.222836e-3
GO:0034776	response to histamine	3.223429e-3
GO:0071422	succinate transmembrane transport	3.223429e-3
GO:0008216	spermidine metabolic process	3.223429e-3
GO:0007623	circadian rhythm	3.288257e-3
GO:0006290	pyrimidine dimer repair	3.302071e-3
GO:0021636	trigeminal nerve morphogenesis	3.313900e-3
GO:0003014	renal system process	3.419691e-3
GO:0016197	endosome transport	3.439822e-3
GO:0035456	response to interferon-beta	3.466797e-3
GO:0043300	regulation of leukocyte degranulation	3.495674e-3
GO:0070340	detection of bacterial lipopeptide	3.524895e-3
GO:0035928	rRNA import into mitochondrion	3.524895e-3
GO:0045686	negative regulation of glial cell differentiation	3.534309e-3
GO:0002769	natural killer cell inhibitory signaling pathway	3.541948e-3
GO:0032409	regulation of transporter activity	3.547457e-3
GO:0035873	lactate transmembrane transport	3.600832e-3
GO:0060301	positive regulation of cytokine activity	3.647276e-3
GO:0042249	establishment of planar polarity of embryonic epithelium	3.647276e-3
GO:0009443	pyridoxal 5'-phosphate salvage	3.708243e-3
GO:0016233	telomere capping	3.728878e-3
GO:0003181	atrioventricular valve morphogenesis	3.754651e-3
GO:0021602	cranial nerve morphogenesis	3.825285e-3
GO:0042417	dopamine metabolic process	3.826827e-3
GO:0046500	S-adenosylmethionine metabolic process	3.847344e-3
GO:0003416	endochondral bone growth	3.848464e-3
GO:0042886	amide transport	3.848464e-3
GO:0008355	olfactory learning	3.898688e-3
GO:0001507	acetylcholine catabolic process in synaptic cleft	3.898688e-3
GO:0042093	T-helper cell differentiation	3.964202e-3
GO:0007270	neuron-neuron synaptic transmission	3.966450e-3
GO:0007386	compartment pattern specification	3.991467e-3
GO:0072529	pyrimidine-containing compound catabolic process	4.018357e-3
GO:0045920	negative regulation of exocytosis	4.049334e-3
GO:0032926	negative regulation of activin receptor signaling pathway	4.099021e-3
GO:0043534	blood vessel endothelial cell migration	4.122152e-3
GO:0055098	response to low-density lipoprotein particle stimulus	4.176855e-3
GO:0006208	pyrimidine base catabolic process	4.178550e-3
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	4.180459e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	4.285511e-3
GO:0021623	oculomotor nerve formation	4.300737e-3
GO:0051382	kinetochore assembly	4.300737e-3
GO:0003409	optic cup structural organization	4.300737e-3
GO:0003404	optic vesicle morphogenesis	4.300737e-3
GO:0032414	positive regulation of ion transmembrane transporter activity	4.303131e-3
GO:0071276	cellular response to cadmium ion	4.363677e-3
GO:0060839	endothelial cell fate commitment	4.363677e-3
GO:0010626	negative regulation of Schwann cell proliferation	4.363677e-3
GO:0016045	detection of bacterium	4.367888e-3
GO:0021697	cerebellar cortex formation	4.428426e-3
GO:0071899	negative regulation of estrogen receptor binding	4.474843e-3
GO:0003285	septum secundum development	4.502290e-3
GO:0010701	positive regulation of norepinephrine secretion	4.509209e-3
GO:0021517	ventral spinal cord development	4.510574e-3
GO:0032376	positive regulation of cholesterol transport	4.511451e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	4.512661e-3
GO:0048486	parasympathetic nervous system development	4.512661e-3
GO:0006659	phosphatidylserine biosynthetic process	4.523503e-3
GO:0015747	urate transport	4.589928e-3
GO:2000772	regulation of cellular senescence	4.630915e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	4.634573e-3
GO:0060019	radial glial cell differentiation	4.638387e-3
GO:0032648	regulation of interferon-beta production	4.691191e-3
GO:0070537	histone H2A K63-linked deubiquitination	4.694285e-3
GO:0010452	histone H3-K36 methylation	4.752022e-3
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	5.010445e-3
GO:0003278	apoptosis involved in heart morphogenesis	5.010445e-3
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	5.075455e-3
GO:0006575	cellular modified amino acid metabolic process	5.203936e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	5.311840e-3
GO:0022007	convergent extension involved in neural plate elongation	5.312142e-3
GO:0032481	positive regulation of type I interferon production	5.386183e-3
GO:0022898	regulation of transmembrane transporter activity	5.417556e-3
GO:0009151	purine deoxyribonucleotide metabolic process	5.435637e-3
GO:0008306	associative learning	5.438412e-3
GO:0030221	basophil differentiation	5.451227e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	5.486057e-3
GO:0021905	forebrain-midbrain boundary formation	5.594391e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	5.594391e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	5.594391e-3
GO:0003322	pancreatic A cell development	5.594391e-3
GO:0015820	leucine transport	5.634069e-3
GO:0046498	S-adenosylhomocysteine metabolic process	5.657676e-3
GO:0006083	acetate metabolic process	5.686389e-3
GO:0010587	miRNA catabolic process	5.686389e-3
GO:0043029	T cell homeostasis	5.777682e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	5.791889e-3
GO:0007588	excretion	5.850237e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	5.981980e-3
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	5.981980e-3
GO:0060166	olfactory pit development	5.989812e-3
GO:0003062	regulation of heart rate by chemical signal	5.989812e-3
GO:0048665	neuron fate specification	6.019664e-3
GO:0032764	negative regulation of mast cell cytokine production	6.062659e-3
GO:0006463	steroid hormone receptor complex assembly	6.177055e-3
GO:0021783	preganglionic parasympathetic nervous system development	6.179107e-3
GO:0090342	regulation of cell aging	6.197003e-3
GO:0001970	positive regulation of activation of membrane attack complex	6.240430e-3
GO:0050819	negative regulation of coagulation	6.263183e-3
GO:0042416	dopamine biosynthetic process	6.327298e-3
GO:0016180	snRNA processing	6.346593e-3
GO:0042312	regulation of vasodilation	6.352142e-3
GO:0061037	negative regulation of cartilage development	6.387312e-3
GO:0071402	cellular response to lipoprotein particle stimulus	6.387312e-3
GO:0017187	peptidyl-glutamic acid carboxylation	6.453752e-3
GO:0021797	forebrain anterior/posterior pattern specification	6.480641e-3
GO:0021681	cerebellar granular layer development	6.491982e-3
GO:0060306	regulation of membrane repolarization	6.592028e-3
GO:0021514	ventral spinal cord interneuron differentiation	6.593018e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	6.593390e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	6.652903e-3
GO:0010983	positive regulation of high-density lipoprotein particle clearance	6.652903e-3
GO:0060464	lung lobe formation	6.703347e-3
GO:0071800	podosome assembly	6.703347e-3
GO:0009235	cobalamin metabolic process	6.703347e-3
GO:0042537	benzene-containing compound metabolic process	6.703753e-3
GO:0019264	glycine biosynthetic process from serine	6.770894e-3
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	6.770894e-3
GO:0046886	positive regulation of hormone biosynthetic process	6.788448e-3
GO:0014832	urinary bladder smooth muscle contraction	6.805319e-3
GO:0010811	positive regulation of cell-substrate adhesion	6.894834e-3
GO:0010034	response to acetate	6.949181e-3
GO:0021533	cell differentiation in hindbrain	7.044352e-3
GO:0006173	dADP biosynthetic process	7.051650e-3
GO:0015734	taurine transport	7.051650e-3
GO:0035129	post-embryonic hindlimb morphogenesis	7.172700e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	7.172700e-3
GO:0006746	FADH2 metabolic process	7.172700e-3
GO:0051101	regulation of DNA binding	7.212751e-3
GO:0035767	endothelial cell chemotaxis	7.213494e-3
GO:0051532	regulation of NFAT protein import into nucleus	7.236644e-3
GO:0014909	smooth muscle cell migration	7.294859e-3
GO:0043967	histone H4 acetylation	7.341283e-3
GO:0035082	axoneme assembly	7.352007e-3
GO:0033327	Leydig cell differentiation	7.356778e-3
GO:0032461	positive regulation of protein oligomerization	7.371212e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	7.398816e-3
GO:0060406	positive regulation of penile erection	7.398816e-3
GO:0021761	limbic system development	7.427905e-3
GO:0006809	nitric oxide biosynthetic process	7.481538e-3
GO:0009744	response to sucrose stimulus	7.496842e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	7.516640e-3
GO:0006268	DNA unwinding involved in replication	7.516640e-3
GO:0006487	protein N-linked glycosylation	7.563188e-3
GO:0042823	pyridoxal phosphate biosynthetic process	7.566734e-3
GO:0019228	regulation of action potential in neuron	7.730497e-3
GO:0060764	cell-cell signaling involved in mammary gland development	7.763187e-3
GO:0021696	cerebellar cortex morphogenesis	7.777960e-3
GO:0021952	central nervous system projection neuron axonogenesis	7.865494e-3
GO:0090103	cochlea morphogenesis	7.871313e-3
GO:0021798	forebrain dorsal/ventral pattern formation	7.935849e-3
GO:0021587	cerebellum morphogenesis	8.037074e-3
GO:0035725	sodium ion transmembrane transport	8.056702e-3
GO:0017004	cytochrome complex assembly	8.190345e-3
GO:0070172	positive regulation of tooth mineralization	8.232241e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006139	nucleobase-containing compound metabolic process	1.281916e-13
GO:0044260	cellular macromolecule metabolic process	1.718884e-12
GO:0030488	tRNA methylation	1.463100e-11
GO:0010467	gene expression	2.460171e-11
GO:0016070	RNA metabolic process	2.636615e-11
GO:0090304	nucleic acid metabolic process	6.345604e-11
GO:0034641	cellular nitrogen compound metabolic process	1.826068e-10
GO:0006807	nitrogen compound metabolic process	1.388301e-9
GO:0032465	regulation of cytokinesis	1.405173e-9
GO:0032467	positive regulation of cytokinesis	4.763529e-9
GO:0032774	RNA biosynthetic process	5.149999e-9
GO:0008033	tRNA processing	6.437773e-9
GO:0043170	macromolecule metabolic process	7.687860e-9
GO:0044237	cellular metabolic process	9.860189e-9
GO:0006351	transcription, DNA-dependent	1.036565e-8
GO:0006400	tRNA modification	1.813981e-8
GO:0034614	cellular response to reactive oxygen species	3.113785e-8
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	5.147024e-8
GO:0051301	cell division	6.180686e-8
GO:0006779	porphyrin-containing compound biosynthetic process	6.636600e-8
GO:0055090	acylglycerol homeostasis	7.527995e-8
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.280123e-7
GO:0051890	regulation of cardioblast differentiation	1.342906e-7
GO:0071777	positive regulation of cell cycle cytokinesis	2.331043e-7
GO:0006783	heme biosynthetic process	2.647003e-7
GO:0035886	vascular smooth muscle cell differentiation	3.172631e-7
GO:0044238	primary metabolic process	3.806056e-7
GO:0019219	regulation of nucleobase-containing compound metabolic process	5.018926e-7
GO:0060575	intestinal epithelial cell differentiation	6.206279e-7
GO:0051171	regulation of nitrogen compound metabolic process	7.663784e-7
GO:0018202	peptidyl-histidine modification	9.708052e-7
GO:0051302	regulation of cell division	9.753220e-7
GO:0060440	trachea formation	1.206336e-6
GO:0060439	trachea morphogenesis	1.244517e-6
GO:0044249	cellular biosynthetic process	1.508801e-6
GO:0034645	cellular macromolecule biosynthetic process	1.758077e-6
GO:0006399	tRNA metabolic process	1.809596e-6
GO:0042168	heme metabolic process	1.821578e-6
GO:0090084	negative regulation of inclusion body assembly	3.670739e-6
GO:0002065	columnar/cuboidal epithelial cell differentiation	3.838857e-6
GO:0006778	porphyrin-containing compound metabolic process	4.163762e-6
GO:0035137	hindlimb morphogenesis	4.336975e-6
GO:0051781	positive regulation of cell division	4.605528e-6
GO:0008344	adult locomotory behavior	5.153067e-6
GO:0006355	regulation of transcription, DNA-dependent	5.326805e-6
GO:0009059	macromolecule biosynthetic process	5.486987e-6
GO:0001510	RNA methylation	5.607103e-6
GO:0009058	biosynthetic process	5.974163e-6
GO:0090086	negative regulation of protein deubiquitination	7.718065e-6
GO:0031326	regulation of cellular biosynthetic process	8.640983e-6
GO:0030902	hindbrain development	1.164266e-5
GO:0051252	regulation of RNA metabolic process	1.513465e-5
GO:0070301	cellular response to hydrogen peroxide	1.538226e-5
GO:0007224	smoothened signaling pathway	1.633105e-5
GO:0034470	ncRNA processing	1.637881e-5
GO:0048384	retinoic acid receptor signaling pathway	1.662611e-5
GO:0070588	calcium ion transmembrane transport	1.680690e-5
GO:0033013	tetrapyrrole metabolic process	1.780197e-5
GO:0006982	response to lipid hydroperoxide	1.787424e-5
GO:0060433	bronchus development	2.055499e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	2.244741e-5
GO:0009451	RNA modification	2.246129e-5
GO:0002663	positive regulation of B cell tolerance induction	2.259339e-5
GO:0009889	regulation of biosynthetic process	2.267361e-5
GO:0001570	vasculogenesis	2.461306e-5
GO:0061036	positive regulation of cartilage development	2.695612e-5
GO:0030520	estrogen receptor signaling pathway	2.919024e-5
GO:0022038	corpus callosum development	3.418416e-5
GO:0006390	transcription from mitochondrial promoter	3.864965e-5
GO:0060164	regulation of timing of neuron differentiation	3.952966e-5
GO:0070327	thyroid hormone transport	4.152975e-5
GO:0007628	adult walking behavior	4.450197e-5
GO:0030534	adult behavior	4.459789e-5
GO:0007420	brain development	4.520968e-5
GO:0060010	Sertoli cell fate commitment	4.538995e-5
GO:0043461	proton-transporting ATP synthase complex assembly	4.731276e-5
GO:0007256	activation of JNKK activity	4.838085e-5
GO:0006713	glucocorticoid catabolic process	4.902833e-5
GO:0051891	positive regulation of cardioblast differentiation	5.338628e-5
GO:0001706	endoderm formation	5.429678e-5
GO:0031323	regulation of cellular metabolic process	6.747645e-5
GO:0032862	activation of Rho GTPase activity	7.948260e-5
GO:0006261	DNA-dependent DNA replication	8.008945e-5
GO:0046426	negative regulation of JAK-STAT cascade	8.149324e-5
GO:0048554	positive regulation of metalloenzyme activity	8.378870e-5
GO:0065005	protein-lipid complex assembly	8.819913e-5
GO:0000959	mitochondrial RNA metabolic process	9.026795e-5
GO:0060438	trachea development	1.014864e-4
GO:0060319	primitive erythrocyte differentiation	1.082460e-4
GO:0046102	inosine metabolic process	1.213989e-4
GO:0021517	ventral spinal cord development	1.335691e-4
GO:0071585	detoxification of cadmium ion	1.348030e-4
GO:0009987	cellular process	1.366704e-4
GO:0032856	activation of Ras GTPase activity	1.374835e-4
GO:0060795	cell fate commitment involved in formation of primary germ layers	1.404359e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	1.423198e-4
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.429498e-4
GO:0008152	metabolic process	1.474718e-4
GO:0018193	peptidyl-amino acid modification	1.496351e-4
GO:0007398	ectoderm development	1.498264e-4
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.621769e-4
GO:0002227	innate immune response in mucosa	1.680682e-4
GO:0042697	menopause	1.758960e-4
GO:0061113	pancreas morphogenesis	1.789054e-4
GO:0010556	regulation of macromolecule biosynthetic process	1.926897e-4
GO:0046501	protoporphyrinogen IX metabolic process	1.929050e-4
GO:0051148	negative regulation of muscle cell differentiation	1.969321e-4
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	2.034916e-4
GO:0060983	epicardium-derived cardiac vascular smooth muscle cell differentiation	2.034916e-4
GO:0002651	positive regulation of tolerance induction to self antigen	2.089260e-4
GO:0034379	very-low-density lipoprotein particle assembly	2.163094e-4
GO:0070328	triglyceride homeostasis	2.178152e-4
GO:0001709	cell fate determination	2.231729e-4
GO:0070838	divalent metal ion transport	2.430774e-4
GO:0035116	embryonic hindlimb morphogenesis	2.500523e-4
GO:0050807	regulation of synapse organization	2.522433e-4
GO:0010468	regulation of gene expression	2.585031e-4
GO:0048511	rhythmic process	2.647113e-4
GO:0021756	striatum development	2.680423e-4
GO:0072511	divalent inorganic cation transport	2.709822e-4
GO:0048645	organ formation	2.952502e-4
GO:0031914	negative regulation of synaptic plasticity	2.972816e-4
GO:0010722	regulation of ferrochelatase activity	2.972816e-4
GO:0060216	definitive hemopoiesis	3.020129e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	3.051537e-4
GO:0060375	regulation of mast cell differentiation	3.051537e-4
GO:0021987	cerebral cortex development	3.345623e-4
GO:0045686	negative regulation of glial cell differentiation	3.445250e-4
GO:0032259	methylation	3.521189e-4
GO:0006396	RNA processing	3.712479e-4
GO:0090361	regulation of platelet-derived growth factor production	3.760155e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	3.779588e-4
GO:0032606	type I interferon production	3.853909e-4
GO:0008054	cyclin catabolic process	3.853909e-4
GO:0043491	protein kinase B signaling cascade	3.879987e-4
GO:0060591	chondroblast differentiation	3.912589e-4
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	3.987163e-4
GO:0001514	selenocysteine incorporation	3.987163e-4
GO:0002575	basophil chemotaxis	3.987163e-4
GO:0021954	central nervous system neuron development	4.010503e-4
GO:0048333	mesodermal cell differentiation	4.064216e-4
GO:0034660	ncRNA metabolic process	4.086131e-4
GO:0072337	modified amino acid transport	4.111763e-4
GO:0090085	regulation of protein deubiquitination	4.156824e-4
GO:0046591	embryonic leg joint morphogenesis	4.156824e-4
GO:0034616	response to laminar fluid shear stress	4.261237e-4
GO:2000736	regulation of stem cell differentiation	4.284405e-4
GO:0021562	vestibulocochlear nerve development	4.296158e-4
GO:0040032	post-embryonic body morphogenesis	4.336794e-4
GO:0015969	guanosine tetraphosphate metabolic process	4.700569e-4
GO:0071169	establishment of protein localization to chromatin	4.700569e-4
GO:0040015	negative regulation of multicellular organism growth	4.727609e-4
GO:2000741	positive regulation of mesenchymal stem cell differentiation	4.838353e-4
GO:0055091	phospholipid homeostasis	4.838353e-4
GO:0001824	blastocyst development	4.912011e-4
GO:0034599	cellular response to oxidative stress	5.096951e-4
GO:0010799	regulation of peptidyl-threonine phosphorylation	5.315174e-4
GO:0001710	mesodermal cell fate commitment	5.345996e-4
GO:0001704	formation of primary germ layer	5.353445e-4
GO:0009067	aspartate family amino acid biosynthetic process	5.438304e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	5.486204e-4
GO:0000722	telomere maintenance via recombination	5.636762e-4
GO:0001522	pseudouridine synthesis	5.641535e-4
GO:0008306	associative learning	5.711840e-4
GO:0051963	regulation of synapse assembly	6.024640e-4
GO:0080090	regulation of primary metabolic process	6.039898e-4
GO:0010896	regulation of triglyceride catabolic process	6.106116e-4
GO:0035136	forelimb morphogenesis	6.248966e-4
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	6.274408e-4
GO:0007498	mesoderm development	6.279725e-4
GO:0032321	positive regulation of Rho GTPase activity	6.329649e-4
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	6.532209e-4
GO:0033151	V(D)J recombination	6.567139e-4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.603561e-4
GO:0021953	central nervous system neuron differentiation	6.691314e-4
GO:0060644	mammary gland epithelial cell differentiation	6.735494e-4
GO:0006816	calcium ion transport	7.004035e-4
GO:0051005	negative regulation of lipoprotein lipase activity	7.042436e-4
GO:0072079	nephron tubule formation	7.055820e-4
GO:0007067	mitosis	7.072000e-4
GO:0046103	inosine biosynthetic process	7.177803e-4
GO:0060971	embryonic heart tube left/right pattern formation	7.177803e-4
GO:0008208	C21-steroid hormone catabolic process	7.177803e-4
GO:0006391	transcription initiation from mitochondrial promoter	7.177803e-4
GO:0006154	adenosine catabolic process	7.177803e-4
GO:0048665	neuron fate specification	7.221185e-4
GO:0007626	locomotory behavior	7.376649e-4
GO:0031398	positive regulation of protein ubiquitination	8.032461e-4
GO:0021781	glial cell fate commitment	8.247153e-4
GO:0044240	multicellular organismal lipid catabolic process	8.256835e-4
GO:0000086	G2/M transition of mitotic cell cycle	8.401964e-4
GO:0034220	ion transmembrane transport	8.558194e-4
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	8.600429e-4
GO:0033092	positive regulation of immature T cell proliferation in thymus	8.600429e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	8.693243e-4
GO:0019230	proprioception	8.693243e-4
GO:0031508	centromeric heterochromatin formation	8.893847e-4
GO:0018283	iron incorporation into metallo-sulfur cluster	9.021193e-4
GO:0060073	micturition	9.115390e-4
GO:0033136	serine phosphorylation of STAT3 protein	9.186302e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	9.186302e-4
GO:0006688	glycosphingolipid biosynthetic process	9.485545e-4
GO:0046543	development of secondary female sexual characteristics	9.734743e-4
GO:0090281	negative regulation of calcium ion import	9.945757e-4
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	9.945757e-4
GO:0071584	negative regulation of zinc ion import	9.945757e-4
GO:0045165	cell fate commitment	1.014587e-3
GO:0055024	regulation of cardiac muscle tissue development	1.038320e-3
GO:0072141	renal interstitial cell development	1.050057e-3
GO:0021549	cerebellum development	1.061184e-3
GO:0048266	behavioral response to pain	1.121695e-3
GO:0000087	M phase of mitotic cell cycle	1.148550e-3
GO:0021571	rhombomere 5 development	1.155207e-3
GO:0070574	cadmium ion transmembrane transport	1.155207e-3
GO:0097084	vascular smooth muscle cell development	1.191846e-3
GO:0010452	histone H3-K36 methylation	1.191846e-3
GO:0006207	'de novo' pyrimidine base biosynthetic process	1.191846e-3
GO:0032801	receptor catabolic process	1.201777e-3
GO:0003310	pancreatic A cell differentiation	1.202824e-3
GO:0031576	G2/M transition checkpoint	1.235150e-3
GO:0071241	cellular response to inorganic substance	1.243345e-3
GO:0043117	positive regulation of vascular permeability	1.266221e-3
GO:0018205	peptidyl-lysine modification	1.267807e-3
GO:0016570	histone modification	1.283617e-3
GO:0072078	nephron tubule morphogenesis	1.298382e-3
GO:0072190	ureter urothelium development	1.321715e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.328313e-3
GO:0043414	macromolecule methylation	1.343799e-3
GO:0051188	cofactor biosynthetic process	1.345377e-3
GO:0007403	glial cell fate determination	1.381757e-3
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	1.404688e-3
GO:0046604	positive regulation of mitotic centrosome separation	1.404688e-3
GO:2000682	positive regulation of rubidium ion transport	1.404688e-3
GO:0019556	histidine catabolic process to glutamate and formamide	1.404688e-3
GO:0035826	rubidium ion transport	1.404688e-3
GO:0035621	ER to Golgi ceramide transport	1.416464e-3
GO:0032232	negative regulation of actin filament bundle assembly	1.436268e-3
GO:0060038	cardiac muscle cell proliferation	1.441815e-3
GO:0033084	regulation of immature T cell proliferation in thymus	1.447443e-3
GO:0008211	glucocorticoid metabolic process	1.475704e-3
GO:0048505	regulation of timing of cell differentiation	1.479025e-3
GO:0034501	protein localization to kinetochore	1.489859e-3
GO:0030828	positive regulation of cGMP biosynthetic process	1.489859e-3
GO:0009086	methionine biosynthetic process	1.499376e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.499689e-3
GO:0061154	endothelial tube morphogenesis	1.499689e-3
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	1.499689e-3
GO:0044267	cellular protein metabolic process	1.505756e-3
GO:0022037	metencephalon development	1.523503e-3
GO:0042699	follicle-stimulating hormone signaling pathway	1.533474e-3
GO:0060419	heart growth	1.540494e-3
GO:0048389	intermediate mesoderm development	1.616829e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.616829e-3
GO:0061333	renal tubule morphogenesis	1.619497e-3
GO:0034442	regulation of lipoprotein oxidation	1.643271e-3
GO:0051004	regulation of lipoprotein lipase activity	1.648466e-3
GO:0007612	learning	1.657409e-3
GO:0048745	smooth muscle tissue development	1.682004e-3
GO:0006284	base-excision repair	1.682599e-3
GO:0046373	L-arabinose metabolic process	1.705136e-3
GO:0046130	purine ribonucleoside catabolic process	1.709667e-3
GO:0061088	regulation of sequestering of zinc ion	1.728549e-3
GO:0007610	behavior	1.764395e-3
GO:0016569	covalent chromatin modification	1.809547e-3
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	1.817795e-3
GO:0007517	muscle organ development	1.840538e-3
GO:0048541	Peyer's patch development	1.841180e-3
GO:0071877	regulation of adrenergic receptor signaling pathway	1.874152e-3
GO:0034635	glutathione transport	1.874152e-3
GO:0046952	ketone body catabolic process	1.874152e-3
GO:0045351	type I interferon biosynthetic process	1.890685e-3
GO:0045738	negative regulation of DNA repair	1.902542e-3
GO:0042501	serine phosphorylation of STAT protein	1.902542e-3
GO:0030970	retrograde protein transport, ER to cytosol	1.907052e-3
GO:0070836	caveola assembly	1.907052e-3
GO:0021758	putamen development	1.907052e-3
GO:0021757	caudate nucleus development	1.907052e-3
GO:0006481	C-terminal protein methylation	1.948420e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.952500e-3
GO:0050773	regulation of dendrite development	1.959943e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.967929e-3
GO:0046653	tetrahydrofolate metabolic process	1.991585e-3
GO:0055021	regulation of cardiac muscle tissue growth	2.044003e-3
GO:0000278	mitotic cell cycle	2.048413e-3
GO:0046777	protein autophosphorylation	2.113851e-3
GO:0021544	subpallium development	2.191227e-3
GO:0001574	ganglioside biosynthetic process	2.194996e-3
GO:0010464	regulation of mesenchymal cell proliferation	2.200317e-3
GO:0021631	optic nerve morphogenesis	2.271213e-3
GO:0007369	gastrulation	2.286362e-3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	2.308048e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.339144e-3
GO:0060434	bronchus morphogenesis	2.339144e-3
GO:0006383	transcription from RNA polymerase III promoter	2.339144e-3
GO:0006269	DNA replication, synthesis of RNA primer	2.339144e-3
GO:0010897	negative regulation of triglyceride catabolic process	2.339144e-3
GO:0006730	one-carbon metabolic process	2.351050e-3
GO:0042304	regulation of fatty acid biosynthetic process	2.363448e-3
GO:0060416	response to growth hormone stimulus	2.382842e-3
GO:0010574	regulation of vascular endothelial growth factor production	2.390922e-3
GO:0035887	aortic smooth muscle cell differentiation	2.393970e-3
GO:0021557	oculomotor nerve development	2.408167e-3
GO:0051965	positive regulation of synapse assembly	2.435907e-3
GO:0021603	cranial nerve formation	2.505486e-3
GO:0055012	ventricular cardiac muscle cell differentiation	2.505769e-3
GO:0048663	neuron fate commitment	2.509847e-3
GO:0001708	cell fate specification	2.566214e-3
GO:0060632	regulation of microtubule-based movement	2.581698e-3
GO:0051954	positive regulation of amine transport	2.605152e-3
GO:0006555	methionine metabolic process	2.618181e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.659393e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	2.659393e-3
GO:0033108	mitochondrial respiratory chain complex assembly	2.669284e-3
GO:0048793	pronephros development	2.722069e-3
GO:0060318	definitive erythrocyte differentiation	2.736834e-3
GO:0045333	cellular respiration	2.825572e-3
GO:0019941	modification-dependent protein catabolic process	2.833141e-3
GO:0031427	response to methotrexate	2.837694e-3
GO:2000739	regulation of mesenchymal stem cell differentiation	2.838534e-3
GO:0061326	renal tubule development	2.846056e-3
GO:0043632	modification-dependent macromolecule catabolic process	2.864416e-3
GO:0001832	blastocyst growth	2.892922e-3
GO:0009190	cyclic nucleotide biosynthetic process	2.922767e-3
GO:0010575	positive regulation vascular endothelial growth factor production	2.961429e-3
GO:0030431	sleep	3.046212e-3
GO:0007585	respiratory gaseous exchange	3.064227e-3
GO:0035964	COPI-coated vesicle budding	3.103309e-3
GO:0002645	positive regulation of tolerance induction	3.126211e-3
GO:0001833	inner cell mass cell proliferation	3.185062e-3
GO:0032836	glomerular basement membrane development	3.208236e-3
GO:2000772	regulation of cellular senescence	3.218354e-3
GO:0072080	nephron tubule development	3.237163e-3
GO:0035249	synaptic transmission, glutamatergic	3.247389e-3
GO:0015669	gas transport	3.316069e-3
GO:0043412	macromolecule modification	3.322983e-3
GO:0045768	positive regulation of anti-apoptosis	3.323808e-3
GO:0060192	negative regulation of lipase activity	3.337052e-3
GO:0072234	metanephric nephron tubule development	3.356549e-3
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	3.371173e-3
GO:0090185	negative regulation of kidney development	3.388742e-3
GO:0070172	positive regulation of tooth mineralization	3.388742e-3
GO:0072184	renal vesicle progenitor cell differentiation	3.501550e-3
GO:0072208	metanephric smooth muscle tissue development	3.501550e-3
GO:0072259	metanephric interstitial cell development	3.501550e-3
GO:0072169	specification of posterior mesonephric tubule identity	3.501550e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	3.501550e-3
GO:0072168	specification of anterior mesonephric tubule identity	3.501550e-3
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	3.501550e-3
GO:0048313	Golgi inheritance	3.501550e-3
GO:0071879	positive regulation of adrenergic receptor signaling pathway	3.501550e-3
GO:0048265	response to pain	3.526673e-3
GO:0045662	negative regulation of myoblast differentiation	3.575621e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	3.629544e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	3.629544e-3
GO:0046929	negative regulation of neurotransmitter secretion	3.633481e-3
GO:0045083	negative regulation of interleukin-12 biosynthetic process	3.633481e-3
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.717518e-3
GO:0035264	multicellular organism growth	3.758142e-3
GO:0061061	muscle structure development	3.758775e-3
GO:0090381	regulation of heart induction	3.795254e-3
GO:0021750	vestibular nucleus development	3.795254e-3
GO:0010936	negative regulation of macrophage cytokine production	3.795254e-3
GO:0021679	cerebellar molecular layer development	3.795254e-3
GO:0021590	cerebellum maturation	3.795254e-3
GO:0003093	regulation of glomerular filtration	3.799178e-3
GO:0035987	endodermal cell differentiation	3.802466e-3
GO:0021513	spinal cord dorsal/ventral patterning	3.802466e-3
GO:0021510	spinal cord development	3.840690e-3
GO:0042088	T-helper 1 type immune response	3.853835e-3
GO:0071780	mitotic cell cycle G2/M transition checkpoint	3.867917e-3
GO:0060492	lung induction	3.872543e-3
GO:0040023	establishment of nucleus localization	3.896236e-3
GO:0045601	regulation of endothelial cell differentiation	3.959273e-3
GO:0060711	labyrinthine layer development	3.966689e-3
GO:0072170	metanephric tubule development	3.973695e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	3.974828e-3
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	3.974828e-3
GO:0070079	histone H4-R3 demethylation	3.974828e-3
GO:0070078	histone H3-R2 demethylation	3.974828e-3
GO:0060217	hemangioblast cell differentiation	3.974828e-3
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	3.974828e-3
GO:0043148	mitotic spindle stabilization	3.974828e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	3.974828e-3
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	3.974828e-3
GO:0021935	cerebellar granule cell precursor tangential migration	3.974828e-3
GO:0035881	amacrine cell differentiation	4.066492e-3
GO:0060420	regulation of heart growth	4.094893e-3
GO:0043543	protein acylation	4.100073e-3
GO:0021578	hindbrain maturation	4.105230e-3
GO:0000212	meiotic spindle organization	4.105230e-3
GO:0070995	NADPH oxidation	4.149672e-3
GO:0021819	layer formation in cerebral cortex	4.149672e-3
GO:0048671	negative regulation of collateral sprouting	4.149672e-3
GO:0033554	cellular response to stress	4.153894e-3
GO:0060480	lung goblet cell differentiation	4.182440e-3
GO:0048239	negative regulation of DNA recombination at telomere	4.197607e-3
GO:0045645	positive regulation of eosinophil differentiation	4.197607e-3
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	4.197607e-3
GO:0070535	histone H2A K63-linked ubiquitination	4.197607e-3
GO:0048291	isotype switching to IgG isotypes	4.197607e-3
GO:0021572	rhombomere 6 development	4.197607e-3
GO:0006430	lysyl-tRNA aminoacylation	4.197607e-3
GO:0002368	B cell cytokine production	4.197607e-3
GO:0006741	NADP biosynthetic process	4.197607e-3
GO:0051349	positive regulation of lyase activity	4.213988e-3
GO:0030326	embryonic limb morphogenesis	4.214456e-3
GO:0051647	nucleus localization	4.233371e-3
GO:0008542	visual learning	4.261377e-3
GO:0055114	oxidation-reduction process	4.289862e-3
GO:0060043	regulation of cardiac muscle cell proliferation	4.305089e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	4.335122e-3
GO:0051138	positive regulation of NK T cell differentiation	4.383253e-3
GO:0002066	columnar/cuboidal epithelial cell development	4.383253e-3
GO:0001764	neuron migration	4.434219e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	4.450113e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	4.557487e-3
GO:0032911	negative regulation of transforming growth factor beta1 production	4.558391e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	4.558391e-3
GO:0072197	ureter morphogenesis	4.558391e-3
GO:0043353	enucleate erythrocyte differentiation	4.558391e-3
GO:0051322	anaphase	4.579770e-3
GO:0045722	positive regulation of gluconeogenesis	4.579770e-3
GO:0042542	response to hydrogen peroxide	4.640578e-3
GO:2000015	regulation of determination of dorsal identity	4.641839e-3
GO:0010724	regulation of definitive erythrocyte differentiation	4.641839e-3
GO:0051238	sequestering of metal ion	4.641839e-3
GO:0051899	membrane depolarization	4.688090e-3
GO:0033091	positive regulation of immature T cell proliferation	4.714009e-3
GO:0051028	mRNA transport	4.727814e-3
GO:0040034	regulation of development, heterochronic	4.783293e-3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	4.814643e-3
GO:0019222	regulation of metabolic process	4.821968e-3
GO:0000302	response to reactive oxygen species	4.854959e-3
GO:0033083	regulation of immature T cell proliferation	4.856274e-3
GO:0051154	negative regulation of striated muscle cell differentiation	4.909682e-3
GO:0072148	epithelial cell fate commitment	4.909682e-3
GO:0007052	mitotic spindle organization	4.909682e-3
GO:0009060	aerobic respiration	4.965126e-3
GO:0007519	skeletal muscle tissue development	5.007841e-3
GO:0006511	ubiquitin-dependent protein catabolic process	5.080486e-3
GO:0048537	mucosal-associated lymphoid tissue development	5.131764e-3
GO:0007379	segment specification	5.131764e-3
GO:0060083	smooth muscle contraction involved in micturition	5.190190e-3
GO:0051016	barbed-end actin filament capping	5.213340e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	5.246491e-3
GO:0055117	regulation of cardiac muscle contraction	5.269736e-3
GO:0002639	positive regulation of immunoglobulin production	5.301183e-3
GO:0055069	zinc ion homeostasis	5.340216e-3
GO:0046686	response to cadmium ion	5.343569e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	5.373592e-3
GO:0060215	primitive hemopoiesis	5.373592e-3
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	5.384151e-3
GO:0050803	regulation of synapse structure and activity	5.433836e-3
GO:0051726	regulation of cell cycle	5.462034e-3
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	5.467604e-3
GO:0042744	hydrogen peroxide catabolic process	5.574959e-3
GO:0043647	inositol phosphate metabolic process	5.604460e-3
GO:0050748	negative regulation of lipoprotein metabolic process	5.604627e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	5.604627e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	5.609394e-3
GO:0006599	phosphagen metabolic process	5.610377e-3
GO:0008631	induction of apoptosis by oxidative stress	5.642484e-3
GO:0060484	lung-associated mesenchyme development	5.754187e-3
GO:0021542	dentate gyrus development	5.770853e-3
GO:0009247	glycolipid biosynthetic process	5.770853e-3
GO:0060998	regulation of dendritic spine development	5.805931e-3
GO:2000124	regulation of endocannabinoid signaling pathway	5.837073e-3
GO:0006312	mitotic recombination	5.837073e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.911959e-3
GO:0042268	regulation of cytolysis	5.926822e-3
GO:0060977	coronary vasculature morphogenesis	5.945109e-3
GO:0051924	regulation of calcium ion transport	5.947969e-3
GO:0031572	G2/M transition DNA damage checkpoint	6.010748e-3
GO:0071299	cellular response to vitamin A	6.019868e-3
GO:0045908	negative regulation of vasodilation	6.086689e-3
GO:0072172	mesonephric tubule formation	6.132064e-3
GO:0001892	embryonic placenta development	6.199841e-3
GO:0051597	response to methylmercury	6.224972e-3
GO:0034101	erythrocyte homeostasis	6.274163e-3
GO:0033344	cholesterol efflux	6.339038e-3
GO:0071300	cellular response to retinoic acid	6.341522e-3
GO:0048285	organelle fission	6.427136e-3
GO:0046341	CDP-diacylglycerol metabolic process	6.441527e-3
GO:0045759	negative regulation of action potential	6.441527e-3
GO:0006438	valyl-tRNA aminoacylation	6.441527e-3
GO:0072207	metanephric epithelium development	6.449082e-3
GO:0035307	positive regulation of protein dephosphorylation	6.511522e-3
GO:0033152	immunoglobulin V(D)J recombination	6.511522e-3
GO:0018130	heterocycle biosynthetic process	6.579571e-3
GO:0046425	regulation of JAK-STAT cascade	6.639011e-3
GO:2000685	positive regulation of cellular response to X-ray	6.690858e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	6.690858e-3
GO:0035988	chondrocyte proliferation	6.690858e-3
GO:2001038	regulation of cellular response to drug	6.690858e-3
GO:0031052	chromosome breakage	6.690858e-3
GO:0035978	histone H2A-S139 phosphorylation	6.690858e-3
GO:0003131	mesodermal-endodermal cell signaling	6.690858e-3
GO:0035166	post-embryonic hemopoiesis	6.690858e-3
GO:0046148	pigment biosynthetic process	6.702069e-3
GO:0021535	cell migration in hindbrain	6.713113e-3