Novel motif:118

name:	motif118_AATCCGGCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0031167	rRNA methylation	1.880964e-8
GO:0009744	response to sucrose stimulus	8.964676e-8
GO:0010871	negative regulation of receptor biosynthetic process	2.944896e-7
GO:0000154	rRNA modification	3.165911e-7
GO:0043457	regulation of cellular respiration	4.277974e-7
GO:0006391	transcription initiation from mitochondrial promoter	4.523933e-7
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	5.647065e-7
GO:0009589	detection of UV	5.647065e-7
GO:0015742	alpha-ketoglutarate transport	6.789946e-7
GO:0070489	T cell aggregation	8.424625e-7
GO:0006290	pyrimidine dimer repair	1.488336e-6
GO:0042137	sequestering of neurotransmitter	1.776669e-6
GO:0051152	positive regulation of smooth muscle cell differentiation	2.922363e-6
GO:0046732	active induction of host immune response by virus	3.689583e-6
GO:0002456	T cell mediated immunity	3.956429e-6
GO:0051383	kinetochore organization	4.309302e-6
GO:0051382	kinetochore assembly	5.495637e-6
GO:0007168	receptor guanylyl cyclase signaling pathway	5.827152e-6
GO:0006261	DNA-dependent DNA replication	6.694707e-6
GO:0055099	response to high density lipoprotein particle stimulus	7.271615e-6
GO:0000088	mitotic prophase	9.953653e-6
GO:0060364	frontal suture morphogenesis	1.246552e-5
GO:0050765	negative regulation of phagocytosis	1.868442e-5
GO:0021557	oculomotor nerve development	2.162131e-5
GO:0042481	regulation of odontogenesis	2.195531e-5
GO:0043163	cell envelope organization	2.272029e-5
GO:0031627	telomeric loop formation	2.324623e-5
GO:0071593	lymphocyte aggregation	2.493557e-5
GO:0006540	glutamate decarboxylation to succinate	3.280186e-5
GO:0006817	phosphate ion transport	3.325799e-5
GO:0071109	superior temporal gyrus development	3.833555e-5
GO:0032801	receptor catabolic process	3.953051e-5
GO:0050783	cocaine metabolic process	4.315896e-5
GO:0045773	positive regulation of axon extension	4.392699e-5
GO:0051534	negative regulation of NFAT protein import into nucleus	4.461664e-5
GO:0007031	peroxisome organization	4.861141e-5
GO:0021783	preganglionic parasympathetic nervous system development	4.898915e-5
GO:0021602	cranial nerve morphogenesis	4.989855e-5
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	5.498782e-5
GO:2000627	positive regulation of miRNA catabolic process	5.498782e-5
GO:0018352	protein-pyridoxal-5-phosphate linkage	5.498782e-5
GO:0000964	mitochondrial RNA 5'-end processing	5.498782e-5
GO:0016082	synaptic vesicle priming	5.825721e-5
GO:0051261	protein depolymerization	6.081229e-5
GO:0070537	histone H2A K63-linked deubiquitination	6.503818e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	6.875841e-5
GO:0009817	defense response to fungus, incompatible interaction	6.875841e-5
GO:0090086	negative regulation of protein deubiquitination	6.923214e-5
GO:0006173	dADP biosynthetic process	6.923214e-5
GO:0090231	regulation of spindle checkpoint	6.931715e-5
GO:0060560	developmental growth involved in morphogenesis	7.004584e-5
GO:0048075	positive regulation of eye pigmentation	7.093892e-5
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	8.048225e-5
GO:0021603	cranial nerve formation	8.407294e-5
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	8.589728e-5
GO:0006682	galactosylceramide biosynthetic process	9.383044e-5
GO:0031081	nuclear pore distribution	1.099125e-4
GO:0043316	cytotoxic T cell degranulation	1.109111e-4
GO:0032096	negative regulation of response to food	1.131812e-4
GO:0021511	spinal cord patterning	1.207624e-4
GO:0031848	protection from non-homologous end joining at telomere	1.210428e-4
GO:0032740	positive regulation of interleukin-17 production	1.215070e-4
GO:0046730	induction of host immune response by virus	1.250924e-4
GO:0043249	erythrocyte maturation	1.275446e-4
GO:0032108	negative regulation of response to nutrient levels	1.276138e-4
GO:0034508	centromere complex assembly	1.277937e-4
GO:0032099	negative regulation of appetite	1.277937e-4
GO:0051148	negative regulation of muscle cell differentiation	1.289908e-4
GO:0045116	protein neddylation	1.425757e-4
GO:0048102	autophagic cell death	1.425757e-4
GO:0006538	glutamate catabolic process	1.425757e-4
GO:0033034	positive regulation of myeloid cell apoptosis	1.512208e-4
GO:0090311	regulation of protein deacetylation	1.541805e-4
GO:0043633	polyadenylation-dependent RNA catabolic process	1.623632e-4
GO:0000965	mitochondrial RNA 3'-end processing	1.623632e-4
GO:0000958	mitochondrial mRNA catabolic process	1.623632e-4
GO:0000962	positive regulation of mitochondrial RNA catabolic process	1.623632e-4
GO:0044089	positive regulation of cellular component biogenesis	1.625710e-4
GO:0043628	ncRNA 3'-end processing	1.654562e-4
GO:0016058	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	1.759561e-4
GO:0022400	regulation of rhodopsin mediated signaling pathway	1.759561e-4
GO:0006208	pyrimidine base catabolic process	1.863446e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.989164e-4
GO:0048639	positive regulation of developmental growth	2.126581e-4
GO:0010891	negative regulation of sequestering of triglyceride	2.148007e-4
GO:0015812	gamma-aminobutyric acid transport	2.166933e-4
GO:0060603	mammary gland duct morphogenesis	2.182948e-4
GO:0006273	lagging strand elongation	2.230210e-4
GO:0030516	regulation of axon extension	2.364681e-4
GO:0021599	abducens nerve formation	2.445596e-4
GO:0016191	synaptic vesicle uncoating	2.445596e-4
GO:0007634	optokinetic behavior	2.445596e-4
GO:0015809	arginine transport	2.536863e-4
GO:0000089	mitotic metaphase	2.640831e-4
GO:0000085	G2 phase of mitotic cell cycle	2.654731e-4
GO:0061101	neuroendocrine cell differentiation	2.761768e-4
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	2.792394e-4
GO:0050805	negative regulation of synaptic transmission	2.830397e-4
GO:0006369	termination of RNA polymerase II transcription	2.904741e-4
GO:0051898	negative regulation of protein kinase B signaling cascade	2.919720e-4
GO:0032331	negative regulation of chondrocyte differentiation	2.969219e-4
GO:0031536	positive regulation of exit from mitosis	3.079658e-4
GO:0001522	pseudouridine synthesis	3.079658e-4
GO:0042117	monocyte activation	3.298856e-4
GO:0071105	response to interleukin-11	3.478891e-4
GO:0043653	mitochondrial fragmentation involved in apoptosis	3.567228e-4
GO:0030853	negative regulation of granulocyte differentiation	3.589367e-4
GO:0003140	determination of left/right asymmetry in lateral mesoderm	3.669391e-4
GO:0051322	anaphase	3.687249e-4
GO:0006268	DNA unwinding involved in replication	3.744145e-4
GO:0010823	negative regulation of mitochondrion organization	3.779253e-4
GO:0046113	nucleobase catabolic process	3.783958e-4
GO:0021513	spinal cord dorsal/ventral patterning	3.828343e-4
GO:0051965	positive regulation of synapse assembly	4.054306e-4
GO:0000959	mitochondrial RNA metabolic process	4.148846e-4
GO:0001558	regulation of cell growth	4.262697e-4
GO:0007000	nucleolus organization	4.384864e-4
GO:0000022	mitotic spindle elongation	4.384864e-4
GO:0034623	cellular macromolecular complex disassembly	4.411470e-4
GO:0016139	glycoside catabolic process	4.455775e-4
GO:0010936	negative regulation of macrophage cytokine production	4.540984e-4
GO:0070358	actin polymerization-dependent cell motility	4.634194e-4
GO:0002309	T cell proliferation involved in immune response	4.719572e-4
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	4.769353e-4
GO:0009451	RNA modification	4.885772e-4
GO:0002513	tolerance induction to self antigen	5.060161e-4
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	5.274818e-4
GO:0071173	spindle assembly checkpoint	5.317449e-4
GO:0050432	catecholamine secretion	5.327348e-4
GO:0061102	stomach neuroendocrine cell differentiation	5.371919e-4
GO:0061100	lung neuroendocrine cell differentiation	5.371919e-4
GO:0071259	cellular response to magnetism	5.371919e-4
GO:0061104	adrenal chromaffin cell differentiation	5.371919e-4
GO:0061103	carotid body glomus cell differentiation	5.371919e-4
GO:0003359	noradrenergic neuron fate commitment	5.371919e-4
GO:0060165	regulation of timing of subpallium neuron differentiation	5.371919e-4
GO:0007400	neuroblast fate determination	5.371919e-4
GO:0048073	regulation of eye pigmentation	5.371919e-4
GO:0060163	subpallium neuron fate commitment	5.371919e-4
GO:0008334	histone mRNA metabolic process	5.381636e-4
GO:0007051	spindle organization	5.542627e-4
GO:0071174	mitotic cell cycle spindle checkpoint	5.669992e-4
GO:0021569	rhombomere 3 development	5.722740e-4
GO:0032984	macromolecular complex disassembly	5.755198e-4
GO:0031577	spindle checkpoint	5.968213e-4
GO:2000534	positive regulation of renal albumin absorption	5.989993e-4
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	5.989993e-4
GO:0070994	detection of oxidative stress	5.989993e-4
GO:2000461	negative regulation of eukaryotic cell surface binding	5.989993e-4
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	5.989993e-4
GO:0048627	myoblast development	6.014919e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	6.116987e-4
GO:0035880	embryonic nail plate morphogenesis	6.244621e-4
GO:0006625	protein targeting to peroxisome	6.263872e-4
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	6.512660e-4
GO:0045649	regulation of macrophage differentiation	6.789031e-4
GO:0043129	surfactant homeostasis	6.849619e-4
GO:0052509	positive regulation by symbiont of host defense response	6.905140e-4
GO:0045820	negative regulation of glycolysis	7.180013e-4
GO:0006379	mRNA cleavage	7.180013e-4
GO:0021623	oculomotor nerve formation	7.200958e-4
GO:0003409	optic cup structural organization	7.200958e-4
GO:0003404	optic vesicle morphogenesis	7.200958e-4
GO:0061387	regulation of extent of cell growth	7.361449e-4
GO:0002418	immune response to tumor cell	7.436272e-4
GO:0060465	pharynx development	7.436272e-4
GO:0043624	cellular protein complex disassembly	7.691840e-4
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	7.709876e-4
GO:0071281	cellular response to iron ion	7.745258e-4
GO:0051970	negative regulation of transmission of nerve impulse	7.892388e-4
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	7.987271e-4
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	7.987271e-4
GO:0006427	histidyl-tRNA aminoacylation	7.987271e-4
GO:0032738	positive regulation of interleukin-15 production	7.987271e-4
GO:0048486	parasympathetic nervous system development	7.988989e-4
GO:0034080	CenH3-containing nucleosome assembly at centromere	7.988989e-4
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	8.177327e-4
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	8.177327e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.177327e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	8.177327e-4
GO:0051926	negative regulation of calcium ion transport	8.314330e-4
GO:0032812	positive regulation of epinephrine secretion	8.392231e-4
GO:0070253	somatostatin secretion	8.392231e-4
GO:0046683	response to organophosphorus	8.436078e-4
GO:0021545	cranial nerve development	8.496552e-4
GO:0031063	regulation of histone deacetylation	8.609251e-4
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	8.671099e-4
GO:0045653	negative regulation of megakaryocyte differentiation	8.716132e-4
GO:0060876	semicircular canal formation	9.165486e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	9.165486e-4
GO:0070574	cadmium ion transmembrane transport	9.271345e-4
GO:0017085	response to insecticide	9.440765e-4
GO:0032845	negative regulation of homeostatic process	9.441110e-4
GO:0007228	positive regulation of hh target transcription factor activity	9.522179e-4
GO:0043981	histone H4-K5 acetylation	9.703993e-4
GO:0043982	histone H4-K8 acetylation	9.703993e-4
GO:0090312	positive regulation of protein deacetylation	9.851551e-4
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.002847e-3
GO:0043932	ossification involved in bone remodeling	1.005937e-3
GO:0046724	oxalic acid secretion	1.027074e-3
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	1.027074e-3
GO:0043241	protein complex disassembly	1.031316e-3
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	1.049466e-3
GO:0015889	cobalamin transport	1.049466e-3
GO:0034436	glycoprotein transport	1.058424e-3
GO:0090085	regulation of protein deubiquitination	1.058424e-3
GO:0009720	detection of hormone stimulus	1.058424e-3
GO:0030573	bile acid catabolic process	1.067874e-3
GO:0060459	left lung development	1.079875e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.103409e-3
GO:0032660	regulation of interleukin-17 production	1.157529e-3
GO:0018108	peptidyl-tyrosine phosphorylation	1.175510e-3
GO:0035115	embryonic forelimb morphogenesis	1.186386e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.190827e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.211093e-3
GO:0010739	positive regulation of protein kinase A signaling cascade	1.224320e-3
GO:2000077	negative regulation of type B pancreatic cell development	1.286630e-3
GO:0006420	arginyl-tRNA aminoacylation	1.286630e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.310358e-3
GO:0043574	peroxisomal transport	1.326104e-3
GO:0000731	DNA synthesis involved in DNA repair	1.327876e-3
GO:0045839	negative regulation of mitosis	1.334397e-3
GO:0031055	chromatin remodeling at centromere	1.345820e-3
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	1.355073e-3
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	1.355073e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	1.355073e-3
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	1.355073e-3
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	1.355073e-3
GO:0080125	multicellular structure septum development	1.355073e-3
GO:0007502	digestive tract mesoderm development	1.355073e-3
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	1.355073e-3
GO:0014858	positive regulation of skeletal muscle cell proliferation	1.355073e-3
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	1.355073e-3
GO:0046534	positive regulation of photoreceptor cell differentiation	1.355073e-3
GO:0022037	metencephalon development	1.356395e-3
GO:0070206	protein trimerization	1.398495e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.423822e-3
GO:0022616	DNA strand elongation	1.435988e-3
GO:0060447	bud outgrowth involved in lung branching	1.460716e-3
GO:0008361	regulation of cell size	1.497281e-3
GO:0031645	negative regulation of neurological system process	1.514767e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.533228e-3
GO:0018212	peptidyl-tyrosine modification	1.538934e-3
GO:0070172	positive regulation of tooth mineralization	1.573638e-3
GO:0006013	mannose metabolic process	1.588802e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.596990e-3
GO:0021546	rhombomere development	1.617242e-3
GO:0070207	protein homotrimerization	1.617557e-3
GO:0019083	viral transcription	1.653667e-3
GO:0018065	protein-cofactor linkage	1.691000e-3
GO:0010887	negative regulation of cholesterol storage	1.698060e-3
GO:0060579	ventral spinal cord interneuron fate commitment	1.699102e-3
GO:0006272	leading strand elongation	1.708729e-3
GO:0046532	regulation of photoreceptor cell differentiation	1.721607e-3
GO:0051586	positive regulation of dopamine uptake	1.768199e-3
GO:0010722	regulation of ferrochelatase activity	1.768199e-3
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	1.789576e-3
GO:0006528	asparagine metabolic process	1.789576e-3
GO:0072298	regulation of metanephric glomerulus development	1.812750e-3
GO:0045684	positive regulation of epidermis development	1.813801e-3
GO:0044341	sodium-dependent phosphate transport	1.820138e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	1.834717e-3
GO:0010043	response to zinc ion	1.877550e-3
GO:0045604	regulation of epidermal cell differentiation	1.881569e-3
GO:0010637	negative regulation of mitochondrial fusion	1.945116e-3
GO:0071279	cellular response to cobalt ion	1.945116e-3
GO:0030311	poly-N-acetyllactosamine biosynthetic process	1.945116e-3
GO:0001957	intramembranous ossification	1.965664e-3
GO:0060659	nipple sheath formation	1.977622e-3
GO:0060649	mammary gland bud elongation	1.977622e-3
GO:0043525	positive regulation of neuron apoptosis	1.983835e-3
GO:0000712	resolution of meiotic recombination intermediates	1.996118e-3
GO:0007019	microtubule depolymerization	2.036111e-3
GO:0010832	negative regulation of myotube differentiation	2.040480e-3
GO:0045776	negative regulation of blood pressure	2.062724e-3
GO:0018027	peptidyl-lysine dimethylation	2.131984e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	2.154971e-3
GO:0031860	telomeric 3' overhang formation	2.176356e-3
GO:2000009	negative regulation of protein localization at cell surface	2.176356e-3
GO:0071422	succinate transmembrane transport	2.216892e-3
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	2.302978e-3
GO:0014051	gamma-aminobutyric acid secretion	2.302978e-3
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	2.416355e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	2.416355e-3
GO:0090084	negative regulation of inclusion body assembly	2.487436e-3
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	2.525576e-3
GO:0009066	aspartate family amino acid metabolic process	2.578852e-3
GO:0021592	fourth ventricle development	2.632474e-3
GO:0046501	protoporphyrinogen IX metabolic process	2.679871e-3
GO:0071585	detoxification of cadmium ion	2.689748e-3
GO:0006270	DNA-dependent DNA replication initiation	2.692537e-3
GO:0048840	otolith development	2.736897e-3
GO:0048714	positive regulation of oligodendrocyte differentiation	2.874974e-3
GO:0071549	cellular response to dexamethasone stimulus	2.889922e-3
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	2.891072e-3
GO:0000090	mitotic anaphase	2.938302e-3
GO:0006271	DNA strand elongation involved in DNA replication	2.964323e-3
GO:0034616	response to laminar fluid shear stress	2.964323e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	3.053008e-3
GO:0070060	'de novo' actin filament nucleation	3.073662e-3
GO:0006529	asparagine biosynthetic process	3.073662e-3
GO:0045200	establishment of neuroblast polarity	3.093603e-3
GO:0009229	thiamine diphosphate biosynthetic process	3.093603e-3
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	3.093603e-3
GO:0002719	negative regulation of cytokine production involved in immune response	3.112119e-3
GO:0046425	regulation of JAK-STAT cascade	3.118795e-3
GO:0060516	primary prostatic bud elongation	3.120438e-3
GO:0071850	mitotic cell cycle arrest	3.215995e-3
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	3.215995e-3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	3.303992e-3
GO:0045792	negative regulation of cell size	3.347794e-3
GO:0090232	positive regulation of spindle checkpoint	3.347794e-3
GO:0006546	glycine catabolic process	3.347794e-3
GO:0048859	formation of anatomical boundary	3.370931e-3
GO:0007418	ventral midline development	3.370931e-3
GO:0001553	luteinization	3.391321e-3
GO:0018026	peptidyl-lysine monomethylation	3.411775e-3
GO:0030308	negative regulation of cell growth	3.446284e-3
GO:0021521	ventral spinal cord interneuron specification	3.453076e-3
GO:0031297	replication fork processing	3.464605e-3
GO:0019049	evasion of host defenses by virus	3.464605e-3
GO:0042482	positive regulation of odontogenesis	3.502283e-3
GO:0070925	organelle assembly	3.535627e-3
GO:0015701	bicarbonate transport	3.579874e-3
GO:0034214	protein hexamerization	3.588819e-3
GO:0033058	directional locomotion	3.588819e-3
GO:0019058	viral infectious cycle	3.601039e-3
GO:0006260	DNA replication	3.632540e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	3.634728e-3
GO:0060611	mammary gland fat development	3.634728e-3
GO:0006415	translational termination	3.671608e-3
GO:0019695	choline metabolic process	3.680622e-3
GO:0060349	bone morphogenesis	3.702296e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	3.709831e-3
GO:0043268	positive regulation of potassium ion transport	3.779267e-3
GO:0016233	telomere capping	3.862735e-3
GO:0033004	negative regulation of mast cell activation	3.910611e-3
GO:0031427	response to methotrexate	3.923223e-3
GO:0035458	cellular response to interferon-beta	3.926343e-3
GO:0031123	RNA 3'-end processing	3.952169e-3
GO:0002052	positive regulation of neuroblast proliferation	4.017832e-3
GO:0021549	cerebellum development	4.019104e-3
GO:0002369	T cell cytokine production	4.023294e-3
GO:0010742	macrophage derived foam cell differentiation	4.023294e-3
GO:0031125	rRNA 3'-end processing	4.040336e-3
GO:0032571	response to vitamin K	4.040336e-3
GO:0021568	rhombomere 2 development	4.040336e-3
GO:0016539	intein-mediated protein splicing	4.040336e-3
GO:0009263	deoxyribonucleotide biosynthetic process	4.087288e-3
GO:0006105	succinate metabolic process	4.107183e-3
GO:0016560	protein import into peroxisome matrix, docking	4.130400e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.130400e-3
GO:0032463	negative regulation of protein homooligomerization	4.136237e-3
GO:0090218	positive regulation of lipid kinase activity	4.196352e-3
GO:0033205	cell cycle cytokinesis	4.208411e-3
GO:0021903	rostrocaudal neural tube patterning	4.228068e-3
GO:0032864	activation of Cdc42 GTPase activity	4.316854e-3
GO:0051320	S phase	4.346831e-3
GO:0050769	positive regulation of neurogenesis	4.431811e-3
GO:0048705	skeletal system morphogenesis	4.547801e-3
GO:0051532	regulation of NFAT protein import into nucleus	4.550372e-3
GO:0006828	manganese ion transport	4.550372e-3
GO:0060484	lung-associated mesenchyme development	4.559578e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	4.574026e-3
GO:0042780	tRNA 3'-end processing	4.614312e-3
GO:0010734	negative regulation of protein glutathionylation	4.614312e-3
GO:0001778	plasma membrane repair	4.620432e-3
GO:0070086	ubiquitin-dependent endocytosis	4.627018e-3
GO:0050931	pigment cell differentiation	4.702177e-3
GO:0030917	midbrain-hindbrain boundary development	4.758917e-3
GO:0045682	regulation of epidermis development	4.796301e-3
GO:0006607	NLS-bearing substrate import into nucleus	4.807264e-3
GO:0021697	cerebellar cortex formation	4.817974e-3
GO:0044070	regulation of anion transport	4.863494e-3
GO:0032922	circadian regulation of gene expression	4.886460e-3
GO:0021526	medial motor column neuron differentiation	4.902694e-3
GO:0021658	rhombomere 3 morphogenesis	4.933848e-3
GO:0015886	heme transport	5.089333e-3
GO:0008210	estrogen metabolic process	5.095822e-3
GO:0048808	male genitalia morphogenesis	5.133366e-3
GO:0007262	STAT protein import into nucleus	5.135847e-3
GO:0021523	somatic motor neuron differentiation	5.135847e-3
GO:0005983	starch catabolic process	5.135925e-3
GO:0006172	ADP biosynthetic process	5.159280e-3
GO:0000966	RNA 5'-end processing	5.159280e-3
GO:0030953	astral microtubule organization	5.219233e-3
GO:0002357	defense response to tumor cell	5.325004e-3
GO:0008057	eye pigment granule organization	5.468644e-3
GO:0046031	ADP metabolic process	5.482145e-3
GO:0015844	monoamine transport	5.482957e-3
GO:0033007	negative regulation of mast cell activation involved in immune response	5.524184e-3
GO:0001579	medium-chain fatty acid transport	5.583526e-3
GO:0060648	mammary gland bud morphogenesis	5.603128e-3
GO:0031065	positive regulation of histone deacetylation	5.755708e-3
GO:0030852	regulation of granulocyte differentiation	5.836010e-3
GO:0035284	brain segmentation	5.993242e-3
GO:0072075	metanephric mesenchyme development	6.049360e-3
GO:0051154	negative regulation of striated muscle cell differentiation	6.087865e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	6.132594e-3
GO:0021587	cerebellum morphogenesis	6.239969e-3
GO:0003416	endochondral bone growth	6.242240e-3
GO:0045616	regulation of keratinocyte differentiation	6.277464e-3
GO:0016137	glycoside metabolic process	6.484638e-3
GO:0015802	basic amino acid transport	6.565195e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	6.617607e-3
GO:0030309	poly-N-acetyllactosamine metabolic process	6.688732e-3
GO:0048676	axon extension involved in development	6.698452e-3
GO:0050873	brown fat cell differentiation	6.699812e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	6.713499e-3
GO:0002115	store-operated calcium entry	6.713499e-3
GO:0051937	catecholamine transport	6.729126e-3
GO:0021514	ventral spinal cord interneuron differentiation	6.950944e-3
GO:0090201	negative regulation of release of cytochrome c from mitochondria	6.976440e-3
GO:0006303	double-strand break repair via nonhomologous end joining	6.976440e-3
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	7.058743e-3
GO:0002076	osteoblast development	7.088888e-3
GO:0042487	regulation of odontogenesis of dentine-containing tooth	7.177333e-3
GO:0003105	negative regulation of glomerular filtration	7.203547e-3
GO:0043320	natural killer cell degranulation	7.236779e-3
GO:0021558	trochlear nerve development	7.236779e-3
GO:0006836	neurotransmitter transport	7.266065e-3
GO:0043983	histone H4-K12 acetylation	7.358811e-3
GO:0060602	branch elongation of an epithelium	7.420618e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	7.510580e-3
GO:0022415	viral reproductive process	7.516724e-3
GO:0072060	outer medullary collecting duct development	7.557900e-3
GO:0072061	inner medullary collecting duct development	7.557900e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	7.557900e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	7.600713e-3
GO:0006401	RNA catabolic process	7.608025e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	7.638004e-3
GO:0006221	pyrimidine nucleotide biosynthetic process	7.680213e-3
GO:0045650	negative regulation of macrophage differentiation	7.853433e-3
GO:0021559	trigeminal nerve development	7.861912e-3
GO:0060535	trachea cartilage morphogenesis	8.093918e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	8.100058e-3
GO:0060242	contact inhibition	8.100058e-3
GO:0021533	cell differentiation in hindbrain	8.105529e-3
GO:0045618	positive regulation of keratinocyte differentiation	8.314318e-3
GO:0048818	positive regulation of hair follicle maturation	8.314318e-3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	8.314318e-3
GO:0070845	polyubiquitinated misfolded protein transport	8.387440e-3
GO:0009436	glyoxylate catabolic process	8.389402e-3
GO:0070170	regulation of tooth mineralization	8.459906e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	8.481756e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	8.679398e-3
GO:0001836	release of cytochrome c from mitochondria	8.699592e-3
GO:0006353	transcription termination, DNA-dependent	8.801539e-3
GO:0045066	regulatory T cell differentiation	8.820488e-3
GO:0060253	negative regulation of glial cell proliferation	8.992013e-3
GO:0061180	mammary gland epithelium development	8.996625e-3
GO:0070723	response to cholesterol	9.072373e-3
GO:0009265	2'-deoxyribonucleotide biosynthetic process	9.094924e-3
GO:0006390	transcription from mitochondrial promoter	9.246797e-3
GO:0010869	regulation of receptor biosynthetic process	9.295772e-3
GO:0002071	glandular epithelial cell maturation	9.342247e-3
GO:0000917	barrier septum formation	9.342247e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.466464e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	9.530652e-3
GO:0070194	synaptonemal complex disassembly	9.530652e-3
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	9.668510e-3
GO:0060923	cardiac muscle cell fate commitment	9.698747e-3
GO:0021678	third ventricle development	9.698747e-3
GO:0035313	wound healing, spreading of epidermal cells	9.709167e-3
GO:0034728	nucleosome organization	9.768247e-3
GO:0010821	regulation of mitochondrion organization	9.769275e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	9.784857e-3
GO:0060359	response to ammonium ion	9.792952e-3
GO:0050716	positive regulation of interleukin-1 secretion	9.855040e-3
GO:0000093	mitotic telophase	9.925068e-3
GO:0006402	mRNA catabolic process	9.962436e-3
GO:0005978	glycogen biosynthetic process	9.987531e-3
GO:0010452	histone H3-K36 methylation	1.006924e-2
GO:0000271	polysaccharide biosynthetic process	1.012127e-2
GO:0018022	peptidyl-lysine methylation	1.024238e-2
GO:0005993	trehalose catabolic process	1.037645e-2
GO:0016559	peroxisome fission	1.037645e-2
GO:0042273	ribosomal large subunit biogenesis	1.043942e-2
GO:0033032	regulation of myeloid cell apoptosis	1.067165e-2
GO:0033504	floor plate development	1.072030e-2
GO:0032095	regulation of response to food	1.072973e-2
GO:0020028	hemoglobin import	1.094037e-2
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	1.114401e-2
GO:0014719	satellite cell activation	1.114401e-2
GO:0051795	positive regulation of catagen	1.128677e-2
GO:0019227	neuronal action potential propagation	1.137168e-2
GO:0001561	fatty acid alpha-oxidation	1.140203e-2
GO:0045343	regulation of MHC class I biosynthetic process	1.151356e-2
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	1.152941e-2
GO:0033133	positive regulation of glucokinase activity	1.163294e-2
GO:0021575	hindbrain morphogenesis	1.165367e-2
GO:2001044	regulation of integrin-mediated signaling pathway	1.174481e-2
GO:0032474	otolith morphogenesis	1.174481e-2
GO:0006741	NADP biosynthetic process	1.174481e-2
GO:0021532	neural tube patterning	1.200423e-2
GO:0006333	chromatin assembly or disassembly	1.208699e-2
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	1.209366e-2
GO:0030318	melanocyte differentiation	1.213336e-2
GO:0009636	response to toxin	1.219456e-2
GO:0021571	rhombomere 5 development	1.247672e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0060923	cardiac muscle cell fate commitment	2.086099e-10
GO:0060911	cardiac cell fate commitment	1.313870e-8
GO:0090083	regulation of inclusion body assembly	2.052600e-8
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.248306e-8
GO:0060299	negative regulation of sarcomere organization	3.248306e-8
GO:0060932	His-Purkinje system cell differentiation	4.692870e-8
GO:0060926	pacemaker cell development	4.692870e-8
GO:0060920	pacemaker cell differentiation	9.010162e-8
GO:0010159	specification of organ position	1.539555e-7
GO:0045416	positive regulation of interleukin-8 biosynthetic process	1.066657e-6
GO:0090084	negative regulation of inclusion body assembly	1.101375e-6
GO:0003163	sinoatrial node development	1.358790e-6
GO:0003167	atrioventricular bundle cell differentiation	1.562217e-6
GO:0060931	sinoatrial node cell development	1.562217e-6
GO:0032094	response to food	1.690144e-6
GO:0006012	galactose metabolic process	1.722919e-6
GO:0060047	heart contraction	1.742472e-6
GO:0060921	sinoatrial node cell differentiation	2.723834e-6
GO:0005981	regulation of glycogen catabolic process	2.902760e-6
GO:0070842	aggresome assembly	4.094571e-6
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.205097e-6
GO:0003161	cardiac conduction system development	7.116796e-6
GO:0034260	negative regulation of GTPase activity	7.950292e-6
GO:0060048	cardiac muscle contraction	8.768935e-6
GO:0034421	post-translational protein acetylation	9.748536e-6
GO:0030382	sperm mitochondrion organization	1.041893e-5
GO:0003166	bundle of His development	1.476667e-5
GO:0021586	pons maturation	1.526136e-5
GO:0090231	regulation of spindle checkpoint	1.738287e-5
GO:0033005	positive regulation of mast cell activation	1.903001e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.089295e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.089295e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	2.089295e-5
GO:0032707	negative regulation of interleukin-23 production	2.089295e-5
GO:0032757	positive regulation of interleukin-8 production	2.154938e-5
GO:0043306	positive regulation of mast cell degranulation	2.426067e-5
GO:0034509	centromeric core chromatin assembly	2.432284e-5
GO:0034080	CenH3-containing nucleosome assembly at centromere	2.432284e-5
GO:0019285	glycine betaine biosynthetic process from choline	2.745192e-5
GO:0032275	luteinizing hormone secretion	3.743055e-5
GO:0046884	follicle-stimulating hormone secretion	3.743055e-5
GO:0003015	heart process	3.859303e-5
GO:0042339	keratan sulfate metabolic process	4.494210e-5
GO:0045414	regulation of interleukin-8 biosynthetic process	4.880225e-5
GO:0018364	peptidyl-glutamine methylation	5.095311e-5
GO:0032647	regulation of interferon-alpha production	5.645614e-5
GO:0032648	regulation of interferon-beta production	5.996517e-5
GO:0032218	riboflavin transport	6.042099e-5
GO:0043302	positive regulation of leukocyte degranulation	6.690968e-5
GO:0035802	adrenal cortex formation	6.700499e-5
GO:0045359	positive regulation of interferon-beta biosynthetic process	8.335831e-5
GO:0042398	cellular modified amino acid biosynthetic process	9.246972e-5
GO:0090086	negative regulation of protein deubiquitination	1.163433e-4
GO:2000491	positive regulation of hepatic stellate cell activation	1.304200e-4
GO:0021935	cerebellar granule cell precursor tangential migration	1.304200e-4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	1.308520e-4
GO:0051148	negative regulation of muscle cell differentiation	1.313793e-4
GO:0090192	regulation of glomerulus development	1.415679e-4
GO:0019255	glucose 1-phosphate metabolic process	1.608371e-4
GO:0033578	protein glycosylation in Golgi	1.631719e-4
GO:0045964	positive regulation of dopamine metabolic process	1.761115e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	1.803254e-4
GO:0080164	regulation of nitric oxide metabolic process	1.803254e-4
GO:0006825	copper ion transport	2.039550e-4
GO:0001880	Mullerian duct regression	2.186412e-4
GO:0045749	negative regulation of S phase of mitotic cell cycle	2.902402e-4
GO:0051586	positive regulation of dopamine uptake	2.979498e-4
GO:0060216	definitive hemopoiesis	3.281213e-4
GO:0051775	response to redox state	3.350617e-4
GO:0008355	olfactory learning	3.350617e-4
GO:0006409	tRNA export from nucleus	3.582389e-4
GO:0006427	histidyl-tRNA aminoacylation	3.582389e-4
GO:0031329	regulation of cellular catabolic process	3.610868e-4
GO:0007405	neuroblast proliferation	3.802538e-4
GO:0051150	regulation of smooth muscle cell differentiation	4.033242e-4
GO:0072298	regulation of metanephric glomerulus development	4.388178e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.524721e-4
GO:0006413	translational initiation	4.559308e-4
GO:0021998	neural plate mediolateral regionalization	4.574470e-4
GO:0048352	paraxial mesoderm structural organization	4.574470e-4
GO:0048672	positive regulation of collateral sprouting	4.980384e-4
GO:0032479	regulation of type I interferon production	5.182391e-4
GO:0006089	lactate metabolic process	5.186043e-4
GO:0032781	positive regulation of ATPase activity	5.267100e-4
GO:0033121	regulation of purine nucleotide catabolic process	5.996707e-4
GO:0072125	negative regulation of glomerular mesangial cell proliferation	6.395157e-4
GO:0045357	regulation of interferon-beta biosynthetic process	6.598751e-4
GO:0016559	peroxisome fission	6.671652e-4
GO:0016557	peroxisome membrane biogenesis	7.501122e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.869184e-4
GO:0006030	chitin metabolic process	8.074323e-4
GO:0002418	immune response to tumor cell	8.180551e-4
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	8.180551e-4
GO:0051103	DNA ligation involved in DNA repair	8.317026e-4
GO:0032849	positive regulation of cellular pH reduction	8.463357e-4
GO:2000426	negative regulation of apoptotic cell clearance	8.481007e-4
GO:0060821	inactivation of X chromosome by DNA methylation	8.636409e-4
GO:0072355	histone H3-T3 phosphorylation	8.636409e-4
GO:0006258	UDP-glucose catabolic process	8.636409e-4
GO:0016578	histone deubiquitination	9.099897e-4
GO:0035115	embryonic forelimb morphogenesis	9.155825e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	9.582277e-4
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1.011046e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	1.061562e-3
GO:0015670	carbon dioxide transport	1.075018e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1.077179e-3
GO:0048670	regulation of collateral sprouting	1.122847e-3
GO:2001076	positive regulation of metanephric ureteric bud development	1.123680e-3
GO:0007356	thorax and anterior abdomen determination	1.123680e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.123680e-3
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.188836e-3
GO:0035412	regulation of catenin import into nucleus	1.207048e-3
GO:0009081	branched chain family amino acid metabolic process	1.232963e-3
GO:0030539	male genitalia development	1.234763e-3
GO:0022904	respiratory electron transport chain	1.269853e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	1.344247e-3
GO:0007090	regulation of S phase of mitotic cell cycle	1.357354e-3
GO:0043407	negative regulation of MAP kinase activity	1.403621e-3
GO:0090287	regulation of cellular response to growth factor stimulus	1.413236e-3
GO:0043457	regulation of cellular respiration	1.429080e-3
GO:0021502	neural fold elevation formation	1.429080e-3
GO:0000212	meiotic spindle organization	1.429080e-3
GO:0032274	gonadotropin secretion	1.446784e-3
GO:0032727	positive regulation of interferon-alpha production	1.449304e-3
GO:0045662	negative regulation of myoblast differentiation	1.460525e-3
GO:0051386	regulation of nerve growth factor receptor signaling pathway	1.462917e-3
GO:0006658	phosphatidylserine metabolic process	1.462917e-3
GO:0006266	DNA ligation	1.462917e-3
GO:0035417	negative regulation of mitotic prometaphase	1.556272e-3
GO:0048382	mesendoderm development	1.631821e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	1.657360e-3
GO:0035887	aortic smooth muscle cell differentiation	1.809702e-3
GO:0051494	negative regulation of cytoskeleton organization	1.812346e-3
GO:0006659	phosphatidylserine biosynthetic process	1.818593e-3
GO:0035414	negative regulation of catenin import into nucleus	1.831113e-3
GO:0051639	actin filament network formation	1.846162e-3
GO:0007092	activation of mitotic anaphase-promoting complex activity	1.846162e-3
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	1.846162e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	1.890894e-3
GO:0031584	activation of phospholipase D activity	1.919332e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	1.947915e-3
GO:0002537	nitric oxide production involved in inflammatory response	2.008533e-3
GO:0032370	positive regulation of lipid transport	2.061128e-3
GO:0048671	negative regulation of collateral sprouting	2.089224e-3
GO:0043087	regulation of GTPase activity	2.117972e-3
GO:0002561	basophil degranulation	2.227656e-3
GO:0002357	defense response to tumor cell	2.227656e-3
GO:0071545	inositol phosphate catabolic process	2.240834e-3
GO:0001841	neural tube formation	2.262220e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	2.274689e-3
GO:0033124	regulation of GTP catabolic process	2.297836e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.305902e-3
GO:0072015	glomerular visceral epithelial cell development	2.305902e-3
GO:0051301	cell division	2.376688e-3
GO:0033006	regulation of mast cell activation involved in immune response	2.461752e-3
GO:0021535	cell migration in hindbrain	2.471840e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.487167e-3
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	2.633071e-3
GO:0010875	positive regulation of cholesterol efflux	2.762696e-3
GO:0033261	regulation of S phase	2.782538e-3
GO:0046599	regulation of centriole replication	2.820586e-3
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	3.034025e-3
GO:0046488	phosphatidylinositol metabolic process	3.069504e-3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3.117217e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	3.171848e-3
GO:0046755	non-lytic virus budding	3.171848e-3
GO:0006551	leucine metabolic process	3.179639e-3
GO:0002092	positive regulation of receptor internalization	3.225280e-3
GO:0032728	positive regulation of interferon-beta production	3.353132e-3
GO:0042254	ribosome biogenesis	3.376100e-3
GO:0043687	post-translational protein modification	3.523526e-3
GO:0051129	negative regulation of cellular component organization	3.749685e-3
GO:0051488	activation of anaphase-promoting complex activity	3.783785e-3
GO:0006578	betaine biosynthetic process	3.783785e-3
GO:0003197	endocardial cushion development	3.911470e-3
GO:0046855	inositol phosphate dephosphorylation	3.991549e-3
GO:0034470	ncRNA processing	4.036844e-3
GO:0017148	negative regulation of translation	4.049010e-3
GO:0016180	snRNA processing	4.120089e-3
GO:0033523	histone H2B ubiquitination	4.166035e-3
GO:2000425	regulation of apoptotic cell clearance	4.246861e-3
GO:0010948	negative regulation of cell cycle process	4.247908e-3
GO:0071529	cementum mineralization	4.289464e-3
GO:0090085	regulation of protein deubiquitination	4.289464e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	4.290344e-3
GO:0006561	proline biosynthetic process	4.290344e-3
GO:0007614	short-term memory	4.617966e-3
GO:0035117	embryonic arm morphogenesis	4.670463e-3
GO:0003156	regulation of organ formation	4.682851e-3
GO:0043471	regulation of cellular carbohydrate catabolic process	4.709068e-3
GO:0006288	base-excision repair, DNA ligation	4.714893e-3
GO:0006032	chitin catabolic process	4.714893e-3
GO:0009236	cobalamin biosynthetic process	4.720211e-3
GO:0022400	regulation of rhodopsin mediated signaling pathway	4.720211e-3
GO:0045575	basophil activation	4.720211e-3
GO:0019047	provirus integration	4.720211e-3
GO:0051147	regulation of muscle cell differentiation	4.741385e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	4.771797e-3
GO:0045661	regulation of myoblast differentiation	5.071648e-3
GO:0010874	regulation of cholesterol efflux	5.086449e-3
GO:0032776	DNA methylation on cytosine	5.149903e-3
GO:0043966	histone H3 acetylation	5.265681e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	5.275424e-3
GO:0050861	positive regulation of B cell receptor signaling pathway	5.275424e-3
GO:0043304	regulation of mast cell degranulation	5.423789e-3
GO:0048368	lateral mesoderm development	5.432376e-3
GO:0002318	myeloid progenitor cell differentiation	5.501464e-3
GO:0030046	parallel actin filament bundle assembly	5.506675e-3
GO:0015705	iodide transport	5.506675e-3
GO:0034661	ncRNA catabolic process	5.546901e-3
GO:0014020	primary neural tube formation	5.624161e-3
GO:0001947	heart looping	5.644070e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	5.676743e-3
GO:0016925	protein sumoylation	5.778012e-3
GO:0045819	positive regulation of glycogen catabolic process	5.780129e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	5.881998e-3
GO:0046434	organophosphate catabolic process	5.884415e-3
GO:0034261	negative regulation of Ras GTPase activity	6.199279e-3
GO:0032376	positive regulation of cholesterol transport	6.228449e-3
GO:0050850	positive regulation of calcium-mediated signaling	6.318746e-3
GO:0052556	positive regulation by symbiont of host immune response	6.407448e-3
GO:0003285	septum secundum development	6.407448e-3
GO:0052509	positive regulation by symbiont of host defense response	6.407448e-3
GO:0030902	hindbrain development	6.431133e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	6.448480e-3
GO:0021783	preganglionic parasympathetic nervous system development	6.718224e-3
GO:0060179	male mating behavior	6.893674e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	6.893674e-3
GO:0006097	glyoxylate cycle	6.893674e-3
GO:0001560	regulation of cell growth by extracellular stimulus	6.974225e-3
GO:0043482	cellular pigment accumulation	7.025789e-3
GO:0022037	metencephalon development	7.158845e-3
GO:0042274	ribosomal small subunit biogenesis	7.346811e-3
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	7.379224e-3
GO:0010587	miRNA catabolic process	7.379224e-3
GO:0051541	elastin metabolic process	7.410599e-3
GO:2000297	negative regulation of synapse maturation	7.448763e-3
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	7.448763e-3
GO:0042048	olfactory behavior	7.448763e-3
GO:0009169	purine ribonucleoside monophosphate catabolic process	7.448763e-3
GO:0048532	anatomical structure arrangement	7.565326e-3
GO:0001759	organ induction	7.565326e-3
GO:0070244	negative regulation of thymocyte apoptosis	7.609832e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	7.610929e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	7.885005e-3
GO:0032264	IMP salvage	8.187269e-3
GO:0046038	GMP catabolic process	8.187269e-3
GO:0023035	CD40 signaling pathway	8.187269e-3
GO:0006178	guanine salvage	8.187269e-3
GO:0032263	GMP salvage	8.187269e-3
GO:0043576	regulation of respiratory gaseous exchange	8.232761e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	8.462527e-3
GO:0060155	platelet dense granule organization	8.471328e-3
GO:0060928	atrioventricular node cell development	8.576781e-3
GO:0060929	atrioventricular node cell fate commitment	8.576781e-3
GO:0006844	acyl carnitine transport	8.576781e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	8.576781e-3
GO:0002462	tolerance induction to nonself antigen	8.576781e-3
GO:0003342	proepicardium development	8.576781e-3
GO:0061136	regulation of proteasomal protein catabolic process	8.717617e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	8.723083e-3
GO:0000422	mitochondrion degradation	8.723083e-3
GO:0060159	regulation of dopamine receptor signaling pathway	8.778265e-3
GO:0043388	positive regulation of DNA binding	9.071650e-3
GO:0001838	embryonic epithelial tube formation	9.094023e-3
GO:0000085	G2 phase of mitotic cell cycle	9.611307e-3
GO:0072198	mesenchymal cell proliferation involved in ureter development	9.622464e-3
GO:0072192	ureter epithelial cell differentiation	9.622464e-3
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	9.622464e-3
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	9.622464e-3
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	9.622464e-3
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	9.622464e-3
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	9.622464e-3
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	9.622464e-3
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	9.622464e-3
GO:0090194	negative regulation of glomerulus development	9.622464e-3
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	9.622464e-3
GO:0007500	mesodermal cell fate determination	9.622464e-3
GO:0055020	positive regulation of cardiac muscle fiber development	9.622464e-3
GO:0071893	BMP signaling pathway involved in nephric duct formation	9.622464e-3
GO:0048392	intermediate mesodermal cell differentiation	9.622464e-3
GO:0006481	C-terminal protein methylation	9.622464e-3
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	9.622464e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	9.622464e-3
GO:0061155	pulmonary artery endothelial tube morphogenesis	9.622464e-3
GO:0061151	BMP signaling pathway involved in renal system segmentation	9.622464e-3
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	9.622464e-3
GO:0060503	bud dilation involved in lung branching	9.622464e-3
GO:0051153	regulation of striated muscle cell differentiation	9.661225e-3
GO:0031128	developmental induction	9.764634e-3
GO:0035928	rRNA import into mitochondrion	9.848843e-3
GO:0019388	galactose catabolic process	9.848843e-3
GO:0009268	response to pH	9.863759e-3
GO:0045454	cell redox homeostasis	1.000354e-2
GO:0060396	growth hormone receptor signaling pathway	1.003247e-2
GO:0032785	negative regulation of transcription elongation, DNA-dependent	1.008302e-2
GO:0033205	cell cycle cytokinesis	1.008448e-2
GO:0007252	I-kappaB phosphorylation	1.017909e-2
GO:0001675	acrosome assembly	1.017909e-2
GO:0032025	response to cobalt ion	1.030857e-2
GO:0003350	pulmonary myocardium development	1.030857e-2
GO:0060449	bud elongation involved in lung branching	1.038408e-2
GO:0033363	secretory granule organization	1.073903e-2
GO:0010741	negative regulation of intracellular protein kinase cascade	1.110521e-2
GO:0046856	phosphatidylinositol dephosphorylation	1.112479e-2
GO:0072215	regulation of metanephros development	1.123407e-2
GO:0000266	mitochondrial fission	1.141802e-2
GO:0002224	toll-like receptor signaling pathway	1.141802e-2
GO:0016073	snRNA metabolic process	1.144346e-2
GO:0006941	striated muscle contraction	1.159527e-2
GO:0016358	dendrite development	1.163538e-2
GO:0048486	parasympathetic nervous system development	1.165010e-2
GO:0002221	pattern recognition receptor signaling pathway	1.181578e-2
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.204225e-2
GO:0071711	basement membrane organization	1.204225e-2
GO:0090238	positive regulation of arachidonic acid secretion	1.204898e-2
GO:0045356	positive regulation of interferon-alpha biosynthetic process	1.204898e-2
GO:0018095	protein polyglutamylation	1.204898e-2
GO:0002138	retinoic acid biosynthetic process	1.204898e-2
GO:0071378	cellular response to growth hormone stimulus	1.205930e-2
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	1.210318e-2
GO:0021602	cranial nerve morphogenesis	1.214799e-2
GO:0061113	pancreas morphogenesis	1.217969e-2
GO:0033148	positive regulation of estrogen receptor signaling pathway	1.217969e-2
GO:0034660	ncRNA metabolic process	1.218415e-2
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.248513e-2
GO:0072175	epithelial tube formation	1.262439e-2
GO:0046129	purine ribonucleoside biosynthetic process	1.267591e-2
GO:0060427	lung connective tissue development	1.276662e-2
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.298320e-2
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.298320e-2
GO:0034394	protein localization at cell surface	1.299924e-2
GO:2000171	negative regulation of dendrite development	1.319090e-2
GO:0090340	positive regulation of secretion of lysosomal enzymes	1.343029e-2
GO:0090187	positive regulation of pancreatic juice secretion	1.343029e-2
GO:0006393	termination of mitochondrial transcription	1.343029e-2
GO:0060847	endothelial cell fate specification	1.343029e-2
GO:0090108	positive regulation of high-density lipoprotein particle assembly	1.343029e-2
GO:2000018	regulation of male gonad development	1.354484e-2
GO:0031331	positive regulation of cellular catabolic process	1.384928e-2
GO:0070734	histone H3-K27 methylation	1.391012e-2
GO:0061156	pulmonary artery morphogenesis	1.391012e-2
GO:0030836	positive regulation of actin filament depolymerization	1.391012e-2
GO:0051001	negative regulation of nitric-oxide synthase activity	1.398479e-2
GO:0042417	dopamine metabolic process	1.400340e-2
GO:0071882	activation of phospholipase C activity by adrenergic receptor signaling pathway	1.403234e-2
GO:0071881	inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway	1.403234e-2
GO:0016331	morphogenesis of embryonic epithelium	1.415577e-2
GO:0006346	methylation-dependent chromatin silencing	1.420388e-2
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	1.420388e-2
GO:0016082	synaptic vesicle priming	1.420842e-2
GO:0006546	glycine catabolic process	1.420842e-2
GO:0042773	ATP synthesis coupled electron transport	1.425077e-2
GO:0060390	regulation of SMAD protein import into nucleus	1.455933e-2
GO:0060729	intestinal epithelial structure maintenance	1.479598e-2
GO:0002282	microglial cell activation involved in immune response	1.479598e-2
GO:0009894	regulation of catabolic process	1.503698e-2
GO:0048285	organelle fission	1.510390e-2
GO:0016072	rRNA metabolic process	1.532057e-2
GO:0010639	negative regulation of organelle organization	1.536475e-2
GO:0060754	positive regulation of mast cell chemotaxis	1.555061e-2
GO:0001661	conditioned taste aversion	1.555061e-2
GO:0014819	regulation of skeletal muscle contraction	1.558343e-2
GO:0071354	cellular response to interleukin-6	1.583549e-2
GO:0060033	anatomical structure regression	1.595945e-2
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.596079e-2
GO:0032364	oxygen homeostasis	1.605003e-2
GO:0021756	striatum development	1.606698e-2
GO:0046847	filopodium assembly	1.611192e-2
GO:0043586	tongue development	1.617860e-2
GO:0045768	positive regulation of anti-apoptosis	1.622998e-2
GO:0016539	intein-mediated protein splicing	1.625685e-2
GO:0045654	positive regulation of megakaryocyte differentiation	1.653269e-2
GO:0006166	purine ribonucleoside salvage	1.653269e-2
GO:0006072	glycerol-3-phosphate metabolic process	1.665566e-2
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.666108e-2
GO:0021915	neural tube development	1.670771e-2
GO:0050918	positive chemotaxis	1.681143e-2
GO:0000724	double-strand break repair via homologous recombination	1.681143e-2
GO:0070831	basement membrane assembly	1.698072e-2
GO:0045226	extracellular polysaccharide biosynthetic process	1.698072e-2
GO:0046500	S-adenosylmethionine metabolic process	1.699811e-2
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.699873e-2
GO:0014743	regulation of muscle hypertrophy	1.707384e-2
GO:0003283	atrial septum development	1.707384e-2
GO:0045123	cellular extravasation	1.709617e-2
GO:0035990	tendon cell differentiation	1.722454e-2
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.722454e-2
GO:0045862	positive regulation of proteolysis	1.725317e-2
GO:0051297	centrosome organization	1.747684e-2
GO:0060828	regulation of canonical Wnt receptor signaling pathway	1.755879e-2
GO:0043409	negative regulation of MAPKKK cascade	1.762763e-2
GO:0006661	phosphatidylinositol biosynthetic process	1.809097e-2
GO:0072166	posterior mesonephric tubule development	1.817391e-2
GO:0019344	cysteine biosynthetic process	1.817391e-2
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	1.841063e-2
GO:0050765	negative regulation of phagocytosis	1.896164e-2
GO:2000020	positive regulation of male gonad development	1.904222e-2
GO:0033373	maintenance of protease location in mast cell secretory granule	1.916135e-2
GO:0033382	maintenance of granzyme B location in T cell secretory granule	1.916135e-2
GO:0032225	regulation of synaptic transmission, dopaminergic	1.937955e-2
GO:0032486	Rap protein signal transduction	1.940419e-2
GO:0052572	response to host immune response	1.950360e-2
GO:0060413	atrial septum morphogenesis	2.020291e-2
GO:0030834	regulation of actin filament depolymerization	2.032841e-2
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	2.037134e-2
GO:0007049	cell cycle	2.047905e-2
GO:0001843	neural tube closure	2.087273e-2
GO:0021559	trigeminal nerve development	2.109454e-2
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	2.126749e-2
GO:0030327	prenylated protein catabolic process	2.126749e-2
GO:0008295	spermidine biosynthetic process	2.126749e-2
GO:0014063	negative regulation of serotonin secretion	2.126749e-2
GO:0030035	microspike assembly	2.128316e-2
GO:0045637	regulation of myeloid cell differentiation	2.140424e-2
GO:0030433	ER-associated protein catabolic process	2.157825e-2
GO:0048742	regulation of skeletal muscle fiber development	2.166303e-2
GO:0010811	positive regulation of cell-substrate adhesion	2.168476e-2
GO:0071843	cellular component biogenesis at cellular level	2.168854e-2
GO:0032481	positive regulation of type I interferon production	2.170444e-2
GO:0032677	regulation of interleukin-8 production	2.172550e-2
GO:2000104	negative regulation of DNA-dependent DNA replication	2.181828e-2
GO:0010832	negative regulation of myotube differentiation	2.181828e-2
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2.185664e-2
GO:0031055	chromatin remodeling at centromere	2.206946e-2
GO:0003151	outflow tract morphogenesis	2.214765e-2
GO:0006412	translation	2.216217e-2
GO:0043103	hypoxanthine salvage	2.224515e-2
GO:0060540	diaphragm morphogenesis	2.224515e-2
GO:0060464	lung lobe formation	2.224515e-2
GO:0032261	purine nucleotide salvage	2.224515e-2
GO:0018065	protein-cofactor linkage	2.224515e-2
GO:0006168	adenine salvage	2.224515e-2
GO:0031648	protein destabilization	2.243352e-2
GO:0051584	regulation of dopamine uptake	2.247382e-2
GO:0043101	purine-containing compound salvage	2.247382e-2
GO:0010830	regulation of myotube differentiation	2.266381e-2
GO:0035993	deltoid tuberosity development	2.278589e-2
GO:0016075	rRNA catabolic process	2.278589e-2
GO:0010572	positive regulation of platelet activation	2.278589e-2
GO:0060562	epithelial tube morphogenesis	2.300665e-2
GO:0007019	microtubule depolymerization	2.308518e-2
GO:0003278	apoptosis involved in heart morphogenesis	2.308518e-2
GO:0010575	positive regulation vascular endothelial growth factor production	2.314243e-2
GO:0048588	developmental cell growth	2.316251e-2
GO:0061004	pattern specification involved in kidney development	2.340536e-2
GO:0051891	positive regulation of cardioblast differentiation	2.360157e-2
GO:0043587	tongue morphogenesis	2.360157e-2
GO:0060691	epithelial cell maturation involved in salivary gland development	2.373874e-2
GO:0071284	cellular response to lead ion	2.373874e-2
GO:0060096	serotonin secretion, neurotransmission	2.373874e-2
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	2.373874e-2
GO:0018160	peptidyl-pyrromethane cofactor linkage	2.373874e-2
GO:0006571	tyrosine biosynthetic process	2.373874e-2
GO:0021545	cranial nerve development	2.376976e-2
GO:0018027	peptidyl-lysine dimethylation	2.381592e-2
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.381592e-2
GO:0030853	negative regulation of granulocyte differentiation	2.411539e-2
GO:0003382	epithelial cell morphogenesis	2.426062e-2
GO:0060986	endocrine hormone secretion	2.435292e-2
GO:0019695	choline metabolic process	2.466306e-2
GO:0009083	branched chain family amino acid catabolic process	2.466306e-2
GO:2001054	negative regulation of mesenchymal cell apoptosis	2.492607e-2
GO:0031054	pre-miRNA processing	2.504679e-2
GO:0046498	S-adenosylhomocysteine metabolic process	2.504679e-2
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.507001e-2
GO:0000725	recombinational repair	2.517961e-2
GO:0071526	semaphorin-plexin signaling pathway	2.535516e-2
GO:0043088	regulation of Cdc42 GTPase activity	2.563424e-2
GO:0043486	histone exchange	2.588374e-2
GO:0008595	anterior/posterior axis specification, embryo	2.595052e-2
GO:0035050	embryonic heart tube development	2.629498e-2
GO:0035162	embryonic hemopoiesis	2.649128e-2
GO:0072278	metanephric comma-shaped body morphogenesis	2.651825e-2
GO:0072284	metanephric S-shaped body morphogenesis	2.651825e-2
GO:0055099	response to high density lipoprotein particle stimulus	2.651825e-2
GO:0035022	positive regulation of Rac protein signal transduction	2.658495e-2
GO:0006596	polyamine biosynthetic process	2.658495e-2
GO:0070542	response to fatty acid	2.663489e-2
GO:0071223	cellular response to lipoteichoic acid	2.675717e-2
GO:0070925	organelle assembly	2.675967e-2
GO:0006556	S-adenosylmethionine biosynthetic process	2.687455e-2
GO:0042255	ribosome assembly	2.740572e-2
GO:0000188	inactivation of MAPK activity	2.746749e-2
GO:0010810	regulation of cell-substrate adhesion	2.781294e-2
GO:0042659	regulation of cell fate specification	2.814109e-2
GO:0021516	dorsal spinal cord development	2.814109e-2
GO:0046487	glyoxylate metabolic process	2.816371e-2
GO:0042245	RNA repair	2.816371e-2
GO:0008306	associative learning	2.816491e-2
GO:0021549	cerebellum development	2.837237e-2
GO:0010611	regulation of cardiac muscle hypertrophy	2.853217e-2
GO:0060606	tube closure	2.899657e-2
GO:2000602	regulation of interphase of mitotic cell cycle	2.931398e-2
GO:0045109	intermediate filament organization	2.951452e-2
GO:0045956	positive regulation of calcium ion-dependent exocytosis	2.962140e-2
GO:0045815	positive regulation of gene expression, epigenetic	2.962140e-2
GO:0009948	anterior/posterior axis specification	2.970388e-2
GO:0031442	positive regulation of mRNA 3'-end processing	2.978291e-2
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	2.990207e-2