CL:0000771: Difference between revisions
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|id=CL:0000771 | |id=CL:0000771 | ||
|name=eosinophil | |name=eosinophil | ||
|namespace=efo | |namespace=cell;;efo | ||
|def="Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] | |def="Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] | ||
|xref=BTO:0000399;;FMA:62861 | |xref=BTO:0000399;;FMA:62861 | ||
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|obo_creation_date= | |obo_creation_date= | ||
|subset= | |subset= | ||
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|develops_from= | |develops_from= | ||
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|located_in= | |located_in= | ||
|part_of= | |part_of= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | ||
|is_obsolete= | |is_obsolete= | ||
|preceded_by= | |preceded_by= | ||
}} | }} | ||
Revision as of 17:26, 26 June 2012
| Name: | eosinophil | ||
|---|---|---|---|
| Namespace: | cell;;efo | ||
| Definition: | "Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] | ||
| Xrefs: |
| ||
| Synonyms: |
"eosinocyte" EXACT [] "eosinophilic granulocyte" EXACT [] "eosinophilic leucocyte" EXACT [] "eosinophilic leukocyte" EXACT [] "polymorphonuclear leucocyte" BROAD [] "polymorphonuclear leukocyte" BROAD [] | ||
| Comments: | Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000094(granulocyte) |
|---|
Children
| derives from: | FF:0000054 (human eosinophil sample) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 11546-120B7
- 11626-122B6
- 11707-123B6
- 12244-129H3 (Eosinophils, donor1)
- 12245-129H4 (Eosinophils, donor2)
- 12246-129H5 (Eosinophils, donor3)
Mouse (Mus musculus)
- 11546-120B7
- 11626-122B6
- 11707-123B6
- 12244-129H3 (Eosinophils, donor1)
- 12245-129H4 (Eosinophils, donor2)
- 12246-129H5 (Eosinophils, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000771 (eosinophil), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 3.29e-195 | FFCP PHASE1:Hg19::chr20:58583854..58583859,+#_54590defd6044dd13ceebdd2a61e1ecf | p@chr20:58583854..58583859, + |
| 3.29e-195 | FFCP PHASE2:Hg19::chr20:58583854..58583859,+#_54590defd6044dd13ceebdd2a61e1ecf | p@chr20:58583854..58583859, + |
| 8.99e-131 | FFCP PHASE2:Hg19::chr12:78398581..78398586,-#_cf17571beecb4a14331c919d98545880 | p@chr12:78398581..78398586, - |
| 8.99e-131 | FFCP PHASE2:Hg19::chr6:2523125..2523129,+#_cf17571beecb4a14331c919d98545880 | p@chr6:2523125..2523129, + |
| 8.99e-131 | FFCP PHASE1:Hg19::chr12:78398581..78398586,-#_cf17571beecb4a14331c919d98545880 | p@chr12:78398581..78398586, - |
| 8.99e-131 | FFCP PHASE1:Hg19::chr17:7254317..7254321,+#_cf17571beecb4a14331c919d98545880 | p@chr17:7254317..7254321, + |
| 8.99e-131 | FFCP PHASE2:Hg19::chr17:7254317..7254321,+#_cf17571beecb4a14331c919d98545880 | p@chr17:7254317..7254321, + |
| 8.99e-131 | FFCP PHASE1:Hg19::chr6:2523125..2523129,+#_cf17571beecb4a14331c919d98545880 | p@chr6:2523125..2523129, + |
| 1.75e-130 | FFCP PHASE2:Hg19::chr1:94181180..94181200,-#_98efd0bb17207eee7587d867b161066c | p@chr1:94181180..94181200, - |
| 1.75e-130 | FFCP PHASE1:Hg19::chr1:94181180..94181200,-#_98efd0bb17207eee7587d867b161066c | p@chr1:94181180..94181200, - |
| 1.75e-130 | FFCP PHASE2:Hg19::chr20:61317566..61317586,-#_98efd0bb17207eee7587d867b161066c | p@chr20:61317566..61317586, - |
| 1.75e-130 | FFCP PHASE1:Hg19::chr20:61317566..61317586,-#_98efd0bb17207eee7587d867b161066c | p@chr20:61317566..61317586, - |
| 5.68e-99 | FFCP PHASE2:Hg19::chr11:325899..325904,-#_3067e9586a01faeaa652da522b258007 | p@chr11:325899..325904, - |
| 5.68e-99 | FFCP PHASE2:Hg19::chr12:66562929..66562938,-#_3067e9586a01faeaa652da522b258007 | p12@TMBIM4 |
| 5.68e-99 | FFCP PHASE1:Hg19::chr12:66562929..66562938,-#_3067e9586a01faeaa652da522b258007 | p12@TMBIM4 |
| 5.68e-99 | FFCP PHASE1:Hg19::chr2:70205032..70205037,+#_3067e9586a01faeaa652da522b258007 | p@chr2:70205032..70205037, + |
| 5.68e-99 | FFCP PHASE2:Hg19::chr2:70205032..70205037,+#_3067e9586a01faeaa652da522b258007 | p@chr2:70205032..70205037, + |
| 5.68e-99 | FFCP PHASE1:Hg19::chr11:325899..325904,-#_3067e9586a01faeaa652da522b258007 | p@chr11:325899..325904, - |
| 9.38e-99 | FFCP PHASE2:Hg19::chr10:6437802..6437809,+#_93917df58d355404d75d7d847647c8e4 | p@chr10:6437802..6437809, + |
| 9.38e-99 | FFCP PHASE2:Hg19::chr12:106697974..106697990,-#_93917df58d355404d75d7d847647c8e4 | p31@CKAP4 |
| 9.38e-99 | FFCP PHASE1:Hg19::chr12:106697974..106697990,-#_93917df58d355404d75d7d847647c8e4 | p31@CKAP4 |
| 9.38e-99 | FFCP PHASE1:Hg19::chr10:6437802..6437809,+#_93917df58d355404d75d7d847647c8e4 | p@chr10:6437802..6437809, + |
| 9.38e-99 | FFCP PHASE2:Hg19::chr1:36825695..36825702,+#_93917df58d355404d75d7d847647c8e4 | p@chr1:36825695..36825702, + |
| 9.38e-99 | FFCP PHASE1:Hg19::chr2:70246173..70246174,-#_93917df58d355404d75d7d847647c8e4 | p@chr2:70246173..70246174, - |
| 9.38e-99 | FFCP PHASE1:Hg19::chr1:36825695..36825702,+#_93917df58d355404d75d7d847647c8e4 | p@chr1:36825695..36825702, + |
| 9.38e-99 | FFCP PHASE2:Hg19::chr2:70246173..70246174,-#_93917df58d355404d75d7d847647c8e4 | p@chr2:70246173..70246174, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr19:21860925..21860945,-#_31496fd395bf59391fdb1b33884fc25d | p@chr19:21860925..21860945, - |
| 1.55e-98 | FFCP PHASE2:Hg19::chr14:62035649..62035652,+#_31496fd395bf59391fdb1b33884fc25d | p@chr14:62035649..62035652, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr19:21860925..21860945,-#_31496fd395bf59391fdb1b33884fc25d | p@chr19:21860925..21860945, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr5:126147844..126147847,+#_31496fd395bf59391fdb1b33884fc25d | p@chr5:126147844..126147847, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr5:126147844..126147847,+#_31496fd395bf59391fdb1b33884fc25d | p@chr5:126147844..126147847, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr10:125797517..125797522,-#_31496fd395bf59391fdb1b33884fc25d | p@chr10:125797517..125797522, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr14:62035649..62035652,+#_31496fd395bf59391fdb1b33884fc25d | p@chr14:62035649..62035652, + |
| 1.55e-98 | FFCP PHASE1:Hg19::chr17:7835843..7835845,-#_31496fd395bf59391fdb1b33884fc25d | p@chr17:7835843..7835845, - |
| 1.55e-98 | FFCP PHASE2:Hg19::chr17:7835843..7835845,-#_31496fd395bf59391fdb1b33884fc25d | p@chr17:7835843..7835845, - |
| 1.55e-98 | FFCP PHASE1:Hg19::chr10:125797517..125797522,-#_31496fd395bf59391fdb1b33884fc25d | p@chr10:125797517..125797522, - |
| 1.55e-98 | FFCP PHASE2:Hg19::chr12:132345733..132345736,+#_31496fd395bf59391fdb1b33884fc25d | p@chr12:132345733..132345736, + |
| 1.55e-98 | FFCP PHASE1:Hg19::chr12:132345733..132345736,+#_31496fd395bf59391fdb1b33884fc25d | p@chr12:132345733..132345736, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr8:6875818..6875822,-#_31496fd395bf59391fdb1b33884fc25d | p1@DEFA1B, p1@DEFA1, p1@DEFA3 |
| 1.55e-98 | FFCP PHASE1:Hg19::chr8:6875818..6875822,-#_31496fd395bf59391fdb1b33884fc25d | p1@DEFA1B, p1@DEFA1, p1@DEFA3 |
| 2.56e-98 | FFCP PHASE2:Hg19::chr10:129052667..129052672,-#_acf1cfc773444e45495387ec9e7ebd59 | p@chr10:129052667..129052672, - |
| 2.56e-98 | FFCP PHASE1:Hg19::chr10:129052667..129052672,-#_acf1cfc773444e45495387ec9e7ebd59 | p@chr10:129052667..129052672, - |
| 2.56e-98 | FFCP PHASE2:Hg19::chr1:28453609..28453619,+#_acf1cfc773444e45495387ec9e7ebd59 | p@chr1:28453609..28453619, + |
| 2.56e-98 | FFCP PHASE1:Hg19::chr1:28453609..28453619,+#_acf1cfc773444e45495387ec9e7ebd59 | p@chr1:28453609..28453619, + |
| 2.56e-98 | FFCP PHASE2:Hg19::chr1:208712314..208712317,+#_acf1cfc773444e45495387ec9e7ebd59 | p@chr1:208712314..208712317, + |
| 2.56e-98 | FFCP PHASE1:Hg19::chr1:208712314..208712317,+#_acf1cfc773444e45495387ec9e7ebd59 | p@chr1:208712314..208712317, + |
| 2.56e-98 | FFCP PHASE2:Hg19::chr19:47885192..47885197,-#_acf1cfc773444e45495387ec9e7ebd59 | p@chr19:47885192..47885197, - |
| 2.56e-98 | FFCP PHASE1:Hg19::chr19:47885192..47885197,-#_acf1cfc773444e45495387ec9e7ebd59 | p@chr19:47885192..47885197, - |
| 1.05e-79 | FFCP PHASE2:Hg19::chr9:129233326..129233330,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr9:129233326..129233330, - |
| 1.05e-79 | FFCP PHASE2:Hg19::chr11:1865720..1865724,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr11:1865720..1865724, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr1:235099440..235099448,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:235099440..235099448, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr1:182367189..182367199,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:182367189..182367199, + |
| 1.05e-79 | FFCP PHASE1:Hg19::chr1:235099440..235099448,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:235099440..235099448, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr4:74581933..74581937,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr4:74581933..74581937, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr8:133774199..133774210,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr8:133774199..133774210, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr4:74581933..74581937,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr4:74581933..74581937, + |
| 1.05e-79 | FFCP PHASE1:Hg19::chr8:133774199..133774210,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr8:133774199..133774210, - |
| 1.05e-79 | FFCP PHASE2:Hg19::chr5:142384316..142384325,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr5:142384316..142384325, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr1:185389704..185389711,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:185389704..185389711, + |
| 1.05e-79 | FFCP PHASE1:Hg19::chr5:142384316..142384325,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr5:142384316..142384325, - |
| 1.05e-79 | FFCP PHASE2:Hg19::chr15:75370087..75370094,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr15:75370087..75370094, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr17:34617878..34617880,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr17:34617878..34617880, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr15:90579320..90579331,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr15:90579320..90579331, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr1:182367189..182367199,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:182367189..182367199, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr17:34617878..34617880,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr17:34617878..34617880, - |
| 1.05e-79 | FFCP PHASE2:Hg19::chr1:185389704..185389711,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr1:185389704..185389711, + |
| 1.05e-79 | FFCP PHASE1:Hg19::chr11:1865720..1865724,+#_3e70302a07f2e1fbba9b582277365dc6 | p@chr11:1865720..1865724, + |
| 1.05e-79 | FFCP PHASE2:Hg19::chr15:90579320..90579331,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr15:90579320..90579331, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr15:75370087..75370094,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr15:75370087..75370094, - |
| 1.05e-79 | FFCP PHASE1:Hg19::chr9:129233326..129233330,-#_3e70302a07f2e1fbba9b582277365dc6 | p@chr9:129233326..129233330, - |
| 1.56e-79 | FFCP PHASE1:Hg19::chr1:198571112..198571115,-#_d2cf605625a135a61524fbd83f9f30ac | p@chr1:198571112..198571115, - |
| 1.56e-79 | FFCP PHASE1:Hg19::chr2:68613090..68613098,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr2:68613090..68613098, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr15:101662027..101662033,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr15:101662027..101662033, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr15:89672367..89672372,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr15:89672367..89672372, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr1:206731759..206731770,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr1:206731759..206731770, + |
| 1.56e-79 | FFCP PHASE1:Hg19::chr1:206731759..206731770,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr1:206731759..206731770, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr1:198571112..198571115,-#_d2cf605625a135a61524fbd83f9f30ac | p@chr1:198571112..198571115, - |
| 1.56e-79 | FFCP PHASE2:Hg19::chr2:68613090..68613098,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr2:68613090..68613098, + |
| 1.56e-79 | FFCP PHASE1:Hg19::chr15:101662027..101662033,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr15:101662027..101662033, + |
| 1.56e-79 | FFCP PHASE1:Hg19::chr11:15647581..15647597,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr11:15647581..15647597, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr11:15647581..15647597,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr11:15647581..15647597, + |
| 1.56e-79 | FFCP PHASE2:Hg19::chr7:128048285..128048310,-#_d2cf605625a135a61524fbd83f9f30ac | p@chr7:128048285..128048310, - |
| 1.56e-79 | FFCP PHASE1:Hg19::chr7:128048285..128048310,-#_d2cf605625a135a61524fbd83f9f30ac | p@chr7:128048285..128048310, - |
| 1.56e-79 | FFCP PHASE1:Hg19::chr15:89672367..89672372,+#_d2cf605625a135a61524fbd83f9f30ac | p@chr15:89672367..89672372, + |
| 2.34e-79 | FFCP PHASE2:Hg19::chr2:120967889..120967892,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:120967889..120967892, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr2:120967889..120967892,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:120967889..120967892, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr2:70246139..70246146,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:70246139..70246146, - |
| 2.34e-79 | FFCP PHASE2:Hg19::chr2:103106370..103106380,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:103106370..103106380, + |
| 2.34e-79 | FFCP PHASE1:Hg19::chr2:103106370..103106380,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:103106370..103106380, + |
| 2.34e-79 | FFCP PHASE2:Hg19::chr2:70246139..70246146,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:70246139..70246146, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr2:28823344..28823354,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:28823344..28823354, + |
| 2.34e-79 | FFCP PHASE2:Hg19::chr22:43288684..43288705,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr22:43288684..43288705, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr22:43288684..43288705,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr22:43288684..43288705, - |
| 2.34e-79 | FFCP PHASE2:Hg19::chr7:75268487..75268499,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr7:75268487..75268499, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr7:75268487..75268499,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr7:75268487..75268499, - |
| 2.34e-79 | FFCP PHASE2:Hg19::chr1:208712347..208712354,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr1:208712347..208712354, + |
| 2.34e-79 | FFCP PHASE2:Hg19::chr2:28823344..28823354,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr2:28823344..28823354, + |
| 2.34e-79 | FFCP PHASE1:Hg19::chr1:208712347..208712354,+#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr1:208712347..208712354, + |
| 2.34e-79 | FFCP PHASE2:Hg19::chr9:140501563..140501569,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr9:140501563..140501569, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr9:140501563..140501569,-#_4cf74f1f3726f3f3669a9e6ec51495ab | p@chr9:140501563..140501569, - |
