UBERON:0003126: Difference between revisions
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|subset=major_organ;;uberon_slim | |subset=major_organ;;uberon_slim | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from=UBERON:0008947 | ||
|has_quality= | |has_quality= | ||
|located_in= | |located_in= | ||
|part_of= | |part_of=UBERON:0002224;;UBERON:0007196 | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "An elongated tube which carries air to and from the lungs.[AAO]" xsd:string | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "An elongated tube which carries air to and from the lungs.[AAO]" xsd:string | ||
|is_obsolete= | |is_obsolete= | ||
|preceded_by= | |preceded_by= | ||
}} | }} |
Revision as of 13:33, 27 June 2012
Name: | trachea | ||
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Definition: | "A trachea held open by up to 20 C-shaped rings of cartilage [Wikipedia]. The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." [GO:0060438, Wikipedia:Vertebrate_trachea] | ||
Xrefs: |
| ||
Synonyms: |
"cartilaginous trachea" EXACT [] "tracheal tubule" RELATED [BTO:0001388] "vertebrate trachea" EXACT SENSU [] "windpipe" EXACT [] | ||
Comments: | In birds, the trachea runs from the pharynx to the syrinx, from which the primary bronchi diverge. Swans have an unusually elongated trachea, part of which is coiled beneath the sternum; this may act as a resonator to amplify sound. In some birds, the cartilagenous rings are complete, and may even be ossified. In amphibians, the trachea is normally extremely short, and leads directly into the lungs, without clear primary bronchi. A longer trachea is, however found in some long-necked salamanders, and in caecilians. While there are irregular cartilagenous nodules on the amphibian trachea, these do not form the rings found in amniotes. The only vertebrate to have lungs, but no trachea, is Polypterus, in which the lungs arise directly from the pharynx. | ||
Subset: |
major_organ uberon_slim |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0001005(respiratory airway),UBERON:0004119(endoderm-derived structure),UBERON:0005178(thoracic cavity element) |
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develops_from: | UBERON:0008947(respiratory primordium) |
part_of: | UBERON:0002224(thoracic cavity),UBERON:0007196(tracheobronchial tree) |
Children
derives from: | FF:0010029 (human trachea - adult sample),FF:0010058 (human trachea - fetal sample) |
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part of: | CL:0000307 (tracheal epithelial cell),CL:0002600 (smooth muscle cell of trachea) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10029-101E2 (trachea, adult, pool1)
- 10058-101H4 (trachea, fetal, donor1)
- 10099-102C9
- 11292-117A5 (Tracheal Epithelial Cells, donor1)
- 11369-118A1 (Tracheal Epithelial Cells, donor2)
- 11441-118I1 (Tracheal Epithelial Cells, donor3)
- 11513-119H1 (Smooth Muscle Cells - Tracheal, donor1)
- 11593-120G9 (Smooth Muscle Cells - Tracheal, donor2)
- 11674-122G9 (Smooth Muscle Cells - Tracheal, donor3)
- 13367-143G1 (Tracheal epithelial cells, differentiation to ciliated epithelial cells)
... further results Mouse (Mus musculus)
- 10029-101E2 (trachea, adult, pool1)
- 10058-101H4 (trachea, fetal, donor1)
- 10099-102C9
- 11292-117A5 (Tracheal Epithelial Cells, donor1)
- 11369-118A1 (Tracheal Epithelial Cells, donor2)
- 11441-118I1 (Tracheal Epithelial Cells, donor3)
- 11513-119H1 (Smooth Muscle Cells - Tracheal, donor1)
- 11593-120G9 (Smooth Muscle Cells - Tracheal, donor2)
- 11674-122G9 (Smooth Muscle Cells - Tracheal, donor3)
- 13367-143G1 (Tracheal epithelial cells, differentiation to ciliated epithelial cells)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003126 (trachea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
1.58e-86 | FFCP PHASE2:Mm9::chr13:115722413..115722430,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:115722413..115722430, + |
1.58e-86 | FFCP PHASE1:Mm9::chr13:72401408..72401416,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:72401408..72401416, - |
1.58e-86 | FFCP PHASE2:Mm9::chr2:164393992..164394012,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:164393992..164394012, - |
1.58e-86 | FFCP PHASE2:Mm9::chr16:32641594..32641601,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr16:32641594..32641601, + |
1.58e-86 | FFCP PHASE2:Mm9::chr4:88696177..88696184,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p2@Gm12603 |
1.58e-86 | FFCP PHASE2:Mm9::chr15:101258041..101258052,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr15:101258041..101258052, + |
1.58e-86 | FFCP PHASE2:Mm9::chr12:17549752..17549763,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr12:17549752..17549763, + |
1.58e-86 | FFCP PHASE2:Mm9::chr5:91198876..91198885,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:91198876..91198885, + |
1.58e-86 | FFCP PHASE2:Mm9::chr17:25885558..25885567,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr17:25885558..25885567, + |
1.58e-86 | FFCP PHASE1:Mm9::chr16:32641594..32641601,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr16:32641594..32641601, + |
1.58e-86 | FFCP PHASE2:Mm9::chr4:88563185..88563192,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr4:88563185..88563192, - |
1.58e-86 | FFCP PHASE1:Mm9::chr6:147205677..147205683,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147205677..147205683, + |
1.58e-86 | FFCP PHASE1:Mm9::chr9:110941233..110941240,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr9:110941233..110941240, + |
1.58e-86 | FFCP PHASE2:Mm9::chr6:147338308..147338339,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147338308..147338339, - |
1.58e-86 | FFCP PHASE2:Mm9::chr11:96608719..96608730,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p1@ENSMUST00000170876, p1@uc011ydj.1 |
1.58e-86 | FFCP PHASE1:Mm9::chr6:147338308..147338339,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147338308..147338339, - |
1.58e-86 | FFCP PHASE1:Mm9::chr13:115644652..115644657,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:115644652..115644657, - |
1.58e-86 | FFCP PHASE2:Mm9::chr3:89487103..89487111,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr3:89487103..89487111, - |
1.58e-86 | FFCP PHASE1:Mm9::chr4:88696144..88696152,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p3@Gm12603 |
1.58e-86 | FFCP PHASE2:Mm9::chr5:91199084..91199088,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:91199084..91199088, - |
1.58e-86 | FFCP PHASE2:Mm9::chr11:4165247..4165267,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:4165247..4165267, + |
1.58e-86 | FFCP PHASE2:Mm9::chr9:110941233..110941240,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr9:110941233..110941240, + |
1.58e-86 | FFCP PHASE1:Mm9::chr15:101258041..101258052,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr15:101258041..101258052, + |
1.58e-86 | FFCP PHASE1:Mm9::chr3:89487103..89487111,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr3:89487103..89487111, - |
1.58e-86 | FFCP PHASE1:Mm9::chr5:91198876..91198885,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:91198876..91198885, + |
1.58e-86 | FFCP PHASE2:Mm9::chr11:86461733..86461747,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:86461733..86461747, - |
1.58e-86 | FFCP PHASE1:Mm9::chr9:110941246..110941254,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr9:110941246..110941254, + |
1.58e-86 | FFCP PHASE1:Mm9::chr2:164389604..164389615,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:164389604..164389615, + |
1.58e-86 | FFCP PHASE2:Mm9::chr5:135420996..135421000,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:135420996..135421000, + |
1.58e-86 | FFCP PHASE1:Mm9::chr2:60538178..60538182,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:60538178..60538182, - |
1.58e-86 | FFCP PHASE2:Mm9::chr13:72401408..72401416,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:72401408..72401416, - |
1.58e-86 | FFCP PHASE2:Mm9::chr11:100006864..100006873,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:100006864..100006873, + |
1.58e-86 | FFCP PHASE2:Mm9::chr13:115644652..115644657,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:115644652..115644657, - |
1.58e-86 | FFCP PHASE1:Mm9::chr4:88696177..88696184,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p2@Gm12603 |
1.58e-86 | FFCP PHASE1:Mm9::chr17:25885558..25885567,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr17:25885558..25885567, + |
1.58e-86 | FFCP PHASE2:Mm9::chr9:110941246..110941254,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr9:110941246..110941254, + |
1.58e-86 | FFCP PHASE1:Mm9::chr11:86461733..86461747,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:86461733..86461747, - |
1.58e-86 | FFCP PHASE1:Mm9::chr5:91199084..91199088,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:91199084..91199088, - |
1.58e-86 | FFCP PHASE1:Mm9::chr1:108303887..108303893,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr1:108303887..108303893, + |
1.58e-86 | FFCP PHASE1:Mm9::chr2:164393992..164394012,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:164393992..164394012, - |
1.58e-86 | FFCP PHASE2:Mm9::chr1:151954385..151954387,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr1:151954385..151954387, + |
1.58e-86 | FFCP PHASE2:Mm9::chr5:135422125..135422141,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:135422125..135422141, - |
1.58e-86 | FFCP PHASE1:Mm9::chr11:4165247..4165267,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:4165247..4165267, + |
1.58e-86 | FFCP PHASE2:Mm9::chr6:147205603..147205610,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147205603..147205610, + |
1.58e-86 | FFCP PHASE1:Mm9::chr13:115722413..115722430,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr13:115722413..115722430, + |
1.58e-86 | FFCP PHASE2:Mm9::chr2:164389604..164389615,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:164389604..164389615, + |
1.58e-86 | FFCP PHASE1:Mm9::chr5:135422125..135422141,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:135422125..135422141, - |
1.58e-86 | FFCP PHASE2:Mm9::chr4:88696144..88696152,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p3@Gm12603 |
1.58e-86 | FFCP PHASE1:Mm9::chr1:151954385..151954387,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr1:151954385..151954387, + |
1.58e-86 | FFCP PHASE1:Mm9::chr11:100006864..100006873,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr11:100006864..100006873, + |
1.58e-86 | FFCP PHASE2:Mm9::chr1:108303887..108303893,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr1:108303887..108303893, + |
1.58e-86 | FFCP PHASE1:Mm9::chr4:88563185..88563192,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr4:88563185..88563192, - |
1.58e-86 | FFCP PHASE1:Mm9::chr11:96608719..96608730,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p1@ENSMUST00000170876, p1@uc011ydj.1 |
1.58e-86 | FFCP PHASE1:Mm9::chr5:135420996..135421000,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr5:135420996..135421000, + |
1.58e-86 | FFCP PHASE2:Mm9::chr6:147205677..147205683,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147205677..147205683, + |
1.58e-86 | FFCP PHASE2:Mm9::chr2:60538178..60538182,-#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr2:60538178..60538182, - |
1.58e-86 | FFCP PHASE1:Mm9::chr12:17549752..17549763,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr12:17549752..17549763, + |
1.58e-86 | FFCP PHASE1:Mm9::chr6:147205603..147205610,+#_d56e7ff488a3086bb8e3c0fe2b8a6ebb | p@chr6:147205603..147205610, + |
1.33e-65 | FFCP PHASE2:Mm9::chr19:47939269..47939279,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr19:47939269..47939279, - |
1.33e-65 | FFCP PHASE2:Mm9::chr3:121437587..121437593,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:121437587..121437593, + |
1.33e-65 | FFCP PHASE1:Mm9::chr3:121437587..121437593,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:121437587..121437593, + |
1.33e-65 | FFCP PHASE2:Mm9::chr14:34905716..34905718,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr14:34905716..34905718, + |
1.33e-65 | FFCP PHASE2:Mm9::chr11:100002128..100002131,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:100002128..100002131, + |
1.33e-65 | FFCP PHASE2:Mm9::chr11:4164303..4164316,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:4164303..4164316, + |
1.33e-65 | FFCP PHASE2:Mm9::chr11:29642912..29642916,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:29642912..29642916, - |
1.33e-65 | FFCP PHASE1:Mm9::chr19:47932377..47932386,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr19:47932377..47932386, - |
1.33e-65 | FFCP PHASE2:Mm9::chrX:20383628..20383635,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chrX:20383628..20383635, + |
1.33e-65 | FFCP PHASE2:Mm9::chr14:31386795..31386797,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr14:31386795..31386797, - |
1.33e-65 | FFCP PHASE1:Mm9::chr11:29642912..29642916,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:29642912..29642916, - |
1.33e-65 | FFCP PHASE1:Mm9::chr11:100002128..100002131,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:100002128..100002131, + |
1.33e-65 | FFCP PHASE1:Mm9::chr14:34905716..34905718,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr14:34905716..34905718, + |
1.33e-65 | FFCP PHASE1:Mm9::chr3:90392458..90392472,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:90392458..90392472, + |
1.33e-65 | FFCP PHASE1:Mm9::chr11:4164303..4164316,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr11:4164303..4164316, + |
1.33e-65 | FFCP PHASE1:Mm9::chr2:144564146..144564166,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p3@Dtd1 |
1.33e-65 | FFCP PHASE2:Mm9::chr2:144564146..144564166,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p3@Dtd1 |
1.33e-65 | FFCP PHASE2:Mm9::chr6:147212620..147212625,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr6:147212620..147212625, + |
1.33e-65 | FFCP PHASE2:Mm9::chr3:90392458..90392472,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:90392458..90392472, + |
1.33e-65 | FFCP PHASE2:Mm9::chr3:121437538..121437546,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:121437538..121437546, + |
1.33e-65 | FFCP PHASE1:Mm9::chr6:147212620..147212625,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr6:147212620..147212625, + |
1.33e-65 | FFCP PHASE1:Mm9::chr3:121437538..121437546,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr3:121437538..121437546, + |
1.33e-65 | FFCP PHASE2:Mm9::chr19:47932377..47932386,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr19:47932377..47932386, - |
1.33e-65 | FFCP PHASE1:Mm9::chr19:47939269..47939279,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr19:47939269..47939279, - |
1.33e-65 | FFCP PHASE1:Mm9::chr14:31386795..31386797,-#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chr14:31386795..31386797, - |
1.33e-65 | FFCP PHASE1:Mm9::chrX:20383628..20383635,+#_4ded33160ead9e40cbee21cb3a5c88b0 | p@chrX:20383628..20383635, + |
6.04e-65 | FFCP PHASE1:Mm9::chr1:90456476..90456498,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr1:90456476..90456498, + |
6.04e-65 | FFCP PHASE2:Mm9::chr15:38385124..38385138,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr15:38385124..38385138, + |
6.04e-65 | FFCP PHASE2:Mm9::chr19:47928736..47928764,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr19:47928736..47928764, + |
6.04e-65 | FFCP PHASE1:Mm9::chr15:38385124..38385138,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr15:38385124..38385138, + |
6.04e-65 | FFCP PHASE2:Mm9::chr17:25888467..25888513,-#_90549327e4f18fdf422f4eef2d52d68b | p@chr17:25888467..25888513, - |
6.04e-65 | FFCP PHASE1:Mm9::chr19:47928736..47928764,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr19:47928736..47928764, + |
6.04e-65 | FFCP PHASE2:Mm9::chr1:90456476..90456498,+#_90549327e4f18fdf422f4eef2d52d68b | p@chr1:90456476..90456498, + |
6.04e-65 | FFCP PHASE1:Mm9::chr17:25888467..25888513,-#_90549327e4f18fdf422f4eef2d52d68b | p@chr17:25888467..25888513, - |
4.76e-57 | FFCP PHASE2:Hg19::chr5:180017253..180017257,-#_f6bcfe52fcaf0ec855de165c456c693e | p@chr5:180017253..180017257, - |
4.76e-57 | FFCP PHASE1:Hg19::chr5:180017253..180017257,-#_f6bcfe52fcaf0ec855de165c456c693e | p@chr5:180017253..180017257, - |
4.9e-53 | FFCP PHASE1:Mm9::chr12:8799233..8799252,+#_7ea9a598a3122a692ade973287b92408 | p@chr12:8799233..8799252, + |
4.9e-53 | FFCP PHASE2:Mm9::chr5:103804464..103804467,+#_7ea9a598a3122a692ade973287b92408 | p@chr5:103804464..103804467, + |
4.9e-53 | FFCP PHASE2:Mm9::chr11:94958540..94958582,+#_7ea9a598a3122a692ade973287b92408 | p@chr11:94958540..94958582, + |
4.9e-53 | FFCP PHASE2:Mm9::chr6:147212455..147212462,-#_7ea9a598a3122a692ade973287b92408 | p6@Pthlh |
4.9e-53 | FFCP PHASE1:Mm9::chr17:71105425..71105430,+#_7ea9a598a3122a692ade973287b92408 | p@chr17:71105425..71105430, + |
4.9e-53 | FFCP PHASE2:Mm9::chrX:163645025..163645028,+#_7ea9a598a3122a692ade973287b92408 | p@chrX:163645025..163645028, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "An elongated tube which carries air to and from the lungs.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.