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{{CL
{{CL
|id=CL:0000669
|alt_id=CL:0000184
|name=pericyte;;pericyte cell
|namespace=cell;;efo
|def="An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907]
|xref=BTO:0002441;;FMA:63174
|is_a=CL:0000183;;CL:0000630;;CL:0000988;;CL:0002320
|synonym="adventitial cell" RELATED [];;"adventitial reticular cell" EXACT [];;"ARC" EXACT [PMID:17986482];;"cell of Rouget" EXACT [];;"pericyte" EXACT [];;"pericyte of Rouget" EXACT []
|comment=Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive,  SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.
|comment=Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive,  SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.
|alt_id=CL:0000184
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000669
|is_a=CL:0000183 ;;CL:0000630 ;;CL:0002320
|is_obsolete=
|located_in=
|located_in=
|name=pericyte;;pericyte cell
|namespace=cell;;efo
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="adventitial cell" RELATED [];;"adventitial reticular cell" EXACT [];;"ARC" EXACT [PMID:17986482];;"cell of Rouget" EXACT [];;"pericyte" EXACT [];;"pericyte of Rouget" EXACT []
|union_of=
|xref=BTO:0002441;;FMA:63174
}}
}}

Revision as of 10:19, 12 September 2014

Name:pericyte;;pericyte cell
Namespace:cell;;efo
Definition:"An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907]
Xrefs:
links:

BTO:0002441

FMA:63174
Synonyms: "adventitial cell" RELATED []
"adventitial reticular cell" EXACT []
"ARC" EXACT [PMID:17986482]
"cell of Rouget" EXACT []
"pericyte" EXACT []
"pericyte of Rouget" EXACT []
Comments:Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.
Alt_id: CL:0000184


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000183(contractile cell),CL:0000630(supportive cell),CL:0002320(connective tissue cell)



Children


is a:CL:0000650 (mesangial cell),CL:0002575 (central nervous system pericyte),CL:1001318 (renal interstitial pericyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000669 (pericyte;;pericyte cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.4e-66FFCP PHASE2:Hg19::chr15:57598803..57598812,+#_aeec4a401a145916983f5d26cb11d206p6@LOC283663
2.4e-66FFCP PHASE1:Hg19::chr15:57598803..57598812,+#_aeec4a401a145916983f5d26cb11d206p6@LOC283663
3.1e-50FFCP PHASE1:Hg19::chr13:75493774..75493776,-#_07a266773064eb5884d153ef9f3d7740p@chr13:75493774..75493776, -
3.1e-50FFCP PHASE2:Hg19::chr18:8054314..8054316,-#_07a266773064eb5884d153ef9f3d7740p@chr18:8054314..8054316, -
3.1e-50FFCP PHASE2:Hg19::chr5:149515832..149515837,-#_07a266773064eb5884d153ef9f3d7740p@chr5:149515832..149515837, -
3.1e-50FFCP PHASE2:Hg19::chr13:75493774..75493776,-#_07a266773064eb5884d153ef9f3d7740p@chr13:75493774..75493776, -
3.1e-50FFCP PHASE1:Hg19::chr5:149515832..149515837,-#_07a266773064eb5884d153ef9f3d7740p@chr5:149515832..149515837, -
3.1e-50FFCP PHASE1:Hg19::chr18:8054314..8054316,-#_07a266773064eb5884d153ef9f3d7740p@chr18:8054314..8054316, -
1.48e-40FFCP PHASE2:Hg19::chr12:279860..279871,+#_5ae6c7cd6c8cc5ec888609a4e2114fa1p@chr12:279860..279871, +
1.48e-40FFCP PHASE1:Hg19::chr12:279860..279871,+#_5ae6c7cd6c8cc5ec888609a4e2114fa1p@chr12:279860..279871, +
2.22e-40FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_e905070ba1ec5fa3fb37603b22b037acp@chr2:133426030..133426041, -
2.22e-40FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_e905070ba1ec5fa3fb37603b22b037acp@chr2:133426030..133426041, -
2.22e-40FFCP PHASE1:Hg19::chr11:61634723..61634731,+#_e905070ba1ec5fa3fb37603b22b037acp@chr11:61634723..61634731, +
2.22e-40FFCP PHASE2:Hg19::chr11:61634723..61634731,+#_e905070ba1ec5fa3fb37603b22b037acp@chr11:61634723..61634731, +
2.71e-40FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_955f95a6cf04143a460eaa850259aee1p23@TTC39A
2.71e-40FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_955f95a6cf04143a460eaa850259aee1p23@TTC39A
4.94e-40FFCP PHASE1:Hg19::chr13:100634777..100634788,+#_5f27ab464d834ccd0fc5fd771973d730p13@ZIC2
4.94e-40FFCP PHASE2:Hg19::chr13:100634777..100634788,+#_5f27ab464d834ccd0fc5fd771973d730p13@ZIC2
4.28e-34FFCP PHASE2:Hg19::chr17:75471711..75471726,+#_3887052e1655cb3413918fb3c99d3b96p73@SEPT9
4.28e-34FFCP PHASE1:Hg19::chr5:149532703..149532711,+#_3887052e1655cb3413918fb3c99d3b96p@chr5:149532703..149532711, +
4.28e-34FFCP PHASE1:Hg19::chr17:75471711..75471726,+#_3887052e1655cb3413918fb3c99d3b96p73@SEPT9
4.28e-34FFCP PHASE2:Hg19::chr5:149532703..149532711,+#_3887052e1655cb3413918fb3c99d3b96p@chr5:149532703..149532711, +
7.07e-34FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_2ac75917a87dc84f3211b931853d8950p@chr2:133426106..133426117, -
7.07e-34FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_2ac75917a87dc84f3211b931853d8950p@chr2:133426106..133426117, -
8.36e-34FFCP PHASE2:Hg19::chr11:62752310..62752313,-#_1ef6c73b80808248189cda402d47e206p7@SLC22A6
8.36e-34FFCP PHASE1:Hg19::chr11:62752310..62752313,-#_1ef6c73b80808248189cda402d47e206p7@SLC22A6
1.78e-29FFCP PHASE1:Hg19::chr3:147128048..147128057,+#_540f712452258d5e34e35524d573b316p4@AB464362
1.78e-29FFCP PHASE2:Hg19::chr3:147109858..147109861,+#_540f712452258d5e34e35524d573b316p@chr3:147109858..147109861, +
1.78e-29FFCP PHASE1:Hg19::chr5:149537789..149537803,-#_540f712452258d5e34e35524d573b316p@chr5:149537789..149537803, -
1.78e-29FFCP PHASE2:Hg19::chr3:147128048..147128057,+#_540f712452258d5e34e35524d573b316p4@AB464362
1.78e-29FFCP PHASE2:Hg19::chr5:149537789..149537803,-#_540f712452258d5e34e35524d573b316p@chr5:149537789..149537803, -
1.78e-29FFCP PHASE1:Hg19::chr3:147109858..147109861,+#_540f712452258d5e34e35524d573b316p@chr3:147109858..147109861, +
4.21e-29FFCP PHASE2:Hg19::chr12:15941738..15941768,+#_a03a35f5fcb2bd234c93c09895b28f4fp@chr12:15941738..15941768, +
4.21e-29FFCP PHASE1:Hg19::chr12:15941738..15941768,+#_a03a35f5fcb2bd234c93c09895b28f4fp@chr12:15941738..15941768, +
4.86e-29FFCP PHASE2:Hg19::chr17:26890530..26890545,-#_84152ef46a4dce4a489e839fbe00354dp@chr17:26890530..26890545, -
4.86e-29FFCP PHASE1:Hg19::chr17:26890530..26890545,-#_84152ef46a4dce4a489e839fbe00354dp@chr17:26890530..26890545, -
8.39e-27FFCP PHASE2:Hg19::chr6:94129519..94129544,+#_28bd2271272ffb18431d1af2555409a5p@chr6:94129519..94129544, +
8.39e-27FFCP PHASE1:Hg19::chr6:94129519..94129544,+#_28bd2271272ffb18431d1af2555409a5p@chr6:94129519..94129544, +
9.17e-27FFCP PHASE2:Hg19::chr22:37945945..37945963,+#_dc296454577b29adc0299c2e039f4687p1@ENST00000428838
9.17e-27FFCP PHASE1:Hg19::chr22:37945945..37945963,+#_dc296454577b29adc0299c2e039f4687p1@ENST00000428838
5.23e-26FFCP PHASE2:Hg19::chr3:147128031..147128038,+#_3cb1f65de5943aab6fe0d4133575c25ep7@AB464362
5.23e-26FFCP PHASE1:Hg19::chr3:147128031..147128038,+#_3cb1f65de5943aab6fe0d4133575c25ep7@AB464362
5.56e-26FFCP PHASE1:Hg19::chr11:65061637..65061642,+#_73291a0c52157f46c60d3d7fa45e0080p13@POLA2
5.56e-26FFCP PHASE2:Hg19::chr11:65061637..65061642,+#_73291a0c52157f46c60d3d7fa45e0080p13@POLA2
5.56e-26FFCP PHASE1:Hg19::chr19:48281847..48281853,+#_73291a0c52157f46c60d3d7fa45e0080p7@SEPW1
5.56e-26FFCP PHASE2:Hg19::chr11:67186174..67186179,+#_73291a0c52157f46c60d3d7fa45e0080p@chr11:67186174..67186179, +
5.56e-26FFCP PHASE2:Hg19::chr19:48281847..48281853,+#_73291a0c52157f46c60d3d7fa45e0080p7@SEPW1
5.56e-26FFCP PHASE1:Hg19::chr11:67186174..67186179,+#_73291a0c52157f46c60d3d7fa45e0080p@chr11:67186174..67186179, +
6.73e-26FFCP PHASE1:Hg19::chr10:102495136..102495146,+#_deae222fb1ef53d2bbbcee9e566a7ea5p8@PAX2
6.73e-26FFCP PHASE2:Hg19::chr10:102495136..102495146,+#_deae222fb1ef53d2bbbcee9e566a7ea5p8@PAX2
6.73e-26FFCP PHASE1:Hg19::chr10:134535354..134535366,-#_deae222fb1ef53d2bbbcee9e566a7ea5p@chr10:134535354..134535366, -
6.73e-26FFCP PHASE2:Hg19::chr10:134535354..134535366,-#_deae222fb1ef53d2bbbcee9e566a7ea5p@chr10:134535354..134535366, -
7.14e-26FFCP PHASE2:Hg19::chr5:148609626..148609631,+#_4a4a041d7c5c235f9cecad29771dae26p@chr5:148609626..148609631, +
7.14e-26FFCP PHASE2:Hg19::chr9:81641483..81641491,-#_4a4a041d7c5c235f9cecad29771dae26p@chr9:81641483..81641491, -
7.14e-26FFCP PHASE1:Hg19::chr6:31848961..31848968,-#_4a4a041d7c5c235f9cecad29771dae26p@chr6:31848961..31848968, -
7.14e-26FFCP PHASE2:Hg19::chr17:56614878..56614885,-#_4a4a041d7c5c235f9cecad29771dae26p@chr17:56614878..56614885, -
7.14e-26FFCP PHASE2:Hg19::chr14:23574150..23574161,-#_4a4a041d7c5c235f9cecad29771dae26p2@uc010aki.1
7.14e-26FFCP PHASE2:Hg19::chr1:201399370..201399380,-#_4a4a041d7c5c235f9cecad29771dae26p8@TNNI1
7.14e-26FFCP PHASE2:Hg19::chr8:144875310..144875315,-#_4a4a041d7c5c235f9cecad29771dae26p19@SCRIB
7.14e-26FFCP PHASE2:Hg19::chr19:48283768..48283781,+#_4a4a041d7c5c235f9cecad29771dae26p@chr19:48283768..48283781, +
7.14e-26FFCP PHASE1:Hg19::chr3:165929277..165929294,-#_4a4a041d7c5c235f9cecad29771dae26p@chr3:165929277..165929294, -
7.14e-26FFCP PHASE1:Hg19::chr5:148609626..148609631,+#_4a4a041d7c5c235f9cecad29771dae26p@chr5:148609626..148609631, +
7.14e-26FFCP PHASE1:Hg19::chr20:32850613..32850632,+#_4a4a041d7c5c235f9cecad29771dae26p@chr20:32850613..32850632, +
7.14e-26FFCP PHASE2:Hg19::chr6:31848961..31848968,-#_4a4a041d7c5c235f9cecad29771dae26p@chr6:31848961..31848968, -
7.14e-26FFCP PHASE1:Hg19::chr10:102505655..102505689,+#_4a4a041d7c5c235f9cecad29771dae26p10@PAX2
7.14e-26FFCP PHASE2:Hg19::chr10:102505655..102505689,+#_4a4a041d7c5c235f9cecad29771dae26p10@PAX2
7.14e-26FFCP PHASE1:Hg19::chr17:56614878..56614885,-#_4a4a041d7c5c235f9cecad29771dae26p@chr17:56614878..56614885, -
7.14e-26FFCP PHASE1:Hg19::chr9:81641483..81641491,-#_4a4a041d7c5c235f9cecad29771dae26p@chr9:81641483..81641491, -
7.14e-26FFCP PHASE2:Hg19::chr3:165929277..165929294,-#_4a4a041d7c5c235f9cecad29771dae26p@chr3:165929277..165929294, -
7.14e-26FFCP PHASE1:Hg19::chr10:35894364..35894370,+#_4a4a041d7c5c235f9cecad29771dae26p4@GJD4
7.14e-26FFCP PHASE2:Hg19::chr10:35894364..35894370,+#_4a4a041d7c5c235f9cecad29771dae26p4@GJD4
7.14e-26FFCP PHASE1:Hg19::chr19:48283768..48283781,+#_4a4a041d7c5c235f9cecad29771dae26p@chr19:48283768..48283781, +
7.14e-26FFCP PHASE1:Hg19::chr14:23574150..23574161,-#_4a4a041d7c5c235f9cecad29771dae26p2@uc010aki.1
7.14e-26FFCP PHASE1:Hg19::chr1:201399370..201399380,-#_4a4a041d7c5c235f9cecad29771dae26p8@TNNI1
7.14e-26FFCP PHASE1:Hg19::chr8:144875310..144875315,-#_4a4a041d7c5c235f9cecad29771dae26p19@SCRIB
7.14e-26FFCP PHASE2:Hg19::chr20:32850613..32850632,+#_4a4a041d7c5c235f9cecad29771dae26p@chr20:32850613..32850632, +
8.56e-26FFCP PHASE2:Hg19::chr17:75446774..75446783,+#_544e4ef0c35f67f4723a7e60e4d7af19p49@SEPT9
8.56e-26FFCP PHASE1:Hg19::chr17:75446774..75446783,+#_544e4ef0c35f67f4723a7e60e4d7af19p49@SEPT9
9.82e-26FFCP PHASE2:Hg19::chr17:17480803..17480814,-#_e15ce64699966ad0a7c04b32dfd85f98p19@PEMT
9.82e-26FFCP PHASE1:Hg19::chr17:17480803..17480814,-#_e15ce64699966ad0a7c04b32dfd85f98p19@PEMT
1.43e-25FFCP PHASE1:Hg19::chr14:98348860..98348862,-#_be025c17982f13f97a86a5e3b0468f3cp@chr14:98348860..98348862, -
1.43e-25FFCP PHASE2:Hg19::chr14:98348860..98348862,-#_be025c17982f13f97a86a5e3b0468f3cp@chr14:98348860..98348862, -
1.65e-23FFCP PHASE1:Hg19::chr1:155224987..155224998,-#_2bf348a8e4c97d62d7dd1a625e2d4541p8@FAM189B
1.65e-23FFCP PHASE2:Hg19::chr1:155224987..155224998,-#_2bf348a8e4c97d62d7dd1a625e2d4541p8@FAM189B
2.63e-23FFCP PHASE1:Hg19::chr17:48346424..48346435,+#_419950981da7749abedde04ede78c89cp@chr17:48346424..48346435, +
2.63e-23FFCP PHASE2:Hg19::chr17:48346424..48346435,+#_419950981da7749abedde04ede78c89cp@chr17:48346424..48346435, +
2.94e-23FFCP PHASE1:Hg19::chr11:73020686..73020697,+#_8273fcc573d96e38a068e5e4c6a7ea77p23@ARHGEF17
2.94e-23FFCP PHASE2:Hg19::chr11:73020686..73020697,+#_8273fcc573d96e38a068e5e4c6a7ea77p23@ARHGEF17
5.14e-23FFCP PHASE1:Hg19::chr11:60680190..60680212,+#_20ee9a99a15fde7a638d1031f3a78ef8p@chr11:60680190..60680212, +
5.14e-23FFCP PHASE2:Hg19::chr11:60680190..60680212,+#_20ee9a99a15fde7a638d1031f3a78ef8p@chr11:60680190..60680212, +
5.75e-23FFCP PHASE2:Hg19::chr4:167520111..167520112,-#_be26b6a471af313cc25dbfa59144e438p@chr4:167520111..167520112, -
5.75e-23FFCP PHASE1:Hg19::chr4:167520111..167520112,-#_be26b6a471af313cc25dbfa59144e438p@chr4:167520111..167520112, -
6.42e-23FFCP PHASE2:Hg19::chr5:158523468..158523481,-#_90ba5bfe133a310b7175cd0b14445a6ep20@EBF1
6.42e-23FFCP PHASE1:Hg19::chr5:158523468..158523481,-#_90ba5bfe133a310b7175cd0b14445a6ep20@EBF1
7.18e-23FFCP PHASE2:Hg19::chr19:46806885..46806888,+#_857b56fe41d81e240c0401e69f0981ccp11@HIF3A
7.18e-23FFCP PHASE1:Hg19::chr19:46806885..46806888,+#_857b56fe41d81e240c0401e69f0981ccp11@HIF3A
1.0e-22FFCP PHASE1:Hg19::chr11:2179591..2179596,-#_9b744c1b8c48467b5cc806498ef0413ap5@INS-IGF2
1.0e-22FFCP PHASE2:Hg19::chr11:2179591..2179596,-#_9b744c1b8c48467b5cc806498ef0413ap5@INS-IGF2
2.72e-21FFCP PHASE1:Hg19::chr17:75446704..75446713,+#_f71225512411f9f73e0f456e3efb3a8cp35@SEPT9
2.72e-21FFCP PHASE2:Hg19::chr17:75446704..75446713,+#_f71225512411f9f73e0f456e3efb3a8cp35@SEPT9

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