MCL coexpression mm9:1765

Phase1 CAGE Peaks

	Short description
Mm9::chr2:125331693..125331713,-	p4@Fbn1
Mm9::chr2:125332131..125332144,-	p2@Fbn1
Mm9::chr2:125332155..125332181,-	p1@Fbn1
Mm9::chr8:71404549..71404571,+	p2@Lpl
Mm9::chr9:63932714..63932725,+	p@chr9:63932714..63932725 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004465	lipoprotein lipase activity	0.00671012245769187
GO:0001527	microfibril	0.00671012245769187
GO:0043205	fibril	0.00671012245769187
GO:0042627	chylomicron	0.00671012245769187
GO:0005319	lipid transporter activity	0.0273657566549681
GO:0008201	heparin binding	0.0273657566549681
GO:0005201	extracellular matrix structural constituent	0.0273657566549681
GO:0016298	lipase activity	0.0273657566549681
GO:0005539	glycosaminoglycan binding	0.0273657566549681
GO:0030247	polysaccharide binding	0.0273657566549681
GO:0001871	pattern binding	0.0273657566549681
GO:0044420	extracellular matrix part	0.0273657566549681
GO:0016042	lipid catabolic process	0.0273657566549681
GO:0004091	carboxylesterase activity	0.0284080843440949
GO:0048503	GPI anchor binding	0.0286125319865822
GO:0044421	extracellular region part	0.0286125319865822
GO:0035091	phosphoinositide binding	0.0368311374064348
GO:0005543	phospholipid binding	0.0423786640757882

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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