MCL coexpression mm9:1547

Phase1 CAGE Peaks

	Short description
Mm9::chr11:109224085..109224168,+	p1@Gna13
Mm9::chr11:109224169..109224182,+	p4@Gna13
Mm9::chr11:109224197..109224221,+	p3@Gna13
Mm9::chr11:93857396..93857413,+	p1@Spag9
Mm9::chr8:125566132..125566143,-	p3@Ankrd11

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008432	JUN kinase binding	0.0260166174162555
GO:0007243	protein kinase cascade	0.0260166174162555
GO:0019894	kinesin binding	0.046628077004361
GO:0030168	platelet activation	0.046628077004361
GO:0051260	protein homooligomerization	0.046628077004361
GO:0001569	patterning of blood vessels	0.046628077004361
GO:0051259	protein oligomerization	0.046628077004361
GO:0005834	heterotrimeric G-protein complex	0.046628077004361
GO:0000187	activation of MAPK activity	0.046628077004361
GO:0009880	embryonic pattern specification	0.046628077004361
GO:0043406	positive regulation of MAP kinase activity	0.046628077004361
GO:0022603	regulation of anatomical structure morphogenesis	0.046628077004361
GO:0008360	regulation of cell shape	0.046628077004361
GO:0022604	regulation of cell morphogenesis	0.046628077004361
GO:0019901	protein kinase binding	0.046628077004361
GO:0019897	extrinsic to plasma membrane	0.046628077004361
GO:0019900	kinase binding	0.046628077004361
GO:0007242	intracellular signaling cascade	0.046628077004361
GO:0007596	blood coagulation	0.046628077004361
GO:0030334	regulation of cell migration	0.046628077004361
GO:0007599	hemostasis	0.046628077004361
GO:0050817	coagulation	0.046628077004361
GO:0048754	branching morphogenesis of a tube	0.046628077004361
GO:0051270	regulation of cell motility	0.046628077004361
GO:0043405	regulation of MAP kinase activity	0.046628077004361
GO:0001763	morphogenesis of a branching structure	0.046628077004361
GO:0040012	regulation of locomotion	0.046628077004361
GO:0019898	extrinsic to membrane	0.0482174233874129
GO:0050878	regulation of body fluid levels	0.0482174233874129

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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