MCL coexpression mm9:1580

Phase1 CAGE Peaks

	Short description
Mm9::chr11:69660112..69660161,+	p1@Plscr3
Mm9::chr14:21514178..21514207,+	p1@Fut11
Mm9::chr2:118752232..118752290,+	p1@Chst14
Mm9::chr2:118752291..118752311,+	p2@Chst14
Mm9::chr2:118752312..118752344,+	p3@Chst14

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	0.00320495261052977
GO:0030205	dermatan sulfate metabolic process	0.00320495261052977
GO:0030208	dermatan sulfate biosynthetic process	0.00320495261052977
GO:0050655	dermatan sulfate proteoglycan metabolic process	0.00320495261052977
GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity	0.00549360244756628
GO:0030206	chondroitin sulfate biosynthetic process	0.00549360244756628
GO:0030204	chondroitin sulfate metabolic process	0.00549360244756628
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	0.00712055615693433
GO:0050654	chondroitin sulfate proteoglycan metabolic process	0.00712055615693433
GO:0006024	glycosaminoglycan biosynthetic process	0.00815537962692766
GO:0006023	aminoglycan biosynthetic process	0.00815537962692766
GO:0008417	fucosyltransferase activity	0.0117450554949872
GO:0030166	proteoglycan biosynthetic process	0.0121668129786169
GO:0005794	Golgi apparatus	0.0121668129786169
GO:0042632	cholesterol homeostasis	0.0121668129786169
GO:0055088	lipid homeostasis	0.0121668129786169
GO:0055092	sterol homeostasis	0.0121668129786169
GO:0006029	proteoglycan metabolic process	0.0121668129786169
GO:0006022	aminoglycan metabolic process	0.0121668129786169
GO:0030203	glycosaminoglycan metabolic process	0.0121668129786169
GO:0009059	macromolecule biosynthetic process	0.013359548991871
GO:0042593	glucose homeostasis	0.0154668522003998
GO:0033500	carbohydrate homeostasis	0.0154668522003998
GO:0044272	sulfur compound biosynthetic process	0.0154668522003998
GO:0008146	sulfotransferase activity	0.022509751156262
GO:0016782	transferase activity, transferring sulfur-containing groups	0.0250777257891718
GO:0006790	sulfur metabolic process	0.0283964755883061
GO:0009058	biosynthetic process	0.0311107170377084
GO:0006486	protein amino acid glycosylation	0.0325304211573446
GO:0043413	biopolymer glycosylation	0.0325304211573446
GO:0016051	carbohydrate biosynthetic process	0.0325304211573446
GO:0009101	glycoprotein biosynthetic process	0.0334992009021274
GO:0009100	glycoprotein metabolic process	0.0378689794229424

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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