UBERON:0001264: Difference between revisions
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|id=UBERON:0001264 | |id=UBERON:0001264 | ||
|is_a=UBERON:0002075 | |is_a=UBERON:0002075 | ||
|is_obsolete= | |is_obsolete= | ||
|located_in= | |located_in= | ||
Revision as of 11:02, 12 September 2014
| Name: | pancreas | ||
|---|---|---|---|
| Definition: | "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. The mature pancreas of higher vertebrates and mammals comprises two major functional units: the exocrine pancreas, which is responsible for the production of digestive enzymes to be secreted into the gut lumen, and the endocrine pancreas, which has its role in the synthesis of several hormones with key regulatory functions in food uptake and metabolism. The exocrine portion constitutes the majority of the mass of the pancreas, and contains only two different cell types, the secretory acinar cells and the ductular cells. The endocrine portion, which comprises only 1遯ｶ�2% of the total mass, contains five different cell types, which are organized into mixed functional assemblies referred to as the islets of Langerhans[PMID]." [GO:0031016, PMID:16417468, Wikipedia:Pancreas] | ||
| Xrefs: |
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| Comments: | taxon notes: As a secretory organ serving exocrine and endocrine functions, the pancreas is specific to the vertebrates[PMID:16417468] Hagfishes and lampreys are unique in the complete separation of their endocrine pancreas (islet or- gan) and their exocrine pancreas (50). The endocrine and exocrine pancreas are coassociated in crown gnathostomes (50). In Branchiostoma and Ciona, there is no diverticulum as there is in hagfishes, lampreys, and gnathostomes, only dispersed insulin-secreting cells in the walls of the gastrointestinal tract (51, 52) [PMID:20959416] | ||
| Alt_id: | UBERON:FMA_16017-FMA_16018-FMA_7198-MA_0000120-MA_0001582-MA_0002415-MIAA_0000075-XAO_0000136-XAO_0000137-ZFA_0000140-ZFA_0001249-ZFA_0001260 | ||
| Subset: |
major_organ organ_slim uberon_slim vertebrate_core |
200px-Illu_pancrease.svg.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0002075(viscus) |
|---|---|
| part_of: | UBERON:0000949(endocrine system) |
Children
| is a: | FF:10603-108E9 (embryonic pancreas cell line:2C6),FF:10604-108F1 (embryonic pancreas cell line:1B2C6),FF:10605-108F2 (embryonic pancreas cell line:1C3D3),FF:10606-108F3 (embryonic pancreas cell line:1C3IKEI) |
|---|---|
| derives from: | FF:0010049 (human pancreas - adult sample),FF:0011251 (mouse pancreas- neonate N01 sample),FF:0011253 (mouse pancreas- embryo E18 sample),FF:0011254 (mouse pancreas- neonate N02 sample),FF:0011255 (mouse pancreas- neonate N30 sample),FF:0011256 (mouse pancreas- neonate N25 sample),FF:0011257 (mouse pancreas- embryo E15 sample),FF:0011258 (mouse pancreas- embryo E17 sample),FF:0011262 (mouse pancreas- embryo E14 sample),FF:0011263 (mouse pancreas- embryo E16 sample),FF:0011266 (mouse pancreas- neonate N00 sample),FF:0011267 (mouse pancreas- neonate N16 sample),FF:0011315 (mouse pancreas- adult sample),FF:0100794 (pancreatic cancer cell line sample) |
| part of: | UBERON:0000016 (endocrine pancreas),CL:0000083 (epithelial cell of pancreas),CL:0000173 (pancreatic D cell),CL:0002574 (stromal cell of pancreas),UBERON:0007329 (pancreatic duct) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10049-101G4 (pancreas, adult, donor1)
- 10438-106E6 (ductal cell carcinoma cell line:KLM-1)
- 10488-107B2 (ductal cell carcinoma cell line:MIA Paca2)
- 10489-107B3
- 10531-107F9
- 10542-107H2
- 10543-107H3
- 10603-108E9 (embryonic pancreas cell line:2C6)
- 10604-108F1 (embryonic pancreas cell line:1B2C6)
- 10605-108F2 (embryonic pancreas cell line:1C3D3)
... further results Mouse (Mus musculus)
- 10049-101G4 (pancreas, adult, donor1)
- 10438-106E6 (ductal cell carcinoma cell line:KLM-1)
- 10488-107B2 (ductal cell carcinoma cell line:MIA Paca2)
- 10489-107B3
- 10531-107F9
- 10542-107H2
- 10543-107H3
- 10603-108E9 (embryonic pancreas cell line:2C6)
- 10604-108F1 (embryonic pancreas cell line:1B2C6)
- 10605-108F2 (embryonic pancreas cell line:1C3D3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001264 (pancreas), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.31e-86 | FFCP PHASE2:Mm9::chr19:58804381..58804392,+#_95623124942f1e1aa240aa22e89ee361 | p@chr19:58804381..58804392, + |
| 1.31e-86 | FFCP PHASE1:Mm9::chr19:58804381..58804392,+#_95623124942f1e1aa240aa22e89ee361 | p@chr19:58804381..58804392, + |
| 1.31e-86 | FFCP PHASE2:Mm9::chr6:30494986..30494997,+#_95623124942f1e1aa240aa22e89ee361 | p@chr6:30494986..30494997, + |
| 1.31e-86 | FFCP PHASE1:Mm9::chr6:30494986..30494997,+#_95623124942f1e1aa240aa22e89ee361 | p@chr6:30494986..30494997, + |
| 2.27e-79 | FFCP PHASE2:Mm9::chr2:19374076..19374083,+#_9c8def3879a09329e279f785ba2f101d | p2@ENSMUST00000149577 |
| 2.27e-79 | FFCP PHASE1:Mm9::chr8:114225711..114225718,+#_9c8def3879a09329e279f785ba2f101d | p@chr8:114225711..114225718, + |
| 2.27e-79 | FFCP PHASE2:Mm9::chr9:60297477..60297496,-#_9c8def3879a09329e279f785ba2f101d | p@chr9:60297477..60297496, - |
| 2.27e-79 | FFCP PHASE1:Mm9::chr2:19410182..19410200,+#_9c8def3879a09329e279f785ba2f101d | p@chr2:19410182..19410200, + |
| 2.27e-79 | FFCP PHASE2:Mm9::chr8:114212440..114212443,-#_9c8def3879a09329e279f785ba2f101d | p@chr8:114212440..114212443, - |
| 2.27e-79 | FFCP PHASE1:Mm9::chr8:114214659..114214665,-#_9c8def3879a09329e279f785ba2f101d | p@chr8:114214659..114214665, - |
| 2.27e-79 | FFCP PHASE2:Mm9::chr15:52127064..52127100,+#_9c8def3879a09329e279f785ba2f101d | p2@Slc30a8 |
| 2.27e-79 | FFCP PHASE2:Mm9::chr8:114225711..114225718,+#_9c8def3879a09329e279f785ba2f101d | p@chr8:114225711..114225718, + |
| 2.27e-79 | FFCP PHASE2:Mm9::chr5:54068360..54068364,+#_9c8def3879a09329e279f785ba2f101d | p@chr5:54068360..54068364, + |
| 2.27e-79 | FFCP PHASE2:Mm9::chr8:114214659..114214665,-#_9c8def3879a09329e279f785ba2f101d | p@chr8:114214659..114214665, - |
| 2.27e-79 | FFCP PHASE1:Mm9::chr9:60297477..60297496,-#_9c8def3879a09329e279f785ba2f101d | p@chr9:60297477..60297496, - |
| 2.27e-79 | FFCP PHASE1:Mm9::chr5:54068360..54068364,+#_9c8def3879a09329e279f785ba2f101d | p@chr5:54068360..54068364, + |
| 2.27e-79 | FFCP PHASE1:Mm9::chr2:19374076..19374083,+#_9c8def3879a09329e279f785ba2f101d | p2@ENSMUST00000149577 |
| 2.27e-79 | FFCP PHASE1:Mm9::chr15:52127064..52127100,+#_9c8def3879a09329e279f785ba2f101d | p2@Slc30a8 |
| 2.27e-79 | FFCP PHASE1:Mm9::chr8:114212440..114212443,-#_9c8def3879a09329e279f785ba2f101d | p@chr8:114212440..114212443, - |
| 2.27e-79 | FFCP PHASE2:Mm9::chr2:19410182..19410200,+#_9c8def3879a09329e279f785ba2f101d | p@chr2:19410182..19410200, + |
| 4.35e-73 | FFCP PHASE2:Mm9::chr8:114215028..114215041,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p2@Ctrb1 |
| 4.35e-73 | FFCP PHASE1:Mm9::chr5:54098551..54098567,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p4@Cckar |
| 4.35e-73 | FFCP PHASE2:Mm9::chr5:54098551..54098567,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p4@Cckar |
| 4.35e-73 | FFCP PHASE2:Mm9::chr15:52127197..52127209,+#_497d6ea7b5f7be3b952b7920d8e1f743 | p1@Slc30a8 |
| 4.35e-73 | FFCP PHASE2:Mm9::chr19:58818563..58818576,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p@chr19:58818563..58818576, - |
| 4.35e-73 | FFCP PHASE1:Mm9::chr8:114215028..114215041,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p2@Ctrb1 |
| 4.35e-73 | FFCP PHASE2:Mm9::chr5:54097752..54097764,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p@chr5:54097752..54097764, - |
| 4.35e-73 | FFCP PHASE1:Mm9::chr19:58818563..58818576,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p@chr19:58818563..58818576, - |
| 4.35e-73 | FFCP PHASE1:Mm9::chr5:54097752..54097764,-#_497d6ea7b5f7be3b952b7920d8e1f743 | p@chr5:54097752..54097764, - |
| 4.35e-73 | FFCP PHASE1:Mm9::chr15:52127197..52127209,+#_497d6ea7b5f7be3b952b7920d8e1f743 | p1@Slc30a8 |
| 6.98e-73 | FFCP PHASE1:Mm9::chr18:34531496..34531499,-#_da602d338117dcce7924b6920a6a9919 | p@chr18:34531496..34531499, - |
| 6.98e-73 | FFCP PHASE2:Mm9::chr18:34531496..34531499,-#_da602d338117dcce7924b6920a6a9919 | p@chr18:34531496..34531499, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr8:114214342..114214354,-#_ac692940a232fbe86f9b38261904fe83 | p@chr8:114214342..114214354, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr8:114210563..114210566,+#_ac692940a232fbe86f9b38261904fe83 | p@chr8:114210563..114210566, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr16:62881258..62881265,-#_ac692940a232fbe86f9b38261904fe83 | p@chr16:62881258..62881265, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr19:58813935..58813941,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58813935..58813941, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr11:104162667..104162680,-#_ac692940a232fbe86f9b38261904fe83 | p@chr11:104162667..104162680, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr19:58812762..58812772,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812762..58812772, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr7:31243262..31243273,+#_ac692940a232fbe86f9b38261904fe83 | p6@Nphs1 |
| 3.62e-72 | FFCP PHASE1:Mm9::chr18:39522574..39522590,+#_ac692940a232fbe86f9b38261904fe83 | p@chr18:39522574..39522590, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr7:130565024..130565035,+#_ac692940a232fbe86f9b38261904fe83 | p2@Lcmt1 |
| 3.62e-72 | FFCP PHASE2:Mm9::chr7:31243262..31243273,+#_ac692940a232fbe86f9b38261904fe83 | p6@Nphs1 |
| 3.62e-72 | FFCP PHASE2:Mm9::chr11:104162667..104162680,-#_ac692940a232fbe86f9b38261904fe83 | p@chr11:104162667..104162680, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr19:58812793..58812802,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812793..58812802, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr19:58812762..58812772,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812762..58812772, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr16:62881258..62881265,-#_ac692940a232fbe86f9b38261904fe83 | p@chr16:62881258..62881265, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr15:37020111..37020125,+#_ac692940a232fbe86f9b38261904fe83 | p@chr15:37020111..37020125, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr4:141378178..141378181,-#_ac692940a232fbe86f9b38261904fe83 | p@chr4:141378178..141378181, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr5:43495214..43495226,+#_ac692940a232fbe86f9b38261904fe83 | p@chr5:43495214..43495226, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr18:39522574..39522590,+#_ac692940a232fbe86f9b38261904fe83 | p@chr18:39522574..39522590, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr18:17942879..17942880,-#_ac692940a232fbe86f9b38261904fe83 | p@chr18:17942879..17942880, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr4:141378178..141378181,-#_ac692940a232fbe86f9b38261904fe83 | p@chr4:141378178..141378181, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr19:58812844..58812855,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812844..58812855, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr19:58812793..58812802,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812793..58812802, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr8:114214342..114214354,-#_ac692940a232fbe86f9b38261904fe83 | p@chr8:114214342..114214354, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr7:130565024..130565035,+#_ac692940a232fbe86f9b38261904fe83 | p2@Lcmt1 |
| 3.62e-72 | FFCP PHASE1:Mm9::chr18:17942879..17942880,-#_ac692940a232fbe86f9b38261904fe83 | p@chr18:17942879..17942880, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr6:51270916..51270924,-#_ac692940a232fbe86f9b38261904fe83 | p@chr6:51270916..51270924, - |
| 3.62e-72 | FFCP PHASE2:Mm9::chr7:29325737..29325747,+#_ac692940a232fbe86f9b38261904fe83 | p3@Sycn |
| 3.62e-72 | FFCP PHASE2:Mm9::chr5:43495214..43495226,+#_ac692940a232fbe86f9b38261904fe83 | p@chr5:43495214..43495226, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr8:114210563..114210566,+#_ac692940a232fbe86f9b38261904fe83 | p@chr8:114210563..114210566, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr19:58813935..58813941,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58813935..58813941, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr19:58812844..58812855,+#_ac692940a232fbe86f9b38261904fe83 | p@chr19:58812844..58812855, + |
| 3.62e-72 | FFCP PHASE2:Mm9::chr6:51270916..51270924,-#_ac692940a232fbe86f9b38261904fe83 | p@chr6:51270916..51270924, - |
| 3.62e-72 | FFCP PHASE1:Mm9::chr15:37020111..37020125,+#_ac692940a232fbe86f9b38261904fe83 | p@chr15:37020111..37020125, + |
| 3.62e-72 | FFCP PHASE1:Mm9::chr7:29325737..29325747,+#_ac692940a232fbe86f9b38261904fe83 | p3@Sycn |
| 2.98e-70 | FFCP PHASE2:Mm9::chr2:19353621..19353653,-#_c284af8bbde2a585896fdd25b669032f | p1@ENSMUST00000137714 |
| 2.98e-70 | FFCP PHASE1:Mm9::chr2:28335694..28335705,+#_c284af8bbde2a585896fdd25b669032f | p@chr2:28335694..28335705, + |
| 2.98e-70 | FFCP PHASE1:Mm9::chr2:19353621..19353653,-#_c284af8bbde2a585896fdd25b669032f | p1@ENSMUST00000137714 |
| 2.98e-70 | FFCP PHASE2:Mm9::chr2:28335694..28335705,+#_c284af8bbde2a585896fdd25b669032f | p@chr2:28335694..28335705, + |
| 9.03e-68 | FFCP PHASE2:Mm9::chr19:58811529..58811552,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr19:58811529..58811552, - |
| 9.03e-68 | FFCP PHASE2:Mm9::chr8:114214598..114214609,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr8:114214598..114214609, - |
| 9.03e-68 | FFCP PHASE1:Mm9::chr8:114214263..114214282,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr8:114214263..114214282, - |
| 9.03e-68 | FFCP PHASE2:Mm9::chr3:112959660..112959680,-#_ce9a9b80965890e01a615eafa55f5268 | p1@Amy2b |
| 9.03e-68 | FFCP PHASE2:Mm9::chr8:114214263..114214282,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr8:114214263..114214282, - |
| 9.03e-68 | FFCP PHASE1:Mm9::chr3:112959660..112959680,-#_ce9a9b80965890e01a615eafa55f5268 | p1@Amy2b |
| 9.03e-68 | FFCP PHASE1:Mm9::chr19:58811529..58811552,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr19:58811529..58811552, - |
| 9.03e-68 | FFCP PHASE1:Mm9::chr8:114214598..114214609,-#_ce9a9b80965890e01a615eafa55f5268 | p@chr8:114214598..114214609, - |
| 1.05e-67 | FFCP PHASE1:Mm9::chr6:51270886..51270895,-#_cc5f11c04f62ecfd926da03b52be767a | p@chr6:51270886..51270895, - |
| 1.05e-67 | FFCP PHASE2:Mm9::chr19:58815004..58815018,+#_cc5f11c04f62ecfd926da03b52be767a | p@chr19:58815004..58815018, + |
| 1.05e-67 | FFCP PHASE2:Mm9::chr6:51270886..51270895,-#_cc5f11c04f62ecfd926da03b52be767a | p@chr6:51270886..51270895, - |
| 1.05e-67 | FFCP PHASE1:Mm9::chr19:58815004..58815018,+#_cc5f11c04f62ecfd926da03b52be767a | p@chr19:58815004..58815018, + |
| 1.21e-67 | FFCP PHASE1:Mm9::chr4:57024496..57024516,-#_79b59eab01cb34948a6e792a2a5d1b5d | p@chr4:57024496..57024516, - |
| 1.21e-67 | FFCP PHASE2:Mm9::chr16:21558663..21558681,+#_79b59eab01cb34948a6e792a2a5d1b5d | p@chr16:21558663..21558681, + |
| 1.21e-67 | FFCP PHASE2:Mm9::chr4:57024496..57024516,-#_79b59eab01cb34948a6e792a2a5d1b5d | p@chr4:57024496..57024516, - |
| 1.21e-67 | FFCP PHASE1:Mm9::chr16:21558663..21558681,+#_79b59eab01cb34948a6e792a2a5d1b5d | p@chr16:21558663..21558681, + |
| 1.62e-67 | FFCP PHASE1:Mm9::chr6:30595230..30595247,-#_713a8ba06339bece4c76464e002e3863 | p@chr6:30595230..30595247, - |
| 1.62e-67 | FFCP PHASE2:Mm9::chr6:30595230..30595247,-#_713a8ba06339bece4c76464e002e3863 | p@chr6:30595230..30595247, - |
| 4.75e-66 | FFCP PHASE2:Mm9::chr9:69950924..69950949,-#_130f0c0bb97506f8e7b37c9f3f919ab6 | p4@Fam81a |
| 4.75e-66 | FFCP PHASE1:Mm9::chr9:69950924..69950949,-#_130f0c0bb97506f8e7b37c9f3f919ab6 | p4@Fam81a |
| 5.41e-66 | FFCP PHASE1:Mm9::chr7:31243299..31243312,+#_0d8dfd15a549484001bc51a38a76e63f | p3@Nphs1 |
| 5.41e-66 | FFCP PHASE2:Mm9::chr7:31243299..31243312,+#_0d8dfd15a549484001bc51a38a76e63f | p3@Nphs1 |
| 6.69e-66 | FFCP PHASE2:Mm9::chr17:24877002..24877012,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr17:24877002..24877012, + |
| 6.69e-66 | FFCP PHASE1:Mm9::chr17:24877002..24877012,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr17:24877002..24877012, + |
| 6.69e-66 | FFCP PHASE1:Mm9::chr17:26340760..26340771,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr17:26340760..26340771, + |
| 6.69e-66 | FFCP PHASE1:Mm9::chr15:72760619..72760646,-#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr15:72760619..72760646, - |
| 6.69e-66 | FFCP PHASE2:Mm9::chr8:114211003..114211012,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr8:114211003..114211012, + |
| 6.69e-66 | FFCP PHASE2:Mm9::chr17:26340760..26340771,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr17:26340760..26340771, + |
| 6.69e-66 | FFCP PHASE2:Mm9::chr13:59680417..59680420,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr13:59680417..59680420, + |
| 6.69e-66 | FFCP PHASE1:Mm9::chr8:114211003..114211012,+#_9c3e456c31f00beb9d3f3a7b4a8a54b3 | p@chr8:114211003..114211012, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
