Novel motif:14

name:	motif14_TCNACG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0071460	cellular response to cell-matrix adhesion	4.627279e-21
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	5.061214e-17
GO:0040040	thermosensory behavior	5.819298e-17
GO:2000467	positive regulation of glycogen (starch) synthase activity	3.195229e-13
GO:0051549	positive regulation of keratinocyte migration	7.499427e-13
GO:0046628	positive regulation of insulin receptor signaling pathway	1.556750e-12
GO:0043206	fibril organization	5.001420e-12
GO:0019087	transformation of host cell by virus	1.362202e-11
GO:2000465	regulation of glycogen (starch) synthase activity	1.466355e-11
GO:0030277	maintenance of gastrointestinal epithelium	2.505679e-10
GO:0070327	thyroid hormone transport	5.569451e-10
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	7.832045e-10
GO:0033690	positive regulation of osteoblast proliferation	8.005544e-10
GO:0046687	response to chromate	8.135622e-10
GO:0033986	response to methanol	8.135622e-10
GO:0006349	regulation of gene expression by genetic imprinting	9.645900e-10
GO:0071402	cellular response to lipoprotein particle stimulus	1.074909e-9
GO:0050746	regulation of lipoprotein metabolic process	1.192170e-9
GO:0034470	ncRNA processing	1.464294e-9
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.533553e-9
GO:0045338	farnesyl diphosphate metabolic process	2.540437e-9
GO:0044240	multicellular organismal lipid catabolic process	4.320833e-9
GO:0015696	ammonium transport	4.897694e-9
GO:0034378	chylomicron assembly	6.495788e-9
GO:0071514	genetic imprinting	6.774327e-9
GO:0034633	retinol transport	8.397962e-9
GO:0016090	prenol metabolic process	1.786811e-8
GO:0035094	response to nicotine	1.885175e-8
GO:0031017	exocrine pancreas development	2.629488e-8
GO:0034014	response to triglyceride	3.137020e-8
GO:0010669	epithelial structure maintenance	4.337875e-8
GO:0034442	regulation of lipoprotein oxidation	4.607172e-8
GO:0010310	regulation of hydrogen peroxide metabolic process	4.937484e-8
GO:0090031	positive regulation of steroid hormone biosynthetic process	5.742674e-8
GO:2000273	positive regulation of receptor activity	1.464928e-7
GO:0050748	negative regulation of lipoprotein metabolic process	3.597934e-7
GO:0002536	respiratory burst involved in inflammatory response	3.780538e-7
GO:0031915	positive regulation of synaptic plasticity	4.939851e-7
GO:0035966	response to topologically incorrect protein	5.411958e-7
GO:0006006	glucose metabolic process	6.153725e-7
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	7.229317e-7
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	7.229317e-7
GO:0071322	cellular response to carbohydrate stimulus	7.591725e-7
GO:0010983	positive regulation of high-density lipoprotein particle clearance	7.658307e-7
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	7.658307e-7
GO:0008033	tRNA processing	7.794532e-7
GO:0006821	chloride transport	9.114640e-7
GO:0071333	cellular response to glucose stimulus	1.089842e-6
GO:0042396	phosphagen biosynthetic process	1.497876e-6
GO:0042373	vitamin K metabolic process	1.506509e-6
GO:0042254	ribosome biogenesis	2.087829e-6
GO:0042104	positive regulation of activated T cell proliferation	2.252503e-6
GO:0034502	protein localization to chromosome	2.253720e-6
GO:0055094	response to lipoprotein stimulus	2.364451e-6
GO:0010835	regulation of protein ADP-ribosylation	3.050540e-6
GO:0006548	histidine catabolic process	3.524975e-6
GO:0034371	chylomicron remodeling	3.967917e-6
GO:0030157	pancreatic juice secretion	4.518591e-6
GO:0002227	innate immune response in mucosa	4.616043e-6
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	4.782492e-6
GO:0055090	acylglycerol homeostasis	4.782492e-6
GO:0008078	mesodermal cell migration	4.848357e-6
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	5.067281e-6
GO:0019318	hexose metabolic process	5.811849e-6
GO:0021592	fourth ventricle development	6.100612e-6
GO:0044243	multicellular organismal catabolic process	6.106375e-6
GO:0070875	positive regulation of glycogen metabolic process	6.148114e-6
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	6.999834e-6
GO:0044319	wound healing, spreading of cells	7.615837e-6
GO:0006986	response to unfolded protein	7.630245e-6
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.128943e-5
GO:0042069	regulation of catecholamine metabolic process	1.149312e-5
GO:0034637	cellular carbohydrate biosynthetic process	1.364449e-5
GO:0001678	cellular glucose homeostasis	1.401598e-5
GO:0019048	virus-host interaction	1.476380e-5
GO:0035025	positive regulation of Rho protein signal transduction	1.553277e-5
GO:0051764	actin crosslink formation	1.620548e-5
GO:0007158	neuron cell-cell adhesion	1.735477e-5
GO:2000304	positive regulation of ceramide biosynthetic process	1.780820e-5
GO:0046314	phosphocreatine biosynthetic process	1.780820e-5
GO:0008299	isoprenoid biosynthetic process	1.865376e-5
GO:0007509	mesoderm migration involved in gastrulation	1.993601e-5
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2.003537e-5
GO:0034660	ncRNA metabolic process	2.008422e-5
GO:0055098	response to low-density lipoprotein particle stimulus	2.078663e-5
GO:0021796	cerebral cortex regionalization	2.214217e-5
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	2.214217e-5
GO:0070198	protein localization to chromosome, telomeric region	2.266657e-5
GO:0046364	monosaccharide biosynthetic process	2.281294e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.310819e-5
GO:0019319	hexose biosynthetic process	2.445596e-5
GO:0002041	intussusceptive angiogenesis	2.525509e-5
GO:0030823	regulation of cGMP metabolic process	2.808748e-5
GO:0060033	anatomical structure regression	2.815440e-5
GO:0034227	tRNA thio-modification	3.402041e-5
GO:0002098	tRNA wobble uridine modification	3.402041e-5
GO:0010509	polyamine homeostasis	3.548242e-5
GO:0045725	positive regulation of glycogen biosynthetic process	3.671986e-5
GO:0035470	positive regulation of vascular wound healing	3.743607e-5
GO:0006600	creatine metabolic process	3.776926e-5
GO:0006422	aspartyl-tRNA aminoacylation	3.784186e-5
GO:0010986	positive regulation of lipoprotein particle clearance	3.809509e-5
GO:0042574	retinal metabolic process	4.222758e-5
GO:0010288	response to lead ion	4.329087e-5
GO:0006695	cholesterol biosynthetic process	4.675488e-5
GO:0055026	negative regulation of cardiac muscle tissue development	4.771158e-5
GO:0060216	definitive hemopoiesis	4.871217e-5
GO:0007127	meiosis I	4.897300e-5
GO:0003181	atrioventricular valve morphogenesis	5.131637e-5
GO:0031668	cellular response to extracellular stimulus	5.564342e-5
GO:2000303	regulation of ceramide biosynthetic process	5.703639e-5
GO:0042662	negative regulation of mesodermal cell fate specification	5.810318e-5
GO:0051324	prophase	6.198981e-5
GO:0006547	histidine metabolic process	6.242278e-5
GO:0035814	negative regulation of renal sodium excretion	6.436105e-5
GO:0042053	regulation of dopamine metabolic process	6.920666e-5
GO:0006094	gluconeogenesis	7.573671e-5
GO:0044258	intestinal lipid catabolic process	7.832671e-5
GO:0018350	protein esterification	7.832671e-5
GO:0006096	glycolysis	8.679818e-5
GO:0042744	hydrogen peroxide catabolic process	8.831903e-5
GO:0006364	rRNA processing	9.173001e-5
GO:0032206	positive regulation of telomere maintenance	9.237495e-5
GO:0014739	positive regulation of muscle hyperplasia	1.013092e-4
GO:0061302	smooth muscle cell-matrix adhesion	1.101413e-4
GO:0060236	regulation of mitotic spindle organization	1.137599e-4
GO:0032526	response to retinoic acid	1.156083e-4
GO:0010836	negative regulation of protein ADP-ribosylation	1.206075e-4
GO:0021528	commissural neuron differentiation in spinal cord	1.206075e-4
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	1.229878e-4
GO:0071280	cellular response to copper ion	1.229878e-4
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.229878e-4
GO:0021905	forebrain-midbrain boundary formation	1.229878e-4
GO:0003322	pancreatic A cell development	1.229878e-4
GO:0035356	cellular triglyceride homeostasis	1.259140e-4
GO:0033189	response to vitamin A	1.296516e-4
GO:0006102	isocitrate metabolic process	1.342196e-4
GO:0023019	signal transduction involved in regulation of gene expression	1.384712e-4
GO:0042074	cell migration involved in gastrulation	1.416198e-4
GO:0035272	exocrine system development	1.553273e-4
GO:0061384	heart trabecular morphogenesis	1.694767e-4
GO:0035909	aorta morphogenesis	1.796058e-4
GO:0065002	intracellular protein transmembrane transport	1.805592e-4
GO:0007131	reciprocal meiotic recombination	1.873528e-4
GO:0031860	telomeric 3' overhang formation	1.900418e-4
GO:0016078	tRNA catabolic process	1.900418e-4
GO:0001682	tRNA 5'-leader removal	1.900418e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.948256e-4
GO:0050779	RNA destabilization	2.013391e-4
GO:0061072	iris morphogenesis	2.032162e-4
GO:0060465	pharynx development	2.092711e-4
GO:0016072	rRNA metabolic process	2.096205e-4
GO:0032210	regulation of telomere maintenance via telomerase	2.115080e-4
GO:0000712	resolution of meiotic recombination intermediates	2.187929e-4
GO:0006386	termination of RNA polymerase III transcription	2.196525e-4
GO:0006385	transcription elongation from RNA polymerase III promoter	2.196525e-4
GO:0048708	astrocyte differentiation	2.268527e-4
GO:0050821	protein stabilization	2.330591e-4
GO:0045907	positive regulation of vasoconstriction	2.373077e-4
GO:0005997	xylulose metabolic process	2.466659e-4
GO:0019430	removal of superoxide radicals	2.495342e-4
GO:0021678	third ventricle development	2.540473e-4
GO:0051023	regulation of immunoglobulin secretion	2.567993e-4
GO:0097045	phosphatidylserine exposure on blood platelet	2.571066e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	2.571066e-4
GO:0046006	regulation of activated T cell proliferation	2.649163e-4
GO:0031297	replication fork processing	2.653748e-4
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	2.713222e-4
GO:0032802	low-density lipoprotein particle receptor catabolic process	2.754498e-4
GO:0022600	digestive system process	2.824091e-4
GO:0021591	ventricular system development	2.868526e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.117778e-4
GO:0046886	positive regulation of hormone biosynthetic process	3.281624e-4
GO:0030225	macrophage differentiation	3.529871e-4
GO:0030825	positive regulation of cGMP metabolic process	3.623071e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	3.623071e-4
GO:0071168	protein localization to chromatin	3.836691e-4
GO:0030828	positive regulation of cGMP biosynthetic process	3.855957e-4
GO:0032425	positive regulation of mismatch repair	3.971779e-4
GO:0001578	microtubule bundle formation	4.048459e-4
GO:0060347	heart trabecula formation	4.165099e-4
GO:0021983	pituitary gland development	4.176666e-4
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	4.187887e-4
GO:0071673	positive regulation of smooth muscle cell chemotaxis	4.395280e-4
GO:0051452	intracellular pH reduction	4.574476e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	4.637080e-4
GO:0002693	positive regulation of cellular extravasation	4.684200e-4
GO:0010898	positive regulation of triglyceride catabolic process	4.853203e-4
GO:0021986	habenula development	4.903895e-4
GO:0051932	synaptic transmission, GABAergic	4.949410e-4
GO:0034241	positive regulation of macrophage fusion	4.949410e-4
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	5.052293e-4
GO:0070873	regulation of glycogen metabolic process	5.103590e-4
GO:0045940	positive regulation of steroid metabolic process	5.134075e-4
GO:0034389	lipid particle organization	5.256007e-4
GO:0030070	insulin processing	5.256007e-4
GO:0035813	regulation of renal sodium excretion	5.382401e-4
GO:0019049	evasion of host defenses by virus	5.719773e-4
GO:0051024	positive regulation of immunoglobulin secretion	5.739230e-4
GO:0071105	response to interleukin-11	5.939925e-4
GO:0090030	regulation of steroid hormone biosynthetic process	6.044505e-4
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	6.084484e-4
GO:0046165	alcohol biosynthetic process	6.127019e-4
GO:0044062	regulation of excretion	6.351199e-4
GO:0006383	transcription from RNA polymerase III promoter	6.453370e-4
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	6.457101e-4
GO:0003142	cardiogenic plate morphogenesis	6.457101e-4
GO:0070328	triglyceride homeostasis	6.620408e-4
GO:0040029	regulation of gene expression, epigenetic	6.621708e-4
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	6.625315e-4
GO:0070301	cellular response to hydrogen peroxide	6.715151e-4
GO:0090303	positive regulation of wound healing	6.915248e-4
GO:0035967	cellular response to topologically incorrect protein	7.265376e-4
GO:0043985	histone H4-R3 methylation	7.363250e-4
GO:0014738	regulation of muscle hyperplasia	7.363250e-4
GO:0042135	neurotransmitter catabolic process	7.367028e-4
GO:0021978	telencephalon regionalization	7.403521e-4
GO:0032202	telomere assembly	7.420311e-4
GO:0072337	modified amino acid transport	7.605423e-4
GO:0060413	atrial septum morphogenesis	7.611409e-4
GO:0030826	regulation of cGMP biosynthetic process	7.880622e-4
GO:0035845	photoreceptor cell outer segment organization	8.797407e-4
GO:0035499	carnosine biosynthetic process	8.797407e-4
GO:0051303	establishment of chromosome localization	8.995418e-4
GO:0033566	gamma-tubulin complex localization	9.287395e-4
GO:0006260	DNA replication	9.329503e-4
GO:0030198	extracellular matrix organization	9.401490e-4
GO:0045132	meiotic chromosome segregation	9.443692e-4
GO:0006447	regulation of translational initiation by iron	9.765478e-4
GO:0016233	telomere capping	9.765478e-4
GO:0045851	pH reduction	1.007755e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	1.013438e-3
GO:0006412	translation	1.020650e-3
GO:0006007	glucose catabolic process	1.031092e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	1.078140e-3
GO:0045994	positive regulation of translational initiation by iron	1.081469e-3
GO:0051006	positive regulation of lipoprotein lipase activity	1.081469e-3
GO:0002037	negative regulation of L-glutamate transport	1.081469e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.082587e-3
GO:0044236	multicellular organismal metabolic process	1.094819e-3
GO:0000022	mitotic spindle elongation	1.141691e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.142616e-3
GO:0007052	mitotic spindle organization	1.150127e-3
GO:0006081	cellular aldehyde metabolic process	1.169159e-3
GO:0034629	cellular protein complex localization	1.188629e-3
GO:0003283	atrial septum development	1.193429e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	1.242584e-3
GO:0060828	regulation of canonical Wnt receptor signaling pathway	1.245639e-3
GO:0010624	regulation of Schwann cell proliferation	1.257396e-3
GO:0010715	regulation of extracellular matrix disassembly	1.259340e-3
GO:0015936	coenzyme A metabolic process	1.261022e-3
GO:0042552	myelination	1.303944e-3
GO:0007589	body fluid secretion	1.313548e-3
GO:0006458	'de novo' protein folding	1.361794e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.367080e-3
GO:0051310	metaphase plate congression	1.400333e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.403647e-3
GO:0031848	protection from non-homologous end joining at telomere	1.412700e-3
GO:0035313	wound healing, spreading of epidermal cells	1.423852e-3
GO:0030221	basophil differentiation	1.446688e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.446729e-3
GO:0003278	apoptosis involved in heart morphogenesis	1.461810e-3
GO:0071733	transcriptional activation by promoter-enhancer looping	1.522939e-3
GO:0010724	regulation of definitive erythrocyte differentiation	1.522939e-3
GO:0032682	negative regulation of chemokine production	1.538879e-3
GO:0031284	positive regulation of guanylate cyclase activity	1.538879e-3
GO:0060712	spongiotrophoblast layer development	1.557151e-3
GO:0010002	cardioblast differentiation	1.640800e-3
GO:0007586	digestion	1.643486e-3
GO:0005996	monosaccharide metabolic process	1.690000e-3
GO:0006768	biotin metabolic process	1.694621e-3
GO:0048205	COPI coating of Golgi vesicle	1.701617e-3
GO:0046730	induction of host immune response by virus	1.718235e-3
GO:0043587	tongue morphogenesis	1.768274e-3
GO:0005999	xylulose biosynthetic process	1.798670e-3
GO:0031442	positive regulation of mRNA 3'-end processing	1.858990e-3
GO:0002678	positive regulation of chronic inflammatory response	1.858990e-3
GO:0006228	UTP biosynthetic process	1.878531e-3
GO:0045040	protein import into mitochondrial outer membrane	1.878531e-3
GO:0006183	GTP biosynthetic process	1.878531e-3
GO:0006165	nucleoside diphosphate phosphorylation	1.878531e-3
GO:0006457	protein folding	1.904413e-3
GO:0033169	histone H3-K9 demethylation	1.934128e-3
GO:0044003	modification by symbiont of host morphology or physiology	1.954660e-3
GO:0034969	histone arginine methylation	1.958681e-3
GO:0051302	regulation of cell division	1.986111e-3
GO:0010984	regulation of lipoprotein particle clearance	1.986756e-3
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	2.042197e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.044944e-3
GO:0010896	regulation of triglyceride catabolic process	2.046545e-3
GO:0006391	transcription initiation from mitochondrial promoter	2.052026e-3
GO:0070212	protein poly-ADP-ribosylation	2.071530e-3
GO:0005979	regulation of glycogen biosynthetic process	2.078290e-3
GO:0009589	detection of UV	2.103489e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	2.103489e-3
GO:0010477	response to sulfur dioxide	2.103489e-3
GO:0002457	T cell antigen processing and presentation	2.103489e-3
GO:0000088	mitotic prophase	2.103489e-3
GO:0032233	positive regulation of actin filament bundle assembly	2.134068e-3
GO:0061014	positive regulation of mRNA catabolic process	2.155150e-3
GO:0000303	response to superoxide	2.170662e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	2.173748e-3
GO:0071529	cementum mineralization	2.189564e-3
GO:0046889	positive regulation of lipid biosynthetic process	2.197059e-3
GO:0032224	positive regulation of synaptic transmission, cholinergic	2.258686e-3
GO:0022613	ribonucleoprotein complex biogenesis	2.281882e-3
GO:0035910	ascending aorta morphogenesis	2.325178e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	2.325178e-3
GO:0060042	retina morphogenesis in camera-type eye	2.335157e-3
GO:0007128	meiotic prophase I	2.341379e-3
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	2.344647e-3
GO:0042149	cellular response to glucose starvation	2.363677e-3
GO:0034375	high-density lipoprotein particle remodeling	2.367621e-3
GO:0051013	microtubule severing	2.431381e-3
GO:0032790	ribosome disassembly	2.431381e-3
GO:0046108	uridine metabolic process	2.431381e-3
GO:0051781	positive regulation of cell division	2.444531e-3
GO:0071218	cellular response to misfolded protein	2.507412e-3
GO:0010469	regulation of receptor activity	2.513291e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	2.539717e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	2.583052e-3
GO:0046549	retinal cone cell development	2.586516e-3
GO:0051084	'de novo' posttranslational protein folding	2.603638e-3
GO:0014912	negative regulation of smooth muscle cell migration	2.673012e-3
GO:0021517	ventral spinal cord development	2.692235e-3
GO:0010893	positive regulation of steroid biosynthetic process	2.704180e-3
GO:0035195	gene silencing by miRNA	2.793374e-3
GO:0021670	lateral ventricle development	2.795192e-3
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	2.802977e-3
GO:0072086	specification of loop of Henle identity	2.802977e-3
GO:0006651	diacylglycerol biosynthetic process	2.832659e-3
GO:0015698	inorganic anion transport	2.910801e-3
GO:0019883	antigen processing and presentation of endogenous antigen	2.914690e-3
GO:0031053	primary miRNA processing	2.967243e-3
GO:0035020	regulation of Rac protein signal transduction	2.982568e-3
GO:0070208	protein heterotrimerization	3.050475e-3
GO:0043243	positive regulation of protein complex disassembly	3.078296e-3
GO:0016446	somatic hypermutation of immunoglobulin genes	3.094026e-3
GO:0030836	positive regulation of actin filament depolymerization	3.094026e-3
GO:0008635	activation of caspase activity by cytochrome c	3.094026e-3
GO:0000089	mitotic metaphase	3.094026e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	3.115631e-3
GO:0031647	regulation of protein stability	3.126225e-3
GO:0010907	positive regulation of glucose metabolic process	3.161998e-3
GO:2000778	positive regulation of interleukin-6 secretion	3.230646e-3
GO:0048013	ephrin receptor signaling pathway	3.279581e-3
GO:0060976	coronary vasculature development	3.318948e-3
GO:0015761	mannose transport	3.325874e-3
GO:0031081	nuclear pore distribution	3.325874e-3
GO:0009451	RNA modification	3.409789e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	3.447822e-3
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	3.482244e-3
GO:0035732	nitric oxide storage	3.482244e-3
GO:0035726	common myeloid progenitor cell proliferation	3.482244e-3
GO:0031627	telomeric loop formation	3.482244e-3
GO:0006261	DNA-dependent DNA replication	3.515729e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	3.520225e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	3.520225e-3
GO:0030431	sleep	3.534420e-3
GO:0001522	pseudouridine synthesis	3.585404e-3
GO:0019059	initiation of viral infection	3.683795e-3
GO:0060999	positive regulation of dendritic spine development	3.701902e-3
GO:0045104	intermediate filament cytoskeleton organization	3.718932e-3
GO:0034614	cellular response to reactive oxygen species	3.827154e-3
GO:0072593	reactive oxygen species metabolic process	3.833137e-3
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	3.856551e-3
GO:0035635	entry of bacterium into host cell	3.856551e-3
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	3.856551e-3
GO:0003170	heart valve development	3.870726e-3
GO:0060290	transdifferentiation	3.891159e-3
GO:0008366	axon ensheathment	3.892675e-3
GO:0042593	glucose homeostasis	3.938853e-3
GO:0032352	positive regulation of hormone metabolic process	3.956006e-3
GO:0051321	meiotic cell cycle	3.991238e-3
GO:0060563	neuroepithelial cell differentiation	4.055174e-3
GO:0048194	Golgi vesicle budding	4.090092e-3
GO:0007088	regulation of mitosis	4.118031e-3
GO:0003206	cardiac chamber morphogenesis	4.130227e-3
GO:0006772	thiamine metabolic process	4.169036e-3
GO:0044275	cellular carbohydrate catabolic process	4.193619e-3
GO:2000188	regulation of cholesterol homeostasis	4.225387e-3
GO:0046939	nucleotide phosphorylation	4.237362e-3
GO:0016126	sterol biosynthetic process	4.285255e-3
GO:0040009	regulation of growth rate	4.394885e-3
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	4.394885e-3
GO:0035022	positive regulation of Rac protein signal transduction	4.417757e-3
GO:0033688	regulation of osteoblast proliferation	4.458641e-3
GO:0045820	negative regulation of glycolysis	4.481569e-3
GO:0003289	atrial septum primum morphogenesis	4.481569e-3
GO:0030497	fatty acid elongation	4.495844e-3
GO:0007183	SMAD protein complex assembly	4.504547e-3
GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	4.511605e-3
GO:0042109	lymphotoxin A biosynthetic process	4.511605e-3
GO:0034372	very-low-density lipoprotein particle remodeling	4.529290e-3
GO:0021536	diencephalon development	4.610166e-3
GO:0014910	regulation of smooth muscle cell migration	4.690206e-3
GO:0042572	retinol metabolic process	4.736930e-3
GO:0022011	myelination in peripheral nervous system	4.736930e-3
GO:0042761	very long-chain fatty acid biosynthetic process	4.764650e-3
GO:0019367	fatty acid elongation, saturated fatty acid	4.780083e-3
GO:0006564	L-serine biosynthetic process	4.815961e-3
GO:0051496	positive regulation of stress fiber assembly	4.917515e-3
GO:0033108	mitochondrial respiratory chain complex assembly	4.954932e-3
GO:0001754	eye photoreceptor cell differentiation	4.955735e-3
GO:2000002	negative regulation of DNA damage checkpoint	5.089437e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	5.089437e-3
GO:0021551	central nervous system morphogenesis	5.089437e-3
GO:0021588	cerebellum formation	5.089437e-3
GO:0060022	hard palate development	5.137951e-3
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	5.137951e-3
GO:0050686	negative regulation of mRNA processing	5.142363e-3
GO:0010936	negative regulation of macrophage cytokine production	5.142363e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5.142363e-3
GO:0006720	isoprenoid metabolic process	5.187787e-3
GO:0032212	positive regulation of telomere maintenance via telomerase	5.266187e-3
GO:0051798	positive regulation of hair follicle development	5.267165e-3
GO:0032075	positive regulation of nuclease activity	5.297798e-3
GO:0014707	branchiomeric skeletal muscle development	5.299846e-3
GO:0032964	collagen biosynthetic process	5.358168e-3
GO:0043255	regulation of carbohydrate biosynthetic process	5.381932e-3
GO:0006270	DNA-dependent DNA replication initiation	5.411155e-3
GO:0060904	regulation of protein folding in endoplasmic reticulum	5.434122e-3
GO:0021589	cerebellum structural organization	5.434122e-3
GO:0000492	box C/D snoRNP assembly	5.537304e-3
GO:0000305	response to oxygen radical	5.543263e-3
GO:2000380	regulation of mesoderm development	5.549702e-3
GO:0007023	post-chaperonin tubulin folding pathway	5.693255e-3
GO:0046548	retinal rod cell development	5.728599e-3
GO:0000072	M phase specific microtubule process	5.814636e-3
GO:0060575	intestinal epithelial cell differentiation	6.046312e-3
GO:0033627	cell adhesion mediated by integrin	6.046312e-3
GO:0016082	synaptic vesicle priming	6.076033e-3
GO:0051156	glucose 6-phosphate metabolic process	6.109454e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	6.109454e-3
GO:0006399	tRNA metabolic process	6.116803e-3
GO:0035634	response to stilbenoid	6.180629e-3
GO:0032916	positive regulation of transforming growth factor beta3 production	6.392441e-3
GO:0006396	RNA processing	6.397872e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	6.407986e-3
GO:0021854	hypothalamus development	6.465049e-3
GO:0003179	heart valve morphogenesis	6.595315e-3
GO:0060411	cardiac septum morphogenesis	6.688395e-3
GO:0071474	cellular hyperosmotic response	6.714993e-3
GO:0048593	camera-type eye morphogenesis	6.736257e-3
GO:0032793	positive regulation of CREB transcription factor activity	6.799412e-3
GO:0072268	pattern specification involved in metanephros development	6.901198e-3
GO:0018206	peptidyl-methionine modification	6.901198e-3
GO:0022415	viral reproductive process	6.958198e-3
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.968383e-3
GO:0042450	arginine biosynthetic process via ornithine	6.968383e-3
GO:0021771	lateral geniculate nucleus development	6.968383e-3
GO:0042661	regulation of mesodermal cell fate specification	6.979384e-3
GO:0033235	positive regulation of protein sumoylation	6.997602e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	7.068632e-3
GO:0006241	CTP biosynthetic process	7.074373e-3
GO:0043467	regulation of generation of precursor metabolites and energy	7.113389e-3
GO:0007217	tachykinin receptor signaling pathway	7.120166e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	7.155416e-3
GO:0007006	mitochondrial membrane organization	7.188943e-3
GO:0019478	D-amino acid catabolic process	7.193329e-3
GO:0009107	lipoate biosynthetic process	7.193329e-3
GO:0071277	cellular response to calcium ion	7.242252e-3
GO:0002663	positive regulation of B cell tolerance induction	7.248479e-3
GO:0033484	nitric oxide homeostasis	7.300835e-3
GO:0046339	diacylglycerol metabolic process	7.366378e-3
GO:0002089	lens morphogenesis in camera-type eye	7.394038e-3
GO:0051323	metaphase	7.470522e-3
GO:0019320	hexose catabolic process	7.498423e-3
GO:0021778	oligodendrocyte cell fate specification	7.500689e-3
GO:0001579	medium-chain fatty acid transport	7.726596e-3
GO:2000824	negative regulation of androgen receptor activity	7.726596e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	7.736425e-3
GO:0034508	centromere complex assembly	7.762075e-3
GO:0006984	ER-nucleus signaling pathway	7.788210e-3
GO:0071875	adrenergic receptor signaling pathway	7.818664e-3
GO:0003183	mitral valve morphogenesis	7.818664e-3
GO:0051956	negative regulation of amino acid transport	7.882097e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	7.891767e-3
GO:0007126	meiosis	7.903618e-3
GO:0009584	detection of visible light	7.906461e-3
GO:0032071	regulation of endodeoxyribonuclease activity	8.079268e-3
GO:0019682	glyceraldehyde-3-phosphate metabolic process	8.079268e-3
GO:0042942	D-serine transport	8.079268e-3
GO:0002508	central tolerance induction	8.079268e-3
GO:0002897	positive regulation of central B cell tolerance induction	8.079268e-3
GO:0016598	protein arginylation	8.079268e-3
GO:0016032	viral reproduction	8.079692e-3
GO:0035928	rRNA import into mitochondrion	8.128059e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	8.170868e-3
GO:0042226	interleukin-6 biosynthetic process	8.193328e-3
GO:0072668	tubulin complex biogenesis	8.243539e-3
GO:0046833	positive regulation of RNA export from nucleus	8.347053e-3
GO:0051882	mitochondrial depolarization	8.347053e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	8.347053e-3
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	8.347053e-3
GO:0016142	O-glycoside catabolic process	8.347053e-3
GO:0031120	snRNA pseudouridine synthesis	8.347053e-3
GO:0042424	catecholamine catabolic process	8.394971e-3
GO:0072081	specification of nephron tubule identity	8.508288e-3
GO:0035419	activation of MAPK activity involved in innate immune response	8.513784e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042254	ribosome biogenesis	2.447309e-12
GO:0016072	rRNA metabolic process	1.144581e-11
GO:0048668	collateral sprouting	6.312683e-11
GO:0006364	rRNA processing	1.100909e-10
GO:0034470	ncRNA processing	1.657762e-10
GO:0071843	cellular component biogenesis at cellular level	1.875806e-10
GO:0015986	ATP synthesis coupled proton transport	3.180184e-10
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	3.595743e-10
GO:0022613	ribonucleoprotein complex biogenesis	5.794579e-10
GO:0034660	ncRNA metabolic process	1.674830e-9
GO:0006507	GPI anchor release	2.117783e-9
GO:0030968	endoplasmic reticulum unfolded protein response	1.624407e-8
GO:0006396	RNA processing	1.628775e-8
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.723341e-8
GO:0035967	cellular response to topologically incorrect protein	5.179993e-8
GO:0034442	regulation of lipoprotein oxidation	5.393159e-8
GO:0007052	mitotic spindle organization	7.817442e-8
GO:0043623	cellular protein complex assembly	9.461730e-8
GO:0007632	visual behavior	1.006028e-7
GO:0006308	DNA catabolic process	1.118401e-7
GO:0006139	nucleobase-containing compound metabolic process	1.127954e-7
GO:0090304	nucleic acid metabolic process	1.255177e-7
GO:0055090	acylglycerol homeostasis	1.699931e-7
GO:0006986	response to unfolded protein	1.878132e-7
GO:0008542	visual learning	1.931304e-7
GO:0090307	spindle assembly involved in mitosis	2.301198e-7
GO:0007051	spindle organization	2.460395e-7
GO:0006306	DNA methylation	2.768244e-7
GO:0045040	protein import into mitochondrial outer membrane	2.808565e-7
GO:0034641	cellular nitrogen compound metabolic process	3.330278e-7
GO:0051258	protein polymerization	4.201062e-7
GO:0048669	collateral sprouting in absence of injury	4.737352e-7
GO:0007618	mating	5.100265e-7
GO:0010312	detoxification of zinc ion	5.201544e-7
GO:0010467	gene expression	6.556735e-7
GO:0006982	response to lipid hydroperoxide	7.777934e-7
GO:0030202	heparin metabolic process	8.512272e-7
GO:0050748	negative regulation of lipoprotein metabolic process	1.026524e-6
GO:0010936	negative regulation of macrophage cytokine production	1.145346e-6
GO:0002092	positive regulation of receptor internalization	1.145346e-6
GO:0060051	negative regulation of protein glycosylation	1.237513e-6
GO:0016074	snoRNA metabolic process	1.380902e-6
GO:0006807	nitrogen compound metabolic process	1.472439e-6
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.545396e-6
GO:0055070	copper ion homeostasis	1.769050e-6
GO:0044237	cellular metabolic process	1.850603e-6
GO:0050689	negative regulation of defense response to virus by host	1.938237e-6
GO:0010898	positive regulation of triglyceride catabolic process	2.166318e-6
GO:0000085	G2 phase of mitotic cell cycle	2.185834e-6
GO:0009817	defense response to fungus, incompatible interaction	2.708449e-6
GO:0006878	cellular copper ion homeostasis	3.179806e-6
GO:0019098	reproductive behavior	4.242112e-6
GO:0061088	regulation of sequestering of zinc ion	4.333201e-6
GO:0060049	regulation of protein glycosylation	4.333201e-6
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	4.593215e-6
GO:0032465	regulation of cytokinesis	4.817813e-6
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	5.169046e-6
GO:0017196	N-terminal peptidyl-methionine acetylation	5.169046e-6
GO:0044260	cellular macromolecule metabolic process	5.373610e-6
GO:0034976	response to endoplasmic reticulum stress	5.383829e-6
GO:0045626	negative regulation of T-helper 1 cell differentiation	5.549383e-6
GO:0035966	response to topologically incorrect protein	6.406953e-6
GO:0006206	pyrimidine base metabolic process	6.485011e-6
GO:0007617	mating behavior	6.792947e-6
GO:0035092	sperm chromatin condensation	7.739052e-6
GO:0006412	translation	1.048904e-5
GO:0006084	acetyl-CoA metabolic process	1.049304e-5
GO:0022007	convergent extension involved in neural plate elongation	1.066269e-5
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.066269e-5
GO:0016070	RNA metabolic process	1.088023e-5
GO:0021794	thalamus development	1.091038e-5
GO:0006984	ER-nucleus signaling pathway	1.219652e-5
GO:2000117	negative regulation of cysteine-type endopeptidase activity	1.288146e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.358469e-5
GO:0040029	regulation of gene expression, epigenetic	1.502384e-5
GO:0032467	positive regulation of cytokinesis	1.619204e-5
GO:0051124	synaptic growth at neuromuscular junction	1.636480e-5
GO:0051225	spindle assembly	1.680151e-5
GO:0006561	proline biosynthetic process	1.715364e-5
GO:0043932	ossification involved in bone remodeling	1.715364e-5
GO:0001829	trophectodermal cell differentiation	1.781061e-5
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.056263e-5
GO:0030970	retrograde protein transport, ER to cytosol	2.205605e-5
GO:0050746	regulation of lipoprotein metabolic process	2.398052e-5
GO:0007017	microtubule-based process	2.539824e-5
GO:0007183	SMAD protein complex assembly	2.771626e-5
GO:0006818	hydrogen transport	2.787812e-5
GO:0002227	innate immune response in mucosa	2.876986e-5
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.907482e-5
GO:0090285	negative regulation of protein glycosylation in Golgi	3.016540e-5
GO:0009451	RNA modification	3.116379e-5
GO:0060124	positive regulation of growth hormone secretion	3.320435e-5
GO:0015992	proton transport	3.342894e-5
GO:2000781	positive regulation of double-strand break repair	3.413709e-5
GO:0016140	O-glycoside metabolic process	3.413709e-5
GO:0001522	pseudouridine synthesis	3.466559e-5
GO:0019049	evasion of host defenses by virus	3.591806e-5
GO:0046958	nonassociative learning	3.879783e-5
GO:0006754	ATP biosynthetic process	4.039562e-5
GO:0019430	removal of superoxide radicals	4.052259e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	4.142411e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	4.142411e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	4.142411e-5
GO:0032707	negative regulation of interleukin-23 production	4.142411e-5
GO:0016142	O-glycoside catabolic process	4.142411e-5
GO:0045617	negative regulation of keratinocyte differentiation	4.186116e-5
GO:0045357	regulation of interferon-beta biosynthetic process	4.991900e-5
GO:0002513	tolerance induction to self antigen	5.208642e-5
GO:0001824	blastocyst development	5.620283e-5
GO:0070194	synaptonemal complex disassembly	6.060861e-5
GO:0042417	dopamine metabolic process	6.313565e-5
GO:0002537	nitric oxide production involved in inflammatory response	6.684086e-5
GO:0001839	neural plate morphogenesis	6.883287e-5
GO:0006505	GPI anchor metabolic process	7.399108e-5
GO:0060390	regulation of SMAD protein import into nucleus	7.604265e-5
GO:0032874	positive regulation of stress-activated MAPK cascade	7.785649e-5
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	7.879642e-5
GO:0032648	regulation of interferon-beta production	7.880635e-5
GO:0000305	response to oxygen radical	7.897405e-5
GO:0060391	positive regulation of SMAD protein import into nucleus	7.914431e-5
GO:0031396	regulation of protein ubiquitination	8.285646e-5
GO:0000738	DNA catabolic process, exonucleolytic	8.604905e-5
GO:0045844	positive regulation of striated muscle tissue development	9.137432e-5
GO:0021860	pyramidal neuron development	9.434160e-5
GO:0050765	negative regulation of phagocytosis	9.600613e-5
GO:0006465	signal peptide processing	9.655932e-5
GO:0051302	regulation of cell division	1.173339e-4
GO:0015761	mannose transport	1.210412e-4
GO:0002483	antigen processing and presentation of endogenous peptide antigen	1.239024e-4
GO:0006259	DNA metabolic process	1.261669e-4
GO:0006304	DNA modification	1.279364e-4
GO:0018364	peptidyl-glutamine methylation	1.377070e-4
GO:0000226	microtubule cytoskeleton organization	1.401276e-4
GO:0000103	sulfate assimilation	1.407862e-4
GO:0051131	chaperone-mediated protein complex assembly	1.457544e-4
GO:0010561	negative regulation of glycoprotein biosynthetic process	1.457544e-4
GO:0032218	riboflavin transport	1.474240e-4
GO:0033194	response to hydroperoxide	1.564241e-4
GO:0032606	type I interferon production	1.578539e-4
GO:0034619	cellular chaperone-mediated protein complex assembly	1.690233e-4
GO:0033135	regulation of peptidyl-serine phosphorylation	1.702655e-4
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1.726566e-4
GO:0007008	outer mitochondrial membrane organization	1.751635e-4
GO:0032967	positive regulation of collagen biosynthetic process	1.814057e-4
GO:0031663	lipopolysaccharide-mediated signaling pathway	1.882757e-4
GO:0016322	neuron remodeling	1.963768e-4
GO:0032479	regulation of type I interferon production	2.002018e-4
GO:0018206	peptidyl-methionine modification	2.008349e-4
GO:0046491	L-methylmalonyl-CoA metabolic process	2.210277e-4
GO:0045090	retroviral genome replication	2.210277e-4
GO:0001682	tRNA 5'-leader removal	2.210277e-4
GO:0016078	tRNA catabolic process	2.210277e-4
GO:0035372	protein localization to microtubule	2.212832e-4
GO:0001555	oocyte growth	2.391762e-4
GO:0016926	protein desumoylation	2.404777e-4
GO:0006099	tricarboxylic acid cycle	2.488003e-4
GO:0008535	respiratory chain complex IV assembly	2.510412e-4
GO:0006085	acetyl-CoA biosynthetic process	2.510412e-4
GO:0032727	positive regulation of interferon-alpha production	2.531810e-4
GO:0048599	oocyte development	2.543975e-4
GO:0032259	methylation	2.576568e-4
GO:0050668	positive regulation of homocysteine metabolic process	2.606118e-4
GO:0045963	negative regulation of dopamine metabolic process	2.606118e-4
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	2.606118e-4
GO:0022900	electron transport chain	2.714024e-4
GO:0030201	heparan sulfate proteoglycan metabolic process	2.857758e-4
GO:0033138	positive regulation of peptidyl-serine phosphorylation	2.910430e-4
GO:0090208	positive regulation of triglyceride metabolic process	3.098424e-4
GO:0043154	negative regulation of caspase activity	3.102850e-4
GO:0034622	cellular macromolecular complex assembly	3.103960e-4
GO:0080164	regulation of nitric oxide metabolic process	3.117823e-4
GO:0051932	synaptic transmission, GABAergic	3.117823e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	3.117823e-4
GO:0018158	protein oxidation	3.130453e-4
GO:0006413	translational initiation	3.145536e-4
GO:0007614	short-term memory	3.147486e-4
GO:0006560	proline metabolic process	3.362402e-4
GO:0070935	3'-UTR-mediated mRNA stabilization	3.365773e-4
GO:0001825	blastocyst formation	3.367148e-4
GO:0007528	neuromuscular junction development	3.373523e-4
GO:0009994	oocyte differentiation	3.394722e-4
GO:0046512	sphingosine biosynthetic process	3.396098e-4
GO:0030857	negative regulation of epithelial cell differentiation	3.548113e-4
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	3.596229e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	3.633031e-4
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	3.642963e-4
GO:0001840	neural plate development	3.680383e-4
GO:0034614	cellular response to reactive oxygen species	3.711966e-4
GO:0033211	adiponectin-mediated signaling pathway	3.787848e-4
GO:0016073	snRNA metabolic process	3.787848e-4
GO:0051006	positive regulation of lipoprotein lipase activity	3.839824e-4
GO:0060364	frontal suture morphogenesis	3.870083e-4
GO:0071777	positive regulation of cell cycle cytokinesis	3.930193e-4
GO:0051781	positive regulation of cell division	3.996401e-4
GO:0061034	olfactory bulb mitral cell layer development	4.097367e-4
GO:0031536	positive regulation of exit from mitosis	4.097367e-4
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	4.275137e-4
GO:0045351	type I interferon biosynthetic process	4.705666e-4
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	4.705666e-4
GO:0021670	lateral ventricle development	4.758079e-4
GO:0009201	ribonucleoside triphosphate biosynthetic process	4.785461e-4
GO:0006383	transcription from RNA polymerase III promoter	5.113570e-4
GO:0034621	cellular macromolecular complex subunit organization	5.289667e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.398961e-4
GO:0008306	associative learning	5.830952e-4
GO:0010896	regulation of triglyceride catabolic process	5.840898e-4
GO:0052200	response to host defenses	5.848878e-4
GO:0030262	apoptotic nuclear change	5.933474e-4
GO:0021695	cerebellar cortex development	5.991234e-4
GO:0008033	tRNA processing	6.123277e-4
GO:0048643	positive regulation of skeletal muscle tissue development	6.299511e-4
GO:0007519	skeletal muscle tissue development	6.300138e-4
GO:0060676	ureteric bud formation	6.443092e-4
GO:0021592	fourth ventricle development	6.622924e-4
GO:0035066	positive regulation of histone acetylation	6.696215e-4
GO:0048741	skeletal muscle fiber development	6.775732e-4
GO:0032853	positive regulation of Ran GTPase activity	6.882543e-4
GO:0071169	establishment of protein localization to chromatin	6.882543e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	6.882543e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	6.954192e-4
GO:0034394	protein localization at cell surface	7.044790e-4
GO:0043414	macromolecule methylation	7.097353e-4
GO:0006868	glutamine transport	7.188029e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	7.188029e-4
GO:0032922	circadian regulation of gene expression	7.215666e-4
GO:0021591	ventricular system development	7.271816e-4
GO:0045746	negative regulation of Notch signaling pathway	7.489043e-4
GO:0048627	myoblast development	7.685122e-4
GO:0021539	subthalamus development	7.685122e-4
GO:0046836	glycolipid transport	7.685122e-4
GO:0009145	purine nucleoside triphosphate biosynthetic process	8.049426e-4
GO:0007517	muscle organ development	8.280876e-4
GO:0006670	sphingosine metabolic process	8.287622e-4
GO:0060056	mammary gland involution	8.299331e-4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	8.309290e-4
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	8.379554e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	8.723359e-4
GO:0018200	peptidyl-glutamic acid modification	8.830173e-4
GO:0031398	positive regulation of protein ubiquitination	8.856918e-4
GO:0007612	learning	9.311027e-4
GO:0042559	pteridine-containing compound biosynthetic process	9.386344e-4
GO:0014707	branchiomeric skeletal muscle development	9.614300e-4
GO:0060538	skeletal muscle organ development	9.798762e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.022991e-3
GO:0031058	positive regulation of histone modification	1.025780e-3
GO:0046356	acetyl-CoA catabolic process	1.030202e-3
GO:0046755	non-lytic virus budding	1.062861e-3
GO:0006391	transcription initiation from mitochondrial promoter	1.062861e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.082332e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	1.142856e-3
GO:0016998	cell wall macromolecule catabolic process	1.154458e-3
GO:0048477	oogenesis	1.156553e-3
GO:0045578	negative regulation of B cell differentiation	1.210044e-3
GO:0071477	cellular hypotonic salinity response	1.222654e-3
GO:0035520	monoubiquitinated protein deubiquitination	1.222654e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	1.265253e-3
GO:0032872	regulation of stress-activated MAPK cascade	1.302454e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	1.344404e-3
GO:0001975	response to amphetamine	1.362107e-3
GO:0000303	response to superoxide	1.385744e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.393215e-3
GO:0071624	positive regulation of granulocyte chemotaxis	1.393215e-3
GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA	1.393215e-3
GO:0018872	arsonoacetate metabolic process	1.393215e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.394074e-3
GO:0001835	blastocyst hatching	1.440256e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	1.458580e-3
GO:0032119	sequestering of zinc ion	1.477790e-3
GO:0006399	tRNA metabolic process	1.548539e-3
GO:0010717	regulation of epithelial to mesenchymal transition	1.554541e-3
GO:0045066	regulatory T cell differentiation	1.565478e-3
GO:0009152	purine ribonucleotide biosynthetic process	1.578725e-3
GO:0048535	lymph node development	1.622314e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	1.629453e-3
GO:0006207	'de novo' pyrimidine base biosynthetic process	1.629849e-3
GO:0042840	D-glucuronate catabolic process	1.633609e-3
GO:0019348	dolichol metabolic process	1.660213e-3
GO:0032965	regulation of collagen biosynthetic process	1.685757e-3
GO:0008063	Toll signaling pathway	1.764828e-3
GO:0006921	cellular component disassembly involved in apoptosis	1.783691e-3
GO:0032845	negative regulation of homeostatic process	1.804490e-3
GO:0045046	protein import into peroxisome membrane	1.806287e-3
GO:0006680	glucosylceramide catabolic process	1.806287e-3
GO:0009142	nucleoside triphosphate biosynthetic process	1.825556e-3
GO:0061072	iris morphogenesis	1.855160e-3
GO:0042628	mating plug formation	1.855160e-3
GO:0016557	peroxisome membrane biogenesis	1.867074e-3
GO:0014842	regulation of satellite cell proliferation	1.867074e-3
GO:0035235	ionotropic glutamate receptor signaling pathway	1.891422e-3
GO:0006730	one-carbon metabolic process	1.894291e-3
GO:0060716	labyrinthine layer blood vessel development	1.905744e-3
GO:0032660	regulation of interleukin-17 production	1.956912e-3
GO:0009112	nucleobase metabolic process	1.976351e-3
GO:0006493	protein O-linked glycosylation	2.032216e-3
GO:0042420	dopamine catabolic process	2.215221e-3
GO:0048747	muscle fiber development	2.221297e-3
GO:0045605	negative regulation of epidermal cell differentiation	2.234851e-3
GO:0097039	protein linear polyubiquitination	2.277768e-3
GO:0071476	cellular hypotonic response	2.277768e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.277768e-3
GO:0033629	negative regulation of cell adhesion mediated by integrin	2.277768e-3
GO:0051568	histone H3-K4 methylation	2.316459e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	2.346525e-3
GO:0000244	assembly of spliceosomal tri-snRNP	2.346525e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	2.346525e-3
GO:0031100	organ regeneration	2.378255e-3
GO:0060674	placenta blood vessel development	2.389182e-3
GO:0060349	bone morphogenesis	2.404464e-3
GO:0032469	endoplasmic reticulum calcium ion homeostasis	2.420682e-3
GO:0051135	positive regulation of NK T cell activation	2.449811e-3
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	2.468069e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	2.552103e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	2.555444e-3
GO:0060363	cranial suture morphogenesis	2.561089e-3
GO:0051340	regulation of ligase activity	2.574737e-3
GO:0007320	insemination	2.600167e-3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	2.621246e-3
GO:0001544	initiation of primordial ovarian follicle growth	2.751859e-3
GO:0043217	myelin maintenance	2.775254e-3
GO:2000271	positive regulation of fibroblast apoptosis	2.779348e-3
GO:2000270	negative regulation of fibroblast apoptosis	2.779348e-3
GO:0006097	glyoxylate cycle	2.779348e-3
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	2.779348e-3
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	2.779348e-3
GO:0050691	regulation of defense response to virus by host	2.783401e-3
GO:0032388	positive regulation of intracellular transport	2.847777e-3
GO:0051238	sequestering of metal ion	2.850883e-3
GO:0060052	neurofilament cytoskeleton organization	2.916404e-3
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.969519e-3
GO:0009103	lipopolysaccharide biosynthetic process	2.981384e-3
GO:0032647	regulation of interferon-alpha production	2.981384e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	3.001306e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	3.066957e-3
GO:0009146	purine nucleoside triphosphate catabolic process	3.131779e-3
GO:0043687	post-translational protein modification	3.232952e-3
GO:0060084	synaptic transmission involved in micturition	3.273123e-3
GO:0042307	positive regulation of protein import into nucleus	3.409650e-3
GO:0006268	DNA unwinding involved in replication	3.450032e-3
GO:0016180	snRNA processing	3.453962e-3
GO:0009143	nucleoside triphosphate catabolic process	3.555916e-3
GO:0070244	negative regulation of thymocyte apoptosis	3.682315e-3
GO:0061136	regulation of proteasomal protein catabolic process	3.706105e-3
GO:0008334	histone mRNA metabolic process	3.716682e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	3.724204e-3
GO:0021678	third ventricle development	3.735453e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	3.737589e-3
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	3.737589e-3
GO:0048255	mRNA stabilization	3.897299e-3
GO:0007530	sex determination	3.897299e-3
GO:0048382	mesendoderm development	3.932235e-3
GO:0032700	negative regulation of interleukin-17 production	4.023408e-3
GO:0006429	leucyl-tRNA aminoacylation	4.082091e-3
GO:0071380	cellular response to prostaglandin E stimulus	4.186934e-3
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	4.186934e-3
GO:0016139	glycoside catabolic process	4.186934e-3
GO:0002442	serotonin secretion involved in inflammatory response	4.186934e-3
GO:0002719	negative regulation of cytokine production involved in immune response	4.256714e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.277769e-3
GO:0006270	DNA-dependent DNA replication initiation	4.292567e-3
GO:0043248	proteasome assembly	4.292567e-3
GO:0009109	coenzyme catabolic process	4.349426e-3
GO:0045359	positive regulation of interferon-beta biosynthetic process	4.392936e-3
GO:0010447	response to acidity	4.563807e-3
GO:0021549	cerebellum development	4.692716e-3
GO:0021784	postganglionic parasympathetic nervous system development	4.759329e-3
GO:0060029	convergent extension involved in organogenesis	4.860590e-3
GO:0030902	hindbrain development	4.862511e-3
GO:0017144	drug metabolic process	4.938199e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	5.113561e-3
GO:0042273	ribosomal large subunit biogenesis	5.113561e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	5.193104e-3
GO:0035195	gene silencing by miRNA	5.207982e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	5.207982e-3
GO:0009144	purine nucleoside triphosphate metabolic process	5.234266e-3
GO:0051532	regulation of NFAT protein import into nucleus	5.283472e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	5.329005e-3
GO:0022904	respiratory electron transport chain	5.358799e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.467585e-3
GO:0061054	dermatome development	5.467585e-3
GO:0034441	plasma lipoprotein particle oxidation	5.467585e-3
GO:0051188	cofactor biosynthetic process	5.497573e-3
GO:0009314	response to radiation	5.497939e-3
GO:0045454	cell redox homeostasis	5.509931e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	5.577775e-3
GO:0031167	rRNA methylation	5.684503e-3
GO:0009088	threonine biosynthetic process	5.832163e-3
GO:0051610	serotonin uptake	5.832163e-3
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	5.832163e-3
GO:0009225	nucleotide-sugar metabolic process	5.832896e-3
GO:0002507	tolerance induction	5.930799e-3
GO:0022037	metencephalon development	5.944539e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	6.080560e-3
GO:0044265	cellular macromolecule catabolic process	6.126242e-3
GO:0042744	hydrogen peroxide catabolic process	6.195232e-3
GO:0048352	paraxial mesoderm structural organization	6.346513e-3
GO:0021998	neural plate mediolateral regionalization	6.346513e-3
GO:0048743	positive regulation of skeletal muscle fiber development	6.375637e-3
GO:0007096	regulation of exit from mitosis	6.380127e-3
GO:0060009	Sertoli cell development	6.475237e-3
GO:0035194	posttranscriptional gene silencing by RNA	6.475710e-3
GO:0071481	cellular response to X-ray	6.664260e-3
GO:0009199	ribonucleoside triphosphate metabolic process	6.694681e-3
GO:0006457	protein folding	6.758483e-3
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	6.773742e-3
GO:0050935	iridophore differentiation	6.790604e-3
GO:0048937	lateral line nerve glial cell development	6.790604e-3
GO:0030168	platelet activation	6.841746e-3
GO:0048496	maintenance of organ identity	7.000394e-3
GO:0014816	satellite cell differentiation	7.000394e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.000394e-3
GO:0048818	positive regulation of hair follicle maturation	7.012771e-3
GO:2000194	regulation of female gonad development	7.012771e-3
GO:0000281	cytokinesis after mitosis	7.012771e-3
GO:0001510	RNA methylation	7.063791e-3
GO:0034764	positive regulation of transmembrane transport	7.102478e-3
GO:0044240	multicellular organismal lipid catabolic process	7.112373e-3
GO:0002090	regulation of receptor internalization	7.254516e-3
GO:0006974	response to DNA damage stimulus	7.350425e-3
GO:0071472	cellular response to salt stress	7.420277e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	7.420277e-3
GO:0000729	DNA double-strand break processing	7.420277e-3
GO:0071300	cellular response to retinoic acid	7.432997e-3
GO:0051926	negative regulation of calcium ion transport	7.486368e-3
GO:0090316	positive regulation of intracellular protein transport	7.522420e-3
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	7.569055e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	7.727093e-3
GO:0045104	intermediate filament cytoskeleton organization	7.767993e-3
GO:0032728	positive regulation of interferon-beta production	7.782766e-3
GO:0070922	small RNA loading onto RISC	7.803369e-3
GO:0006666	3-keto-sphinganine metabolic process	7.803369e-3
GO:0046626	regulation of insulin receptor signaling pathway	7.813826e-3
GO:0043409	negative regulation of MAPKKK cascade	7.848820e-3
GO:0042401	cellular biogenic amine biosynthetic process	7.923407e-3
GO:0034629	cellular protein complex localization	7.970498e-3
GO:0018410	C-terminal protein amino acid modification	7.970498e-3
GO:0060152	microtubule-based peroxisome localization	8.218365e-3
GO:0045333	cellular respiration	8.234503e-3
GO:0009452	RNA capping	8.316932e-3
GO:2000655	negative regulation of cellular response to testosterone stimulus	8.450753e-3
GO:0051097	negative regulation of helicase activity	8.450753e-3
GO:0006343	establishment of chromatin silencing	8.450753e-3
GO:0031937	positive regulation of chromatin silencing	8.450753e-3
GO:0006422	aspartyl-tRNA aminoacylation	8.526922e-3
GO:0009108	coenzyme biosynthetic process	8.547793e-3
GO:0042424	catecholamine catabolic process	8.573308e-3
GO:0019673	GDP-mannose metabolic process	8.602808e-3
GO:0043046	DNA methylation involved in gamete generation	8.680564e-3
GO:0021548	pons development	8.803466e-3
GO:0051865	protein autoubiquitination	8.867214e-3
GO:0016090	prenol metabolic process	8.928104e-3
GO:0033084	regulation of immature T cell proliferation in thymus	9.059321e-3
GO:0008088	axon cargo transport	9.140258e-3
GO:0009154	purine ribonucleotide catabolic process	9.278641e-3
GO:0007549	dosage compensation	9.299349e-3
GO:0044271	cellular nitrogen compound biosynthetic process	9.355007e-3
GO:0046940	nucleoside monophosphate phosphorylation	9.400970e-3
GO:0034421	post-translational protein acetylation	9.400970e-3
GO:0030421	defecation	9.400970e-3
GO:0007099	centriole replication	9.471363e-3
GO:0000959	mitochondrial RNA metabolic process	9.471363e-3
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	9.530570e-3
GO:0033566	gamma-tubulin complex localization	9.530570e-3
GO:0001834	trophectodermal cell proliferation	9.530570e-3
GO:0032481	positive regulation of type I interferon production	9.550867e-3
GO:0009141	nucleoside triphosphate metabolic process	9.557326e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	9.588936e-3
GO:0071299	cellular response to vitamin A	9.730058e-3
GO:0030210	heparin biosynthetic process	9.854364e-3
GO:0030432	peristalsis	9.930002e-3
GO:0061056	sclerotome development	9.971355e-3
GO:0070059	apoptosis in response to endoplasmic reticulum stress	1.006701e-2
GO:0002701	negative regulation of production of molecular mediator of immune response	1.015477e-2
GO:0034645	cellular macromolecule biosynthetic process	1.023344e-2
GO:0002763	positive regulation of myeloid leukocyte differentiation	1.025743e-2
GO:0046112	nucleobase biosynthetic process	1.032725e-2
GO:0009261	ribonucleotide catabolic process	1.037160e-2
GO:0006047	UDP-N-acetylglucosamine metabolic process	1.039172e-2
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.040698e-2
GO:0048630	skeletal muscle tissue growth	1.046926e-2
GO:0032933	SREBP-mediated signaling pathway	1.056517e-2
GO:0006184	GTP catabolic process	1.059463e-2
GO:0046477	glycosylceramide catabolic process	1.068047e-2
GO:2000195	negative regulation of female gonad development	1.068047e-2
GO:0018130	heterocycle biosynthetic process	1.115318e-2
GO:0060055	angiogenesis involved in wound healing	1.116993e-2
GO:0018195	peptidyl-arginine modification	1.116993e-2
GO:0051764	actin crosslink formation	1.118553e-2
GO:0043488	regulation of mRNA stability	1.139082e-2
GO:2000018	regulation of male gonad development	1.156241e-2
GO:0072539	T-helper 17 cell differentiation	1.163657e-2
GO:0021536	diencephalon development	1.181117e-2
GO:0048260	positive regulation of receptor-mediated endocytosis	1.211193e-2
GO:0006612	protein targeting to membrane	1.211896e-2
GO:0007049	cell cycle	1.223919e-2
GO:0048880	sensory system development	1.249420e-2
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.249420e-2
GO:0035608	protein deglutamylation	1.249420e-2
GO:0002224	toll-like receptor signaling pathway	1.253100e-2
GO:0035065	regulation of histone acetylation	1.256788e-2
GO:0030719	P granule organization	1.283420e-2