Novel motif:43

name:	motif43_CCCWGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006955	immune response	1.652121e-30
GO:0006952	defense response	4.095253e-28
GO:0006954	inflammatory response	3.896688e-20
GO:0071732	cellular response to nitric oxide	4.021675e-19
GO:0002376	immune system process	5.637123e-18
GO:0045087	innate immune response	5.364561e-16
GO:0071731	response to nitric oxide	1.095755e-13
GO:0007509	mesoderm migration involved in gastrulation	1.725644e-13
GO:0034340	response to type I interferon	2.088184e-13
GO:0060337	type I interferon-mediated signaling pathway	2.147029e-13
GO:0008078	mesodermal cell migration	1.278854e-12
GO:0002682	regulation of immune system process	1.491119e-12
GO:0009612	response to mechanical stimulus	1.653626e-12
GO:0009605	response to external stimulus	6.552023e-12
GO:0010033	response to organic substance	8.628763e-12
GO:0070849	response to epidermal growth factor stimulus	9.490442e-12
GO:0007586	digestion	1.081475e-11
GO:0035814	negative regulation of renal sodium excretion	1.485814e-11
GO:0010985	negative regulation of lipoprotein particle clearance	4.271018e-11
GO:0001817	regulation of cytokine production	4.983770e-11
GO:0050896	response to stimulus	7.045515e-11
GO:0042424	catecholamine catabolic process	9.454898e-11
GO:0010941	regulation of cell death	1.071641e-10
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.417967e-10
GO:0019221	cytokine-mediated signaling pathway	2.433345e-10
GO:0002443	leukocyte mediated immunity	2.524107e-10
GO:0030185	nitric oxide transport	2.783750e-10
GO:0022617	extracellular matrix disassembly	3.750144e-10
GO:0010243	response to organic nitrogen	4.868484e-10
GO:0030010	establishment of cell polarity	5.250875e-10
GO:0001101	response to acid	7.114715e-10
GO:0031960	response to corticosteroid stimulus	1.056492e-9
GO:0051707	response to other organism	1.296504e-9
GO:0060290	transdifferentiation	1.328773e-9
GO:0002684	positive regulation of immune system process	1.392838e-9
GO:0032203	telomere formation via telomerase	1.549575e-9
GO:0009607	response to biotic stimulus	2.130538e-9
GO:0043200	response to amino acid stimulus	2.155669e-9
GO:0033986	response to methanol	2.211935e-9
GO:0046687	response to chromate	2.211935e-9
GO:0048545	response to steroid hormone stimulus	2.354199e-9
GO:0000302	response to reactive oxygen species	2.618237e-9
GO:0045026	plasma membrane fusion	2.674615e-9
GO:0048584	positive regulation of response to stimulus	2.752980e-9
GO:0042981	regulation of apoptosis	3.502706e-9
GO:0043067	regulation of programmed cell death	3.538055e-9
GO:0071417	cellular response to organic nitrogen	4.115900e-9
GO:0034014	response to triglyceride	4.543619e-9
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	5.945344e-9
GO:0007585	respiratory gaseous exchange	9.212380e-9
GO:0065008	regulation of biological quality	9.548626e-9
GO:0009253	peptidoglycan catabolic process	1.024466e-8
GO:0009611	response to wounding	1.137546e-8
GO:0044281	small molecule metabolic process	1.180278e-8
GO:0008610	lipid biosynthetic process	1.243957e-8
GO:0071418	cellular response to amine stimulus	1.319913e-8
GO:0007154	cell communication	1.378893e-8
GO:0009628	response to abiotic stimulus	1.532083e-8
GO:0019882	antigen processing and presentation	1.546051e-8
GO:0001819	positive regulation of cytokine production	1.583968e-8
GO:0023052	signaling	1.756279e-8
GO:0045834	positive regulation of lipid metabolic process	1.940467e-8
GO:0042420	dopamine catabolic process	2.217878e-8
GO:0071260	cellular response to mechanical stimulus	2.342687e-8
GO:0009719	response to endogenous stimulus	2.429291e-8
GO:0010872	regulation of cholesterol esterification	2.473828e-8
GO:0016064	immunoglobulin mediated immune response	2.526981e-8
GO:0070417	cellular response to cold	2.709066e-8
GO:0002449	lymphocyte mediated immunity	3.313638e-8
GO:0042592	homeostatic process	3.973593e-8
GO:0071230	cellular response to amino acid stimulus	4.105974e-8
GO:0034097	response to cytokine stimulus	4.304087e-8
GO:0046902	regulation of mitochondrial membrane permeability	4.590053e-8
GO:0050776	regulation of immune response	4.753600e-8
GO:0044255	cellular lipid metabolic process	5.261144e-8
GO:0006342	chromatin silencing	5.527642e-8
GO:0007568	aging	5.566104e-8
GO:0006629	lipid metabolic process	5.802416e-8
GO:0016052	carbohydrate catabolic process	6.015702e-8
GO:0002237	response to molecule of bacterial origin	6.558806e-8
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.851869e-8
GO:0014075	response to amine stimulus	7.281177e-8
GO:0044283	small molecule biosynthetic process	7.441396e-8
GO:0009966	regulation of signal transduction	7.941366e-8
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	7.962685e-8
GO:0032916	positive regulation of transforming growth factor beta3 production	8.821362e-8
GO:0019724	B cell mediated immunity	8.916804e-8
GO:0042221	response to chemical stimulus	9.706334e-8
GO:0048583	regulation of response to stimulus	9.919739e-8
GO:0006022	aminoglycan metabolic process	1.009513e-7
GO:0002149	hypochlorous acid biosynthetic process	1.085852e-7
GO:0010536	positive regulation of activation of Janus kinase activity	1.088525e-7
GO:0042542	response to hydrogen peroxide	1.233364e-7
GO:0032496	response to lipopolysaccharide	1.233427e-7
GO:0071229	cellular response to acid	1.265087e-7
GO:0006909	phagocytosis	1.345459e-7
GO:0045471	response to ethanol	1.359773e-7
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.378605e-7
GO:0007342	fusion of sperm to egg plasma membrane	1.384678e-7
GO:0045940	positive regulation of steroid metabolic process	1.517341e-7
GO:0048519	negative regulation of biological process	1.557539e-7
GO:0090130	tissue migration	1.560016e-7
GO:0021984	adenohypophysis development	1.815782e-7
GO:0010873	positive regulation of cholesterol esterification	1.850478e-7
GO:0044062	regulation of excretion	1.856744e-7
GO:0007165	signal transduction	1.886331e-7
GO:0002252	immune effector process	1.922591e-7
GO:0051384	response to glucocorticoid stimulus	2.181515e-7
GO:0051704	multi-organism process	2.253935e-7
GO:0023051	regulation of signaling	2.318176e-7
GO:0035813	regulation of renal sodium excretion	2.345266e-7
GO:0007166	cell surface receptor linked signaling pathway	2.397883e-7
GO:0045814	negative regulation of gene expression, epigenetic	2.647845e-7
GO:0009895	negative regulation of catabolic process	2.750406e-7
GO:0033189	response to vitamin A	2.974651e-7
GO:0006631	fatty acid metabolic process	3.285192e-7
GO:0060333	interferon-gamma-mediated signaling pathway	3.361947e-7
GO:0009967	positive regulation of signal transduction	3.426060e-7
GO:0006953	acute-phase response	3.701151e-7
GO:0044236	multicellular organismal metabolic process	4.423180e-7
GO:0090218	positive regulation of lipid kinase activity	4.557392e-7
GO:0010741	negative regulation of intracellular protein kinase cascade	4.851528e-7
GO:0015671	oxygen transport	5.275926e-7
GO:0002253	activation of immune response	5.297234e-7
GO:0031667	response to nutrient levels	5.462092e-7
GO:0045730	respiratory burst	5.579041e-7
GO:0032910	regulation of transforming growth factor beta3 production	5.840366e-7
GO:0010900	negative regulation of phosphatidylcholine catabolic process	6.267023e-7
GO:0032012	regulation of ARF protein signal transduction	6.303864e-7
GO:0008284	positive regulation of cell proliferation	6.388992e-7
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	6.442028e-7
GO:0009991	response to extracellular stimulus	6.445842e-7
GO:0002526	acute inflammatory response	6.668088e-7
GO:0051937	catecholamine transport	6.710474e-7
GO:0002250	adaptive immune response	6.922626e-7
GO:0046164	alcohol catabolic process	7.237629e-7
GO:0002579	positive regulation of antigen processing and presentation	7.664862e-7
GO:0048878	chemical homeostasis	7.922084e-7
GO:0032202	telomere assembly	8.153405e-7
GO:0019321	pentose metabolic process	8.729189e-7
GO:0043086	negative regulation of catalytic activity	8.924141e-7
GO:0000413	protein peptidyl-prolyl isomerization	1.011173e-6
GO:0060548	negative regulation of cell death	1.076514e-6
GO:0060326	cell chemotaxis	1.077413e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.125697e-6
GO:0015844	monoamine transport	1.257819e-6
GO:0050830	defense response to Gram-positive bacterium	1.324297e-6
GO:0043066	negative regulation of apoptosis	1.454586e-6
GO:0051591	response to cAMP	1.455213e-6
GO:0050778	positive regulation of immune response	1.520338e-6
GO:0033273	response to vitamin	1.631864e-6
GO:0018208	peptidyl-proline modification	1.666935e-6
GO:0001880	Mullerian duct regression	1.728783e-6
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.750948e-6
GO:0046949	fatty-acyl-CoA biosynthetic process	1.773796e-6
GO:0048518	positive regulation of biological process	1.806493e-6
GO:0051291	protein heterooligomerization	1.811911e-6
GO:0032787	monocarboxylic acid metabolic process	2.097913e-6
GO:0046394	carboxylic acid biosynthetic process	2.254793e-6
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.326754e-6
GO:0010897	negative regulation of triglyceride catabolic process	2.326754e-6
GO:0002251	organ or tissue specific immune response	2.396644e-6
GO:0060696	regulation of phospholipid catabolic process	2.437890e-6
GO:0046314	phosphocreatine biosynthetic process	2.459085e-6
GO:0015669	gas transport	2.500515e-6
GO:0021858	GABAergic neuron differentiation in basal ganglia	2.682427e-6
GO:0051005	negative regulation of lipoprotein lipase activity	2.682427e-6
GO:0032094	response to food	2.787378e-6
GO:0007163	establishment or maintenance of cell polarity	2.873643e-6
GO:0042992	negative regulation of transcription factor import into nucleus	2.935325e-6
GO:0071345	cellular response to cytokine stimulus	2.968650e-6
GO:0007006	mitochondrial membrane organization	3.070076e-6
GO:0042396	phosphagen biosynthetic process	3.190794e-6
GO:0042994	cytoplasmic sequestering of transcription factor	3.457573e-6
GO:0048247	lymphocyte chemotaxis	3.507533e-6
GO:0034505	tooth mineralization	3.571496e-6
GO:0045338	farnesyl diphosphate metabolic process	3.635070e-6
GO:0010875	positive regulation of cholesterol efflux	3.670155e-6
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	3.719076e-6
GO:0032663	regulation of interleukin-2 production	3.800281e-6
GO:0016458	gene silencing	3.909074e-6
GO:0010646	regulation of cell communication	3.979804e-6
GO:0051001	negative regulation of nitric-oxide synthase activity	4.017826e-6
GO:0000920	cytokinetic cell separation	4.023909e-6
GO:0051179	localization	4.221191e-6
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	4.377345e-6
GO:0006950	response to stress	4.401587e-6
GO:0043069	negative regulation of programmed cell death	4.402288e-6
GO:0048352	paraxial mesoderm structural organization	4.779123e-6
GO:0021998	neural plate mediolateral regionalization	4.779123e-6
GO:0042347	negative regulation of NF-kappaB import into nucleus	4.789581e-6
GO:0072132	mesenchyme morphogenesis	4.832931e-6
GO:0031330	negative regulation of cellular catabolic process	4.915752e-6
GO:0006026	aminoglycan catabolic process	5.111862e-6
GO:0008217	regulation of blood pressure	5.326454e-6
GO:0007296	vitellogenesis	5.370399e-6
GO:0019048	virus-host interaction	5.469477e-6
GO:0019049	evasion of host defenses by virus	5.647848e-6
GO:0010988	regulation of low-density lipoprotein particle clearance	5.702601e-6
GO:0007183	SMAD protein complex assembly	5.715289e-6
GO:0044258	intestinal lipid catabolic process	5.757193e-6
GO:0018350	protein esterification	5.757193e-6
GO:0009725	response to hormone stimulus	5.802229e-6
GO:0051220	cytoplasmic sequestering of protein	5.918852e-6
GO:0044341	sodium-dependent phosphate transport	6.043521e-6
GO:0032088	negative regulation of NF-kappaB transcription factor activity	6.178290e-6
GO:0048535	lymph node development	6.329797e-6
GO:0045806	negative regulation of endocytosis	6.735740e-6
GO:0044092	negative regulation of molecular function	6.754142e-6
GO:0034201	response to oleic acid	6.953020e-6
GO:0048255	mRNA stabilization	7.586309e-6
GO:0043550	regulation of lipid kinase activity	7.656723e-6
GO:0043300	regulation of leukocyte degranulation	7.826255e-6
GO:0009617	response to bacterium	8.003408e-6
GO:0070887	cellular response to chemical stimulus	8.171981e-6
GO:0042177	negative regulation of protein catabolic process	8.255342e-6
GO:0007179	transforming growth factor beta receptor signaling pathway	8.639942e-6
GO:0048002	antigen processing and presentation of peptide antigen	8.671565e-6
GO:0006007	glucose catabolic process	8.919209e-6
GO:0030203	glycosaminoglycan metabolic process	9.562559e-6
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.095948e-5
GO:0034341	response to interferon-gamma	1.128572e-5
GO:0050764	regulation of phagocytosis	1.137319e-5
GO:0060644	mammary gland epithelial cell differentiation	1.138260e-5
GO:0016044	cellular membrane organization	1.157618e-5
GO:0050865	regulation of cell activation	1.181366e-5
GO:0014070	response to organic cyclic compound	1.190742e-5
GO:0061180	mammary gland epithelium development	1.253580e-5
GO:0051051	negative regulation of transport	1.262983e-5
GO:0051239	regulation of multicellular organismal process	1.277584e-5
GO:0006916	anti-apoptosis	1.363224e-5
GO:0050832	defense response to fungus	1.369263e-5
GO:0061024	membrane organization	1.371450e-5
GO:0044130	negative regulation of growth of symbiont in host	1.440628e-5
GO:0046514	ceramide catabolic process	1.470577e-5
GO:0007109	cytokinesis, completion of separation	1.484489e-5
GO:0002694	regulation of leukocyte activation	1.489274e-5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.527109e-5
GO:0002679	respiratory burst involved in defense response	1.547188e-5
GO:0044259	multicellular organismal macromolecule metabolic process	1.685259e-5
GO:0051251	positive regulation of lymphocyte activation	1.725134e-5
GO:0071705	nitrogen compound transport	1.777953e-5
GO:0002098	tRNA wobble uridine modification	1.807152e-5
GO:0034227	tRNA thio-modification	1.807152e-5
GO:0051246	regulation of protein metabolic process	1.852091e-5
GO:0006014	D-ribose metabolic process	1.885730e-5
GO:0006810	transport	2.003996e-5
GO:0044275	cellular carbohydrate catabolic process	2.077662e-5
GO:0010984	regulation of lipoprotein particle clearance	2.142860e-5
GO:0007259	JAK-STAT cascade	2.214696e-5
GO:0010627	regulation of intracellular protein kinase cascade	2.221355e-5
GO:0048261	negative regulation of receptor-mediated endocytosis	2.272082e-5
GO:0002886	regulation of myeloid leukocyte mediated immunity	2.286713e-5
GO:0019432	triglyceride biosynthetic process	2.345215e-5
GO:0043304	regulation of mast cell degranulation	2.433927e-5
GO:0071299	cellular response to vitamin A	2.486495e-5
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	2.526252e-5
GO:0051249	regulation of lymphocyte activation	2.530670e-5
GO:0002764	immune response-regulating signaling pathway	2.545553e-5
GO:0006633	fatty acid biosynthetic process	2.785801e-5
GO:0007000	nucleolus organization	2.786374e-5
GO:0051234	establishment of localization	2.792335e-5
GO:0051716	cellular response to stimulus	2.863955e-5
GO:0008366	axon ensheathment	2.869295e-5
GO:0050801	ion homeostasis	2.912887e-5
GO:0042552	myelination	3.087930e-5
GO:0050848	regulation of calcium-mediated signaling	3.088364e-5
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	3.147790e-5
GO:0016126	sterol biosynthetic process	3.174429e-5
GO:0003218	cardiac left ventricle formation	3.185392e-5
GO:0042127	regulation of cell proliferation	3.239183e-5
GO:0030595	leukocyte chemotaxis	3.243420e-5
GO:0007181	transforming growth factor beta receptor complex assembly	3.253105e-5
GO:0006082	organic acid metabolic process	3.266166e-5
GO:0033211	adiponectin-mediated signaling pathway	3.274089e-5
GO:0003334	keratinocyte development	3.546165e-5
GO:0032963	collagen metabolic process	3.574963e-5
GO:0070542	response to fatty acid	3.579374e-5
GO:0019320	hexose catabolic process	3.589485e-5
GO:0050829	defense response to Gram-negative bacterium	3.608058e-5
GO:0006690	icosanoid metabolic process	3.621636e-5
GO:0032964	collagen biosynthetic process	3.649405e-5
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	3.709597e-5
GO:0055080	cation homeostasis	3.832381e-5
GO:0022009	central nervous system vasculogenesis	3.846092e-5
GO:0071346	cellular response to interferon-gamma	3.911767e-5
GO:0033239	negative regulation of cellular amine metabolic process	4.101710e-5
GO:0002478	antigen processing and presentation of exogenous peptide antigen	4.111558e-5
GO:0002218	activation of innate immune response	4.176824e-5
GO:0006544	glycine metabolic process	4.233203e-5
GO:0032879	regulation of localization	4.391366e-5
GO:0071300	cellular response to retinoic acid	4.430595e-5
GO:0015937	coenzyme A biosynthetic process	4.474868e-5
GO:0030913	paranodal junction assembly	4.540937e-5
GO:0060346	bone trabecula formation	4.557413e-5
GO:0043249	erythrocyte maturation	4.609843e-5
GO:0033559	unsaturated fatty acid metabolic process	4.674271e-5
GO:0060764	cell-cell signaling involved in mammary gland development	4.729695e-5
GO:0042503	tyrosine phosphorylation of Stat3 protein	5.006637e-5
GO:0042398	cellular modified amino acid biosynthetic process	5.069568e-5
GO:0009308	amine metabolic process	5.086486e-5
GO:0001973	adenosine receptor signaling pathway	5.122472e-5
GO:0033993	response to lipid	5.298226e-5
GO:0031347	regulation of defense response	5.333270e-5
GO:0007253	cytoplasmic sequestering of NF-kappaB	5.360647e-5
GO:0010888	negative regulation of lipid storage	5.368927e-5
GO:0010647	positive regulation of cell communication	5.448616e-5
GO:0046320	regulation of fatty acid oxidation	5.548234e-5
GO:0006637	acyl-CoA metabolic process	5.568198e-5
GO:0002828	regulation of type 2 immune response	5.609456e-5
GO:0009583	detection of light stimulus	5.634541e-5
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5.693077e-5
GO:0071391	cellular response to estrogen stimulus	5.904605e-5
GO:0071214	cellular response to abiotic stimulus	5.988964e-5
GO:0046365	monosaccharide catabolic process	6.114916e-5
GO:0042133	neurotransmitter metabolic process	6.119011e-5
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	6.387728e-5
GO:0046502	uroporphyrinogen III metabolic process	6.452219e-5
GO:0046128	purine ribonucleoside metabolic process	6.468256e-5
GO:0019216	regulation of lipid metabolic process	6.656035e-5
GO:0046007	negative regulation of activated T cell proliferation	6.701762e-5
GO:0002523	leukocyte migration involved in inflammatory response	6.701762e-5
GO:0046822	regulation of nucleocytoplasmic transport	6.844480e-5
GO:0008063	Toll signaling pathway	6.855966e-5
GO:0035556	intracellular signal transduction	6.886191e-5
GO:0006692	prostanoid metabolic process	6.935521e-5
GO:0032526	response to retinoic acid	6.990359e-5
GO:0050900	leukocyte migration	7.033032e-5
GO:0019884	antigen processing and presentation of exogenous antigen	7.056392e-5
GO:0002921	negative regulation of humoral immune response	7.158484e-5
GO:0009414	response to water deprivation	7.194135e-5
GO:0015872	dopamine transport	7.293736e-5
GO:0032456	endocytic recycling	7.310016e-5
GO:0032506	cytokinetic process	7.356134e-5
GO:0015840	urea transport	7.356134e-5
GO:0007584	response to nutrient	7.359255e-5
GO:0002432	granuloma formation	7.435962e-5
GO:0061383	trabecula morphogenesis	7.437759e-5
GO:0022415	viral reproductive process	7.448263e-5
GO:0032376	positive regulation of cholesterol transport	7.464553e-5
GO:0030334	regulation of cell migration	7.529867e-5
GO:0009416	response to light stimulus	7.629519e-5
GO:0023056	positive regulation of signaling	7.677213e-5
GO:0042942	D-serine transport	7.999909e-5
GO:0030953	astral microtubule organization	8.025650e-5
GO:0030198	extracellular matrix organization	8.383076e-5
GO:0044241	lipid digestion	8.447860e-5
GO:0042278	purine nucleoside metabolic process	8.639382e-5
GO:0010740	positive regulation of intracellular protein kinase cascade	8.667486e-5
GO:0048710	regulation of astrocyte differentiation	8.701949e-5
GO:0060708	spongiotrophoblast differentiation	8.849894e-5
GO:0042108	positive regulation of cytokine biosynthetic process	9.201612e-5
GO:0006032	chitin catabolic process	9.209446e-5
GO:0001300	chronological cell aging	9.244550e-5
GO:0007263	nitric oxide mediated signal transduction	9.314380e-5
GO:0003084	positive regulation of systemic arterial blood pressure	9.379841e-5
GO:0000132	establishment of mitotic spindle orientation	9.411050e-5
GO:0060749	mammary gland alveolus development	9.421941e-5
GO:0018193	peptidyl-amino acid modification	9.491506e-5
GO:0065007	biological regulation	9.653199e-5
GO:0055085	transmembrane transport	9.669214e-5
GO:0050863	regulation of T cell activation	9.675177e-5
GO:0050867	positive regulation of cell activation	9.913526e-5
GO:0010824	regulation of centrosome duplication	1.010269e-4
GO:0060973	cell migration involved in heart development	1.036462e-4
GO:0009306	protein secretion	1.046425e-4
GO:0045088	regulation of innate immune response	1.048431e-4
GO:0006695	cholesterol biosynthetic process	1.061933e-4
GO:0016139	glycoside catabolic process	1.080042e-4
GO:0045651	positive regulation of macrophage differentiation	1.127633e-4
GO:0016137	glycoside metabolic process	1.177171e-4
GO:0002696	positive regulation of leukocyte activation	1.189015e-4
GO:0006662	glycerol ether metabolic process	1.197755e-4
GO:0070208	protein heterotrimerization	1.215083e-4
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.215324e-4
GO:0001957	intramembranous ossification	1.239946e-4
GO:0071383	cellular response to steroid hormone stimulus	1.241952e-4
GO:0048241	epinephrine transport	1.254929e-4
GO:0006400	tRNA modification	1.261093e-4
GO:0014829	vascular smooth muscle contraction	1.261254e-4
GO:0072593	reactive oxygen species metabolic process	1.263061e-4
GO:0006720	isoprenoid metabolic process	1.266542e-4
GO:0015879	carnitine transport	1.276744e-4
GO:2000145	regulation of cell motility	1.276855e-4
GO:0042440	pigment metabolic process	1.287658e-4
GO:0032312	regulation of ARF GTPase activity	1.291971e-4
GO:0032703	negative regulation of interleukin-2 production	1.301156e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.321258e-4
GO:0031133	regulation of axon diameter	1.332503e-4
GO:0060480	lung goblet cell differentiation	1.344951e-4
GO:0044240	multicellular organismal lipid catabolic process	1.361133e-4
GO:0032880	regulation of protein localization	1.365655e-4
GO:0002513	tolerance induction to self antigen	1.417941e-4
GO:0046434	organophosphate catabolic process	1.455441e-4
GO:0000090	mitotic anaphase	1.455441e-4
GO:0060482	lobar bronchus development	1.461502e-4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	1.477548e-4
GO:0046483	heterocycle metabolic process	1.493719e-4
GO:0046730	induction of host immune response by virus	1.499326e-4
GO:0046456	icosanoid biosynthetic process	1.514173e-4
GO:0034763	negative regulation of transmembrane transport	1.526616e-4
GO:0046498	S-adenosylhomocysteine metabolic process	1.541011e-4
GO:0043407	negative regulation of MAP kinase activity	1.556631e-4
GO:0042744	hydrogen peroxide catabolic process	1.565299e-4
GO:0042454	ribonucleoside catabolic process	1.627090e-4
GO:0032288	myelin assembly	1.650870e-4
GO:0032740	positive regulation of interleukin-17 production	1.654934e-4
GO:0048523	negative regulation of cellular process	1.675146e-4
GO:0009749	response to glucose stimulus	1.679237e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.688430e-4
GO:0046504	glycerol ether biosynthetic process	1.704397e-4
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	1.718269e-4
GO:0035411	catenin import into nucleus	1.725079e-4
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	1.764646e-4
GO:0019752	carboxylic acid metabolic process	1.781015e-4
GO:0050747	positive regulation of lipoprotein metabolic process	1.792469e-4
GO:0042493	response to drug	1.853296e-4
GO:0008065	establishment of blood-nerve barrier	1.867633e-4
GO:0051241	negative regulation of multicellular organismal process	1.873017e-4
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1.888479e-4
GO:0060620	regulation of cholesterol import	1.920634e-4
GO:0009259	ribonucleotide metabolic process	1.943799e-4
GO:0000089	mitotic metaphase	1.944685e-4
GO:0009150	purine ribonucleotide metabolic process	1.976124e-4
GO:0006740	NADPH regeneration	1.986081e-4
GO:0006636	unsaturated fatty acid biosynthetic process	1.990593e-4
GO:0060659	nipple sheath formation	2.062749e-4
GO:0060649	mammary gland bud elongation	2.062749e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	2.086847e-4
GO:0006766	vitamin metabolic process	2.113609e-4
GO:0060712	spongiotrophoblast layer development	2.122754e-4
GO:0048477	oogenesis	2.129522e-4
GO:0034142	toll-like receptor 4 signaling pathway	2.134356e-4
GO:0043301	negative regulation of leukocyte degranulation	2.134407e-4
GO:0006959	humoral immune response	2.199690e-4
GO:0014910	regulation of smooth muscle cell migration	2.239282e-4
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	2.251383e-4
GO:0014874	response to stimulus involved in regulation of muscle adaptation	2.264192e-4
GO:0060262	negative regulation of N-terminal protein palmitoylation	2.272410e-4
GO:0060343	trabecula formation	2.286054e-4
GO:0009119	ribonucleoside metabolic process	2.290662e-4
GO:0070201	regulation of establishment of protein localization	2.304762e-4
GO:0060341	regulation of cellular localization	2.319392e-4
GO:0043206	fibril organization	2.324826e-4
GO:0060980	cell migration involved in coronary vasculogenesis	2.412641e-4
GO:0051973	positive regulation of telomerase activity	2.435765e-4
GO:0016090	prenol metabolic process	2.435765e-4
GO:2000147	positive regulation of cell motility	2.481681e-4
GO:0009309	amine biosynthetic process	2.490622e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	2.492108e-4
GO:0002920	regulation of humoral immune response	2.541322e-4
GO:0071310	cellular response to organic substance	2.543121e-4
GO:0050790	regulation of catalytic activity	2.566460e-4
GO:0046626	regulation of insulin receptor signaling pathway	2.574366e-4
GO:0040007	growth	2.601861e-4
GO:0045351	type I interferon biosynthetic process	2.615792e-4
GO:0072521	purine-containing compound metabolic process	2.643053e-4
GO:0071294	cellular response to zinc ion	2.649328e-4
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	2.658936e-4
GO:0034767	positive regulation of ion transmembrane transport	2.658936e-4
GO:0006098	pentose-phosphate shunt	2.689430e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	2.697173e-4
GO:0060621	negative regulation of cholesterol import	2.714283e-4
GO:0048771	tissue remodeling	2.720660e-4
GO:0046165	alcohol biosynthetic process	2.722755e-4
GO:0009620	response to fungus	2.728061e-4
GO:0042180	cellular ketone metabolic process	2.739746e-4
GO:0042136	neurotransmitter biosynthetic process	2.751787e-4
GO:0051347	positive regulation of transferase activity	2.775167e-4
GO:0009145	purine nucleoside triphosphate biosynthetic process	2.777146e-4
GO:0072376	protein activation cascade	2.829907e-4
GO:0045084	positive regulation of interleukin-12 biosynthetic process	2.855873e-4
GO:0051972	regulation of telomerase activity	2.863623e-4
GO:0009142	nucleoside triphosphate biosynthetic process	2.863919e-4
GO:0044243	multicellular organismal catabolic process	2.864224e-4
GO:0034134	toll-like receptor 2 signaling pathway	2.865879e-4
GO:0034130	toll-like receptor 1 signaling pathway	2.865879e-4
GO:0009201	ribonucleoside triphosphate biosynthetic process	2.923157e-4
GO:0048522	positive regulation of cellular process	2.975880e-4
GO:0046364	monosaccharide biosynthetic process	2.979944e-4
GO:0006754	ATP biosynthetic process	3.027021e-4
GO:0043901	negative regulation of multi-organism process	3.070836e-4
GO:0032845	negative regulation of homeostatic process	3.118456e-4
GO:0009301	snRNA transcription	3.149015e-4
GO:0006739	NADP metabolic process	3.161057e-4
GO:0060576	intestinal epithelial cell development	3.166321e-4
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	3.183747e-4
GO:0045777	positive regulation of blood pressure	3.196273e-4
GO:0032495	response to muramyl dipeptide	3.198215e-4
GO:0001661	conditioned taste aversion	3.202996e-4
GO:0006110	regulation of glycolysis	3.296436e-4
GO:0006812	cation transport	3.297637e-4
GO:0050663	cytokine secretion	3.313454e-4
GO:0032536	regulation of cell projection size	3.346072e-4
GO:0055072	iron ion homeostasis	3.360684e-4
GO:0048382	mesendoderm development	3.363537e-4
GO:0007602	phototransduction	3.448139e-4
GO:0035419	activation of MAPK activity involved in innate immune response	3.454013e-4
GO:0010951	negative regulation of endopeptidase activity	3.458777e-4
GO:0003417	growth plate cartilage development	3.474499e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0002739	regulation of cytokine secretion involved in immune response	1.625587e-10
GO:0002478	antigen processing and presentation of exogenous peptide antigen	4.393675e-10
GO:0060621	negative regulation of cholesterol import	6.036169e-10
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	8.271525e-10
GO:0009214	cyclic nucleotide catabolic process	1.142667e-9
GO:0010033	response to organic substance	1.971380e-9
GO:0060620	regulation of cholesterol import	2.332433e-9
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2.564271e-9
GO:0019884	antigen processing and presentation of exogenous antigen	3.556924e-9
GO:0060907	positive regulation of macrophage cytokine production	4.740162e-9
GO:0032103	positive regulation of response to external stimulus	7.324866e-9
GO:0009125	nucleoside monophosphate catabolic process	7.377837e-9
GO:0002687	positive regulation of leukocyte migration	8.606994e-9
GO:0002718	regulation of cytokine production involved in immune response	1.166280e-8
GO:0006518	peptide metabolic process	1.283861e-8
GO:0043647	inositol phosphate metabolic process	1.382541e-8
GO:0002443	leukocyte mediated immunity	1.403430e-8
GO:0006360	transcription from RNA polymerase I promoter	2.316744e-8
GO:0001961	positive regulation of cytokine-mediated signaling pathway	3.264733e-8
GO:0002688	regulation of leukocyte chemotaxis	4.125408e-8
GO:0034763	negative regulation of transmembrane transport	4.208794e-8
GO:0002690	positive regulation of leukocyte chemotaxis	4.674189e-8
GO:0034762	regulation of transmembrane transport	4.744437e-8
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.334767e-8
GO:0010897	negative regulation of triglyceride catabolic process	5.334767e-8
GO:0035691	macrophage migration inhibitory factor signaling pathway	6.295849e-8
GO:0051234	establishment of localization	7.303139e-8
GO:0002685	regulation of leukocyte migration	7.641393e-8
GO:0050713	negative regulation of interleukin-1 beta secretion	9.520810e-8
GO:0009895	negative regulation of catabolic process	9.861467e-8
GO:0046339	diacylglycerol metabolic process	1.212990e-7
GO:0002577	regulation of antigen processing and presentation	1.228545e-7
GO:0070536	protein K63-linked deubiquitination	1.248733e-7
GO:0051241	negative regulation of multicellular organismal process	1.330112e-7
GO:0002449	lymphocyte mediated immunity	1.332315e-7
GO:0002720	positive regulation of cytokine production involved in immune response	1.396460e-7
GO:0042221	response to chemical stimulus	1.698467e-7
GO:0002579	positive regulation of antigen processing and presentation	2.166327e-7
GO:0006198	cAMP catabolic process	2.251592e-7
GO:0010957	negative regulation of vitamin D biosynthetic process	2.260390e-7
GO:0048002	antigen processing and presentation of peptide antigen	2.346093e-7
GO:0090209	negative regulation of triglyceride metabolic process	3.456999e-7
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.497534e-7
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	5.054511e-7
GO:0019882	antigen processing and presentation	5.330951e-7
GO:0055085	transmembrane transport	5.543818e-7
GO:0046058	cAMP metabolic process	5.759758e-7
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.629338e-7
GO:0035094	response to nicotine	6.755747e-7
GO:0006116	NADH oxidation	7.055339e-7
GO:0001818	negative regulation of cytokine production	8.352542e-7
GO:0045933	positive regulation of muscle contraction	9.400359e-7
GO:0006810	transport	9.667158e-7
GO:0051085	chaperone mediated protein folding requiring cofactor	1.048727e-6
GO:0016064	immunoglobulin mediated immune response	1.181594e-6
GO:0045725	positive regulation of glycogen biosynthetic process	1.241214e-6
GO:0060760	positive regulation of response to cytokine stimulus	1.279564e-6
GO:0002252	immune effector process	1.321339e-6
GO:0006508	proteolysis	1.328823e-6
GO:0019724	B cell mediated immunity	1.640302e-6
GO:0050711	negative regulation of interleukin-1 secretion	1.827843e-6
GO:0050921	positive regulation of chemotaxis	1.839133e-6
GO:0050896	response to stimulus	2.094178e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	2.392140e-6
GO:0042069	regulation of catecholamine metabolic process	2.681905e-6
GO:0009187	cyclic nucleotide metabolic process	2.874760e-6
GO:0032652	regulation of interleukin-1 production	2.922243e-6
GO:0090075	relaxation of muscle	3.119351e-6
GO:0015074	DNA integration	3.245886e-6
GO:0051223	regulation of protein transport	3.609279e-6
GO:0032369	negative regulation of lipid transport	3.645929e-6
GO:0032651	regulation of interleukin-1 beta production	3.678714e-6
GO:0045833	negative regulation of lipid metabolic process	3.779786e-6
GO:0007588	excretion	3.803217e-6
GO:0051049	regulation of transport	3.985464e-6
GO:0009719	response to endogenous stimulus	4.076902e-6
GO:0002821	positive regulation of adaptive immune response	4.147374e-6
GO:0032675	regulation of interleukin-6 production	4.485313e-6
GO:0042311	vasodilation	4.513231e-6
GO:0008211	glucocorticoid metabolic process	4.534427e-6
GO:0001817	regulation of cytokine production	4.599743e-6
GO:0007021	tubulin complex assembly	4.661142e-6
GO:0006749	glutathione metabolic process	4.729250e-6
GO:0070228	regulation of lymphocyte apoptosis	4.751860e-6
GO:0070307	lens fiber cell development	5.211839e-6
GO:0042420	dopamine catabolic process	5.261210e-6
GO:0032879	regulation of localization	5.609616e-6
GO:0007586	digestion	6.126824e-6
GO:0002604	regulation of dendritic cell antigen processing and presentation	6.183552e-6
GO:0070141	response to UV-A	6.865091e-6
GO:0003084	positive regulation of systemic arterial blood pressure	6.957290e-6
GO:0061024	membrane organization	7.082554e-6
GO:0010982	regulation of high-density lipoprotein particle clearance	7.937872e-6
GO:0070509	calcium ion import	8.549193e-6
GO:0019218	regulation of steroid metabolic process	8.754952e-6
GO:0014075	response to amine stimulus	8.779156e-6
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	9.122763e-6
GO:0006629	lipid metabolic process	9.378287e-6
GO:0051179	localization	9.927832e-6
GO:0031330	negative regulation of cellular catabolic process	1.004721e-5
GO:0002830	positive regulation of type 2 immune response	1.037526e-5
GO:0016044	cellular membrane organization	1.038623e-5
GO:0043242	negative regulation of protein complex disassembly	1.162390e-5
GO:0002702	positive regulation of production of molecular mediator of immune response	1.258524e-5
GO:0050848	regulation of calcium-mediated signaling	1.264903e-5
GO:0042053	regulation of dopamine metabolic process	1.427515e-5
GO:0031347	regulation of defense response	1.436150e-5
GO:0002034	regulation of blood vessel size by renin-angiotensin	1.460739e-5
GO:0014070	response to organic cyclic compound	1.484414e-5
GO:0001885	endothelial cell development	1.497839e-5
GO:0042424	catecholamine catabolic process	1.572720e-5
GO:0030834	regulation of actin filament depolymerization	1.594262e-5
GO:0032957	inositol trisphosphate metabolic process	1.634938e-5
GO:0010935	regulation of macrophage cytokine production	1.645284e-5
GO:0070201	regulation of establishment of protein localization	1.657159e-5
GO:0070508	cholesterol import	1.962107e-5
GO:0044062	regulation of excretion	2.204419e-5
GO:0002238	response to molecule of fungal origin	2.221771e-5
GO:0032386	regulation of intracellular transport	2.236586e-5
GO:0050729	positive regulation of inflammatory response	2.464768e-5
GO:0030835	negative regulation of actin filament depolymerization	2.485865e-5
GO:0010038	response to metal ion	2.544751e-5
GO:0006544	glycine metabolic process	2.558632e-5
GO:0044255	cellular lipid metabolic process	2.631991e-5
GO:0045987	positive regulation of smooth muscle contraction	2.654194e-5
GO:0048520	positive regulation of behavior	2.772541e-5
GO:0031349	positive regulation of defense response	2.895093e-5
GO:0045932	negative regulation of muscle contraction	3.106820e-5
GO:0032715	negative regulation of interleukin-6 production	3.107490e-5
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.135446e-5
GO:0071310	cellular response to organic substance	3.154891e-5
GO:0032101	regulation of response to external stimulus	3.414567e-5
GO:0046890	regulation of lipid biosynthetic process	3.814983e-5
GO:0048146	positive regulation of fibroblast proliferation	3.831844e-5
GO:0007015	actin filament organization	3.905147e-5
GO:2000107	negative regulation of leukocyte apoptosis	4.107410e-5
GO:0006952	defense response	4.215324e-5
GO:0009448	gamma-aminobutyric acid metabolic process	4.246953e-5
GO:2000484	positive regulation of interleukin-8 secretion	4.246953e-5
GO:0030334	regulation of cell migration	4.296223e-5
GO:0006651	diacylglycerol biosynthetic process	4.583930e-5
GO:0030574	collagen catabolic process	4.604229e-5
GO:0050707	regulation of cytokine secretion	4.673913e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	4.702324e-5
GO:0002741	positive regulation of cytokine secretion involved in immune response	4.758595e-5
GO:0050995	negative regulation of lipid catabolic process	4.871770e-5
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.957454e-5
GO:0034380	high-density lipoprotein particle assembly	4.965373e-5
GO:0002902	regulation of B cell apoptosis	5.060412e-5
GO:0032963	collagen metabolic process	5.067229e-5
GO:0071418	cellular response to amine stimulus	5.165422e-5
GO:0016311	dephosphorylation	5.201896e-5
GO:0042558	pteridine-containing compound metabolic process	5.202799e-5
GO:0019637	organophosphate metabolic process	5.281616e-5
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.289517e-5
GO:0060338	regulation of type I interferon-mediated signaling pathway	5.632151e-5
GO:0006955	immune response	5.748211e-5
GO:0009123	nucleoside monophosphate metabolic process	5.760956e-5
GO:0032602	chemokine production	5.798103e-5
GO:0000072	M phase specific microtubule process	5.816532e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.908739e-5
GO:0032375	negative regulation of cholesterol transport	6.098089e-5
GO:0046069	cGMP catabolic process	6.477491e-5
GO:0051693	actin filament capping	6.587803e-5
GO:0006575	cellular modified amino acid metabolic process	6.698876e-5
GO:0040017	positive regulation of locomotion	6.716936e-5
GO:0008637	apoptotic mitochondrial changes	7.129587e-5
GO:0010863	positive regulation of phospholipase C activity	7.341779e-5
GO:0033598	mammary gland epithelial cell proliferation	7.438555e-5
GO:0051084	'de novo' posttranslational protein folding	7.489175e-5
GO:2000145	regulation of cell motility	7.697217e-5
GO:0019216	regulation of lipid metabolic process	7.951865e-5
GO:0032642	regulation of chemokine production	8.122763e-5
GO:0090023	positive regulation of neutrophil chemotaxis	8.377760e-5
GO:0016090	prenol metabolic process	8.436080e-5
GO:0050706	regulation of interleukin-1 beta secretion	8.600110e-5
GO:0006958	complement activation, classical pathway	8.616874e-5
GO:2000273	positive regulation of receptor activity	8.664088e-5
GO:0046688	response to copper ion	8.678521e-5
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	8.868770e-5
GO:0070887	cellular response to chemical stimulus	8.960556e-5
GO:0071230	cellular response to amino acid stimulus	8.963525e-5
GO:0006897	endocytosis	9.172788e-5
GO:0043244	regulation of protein complex disassembly	9.567370e-5
GO:0043627	response to estrogen stimulus	9.655316e-5
GO:0006760	folic acid-containing compound metabolic process	9.657898e-5
GO:2000147	positive regulation of cell motility	9.838595e-5
GO:0050668	positive regulation of homocysteine metabolic process	1.002616e-4
GO:0045963	negative regulation of dopamine metabolic process	1.002616e-4
GO:0035419	activation of MAPK activity involved in innate immune response	1.002616e-4
GO:0015862	uridine transport	1.034434e-4
GO:0006883	cellular sodium ion homeostasis	1.034434e-4
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.066742e-4
GO:0071229	cellular response to acid	1.082801e-4
GO:0051403	stress-activated MAPK cascade	1.103240e-4
GO:0032880	regulation of protein localization	1.123671e-4
GO:0006957	complement activation, alternative pathway	1.146270e-4
GO:2000106	regulation of leukocyte apoptosis	1.150464e-4
GO:0032488	Cdc42 protein signal transduction	1.157568e-4
GO:0032691	negative regulation of interleukin-1 beta production	1.201447e-4
GO:0002237	response to molecule of bacterial origin	1.214146e-4
GO:0002684	positive regulation of immune system process	1.241962e-4
GO:0003073	regulation of systemic arterial blood pressure	1.255723e-4
GO:0061049	cell growth involved in cardiac muscle cell development	1.307288e-4
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	1.307288e-4
GO:0003331	positive regulation of extracellular matrix constituent secretion	1.307288e-4
GO:0008065	establishment of blood-nerve barrier	1.307288e-4
GO:0070309	lens fiber cell morphogenesis	1.349177e-4
GO:0010035	response to inorganic substance	1.386668e-4
GO:0060067	cervix development	1.399839e-4
GO:0046697	decidualization	1.425769e-4
GO:0007202	activation of phospholipase C activity	1.444195e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.469935e-4
GO:0030335	positive regulation of cell migration	1.489541e-4
GO:0048149	behavioral response to ethanol	1.523117e-4
GO:0010193	response to ozone	1.573899e-4
GO:0060191	regulation of lipase activity	1.575362e-4
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.587550e-4
GO:0005979	regulation of glycogen biosynthetic process	1.623735e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1.633741e-4
GO:0009310	amine catabolic process	1.664381e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.672098e-4
GO:0050850	positive regulation of calcium-mediated signaling	1.704822e-4
GO:0045840	positive regulation of mitosis	1.747661e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	1.755567e-4
GO:0050704	regulation of interleukin-1 secretion	1.756762e-4
GO:0042402	cellular biogenic amine catabolic process	1.756762e-4
GO:0001990	regulation of systemic arterial blood pressure by hormone	1.767567e-4
GO:0010518	positive regulation of phospholipase activity	1.789821e-4
GO:0032680	regulation of tumor necrosis factor production	1.832026e-4
GO:0051764	actin crosslink formation	1.844850e-4
GO:0090037	positive regulation of protein kinase C signaling cascade	1.844850e-4
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.844850e-4
GO:0071635	negative regulation of transforming growth factor beta production	1.846163e-4
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	1.854945e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1.876795e-4
GO:0022900	electron transport chain	1.884705e-4
GO:0023052	signaling	1.911162e-4
GO:0042493	response to drug	1.930673e-4
GO:0001300	chronological cell aging	1.959362e-4
GO:0071417	cellular response to organic nitrogen	1.964701e-4
GO:0002250	adaptive immune response	1.991057e-4
GO:0010951	negative regulation of endopeptidase activity	2.003808e-4
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	2.117508e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	2.123131e-4
GO:0051270	regulation of cellular component movement	2.134318e-4
GO:0051657	maintenance of organelle location	2.161409e-4
GO:0090257	regulation of muscle system process	2.179182e-4
GO:0050795	regulation of behavior	2.192825e-4
GO:0070189	kynurenine metabolic process	2.194265e-4
GO:0010873	positive regulation of cholesterol esterification	2.194349e-4
GO:0051488	activation of anaphase-promoting complex activity	2.202018e-4
GO:0009607	response to biotic stimulus	2.250296e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.266461e-4
GO:0050727	regulation of inflammatory response	2.283471e-4
GO:0070229	negative regulation of lymphocyte apoptosis	2.296477e-4
GO:0030837	negative regulation of actin filament polymerization	2.306030e-4
GO:0009617	response to bacterium	2.341221e-4
GO:0045651	positive regulation of macrophage differentiation	2.352599e-4
GO:0006477	protein sulfation	2.364701e-4
GO:0002019	regulation of renal output by angiotensin	2.382624e-4
GO:0032692	negative regulation of interleukin-1 production	2.390378e-4
GO:0070875	positive regulation of glycogen metabolic process	2.436614e-4
GO:0030300	regulation of intestinal cholesterol absorption	2.524548e-4
GO:0071545	inositol phosphate catabolic process	2.569318e-4
GO:0008207	C21-steroid hormone metabolic process	2.591238e-4
GO:0090022	regulation of neutrophil chemotaxis	2.603310e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	2.628987e-4
GO:0043279	response to alkaloid	2.632871e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2.643468e-4
GO:0042177	negative regulation of protein catabolic process	2.648120e-4
GO:0045940	positive regulation of steroid metabolic process	2.683402e-4
GO:0032781	positive regulation of ATPase activity	2.699083e-4
GO:0019374	galactolipid metabolic process	2.710435e-4
GO:0048261	negative regulation of receptor-mediated endocytosis	2.756388e-4
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	2.794884e-4
GO:0071219	cellular response to molecule of bacterial origin	2.806623e-4
GO:0051272	positive regulation of cellular component movement	2.829797e-4
GO:0032677	regulation of interleukin-8 production	2.871896e-4
GO:0010872	regulation of cholesterol esterification	2.924997e-4
GO:0007154	cell communication	2.969669e-4
GO:0001812	positive regulation of type I hypersensitivity	3.003429e-4
GO:0050708	regulation of protein secretion	3.011722e-4
GO:0003218	cardiac left ventricle formation	3.034587e-4
GO:0007290	spermatid nucleus elongation	3.034587e-4
GO:0032649	regulation of interferon-gamma production	3.235993e-4
GO:0072668	tubulin complex biogenesis	3.254922e-4
GO:0071321	cellular response to cGMP	3.272812e-4
GO:0001101	response to acid	3.274197e-4
GO:0046855	inositol phosphate dephosphorylation	3.288479e-4
GO:0006950	response to stress	3.344462e-4
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	3.368904e-4
GO:0051716	cellular response to stimulus	3.501395e-4
GO:0044259	multicellular organismal macromolecule metabolic process	3.505828e-4
GO:0045988	negative regulation of striated muscle contraction	3.515557e-4
GO:0052572	response to host immune response	3.536048e-4
GO:0034097	response to cytokine stimulus	3.540452e-4
GO:0032496	response to lipopolysaccharide	3.619024e-4
GO:0006664	glycolipid metabolic process	3.650100e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	3.723611e-4
GO:0009166	nucleotide catabolic process	3.979682e-4
GO:0001759	organ induction	4.181258e-4
GO:0032227	negative regulation of synaptic transmission, dopaminergic	4.183740e-4
GO:0071495	cellular response to endogenous stimulus	4.258125e-4
GO:0070306	lens fiber cell differentiation	4.383695e-4
GO:0040012	regulation of locomotion	4.432016e-4
GO:0008616	queuosine biosynthetic process	4.451667e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	4.556304e-4
GO:0046700	heterocycle catabolic process	4.563072e-4
GO:0007165	signal transduction	4.583134e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	4.650010e-4
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	4.711188e-4
GO:0060341	regulation of cellular localization	4.744899e-4
GO:0046456	icosanoid biosynthetic process	4.790811e-4
GO:0044270	cellular nitrogen compound catabolic process	4.823993e-4
GO:0051646	mitochondrion localization	4.837474e-4
GO:0002339	B cell selection	4.908437e-4
GO:0051964	negative regulation of synapse assembly	4.908437e-4
GO:0031272	regulation of pseudopodium assembly	5.329460e-4
GO:0051055	negative regulation of lipid biosynthetic process	5.431280e-4
GO:0043086	negative regulation of catalytic activity	5.463916e-4
GO:0031915	positive regulation of synaptic plasticity	5.731044e-4
GO:0032930	positive regulation of superoxide anion generation	5.770351e-4
GO:0035150	regulation of tube size	5.803851e-4
GO:0006956	complement activation	5.877960e-4
GO:0042306	regulation of protein import into nucleus	5.884065e-4
GO:0050710	negative regulation of cytokine secretion	6.101750e-4
GO:0019058	viral infectious cycle	6.101750e-4
GO:0044058	regulation of digestive system process	6.110304e-4
GO:0006470	protein dephosphorylation	6.169432e-4
GO:0090076	relaxation of skeletal muscle	6.221990e-4
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	6.221990e-4
GO:0010948	negative regulation of cell cycle process	6.302981e-4
GO:0035556	intracellular signal transduction	6.307078e-4
GO:0051659	maintenance of mitochondrion location	6.308386e-4
GO:0051386	regulation of nerve growth factor receptor signaling pathway	6.346835e-4
GO:0048584	positive regulation of response to stimulus	6.392546e-4
GO:0008286	insulin receptor signaling pathway	6.517897e-4
GO:0010243	response to organic nitrogen	6.522093e-4
GO:0071216	cellular response to biotic stimulus	6.547275e-4
GO:0035813	regulation of renal sodium excretion	6.567800e-4
GO:0030162	regulation of proteolysis	6.578224e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	6.601090e-4
GO:2000647	negative regulation of stem cell proliferation	6.645502e-4
GO:0070563	negative regulation of vitamin D receptor signaling pathway	6.645502e-4
GO:0035921	desmosome disassembly	6.645502e-4
GO:0010839	negative regulation of keratinocyte proliferation	6.645502e-4
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	6.652534e-4
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	6.652534e-4
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	6.652534e-4
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	6.652534e-4
GO:0060210	metestrus	6.652534e-4
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	6.652534e-4
GO:0050880	regulation of blood vessel size	6.693825e-4
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	6.758042e-4
GO:0034122	negative regulation of toll-like receptor signaling pathway	6.758042e-4
GO:0050920	regulation of chemotaxis	6.846998e-4
GO:0009063	cellular amino acid catabolic process	6.883235e-4
GO:0045835	negative regulation of meiosis	7.077497e-4
GO:0042104	positive regulation of activated T cell proliferation	7.125669e-4
GO:0009056	catabolic process	7.324852e-4
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	7.349178e-4
GO:0002115	store-operated calcium entry	7.349178e-4
GO:0006690	icosanoid metabolic process	7.351605e-4
GO:0016486	peptide hormone processing	7.356780e-4
GO:0002483	antigen processing and presentation of endogenous peptide antigen	7.368527e-4
GO:0072594	establishment of protein localization to organelle	7.496911e-4
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	7.569057e-4
GO:0060290	transdifferentiation	7.569057e-4
GO:0007092	activation of mitotic anaphase-promoting complex activity	7.569057e-4
GO:0042742	defense response to bacterium	7.593797e-4
GO:0022904	respiratory electron transport chain	7.603914e-4
GO:0072521	purine-containing compound metabolic process	7.688313e-4
GO:0070613	regulation of protein processing	7.801147e-4
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	7.853987e-4
GO:0010985	negative regulation of lipoprotein particle clearance	8.062748e-4
GO:0001932	regulation of protein phosphorylation	8.278151e-4
GO:0006644	phospholipid metabolic process	8.323420e-4
GO:0002700	regulation of production of molecular mediator of immune response	8.569174e-4
GO:0051246	regulation of protein metabolic process	8.715619e-4
GO:0006643	membrane lipid metabolic process	8.873367e-4
GO:0046655	folic acid metabolic process	9.113039e-4
GO:0030198	extracellular matrix organization	9.117150e-4
GO:0032355	response to estradiol stimulus	9.230005e-4
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	9.309542e-4
GO:0022417	protein maturation by protein folding	9.309542e-4
GO:0001835	blastocyst hatching	9.333820e-4
GO:0051494	negative regulation of cytoskeleton organization	9.362749e-4
GO:0061037	negative regulation of cartilage development	9.441561e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	9.653560e-4
GO:0006195	purine nucleotide catabolic process	9.751650e-4
GO:0042345	regulation of NF-kappaB import into nucleus	9.779506e-4
GO:0009629	response to gravity	9.994011e-4
GO:0045047	protein targeting to ER	1.015841e-3
GO:0002697	regulation of immune effector process	1.017161e-3
GO:0006937	regulation of muscle contraction	1.019040e-3
GO:0043434	response to peptide hormone stimulus	1.020516e-3
GO:0019067	viral assembly, maturation, egress, and release	1.021010e-3
GO:0009725	response to hormone stimulus	1.040793e-3
GO:0050790	regulation of catalytic activity	1.053638e-3
GO:0006665	sphingolipid metabolic process	1.064223e-3
GO:0050709	negative regulation of protein secretion	1.068201e-3
GO:0008654	phospholipid biosynthetic process	1.101556e-3
GO:0051222	positive regulation of protein transport	1.104163e-3
GO:0010269	response to selenium ion	1.107889e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	1.110913e-3
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	1.119588e-3
GO:0006620	posttranslational protein targeting to membrane	1.129640e-3
GO:0050776	regulation of immune response	1.134198e-3
GO:0050878	regulation of body fluid levels	1.147059e-3
GO:0035335	peptidyl-tyrosine dephosphorylation	1.147570e-3
GO:0032908	regulation of transforming growth factor beta1 production	1.155132e-3
GO:0002526	acute inflammatory response	1.168459e-3
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.175390e-3
GO:0045471	response to ethanol	1.180792e-3
GO:0001736	establishment of planar polarity	1.215100e-3
GO:0002540	leukotriene production involved in inflammatory response	1.233736e-3
GO:0046340	diacylglycerol catabolic process	1.246418e-3
GO:0051592	response to calcium ion	1.248681e-3
GO:0051961	negative regulation of nervous system development	1.251990e-3
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.258192e-3
GO:0001935	endothelial cell proliferation	1.263260e-3
GO:0072539	T-helper 17 cell differentiation	1.266125e-3
GO:0032661	regulation of interleukin-18 production	1.266125e-3
GO:0006083	acetate metabolic process	1.266125e-3
GO:0045446	endothelial cell differentiation	1.271883e-3
GO:0010761	fibroblast migration	1.275846e-3
GO:0046466	membrane lipid catabolic process	1.284663e-3
GO:0032459	regulation of protein oligomerization	1.284663e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.294351e-3
GO:0006672	ceramide metabolic process	1.338494e-3
GO:0090066	regulation of anatomical structure size	1.347114e-3
GO:0060591	chondroblast differentiation	1.368536e-3
GO:0051896	regulation of protein kinase B signaling cascade	1.399624e-3
GO:0043200	response to amino acid stimulus	1.403171e-3
GO:0071363	cellular response to growth factor stimulus	1.407836e-3
GO:0046006	regulation of activated T cell proliferation	1.408346e-3
GO:0051135	positive regulation of NK T cell activation	1.412596e-3
GO:0071634	regulation of transforming growth factor beta production	1.434114e-3
GO:0042840	D-glucuronate catabolic process	1.498301e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.498301e-3
GO:0003096	renal sodium ion transport	1.498301e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.498301e-3
GO:0032782	bile acid secretion	1.498301e-3
GO:0032387	negative regulation of intracellular transport	1.500730e-3
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.509610e-3
GO:0042396	phosphagen biosynthetic process	1.516297e-3
GO:0022415	viral reproductive process	1.520113e-3
GO:0060068	vagina development	1.524389e-3
GO:0009628	response to abiotic stimulus	1.534246e-3
GO:0046686	response to cadmium ion	1.536178e-3
GO:0050810	regulation of steroid biosynthetic process	1.544024e-3
GO:0006406	mRNA export from nucleus	1.544941e-3
GO:0070340	detection of bacterial lipopeptide	1.571794e-3
GO:0002828	regulation of type 2 immune response	1.596317e-3
GO:0006568	tryptophan metabolic process	1.613541e-3
GO:0034382	chylomicron remnant clearance	1.630823e-3
GO:0010639	negative regulation of organelle organization	1.632132e-3
GO:0034377	plasma lipoprotein particle assembly	1.634632e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	1.642024e-3
GO:0001516	prostaglandin biosynthetic process	1.644713e-3
GO:2001021	negative regulation of response to DNA damage stimulus	1.644858e-3
GO:0031017	exocrine pancreas development	1.648618e-3
GO:0015802	basic amino acid transport	1.667064e-3
GO:0032425	positive regulation of mismatch repair	1.700619e-3
GO:0051451	myoblast migration	1.700619e-3
GO:0010912	positive regulation of isomerase activity	1.700619e-3
GO:0006939	smooth muscle contraction	1.715482e-3
GO:0031274	positive regulation of pseudopodium assembly	1.725730e-3
GO:2000146	negative regulation of cell motility	1.739030e-3
GO:0032501	multicellular organismal process	1.759366e-3
GO:0051461	positive regulation of corticotropin secretion	1.766611e-3
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	1.766611e-3
GO:0051445	regulation of meiotic cell cycle	1.791546e-3
GO:0070305	response to cGMP	1.796746e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.796746e-3
GO:0009071	serine family amino acid catabolic process	1.807905e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1.813170e-3
GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	1.813170e-3
GO:0002275	myeloid cell activation involved in immune response	1.818575e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.824425e-3
GO:0002885	positive regulation of hypersensitivity	1.824425e-3
GO:0019441	tryptophan catabolic process to kynurenine	1.826220e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	1.831918e-3
GO:0002675	positive regulation of acute inflammatory response	1.858211e-3
GO:0010565	regulation of cellular ketone metabolic process	1.876758e-3
GO:0032012	regulation of ARF protein signal transduction	1.885858e-3
GO:0006163	purine nucleotide metabolic process	1.893303e-3
GO:0006986	response to unfolded protein	1.896208e-3
GO:0050994	regulation of lipid catabolic process	1.919489e-3
GO:0001798	positive regulation of type IIa hypersensitivity	1.926581e-3
GO:0009450	gamma-aminobutyric acid catabolic process	1.934948e-3
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.934948e-3
GO:0061077	chaperone-mediated protein folding	1.978819e-3
GO:0006693	prostaglandin metabolic process	1.989575e-3
GO:0034109	homotypic cell-cell adhesion	2.029474e-3
GO:0070972	protein localization in endoplasmic reticulum	2.055633e-3
GO:0052556	positive regulation by symbiont of host immune response	2.083748e-3
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	2.083748e-3
GO:0052509	positive regulation by symbiont of host defense response	2.083748e-3