Novel motif:114

name:	motif114_AAACCCGCTC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	5.043476e-10
GO:0006183	GTP biosynthetic process	7.566706e-10
GO:0006228	UTP biosynthetic process	7.566706e-10
GO:0006165	nucleoside diphosphate phosphorylation	7.566706e-10
GO:0048103	somatic stem cell division	1.115225e-9
GO:0006241	CTP biosynthetic process	3.794413e-9
GO:0043503	skeletal muscle fiber adaptation	5.502611e-9
GO:0021869	forebrain ventricular zone progenitor cell division	9.088836e-9
GO:0090304	nucleic acid metabolic process	1.853448e-8
GO:0010717	regulation of epithelial to mesenchymal transition	4.266464e-8
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.785732e-8
GO:0016070	RNA metabolic process	8.260232e-8
GO:0050434	positive regulation of viral transcription	8.303486e-8
GO:0021873	forebrain neuroblast division	9.084338e-8
GO:0017145	stem cell division	1.811902e-7
GO:0043923	positive regulation by host of viral transcription	2.009256e-7
GO:0045063	T-helper 1 cell differentiation	3.935831e-7
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	4.722407e-7
GO:0006333	chromatin assembly or disassembly	5.646303e-7
GO:0006310	DNA recombination	5.843875e-7
GO:0070670	response to interleukin-4	6.044995e-7
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	6.050251e-7
GO:0009589	detection of UV	6.050251e-7
GO:0000088	mitotic prophase	6.050251e-7
GO:0021847	ventricular zone neuroblast division	8.475958e-7
GO:0035425	autocrine signaling	9.238445e-7
GO:0071353	cellular response to interleukin-4	1.196672e-6
GO:0046782	regulation of viral transcription	1.217041e-6
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.481572e-6
GO:0006383	transcription from RNA polymerase III promoter	1.843573e-6
GO:0006139	nucleobase-containing compound metabolic process	2.658640e-6
GO:0042797	tRNA transcription from RNA polymerase III promoter	2.942823e-6
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	2.942823e-6
GO:0030223	neutrophil differentiation	3.009900e-6
GO:0042696	menarche	3.070340e-6
GO:0060689	cell differentiation involved in salivary gland development	3.311960e-6
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.703495e-6
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	3.830943e-6
GO:0009267	cellular response to starvation	4.036174e-6
GO:0060732	positive regulation of inositol phosphate biosynthetic process	4.751971e-6
GO:0048524	positive regulation of viral reproduction	4.802565e-6
GO:0030490	maturation of SSU-rRNA	4.983482e-6
GO:0000079	regulation of cyclin-dependent protein kinase activity	6.435380e-6
GO:0042274	ribosomal small subunit biogenesis	6.448501e-6
GO:0021569	rhombomere 3 development	6.464777e-6
GO:0031497	chromatin assembly	6.681856e-6
GO:0009303	rRNA transcription	6.957614e-6
GO:0006396	RNA processing	6.961186e-6
GO:0034728	nucleosome organization	7.206251e-6
GO:0071866	negative regulation of apoptosis in bone marrow	7.499162e-6
GO:0071864	positive regulation of cell proliferation in bone marrow	7.499162e-6
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	7.540610e-6
GO:0001662	behavioral fear response	7.635523e-6
GO:0021759	globus pallidus development	7.766301e-6
GO:0001963	synaptic transmission, dopaminergic	7.772942e-6
GO:0030683	evasion by virus of host immune response	8.257824e-6
GO:0071895	odontoblast differentiation	8.302244e-6
GO:0016072	rRNA metabolic process	8.525958e-6
GO:0032784	regulation of transcription elongation, DNA-dependent	9.097997e-6
GO:0009132	nucleoside diphosphate metabolic process	9.372720e-6
GO:0042254	ribosome biogenesis	9.724752e-6
GO:0033153	T cell receptor V(D)J recombination	1.136503e-5
GO:0002209	behavioral defense response	1.242352e-5
GO:0042596	fear response	1.258180e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.315732e-5
GO:2000243	positive regulation of reproductive process	1.317477e-5
GO:0006354	transcription elongation, DNA-dependent	1.320310e-5
GO:0006353	transcription termination, DNA-dependent	1.458904e-5
GO:0071105	response to interleukin-11	1.542948e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.542948e-5
GO:0023035	CD40 signaling pathway	1.542948e-5
GO:0006517	protein deglycosylation	1.819964e-5
GO:0010467	gene expression	1.848014e-5
GO:0006364	rRNA processing	1.901056e-5
GO:0043501	skeletal muscle adaptation	1.937357e-5
GO:0042255	ribosome assembly	1.970409e-5
GO:0030327	prenylated protein catabolic process	2.028781e-5
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2.046775e-5
GO:0006220	pyrimidine nucleotide metabolic process	2.075394e-5
GO:0033151	V(D)J recombination	2.153488e-5
GO:0006261	DNA-dependent DNA replication	2.351699e-5
GO:0005984	disaccharide metabolic process	2.506819e-5
GO:0009304	tRNA transcription	2.669499e-5
GO:0044342	type B pancreatic cell proliferation	2.705968e-5
GO:0010918	positive regulation of mitochondrial membrane potential	2.705968e-5
GO:0043921	modulation by host of viral transcription	2.745676e-5
GO:0060631	regulation of meiosis I	2.766317e-5
GO:0000710	meiotic mismatch repair	2.766317e-5
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	2.776249e-5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.417601e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	3.837951e-5
GO:0060112	generation of ovulation cycle rhythm	4.132193e-5
GO:0046755	non-lytic virus budding	4.580707e-5
GO:0042416	dopamine biosynthetic process	4.819180e-5
GO:0031669	cellular response to nutrient levels	4.822524e-5
GO:0071824	protein-DNA complex subunit organization	4.910502e-5
GO:0005989	lactose biosynthetic process	5.074949e-5
GO:0034470	ncRNA processing	5.379940e-5
GO:0006844	acyl carnitine transport	5.559165e-5
GO:0000738	DNA catabolic process, exonucleolytic	5.620375e-5
GO:0006351	transcription, DNA-dependent	5.971432e-5
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	6.116477e-5
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	6.116477e-5
GO:0010836	negative regulation of protein ADP-ribosylation	6.116477e-5
GO:0061153	trachea gland development	6.246491e-5
GO:0032696	negative regulation of interleukin-13 production	6.631180e-5
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	7.072495e-5
GO:0033235	positive regulation of protein sumoylation	7.135367e-5
GO:0021872	forebrain generation of neurons	7.465640e-5
GO:0001957	intramembranous ossification	7.473236e-5
GO:0002200	somatic diversification of immune receptors	7.546971e-5
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	7.691215e-5
GO:0097039	protein linear polyubiquitination	7.822371e-5
GO:0016558	protein import into peroxisome matrix	8.173541e-5
GO:0032774	RNA biosynthetic process	8.403106e-5
GO:0006515	misfolded or incompletely synthesized protein catabolic process	8.871402e-5
GO:0014888	striated muscle adaptation	9.279806e-5
GO:0007339	binding of sperm to zona pellucida	9.470322e-5
GO:0000724	double-strand break repair via homologous recombination	9.772064e-5
GO:0070327	thyroid hormone transport	1.083939e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	1.156174e-4
GO:0010226	response to lithium ion	1.235310e-4
GO:0042093	T-helper cell differentiation	1.238280e-4
GO:0006334	nucleosome assembly	1.258726e-4
GO:0034645	cellular macromolecule biosynthetic process	1.269868e-4
GO:0009062	fatty acid catabolic process	1.274629e-4
GO:0009451	RNA modification	1.278480e-4
GO:0006311	meiotic gene conversion	1.319967e-4
GO:0045128	negative regulation of reciprocal meiotic recombination	1.319967e-4
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	1.388641e-4
GO:0006284	base-excision repair	1.394419e-4
GO:0000725	recombinational repair	1.397994e-4
GO:0019054	modulation by virus of host cellular process	1.412198e-4
GO:0010520	regulation of reciprocal meiotic recombination	1.426129e-4
GO:0000028	ribosomal small subunit assembly	1.470851e-4
GO:0072528	pyrimidine-containing compound biosynthetic process	1.536993e-4
GO:0060253	negative regulation of glial cell proliferation	1.569308e-4
GO:0042538	hyperosmotic salinity response	1.584018e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.643688e-4
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	1.659835e-4
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.659835e-4
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	1.659835e-4
GO:0006853	carnitine shuttle	1.682936e-4
GO:0030157	pancreatic juice secretion	1.693288e-4
GO:0006972	hyperosmotic response	1.882028e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	1.938884e-4
GO:0006012	galactose metabolic process	1.947475e-4
GO:0042594	response to starvation	1.966907e-4
GO:0042423	catecholamine biosynthetic process	1.983394e-4
GO:0060968	regulation of gene silencing	2.038849e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	2.148731e-4
GO:0031123	RNA 3'-end processing	2.193190e-4
GO:0022613	ribonucleoprotein complex biogenesis	2.346675e-4
GO:0043949	regulation of cAMP-mediated signaling	2.388044e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.394246e-4
GO:0071218	cellular response to misfolded protein	2.422774e-4
GO:0072329	monocarboxylic acid catabolic process	2.500252e-4
GO:0009059	macromolecule biosynthetic process	2.534205e-4
GO:0051096	positive regulation of helicase activity	2.613494e-4
GO:0007099	centriole replication	2.613494e-4
GO:0021943	formation of radial glial scaffolds	2.746294e-4
GO:0007127	meiosis I	2.770405e-4
GO:0051095	regulation of helicase activity	2.914334e-4
GO:0000729	DNA double-strand break processing	2.914334e-4
GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	2.947650e-4
GO:0032714	negative regulation of interleukin-5 production	3.013182e-4
GO:0032916	positive regulation of transforming growth factor beta3 production	3.021670e-4
GO:0044258	intestinal lipid catabolic process	3.047256e-4
GO:0018350	protein esterification	3.047256e-4
GO:0006583	melanin biosynthetic process from tyrosine	3.070825e-4
GO:0060346	bone trabecula formation	3.164348e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	3.252174e-4
GO:0006363	termination of RNA polymerase I transcription	3.291399e-4
GO:0061099	negative regulation of protein tyrosine kinase activity	3.293995e-4
GO:0080009	mRNA methylation	3.614190e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	3.614190e-4
GO:0006221	pyrimidine nucleotide biosynthetic process	3.785421e-4
GO:0034976	response to endoplasmic reticulum stress	3.788925e-4
GO:0051320	S phase	3.808552e-4
GO:0048488	synaptic vesicle endocytosis	3.844358e-4
GO:0006352	transcription initiation, DNA-dependent	3.865805e-4
GO:0006545	glycine biosynthetic process	4.008037e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	4.037579e-4
GO:0045838	positive regulation of membrane potential	4.394494e-4
GO:0006271	DNA strand elongation involved in DNA replication	4.408995e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	4.627776e-4
GO:0007501	mesodermal cell fate specification	4.653836e-4
GO:0006635	fatty acid beta-oxidation	4.750129e-4
GO:0000375	RNA splicing, via transesterification reactions	5.057913e-4
GO:0016476	regulation of embryonic cell shape	5.187254e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	5.261612e-4
GO:0065004	protein-DNA complex assembly	5.738460e-4
GO:0002286	T cell activation involved in immune response	5.775935e-4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	5.875594e-4
GO:0046939	nucleotide phosphorylation	6.027709e-4
GO:2000974	negative regulation of pro-B cell differentiation	6.059564e-4
GO:0060154	cellular process regulating host cell cycle in response to virus	6.179394e-4
GO:0019264	glycine biosynthetic process from serine	6.182387e-4
GO:0070672	response to interleukin-15	6.316721e-4
GO:0060828	regulation of canonical Wnt receptor signaling pathway	6.373975e-4
GO:0048619	embryonic hindgut morphogenesis	6.502019e-4
GO:0008334	histone mRNA metabolic process	6.516131e-4
GO:0071312	cellular response to alkaloid	6.563270e-4
GO:0038003	opioid receptor signaling pathway	6.563270e-4
GO:0050792	regulation of viral reproduction	6.669313e-4
GO:0035344	hypoxanthine transport	6.713843e-4
GO:0035364	thymine transport	6.713843e-4
GO:0021528	commissural neuron differentiation in spinal cord	6.713843e-4
GO:0015854	guanine transport	6.713843e-4
GO:0035036	sperm-egg recognition	6.718039e-4
GO:0009218	pyrimidine ribonucleotide metabolic process	6.987367e-4
GO:0071480	cellular response to gamma radiation	7.050010e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	7.079616e-4
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	7.099294e-4
GO:0043570	maintenance of DNA repeat elements	7.128470e-4
GO:0042149	cellular response to glucose starvation	7.129874e-4
GO:0015858	nucleoside transport	7.202428e-4
GO:0006360	transcription from RNA polymerase I promoter	7.748107e-4
GO:0033314	mitotic cell cycle DNA replication checkpoint	7.807528e-4
GO:0071044	histone mRNA catabolic process	7.994838e-4
GO:0006367	transcription initiation from RNA polymerase II promoter	8.048859e-4
GO:0006288	base-excision repair, DNA ligation	8.229275e-4
GO:0072229	metanephric proximal convoluted tubule development	8.239294e-4
GO:0042840	D-glucuronate catabolic process	8.239294e-4
GO:0045404	positive regulation of interleukin-4 biosynthetic process	8.283943e-4
GO:0021546	rhombomere development	8.594876e-4
GO:0034198	cellular response to amino acid starvation	8.616954e-4
GO:0031591	wybutosine biosynthetic process	8.711313e-4
GO:0006369	termination of RNA polymerase II transcription	8.990858e-4
GO:0006359	regulation of transcription from RNA polymerase III promoter	9.175313e-4
GO:0034641	cellular nitrogen compound metabolic process	9.190338e-4
GO:0031297	replication fork processing	9.354521e-4
GO:0090181	regulation of cholesterol metabolic process	9.611626e-4
GO:0032656	regulation of interleukin-13 production	1.035485e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.050595e-3
GO:0033233	regulation of protein sumoylation	1.058660e-3
GO:0048069	eye pigmentation	1.094834e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.117750e-3
GO:0006438	valyl-tRNA aminoacylation	1.137713e-3
GO:0071843	cellular component biogenesis at cellular level	1.142829e-3
GO:0000154	rRNA modification	1.171981e-3
GO:0032201	telomere maintenance via semi-conservative replication	1.207074e-3
GO:0008634	negative regulation of survival gene product expression	1.208375e-3
GO:0090399	replicative senescence	1.210300e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	1.210772e-3
GO:0043181	vacuolar sequestering	1.210772e-3
GO:0005985	sucrose metabolic process	1.210772e-3
GO:0000023	maltose metabolic process	1.210772e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	1.226477e-3
GO:0034505	tooth mineralization	1.247844e-3
GO:0006478	peptidyl-tyrosine sulfation	1.249197e-3
GO:0061084	negative regulation of protein refolding	1.255845e-3
GO:0007569	cell aging	1.283523e-3
GO:0042474	middle ear morphogenesis	1.293103e-3
GO:0070861	regulation of protein exit from endoplasmic reticulum	1.296213e-3
GO:0034660	ncRNA metabolic process	1.309432e-3
GO:0044068	modulation by symbiont of host cellular process	1.322877e-3
GO:0006281	DNA repair	1.325268e-3
GO:0006301	postreplication repair	1.342367e-3
GO:0042417	dopamine metabolic process	1.373124e-3
GO:0040030	regulation of molecular function, epigenetic	1.376957e-3
GO:0021570	rhombomere 4 development	1.376957e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	1.470422e-3
GO:0021658	rhombomere 3 morphogenesis	1.491314e-3
GO:0043574	peroxisomal transport	1.541320e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	1.555780e-3
GO:0006913	nucleocytoplasmic transport	1.607379e-3
GO:0010833	telomere maintenance via telomere lengthening	1.660816e-3
GO:0022616	DNA strand elongation	1.720684e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	1.751901e-3
GO:0090042	tubulin deacetylation	1.772221e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.772221e-3
GO:0070846	Hsp90 deacetylation	1.772221e-3
GO:0060209	estrus	1.772221e-3
GO:0030047	actin modification	1.772221e-3
GO:0032910	regulation of transforming growth factor beta3 production	1.820257e-3
GO:0032425	positive regulation of mismatch repair	1.839404e-3
GO:0001842	neural fold formation	1.839404e-3
GO:0061360	optic chiasma development	1.870736e-3
GO:2000597	positive regulation of optic nerve formation	1.870736e-3
GO:0035799	ureter maturation	1.870736e-3
GO:0021650	vestibulocochlear nerve formation	1.870736e-3
GO:0021633	optic nerve structural organization	1.870736e-3
GO:0032202	telomere assembly	1.879526e-3
GO:0051169	nuclear transport	1.884243e-3
GO:0010610	regulation of mRNA stability involved in response to stress	1.911710e-3
GO:0051725	protein de-ADP-ribosylation	1.946868e-3
GO:0030902	hindbrain development	1.978462e-3
GO:0001510	RNA methylation	2.004544e-3
GO:0048240	sperm capacitation	2.018279e-3
GO:0016561	protein import into peroxisome matrix, translocation	2.028104e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	2.041622e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.125187e-3
GO:0014707	branchiomeric skeletal muscle development	2.125187e-3
GO:0071899	negative regulation of estrogen receptor binding	2.132932e-3
GO:0070208	protein heterotrimerization	2.152141e-3
GO:2000241	regulation of reproductive process	2.153437e-3
GO:0006376	mRNA splice site selection	2.200120e-3
GO:0007405	neuroblast proliferation	2.238537e-3
GO:0060623	regulation of chromosome condensation	2.243221e-3
GO:0071283	cellular response to iron(III) ion	2.243221e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	2.243221e-3
GO:0046680	response to DDT	2.243221e-3
GO:0046380	N-acetylneuraminate biosynthetic process	2.243221e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	2.256113e-3
GO:0048625	myoblast cell fate commitment	2.258252e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.284246e-3
GO:0000722	telomere maintenance via recombination	2.295303e-3
GO:0016556	mRNA modification	2.301304e-3
GO:0015864	pyrimidine nucleoside transport	2.306363e-3
GO:0034504	protein localization to nucleus	2.311998e-3
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	2.454689e-3
GO:0006584	catecholamine metabolic process	2.506904e-3
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	2.519726e-3
GO:0000185	activation of MAPKKK activity	2.535495e-3
GO:0021861	forebrain radial glial cell differentiation	2.569500e-3
GO:0070278	extracellular matrix constituent secretion	2.608883e-3
GO:0010260	organ senescence	2.608883e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	2.686759e-3
GO:0006268	DNA unwinding involved in replication	2.711916e-3
GO:0034059	response to anoxia	2.711916e-3
GO:0048305	immunoglobulin secretion	2.714797e-3
GO:0034224	cellular response to zinc ion starvation	2.816747e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2.846501e-3
GO:0032674	regulation of interleukin-5 production	2.848825e-3
GO:0046501	protoporphyrinogen IX metabolic process	2.865589e-3
GO:0002331	pre-B cell allelic exclusion	2.865589e-3
GO:0045402	regulation of interleukin-4 biosynthetic process	2.942687e-3
GO:0009712	catechol-containing compound metabolic process	2.966266e-3
GO:0043484	regulation of RNA splicing	2.979218e-3
GO:0051298	centrosome duplication	2.982876e-3
GO:0010948	negative regulation of cell cycle process	3.085779e-3
GO:0021986	habenula development	3.092769e-3
GO:0006659	phosphatidylserine biosynthetic process	3.152482e-3
GO:0060343	trabecula formation	3.154242e-3
GO:0031282	regulation of guanylate cyclase activity	3.178960e-3
GO:0021932	hindbrain radial glia guided cell migration	3.201215e-3
GO:0043048	dolichyl monophosphate biosynthetic process	3.205905e-3
GO:0003084	positive regulation of systemic arterial blood pressure	3.289162e-3
GO:0060406	positive regulation of penile erection	3.321154e-3
GO:2000465	regulation of glycogen (starch) synthase activity	3.345988e-3
GO:0006013	mannose metabolic process	3.355507e-3
GO:0032606	type I interferon production	3.430470e-3
GO:0031848	protection from non-homologous end joining at telomere	3.550225e-3
GO:0021612	facial nerve structural organization	3.550225e-3
GO:0021536	diencephalon development	3.570605e-3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3.577903e-3
GO:0042668	auditory receptor cell fate determination	3.632334e-3
GO:0010002	cardioblast differentiation	3.632334e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	3.762536e-3
GO:0043388	positive regulation of DNA binding	3.864831e-3
GO:0090085	regulation of protein deubiquitination	3.867338e-3
GO:0071174	mitotic cell cycle spindle checkpoint	3.868901e-3
GO:0030538	embryonic genitalia morphogenesis	3.879002e-3
GO:0032964	collagen biosynthetic process	3.912315e-3
GO:0031668	cellular response to extracellular stimulus	3.957520e-3
GO:0051851	modification by host of symbiont morphology or physiology	4.011003e-3
GO:0043316	cytotoxic T cell degranulation	4.016723e-3
GO:0019478	D-amino acid catabolic process	4.016723e-3
GO:0010986	positive regulation of lipoprotein particle clearance	4.016723e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	4.087687e-3
GO:0030903	notochord development	4.108249e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	4.108249e-3
GO:2000272	negative regulation of receptor activity	4.119758e-3
GO:0072661	protein targeting to plasma membrane	4.157137e-3
GO:0051788	response to misfolded protein	4.172742e-3
GO:0031125	rRNA 3'-end processing	4.312696e-3
GO:0043163	cell envelope organization	4.312696e-3
GO:0021568	rhombomere 2 development	4.312696e-3
GO:0043588	skin development	4.321156e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.340214e-3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.343744e-3
GO:0021983	pituitary gland development	4.391683e-3
GO:0031953	negative regulation of protein autophosphorylation	4.408346e-3
GO:0021535	cell migration in hindbrain	4.408346e-3
GO:0006625	protein targeting to peroxisome	4.430288e-3
GO:0051252	regulation of RNA metabolic process	4.454170e-3
GO:0051726	regulation of cell cycle	4.549618e-3
GO:0070198	protein localization to chromosome, telomeric region	4.553297e-3
GO:0033133	positive regulation of glucokinase activity	4.622475e-3
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	4.622475e-3
GO:0002693	positive regulation of cellular extravasation	4.622475e-3
GO:0071333	cellular response to glucose stimulus	4.697331e-3
GO:0071104	response to interleukin-9	4.816329e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	4.816329e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	4.909810e-3
GO:0032075	positive regulation of nuclease activity	4.918373e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	4.943801e-3
GO:0009312	oligosaccharide biosynthetic process	5.020215e-3
GO:0045839	negative regulation of mitosis	5.044100e-3
GO:0016574	histone ubiquitination	5.047839e-3
GO:0050812	regulation of acyl-CoA biosynthetic process	5.228579e-3
GO:0051622	negative regulation of norepinephrine uptake	5.228579e-3
GO:0070495	negative regulation of thrombin receptor signaling pathway	5.228579e-3
GO:0051585	negative regulation of dopamine uptake	5.228579e-3
GO:0061383	trabecula morphogenesis	5.250341e-3
GO:0050850	positive regulation of calcium-mediated signaling	5.303743e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	5.318006e-3
GO:0005983	starch catabolic process	5.318006e-3
GO:0010524	positive regulation of calcium ion transport into cytosol	5.391779e-3
GO:0030901	midbrain development	5.447531e-3
GO:0043628	ncRNA 3'-end processing	5.519664e-3
GO:0009912	auditory receptor cell fate commitment	5.529556e-3
GO:0060384	innervation	5.565094e-3
GO:0010919	regulation of inositol phosphate biosynthetic process	5.565094e-3
GO:0015680	intracellular copper ion transport	5.566959e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	5.566959e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	5.572231e-3
GO:0035470	positive regulation of vascular wound healing	5.575168e-3
GO:0045540	regulation of cholesterol biosynthetic process	5.634007e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	5.652068e-3
GO:0072162	metanephric mesenchymal cell differentiation	5.653443e-3
GO:0021764	amygdala development	5.714298e-3
GO:0001731	formation of translation preinitiation complex	5.714298e-3
GO:0043922	negative regulation by host of viral transcription	5.757138e-3
GO:0031577	spindle checkpoint	5.861614e-3
GO:0021562	vestibulocochlear nerve development	5.862554e-3
GO:0007379	segment specification	5.867320e-3
GO:0072179	nephric duct formation	5.924020e-3
GO:0002456	T cell mediated immunity	5.975124e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	6.019164e-3
GO:0002691	regulation of cellular extravasation	6.100796e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	6.309826e-3
GO:0090398	cellular senescence	6.360924e-3
GO:0006298	mismatch repair	6.427151e-3
GO:0051103	DNA ligation involved in DNA repair	6.486059e-3
GO:0007144	female meiosis I	6.492299e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	6.501662e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	6.515778e-3
GO:0072527	pyrimidine-containing compound metabolic process	6.537469e-3
GO:0070318	positive regulation of G0 to G1 transition	6.550640e-3
GO:0045351	type I interferon biosynthetic process	6.616576e-3
GO:0006477	protein sulfation	6.623575e-3
GO:2000179	positive regulation of neural precursor cell proliferation	6.832001e-3
GO:0030111	regulation of Wnt receptor signaling pathway	6.955972e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	6.956609e-3
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	6.956609e-3
GO:0021879	forebrain neuron differentiation	7.008401e-3
GO:0071872	cellular response to epinephrine stimulus	7.059472e-3
GO:0033120	positive regulation of RNA splicing	7.093896e-3
GO:0033091	positive regulation of immature T cell proliferation	7.093896e-3
GO:0009298	GDP-mannose biosynthetic process	7.124428e-3
GO:0021506	anterior neuropore closure	7.177194e-3
GO:0003085	negative regulation of systemic arterial blood pressure	7.346500e-3
GO:0045022	early endosome to late endosome transport	7.346500e-3
GO:0006337	nucleosome disassembly	7.369708e-3
GO:0090086	negative regulation of protein deubiquitination	7.461870e-3
GO:0046416	D-amino acid metabolic process	7.461870e-3
GO:0031167	rRNA methylation	7.520505e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	7.524517e-3
GO:0030302	deoxynucleotide transport	7.524517e-3
GO:0009142	nucleoside triphosphate biosynthetic process	7.527864e-3
GO:0014061	regulation of norepinephrine secretion	7.618573e-3
GO:0060996	dendritic spine development	7.618573e-3
GO:0009988	cell-cell recognition	7.703345e-3
GO:0031573	intra-S DNA damage checkpoint	7.728682e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	7.802052e-3
GO:0006984	ER-nucleus signaling pathway	8.043394e-3
GO:0021783	preganglionic parasympathetic nervous system development	8.164803e-3
GO:0072553	terminal button organization	8.251745e-3
GO:0042732	D-xylose metabolic process	8.251745e-3
GO:0002457	T cell antigen processing and presentation	8.251745e-3
GO:0010477	response to sulfur dioxide	8.251745e-3
GO:0007281	germ cell development	8.281028e-3
GO:0033126	positive regulation of GTP catabolic process	8.448221e-3
GO:0046952	ketone body catabolic process	8.588404e-3
GO:0061015	snRNA import into nucleus	8.633449e-3
GO:0018364	peptidyl-glutamine methylation	8.633449e-3
GO:0009311	oligosaccharide metabolic process	8.637818e-3
GO:0002268	follicular dendritic cell differentiation	8.717241e-3
GO:0021557	oculomotor nerve development	8.736879e-3
GO:0009452	RNA capping	8.739358e-3
GO:0006807	nitrogen compound metabolic process	8.752938e-3
GO:0016126	sterol biosynthetic process	8.787230e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	8.928573e-3
GO:0006289	nucleotide-excision repair	8.933360e-3
GO:0006401	RNA catabolic process	9.002016e-3
GO:0006308	DNA catabolic process	9.026709e-3
GO:0032673	regulation of interleukin-4 production	9.033872e-3
GO:0070316	regulation of G0 to G1 transition	9.067511e-3
GO:0000084	S phase of mitotic cell cycle	9.400129e-3
GO:0006397	mRNA processing	9.472898e-3
GO:0002329	pre-B cell differentiation	9.500255e-3
GO:0071496	cellular response to external stimulus	9.539417e-3
GO:0031296	B cell costimulation	9.542773e-3
GO:0021604	cranial nerve structural organization	9.579825e-3
GO:0006302	double-strand break repair	9.601342e-3
GO:0090219	negative regulation of lipid kinase activity	9.708371e-3
GO:0009231	riboflavin biosynthetic process	9.708371e-3
GO:0035330	regulation of hippo signaling cascade	9.863408e-3
GO:0033131	regulation of glucokinase activity	9.867496e-3
GO:0003099	positive regulation of the force of heart contraction by chemical signal	9.939506e-3
GO:0071422	succinate transmembrane transport	9.946979e-3
GO:0019402	galactitol metabolic process	9.946979e-3
GO:0031124	mRNA 3'-end processing	9.951262e-3
GO:0048339	paraxial mesoderm development	9.955962e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	9.997873e-3
GO:0043966	histone H3 acetylation	1.022177e-2
GO:0033083	regulation of immature T cell proliferation	1.023858e-2
GO:0045717	negative regulation of fatty acid biosynthetic process	1.030941e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0033523	histone H2B ubiquitination	1.767675e-8
GO:0008334	histone mRNA metabolic process	4.231401e-8
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	7.849155e-8
GO:0046967	cytosol to ER transport	1.308624e-7
GO:0019060	intracellular transport of viral proteins in host cell	1.308624e-7
GO:0006396	RNA processing	4.063353e-7
GO:0021680	cerebellar Purkinje cell layer development	4.777349e-7
GO:0072259	metanephric interstitial cell development	5.927055e-7
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	5.927055e-7
GO:0072208	metanephric smooth muscle tissue development	5.927055e-7
GO:0072168	specification of anterior mesonephric tubule identity	5.927055e-7
GO:0072184	renal vesicle progenitor cell differentiation	5.927055e-7
GO:0072169	specification of posterior mesonephric tubule identity	5.927055e-7
GO:0072166	posterior mesonephric tubule development	6.309501e-7
GO:0018924	mandelate metabolic process	8.155792e-7
GO:0006398	histone mRNA 3'-end processing	1.017891e-6
GO:0003096	renal sodium ion transport	1.098444e-6
GO:0032782	bile acid secretion	1.098444e-6
GO:0002483	antigen processing and presentation of endogenous peptide antigen	1.102298e-6
GO:0022037	metencephalon development	1.274461e-6
GO:0021695	cerebellar cortex development	1.461039e-6
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.663878e-6
GO:0045083	negative regulation of interleukin-12 biosynthetic process	4.406580e-6
GO:0018158	protein oxidation	5.352039e-6
GO:0010467	gene expression	5.790488e-6
GO:0021549	cerebellum development	5.824891e-6
GO:0051444	negative regulation of ubiquitin-protein ligase activity	6.165291e-6
GO:0008625	induction of apoptosis via death domain receptors	6.762554e-6
GO:0051297	centrosome organization	7.716917e-6
GO:0007052	mitotic spindle organization	9.717490e-6
GO:0060010	Sertoli cell fate commitment	1.199251e-5
GO:0046984	regulation of hemoglobin biosynthetic process	1.273389e-5
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.344999e-5
GO:0021764	amygdala development	1.356696e-5
GO:0031397	negative regulation of protein ubiquitination	1.686414e-5
GO:0043149	stress fiber assembly	1.700176e-5
GO:0090304	nucleic acid metabolic process	1.962269e-5
GO:0045653	negative regulation of megakaryocyte differentiation	2.515939e-5
GO:0048384	retinoic acid receptor signaling pathway	2.523819e-5
GO:0021702	cerebellar Purkinje cell differentiation	2.618986e-5
GO:0018364	peptidyl-glutamine methylation	2.666874e-5
GO:0006930	substrate-dependent cell migration, cell extension	2.666874e-5
GO:0048535	lymph node development	2.865260e-5
GO:0016358	dendrite development	2.868698e-5
GO:0071480	cellular response to gamma radiation	3.348560e-5
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	3.386356e-5
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	3.386356e-5
GO:0032314	regulation of Rac GTPase activity	3.396226e-5
GO:0031023	microtubule organizing center organization	4.476370e-5
GO:2000649	regulation of sodium ion transmembrane transporter activity	4.928276e-5
GO:0061072	iris morphogenesis	4.928276e-5
GO:0002268	follicular dendritic cell differentiation	4.928276e-5
GO:0071777	positive regulation of cell cycle cytokinesis	5.181324e-5
GO:0085020	protein K6-linked ubiquitination	5.927347e-5
GO:0006681	galactosylceramide metabolic process	6.493894e-5
GO:0003218	cardiac left ventricle formation	6.553919e-5
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	7.356577e-5
GO:2000682	positive regulation of rubidium ion transport	7.356577e-5
GO:0001682	tRNA 5'-leader removal	7.356577e-5
GO:0016078	tRNA catabolic process	7.356577e-5
GO:0035826	rubidium ion transport	7.356577e-5
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	7.377969e-5
GO:0015876	acetyl-CoA transport	9.010020e-5
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	9.010020e-5
GO:0016070	RNA metabolic process	1.046783e-4
GO:0080164	regulation of nitric oxide metabolic process	1.267770e-4
GO:0006683	galactosylceramide catabolic process	1.267770e-4
GO:0090003	regulation of establishment of protein localization in plasma membrane	1.271647e-4
GO:0035645	enteric smooth muscle cell differentiation	1.303827e-4
GO:0022616	DNA strand elongation	1.303827e-4
GO:0007497	posterior midgut development	1.303827e-4
GO:0032754	positive regulation of interleukin-5 production	1.365637e-4
GO:0060968	regulation of gene silencing	1.400052e-4
GO:0010939	regulation of necrotic cell death	1.430012e-4
GO:0001886	endothelial cell morphogenesis	1.441929e-4
GO:0071394	cellular response to testosterone stimulus	1.513389e-4
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.608829e-4
GO:0043973	histone H3-K4 acetylation	1.608829e-4
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.608829e-4
GO:0045630	positive regulation of T-helper 2 cell differentiation	1.615874e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.657344e-4
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	1.663834e-4
GO:0043687	post-translational protein modification	1.725135e-4
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.939999e-4
GO:0007051	spindle organization	2.046250e-4
GO:0022403	cell cycle phase	2.217843e-4
GO:2000078	positive regulation of type B pancreatic cell development	2.320052e-4
GO:0006427	histidyl-tRNA aminoacylation	2.347810e-4
GO:0060349	bone morphogenesis	2.485422e-4
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	2.626274e-4
GO:0070831	basement membrane assembly	2.636190e-4
GO:0051967	negative regulation of synaptic transmission, glutamatergic	2.767121e-4
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.831083e-4
GO:0008631	induction of apoptosis by oxidative stress	2.928490e-4
GO:0090307	spindle assembly involved in mitosis	2.931318e-4
GO:0033299	secretion of lysosomal enzymes	2.939280e-4
GO:0006397	mRNA processing	2.998277e-4
GO:0009452	RNA capping	3.296550e-4
GO:0072133	metanephric mesenchyme morphogenesis	3.453216e-4
GO:0008380	RNA splicing	3.495295e-4
GO:0006364	rRNA processing	3.592597e-4
GO:0007099	centriole replication	3.678537e-4
GO:0043523	regulation of neuron apoptosis	3.962137e-4
GO:0072164	mesonephric tubule development	4.012305e-4
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	4.076735e-4
GO:0021697	cerebellar cortex formation	4.274680e-4
GO:0034635	glutathione transport	4.489579e-4
GO:2000381	negative regulation of mesoderm development	5.006442e-4
GO:0006044	N-acetylglucosamine metabolic process	5.685144e-4
GO:0015739	sialic acid transport	5.710437e-4
GO:0010669	epithelial structure maintenance	5.731302e-4
GO:0072162	metanephric mesenchymal cell differentiation	5.900805e-4
GO:0071711	basement membrane organization	5.900805e-4
GO:0016072	rRNA metabolic process	6.032581e-4
GO:0032349	positive regulation of aldosterone biosynthetic process	6.221128e-4
GO:0030221	basophil differentiation	6.221128e-4
GO:0030902	hindbrain development	6.520134e-4
GO:0061032	visceral serous pericardium development	6.533525e-4
GO:0001885	endothelial cell development	6.595459e-4
GO:0006677	glycosylceramide metabolic process	6.995258e-4
GO:0072194	kidney smooth muscle tissue development	7.284451e-4
GO:0016071	mRNA metabolic process	7.388788e-4
GO:0060591	chondroblast differentiation	7.433203e-4
GO:0002118	aggressive behavior	7.433203e-4
GO:0070079	histone H4-R3 demethylation	7.465080e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	7.465080e-4
GO:0070078	histone H3-R2 demethylation	7.465080e-4
GO:0034470	ncRNA processing	7.608110e-4
GO:0060536	cartilage morphogenesis	7.770974e-4
GO:0071044	histone mRNA catabolic process	8.517549e-4
GO:0021801	cerebral cortex radial glia guided migration	8.561701e-4
GO:0030149	sphingolipid catabolic process	9.057178e-4
GO:0072172	mesonephric tubule formation	1.023112e-3
GO:0046514	ceramide catabolic process	1.047907e-3
GO:0002064	epithelial cell development	1.085918e-3
GO:0007144	female meiosis I	1.120034e-3
GO:0009200	deoxyribonucleoside triphosphate metabolic process	1.123522e-3
GO:0000087	M phase of mitotic cell cycle	1.145255e-3
GO:0060547	negative regulation of necrotic cell death	1.151144e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	1.172223e-3
GO:0060122	inner ear receptor stereocilium organization	1.182281e-3
GO:0042335	cuticle development	1.194889e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	1.194889e-3
GO:0035846	oviduct epithelium development	1.194889e-3
GO:0035852	horizontal cell localization	1.194889e-3
GO:0035849	nephric duct elongation	1.194889e-3
GO:0035847	uterine epithelium development	1.194889e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	1.212602e-3
GO:2000505	regulation of energy homeostasis	1.224827e-3
GO:0033690	positive regulation of osteoblast proliferation	1.224827e-3
GO:0031129	inductive cell-cell signaling	1.261963e-3
GO:0007023	post-chaperonin tubulin folding pathway	1.261963e-3
GO:0042311	vasodilation	1.302212e-3
GO:0002209	behavioral defense response	1.312702e-3
GO:2000253	positive regulation of feeding behavior	1.326377e-3
GO:2000507	positive regulation of energy homeostasis	1.326377e-3
GO:0051298	centrosome duplication	1.329777e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.336247e-3
GO:0048389	intermediate mesoderm development	1.336247e-3
GO:0072224	metanephric glomerulus development	1.348232e-3
GO:0042254	ribosome biogenesis	1.392093e-3
GO:0060707	trophoblast giant cell differentiation	1.395154e-3
GO:0072075	metanephric mesenchyme development	1.447923e-3
GO:0035020	regulation of Rac protein signal transduction	1.453138e-3
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1.491637e-3
GO:0021696	cerebellar cortex morphogenesis	1.525606e-3
GO:0071299	cellular response to vitamin A	1.533889e-3
GO:0008361	regulation of cell size	1.552628e-3
GO:0071295	cellular response to vitamin	1.556026e-3
GO:0021766	hippocampus development	1.578068e-3
GO:0000027	ribosomal large subunit assembly	1.593124e-3
GO:0006139	nucleobase-containing compound metabolic process	1.636063e-3
GO:0035307	positive regulation of protein dephosphorylation	1.638178e-3
GO:0002092	positive regulation of receptor internalization	1.667124e-3
GO:0072189	ureter development	1.690032e-3
GO:0044062	regulation of excretion	1.690032e-3
GO:0001539	ciliary or flagellar motility	1.702198e-3
GO:0002678	positive regulation of chronic inflammatory response	1.747716e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.785349e-3
GO:0016264	gap junction assembly	1.785349e-3
GO:0001757	somite specification	1.785349e-3
GO:0071300	cellular response to retinoic acid	1.804975e-3
GO:0000279	M phase	1.824517e-3
GO:0071312	cellular response to alkaloid	1.849381e-3
GO:0006670	sphingosine metabolic process	1.849381e-3
GO:0035306	positive regulation of dephosphorylation	1.849381e-3
GO:0003382	epithelial cell morphogenesis	1.871306e-3
GO:0046477	glycosylceramide catabolic process	1.896346e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.899176e-3
GO:0032736	positive regulation of interleukin-13 production	1.920320e-3
GO:0001662	behavioral fear response	1.943928e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.946287e-3
GO:0007043	cell-cell junction assembly	1.976385e-3
GO:0000278	mitotic cell cycle	2.023865e-3
GO:0030502	negative regulation of bone mineralization	2.026164e-3
GO:0030853	negative regulation of granulocyte differentiation	2.097114e-3
GO:0006613	cotranslational protein targeting to membrane	2.099560e-3
GO:0022007	convergent extension involved in neural plate elongation	2.139536e-3
GO:2000171	negative regulation of dendrite development	2.139536e-3
GO:0051775	response to redox state	2.139546e-3
GO:0032412	regulation of ion transmembrane transporter activity	2.250210e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	2.347402e-3
GO:0003341	cilium movement	2.367873e-3
GO:0046092	deoxycytidine metabolic process	2.397271e-3
GO:0007004	telomere maintenance via telomerase	2.397271e-3
GO:0001510	RNA methylation	2.411193e-3
GO:0032911	negative regulation of transforming growth factor beta1 production	2.444708e-3
GO:0035855	megakaryocyte development	2.531249e-3
GO:0070168	negative regulation of biomineral tissue development	2.559463e-3
GO:0021591	ventricular system development	2.714428e-3
GO:0010842	retina layer formation	2.814989e-3
GO:0072178	nephric duct morphogenesis	2.941422e-3
GO:0021819	layer formation in cerebral cortex	3.026360e-3
GO:0006678	glucosylceramide metabolic process	3.026360e-3
GO:0060285	ciliary cell motility	3.041240e-3
GO:0035802	adrenal cortex formation	3.041240e-3
GO:0060649	mammary gland bud elongation	3.051896e-3
GO:0060659	nipple sheath formation	3.051896e-3
GO:0045210	FasL biosynthetic process	3.051896e-3
GO:0006437	tyrosyl-tRNA aminoacylation	3.051896e-3
GO:0030421	defecation	3.051896e-3
GO:0034421	post-translational protein acetylation	3.051896e-3
GO:0048793	pronephros development	3.179256e-3
GO:0048278	vesicle docking	3.301180e-3
GO:0051782	negative regulation of cell division	3.353125e-3
GO:0046668	regulation of retinal cell programmed cell death	3.357093e-3
GO:0007501	mesodermal cell fate specification	3.357093e-3
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	3.404247e-3
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	3.405004e-3
GO:0021670	lateral ventricle development	3.434893e-3
GO:0032410	negative regulation of transporter activity	3.472804e-3
GO:0021799	cerebral cortex radially oriented cell migration	3.472804e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	3.580715e-3
GO:0010966	regulation of phosphate transport	3.580715e-3
GO:0001964	startle response	3.591385e-3
GO:0002149	hypochlorous acid biosynthetic process	3.594369e-3
GO:0006260	DNA replication	3.620361e-3
GO:0018208	peptidyl-proline modification	3.827810e-3
GO:0051225	spindle assembly	3.841517e-3
GO:0060119	inner ear receptor cell development	3.867006e-3
GO:0072177	mesonephric duct development	3.938248e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3.942190e-3
GO:0034446	substrate adhesion-dependent cell spreading	3.970291e-3
GO:0000413	protein peptidyl-prolyl isomerization	4.035876e-3
GO:0045454	cell redox homeostasis	4.054942e-3
GO:0072141	renal interstitial cell development	4.228773e-3
GO:2000104	negative regulation of DNA-dependent DNA replication	4.278965e-3
GO:0035502	metanephric ureteric bud development	4.399226e-3
GO:0045769	negative regulation of asymmetric cell division	4.399226e-3
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	4.399226e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	4.500716e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	4.500716e-3
GO:0007143	female meiosis	4.500716e-3
GO:0034660	ncRNA metabolic process	4.515453e-3
GO:0032966	negative regulation of collagen biosynthetic process	4.573778e-3
GO:0003326	pancreatic A cell fate commitment	4.573778e-3
GO:0003329	pancreatic PP cell fate commitment	4.573778e-3
GO:0043297	apical junction assembly	4.581382e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	4.671835e-3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	4.702465e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	4.805257e-3
GO:0048246	macrophage chemotaxis	4.805257e-3
GO:0006412	translation	4.839194e-3
GO:0031954	positive regulation of protein autophosphorylation	4.850046e-3
GO:0072284	metanephric S-shaped body morphogenesis	4.906073e-3
GO:0051182	coenzyme transport	4.906073e-3
GO:0072278	metanephric comma-shaped body morphogenesis	4.906073e-3
GO:0072171	mesonephric tubule morphogenesis	5.127305e-3
GO:0023021	termination of signal transduction	5.201862e-3
GO:0071316	cellular response to nicotine	5.282113e-3
GO:0055062	phosphate ion homeostasis	5.542599e-3
GO:0006710	androgen catabolic process	5.605148e-3
GO:0043525	positive regulation of neuron apoptosis	5.736119e-3
GO:0045446	endothelial cell differentiation	6.094683e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	6.101408e-3
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	6.101408e-3
GO:0006685	sphingomyelin catabolic process	6.101408e-3
GO:0051014	actin filament severing	6.120679e-3
GO:0007067	mitosis	6.135956e-3
GO:0000082	G1/S transition of mitotic cell cycle	6.147207e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	6.196604e-3
GO:0030222	eosinophil differentiation	6.237451e-3
GO:0034776	response to histamine	6.237451e-3
GO:0031120	snRNA pseudouridine synthesis	6.237451e-3
GO:0010616	negative regulation of cardiac muscle adaptation	6.237451e-3
GO:0001579	medium-chain fatty acid transport	6.237451e-3
GO:0006285	base-excision repair, AP site formation	6.237451e-3
GO:0071985	multivesicular body sorting pathway	6.263224e-3
GO:0044342	type B pancreatic cell proliferation	6.263224e-3
GO:0046898	response to cycloheximide	6.332676e-3
GO:0021533	cell differentiation in hindbrain	6.626768e-3
GO:0060134	prepulse inhibition	6.680931e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	6.759378e-3
GO:0003407	neural retina development	6.791861e-3
GO:0072202	cell differentiation involved in metanephros development	6.858813e-3
GO:0051301	cell division	6.974587e-3
GO:0051497	negative regulation of stress fiber assembly	7.219748e-3
GO:0060350	endochondral bone morphogenesis	7.276496e-3
GO:0042267	natural killer cell mediated cytotoxicity	7.444995e-3
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	7.452561e-3
GO:0042733	embryonic digit morphogenesis	7.461598e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	7.553890e-3
GO:0001823	mesonephros development	7.603072e-3
GO:0032409	regulation of transporter activity	7.662658e-3
GO:0033631	cell-cell adhesion mediated by integrin	7.666303e-3
GO:0003158	endothelium development	7.692945e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	7.857156e-3
GO:0006680	glucosylceramide catabolic process	7.979074e-3
GO:0006401	RNA catabolic process	7.995867e-3
GO:0003214	cardiac left ventricle morphogenesis	8.046605e-3
GO:0007379	segment specification	8.046605e-3
GO:0031670	cellular response to nutrient	8.052131e-3
GO:0006446	regulation of translational initiation	8.285499e-3
GO:0060764	cell-cell signaling involved in mammary gland development	8.319639e-3
GO:0072560	type B pancreatic cell maturation	8.319639e-3
GO:0048167	regulation of synaptic plasticity	8.325629e-3
GO:0008347	glial cell migration	8.496924e-3
GO:0033627	cell adhesion mediated by integrin	8.555187e-3
GO:0060348	bone development	8.689587e-3
GO:0022898	regulation of transmembrane transporter activity	8.753118e-3
GO:0072074	kidney mesenchyme development	8.810416e-3
GO:0046591	embryonic leg joint morphogenesis	8.888108e-3
GO:0014745	negative regulation of muscle adaptation	8.888108e-3
GO:0031282	regulation of guanylate cyclase activity	8.888108e-3
GO:0021542	dentate gyrus development	8.915361e-3
GO:0048671	negative regulation of collateral sprouting	8.919337e-3
GO:0006927	transformed cell apoptosis	8.919337e-3
GO:0003015	heart process	8.981798e-3
GO:0072176	nephric duct development	9.012157e-3
GO:0090185	negative regulation of kidney development	9.229282e-3
GO:0042503	tyrosine phosphorylation of Stat3 protein	9.229282e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	9.229282e-3
GO:0006857	oligopeptide transport	9.236883e-3
GO:0003062	regulation of heart rate by chemical signal	9.236883e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	9.252990e-3
GO:0010390	histone monoubiquitination	9.320029e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	9.782637e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	9.782637e-3
GO:0032465	regulation of cytokinesis	9.978477e-3
GO:0007098	centrosome cycle	1.000627e-2
GO:0070512	positive regulation of histone H4-K20 methylation	1.012794e-2
GO:2000620	positive regulation of histone H4-K16 acetylation	1.012794e-2
GO:2000617	positive regulation of histone H3-K9 acetylation	1.012794e-2
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.012794e-2
GO:0031860	telomeric 3' overhang formation	1.012794e-2
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	1.012794e-2
GO:0009789	positive regulation of abscisic acid mediated signaling pathway	1.012794e-2
GO:0021587	cerebellum morphogenesis	1.023304e-2
GO:0071872	cellular response to epinephrine stimulus	1.024995e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.024995e-2
GO:0034641	cellular nitrogen compound metabolic process	1.025810e-2
GO:0048478	replication fork protection	1.028963e-2
GO:0070625	zymogen granule exocytosis	1.028963e-2
GO:0006682	galactosylceramide biosynthetic process	1.028963e-2
GO:0035611	protein branching point deglutamylation	1.028963e-2
GO:0031284	positive regulation of guanylate cyclase activity	1.028963e-2
GO:0010918	positive regulation of mitochondrial membrane potential	1.028963e-2
GO:0001914	regulation of T cell mediated cytotoxicity	1.030909e-2
GO:0060047	heart contraction	1.052940e-2
GO:0016073	snRNA metabolic process	1.053908e-2
GO:0009084	glutamine family amino acid biosynthetic process	1.057597e-2
GO:0043271	negative regulation of ion transport	1.058392e-2
GO:0001659	temperature homeostasis	1.074363e-2
GO:0045075	regulation of interleukin-12 biosynthetic process	1.080515e-2
GO:0032228	regulation of synaptic transmission, GABAergic	1.083405e-2
GO:0000281	cytokinesis after mitosis	1.094412e-2
GO:0035095	behavioral response to nicotine	1.101424e-2
GO:0032347	regulation of aldosterone biosynthetic process	1.101424e-2
GO:0034645	cellular macromolecule biosynthetic process	1.105471e-2
GO:0007212	dopamine receptor signaling pathway	1.110720e-2
GO:0030033	microvillus assembly	1.117071e-2
GO:0046115	guanosine catabolic process	1.126116e-2
GO:0042930	enterobactin transport	1.126116e-2
GO:0090340	positive regulation of secretion of lysosomal enzymes	1.126116e-2
GO:0034418	urate biosynthetic process	1.126116e-2
GO:0090187	positive regulation of pancreatic juice secretion	1.126116e-2
GO:0090108	positive regulation of high-density lipoprotein particle assembly	1.126116e-2
GO:0007113	endomitotic cell cycle	1.126116e-2
GO:0006148	inosine catabolic process	1.126116e-2
GO:0006149	deoxyinosine catabolic process	1.126116e-2
GO:0006161	deoxyguanosine catabolic process	1.126116e-2
GO:0009249	protein lipoylation	1.126116e-2
GO:0031118	rRNA pseudouridine synthesis	1.126116e-2
GO:0032467	positive regulation of cytokinesis	1.131254e-2
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.140727e-2
GO:0090086	negative regulation of protein deubiquitination	1.140727e-2
GO:0021761	limbic system development	1.144452e-2
GO:0002676	regulation of chronic inflammatory response	1.146219e-2
GO:0021527	spinal cord association neuron differentiation	1.175720e-2
GO:0071901	negative regulation of protein serine/threonine kinase activity	1.199268e-2
GO:0021678	third ventricle development	1.225391e-2
GO:0072180	mesonephric duct morphogenesis	1.225391e-2
GO:0014826	vein smooth muscle contraction	1.225391e-2
GO:0010332	response to gamma radiation	1.251037e-2
GO:0032259	methylation	1.263813e-2
GO:0030219	megakaryocyte differentiation	1.267864e-2
GO:0033555	multicellular organismal response to stress	1.269426e-2
GO:0060743	epithelial cell maturation involved in prostate gland development	1.293506e-2
GO:0061290	canonical Wnt receptor signaling pathway involved in metanephric kidney development	1.293506e-2
GO:0030433	ER-associated protein catabolic process	1.316544e-2
GO:0048285	organelle fission	1.323204e-2
GO:0042596	fear response	1.334364e-2
GO:0048496	maintenance of organ identity	1.340205e-2
GO:0051970	negative regulation of transmission of nerve impulse	1.354870e-2
GO:0032006	regulation of TOR signaling cascade	1.365074e-2
GO:0048639	positive regulation of developmental growth	1.373354e-2
GO:0060319	primitive erythrocyte differentiation	1.424011e-2
GO:0046479	glycosphingolipid catabolic process	1.424011e-2
GO:0045292	nuclear mRNA cis splicing, via spliceosome	1.424011e-2
GO:0001839	neural plate morphogenesis	1.430607e-2
GO:0032970	regulation of actin filament-based process	1.431246e-2
GO:0032908	regulation of transforming growth factor beta1 production	1.443125e-2
GO:0006366	transcription from RNA polymerase II promoter	1.454949e-2
GO:0031396	regulation of protein ubiquitination	1.456829e-2
GO:0071635	negative regulation of transforming growth factor beta production	1.461821e-2
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	1.485905e-2
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.485905e-2
GO:2001076	positive regulation of metanephric ureteric bud development	1.485905e-2
GO:0044268	multicellular organismal protein metabolic process	1.485905e-2
GO:0010960	magnesium ion homeostasis	1.485905e-2
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	1.485905e-2
GO:0007356	thorax and anterior abdomen determination	1.485905e-2
GO:0006189	'de novo' IMP biosynthetic process	1.485905e-2
GO:0072210	metanephric nephron development	1.496638e-2
GO:0048813	dendrite morphogenesis	1.506605e-2
GO:0014043	negative regulation of neuron maturation	1.518593e-2
GO:0070925	organelle assembly	1.522830e-2
GO:0045988	negative regulation of striated muscle contraction	1.524914e-2
GO:0033205	cell cycle cytokinesis	1.528774e-2
GO:0021846	cell proliferation in forebrain	1.555623e-2
GO:0046519	sphingoid metabolic process	1.556077e-2
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	1.572303e-2
GO:0045023	G0 to G1 transition	1.572303e-2
GO:2000001	regulation of DNA damage checkpoint	1.572303e-2
GO:0008355	olfactory learning	1.572303e-2
GO:0019402	galactitol metabolic process	1.572303e-2
GO:0048260	positive regulation of receptor-mediated endocytosis	1.573948e-2
GO:0015809	arginine transport	1.576878e-2
GO:0097012	response to granulocyte macrophage colony-stimulating factor stimulus	1.594693e-2
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.594693e-2
GO:0043401	steroid hormone mediated signaling pathway	1.605129e-2
GO:0045901	positive regulation of translational elongation	1.614015e-2
GO:0045905	positive regulation of translational termination	1.614015e-2
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.614015e-2
GO:0006452	translational frameshifting	1.614015e-2
GO:0072498	embryonic skeletal joint development	1.615678e-2
GO:0090007	regulation of mitotic anaphase	1.621094e-2
GO:0090399	replicative senescence	1.628157e-2
GO:0018342	protein prenylation	1.635567e-2
GO:0046070	dGTP metabolic process	1.635567e-2
GO:0072190	ureter urothelium development	1.645950e-2
GO:0060556	regulation of vitamin D biosynthetic process	1.645950e-2
GO:0021592	fourth ventricle development	1.645950e-2
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.652615e-2
GO:0070830	tight junction assembly	1.674136e-2
GO:0032753	positive regulation of interleukin-4 production	1.674136e-2
GO:0015074	DNA integration	1.674136e-2
GO:0001958	endochondral ossification	1.702523e-2
GO:0006904	vesicle docking involved in exocytosis	1.715593e-2
GO:0006672	ceramide metabolic process	1.728621e-2
GO:0022402	cell cycle process	1.763328e-2
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	1.771543e-2
GO:0017144	drug metabolic process	1.773935e-2
GO:0002315	marginal zone B cell differentiation	1.784784e-2
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.811654e-2
GO:0000910	cytokinesis	1.822171e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.830071e-2
GO:0016574	histone ubiquitination	1.833085e-2
GO:0034205	beta-amyloid formation	1.866275e-2
GO:0032065	cortical protein anchoring	1.866275e-2
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.866275e-2
GO:0010701	positive regulation of norepinephrine secretion	1.866275e-2
GO:0061387	regulation of extent of cell growth	1.875133e-2
GO:0060259	regulation of feeding behavior	1.882839e-2
GO:0046339	diacylglycerol metabolic process	1.882839e-2
GO:0040016	embryonic cleavage	1.882850e-2
GO:0045835	negative regulation of meiosis	1.892738e-2
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	1.897316e-2
GO:0046881	positive regulation of follicle-stimulating hormone secretion	1.897316e-2
GO:0019532	oxalate transport	1.897316e-2
GO:0015802	basic amino acid transport	1.930770e-2
GO:0006261	DNA-dependent DNA replication	1.937183e-2
GO:0072268	pattern specification involved in metanephros development	1.963087e-2
GO:0032916	positive regulation of transforming growth factor beta3 production	1.963087e-2
GO:0042036	negative regulation of cytokine biosynthetic process	1.971854e-2
GO:0018126	protein hydroxylation	1.983972e-2
GO:0060235	lens induction in camera-type eye	1.985349e-2
GO:0070373	negative regulation of ERK1 and ERK2 cascade	1.991155e-2
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	2.012717e-2
GO:0030522	intracellular receptor mediated signaling pathway	2.018564e-2
GO:0019067	viral assembly, maturation, egress, and release	2.028855e-2
GO:0051438	regulation of ubiquitin-protein ligase activity	2.030191e-2
GO:0006415	translational termination	2.054191e-2
GO:0006463	steroid hormone receptor complex assembly	2.054191e-2
GO:0071636	positive regulation of transforming growth factor beta production	2.060018e-2
GO:0009059	macromolecule biosynthetic process	2.064558e-2
GO:0032956	regulation of actin cytoskeleton organization	2.081254e-2
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2.099292e-2
GO:0006184	GTP catabolic process	2.103943e-2
GO:0009755	hormone-mediated signaling pathway	2.111420e-2