CL:0000557: Difference between revisions
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|name=granulocyte monocyte progenitor cell | |name=granulocyte monocyte progenitor cell | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0002371 | |part_of=UBERON:0002371 | ||
Latest revision as of 16:34, 12 September 2014
| Name: | granulocyte monocyte progenitor cell |
|---|---|
| Namespace: | FANTOM |
| Definition: | "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata-1, Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251] |
| Synonyms: |
"CFU-C , Colony forming unit in culture" BROAD [1] "CFU-GM" EXACT [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] "colony forming unit granulocyte macrophage" EXACT [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] "GMP" EXACT [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] "granulocyte-macrophage progenitor" EXACT [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] |
| Comments: | Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID: 19243617). GMPs are reportedly CD34-positive, CD38-positive, CD45RA-positive, and CD123-positive. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000763(myeloid cell),CL:0001012(CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor),CL:1001610(bone marrow hematopoietic cell) |
|---|---|
| develops_from: | CL:0000049(common myeloid progenitor) |
| part_of: | UBERON:0002371(bone marrow) |
Children
| disjoint from: | CL:0000049 (common myeloid progenitor),CL:0000050 (megakaryocyte-erythroid progenitor cell) |
|---|---|
| derives from: | FF:0000070 (granulocyte macrophage progenitor cell sample) |
| develops from: | CL:0000835 (myeloblast),CL:0002009 (macrophage dendritic cell progenitor),CL:0002028 (basophil mast progenitor cell) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 12123-128C8 (granulocyte macrophage progenitor GMP, biol_rep1)
- 12126-128D2 (granulocyte macrophage progenitor GMP, biol_rep2)
- 12129-128D5 (granulocyte macrophage progenitor GMP, biol_rep3)
- 12131-128D7 (granulocyte macrophage progenitor, donor1)
- 12135-128E2 (granulocyte macrophage progenitor, donor2)
- 12139-128E6 (granulocyte macrophage progenitor, donor3)
Mouse (Mus musculus)
- 12123-128C8 (granulocyte macrophage progenitor GMP, biol_rep1)
- 12126-128D2 (granulocyte macrophage progenitor GMP, biol_rep2)
- 12129-128D5 (granulocyte macrophage progenitor GMP, biol_rep3)
- 12131-128D7 (granulocyte macrophage progenitor, donor1)
- 12135-128E2 (granulocyte macrophage progenitor, donor2)
- 12139-128E6 (granulocyte macrophage progenitor, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000557 (granulocyte monocyte progenitor cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.22e-136 | FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_a11ccc43e34d0b48429aa8ea50fb7bd1 | p@chr1:161187824..161187847, + |
| 1.22e-136 | FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_a11ccc43e34d0b48429aa8ea50fb7bd1 | p@chr1:161187824..161187847, + |
| 6.46e-132 | FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_24bf4e1d003a175beb60951b15c26690 | p@chr16:50313426..50313459, + |
| 6.46e-132 | FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_24bf4e1d003a175beb60951b15c26690 | p@chr16:50313426..50313459, + |
| 1.98e-131 | FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_0cd7adf95883f31a4e11aec714e9d502 | p@chr1:161188661..161188679, + |
| 1.98e-131 | FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_0cd7adf95883f31a4e11aec714e9d502 | p@chr1:161188661..161188679, + |
| 6.11e-130 | FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_edf397f59b453398022e9f69333c6441 | p7@EMILIN2 |
| 6.11e-130 | FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_edf397f59b453398022e9f69333c6441 | p7@EMILIN2 |
| 4.57e-129 | FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_d2dc56dcc174792eac79892dfc152325 | p@chr7:77050554..77050601, + |
| 4.57e-129 | FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_d2dc56dcc174792eac79892dfc152325 | p@chr7:77050554..77050601, + |
| 9.16e-128 | FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_a5086834f8a8e902bfc00c1ea6446a93 | p@chr1:161188746..161188758, + |
| 9.16e-128 | FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_a5086834f8a8e902bfc00c1ea6446a93 | p@chr1:161188746..161188758, + |
| 8.22e-127 | FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_cf49226623cce6110a28f7f564fd9d4b | p@chr17:7482481..7482508, - |
| 8.22e-127 | FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_cf49226623cce6110a28f7f564fd9d4b | p@chr17:7482481..7482508, - |
| 1.66e-126 | FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_9fe797cdfa67f5df82073d304674d271 | p5@IFI30 |
| 1.66e-126 | FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_9fe797cdfa67f5df82073d304674d271 | p5@IFI30 |
| 1.87e-125 | FFCP PHASE1:Hg19::chr4:3387239..3387324,-#_9ca27ea82a3341168c7b27a765c662a2 | p@chr4:3387239..3387324, - |
| 1.87e-125 | FFCP PHASE2:Hg19::chr4:3387239..3387324,-#_9ca27ea82a3341168c7b27a765c662a2 | p@chr4:3387239..3387324, - |
| 1.83e-123 | FFCP PHASE2:Hg19::chr7:2832730..2832791,+#_214513c8cc313667afb0e2059bbc7d77 | p@chr7:2832730..2832791, + |
| 1.83e-123 | FFCP PHASE1:Hg19::chr7:2832730..2832791,+#_214513c8cc313667afb0e2059bbc7d77 | p@chr7:2832730..2832791, + |
| 2.42e-122 | FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_3d6795bff4765484f0d06fb37b4bec5e | p15@MGAT1 |
| 2.42e-122 | FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_3d6795bff4765484f0d06fb37b4bec5e | p15@MGAT1 |
| 4.19e-122 | FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_9be0fa50ddec0d252e25307b3c21ecf1 | p7@IFI30 |
| 4.19e-122 | FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_9be0fa50ddec0d252e25307b3c21ecf1 | p7@IFI30 |
| 1.2e-121 | FFCP PHASE2:Hg19::chr1:111743000..111743011,+#_78d1a4bd88b85f42876d3c7385eb1407 | p8@CHI3L2 |
| 1.2e-121 | FFCP PHASE1:Hg19::chr1:111743000..111743011,+#_78d1a4bd88b85f42876d3c7385eb1407 | p8@CHI3L2 |
| 3.34e-121 | FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_24dd7c92172312785d7b9a859b0af497 | p1@AK126179 |
| 3.34e-121 | FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_24dd7c92172312785d7b9a859b0af497 | p1@AK126179 |
| 3.43e-120 | FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_fea4df9e87cfff344f1b16237862724c | p@chr19:18286116..18286156, + |
| 3.43e-120 | FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_fea4df9e87cfff344f1b16237862724c | p@chr19:18286116..18286156, + |
| 1.26e-119 | FFCP PHASE2:Hg19::chr17:72542163..72542182,-#_f5182f03712a03bd92c23e7d9d9b5d91 | p2@CD300C |
| 1.26e-119 | FFCP PHASE1:Hg19::chr17:72542163..72542182,-#_f5182f03712a03bd92c23e7d9d9b5d91 | p2@CD300C |
| 1.37e-118 | FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_39b203bbe6a3dd0c86757cfd75a3ab7c | p1@CYP1B1-AS1 |
| 1.37e-118 | FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_39b203bbe6a3dd0c86757cfd75a3ab7c | p1@CYP1B1-AS1 |
| 1.51e-118 | FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_17f36752570be8be38771f7a9aac0cc3 | p@chr15:65174546..65174583, - |
| 1.51e-118 | FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_17f36752570be8be38771f7a9aac0cc3 | p@chr15:65174546..65174583, - |
| 3.4e-118 | FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_5a5aebb1de2cd58d6057663e0a14dada | p7@FNIP2 |
| 3.4e-118 | FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_5a5aebb1de2cd58d6057663e0a14dada | p7@FNIP2 |
| 1.14e-117 | FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_fc42dc1f210fe44375815a72b1301e36 | p@chr4:185314125..185314143, - |
| 1.14e-117 | FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_fc42dc1f210fe44375815a72b1301e36 | p@chr4:185314125..185314143, - |
| 4.04e-117 | FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_44d68d7e0ab0d15e307f056bcec34baf | p7@RNF13 |
| 4.04e-117 | FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_44d68d7e0ab0d15e307f056bcec34baf | p7@RNF13 |
| 7.68e-117 | FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_12fb7373cd683929d62fe8f184860ef9 | p@chr1:161188686..161188721, + |
| 7.68e-117 | FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_12fb7373cd683929d62fe8f184860ef9 | p@chr1:161188686..161188721, + |
| 1.34e-116 | FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_5b3fbdb5f0242d8b7929a4cb26d41b11 | p@chr2:119726719..119726744, + |
| 1.34e-116 | FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_5b3fbdb5f0242d8b7929a4cb26d41b11 | p@chr2:119726719..119726744, + |
| 1.55e-116 | FFCP PHASE1:Hg19::chr19:52299474..52299504,-#_ad75fad916de90af2d89686b92630a32 | p@chr19:52299474..52299504, - |
| 1.55e-116 | FFCP PHASE2:Hg19::chr19:52299474..52299504,-#_ad75fad916de90af2d89686b92630a32 | p@chr19:52299474..52299504, - |
| 5.12e-116 | FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_72e5cc66b7417f91917ea204887d60f5 | p1@ENST00000425320 |
| 5.12e-116 | FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_72e5cc66b7417f91917ea204887d60f5 | p1@ENST00000425320 |
| 9.64e-116 | FFCP PHASE1:Hg19::chr10:73648356..73648408,-#_0ce618f8285f33af865d16ed310d79ed | p@chr10:73648356..73648408, - |
| 9.64e-116 | FFCP PHASE2:Hg19::chr10:73648356..73648408,-#_0ce618f8285f33af865d16ed310d79ed | p@chr10:73648356..73648408, - |
| 9.84e-116 | FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_94c6f6a7d52c066869db179f7a78538c | p@chr4:185314151..185314178, - |
| 9.84e-116 | FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_94c6f6a7d52c066869db179f7a78538c | p@chr4:185314151..185314178, - |
| 1.24e-115 | FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_99ff12aa13396b3d8b19283b2734df50 | p@chr2:145429606..145429658, + |
| 1.24e-115 | FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_99ff12aa13396b3d8b19283b2734df50 | p@chr2:145429606..145429658, + |
| 3.24e-115 | FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_2456ed7b3af590b72e7384db85e26732 | p@chr19:18288064..18288080, + |
| 3.24e-115 | FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_2456ed7b3af590b72e7384db85e26732 | p@chr19:18288064..18288080, + |
| 4.02e-115 | FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_6f07e392e342ff5ab8a2ffea4b586f41 | p@chrX:153286067..153286101, - |
| 4.02e-115 | FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_6f07e392e342ff5ab8a2ffea4b586f41 | p@chrX:153286067..153286101, - |
| 1.44e-114 | FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_46014b0d1434df2a679006680ca89561 | p@chr4:185314188..185314207, - |
| 1.44e-114 | FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_46014b0d1434df2a679006680ca89561 | p@chr4:185314188..185314207, - |
| 1.54e-114 | FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_bd9877b2f7ff42599e300623f50e74c2 | p@chrX:37664331..37664352, + |
| 1.54e-114 | FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_bd9877b2f7ff42599e300623f50e74c2 | p@chrX:37664331..37664352, + |
| 1.59e-114 | FFCP PHASE2:Hg19::chr1:161188826..161188842,+#_ba6090bb00a3c8d1e36e4c4616645866 | p@chr1:161188826..161188842, + |
| 1.59e-114 | FFCP PHASE1:Hg19::chr1:161188826..161188842,+#_ba6090bb00a3c8d1e36e4c4616645866 | p@chr1:161188826..161188842, + |
| 1.87e-114 | FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_2e8feb13f2bfbe65ed2dcb5b11cec14c | p8@CTSS |
| 1.87e-114 | FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_2e8feb13f2bfbe65ed2dcb5b11cec14c | p8@CTSS |
| 5.37e-114 | FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_d5526812523aeb2ba54037baf3542b11 | p2@ZEB2-AS1 |
| 5.37e-114 | FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_d5526812523aeb2ba54037baf3542b11 | p2@ZEB2-AS1 |
| 6.51e-114 | FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_449b747ceba67a5a019fcb5409c2d137 | p@chr19:18285955..18285972, + |
| 6.51e-114 | FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_449b747ceba67a5a019fcb5409c2d137 | p@chr19:18285955..18285972, + |
| 9.3e-114 | FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_c6d2ce9ebfe03a69507efaf4d0a39dfe | p@chr8:116588888..116588904, + |
| 9.3e-114 | FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_c6d2ce9ebfe03a69507efaf4d0a39dfe | p@chr8:116588888..116588904, + |
| 1.42e-113 | FFCP PHASE2:Hg19::chr1:145610717..145610730,+#_dc4b750e1157c55dde9fc37a7f56c0dc | p4@RNF115 |
| 1.42e-113 | FFCP PHASE1:Hg19::chr1:145610717..145610730,+#_dc4b750e1157c55dde9fc37a7f56c0dc | p4@RNF115 |
| 4.0e-113 | FFCP PHASE2:Hg19::chr2:129283966..129283970,+#_d68a54eefcea00359ff54066b91d349e | p@chr2:129283966..129283970, + |
| 4.0e-113 | FFCP PHASE1:Hg19::chr2:129283966..129283970,+#_d68a54eefcea00359ff54066b91d349e | p@chr2:129283966..129283970, + |
| 5.85e-113 | FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_2ba044c8a0ff09d83891675c88fff299 | p@chr19:18283959..18283993, + |
| 5.85e-113 | FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_2ba044c8a0ff09d83891675c88fff299 | p@chr19:18283959..18283993, + |
| 8.33e-113 | FFCP PHASE2:Hg19::chr20:1517991..1518011,-#_bd89701fa99853b2ceda033fe7f59b58 | p@chr20:1517991..1518011, - |
| 8.33e-113 | FFCP PHASE1:Hg19::chr20:1517991..1518011,-#_bd89701fa99853b2ceda033fe7f59b58 | p@chr20:1517991..1518011, - |
| 1.49e-112 | FFCP PHASE1:Hg19::chr1:108593061..108593077,+#_c8b467d9bfef56c6da822775376fc5d8 | p@chr1:108593061..108593077, + |
| 1.49e-112 | FFCP PHASE2:Hg19::chr1:108593061..108593077,+#_c8b467d9bfef56c6da822775376fc5d8 | p@chr1:108593061..108593077, + |
| 1.89e-112 | FFCP PHASE1:Hg19::chr19:18288914..18288931,-#_5990873cee06711a2f86ba43a7ed2600 | p5@CU676849, p5@CU689079 |
| 1.89e-112 | FFCP PHASE2:Hg19::chr19:18288914..18288931,-#_5990873cee06711a2f86ba43a7ed2600 | p5@CU676849, p5@CU689079 |
| 4.76e-112 | FFCP PHASE1:Hg19::chr19:18288514..18288554,+#_57b23fa5e5585f31033b216f03b2dd5f | p6@IFI30 |
| 4.76e-112 | FFCP PHASE2:Hg19::chr19:18288514..18288554,+#_57b23fa5e5585f31033b216f03b2dd5f | p6@IFI30 |
| 6.25e-112 | FFCP PHASE1:Hg19::chr5:180242576..180242585,-#_e45d6f3c004c29ad8cce7f6a1cca3b18 | p12@MGAT1 |
| 6.25e-112 | FFCP PHASE2:Hg19::chr5:180242576..180242585,-#_e45d6f3c004c29ad8cce7f6a1cca3b18 | p12@MGAT1 |
| 1.15e-111 | FFCP PHASE2:Hg19::chr7:128503395..128503414,+#_ccea79432ea4f3dc33d5b43cc8fc97e1 | p@chr7:128503395..128503414, + |
| 1.15e-111 | FFCP PHASE1:Hg19::chr7:128503395..128503414,+#_ccea79432ea4f3dc33d5b43cc8fc97e1 | p@chr7:128503395..128503414, + |
| 1.58e-111 | FFCP PHASE2:Hg19::chr8:53373491..53373506,-#_ece0ae84f57e0121b4d417edadc07225 | p4@ST18 |
| 1.58e-111 | FFCP PHASE1:Hg19::chr8:53373491..53373506,-#_ece0ae84f57e0121b4d417edadc07225 | p4@ST18 |
| 3.68e-111 | FFCP PHASE1:Hg19::chr7:6066589..6066602,-#_74aae7e7528f0b4a87d6f02920a6cd60 | p4@EIF2AK1 |
| 3.68e-111 | FFCP PHASE2:Hg19::chr7:6066589..6066602,-#_74aae7e7528f0b4a87d6f02920a6cd60 | p4@EIF2AK1 |
| 3.91e-111 | FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_649c3d37e3e9f1a2879eb418b36ea4d7 | p@chr17:7483714..7483726, + |
| 3.91e-111 | FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_649c3d37e3e9f1a2879eb418b36ea4d7 | p@chr17:7483714..7483726, + |
| 1.05e-110 | FFCP PHASE1:Hg19::chr1:161187774..161187799,+#_60d9eafbb55b8e6fefad623b5cbb80f9 | p@chr1:161187774..161187799, + |
| 1.05e-110 | FFCP PHASE2:Hg19::chr1:161187774..161187799,+#_60d9eafbb55b8e6fefad623b5cbb80f9 | p@chr1:161187774..161187799, + |
