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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C193_Mesenchymal_Adipocyte_mature_Cardiac_heart_CD14CD16_CD14
|full_id=C193_Mesenchymal_Adipocyte_mature_Cardiac_heart_CD14CD16_CD14
|gostat_on_coexpression_clusters=GO:0048518!positive regulation of biological process!0.00140632531219541!1675;2323;10922;63924;348;5524;1029;10174$GO:0048522!positive regulation of cellular process!0.00388887713003141!348;5524;10174;1029;2323;10922;63924$GO:0006917!induction of apoptosis!0.00392172611206062!348;1029;10922;63924$GO:0012502!induction of programmed cell death!0.00392172611206062!348;1029;10922;63924$GO:0005625!soluble fraction!0.00392172611206062!833;5524;2192;2323$GO:0045936!negative regulation of phosphate metabolic process!0.00392172611206062!5524;1029$GO:0043065!positive regulation of apoptosis!0.00392172611206062!348;1029;10922;63924$GO:0043068!positive regulation of programmed cell death!0.00392172611206062!348;1029;10922;63924$GO:0042632!cholesterol homeostasis!0.00392172611206062!3949;348$GO:0055092!sterol homeostasis!0.00392172611206062!3949;348$GO:0055088!lipid homeostasis!0.00438854313126638!3949;348$GO:0015918!sterol transport!0.00438854313126638!3949;348$GO:0030301!cholesterol transport!0.00438854313126638!3949;348$GO:0008034!lipoprotein binding!0.0107484795777597!3949;348$GO:0065007!biological regulation!0.0178024265771723!6237;1675;55663;2323;140467;10922;63924;3949;348;55806;5524;10174;56731;1029$GO:0050789!regulation of biological process!0.0191590005068112!6237;1675;55663;2323;140467;10922;63924;348;55806;5524;10174;56731;1029$GO:0003817!complement factor D activity!0.0191590005068112!1675$GO:0050749!apolipoprotein E receptor binding!0.0191590005068112!348$GO:0032515!negative regulation of phosphoprotein phosphatase activity!0.0191590005068112!5524$GO:0030229!very-low-density lipoprotein receptor activity!0.0191590005068112!3949$GO:0032516!positive regulation of phosphoprotein phosphatase activity!0.0191590005068112!5524$GO:0035305!negative regulation of dephosphorylation!0.0191590005068112!5524$GO:0035308!negative regulation of protein amino acid dephosphorylation!0.0191590005068112!5524$GO:0042981!regulation of apoptosis!0.0259099367043505!348;1029;10922;63924$GO:0043067!regulation of programmed cell death!0.0259099367043505!348;1029;10922;63924$GO:0050794!regulation of cellular process!0.0259099367043505!6237;55663;2323;140467;10922;63924;348;55806;5524;10174;1029;56731$GO:0051174!regulation of phosphorus metabolic process!0.0259099367043505!5524;1029$GO:0019220!regulation of phosphate metabolic process!0.0259099367043505!5524;1029$GO:0008160!protein tyrosine phosphatase activator activity!0.0259099367043505!5524$GO:0048156!tau protein binding!0.0259099367043505!348$GO:0035306!positive regulation of dephosphorylation!0.0259099367043505!5524$GO:0035304!regulation of protein amino acid dephosphorylation!0.0259099367043505!5524$GO:0035307!positive regulation of protein amino acid dephosphorylation!0.0259099367043505!5524$GO:0010149!senescence!0.0259099367043505!1029$GO:0008203!cholesterol metabolic process!0.030957613977377!3949;348$GO:0042157!lipoprotein metabolic process!0.0319799892743909!3949;348$GO:0051496!positive regulation of stress fiber formation!0.0319799892743909!10174$GO:0051004!regulation of lipoprotein lipase activity!0.0319799892743909!5524$GO:0051495!positive regulation of cytoskeleton organization and biogenesis!0.0319799892743909!10174$GO:0032233!positive regulation of actin filament bundle formation!0.0319799892743909!10174$GO:0031232!extrinsic to external side of plasma membrane!0.0319799892743909!348$GO:0043086!negative regulation of catalytic activity!0.0319799892743909!5524;1029$GO:0016125!sterol metabolic process!0.0363570142838911!3949;348$GO:0005319!lipid transporter activity!0.0370265024419312!3949;348$GO:0051721!protein phosphatase 2A binding!0.0374547283925113!5524$GO:0045192!low-density lipoprotein catabolic process!0.0374547283925113!3949$GO:0032088!inhibition of NF-kappaB transcription factor!0.0374547283925113!1029$GO:0031589!cell-substrate adhesion!0.0389496332072172!10174;1029$GO:0035303!regulation of dephosphorylation!0.0439905280809569!5524$GO:0017166!vinculin binding!0.0439905280809569!10174$GO:0031324!negative regulation of cellular metabolic process!0.0444126921707153!5524;10174;1029$GO:0051346!negative regulation of hydrolase activity!0.0454880282252511!5524$GO:0006423!cysteinyl-tRNA aminoacylation!0.0454880282252511!833$GO:0004817!cysteine-tRNA ligase activity!0.0454880282252511!833$GO:0033344!cholesterol efflux!0.0454880282252511!348$GO:0042159!lipoprotein catabolic process!0.0454880282252511!3949$GO:0051492!regulation of stress fiber formation!0.0454880282252511!10174$GO:0032231!regulation of actin filament bundle formation!0.0454880282252511!10174$GO:0043038!amino acid activation!0.0456459809016163!833;7407$GO:0006418!tRNA aminoacylation for protein translation!0.0456459809016163!833;7407$GO:0043039!tRNA aminoacylation!0.0456459809016163!833;7407$GO:0001953!negative regulation of cell-matrix adhesion!0.0456459809016163!1029$GO:0043149!stress fiber formation!0.0456459809016163!10174$GO:0006869!lipid transport!0.0456459809016163!3949;348$GO:0016876!ligase activity, forming aminoacyl-tRNA and related compounds!0.0456459809016163!833;7407$GO:0016875!ligase activity, forming carbon-oxygen bonds!0.0456459809016163!833;7407$GO:0004812!aminoacyl-tRNA ligase activity!0.0456459809016163!833;7407$GO:0006915!apoptosis!0.0456459809016163!348;1029;10922;63924$GO:0009892!negative regulation of metabolic process!0.0456459809016163!5524;10174;1029$GO:0012501!programmed cell death!0.0456459809016163!348;1029;10922;63924$GO:0030299!cholesterol absorption!0.0456459809016163!3949$GO:0043410!positive regulation of MAPKKK cascade!0.0456459809016163!10174$GO:0000045!autophagic vacuole formation!0.0456459809016163!285973$GO:0042627!chylomicron!0.0456459809016163!348$GO:0044241!lipid digestion!0.0456459809016163!3949$GO:0050750!low-density lipoprotein receptor binding!0.0456459809016163!348$GO:0045471!response to ethanol!0.0456459809016163!348$GO:0000267!cell fraction!0.0469230363482118!833;5524;2192;2323$GO:0045736!negative regulation of cyclin-dependent protein kinase activity!0.0469230363482118!1029$GO:0016236!macroautophagy!0.0469230363482118!285973$GO:0006707!cholesterol catabolic process!0.0469230363482118!348$GO:0016127!sterol catabolic process!0.0469230363482118!348$GO:0048168!regulation of neuronal synaptic plasticity!0.0469230363482118!348$GO:0016265!death!0.0469230363482118!348;1029;10922;63924$GO:0008219!cell death!0.0469230363482118!348;1029;10922;63924$GO:0050892!intestinal absorption!0.0498827202411778!3949$GO:0001540!beta-amyloid binding!0.0498827202411778!348$GO:0022408!negative regulation of cell-cell adhesion!0.0498827202411778!1029
|id=C193
|id=C193
}}
}}

Revision as of 17:36, 18 May 2012


Full id: C193_Mesenchymal_Adipocyte_mature_Cardiac_heart_CD14CD16_CD14



Phase1 CAGE Peaks

Hg19::chr10:105211353..105211386,-p4@CALHM2
Hg19::chr10:73047521..73047525,+p@chr10:73047521..73047525
+
Hg19::chr10:99123608..99123611,-p4@RRP12
Hg19::chr11:113930128..113930159,-p@chr11:113930128..113930159
-
Hg19::chr11:114050496..114050536,+p@chr11:114050496..114050536
+
Hg19::chr11:3078838..3078876,-p6@CARS
Hg19::chr11:67134927..67134931,-p@chr11:67134927..67134931
-
Hg19::chr11:7687678..7687681,-p@chr11:7687678..7687681
-
Hg19::chr11:9781782..9781788,-p@chr11:9781782..9781788
-
Hg19::chr12:53455252..53455256,+p9@TENC1
Hg19::chr14:105818803..105818808,+p@chr14:105818803..105818808
+
Hg19::chr15:35731807..35731812,+p@chr15:35731807..35731812
+
Hg19::chr15:64448917..64448928,-p@chr15:64448917..64448928
-
Hg19::chr15:90328175..90328186,-p@chr15:90328175..90328186
-
Hg19::chr15:90344339..90344342,-p@chr15:90344339..90344342
-
Hg19::chr16:2819861..2819890,+p@chr16:2819861..2819890
+
Hg19::chr16:30662360..30662387,+p7@PRR14
Hg19::chr16:67701309..67701312,-p@chr16:67701309..67701312
-
Hg19::chr16:86797626..86797635,-p@chr16:86797626..86797635
-
Hg19::chr16:89595986..89595990,+p@chr16:89595986..89595990
+
Hg19::chr16:89628797..89628803,+p3@RPL13
Hg19::chr17:27894290..27894311,+p@chr17:27894290..27894311
+
Hg19::chr17:36862346..36862379,-p@chr17:36862346..36862379
-
Hg19::chr17:43013396..43013400,-p2@KIF18B
Hg19::chr17:61571793..61571795,+p@chr17:61571793..61571795
+
Hg19::chr17:79204340..79204344,-p@chr17:79204340..79204344
-
Hg19::chr19:11217362..11217367,+p6@LDLR
Hg19::chr19:17378331..17378339,+p3@BABAM1
Hg19::chr19:3620703..3620705,-p2@C19orf29
Hg19::chr19:36239576..36239581,+p6@LIN37
Hg19::chr19:45409274..45409280,+p6@APOE
Hg19::chr19:46894342..46894354,+p@chr19:46894342..46894354
+
Hg19::chr19:47778119..47778195,+p1@PRR24
Hg19::chr19:49977466..49977514,+p2@FLT3LG
Hg19::chr19:50143452..50143468,-p2@RRAS
Hg19::chr19:52097813..52097865,+p@chr19:52097813..52097865
+
Hg19::chr19:55758241..55758245,-p11@PPP6R1
Hg19::chr19:58987786..58987805,+p3@ZNF446
Hg19::chr19:7584815..7584829,+p2@ZNF358
Hg19::chr19:850817..850829,+p@chr19:850817..850829
+
Hg19::chr19:850985..851002,+p@chr19:850985..851002
+
Hg19::chr19:8590447..8590459,-p@chr19:8590447..8590459
-
Hg19::chr19:859425..859481,+p2@CFD
Hg19::chr19:859654..859672,+p1@CFD
Hg19::chr1:145556687..145556690,+p@chr1:145556687..145556690
+
Hg19::chr1:27269555..27269558,+p@chr1:27269555..27269558
+
Hg19::chr1:33834133..33834136,-p@chr1:33834133..33834136
-
Hg19::chr20:62293295..62293299,+p@chr20:62293295..62293299
+
Hg19::chr20:62371206..62371224,+p6@SLC2A4RG
Hg19::chr21:46386905..46386944,+p@chr21:46386905..46386944
+
Hg19::chr21:47423384..47423395,+p@chr21:47423384..47423395
+
Hg19::chr21:47680704..47680707,-p@chr21:47680704..47680707
-
Hg19::chr22:24577444..24577465,+p1@SUSD2
Hg19::chr22:24581731..24581748,+p@chr22:24581731..24581748
+
Hg19::chr22:24584625..24584636,+p@chr22:24584625..24584636
+
Hg19::chr22:45898503..45898514,+p11@FBLN1
Hg19::chr22:45898527..45898538,+p7@FBLN1
Hg19::chr22:46493889..46493892,+p@chr22:46493889..46493892
+
Hg19::chr3:10359730..10359734,-p4@SEC13
Hg19::chr3:45067642..45067645,+p7@CLEC3B
Hg19::chr3:52029054..52029058,-p@chr3:52029054..52029058
-
Hg19::chr3:9920487..9920502,-p2@CIDEC
Hg19::chr3:9920507..9920519,-p4@CIDEC
Hg19::chr3:9920535..9920548,-p3@CIDEC
Hg19::chr3:9956869..9956894,+p@chr3:9956869..9956894
+
Hg19::chr3:9956901..9956922,+p@chr3:9956901..9956922
+
Hg19::chr3:9956948..9956961,+p@chr3:9956948..9956961
+
Hg19::chr3:9958774..9958848,+p1@IL17RC
Hg19::chr3:9958849..9958863,+p2@IL17RC
Hg19::chr3:9958870..9958879,+p3@IL17RC
Hg19::chr4:5798958..5798961,+p@chr4:5798958..5798961
+
Hg19::chr4:891819..891820,-p@chr4:891819..891820
-
Hg19::chr5:149425247..149425250,+p@chr5:149425247..149425250
+
Hg19::chr6:31763316..31763327,-p7@VARS
Hg19::chr7:100201583..100201598,+p18@PCOLCE
Hg19::chr7:150711272..150711306,-p8@ATG9B
Hg19::chr7:150775644..150775650,-p5@FASTK
Hg19::chr8:143751707..143751730,+p2@PSCA
Hg19::chr8:21990868..21990906,-p2@HR
Hg19::chr8:22409352..22409361,+p24@SORBS3
Hg19::chr9:117004510..117004513,+p@chr9:117004510..117004513
+
Hg19::chr9:131903916..131903951,+p8@PPP2R4
Hg19::chr9:134165195..134165202,+p5@PPAPDC3
Hg19::chr9:139282891..139282896,-p@chr9:139282891..139282896
-
Hg19::chr9:21994750..21994776,-p13@CDKN2A
Hg19::chr9:38068437..38068455,-p3@ENST00000540557
Hg19::chrX:69623884..69623886,+p@chrX:69623884..69623886
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0048518positive regulation of biological process0.00140632531219541
GO:0048522positive regulation of cellular process0.00388887713003141
GO:0006917induction of apoptosis0.00392172611206062
GO:0012502induction of programmed cell death0.00392172611206062
GO:0005625soluble fraction0.00392172611206062
GO:0045936negative regulation of phosphate metabolic process0.00392172611206062
GO:0043065positive regulation of apoptosis0.00392172611206062
GO:0043068positive regulation of programmed cell death0.00392172611206062
GO:0042632cholesterol homeostasis0.00392172611206062
GO:0055092sterol homeostasis0.00392172611206062
GO:0055088lipid homeostasis0.00438854313126638
GO:0015918sterol transport0.00438854313126638
GO:0030301cholesterol transport0.00438854313126638
GO:0008034lipoprotein binding0.0107484795777597
GO:0065007biological regulation0.0178024265771723
GO:0050789regulation of biological process0.0191590005068112
GO:0003817complement factor D activity0.0191590005068112
GO:0050749apolipoprotein E receptor binding0.0191590005068112
GO:0032515negative regulation of phosphoprotein phosphatase activity0.0191590005068112
GO:0030229very-low-density lipoprotein receptor activity0.0191590005068112
GO:0032516positive regulation of phosphoprotein phosphatase activity0.0191590005068112
GO:0035305negative regulation of dephosphorylation0.0191590005068112
GO:0035308negative regulation of protein amino acid dephosphorylation0.0191590005068112
GO:0042981regulation of apoptosis0.0259099367043505
GO:0043067regulation of programmed cell death0.0259099367043505
GO:0050794regulation of cellular process0.0259099367043505
GO:0051174regulation of phosphorus metabolic process0.0259099367043505
GO:0019220regulation of phosphate metabolic process0.0259099367043505
GO:0008160protein tyrosine phosphatase activator activity0.0259099367043505
GO:0048156tau protein binding0.0259099367043505
GO:0035306positive regulation of dephosphorylation0.0259099367043505
GO:0035304regulation of protein amino acid dephosphorylation0.0259099367043505
GO:0035307positive regulation of protein amino acid dephosphorylation0.0259099367043505
GO:0010149senescence0.0259099367043505
GO:0008203cholesterol metabolic process0.030957613977377
GO:0042157lipoprotein metabolic process0.0319799892743909
GO:0051496positive regulation of stress fiber formation0.0319799892743909
GO:0051004regulation of lipoprotein lipase activity0.0319799892743909
GO:0051495positive regulation of cytoskeleton organization and biogenesis0.0319799892743909
GO:0032233positive regulation of actin filament bundle formation0.0319799892743909
GO:0031232extrinsic to external side of plasma membrane0.0319799892743909
GO:0043086negative regulation of catalytic activity0.0319799892743909
GO:0016125sterol metabolic process0.0363570142838911
GO:0005319lipid transporter activity0.0370265024419312
GO:0051721protein phosphatase 2A binding0.0374547283925113
GO:0045192low-density lipoprotein catabolic process0.0374547283925113
GO:0032088inhibition of NF-kappaB transcription factor0.0374547283925113
GO:0031589cell-substrate adhesion0.0389496332072172
GO:0035303regulation of dephosphorylation0.0439905280809569
GO:0017166vinculin binding0.0439905280809569
GO:0031324negative regulation of cellular metabolic process0.0444126921707153
GO:0051346negative regulation of hydrolase activity0.0454880282252511
GO:0006423cysteinyl-tRNA aminoacylation0.0454880282252511
GO:0004817cysteine-tRNA ligase activity0.0454880282252511
GO:0033344cholesterol efflux0.0454880282252511
GO:0042159lipoprotein catabolic process0.0454880282252511
GO:0051492regulation of stress fiber formation0.0454880282252511
GO:0032231regulation of actin filament bundle formation0.0454880282252511
GO:0043038amino acid activation0.0456459809016163
GO:0006418tRNA aminoacylation for protein translation0.0456459809016163
GO:0043039tRNA aminoacylation0.0456459809016163
GO:0001953negative regulation of cell-matrix adhesion0.0456459809016163
GO:0043149stress fiber formation0.0456459809016163
GO:0006869lipid transport0.0456459809016163
GO:0016876ligase activity, forming aminoacyl-tRNA and related compounds0.0456459809016163
GO:0016875ligase activity, forming carbon-oxygen bonds0.0456459809016163
GO:0004812aminoacyl-tRNA ligase activity0.0456459809016163
GO:0006915apoptosis0.0456459809016163
GO:0009892negative regulation of metabolic process0.0456459809016163
GO:0012501programmed cell death0.0456459809016163
GO:0030299cholesterol absorption0.0456459809016163
GO:0043410positive regulation of MAPKKK cascade0.0456459809016163
GO:0000045autophagic vacuole formation0.0456459809016163
GO:0042627chylomicron0.0456459809016163
GO:0044241lipid digestion0.0456459809016163
GO:0050750low-density lipoprotein receptor binding0.0456459809016163
GO:0045471response to ethanol0.0456459809016163
GO:0000267cell fraction0.0469230363482118
GO:0045736negative regulation of cyclin-dependent protein kinase activity0.0469230363482118
GO:0016236macroautophagy0.0469230363482118
GO:0006707cholesterol catabolic process0.0469230363482118
GO:0016127sterol catabolic process0.0469230363482118
GO:0048168regulation of neuronal synaptic plasticity0.0469230363482118
GO:0016265death0.0469230363482118
GO:0008219cell death0.0469230363482118
GO:0050892intestinal absorption0.0498827202411778
GO:0001540beta-amyloid binding0.0498827202411778
GO:0022408negative regulation of cell-cell adhesion0.0498827202411778



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

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