MCL coexpression mm9:655

Phase1 CAGE Peaks

	Short description
Mm9::chr11:55854487..55854525,-	p1@Nmur2
Mm9::chr11:57886520..57886533,-	p1@ENSMUST00000137124
Mm9::chr11:57886538..57886549,-	p2@ENSMUST00000137124
Mm9::chr12:105247210..105247245,-	p@chr12:105247210..105247245 -
Mm9::chr15:101361561..101361569,-	p@chr15:101361561..101361569 -
Mm9::chr17:14398060..14398061,+	p@chr17:14398060..14398061 +
Mm9::chr2:155140315..155140326,-	p@chr2:155140315..155140326 -
Mm9::chr3:92169070..92169078,+	p3@Sprr2f
Mm9::chr3:92169100..92169115,+	p1@Sprr2f
Mm9::chr3:92169958..92169968,+	p@chr3:92169958..92169968 +
Mm9::chr7:148248944..148248945,-	p@chr7:148248944..148248945 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0001607	neuromedin U receptor activity	0.00657408166816525
GO:0042924	neuromedin U binding	0.00657408166816525
GO:0001533	cornified envelope	0.0244772157503047
GO:0007566	embryo implantation	0.0244772157503047
GO:0030216	keratinocyte differentiation	0.0244772157503047
GO:0031424	keratinization	0.0244772157503047
GO:0009913	epidermal cell differentiation	0.0244772157503047
GO:0042923	neuropeptide binding	0.0244772157503047
GO:0008188	neuropeptide receptor activity	0.0244772157503047
GO:0042698	menstrual cycle	0.0244772157503047
GO:0007565	female pregnancy	0.0244772157503047
GO:0048730	epidermis morphogenesis	0.0268096031911463
GO:0032504	multicellular organism reproduction	0.0303963336594432
GO:0048609	reproductive process in a multicellular organism	0.0303963336594432
GO:0048729	tissue morphogenesis	0.0303963336594432
GO:0007218	neuropeptide signaling pathway	0.0303963336594432
GO:0030594	neurotransmitter receptor activity	0.0303963336594432
GO:0042165	neurotransmitter binding	0.0303963336594432
GO:0008544	epidermis development	0.0303963336594432
GO:0007398	ectoderm development	0.0303963336594432
GO:0001653	peptide receptor activity	0.0303963336594432
GO:0008528	peptide receptor activity, G-protein coupled	0.0303963336594432
GO:0042277	peptide binding	0.0370275566252879

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
female reproductive system	1.37e-27	9
female organism	1.24e-22	11
female reproductive organ	3.00e-20	8
internal female genitalia	1.54e-18	5
vagina	2.31e-11	1
oviduct	4.58e-11	1
uterus or analog	5.74e-11	1
tongue	7.19e-11	1
gustatory system	7.19e-11	1
future tongue	7.19e-11	1
embryonic uterus	7.23e-11	4
uterus	7.23e-11	4
internal genitalia	1.33e-10	9
reproductive structure	1.09e-09	26
reproductive system	1.09e-09	26
orifice	8.42e-09	5
reproductive organ	5.42e-07	24
adult organism	6.56e-07	51

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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